Canal calcique
Les canaux calciques sont des protéines membranaires qui régulent le flux d'ions calcium dans et hors des cellules, ce qui est essentiel pour diverses fonctions cellulaires, y compris la contraction musculaire, la libération de neurotransmetteurs et l'expression génique. La dysrégulation de l'activité des canaux calciques est associée à des conditions telles que l'hypertension, les arythmies cardiaques et les troubles neurologiques. Chez CymitQuimica, nous proposons une large sélection de modulateurs des canaux calciques pour soutenir vos recherches en santé cardiovasculaire, neurobiologie et transduction du signal.
573 produits trouvés pour "Canal calcique"
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JTV-519 hemifumarate
CAS :JTV-519 hemifumarate: Ca2+ blocker, SERCA inhibitor, ryanodine receptor partial agonist; antiarrhythmic, cardioprotective.Formule :C54H68N4O8S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :965.28Methsuximide
CAS :Methsuximide is an anticonvulsant agent which appeared to be effective in petit mal, psychomotor and focal motor attacks [1].Formule :C12H13NO2Couleur et forme :Crystals From Dilute Alcohol SolidMasse moléculaire :203.243',4'-Dichlorobenzamil HCl
CAS :3',4'-Dichlorobenzamil HCl is an inhibitor of Na+ transport, Na+/Ca2+ exchanger, sarcoplasmic reticulum Ca2+ release channels.Formule :C13H12Cl3N7ODegré de pureté :98%Couleur et forme :Yellow SolidMasse moléculaire :388.64BAY-Y-5959
CAS :BAY-Y-5959, a calcium channel agonist, is used potentially for the treatment of arrhythmia, heart failure and myocardial.Formule :C26H24N4O2Couleur et forme :SolidMasse moléculaire :424.49Aladorian
CAS :Aladorian (ARM036), a benzothiazepine, has anti-arrhythmic properties for heart failure and CPVT research.Formule :C12H13NO4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :267.3Aprindine hydrochloride
CAS :Aprindine HCl, a Class 1b antiarrhythmic, treats heart arrhythmias, outperforming digoxin in delaying atrial fibrillation. It's effective orally.Formule :C22H31ClN2Couleur et forme :SolidMasse moléculaire :358.95Levamlodipine gentisate
CAS :Levamlodipine gentisate, an active amlodipine enantiomer, is a dihydropyridine calcium channel blocker for treating hypertension and angina.Formule :C27H31ClN2O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :563Cavα2δ1&NET-IN-2
CAS :Cavα2δ1&NET-IN-2 .Formule :C22H26N6O2SCouleur et forme :SolidMasse moléculaire :438.55TDN345
CAS :TDN345 is a antagonist of Ca2+, for the treatment of vascular and senile dementia including Alzheimer's disease.Formule :C28H34F2N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :468.58Nemadipine-A
CAS :Nemadipine A blocks L-type Ca2+ channels, alters C. elegans morphology, boosts TRAIL's cancer kill rate, and lowers Survivin in A549 cells.Formule :C19H18F5NO4Couleur et forme :SolidMasse moléculaire :419.34Ned-K
CAS :Ned-K blocks NAADP, reduces heart ischemia-reperfusion calcium waves.Formule :C31H31N5O3Couleur et forme :SolidMasse moléculaire :521.61ML218
CAS :ML218 is an inhibitor of T-type Ca2+ channels (Cav3.1, Cav3.2, Cav3.3).ML218 inhibits the synaptic activity of subthalamic nucleus (STN) neurons.Formule :C19H26Cl2N2ODegré de pureté :99.2% - 99.45%Couleur et forme :SolidMasse moléculaire :369.33S-312-d
CAS :S-312d is a calcium channel antagonist. S-312-d can offer marked neuronal protective effects against ischemic injury.Formule :C20H22N2O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :386.46piCRAC-1
CAS :piCRAC-1 is a powerful inhibitor of the photoinducible Ca2+ release-activated Ca2+ (CRAC) channel.Formule :C17H10F6N4Couleur et forme :SolidMasse moléculaire :384.28Niguldipine Free Base
CAS :Niguldipine Free Base is a calcium channel blocker and a₁-adrenergic receptor antagonist and a clinical modulator of multidrug resistance.
