Récepteur GABA
Les récepteurs GABA sont les principaux récepteurs de neurotransmetteurs inhibiteurs du système nerveux central, jouant un rôle crucial dans la régulation de l'excitabilité neuronale et le maintien de l'équilibre entre excitation et inhibition. La dysfonction des récepteurs GABA est impliquée dans divers troubles neurologiques et psychiatriques, notamment l'épilepsie, l'anxiété et la dépression. Chez CymitQuimica, nous proposons une gamme complète de modulateurs des récepteurs GABA pour soutenir vos recherches en neurobiologie, santé mentale et développement thérapeutique.
365 produits trouvés pour "Récepteur GABA"
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Ro 22-8515
CAS :Ro 22-8515 is the ligand of benzodiazepine receptor.Formule :C18H12Cl2N2OCouleur et forme :SolidMasse moléculaire :343.21Ro15-4513
CAS :Ro15-4513 is imidazobenzodiazepinone derivative and is a partial inverse agonist of benzodiazepine receptors. Ro15-4513 is an effective ethanol antagonist.Formule :C15H14N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :326.31ZK-91296
CAS :ZK-91296: GABA agonist, lowers anxiety without sedation, may target specific BZ receptor subtype.Formule :C23H22N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :390.432-Hydroxysaclofen
CAS :2-Hydroxysaclofen is a GABAB receptor antagonist.Formule :C9H12ClNO4SDegré de pureté :98%Couleur et forme :White SolidMasse moléculaire :265.71SCH-50910 free base
CAS :SCH-50910 is an antagonist of GABAB receptor.Formule :C8H15NO3Couleur et forme :SolidMasse moléculaire :173.21CGS 20625
CAS :partial agonist for the benzodiazepine binding site of the GABAA receptorFormule :C18H19N3O2Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :309.36Profadol hydrochloride
CAS :Profadol hydrochloride acts as a mixed agonist-antagonist of the μ-opioid receptor with analgesic activity.Formule :C14H22ClNODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :255.78SX-3228
CAS :SX-3228 is a selective agonist of benzodiazepine1 (BZ1) receptor(IC50 of 17 nM).Formule :C18H18N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :338.36Ro 14-7437
CAS :Ro 14-7437 is an antagonist of GABA-benzodiazepine receptor.Formule :C15H15N3O3Couleur et forme :SolidMasse moléculaire :285.3Adinazolam Mesylate
CAS :Adinazolam Mesylate is an anxiolytic and antidepressant agent. Adinazolam Mesylate binds to peripheral-type benzodiazepine receptors that interact allosterically with GABA receptors as an agonist to produce inhibitory effects.Formule :C20H22ClN5O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :447.94Ro 15-1310
CAS :Ro 15-3505, a benzodiazepine receptor partial inverse agonist, has shown the ability to improve impaired recent memory of aged mice.Formule :C15H14ClN3O3Couleur et forme :SolidMasse moléculaire :319.74CP-457920
CAS :CP-457920 is a selective α5 GABAA receptor inverse agonist that is suitable for investigating dementia in Alzheimer's disease.Formule :C18H17N3O3Degré de pureté :99.06% - 99.74%Couleur et forme :SolidMasse moléculaire :323.35Org 20599
CAS :GABAA receptor agonistFormule :C25H40ClNO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :438.04U-101017
CAS :U-101017 is a partial benzodiazepine receptor and GABAA receptor agonist.Formule :C23H27ClN4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :442.94TPA-023B
CAS :TPA-023B: oral GABAA α2/α3 agonist (Kis: 0.73/2 nM), α1 antagonist (Ki: 1.8 nM), non-sedating anxiolytic.Formule :C21H15F2N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :391.37CGP 7930
CAS :Positive allosteric modulator of GABAB receptorsFormule :C19H32O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :292.46SKF 97541
CAS :GABAB agonistFormule :C4H12NO2PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :137.12BHF-177
CAS :BHF-177 is a positive allosteric modulator of the GABAB receptor. BHF-177 reduces self-administration of nicotine in animal studies.Formule :C19H20F3N3Couleur et forme :SolidMasse moléculaire :347.38CGS8216
CAS :CGS8216 shows analgesic activity at high doses, has anxiolytic activity, and can be used to study immune system disorders.Formule :C16H11N3ODegré de pureté :98.53%Couleur et forme :SolidMasse moléculaire :261.28SCH 50911 hydrochloride
