Canal calcique
Les canaux calciques sont des protéines membranaires qui régulent le flux d'ions calcium dans et hors des cellules, ce qui est essentiel pour diverses fonctions cellulaires, y compris la contraction musculaire, la libération de neurotransmetteurs et l'expression génique. La dysrégulation de l'activité des canaux calciques est associée à des conditions telles que l'hypertension, les arythmies cardiaques et les troubles neurologiques. Chez CymitQuimica, nous proposons une large sélection de modulateurs des canaux calciques pour soutenir vos recherches en santé cardiovasculaire, neurobiologie et transduction du signal.
493 produits trouvés pour "Canal calcique"
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Nicardipine-d3 hydrochloride
CAS :<p>Nicardipine D3 hydrochloride is the deuterium labeled Nicardipine hydrochloride.</p>Formule :C26H30ClN3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :519YM-244769 dihydrochloride
CAS :<p>YM-244769 dihydrochloride is an effective inhibitor of Na+/Ca2+ exchange 3 (NCX3) with an IC50 of 18 nM.</p>Formule :C26H24Cl2FN3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :516.39HSK16149
CAS :<p>HSK16149 is a novel ligand of voltage-gated calcium channel (VGCC) α 2 δ subunit with analgesic activity.</p>Formule :C12H19NO2Couleur et forme :SolidMasse moléculaire :209.28MRS1845
CAS :<p>MRS1845 is a selective inhibitor of store-operated calcium (SOC) channel (IC50 of 1.7 μM).</p>Formule :C21H22N2O6Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :398.41(S)-Nicardipine
CAS :<p>(S)-Nicardipine is the less active S enantiomer of Nicardipine. Nicardipine is a blocker of calcium channel(IC50 of 1 μM for blocking cardiac calcium channels).</p>Formule :C26H29N3O6Couleur et forme :SolidMasse moléculaire :479.53Almorexant hydrochloride
CAS :<p>Almorexant hydrochloride (ACT 078573 hydrochloride) is a dual orexin receptor antagonist that induces apoptosis and can be used to study sleep disorders.</p>Formule :C29H32ClF3N2O3Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :549.02Norverapamil-d7
CAS :<p>Norverapamil D7 is a deuterium labeled Norverapamil . Norverapamil is a blocker of L-type calcium channel and an inhibitor of P-glycoprotein (P-gp) function .</p>Formule :C26H36N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :447.62Hexadecylphosphoserine TFA
<p>Hexadecylphosphoserine is a type of phospholipid molecule that incorporates a long-chain alkyl group (hexadecyl) and a phosphatidylserine group, granting it high affinity for cell membranes. This compound exhibits antitumor activity by modulating [Ca++]i and related signaling pathways, making it useful for breast cancer research.</p>Formule :C21H41F3NO8PCouleur et forme :SolidMasse moléculaire :523.52Dronedarone
CAS :<p>Dronedarone (SR 33589) is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.</p>Formule :C31H44N2O5SDegré de pureté :98.85% - 99.58%Couleur et forme :SolidMasse moléculaire :556.76Azumolene
CAS :<p>Azumolene (EU4093 free base)</p>Formule :C13H9BrN4O3Degré de pureté :98.1% - 98.35%Couleur et forme :SolidMasse moléculaire :349.14Ginsenoside Rd
