Canal calcique
Les canaux calciques sont des protéines membranaires qui régulent le flux d'ions calcium dans et hors des cellules, ce qui est essentiel pour diverses fonctions cellulaires, y compris la contraction musculaire, la libération de neurotransmetteurs et l'expression génique. La dysrégulation de l'activité des canaux calciques est associée à des conditions telles que l'hypertension, les arythmies cardiaques et les troubles neurologiques. Chez CymitQuimica, nous proposons une large sélection de modulateurs des canaux calciques pour soutenir vos recherches en santé cardiovasculaire, neurobiologie et transduction du signal.
493 produits trouvés pour "Canal calcique"
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Gallopamil, (-)-
CAS :<p>Gallopamil, (-)- is an L-type calcium channel blocker. It is used in the treatment of abnormal heart rhythms.</p>Formule :C28H40N2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :484.63AK-2-38
CAS :<p>AK-2-38 is a nifedipine analogue with potent smooth muscle calcium antagonist action and partial agonist effects on isolated guinea pig left atrium.</p>Formule :C26H30N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :434.53Falipamil
CAS :<p>Falipamil, a verapamil derivative, is a calcium channel blocker with antitachycardic and potential antianginal effects.</p>Formule :C24H32N2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :428.52Tiropramide
CAS :<p>Tiropramide is an antispasmodic drug. It also useful to inhibit the contractile response of the urinary bladder and in managing abdominal pain in IBS.</p>Formule :C28H41N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :467.64Bms 188107
CAS :<p>Bms 188107 is a calcium antagonist, it has cardioprotective effects.</p>Formule :C25H26N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :418.48AZD 2066
CAS :<p>AZD 2066 is a selective, orally active, and brain-penetrant mGluR5 antagonist with analgesic activity.</p>Formule :C19H16ClN5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :381.82BBR 2160
CAS :<p>BBR 2160: a calcium-antagonist dihydropyridine derivative, reduces heart tissue contractility and shortens action potentials.</p>Formule :C21H25N3O7SCouleur et forme :SolidMasse moléculaire :463.5DS16570511
CAS :<p>DS16570511 is a novel, cell-permeable inhibitor targeting the mitochondrial calcium uniporter.</p>Formule :C30H25Cl2N3O4Degré de pureté :98.34% - 98.45%Couleur et forme :SolidMasse moléculaire :562.44Tamolarizine
CAS :<p>Tamolarizine (Tamolarizine free base) free base is a novel calcium antagonist.</p>Formule :C27H32N2O3Degré de pureté :98.17%Couleur et forme :SoildMasse moléculaire :432.55Tiapamil hydrochloride
CAS :<p>Tiapamil hydrochloride (Ro 11-1781 hydrochloride) is a calcium channel blocker with antihypertensive activity used in the study of angina pectoris.</p>Formule :C26H38ClNO8S2Degré de pureté :99.17%Couleur et forme :SolidMasse moléculaire :592.16R 56865
CAS :<p>R 56865 is a weak potential-operated channel inhibitor that inhibits the late sodium current in human isolated cardiomyocytes.</p>Formule :C23H28FN3OSDegré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :413.55Enecadin
CAS :<p>Enecadin is a neuroprotective agent.</p>Formule :C21H28FN3ODegré de pureté :98.53%Couleur et forme :SolidMasse moléculaire :357.46Clopimozide
CAS :<p>Clopimozide (R-29764), a long-acting oral antischizophrenic, blocks calcium channels and [3H] nilandipine binding.</p>Formule :C28H28ClF2N3ODegré de pureté :98.19% - >99.99%Couleur et forme :SolidMasse moléculaire :495.99GSK205
CAS :<p>GSK205 is a selective TRPV4 antagonist (IC50: 4.19 μM) for inhibiting TRPV4-mediated Ca2+ influx.</p>Formule :C24H25BrN4SDegré de pureté :99.46%Couleur et forme :SolidMasse moléculaire :481.45SAK3
CAS :<p>SAK3 is a modulator of nAChR activity and is used to study memory deficits and Alzheimer's disease.</p>Formule :C20H23N3O4Degré de pureté :98.37% - 99.43%Couleur et forme :SolidMasse moléculaire :369.418-Bromo-cGMP sodium
