Canal calcique
Les canaux calciques sont des protéines membranaires qui régulent le flux d'ions calcium dans et hors des cellules, ce qui est essentiel pour diverses fonctions cellulaires, y compris la contraction musculaire, la libération de neurotransmetteurs et l'expression génique. La dysrégulation de l'activité des canaux calciques est associée à des conditions telles que l'hypertension, les arythmies cardiaques et les troubles neurologiques. Chez CymitQuimica, nous proposons une large sélection de modulateurs des canaux calciques pour soutenir vos recherches en santé cardiovasculaire, neurobiologie et transduction du signal.
578 produits trouvés pour "Canal calcique".
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Halofuginone
CAS :Halofuginone (RU-19110) inhibits prolyl-tRNA synthetase (Ki=18.3 nM), down-regulates Smad3, and blocks TGF-β at 10 ng/ml.Formule :C16H17BrClN3O3Degré de pureté :99.53%Couleur et forme :Yellow SolidMasse moléculaire :414.68Ref: TM-T6856
1mg34,00€5mg82,00€1mL*10mM (DMSO)92,00€10mg116,00€25mg227,00€50mg344,00€100mg517,00€500mg1.134,00€Verapamil
CAS :Verapamil (CP-16533-1), an oral calcium channel blocker, inhibits P-gp and CYP3A4, used for hypertension, arrhythmias, and angina research.Formule :C27H38N2O4Degré de pureté :99.61% - 99.93%Couleur et forme :White OilMasse moléculaire :454.6Ref: TM-T20656
10mg34,00€25mg49,00€1mL*10mM (DMSO)52,00€50mg70,00€100mg90,00€200mg136,00€500mg219,00€AH-1058 HCl
CAS :AH-1058 HCl is a lipophilic antiarrhythmic calcium channel blocker.Formule :C30H29ClN2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :501.02Kadethrin
CAS :Kadethrin is a synthetic pyrethroid. It was used as a pesticide.Formule :C23H24O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :396.5UK-52831
CAS :UK-52831, a calcium channel antagonist, is used potentially for the treatment of hypertension and myocardia ischemia.Formule :C22H26Cl2N6O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :525.39JTV-519 hemifumarate
CAS :JTV-519 hemifumarate: Ca2+ blocker, SERCA inhibitor, ryanodine receptor partial agonist; antiarrhythmic, cardioprotective.Formule :C54H68N4O8S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :965.28Ethacrynate Sodium
CAS :Ethacrynate Sodium, a sodium salt, blocks chloride, potassium, and sodium transport mainly in Henle's loop.Formule :C13H12Cl2NaO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :326.12SM-6586
CAS :SM-6586 is a potent calcium channel antagonist with inhibitory effects on Na+/H+ and Na+/Ca2+ exchange channels, and can be used in the study of cerebrovascularFormule :C26H27N5O5Degré de pureté :99.43%Couleur et forme :Yellow SolidMasse moléculaire :489.52Cavα2δ1&NET-IN-1
CAS :Cavα2δ1&NET-IN-1 .Formule :C23H26N4O2SCouleur et forme :SolidMasse moléculaire :422.54CXL-1020
CAS :CXL-1020, a HNO prodrug, enhances heart muscle function & relaxation, aiding in heart failure research.Formule :C7H9NO5S2Couleur et forme :SolidMasse moléculaire :251.28IDO1-IN-19
CAS :IDO1-IN-19 (Compound 17) is a potent inhibitor of IDO1 and has potential for cancer disease research.Formule :C25H22F4N2O3Couleur et forme :SolidMasse moléculaire :474.45Leconotide
CAS :Leconotide is a calcium channel blocker and antihyperalgesia agent; isolated from the venom of the cone snail, Conus catus.Formule :C107H179N35O36S7Couleur et forme :SolidMasse moléculaire :2756.23TTA-P2
CAS :TTA-P2: potent CNS-penetrating T-type Ca2+ channel blocker; eliminates Cav3.1 window currents.Formule :C21H29Cl2FN2O2Couleur et forme :SolidMasse moléculaire :431.37Lercanidipine. (R)-
CAS :(R)-Lercanidipine enantiomer: antihypertensive, blocks L-type Ca2+ channels, dilates blood vessels.Formule :C36H41N3O6Couleur et forme :SolidMasse moléculaire :611.73Sadopine