CAS :<p>Ginsenoside Rd (Gypenoside VIII) may have properties that inhibit or prevent the growth of tumors.</p>Formule :C48H82O18Degré de pureté :99.13% - 99.92%Couleur et forme :SolidMasse moléculaire :947.15JNJ-26990990
CAS :<p>"JNJ-26990990: broad-spectrum anticonvulsant, less side effects than topiramate, potential for pain and depression treatment; Phase II in 2007."</p>Formule :C9H10N2O2S2Degré de pureté :97.37%Couleur et forme :SolidMasse moléculaire :242.32Efonidipine
CAS :<p>Efonidipine (NZ-105)(NZ-105) is a dihydropyridine calcium channel blocker, blocking both T-type and L-type calcium channels.</p>Formule :C34H38N3O7PDegré de pureté :98.35% - 99.47%Couleur et forme :SolidMasse moléculaire :631.66Bepridil hydrochloride
CAS :<p>Bepridil hydrochloride (CERM 1978) is a calcium channel blocker and also inhibits Na+/Ca2+ exchange (NCX), sodium channels and cardiac sarcolemmal KATP channels</p>Formule :C24H35ClN2ODegré de pureté :99.45% - 99.68%Couleur et forme :SolidMasse moléculaire :4032,5-Di-tert-butylhydroquinone
CAS :<p>2,5-Di-tert-butylhydroquinone (BHQ) is an effective and selective endoplasmic reticulum Ca2+-ATPase inhibitor.</p>Formule :C14H22O2Degré de pureté :97.11%Couleur et forme :PelletslargecrystalsMasse moléculaire :222.32DHBP dibromide
CAS :<p>DHBP dibromide (1,1'-DI-N-HEPTYL-4,4'-BIPYRIDINIUM DIBRO) is calcium release and a muscle relaxant inhibitor.</p>Formule :C24H38Br2N2Degré de pureté :99.73%Couleur et forme :Yellow To Yellow-Green Powder Or FlakesMasse moléculaire :514.38L-Phenylalanine
CAS :<p>L-Phenylalanine (3-Phenyl-L-alanine) is an essential amino acid and the precursor of the amino acid tyrosine, acts as an antagonist at α2δ calcium channels.</p>Formule :C9H11NO2Degré de pureté :99.37% - 99.87%Couleur et forme :Solid CrystallineMasse moléculaire :165.19GSK1016790A
CAS :<p>GSK1016790A (GSK101) (GSK101) is a novel, potent activator of TRPV4 (transient receptor potential vanilloid 4) with EC50 of 34 nM in choroid plexus epithelial</p>Formule :C28H32Cl2N4O6S2Degré de pureté :97.37% - 99.38%Couleur et forme :SolidMasse moléculaire :655.61Propiverine hydrochloride
CAS :<p>Propiverine is a widely used antimuscarinic drug with a mixed mode of action in the treatment of symptoms associated with overactive bladder (OAB).</p>Formule :C23H30ClNO3Degré de pureté :99.93%Couleur et forme :White Crystalling PowerMasse moléculaire :403.94Dantrolene sodium hemiheptahydrate
CAS :<p>Dantrolene depresses excitation-contraction coupling in skeletal muscle by binding to the ryanodine receptor 1 and decreasing intracellular calcium</p>Formule :C14H9N4NaO5·5H2ODegré de pureté :99.72%Couleur et forme :Orange PowderMasse moléculaire :399.29Pranidipine
CAS :<p>Pranidipine (OPC-13340) is a novel, long-acting 1,4-dihydropyridine calcium channel blocker.</p>Formule :C25H24N2O6Degré de pureté :99.95%Couleur et forme :Yellow SolidMasse moléculaire :448.47Aranidipine
CAS :<p>Aranidipine (MPC1304) (MPC1304) is a calcium channel antagonist with potent and long-lasting antihypertensive effects.</p>Formule :C19H20N2O7Degré de pureté :99.15%Couleur et forme :SolidMasse moléculaire :388.37(±)-Praeruptorin A