CAS :SCH 50911 hydrochloride is a selective, orally-active and competitive antagonist of γ-Aminobutyric acid B GABA(B) receptor(IC50 : 1.1 μM).Formule :C8H16ClNO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :209.67DS2
CAS :Positive allosteric modulator of δ-subunit containing GABAA receptorsFormule :C18H12ClN3OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :353.83(±)-Homoproline Hydrochloride
CAS :(±)-Homoproline Hydrochloride. Affordable Excellence: Reliable Quality You Can TrustFormule :C6H12ClNO2Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :165.62MK-0343
CAS :MK0343 is an orally bioavailable GABAA receptor subtype-selective partial agonist and is a non-sedating anxiolytic.Formule :C19H17F2N7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :397.3817-PA
CAS :17-PA is a GABAA receptor antagonist.Formule :C25H34ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :350.54Bifenazate
CAS :Bifenazate is a positive allosteric modulator of GABA receptor. Bifenazate is an acaricide that controls 100% of mites at a concentration of 25 ppm.Formule :C17H20N2O3Degré de pureté :99.62%Couleur et forme :Solid CrystallineMasse moléculaire :300.35CGP11952
CAS :CGP11952 is same the benzodiazepines in its pharmacological action and it also is an experimental benzodiazepine derivative.Formule :C21H21Cl2N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :446.33E2730
CAS :E2730 is a non-competitive GABA transporter 1 (GAT1) inhibitor with anti-epileptic activity, useful in studying neurological disorders.Formule :C9H8F4N2O2SDegré de pureté :98.22% - 98.54%Couleur et forme :SolidMasse moléculaire :284.23U-89843A
CAS :U-89843A is an allosteric modulator of the GABA_A receptor, known to enhance GABA-induced Cl^- currents [1].Formule :C16H24ClN5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :321.85(R)-Baclofen hydrochloride
CAS :Arbaclofen HCl, a GABA-B agonist, treats spasticity from spinal injury by reducing excitatory transmission.Formule :C10H13Cl2NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :250.12NO 711
CAS :NO 711（NNC-711 free acid） is a selective inhibitor of GAT-1, which enhances non-rapid eye movement sleep, and prevents paclitaxel-induced neuropathic pain.Formule :C21H22N2O3Degré de pureté :99.70%Couleur et forme :SolidMasse moléculaire :350.41AZD 3043
CAS :AZD 3043 (THRX 918661) is a modulator of the gamma-aminobutyric acid type A receptor, a novel sedative-hypnotic, and a potential short-acting anesthetic.Formule :C19H29NO5Degré de pureté :98.19% - 99.55%Couleur et forme :SolidMasse moléculaire :351.44mGAT3/4-IN-1
CAS :mGAT3/4-IN-1 inhibits mGAT3/4 with pIC50: 5.31/5.24, reduces neuropathic pain in diabetic mice.Formule :C26H31ClN2O2S2Couleur et forme :SolidMasse moléculaire :503.12GABAA receptor agent 4
CAS :<p>Compound 1e is a potent γ-GABAAR antagonist with a Ki of 0.18 µM, offering immunomodulatory effects on T cell proliferation.</p>Formule :C17H24N2OCouleur et forme :SolidMasse moléculaire :272.39Ro 19-4603
CAS :Benzodiazepine inverse agonistFormule :C15H17N3O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :319.38TPMPA
CAS :GABAA-ρ antagonistFormule :C6H12NO2PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :161.14TG41
CAS :TG41 is a GABAA receptors positive modulator.Formule :C18H13BrCl2N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :440.12FG8119
CAS :FG8119 is a novel benzodiazepine agonist with potential anticonvulsant and antiepileptic activity for the study of neurological disorders.Formule :C17H15N5O2Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :321.33GABAA receptor agent 6
CAS :GABAA receptor agent 6 (compound 2027) is a potent γ-GABAAR antagonist with low cellular membrane permeability (Ki = 0.56 μM) [1].Formule :C18H25N3O2Couleur et forme :SolidMasse moléculaire :315.41TB 21007
CAS :GABAA receptor inverse agonistFormule :C15H17NO2S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :339.5SL-651498
CAS :SL-651498, a GABAA receptor agonist, is used potentially for the treatment of anxiety.Formule :C23H20FN3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :389.42Bamaluzole