Formule :C36H39N3O6Degré de pureté :98.97%Couleur et forme :SolidMasse moléculaire :609.71CGP 28392
CAS :CGP 28392 is used as a partial calcium channel agonist.Formule :C18H17F2NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :365.33SB-237376 HCl
CAS :SB-237376 HCl (SB-237376 hydrochloride) is a calcium and potassium channel antagonist used in the treatment of cardiac arrhythmias.Formule :C20H26ClN3O5Degré de pureté :98.70%Couleur et forme :SolidMasse moléculaire :423.89TMB 8 (hydrochloride)
CAS :TMB 8 blocks nAChRs (IC50: 390-480 nM), reduces Ca2+ in muscles, hinders rabbit aorta contraction at 50 μM, and inhibits PKC dose-dependently.Formule :C22H38ClNO5Couleur et forme :White SolidMasse moléculaire :431.99Sadopine
CAS :Sadopine is a high-affinity radioligand for DHP receptor in L-type Ca2+ channels, suitable for tissue and membrane labeling.Formule :C30H40F3N3O7SCouleur et forme :SolidMasse moléculaire :643.71Lercanidipine. (R)-
CAS :(R)-Lercanidipine enantiomer: antihypertensive, blocks L-type Ca2+ channels, dilates blood vessels.Formule :C36H41N3O6Couleur et forme :SolidMasse moléculaire :611.73TTA-P2
CAS :TTA-P2: potent CNS-penetrating T-type Ca2+ channel blocker; eliminates Cav3.1 window currents.Formule :C21H29Cl2FN2O2Couleur et forme :SolidMasse moléculaire :431.37Leconotide
CAS :Leconotide is a calcium channel blocker and antihyperalgesia agent; isolated from the venom of the cone snail, Conus catus.Formule :C107H179N35O36S7Couleur et forme :SolidMasse moléculaire :2756.23IDO1-IN-19
CAS :IDO1-IN-19 (Compound 17) is a potent inhibitor of IDO1 and has potential for cancer disease research.Formule :C25H22F4N2O3Couleur et forme :SolidMasse moléculaire :474.45CXL-1020
CAS :CXL-1020, a HNO prodrug, enhances heart muscle function & relaxation, aiding in heart failure research.Formule :C7H9NO5S2Couleur et forme :SolidMasse moléculaire :251.28JTV-519
CAS :K201 (JTV-519) is a Ca2+-dependent blocker and prevents abnormal Ca(2+) leak from the sarcoplasmic reticulum in the ischemic heart and skeletal muscle (SkM) byFormule :C25H33ClN2O2SDegré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :461.06Ref: TM-T24239
1mg60,00€5mg110,00€10mg155,00€25mg248,00€50mg365,00€100mg545,00€500mg1.188,00€1mL*10mM (DMSO)134,00€PD-217014 HCl
CAS :PD-217014, a GABA analog, blocks (3)H-gabapentin on alpha(2)delta calcium channels (K(i) 18 nmol/l), and is a visceral analgesic.Formule :C11H19NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :197.27Ricinelaidic Acid
CAS :Ricinelaidic acid blocks LTB4 receptors; hampers human neutrophil responses; reduces rat bronchoconstriction by 46% at 1 mg/kg i.v.Formule :C18H34O3Couleur et forme :SolidMasse moléculaire :298.46Cavα2δ1&NET-IN-1
CAS :Cavα2δ1&NET-IN-1 .Formule :C23H26N4O2SCouleur et forme :SolidMasse moléculaire :422.54Mci 176
CAS :Mci 176 is a quinazolinone calcium antagonist.Formule :C24H32ClN3O4Couleur et forme :SolidMasse moléculaire :461.98SM-6586
CAS :SM-6586 is a potent calcium channel antagonist with inhibitory effects on Na+/H+ and Na+/Ca2+ exchange channels, and can be used in the study of cerebrovascularFormule :C26H27N5O5Degré de pureté :99.43%Couleur et forme :SolidMasse moléculaire :489.52PPZ2
CAS :PPZ2 is a novel DAG-activated TRPC3/TRPC6/TRPC7 channels activator.Formule :C22H29N3O2Couleur et forme :SolidMasse moléculaire :367.48Aladorian sodium
CAS :Aladorian sodium is used for Treatment of Cardiovascular Diseases.Formule :C12H13NNaO4SCouleur et forme :SolidMasse moléculaire :290.29Kadethrin
CAS :Kadethrin is a synthetic pyrethroid. It was used as a pesticide.Formule :C23H24O4SDegré de pureté :98%Couleur et forme :Yellow-Brown Viscous Oil SolidMasse moléculaire :396.5N-Salicyloyltryptamine