CAS :<p>(±)-Praeruptorin A could exhibit its anti-osteoclastogenic activity by inhibiting p38/Akt-c-Fos-NFATc1 signaling and PLCγ-independent Ca(2+) oscillation.</p>Formule :C21H22O7Degré de pureté :98.9% - 99.73%Couleur et forme :SolidMasse moléculaire :386.4(+)-Kavain
CAS :<p>(+)-Kavain ((R)-KAWAIN) is one of the six major kavalactones found in the Piper methysticum (kava) plant; reversible inhibitor of MAO-B.</p>Formule :C14H14O3Degré de pureté :97% - ≥95%Couleur et forme :White Fine PowderMasse moléculaire :230.26Suvecaltamide
CAS :<p>Suvecaltamide (MK-8998) as potent inhibitors of T-type calcium channels.</p>Formule :C20H23F3N2O2Degré de pureté :99.29% - 99.70%Couleur et forme :SolidMasse moléculaire :380.4NS-638
CAS :<p>NS-638 is a Ca2+-channel blocker. It can block K+-stimulated intracellular Ca2+-elevation (IC50: 3.4 μM).</p>Formule :C15H11ClF3N3Degré de pureté :98.44%Couleur et forme :SolidMasse moléculaire :325.72NFAT Inhibitor-2
CAS :<p>NFAT Inhibitor-2 is a compound used as a molecular building block.</p>Formule :C22H20F2N2O4SDegré de pureté :97.37%Couleur et forme :SolidMasse moléculaire :446.47Efonidipine hydrochloride monoethanolate
CAS :<p>Efonidipine HCl monoethanolate is a calcium blocker, boosts dehydroepiandrosterone sulfate in NCI-H295R cells.</p>Formule :C36H45ClN3O8PDegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :714.18Praeruptorin E
CAS :<p>Praeruptorin C/E relaxes arteries, reduces heart contractility, acting like calcium blockers. D/E protect mice from acid lung injury by halting PMNs and IL-6.</p>Formule :C24H28O7Degré de pureté :98.04% - 99.95%Couleur et forme :SolidMasse moléculaire :428.47SR33805
CAS :<p>SR33805 is a potent antagonist of Ca2+ channel(EC50s of 4.1 nM and 33 nM in depolarized and polarized conditions, respectively)</p>Formule :C32H40N2O5SDegré de pureté :99.15%Couleur et forme :SolidMasse moléculaire :564.74Ibutilide Fumarate
CAS :<p>Ibutilide Fumarate is a class III antiarrhythmic, prolonging action potentials by enhancing sodium influx, and can extend QT interval.</p>Formule :(C20H36N2O3S)2·C4H4O4Degré de pureté :99.68% - 99.74%Couleur et forme :SolidMasse moléculaire :885.23Azumolene sodium anhydrous
CAS :<p>Azumolene sodium, a muscle relaxant, blocks calcium release from muscles and halts SOCE linked to RyR1 except when induced by thapsigargin.</p>Formule :C13H8BrN4NaO3Couleur et forme :SolidMasse moléculaire :371.13Argireline
CAS :<p>Argireline (Acetyl hexapeptide-3) is a peptide that inhibits neurotransmitter release, reducing wrinkles.</p>Formule :C34H60N14O12SDegré de pureté :96.79% - 99.65%Couleur et forme :White PowderMasse moléculaire :888.99TGR5 Receptor Agonist
CAS :<p>TGR5 is a potent TGR5(GPCR19) agonist.</p>Formule :C18H14Cl2N2O2Degré de pureté :99.77% - ≥95%Couleur et forme :SolidMasse moléculaire :361.22Ethacrynic acid
CAS :<p>Ethacrynic acid (Edecrin) 是谷胱甘肽 S-转移酶抑制剂，也是NF-κB 信号传导途径的有效抑制剂，并且还调节白三烯的形成。它还可抑制 L 型电压依赖性和储存操作的钙通道，从而导致气道平滑肌细胞松弛。它是利尿剂，具有抗炎特性，可减轻类维生素 A 诱导的小鼠耳部水肿。</p>Formule :C13H12Cl2O4Degré de pureté :98.61% - 99.85%Couleur et forme :Crystals Physical Description White Solid (Ntp 1992)Masse moléculaire :303.14Glaucine
CAS :<p>Glaucine: antitussive, antioxidative, antiviral, may fight arthritis, boosts IL-10, hinders breast cancer cell spread by inhibiting MMP-9 and NF-κB.</p>Formule :C21H25NO4Degré de pureté :99.42% - 99.56%Couleur et forme :SolidMasse moléculaire :355.43HC-056456