CAS :Bamaluzole is an agonist of GABA receptor.Formule :C14H12ClN3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :273.72ZAPA sulfate
CAS :GABAA receptors agonistFormule :C4H8N2O6S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :244.25Lesogaberan
CAS :Lesogaberan: selective GABAB agonist, EC50 8.6 nM, Ki 5.1 nM in rats, weak GABAA affinity (Ki 1.4 μM).Formule :C3H9FNO2PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :141.08NAP-1
CAS :NAP-1 is an anesthetic that enhances CA1 brain inhibition in rats and causes tadpole sedation (EC50 = 0.53 μM).Formule :C20H18ClNO2Couleur et forme :SolidMasse moléculaire :339.82GABAA receptor agent 7
CAS :Compound 5c, a GABAA receptor modulator with anticonvulsant properties and low neurotoxicity, is promising for epilepsy research.Formule :C18H13ClN4OCouleur et forme :SolidMasse moléculaire :336.77MRK-623
CAS :MRK-623 (14k) is an oral GABA A agonist with high affinity for α1/α2/α3/α5 subunits and anxiolytic properties.Formule :C20H17FN4OCouleur et forme :SolidMasse moléculaire :348.37GABAA receptor agent 8
CAS :Compound 5e, a GABAA receptor modulator, shows potent anticonvulsant effects with low neurotoxicity for epilepsy research.Formule :C19H16N4OCouleur et forme :SolidMasse moléculaire :316.36Etbicyphat
CAS :Etbicyphat: potent GABA(A) antagonist, induces epileptiform activity, binds to GABA/benzodiazepine receptors.Formule :C6H11O4PCouleur et forme :SolidMasse moléculaire :178.12NCS-382
CAS :γ-Hydroxybutyric acid antagonistFormule :C13H14O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :218.25TCS 1105
CAS :TCS 1105 is a GABAA BZR ligand, blocking Sema3A and altering mouse anxiety, aggression, and social dominance.Formule :C17H13FN2O2Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :296.3Pipazethate
CAS :Pipipyrazine is a nonnarcotic oral cough suppressant, cough suppressant.Formule :C21H25N3O3SCouleur et forme :SolidMasse moléculaire :399.51NNC052090
CAS :NNC052090 inhibits GABA uptake, favoring hBGT-1 (Ki=1.4μM), affects α1/D2 receptors (IC50=266/1632nM).Formule :C27H30N2O2Couleur et forme :SolidMasse moléculaire :414.54RU 33965
CAS :RU 33965, a 3-cyclopropyl carbonyl imidazobenzodiazepine, act as a low-efficacy benzodiazepine receptor inverse agonist.Formule :C16H15N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :281.31CGP 36216 hydrochloride
CAS :CGP 36216 hydrochloride is a potent and selective antagonist of GABAB receptors (IC50: 43 μM).Formule :C5H14NO2PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :151.14β-CCB
CAS :benzodiazepine receptor ligandFormule :C16H16N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :268.31GABA-AT-IN-1
CAS :GABA-AT-IN-1 (Compound 6) is an inhibitor of γ-aminobutyric acid transaminase (GABA-AT) that crosses the blood-brain barrier.Formule :C23H18N2O6Couleur et forme :SolidMasse moléculaire :418.4ZK93423
CAS :ZK93423: potent benzodiazepine agonist, IC50=1nM, non-selective, Ki=4.1-6nM for α1-α5 GABAA subunits.Formule :C23H22N2O4Couleur et forme :SolidMasse moléculaire :390.43Pregabalin arenacarbil
CAS :Pregabalin arenacarbil is a gabamimetic.Formule :C15H27NO6Couleur et forme :SolidMasse moléculaire :317.38GABAA receptor modulator-2
CAS :Compound 20: Selective, oral α5-GABAAR inhibitor, Ki: 4.1 nM. High stability, CNS safe.Formule :C22H22FN3O5SCouleur et forme :SolidMasse moléculaire :459.49Carburazepam
CAS :Carburazepam is a derivate of benzodiazepines. Benzodiazepines are a class of psychoactive drugs.Formule :C17H16ClN3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :329.78UMB68 sodium
CAS :UMB-68 is a GHB receptor ligand with no affinity (IC(50) >100 microM) at GABA(A) or GABA(B) receptors.Formule :C6H12NaO3Couleur et forme :SolidMasse moléculaire :155.149Tracazolate hydrochloride
CAS :Tracazolate hydrochloride (Tracazolate (hydrochloride)) is a modulator of the GABAA receptor with anxiolytic and anticonvulsant activity.Formule :C16H25ClN4O2Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :340.85(+)-Nipecotic acid
CAS :(+)-Nipecotic acid ((+)-β-Homoproline) is a specific inhibitor of GABA transport and uptake, capable of activating GABAA receptors.Formule :C6H11NO2Degré de pureté :99.38%Couleur et forme :SolidMasse moléculaire :129.16Phaclofen