CAS :Sadopine is a high-affinity radioligand for DHP receptor in L-type Ca2+ channels, suitable for tissue and membrane labeling.Formule :C30H40F3N3O7SCouleur et forme :SolidMasse moléculaire :643.71TMB 8 (hydrochloride)
CAS :TMB 8 blocks nAChRs (IC50: 390-480 nM), reduces Ca2+ in muscles, hinders rabbit aorta contraction at 50 μM, and inhibits PKC dose-dependently.Formule :C22H38ClNO5Couleur et forme :SolidMasse moléculaire :431.99piCRAC-1
CAS :piCRAC-1 is a powerful inhibitor of the photoinducible Ca2+ release-activated Ca2+ (CRAC) channel.Formule :C17H10F6N4Couleur et forme :SolidMasse moléculaire :384.28Ned-K
CAS :Ned-K blocks NAADP, reduces heart ischemia-reperfusion calcium waves.Formule :C31H31N5O3Couleur et forme :SolidMasse moléculaire :521.61Nemadipine-A
CAS :Nemadipine A blocks L-type Ca2+ channels, alters C. elegans morphology, boosts TRAIL's cancer kill rate, and lowers Survivin in A549 cells.Formule :C19H18F5NO4Couleur et forme :SolidMasse moléculaire :419.34TDN345
CAS :TDN345 is a antagonist of Ca2+, for the treatment of vascular and senile dementia including Alzheimer's disease.Formule :C28H34F2N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :468.58Cavα2δ1&NET-IN-2
CAS :Cavα2δ1&NET-IN-2 .Formule :C22H26N6O2SCouleur et forme :SolidMasse moléculaire :438.55AJG-049 HCl
CAS :AJG-049 HCl is a calcium channel antagonist that inhibits L-type Ca2+ channels via diltiazem-binding site(s).Formule :C27H31ClN2O2Couleur et forme :SolidMasse moléculaire :451.01PD-151307
CAS :PD-151307 is used as an N-type calcium channel blocker.Formule :C33H47N3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :565.74(Rac)-MEM 1003
CAS :MEM-1003, a calcium channel blocker, is used potentially for the treatment of bipolar disorders.Formule :C22H25ClN2O5Couleur et forme :SolidMasse moléculaire :432.9RyRs activator 3
CAS :RyRs activator 3 (compound A4) serves as an insecticide highly effective against both the diamondback moths, M.Formule :C23H19BrCl2N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :578.25AMG-1
CAS :AMG-1 inhibits CRAC channels, blocks effector T cells, not regulatory ones, and reduces EAE progression.Formule :C18H9ClF5N3OCouleur et forme :SolidMasse moléculaire :413.73RQ-00311651
CAS :RQ-00311651 is a novel T-type Ca2+ channel blocker. RQ-00311651 also inhibited high K-induced Ca signaling in those cells.Formule :C19H18F3N5O2Couleur et forme :SolidMasse moléculaire :405.37β-Amino Acid Imagabalin Hydrochloride
CAS :β-Amino Acid Imagabalin Hydrochloride is the voltage-dependent calcium channel ligand for the α2δ subunit.Formule :C9H20ClNO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :209.71Lidoflazine
CAS :Lidoflazine: antianginal, blocks HERG K+ & Ca channels, risks QT prolongation & arrhythmia.Formule :C30H35F2N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :491.62Semotiadil recemate fumarate
CAS :Semotiadil recemate fumarate is the recemate of Semotiadil fumarate. Semotiadil fumarate is a novel antagonist of vasoselective Ca2+ channel.Formule :C33H36N2O10SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :652.71Carboxyamidotriazole
CAS :Carboxyamidotriazole is a cytostatic inhibitor of non-voltage-operated calcium channels and calcium channel-mediated signaling pathways.Formule :C17H12Cl3N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :424.67McN5691
CAS :McN5691 is a voltage sensitive calcium channel blocker.Formule :C30H35NO3Degré de pureté :98.08% - 99.38%Couleur et forme :SolidMasse moléculaire :457.6JTV-519
CAS :K201 (JTV-519) is a Ca2+-dependent blocker and prevents abnormal Ca(2+) leak from the sarcoplasmic reticulum in the ischemic heart and skeletal muscle (SkM) byFormule :C25H33ClN2O2SDegré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :461.06Ref: TM-T24239
1mg57,00€5mg104,00€1mL*10mM (DMSO)127,00€10mg146,00€25mg235,00€50mg346,00€100mg515,00€500mg1.125,00€Halofuginone hydrobromide