CAS :<p>HC-056456 (3,4-Bis(2-thienoyl)-1,2,5-oxadiazole-N-oxide) is a CatSper channel modulator.</p>Formule :C12H6N2O4S2Degré de pureté :99.62% - 99.65%Couleur et forme :SolidMasse moléculaire :306.32Psoralenoside
CAS :<p>Psoralenoside: a compound from Psoralea fruit; has estrogenic, osteoblastic, antitumor, and antibacterial properties.</p>Formule :C17H18O9Degré de pureté :99.03% - 99.49%Couleur et forme :SolidMasse moléculaire :366.32Quadrol
CAS :<p>Quadrol (EDTP) is an immunostimulant, accelerated wound healing.</p>Formule :C14H32N2O4Degré de pureté :99.91% - 99.92%Couleur et forme :Viscous Liquid Liquid ViscousMasse moléculaire :292.41Mirogabalin
CAS :<p>Mirogabalin (DS5565) is a calcium channel blocker with analgesic effects.</p>Formule :C12H19NO2Degré de pureté :98.57%Couleur et forme :SolidMasse moléculaire :209.28Efonidipine hydrochloride
CAS :<p>Efonidipine HCl (NZ-105) blocks T-type/L-type calcium channels; used in hypertension treatment.</p>Formule :C34H39ClN3O7PCouleur et forme :SolidMasse moléculaire :668.12NP118809
CAS :<p>NP118809 (39-1B4) is a potent N-type calcium channel blocker(IC50 : 0.11 μM).</p>Formule :C32H32N2ODegré de pureté :97.74% - 98.68%Couleur et forme :SolidMasse moléculaire :460.61Praeruptorin C
CAS :<p>Praeruptorin C: an antioxidant, calcium antagonist, protects neurons, reduces vascular hypertrophy, affects cellular signals.</p>Formule :C24H28O7Degré de pureté :99.6% - 99.92%Couleur et forme :SolidMasse moléculaire :428.47CDN1163
CAS :<p>CDN1163 is a small molecule activator of sarco/endoplasmic reticulum Ca2+-ATPase (SERCA).</p>Formule :C20H20N2O2Degré de pureté :99.83% - ≥95%Couleur et forme :SolidMasse moléculaire :320.39ABT-639 hydrochloride
CAS :<p>ABT-639 hydrochloride is a selective, novel T-type Ca2+ channel blocker.</p>Formule :C20H21Cl2F2N3O3SCouleur et forme :SolidMasse moléculaire :492.36Pyr6
CAS :<p>Pyr6 (N-[4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-3-fluoro-4-pyridinecarboxamide) is a selective TRPC3 inhibitor with IC50 of 0.49 uM(Ca2+ influx</p>Formule :C17H9F7N4ODegré de pureté :98.89%Couleur et forme :SolidMasse moléculaire :418.27Gabapentin hydrochloride
CAS :<p>Gabapentin hydrochloride (Neurontin HCl) is a GABA analogue, used to treat seizures and neuropathic pain.</p>Formule :C9H17NO2·HClDegré de pureté :99.71%Couleur et forme :Off-White SolidMasse moléculaire :207.7Pinaverium bromide
CAS :<p>Pinaverium bromide is an calcium channel blocker with Antispasmodic and effectively relieves pain, diarrhea and intestinal discomfort.</p>Formule :C26H41Br2NO4Degré de pureté :99.52%Couleur et forme :White Crystalline PowderMasse moléculaire :591.42Taurolithocholic acid sodium salt
CAS :<p>Taurolithocholic acid sodium salt (Sodium taurolithocholate) is the major human metabolite, a bile acid which inhibits radioligand binding to muscarinic M1, but</p>Formule :C26H44NNaO5SDegré de pureté :99.79% - 99.93%Couleur et forme :SolidMasse moléculaire :505.69FPL64176
CAS :<p>FPL64176 is a L-type calcium channels activator.</p>Formule :C22H21NO3Degré de pureté :98.68%Couleur et forme :SolidMasse moléculaire :347.41
