Canal calcique
Les canaux calciques sont des protéines membranaires qui régulent le flux d'ions calcium dans et hors des cellules, ce qui est essentiel pour diverses fonctions cellulaires, y compris la contraction musculaire, la libération de neurotransmetteurs et l'expression génique. La dysrégulation de l'activité des canaux calciques est associée à des conditions telles que l'hypertension, les arythmies cardiaques et les troubles neurologiques. Chez CymitQuimica, nous proposons une large sélection de modulateurs des canaux calciques pour soutenir vos recherches en santé cardiovasculaire, neurobiologie et transduction du signal.
493 produits trouvés pour "Canal calcique"
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NAADP tetrasodium salt
CAS :<p>Ca2+ mobilizing agent</p>Formule :C21H27N6O18P3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :744.39Ryanodine
CAS :<p>Ryanodine: a diterpenoid modulating Ca2+ release via ryanodine receptors; concentration-dependent effects; found in Ryania speciosa; toxic.</p>Formule :C25H35NO9Degré de pureté :98%Couleur et forme :White SolidMasse moléculaire :493.553Ion Channel Targeted Library
<p>A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;</p>Couleur et forme :Odour SolidCalcium Channel Compound Library
<p>A unique collection of 140 calcium channel blockers and agonists for high throughput and high content screening;</p>Couleur et forme :Odour SolidKT-362 free base
CAS :<p>KT-362 is a calcium channel blocker with antihypertensive properties that can be used in the study of cardiovascular disease.</p>Formule :C22H28N2O3SDegré de pureté :99.76%Couleur et forme :SoildMasse moléculaire :400.53Candidalysin
CAS :<p>Candidalysin is a cytolytic peptide toxin initially isolated from *Candida albicans*, exhibiting both toxic and non-toxic properties. It activates epithelial cell signaling pathways by interacting with the epithelial growth factor receptor (EGFR) on host cells, leading to the activation of matrix metalloproteinases (MMP) and calcium ion influx, which results in inflammatory responses and immune cell recruitment. Additionally, Candidalysin exhibits cytotoxicity by causing membrane damage to host cells.</p>Formule :C153H266N38O38S2Couleur et forme :SolidMasse moléculaire :3310.11Fasudil
CAS :<p>Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.</p>Formule :C14H17N3O2SDegré de pureté :99.79% - 99.84%Couleur et forme :SolidMasse moléculaire :291.37Levamlodipine besylate Hemipentahydrate
CAS :<p>Levamlodipine besylate hemipentahydrate is the besylate hemipentahydrate salt form of Levamlodipine. It is an orally effective calcium channel blocker with antioxidative and vasodilatory properties. This compound can reduce serum malondialdehyde (MDA) levels, enhance the activity of superoxide dismutase (SOD), and alleviate oxidative stress. Levamlodipine besylate hemipentahydrate is relevant for research in vascular dementia, hypertension, and cerebrovascular diseases.</p>Formule :C20H25ClN2O5·C6H6O3SH2OCouleur et forme :SolidMasse moléculaire :1224.1817R(18S)-EpETE
CAS :<p>17R(18S)-EpETE: Oxylipin, eicosapentaenoic acid metabolite, activates BKCa channels, has negative chronotropic effects.</p>Formule :C20H30O3Couleur et forme :SolidMasse moléculaire :318.457Lyso-Globotriaosylceramide (d18:1)
CAS :<p>Lyso-Gb3, lacking fatty acyl, binds Stx1 with cholesterol and phosphatidylcholine, not Stx2; lowers neutrophil viability; accumulates in Fabry disease.</p>Formule :C36H67NO17Couleur et forme :SolidMasse moléculaire :785.922Cyclic ADP-ribose ammonium
<p>cADPR ammonium is a second messenger that boosts cytosolic calcium via Ryanodine receptors and TRPM2 channels.</p>Couleur et forme :LiquidILS-920
CAS :<p>ILS-920, a Rapamycin analog, has reduced immunosuppression, enhanced neuroprotection, and preferentially binds FKBP52 and L-type VGCC β1.</p>Formule :C57H86N2O14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1023.3Chlorocresol
CAS :<p>Chlorocresol (4-Chloro-3-methylphenol) is an antiseptic medication.</p>Formule :C7H7ClOCouleur et forme :SolidMasse moléculaire :142.58PDDHV
CAS :<p>PDDHV: a capsaicin-like vanilloid selective for rat TRPV1; induces Ca2+ uptake in neurons, EC50 of 70 nM.</p>Formule :C49H72O11Couleur et forme :SolidMasse moléculaire :837.09Flosatidil
CAS :<p>Flosatidil is a small molecule voltage-gated calcium channel complex (VDCCs) blocker for the treatment of neurological disorders and cardiovascular diseases,</p>Formule :C26H34F3N3O3SDegré de pureté :98.29% - 99.60%Couleur et forme :SolidMasse moléculaire :525.63ω-Conotoxin GVIA
CAS :<p>Peptide neurotoxin; selectively and reversibly blocks N-type calcium channels (IC50 = 0.15 nM). Reduces (RS)-3,5-DHPG -induced long term depression in vivo.</p>Formule :C120H182N38O43S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3037Mast cell degranulating peptide (28-49)
CAS :<p>Mast cell degranulating peptide (28-49) is a bee venom depolarizer that can improve the cGMP content of cerebellum tablets in mice.</p>Formule :C110H196N40O24S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2591.25GTx1-15
<p>GTx1-15, an inhibitor cystine knot (ICK) peptide, antagonizes the voltage-dependent calcium channel Cav3.1, as well as voltage-dependent sodium channels Nav1.3</p>Formule :C176H271N53O45S7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4073.82(±)5(6)-DiHETE
CAS :<p>Eicosapentaenoic acid is an ω-3 polyunsaturated fatty acid that is abundant in marine organisms and fish oils.</p>Formule :C20H32O4Couleur et forme :SolidMasse moléculaire :336.472sFTX-3.3
CAS :<p>sFTX-3.3 is a calcium ion channel antagonist, exhibiting IC50 values of approximately 0.24 mM and 0.70 mM against P-type and N-type channels respectively.</p>Formule :C12H29N7OCouleur et forme :SolidMasse moléculaire :287.412
