Canal calcique
Les canaux calciques sont des protéines membranaires qui régulent le flux d'ions calcium dans et hors des cellules, ce qui est essentiel pour diverses fonctions cellulaires, y compris la contraction musculaire, la libération de neurotransmetteurs et l'expression génique. La dysrégulation de l'activité des canaux calciques est associée à des conditions telles que l'hypertension, les arythmies cardiaques et les troubles neurologiques. Chez CymitQuimica, nous proposons une large sélection de modulateurs des canaux calciques pour soutenir vos recherches en santé cardiovasculaire, neurobiologie et transduction du signal.
572 produits trouvés pour "Canal calcique"
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Sulcardine 2HCl
CAS :Sulcardine 2HCl is a multi-ion channel blocker that blocks the properties of hERG and hNav1.5 channels and can be used to study atrial fibrillation.Formule :C24H35Cl2N3O4SDegré de pureté :99.33% - 99.76%Couleur et forme :SoildMasse moléculaire :532.523Ziconotide
CAS :Ziconotide: analgesic from cone snail for severe, chronic pain; synthetic ω-conotoxin.Formule :C102H172N36O32S7Degré de pureté :98%Couleur et forme :White PowderMasse moléculaire :2639.13Budiodarone tartrate
CAS :Budiodarone tartrate (ATI-2042 tartrate) is an antiarrhythmic agent that inhibits calcium channels, and can be used in atrial fibrillation research.Formule :C31H37I2NO11Degré de pureté :97.44%Couleur et forme :SolidMasse moléculaire :853.44Ref: TM-T74678
1mg166,00€5mg402,00€10mg652,00€25mg1.238,00€50mg1.932,00€100mg2.721,00€1mL*10mM (DMSO)626,00€ω-Conotoxin FVIA
ω-Conotoxin FVIA is an inhibitor of N-type Ca²⁺ channels (Caᵥ2.2), shown to alleviate mechanical and thermal pain abnormalities in a rat model of caudal nerveFormule :C98H164N36O33S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2566.96Calcium Channel Compound Library
A unique collection of 140 calcium channel blockers and agonists for high throughput and high content screening;Couleur et forme :Odour SolidRef: TM-L7200
1mgÀ demander30μL*10mM (DMSO)À demander50μL*10mM (DMSO)À demander100μL*10mM (DMSO)À demander250μL*10mM (DMSO)À demanderω-Agatoxin TK
CAS :Selective blocker of CaV2.1 P/Q-type calcium channels.Formule :C215H337N65O70S10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :5273.02Huwentoxin I
CAS :Huwentoxin I (HWTX-I) is a peptide toxin that targets and inhibits both voltage-gated sodium channels and N-type calcium channels.Formule :C161H246N48O44S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3750.36Ser-Ala-alloresact acetate
Ser-Ala-alloresact acetate is a sperm-activating peptide (SAP) that is released by marine invertebrate eggs and plays an important role in fertilization.Formule :C44H75N13O16S2Degré de pureté :98.52%Couleur et forme :SolidMasse moléculaire :1106.28Vesnarinone HCl
Vesnarinone HCl is an oral PDE3 inhibitor improving heart contractility, affecting calcium and potassium flux. Used in heart failure research.Formule :C22H26ClN3O4Degré de pureté :99.17%Couleur et forme :SoildMasse moléculaire :431.91Myoregulin TFA
Myoregulin (MLN peptide) TFA, belonging to the regulin family, is a regulator of muscle performance through modulation of intracellular calcium dynamics.Formule :C239H391N53O67S3·xC2HF3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :5175.17 (free base)(±)5(6)-DiHETE