CAS :Halofuginone specifically inhibits collagen type I and MMP-2 gene expression, which may result in the suppression of angiogenesis and tumor cell growth.Formule :C16H17BrClN3O3·HBrDegré de pureté :97.01% - 99.73%Couleur et forme :SolidMasse moléculaire :495.59Ref: TM-T3524
1mg34,00€2mg49,00€5mg74,00€1mL*10mM (DMSO)84,00€10mg106,00€25mg207,00€50mg310,00€100mg469,00€500mg897,00€18:0 LYSO-PE
CAS :18:0 LYSO-PE is a compound that induces an increase in [Ca2+]i and can be used as a phospholipid (PL) standard for lipid analysis by electrospray mass spectrometry (ESI-MS)/MS.Formule :C23H48NO7PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :481.6DHP-218
CAS :DHP-218, a calcium channel blocker, inhibits rat aorta contractions; pA2: 9.11, IC50: 6.3 nmol/L (high K+) & 66 nmol/L (phenylephrine).Formule :C18H21N2O7PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :408.34N-Salicyloyltryptamine
CAS :N-Salicyloyltryptamine (STP): a tryptamine with anticonvulsant, anti-inflammatory, analgesic effects; inhibits Na+, Ca2+, K+ channels (IC50 34.6 μM).Formule :C17H16N2O2Couleur et forme :SolidMasse moléculaire :280.32A 39355
CAS :A 39355 may specifically overcome multidrug resistance without the serious hypotensive effects associated with calcium antagonists.Formule :C28H39Cl2N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :504.54NP-252
CAS :NP-252 is a calcium channel antagonist potentially for the treatment of angina pectoris and congestive heart failure.Formule :C26H35N3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :469.57KB-130015
CAS :KB-130015, a activator of hERG1 potassium channels, blocks native and recombinant hERG1 channels at high voltages.Formule :C18H14I2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :548.11Watanidipine dihydrochloride
CAS :Watanidipine dihydrochloride is a novel dihydropyridine (DHP)-type calcium channel blocker with slow-onset pharmacological actions.Formule :C41H44Cl2N4O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :759.73Gallopamil, (-)-
CAS :Gallopamil, (-)- is an L-type calcium channel blocker. It is used in the treatment of abnormal heart rhythms.Formule :C28H40N2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :484.63AK-2-38
CAS :AK-2-38 is a nifedipine analogue with potent smooth muscle calcium antagonist action and partial agonist effects on isolated guinea pig left atrium.Formule :C26H30N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :434.53Falipamil
CAS :Falipamil, a verapamil derivative, is a calcium channel blocker with antitachycardic and potential antianginal effects.Formule :C24H32N2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :428.52Tiropramide
CAS :Tiropramide is an antispasmodic drug. It also useful to inhibit the contractile response of the urinary bladder and in managing abdominal pain in IBS.Formule :C28H41N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :467.64Bms 188107
CAS :Bms 188107 is a calcium antagonist, it has cardioprotective effects.Formule :C25H26N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :418.48AZD 2066
CAS :AZD 2066 is a selective, orally active, and brain-penetrant mGluR5 antagonist with analgesic activity.Formule :C19H16ClN5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :381.82BBR 2160
CAS :BBR 2160: a calcium-antagonist dihydropyridine derivative, reduces heart tissue contractility and shortens action potentials.Formule :C21H25N3O7SCouleur et forme :SolidMasse moléculaire :463.5Ronipamil
CAS :Ronipamil is an analogue of verapamil that used as a calcium entry blocker.Formule :C32H48N2Couleur et forme :SolidMasse moléculaire :460.74Lercanidipine, (S)-
CAS :(S)-Lercanidipine: a dihydropyridine calcium blocker with prolonged antihypertensive and kidney-protective properties.Formule :C36H41N3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :611.73