CAS :GABAB antagonistFormule :C9H13ClNO3PDegré de pureté :99.32%Couleur et forme :White SolidMasse moléculaire :249.63(S)-SNAP5114
CAS :(S)-SNAP5114 is a selective inhibitor of GABA transport with IC50s of 5 μM for hGAT-3 and 21 μM for rGAT-2. (S)-SNAP5114 has anticonvulsant properties.Formule :C30H35NO6Degré de pureté :98.20%Couleur et forme :SolidMasse moléculaire :505.6Ref: TM-T16831
5mg52,00€10mg78,00€25mg160,00€50mg225,00€100mg325,00€200mg445,00€1mL*10mM (DMSO)51,00€Radequinil
CAS :<p>Radequinil is a benzodiazepine receptor partial inverse agonist. Rade quinil binds to GABA(-) and GABA(+) ligand (Kis: 5.15 and 6.11 nM, respectively).</p>Formule :C18H14N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :334.333α,21-Dihydroxy-5α-pregnan-20-one
CAS :3α,21-Dihydroxy-5α-pregnan-20-one (5alpha-THDOC) is a GABAA modulator that can be used in the study of Alzheimer's-like neurological diseases.Formule :C21H34O3Degré de pureté :98.00%Couleur et forme :SolidMasse moléculaire :334.49HZ166
CAS :HZ-166 is a positive GABAA receptor modulator and a GABAA receptor subtype-selective benzodiazepine site ligand.Formule :C21H16N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :356.38BGT1-IN-9
CAS :BGT1-IN-9 is an M1 muscarinic agonist.Formule :C5H10ClN3O2Couleur et forme :SolidMasse moléculaire :179.605RO 4938581
CAS :RO 4938581: potent GABAA α5 inverse agonist (Ki 4.6 nM); lower affinity for α1β3γ2a, α2β3γ2a, α3β3γ2a (Ki: 174, 185, 80 nM).Formule :C13H8BrF2N5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :352.14Chlormethiazole edisylate
CAS :Chlormethiazole edisylate is a positive allosteric modulator of the GABAA receptor. Chlormethiazole edisylate is a sedative and hypnotic.Formule :C8H14ClNO6S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :351.85COR628
CAS :COR628 is the GABA(B) receptor positive allosteric modulator.Formule :C16H23NO3SCouleur et forme :SolidMasse moléculaire :309.42trans-4-Hydroxycrotonic acid
CAS :ligand of γ-hydroxybutyric acid (GHB) receptorFormule :C4H6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :102.09LY 81067
CAS :LY 81067, a new anticonvulsant, prevents PTZ- and picrotoxin-induced seizures in mice via picrotoxin site interaction.Formule :C22H24N4OCouleur et forme :SolidMasse moléculaire :360.45U 90042
CAS :GABAA receptor ligandFormule :C17H13ClN6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :352.78COR627
CAS :COR627 is the GABA receptor positive allosteric modulator.Formule :C20H27NO3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :361.5CPP-115
CAS :CPP-115 is a GABA-aminotransferase inhibitor and a high-affinity vigabatrin analogue.Formule :C7H9F2NO2Couleur et forme :SolidMasse moléculaire :177.15GABAA receptor agent 5
CAS :Compound 018 is a potent γ-GABAAR antagonist, Ki of 0.020 μM, with low membrane permeability.Formule :C21H25N3O2SDegré de pureté :99.39%Couleur et forme :SolidMasse moléculaire :383.51JY-XHe-053
CAS :JY-XHe-053 is a selective modulator of GABAA receptors.Formule :C22H16FN3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :373.38HIE-124
CAS :HIE-124 is a central cervous system active anticonvulsant and ultra-short acting hypnotic.Formule :C10H12N2O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :240.28Fengabine
CAS :Fengabine (SL-79229) is a GABA receptor agonist with antidepressant activity and is used to treat depression.Formule :C17H17Cl2NODegré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :322.23RWJ-51204
CAS :<p>RWJ-51204: potent adenosine A2A blocker, GABA(A) partial agonist (IC50: 0.2-2 nM), neuroprotective, may treat Parkinson's.</p>Formule :C21H19F2N3O3Degré de pureté :99.57% - 99.95%Couleur et forme :SolidMasse moléculaire :399.39Ref: TM-T16811
1mg333,00€5mg787,00€10mg1.074,00€25mg1.510,00€50mg1.882,00€100mg2.375,00€500mg4.655,00€L-838417
CAS :L-838417 is a GABAA receptor subtype-selective benzodiazepine site-selective ligand and GABAA receptor-positive modulator used in the study of anxiety disordersFormule :C19H19F2N7ODegré de pureté :98.12% - 99.70%Couleur et forme :SolidMasse moléculaire :399.4Nerisopam