CAS :Eicosapentaenoic acid is an ω-3 polyunsaturated fatty acid that is abundant in marine organisms and fish oils.Formule :C20H32O4Couleur et forme :SolidMasse moléculaire :336.472Chlorocresol
CAS :Chlorocresol (4-Chloro-3-methylphenol) is an antiseptic medication.Formule :C7H7ClOCouleur et forme :SolidMasse moléculaire :142.58Ethyl 4-chloro-2-oxo-1,2-dihydroquinoline-3-carboxylate
CAS :ethyl 4-chloro-2-oxo-1,2-dihydroquinoline-3-carboxylate inhibits NAD(P)H: quinone oxidoreductase 1.Formule :C12H10ClNO3Degré de pureté :99.17%Couleur et forme :SolidMasse moléculaire :251.67Caloxin 3A1
Caloxin 3A1, a biologically active peptide, is a member of the caloxins, which are inhibitors of the extracellular plasma membrane (PM) Ca2+ pumps.Formule :C83H126N22O30Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1912.02Cyclic ADP-ribose ammonium
cADPR ammonium is a second messenger that boosts cytosolic calcium via Ryanodine receptors and TRPM2 channels.Couleur et forme :Liquidω-Conotoxin CVIF
ω-Conotoxin CVIF is a selective inhibitor of Ca v 2.2 channels, demonstrating an IC50 value of 34.3 nM in isolated rat DRG neurons.Formule :C101H170N40O33S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2665.07Levamlodipine besylate Hemipentahydrate
CAS :Levamlodipine besylate hemipentahydrate is the besylate hemipentahydrate salt form of Levamlodipine. It is an orally effective calcium channel blocker with antioxidative and vasodilatory properties. This compound can reduce serum malondialdehyde (MDA) levels, enhance the activity of superoxide dismutase (SOD), and alleviate oxidative stress. Levamlodipine besylate hemipentahydrate is relevant for research in vascular dementia, hypertension, and cerebrovascular diseases.Formule :C20H25ClN2O5·C6H6O3SH2OCouleur et forme :SolidMasse moléculaire :1224.18MCU-i11
CAS :MCU-i11 is a novel negative modulator of the MCU, binding MICU1 and impairing muscle cell growth.Formule :C28H28N4O5SDegré de pureté :98.3%Couleur et forme :SolidMasse moléculaire :532.61Ref: TM-T9960
1mg152,00€5mg340,00€10mg485,00€25mg802,00€50mg1.099,00€100mg1.485,00€1mL*10mM (DMSO)400,00€KT-362 free base
CAS :KT-362 is a calcium channel blocker with antihypertensive properties that can be used in the study of cardiovascular disease.Formule :C22H28N2O3SDegré de pureté :99.91%Couleur et forme :SoildMasse moléculaire :400.53MMK 1
CAS :Potent hFPR2 agonist; EC50: 1 nM (mFPR2), 2 nM (hFPR2), >10,000 nM (hFPR1). Induces monocyte/neutrophil migration, boosts IL-1β/IL-6, activates NADPH-oxidase.Formule :C75H123N19O18SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1610.97Candidalysin
CAS :Candidalysin is a cytolytic peptide toxin initially isolated from *Candida albicans*, exhibiting both toxic and non-toxic properties. It activates epithelial cell signaling pathways by interacting with the epithelial growth factor receptor (EGFR) on host cells, leading to the activation of matrix metalloproteinases (MMP) and calcium ion influx, which results in inflammatory responses and immune cell recruitment. Additionally, Candidalysin exhibits cytotoxicity by causing membrane damage to host cells.Formule :C153H266N38O38S2Couleur et forme :SolidMasse moléculaire :3310.11Flunarizine
CAS :Flunarizine is an orally administered peripheral vasodilator, a dual blocker of voltage-gated Na+/Ca2+ channels and a D2 dopamine receptor antagonist.Formule :C26H26F2N2Degré de pureté :99.9%Couleur et forme :SolidMasse moléculaire :404.50Fasudil
