Canal calcique
Les canaux calciques sont des protéines membranaires qui régulent le flux d'ions calcium dans et hors des cellules, ce qui est essentiel pour diverses fonctions cellulaires, y compris la contraction musculaire, la libération de neurotransmetteurs et l'expression génique. La dysrégulation de l'activité des canaux calciques est associée à des conditions telles que l'hypertension, les arythmies cardiaques et les troubles neurologiques. Chez CymitQuimica, nous proposons une large sélection de modulateurs des canaux calciques pour soutenir vos recherches en santé cardiovasculaire, neurobiologie et transduction du signal.
573 produits trouvés pour "Canal calcique"
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MP-010
CAS :MP-010 is an FKBP12 ligand that regulates cytosolic calcium by stabilizing RyR channel activity. It facilitates functional improvement in SOD1G93A mice with amyotrophic lateral sclerosis (ALS), evidenced by enhanced motor coordination, increased integrity of neuromuscular junctions, and significantly higher spinal motor neuron survival rates. MP-010 is applicable for research in the field of neurological disorders.Formule :C14H20N4O2SCouleur et forme :SolidMasse moléculaire :308.399T-Type calcium channel inhibitor 2
Compound 6g inhibits T-type Ca channels (IC50: Cav3.1-31μM, Cav3.2-83μM), cytotoxic to A549 (IC50: 5μM) & HCT-116 cells (IC50: 6.4μM).Formule :C36H39FN4OSCouleur et forme :SolidMasse moléculaire :594.78SR 33805 oxalate
CAS :Ca2+ channel antagonistFormule :C34H42N2O9SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :654.77AZD 2066 hydrate
AZD 2066 hydrate is a selective, orally active, and brain-penetrant antagonist of mGluR5. It exhibits antinociceptive effects [1].Formule :C19H18ClN5O3Couleur et forme :SolidMasse moléculaire :386.33Leualacin
CAS :Leualacin is a novel calcium blocker from Hapsidospora irregularis.Formule :C31H47N3O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :573.72IAB15
CAS :IAB15 is a potent inhibitor of T-type calcium channel that can be used in the research of epilepsy [1].Formule :C15H14F3NO2Couleur et forme :SolidMasse moléculaire :297.27SB-423557
CAS :SB-423557 is an orally active antagonist of calcium-sensing receptor (CaR) with IC50 of 520 nMFormule :C28H36N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :464.60BER-5
CAS :BER-5 is a potent MrgX2 antagonist, demonstrating broad-spectrum antagonistic activity against various MrgX2 agonists. It can inhibit Substance P(SP)-induced degranulation in LAD2 cells and alleviate SP-induced allergic reactions in mice. BER-5 is useful for researching mechanisms related to allergic reactions.Formule :C20H16O4Couleur et forme :SolidMasse moléculaire :320.34PDE1-IN-4
PDE1-IN-4: inhibits PDE1C/A/B with IC50s 10/145/354 nM, may help study idiopathic pulmonary fibrosis.Formule :C33H33N3O4Couleur et forme :SolidMasse moléculaire :535.63Cav 3.1 blocker 1
CAS :Cav 3.1 blocker 1 (compound 12) is a T-type calcium channel inhibitor with an IC50 value of 160 nM for Cav3.1. It exhibits weaker inhibition on Cav 3.2 with an IC50 of 5000 nM and shows no inhibitory effect on Cav 3.3 and Cav 1.2 (IC50 > 10000 nM).Formule :C26H19F6N3O2Couleur et forme :SolidMasse moléculaire :519.438(Rac)-PD0299685
CAS :(Rac)-PD0299685 is a potent voltage-dependent calcium channel inhibitor for the study of retina-related diseases.
Formule :C10H21NO2Degré de pureté :97.20%Couleur et forme :SolidMasse moléculaire :187.28Verapamil EP Impurity C hydrochloride
CAS :NSC-609249 hydrochloride, an impurity of Verapamil, is a calcium channel blocker with potent orally active properties. It also functions as a first-generation P-glycoprotein (P-gp) inhibitor.Formule :C12H20ClNO2Couleur et forme :SolidMasse moléculaire :245.75Fostedil
CAS :Fostedil enhances heart function, maintains blood flow during partial/total coronary occlusions, and lowers aortic pressure.Formule :C18H20NO3PSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :361.4