CAS :<p>Nerisopam is an agonist of gamma-aminobutyric acid (GABA) receptor.</p>Formule :C18H19N3O2Degré de pureté :97.07%Couleur et forme :SolidMasse moléculaire :309.36Alpidem
CAS :Alpidem (Ananxyl), a non-sedative imidazopyridine anxiolytic, treats anxiety with high benzodiazepine receptor affinity.Formule :C21H23Cl2N3ODegré de pureté :99.56% - 99.97%Couleur et forme :White To Off-White SolidMasse moléculaire :404.33Ref: TM-T26600
1mg62,00€5mg144,00€10mg219,00€25mg393,00€50mg550,00€100mg787,00€500mg1.596,00€1mL*10mM (DMSO)129,00€Panadiplon
CAS :Panadiplon (FG 10571) is a selective gamma-aminobutyric acid receptor agonist and partial agonist of 5GABAA, a benzodiazepine receptor, used in the treatment ofFormule :C18H17N5O2Degré de pureté :98.30% - 98.94%Couleur et forme :SolidMasse moléculaire :335.36DSP-0565
CAS :DSP-0565 is a broad-spectrum anti-epileptic with a high safety margin and effectiveness in several convulsant models.Formule :C14H12FNODegré de pureté :99.51% - 99.56%Couleur et forme :SolidMasse moléculaire :229.25Ref: TM-T11106
1mg115,00€2mg172,00€5mg255,00€10mg374,00€25mg562,00€50mg787,00€100mg1.074,00€500mg2.147,00€1mL*10mM (DMSO)220,00€DMCM hydrochloride
CAS :DMCM hydrochloride is a non-selective fully inverse agonist of benzodiazepine.Formule :C17H19ClN2O4Degré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :350.8Ref: TM-T11061
1mg37,00€2mg49,00€5mg85,00€10mg111,00€25mg250,00€50mg464,00€100mg655,00€1mL*10mM (DMSO)93,00€NNC 05-711
CAS :NNC 05-711 (NO-711 hydrochloride) is a potent and selective inhibitor of GAT-1 (GABA transporter 1), exerting anticonvulsant and analgesic effects.Formule :C21H23ClN2O3Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :386.87Divaplon
CAS :Divaplon is a GABA receptor agonist (IC50: 0.056 µM) that displays non-sedating anxiolytic behavioral characteristics in a rat model of anxiety.Formule :C17H17N3O2Degré de pureté :97.44% - 98.25%Couleur et forme :SolidMasse moléculaire :295.34ELB-139
CAS :ELB-139 is a GABA A receptor agonist. ELB139 increases 5-HT in the striatum and prefrontal cortex of rats.Formule :C14H16ClN3ODegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :277.75Sarmazenil
CAS :Sarmazenil (Ro 15-3505) is a partial inverse agonist at the benzodiazepine receptor and is used in the study of chronic hepatic encephalopathy.Formule :C15H14ClN3O3Degré de pureté :99.46%Couleur et forme :SolidMasse moléculaire :319.74Suriclone
CAS :Suriclone (RP 31264), a cyclic pyrrolidone for anxiety, modulates GABA-A receptors without major sedation.Formule :C20H20ClN5O3S2Degré de pureté :99.21% - 99.73%Couleur et forme :SolidMasse moléculaire :477.99BPDBA
CAS :BPDBA is an effective, selective, and non-competitive inhibitor of the betaine/GABA transporter (BGT-1), displaying inhibitory activity against human BGT-1 andFormule :C19H20Cl2N2ODegré de pureté :99.43% - 99.95%Couleur et forme :SolidMasse moléculaire :363.28Ru-32514
CAS :Ru-32514 is a benzodiazepine receptor agonist.Formule :C18H17N3O2Degré de pureté :99.21%Couleur et forme :SolidMasse moléculaire :307.35Riluzole hydrochloride
CAS :Riluzole hydrochloride, an anticonvulsant Na+ channel blocker, inhibits GABA uptake (IC50: 43 µM).Formule :C8H6ClF3N2OSDegré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :270.66Lirequinil
CAS :Lirequinil (Ro 41-3696) is a small molecule GABAA receptor agonist used to study neurological disorders.Formule :C26H25ClN2O3Degré de pureté :98.54%Couleur et forme :SolidMasse moléculaire :448.94Saripidem
CAS :Saripidem (SL-85.0274) is a compound with anxiolytic activity.Formule :C19H20ClN3ODegré de pureté :98.42%Couleur et forme :SolidMasse moléculaire :341.83Golexanolone
CAS :Golexanolone can be used to study neurological diseases.Formule :C21H31NO2Degré de pureté :99.90% - 99.99%Couleur et forme :SolidMasse moléculaire :329.48Muscimol HBr
CAS :Muscimol HBr (Agarin HBr) is an agonist of GABAA receptor.Formule :C4H7BrN2O2Degré de pureté :98.13%Couleur et forme :Off-White PowderMasse moléculaire :195.01Ref: TM-T20657
1mg119,00€2mg172,00€5mg253,00€10mg406,00€25mg657,00€50mg948,00€100mg1.264,00€500mg2.555,00€1mL*10mM (DMSO)215,00€NS-2710