CAS :N-Salicyloyltryptamine (STP): a tryptamine with anticonvulsant, anti-inflammatory, analgesic effects; inhibits Na+, Ca2+, K+ channels (IC50 34.6 μM).Formule :C17H16N2O2Couleur et forme :SolidMasse moléculaire :280.32PAQ
CAS :PAQ protects neurons in Parkinson's models at 10 μM; prevents neuron loss in mice substantia nigra with 25-50 mg/kg doses.Formule :C14H11N3Couleur et forme :SolidMasse moléculaire :221.26YS-035 hydrochloride
CAS :inhibitor of outward K+ currentsFormule :C21H30ClNO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :395.92Ro 18-3981
CAS :Ro 18-3981 inhibits myocardial Ca2+ channels; KD is 1.0 nM, close to IC50 for ICa block (2.3 nM).Formule :C24H33N3O8SCouleur et forme :SolidMasse moléculaire :523.6Azelnidipine, (R)-
CAS :Azelnidipine is an L-type CCB that improves HF severity and cardiac nerve activity in HT and HFpEF compared to cilnidipine.Formule :C33H34N4O6Couleur et forme :SolidMasse moléculaire :582.65SR-33805
CAS :SR-33805: calcium channel blocker for atherosclerosis/heart failure, enhances myocyte function, modulates myofilament phosphorylation.Formule :C32H40N2O5SCouleur et forme :SolidMasse moléculaire :564.74Norbormide
CAS :Norbormide is a toxic compound used as a rodenticide. It has several mechanisms of action, acting as a vasoconstrictor and calcium channel blocker.Formule :C33H25N3O3Degré de pureté :98%Couleur et forme :Crystals From Methylene Chloride + Ether Norbormide Is A Colorless To Off-White Crystalline Powder Used As A Selective Rat Poison (Epa 1998)Masse moléculaire :511.57Teludipine hydrochloride
CAS :Teludipine hydrochloride is a blocker of lipophilic calcium channel.Formule :C28H39ClN2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :535.07ORM-10962
CAS :ORM-10962 is a potent, highly selective inhibitor of sodium-calcium exchanger (NCX) (for the reverse and forward mode inhibition with IC50 values of 67 and 55Formule :C27H29N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :459.54trans-Ned 19
CAS :trans-Ned 19 blocks NAADP and TPC, hindering calcium signaling and aorta relaxation at low histamine levels.Formule :C30H31FN4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :514.59AZD-2066 hydrochloride
CAS :AZD-2066 hydrochloride is an mGlu5 antagonist.Formule :C19H17Cl2N5O2Couleur et forme :SolidMasse moléculaire :418.28Anipamil
CAS :Anipamil is a long-acting blocker of calcium channel,and for the treatment of cardiovascular disease.Formule :C34H52N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :520.79(S)-Lercanidipine hydrochloride
CAS :(S)-Lercanidipine hydrochloride is the S-enantiomer of Lercanidipine hydrochloride. (S)-lercanidipine hydrochloride is a potent blocker of calcium channel.Formule :C36H42ClN3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :648.19Palonidipine HCl
CAS :Palonidipine HCl is a calcium channel antagonist potentially for the treatment of angina pectoris and hypertension.Formule :C29H35ClFN3O6Couleur et forme :SolidMasse moléculaire :576.06YM 244769 hydrochloride
CAS :inhibitor of the reverse mode of Na+/Ca2+ exchange (NCX)Formule :C26H23ClFN3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :479.93SOCE inhibitor 1
CAS :SOCE inhibitor 1 is a inhibitor of store-operated calcium entry (SOCE)(IC50 of 4.4 μM).Formule :C25H22F3N5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :513.47TTA-Q6
CAS :TTA-Q6 is a T-type Ca2+ channel antagonist that inhibits the uptake of extracellular calcium ions by tumour cells for the treatment of neurological diseases.Formule :C20H15ClF3N3ODegré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :405.8