CAS :<p>8-Bromo-cGMP sodium: PKG activator, eases pain, dilates vessels, reduces Ca2+ currents & insulin release.</p>Formule :C10H10BrN5NaO7PDegré de pureté :99.45%Couleur et forme :SolidMasse moléculaire :446.09Gallopamil
CAS :<p>Gallopamil blocks acid secretion (IC50: 10.9 μM), acts as antiarrhythmic, vasodilator, and is a methoxy Verapamil derivative.</p>Formule :C28H40N2O5Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :484.63Cronidipine
CAS :<p>Cronidipine (LF 20254), a calcium channel antagonist, is used potentially for the treatment of hypertension and myocardia ischemia.</p>Formule :C30H32ClN3O8Degré de pureté :99.47%Couleur et forme :SolidMasse moléculaire :598.04Upacicalcet
CAS :<p>Upacicalcet (AJT-240) is a calcium mimetic for SHPT in dialysis, reducing PTH by targeting parathyroid receptors.</p>Formule :C11H14ClN3O6SDegré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :351.76Vatanidipine
CAS :<p>Vatanidipine (AE0047) is a novel dihydropyridine (DHP)-type calcium channel blocker with slow-onset pharmacological actions.A slow-onset and long-lasting</p>Formule :C41H42N4O6Degré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :686.8Sulcardine sulfate
CAS :<p>Sulcardine sulfate (B-87823) is a multi-ion channel blocker with antiarrhythmic activity that inhibits Na+, K+, and Ca2+ channels.</p>Formule :C24H35N3O8S2Degré de pureté :98.74%Couleur et forme :SolidMasse moléculaire :557.68O-1602
CAS :<p>O-1602 is a novel GPR55 agonist, an atypical cannabinoid associated with the central nervous system and obesity, and is a candidate compound for the treatment</p>Formule :C17H22O2Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :258.36VU 0240551
CAS :<p>VU 0240551 is a selective antagonist of neuronal K-Cl cotransporter KCC2 inhibitor with an IC50 of 560 nM. VU 0240551 inhibits L-type calcium channels and hERG.</p>Formule :C16H14N4OS2Degré de pureté :99.9%Couleur et forme :SolidMasse moléculaire :342.44SERCA2a activator 1
CAS :<p>SERCA2a activator 1 boosts heart function by reducing phospholamban restraint and enhancing cardiac contraction-relaxation cycles.</p>Formule :C32H29N3O4SDegré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :551.66CERM-11956
CAS :<p>Pelretin (BASF 43915) is a potential protein inhibitor for the study of dermatologic diseases.</p>Formule :C29H38N2O7Degré de pureté :99.38%Couleur et forme :SolidMasse moléculaire :526.62Ticolubant
CAS :<p>Ticolubant: Oral LTB4 antagonist, Ki=0.78 nM; blocks Ca2+ migration, IC50=6.6 nM; anti-inflammatory in mice.</p>Formule :C23H19Cl2NO3SDegré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :460.37CP-060
CAS :<p>CP-060 is a potent Ca2+ antagonist and inhibits Ca2+ overload with antioxidant and cardioprotective activities.</p>Formule :C30H42N2O5SDegré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :542.73PD173212
CAS :<p>PD 173212 is a blocker that blocks N-type voltage sensitive calcium channel (Cav2.2).</p>Formule :C38H53N3O3Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :599.85Terflavoxate
CAS :<p>Terflavoxate is a novel, orally active, semisynthetic statin microtubule inhibitor commonly used in combination with capecitabine.</p>Formule :C26H29NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :419.51Cerebrocrast
CAS :<p>Cerebrocrast (IOS-11212) has anti-inflammatory and hypoglycemic activity, blocks human platelet activation, and is used in the study of diabetes.</p>Formule :C26H35F2NO7Degré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :511.56Fenoverine
CAS :<p>Fenoverine (Spasmopriv) has antispasmodic activity and can be used to study gastrointestinal spasms.</p>Formule :C26H25N3O3SDegré de pureté :98.34%Couleur et forme :SolidMasse moléculaire :459.56NecroX-5
CAS :<p>NecroX-5, a derivative of NecroX, exhibits anti-inflammatory and anti-cancer activities. NecroX-5 reduces intracellular calcium concentration.</p>Formule :C27H39N3O9S3Degré de pureté :99.944%Couleur et forme :SolidMasse moléculaire :645.81Diproteverine HCl