CAS :NS-2710, a GABA receptor agonist, is used potentially for the treatment of anxiety.Formule :C22H20N4ODegré de pureté :99.7% - 99.82%Couleur et forme :SolidMasse moléculaire :356.42Progabide
CAS :Progabide (SL 76002) is an agonist of the gamma-aminobutyric acid receptor.Formule :C17H16ClFN2O2Degré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :334.77Cirsimaritin
CAS :<p>Cirsimaritin has anti-bacterial, anti-inflammatory, anti-tumor, antioxidant effects, and protects kidneys; it weakly targets GABAA receptors.</p>Formule :C17H14O6Degré de pureté :99.9%Couleur et forme :SolidMasse moléculaire :314.29U 89843A
CAS :U 89843A is a positive allosteric modulator of gamma-aminobutyric acid (GABA)A receptors.Formule :C16H23N5Degré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :285.39CGP-54626 free base
CAS :CGP-54626 is a selective antagonist of the GABAB receptor (IC50 = 4 nM ).Formule :C18H28Cl2NO3PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :408.3CGP 64213
CAS :CGP 64213 is a GABAb receptor agonist.Formule :C26H36IN2O7PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :646.45Afizagabar
CAS :Afizagabar, a first-in-class α5-GABAAR antagonist, IC50: 585 nM, Ki: 66 nM, may boost memory.Formule :C19H12FN3O2SCouleur et forme :SolidMasse moléculaire :365.38mGAT-IN-1
CAS :mGAT-IN-1 is a potent, non-selective GAT inhibitor that inhibits mGAT3 activity well (IC50: 2.5 μM, pIC50: 5.61).Formule :C28H34ClN3O2S2Couleur et forme :SolidMasse moléculaire :544.17Adipiplon
CAS :Adipiplon(NG2-73, NG273) is a novel selective gamma-aminobutyric acid (GABA) partial agonist.Formule :C18H18FN7Couleur et forme :SolidMasse moléculaire :351.38(+)-Bicuculline methiodide
CAS :(+)-Bicuculline methiodide is a GABAA receptor blocker that blocks epileptogens and may be used in the study of neurological disorders.Formule :C21H20INO6Degré de pureté :99.24%Couleur et forme :SolidMasse moléculaire :509.29CGP 54626 hydrochloride
CAS :CGP 54626 hydrochloride is a GABAB receptor antagonist.Formule :C18H29Cl3NO3PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :444.76GMA-839
CAS :GMA-839 is a selective modulator of gamma-aminobutyric acid(A) receptors.Formule :C21H31F3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :388.46PZ-II-029
CAS :PZ-II-029 is a modulator of α6β3γ2-selective GABAA channel.Formule :C18H15N3O3Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :321.33Ref: TM-T28479
1mg52,00€5mg111,00€10mg170,00€25mg305,00€50mg472,00€100mg723,00€500mg1.454,00€1mL*10mM (DMSO)202,00€FGIN-1-27
CAS :FGIN-1-27 is a high-affinity agonist of the translocator protein and a specific peripheral benzodiazepine receptor (PBR) ligand(Ki = 5.0 nM).Formule :C28H37FN2ODegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :436.6PHP 501 trifluoroacetate
CAS :GABAA antagonistFormule :C20H21N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :319.4ADX71441
CAS :ADX71441, a GABAB PAM, lengthens urinary latencies, lessens events & volume, and may aid in alcoholism and bladder pain.Formule :C19H15ClF2N4O4Couleur et forme :SolidMasse moléculaire :436.8SCS
CAS :SCS is a GABAA receptor antagonist.Formule :C14H12N2O3Degré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :256.26L 663581
CAS :L 663581 is the benzodiazepine receptor partial agonist.Formule :C17H16ClN5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :357.79Piperidine-4-sulfonic acid
CAS :Piperidine-4-sulfonic acid is a potent GABA agonist, demonstrating an IC50 value of 0.034 μM for the inhibition of H-GABA binding [1].Formule :C5H11NO3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :165.21(-)-Bicuculline methochloride
CAS :<p>(-)-Bicuculline methochloride is a potent antagonist of GABAA receptor.</p>Formule :C21H20ClNO6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :417.84CGP36216 hydrochloride
CAS :CGP36216 hydrochloride acts as a selective antagonist at the presynaptic GABA receptor, specifically binding to the GABAB receptor with a Ki value of 0.3 μM. This compound is leveraged in research focused on anxiety and trauma-related disorders [1] [2].Formule :C5H15ClNO2PCouleur et forme :SolidMasse moléculaire :187.6Diproqualone