CAS :Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.Formule :C14H17N3O2SDegré de pureté :99.79% - 99.84%Couleur et forme :SolidMasse moléculaire :291.37Lnd 796
CAS :Lnd 796 is an aminosteroid related to LND 623.Formule :C27H45NO7Couleur et forme :SolidMasse moléculaire :495.65Maurocalcine TFA
Maurocalcine TFA acts as an agonist for ryanodine receptor (RyR) channels 1, 2, and 3, demonstrating cell-penetrating capabilities. It induces binding of [3H]ryanodine to RyR1 with an EC50 of 2558 nM and exhibits an apparent affinity of 14 nM for RyR2. This compound is applicable for in vivo cell tracking or other cellular imaging techniques.Formule :C156H270N56O46S6·xC2HF3O2Couleur et forme :SolidMasse moléculaire :3858.55 (free base)PD 0299685
CAS :PD 0299685 is a potent α2δ ligand of the Ca2+ channel for the treatment of interstitial cystitis.Formule :C10H21NO2Degré de pureté :97.20%Couleur et forme :SoildMasse moléculaire :187.28WU-07047
CAS :WU-07047 is a simplified analog of the selective Gαq/11 inhibitor YM-25489.Formule :C39H58N4O11Couleur et forme :SolidMasse moléculaire :758.90N-Palmitoyl Glycine
CAS :Acyl amides like AEA modulate pain/inflammation. PalGly, similar to N-acyl ethanolamines, inhibits nociception and induces calcium influx in cells.Formule :C18H35NO3Couleur et forme :SolidMasse moléculaire :313.48YM-244769 dihydrochloride
CAS :YM-244769 dihydrochloride is an effective inhibitor of Na+/Ca2+ exchange 3 (NCX3) with an IC50 of 18 nM.Formule :C26H24Cl2FN3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :516.39YM-244769
CAS :YM-244769 (3-Pyridinecarboxamide, N-[(3-aminophenyl)methyl]-6-[4-[(3-fluorophenyl)methoxy]phenoxy]-) is an effective inhibitor of Na+/Ca2+ exchange 3 (NCX3)Formule :C26H22FN3O3Degré de pureté :95.62%Couleur et forme :SolidMasse moléculaire :443.47MRS1845
CAS :MRS1845 is a selective inhibitor of store-operated calcium (SOC) channel (IC50 of 1.7 μM).Formule :C21H22N2O6Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :398.41Almorexant hydrochloride
CAS :Almorexant hydrochloride (ACT 078573 hydrochloride) is a dual orexin receptor antagonist that induces apoptosis and can be used to study sleep disorders.Formule :C29H32ClF3N2O3Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :549.02(R)-(+)-Bay-K-8644
CAS :(R)-(+)-Bay-K-8644, a Ca2+ channel agonist, is a dihydropyridine agonist that induces central respiratory depression and inhibits platelet activation in cats.
Formule :C16H15F3N2O4Degré de pureté :96.51% - 96.51%Couleur et forme :SolidMasse moléculaire :356.3Catharanthine
CAS :Catharanthine ((+)-3,4-Didehydrocoronaridine) suppresses nicotinic receptor-mediated diaphragm contractions (IC50=59.6 μM).Formule :C21H24N2O2Degré de pureté :99.11%Couleur et forme :White PowderMasse moléculaire :336.43CCT129957
CAS :CCT129957 is a novel and potent phospholipase C-γ (PLC-γ) inhibitor with an IC50 of about 3 μM and a GC50 of 15 μM.CCT129957 exhibits anticancer activity andFormule :C17H15N3O3Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :309.32Ref: TM-T14903
1mg44,00€5mg93,00€10mg126,00€25mg220,00€50mg330,00€100mg497,00€500mg1.054,00€1mL*10mM (DMSO)92,00€TPC2-A1-N
CAS :TPC2-A1-N is a TPC2 small molecule agonist that can be used to detect different functions of TPC2 channels in intact cells.Formule :C17H9Cl2F3N2O2Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :401.17(S)-Lercanidipine D3 hydrochloride