CAS :<p>Diproteverine HCl is a novel calcium antagonist with antianginal properties, antispasmodic and vasoactive.</p>Formule :C26H36ClNO4Degré de pureté :98.55% - 99.84%Couleur et forme :SolidMasse moléculaire :462.02Opc 8490
CAS :<p>Opc 8490 is a cardiotonic agent and a positive inotropic vasodilator, which prolongs the atrial action potential in a concentration-dependent manner.</p>Formule :C30H35N3O10Degré de pureté :98.88%Couleur et forme :SolidMasse moléculaire :597.61Lifarizine
CAS :<p>Lifarizine (RS-87476), a calcium-sodium channel antagonist, shows neuroprotective activity in a simplified rat survival model of double vessel occlusion.</p>Formule :C29H32N4Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :436.59AZD-1305
CAS :<p>AZD-1305: novel anti-arrhythmic blocking IKr, Ca, Na currents; useful in arrhythmia research.</p>Formule :C22H31FN4O4Degré de pureté :99.31% - 99.86%Couleur et forme :SolidMasse moléculaire :434.5N106
CAS :<p>N106 is an activator of the SUMO-activating enzyme, E1 ligase, and triggers intrinsic sumoylation of SERCA2a. N106 can be used in studies about heart failure.</p>Formule :C17H14N4O3SDegré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :354.38Crobenetine
CAS :<p>Crobenetine (BIII 890 CL) Free Base is a selective NaV channel blocker that eliminates VTD-induced [Ca2+] elevation.</p>Formule :C25H33NO2Degré de pureté :98.99%Couleur et forme :SolidMasse moléculaire :379.54Mioflazine
CAS :<p>Mioflazine suppresses nucleoside uptake. Mioflazine is an orally active nucleoside transport inhibitor. It has the potential for sleep disorders treatment.</p>Formule :C29H30Cl2F2N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :575.48Iganidipine
CAS :<p>Iganidipine（NKY 722） is a new water-soluble Ca2+ antagonist with antihypertensive activity for research and neurological related diseases.</p>Formule :C28H38N4O6Degré de pureté :96.3%Couleur et forme :SolidMasse moléculaire :526.62RS 5773
CAS :<p>RS 5773 is a benzothiazepine derivative with antianginal effects.</p>Formule :C29H33ClN2O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :541.1Budiodarone
CAS :<p>Budiodarone (ATI-2042) resembles amiodarone, potentially preventing atrial fibrillation.</p>Formule :C27H31I2NO5Couleur et forme :SolidMasse moléculaire :703.35Coelenterazine h
CAS :<p>Coelenterazine H, a Ca2+ sensitive synthetic derivative, is a luminescent biomolecule used to measure Ca2+ changes.</p>Formule :C26H21N3O2Degré de pureté :99.49%Couleur et forme :Yellow To Brownish PowderMasse moléculaire :407.46TROX-1
CAS :<p>TROX-1 is the activation state-dependent Cav2 channel antagonist.</p>Formule :C22H16ClFN6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :434.85Piprofurol
CAS :<p>Piprofurol is used as a Calcium channel blocker.</p>Formule :C26H33NO6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :455.54A 425619
CAS :<p>A 425619 (1-(4-(TRIFLUOROMETHYL)BENZYL)-3-(ISOQUINOLIN-5-YL)UREA) is a potent TRPV1 antagonist</p>Formule :C18H14F3N3ODegré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :345.32Cavα2δ1&NET-IN-3
CAS :<p>Cavα2δ1&NET-IN-3 (example 216) is an inhibitor targeting both the α2δ subunit of voltage-gated calcium channels (VGCC) and the noradrenaline transporter (NET).</p>Formule :C24H30N6O2SCouleur et forme :SolidMasse moléculaire :466.6N-type calcium channel blocker-1
CAS :<p>N-type calcium channel blocker-1 is an orally active analgesic agent,shows high affinity to functionally block N-type calcium channels.</p>Formule :C31H47N3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :461.73(S)-(-)-Bay-K-8644
CAS :<p>(S)-(-)-Bay-K-8644 ((S)-(-)-Bay K 8644) is an agonist of L-type Ca2+ channel and activates Ba2+ currents with an EC50 of 32 nM.</p>Formule :C16H15F3N2O4Degré de pureté :98.28% - 99.37%Couleur et forme :SolidMasse moléculaire :356.3KCa1.1 channel activator-1
<p>A selective vascular KCa1.1 channel stimulator with CaV1.2 blocking ability and mild myorelaxant effects.</p>Formule :C25H16O10Couleur et forme :SolidMasse moléculaire :476.39