CAS :Diproqualone, analogous to methaqualone, exhibits sedative, anxiolytic, anti-inflammatory, and analgesic properties [1].Formule :C12H14N2O3Couleur et forme :SolidMasse moléculaire :234.255CGP 55845 hydrochloride
CAS :CGP55845 hydrochloride is a potent and selective GABAB receptor antagonist with an IC 50 of 6 nM which can be used in neurological research [1] [2].Formule :C18H23Cl3NO3PCouleur et forme :SolidMasse moléculaire :438.71GABAA receptor agent 2 TFA
CAS :Potent GABAA antagonist; IC50: 24 nM (α1β2γ2), Ki: 28 nM (rat); inactive on human GABA transporters.Formule :C22H22F3N3O3Couleur et forme :SolidMasse moléculaire :433.42NO-711ME
CAS :NO-711ME (N-O711 Methyl ester) is a prodrug of NO-711. It also is a potent and selective GABA uptake inhibitor.Formule :C22H24N2O3Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :364.44Ref: TM-T24540
1mg67,00€5mg136,00€10mg198,00€25mg316,00€50mg452,00€100mg607,00€200mg810,00€1mL*10mM (DMSO)145,00€NCS-382 sodium
CAS :NCS-382 (sodium) is a potent antagonist of the GABA receptor, exhibiting anti-sedative and anti-hypnotic properties, with applications in neurological diseaseFormule :C13H13NaO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :240.23L-822179
CAS :L-822179 (α5IA) is a selective inverse agonist for the Α5 subtype of GABAA receptor with higher intrinsic activity at the A5 subtype than other drugs.Formule :C17H14N8O2Degré de pureté :98.5% - 99.61%Couleur et forme :SolidMasse moléculaire :362.35CP-409092
CAS :<p>CP-409092 is a partial GABAA receptor agonist. It has anti-anxiety activity.</p>Formule :C17H19N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :297.35COR659
CAS :COR659: suppresses alcohol/chocolate intake in rats; enhances GABAB receptor, blocks CB1 receptor.Formule :C16H16ClNO3SDegré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :337.82Ref: TM-T36520
1mg40,00€5mg90,00€10mg130,00€25mg227,00€50mg316,00€100mg434,00€200mg590,00€1mL*10mM (DMSO)89,00€Org-21465
CAS :Org-21465, a gamma-aminobutyric acid (GABA) receptor agonist, is used potentially for the use of anesthesia.Formule :C27H43NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :445.63(R)-4-Amino-3-hydroxybutyric Acid
CAS :(R)-4-Amino-3-hydroxybutyric acid, also known as (R)-GABOB, acts as a modulator of GABA receptors, specifically binding to both GABAA and GABAB receptors and blocking GABA reuptake in rat brain synaptosomes. Additionally, it serves as a GABAC receptor agonist, triggering currents in patch-clamp assays with Xenopus oocytes that express the human receptor. In vivo studies reveal its capability to suppress electrical discharges in the amygdala in cats undergoing N-amidinobenzamide-triggered seizures, indicating its potential therapeutic application in managing seizure disorders.Formule :C4H9NO3Couleur et forme :SolidMasse moléculaire :119.12mGAT3/4-IN-2
CAS :mGAT3/4-IN-2 are potent inhibitors of mGAT3/mGAT4 with their pIC50 values of 5.44 and 5.25, respectively.Formule :C26H32ClN3OS2Couleur et forme :SolidMasse moléculaire :502.13JM-1232
CAS :JM-1232 is a sedative and hypnotic drug being researched as a potential anesthetic.Formule :C24H27N3O2Couleur et forme :SolidMasse moléculaire :389.49RPC425 free base
CAS :RPC425 is a noncompetitive inhibitors of the Betaine-γ-Aminobutyric Acid Transporter 1 (BGT1).Formule :C22H27NO2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :401.59GABA-IN-2
CAS :GABA-IN-2 (Compound 5), a GABA inhibitor, exhibits both larvicidal and insecticidal properties, achieving an 87% mortality rate at a concentration of 50 mg/L [1Formule :C12H4Cl2F6N4SeCouleur et forme :SolidMasse moléculaire :468.04TPA 023
CAS :<p>TPA 023 is a selective agonist of GABAA α2/α3 subtype (Kis = 0.19 - 0.41 nM).</p>Formule :C20H22FN7ODegré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :395.43CGP 55845
CAS :CGP 55845: potent, selective GABAB blocker, IC50=5 nM, hinders agonist binding, reduces GABA/glutamate release.Formule :C18H22Cl2NO3PCouleur et forme :SolidMasse moléculaire :402.256,2'-Dihydroxyflavone
CAS :6,2'-Dihydroxyflavone is a novel antagonist of GABAA receptor.Formule :C15H10O4Degré de pureté :99.44% - 99.67%Couleur et forme :SolidMasse moléculaire :254.24GABA-IN-4