CAS :(S)-Lercanidipine D3 hydrochloride is a deuterium labeled Lercanidipine D3 hydrochloride. (S)-Lercanidipine hydrochloride is an agent of antihypertensive.Formule :C36H42ClN3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :651.21Norverapamil-d7 HCl
CAS :Norverapamil-d7 HCl (D591-d7 HCl) is a 2H-labeled Norverapamil HCl, a calcium channel blocker and P-gp inhibitor, also a coronary vasodilator.Formule :C26H37ClN2O4Couleur et forme :SolidMasse moléculaire :484.08(R)-Nicardipine
CAS :(R)-Nicardipine is the less active R enantiomer of Nicardipine. Nicardipine is a blocker of calcium channel(IC50 of 1 μM for blocking cardiac calcium channels).Formule :C26H29N3O6Couleur et forme :SolidMasse moléculaire :479.53β-Cyfluthrin
CAS :β-Cyfluthrin is a type II synthetic pyrethroid compound commonly utilized as an active ingredient in agricultural insecticide products.Formule :C22H18Cl2FNO3Couleur et forme :SolidMasse moléculaire :434.29(R)-Lercanidipine-d3 hydrochloride
CAS :(R)-lercanidipine D3 hydrochloride is a deuterium labeled (R)-Lercanidipine hydrochloride. (R)-Lercanidipine D3 (hydrochloride) is a calcium channel blocker.Formule :C36H42ClN3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :651.21Nicardipine-d3 hydrochloride
CAS :Nicardipine D3 hydrochloride is the deuterium labeled Nicardipine hydrochloride.Formule :C26H30ClN3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :519HSK16149
CAS :HSK16149 is a novel ligand of voltage-gated calcium channel (VGCC) α 2 δ subunit with analgesic activity.Formule :C12H19NO2Couleur et forme :SolidMasse moléculaire :209.28A 839977
CAS :A 839977 is a P2X7 receptor antagonist with analgesic activity that inhibits BzATP-induced calcium efflux from the P2X7 receptor for the study of renal fibrosisFormule :C19H14Cl2N6ODegré de pureté :98.01%Couleur et forme :SolidMasse moléculaire :413.26(S)-Nicardipine
CAS :(S)-Nicardipine is the less active S enantiomer of Nicardipine. Nicardipine is a blocker of calcium channel(IC50 of 1 μM for blocking cardiac calcium channels).Formule :C26H29N3O6Couleur et forme :SolidMasse moléculaire :479.53Norverapamil-d7
CAS :Norverapamil D7 is a deuterium labeled Norverapamil . Norverapamil is a blocker of L-type calcium channel and an inhibitor of P-glycoprotein (P-gp) function .Formule :C26H36N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :447.62Hexadecylphosphoserine TFA
Hexadecylphosphoserine is a type of phospholipid molecule that incorporates a long-chain alkyl group (hexadecyl) and a phosphatidylserine group, granting it high affinity for cell membranes. This compound exhibits antitumor activity by modulating [Ca++]i and related signaling pathways, making it useful for breast cancer research.Formule :C21H41F3NO8PCouleur et forme :SolidMasse moléculaire :523.52Magnesium sulfate
CAS :Magnesium sulfate: anticonvulsant for eclampsia, tocolytic agent.Formule :MgSO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :120.37Etripamil
CAS :Etripamil is a fast-acting intranasal L-type calcium-channel blocker for Paroxysmal Supraventricular Tachycardia.Formule :C27H36N2O4Degré de pureté :99.47% - 99.83%Couleur et forme :SolidMasse moléculaire :452.59Ref: TM-T15257
1mg52,00€2mg74,00€5mg110,00€10mg169,00€25mg295,00€50mg447,00€100mg670,00€200mg1.054,00€Dronedarone
CAS :Dronedarone (SR 33589) is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.Formule :C31H44N2O5SDegré de pureté :98.85% - 99.99%Couleur et forme :SolidMasse moléculaire :556.76