CAS :GABA-IN-4 (Compound 17) is a derivative of N-(indol-3-ylglyoxylyl)benzylamine. It exhibits high affinity for the benzodiazepine receptor (BzR), the binding site within the GABAA receptor complex, with a Ki value of 67 nM. Benzodiazepines are widely used as anxiolytic, sedative-hypnotic, and anticonvulsant agents.Formule :C17H13ClN2O2Couleur et forme :SolidMasse moléculaire :312.75S-8510 phosphate
CAS :S-8510 phosphate is an agonist of inverse Benzodiazepine (BDZ) receptor(Kis of 34.6 nM, 36.2 nM for –GABA and +GABA respectively).Formule :C12H13N4O6PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :340.23EF1502 free base
CAS :EF1502 is a potent and selective GABA transporter inhibitor.Formule :C22H26N2O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :414.58Tuclazepam
CAS :Tuclazepam (KC 1956) is a derivative of the benzodiazepine class of drugs, exhibiting anti-anxiety and sedative properties.Formule :C17H16Cl2N2OCouleur et forme :SolidMasse moléculaire :335.23Refisolone
CAS :Refisolone is an antagonist of the GABAA receptor.Formule :C18H24O3Masse moléculaire :288.381Gabaculine HCl
CAS :Gabaculine, an irreversible GABA-T inhibitor (Ki: 2.9 μM), impacts plastid development and affects DPOR/GluTR levels.Formule :C7H10ClNO2Couleur et forme :SolidMasse moléculaire :175.61SGE-516
CAS :SGE516: neuroactive steroid, enhances GABAA, lowers neuronal activity, protects from seizures.Formule :C23H35N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :385.54CGS-9895
CAS :CGS-9895 is a GABA antagonist that operates by interacting with the benzodiazepine binding site on GABA receptors containing the γ subunit (ag).Formule :C17H13N3O2Masse moléculaire :291.304GABAA receptor agonist 2
Compound 4c, a potent GABAA agonist with anti-depressive effects in mouse FST/TST, shows promise in depression research.Formule :C22H36O5Couleur et forme :SolidMasse moléculaire :380.52β-CCM
CAS :β-CCM is a benzodiazepine receptor inverse agonist with anxiogenic and convulsant effects. It enhances emotional reactivity and reduces interference sensitivity in spatial working memory tasks. β-CCM is applicable in research related to anxiety disorders.Formule :C13H10N2O2Masse moléculaire :226.231Moxetomidate
CAS :<p>Moxetomidate is a GABAA receptor (GABAA receptor) agonist with hypnotic properties.</p>Formule :C15H18N2O3Couleur et forme :SolidMasse moléculaire :274.315GABAA receptor agonist 1
Compound 3e, a potent GABAA agonist, targets GABA sites and has potential anti-depressive effects in mice.Formule :C20H30O3Couleur et forme :SolidMasse moléculaire :318.45ZK 93426 hydrochloride
CAS :benzodiazepine receptor antagonist,competitiveFormule :C18H21ClN2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :348.82TP003
CAS :<p>TP003 is a novel non-selective GABAA receptor benzodiazepine site agonist with affinity for α1β2gam2, α2β3gam2, α3β3gam2, α5β2gam2, EC50 of 20.3, 10.6, 3.24, 5.</p>Formule :C23H16F3N3ODegré de pureté :99.17%Couleur et forme :SolidMasse moléculaire :407.39BGT1-IN-1
CAS :BGT1-IN-1 (compound 9) is an effective inhibitor of BGT1, demonstrating IC50 values of 13.9 µM for hBGT1 and 58.3 µM for GAT3. It exhibits no cytotoxic effects and possesses neuroprotective activity.Formule :C6H9NO2Couleur et forme :SolidMasse moléculaire :127.14Cyproflanilide
CAS :Cyproflanilide is a GABAR antagonist that exhibits high activity against a variety of pests, including those from the Lepidoptera, Coleoptera, and Thysanoptera orders.Formule :C28H17BrF12N2O2Couleur et forme :SolidMasse moléculaire :721.33Thiomuscimol hydrobromide
CAS :Thiomuscimol hydrobromide is an agonist of GABAA receptor.Formule :C4H6N2OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :130.17Fletazepam
CAS :Fletazepam, a benzodiazepine derivative, exhibits sedative, anti-anxiety, and muscle-relaxant properties. It is utilized in neurological research.Formule :C17H13ClF4N2Couleur et forme :SolidMasse moléculaire :356.74(-)-Bicuculline methobromide
CAS :(-)-Bicuculline methobromide is a potent antagonist of GABAA receptor .Formule :C21H20BrNO6Couleur et forme :WhiteMasse moléculaire :462.29Alfadolone acetate
CAS :Alfadolone acetate is a gamma-aminobutyric acid (GABA) receptor agonist.Formule :C23H34O5Couleur et forme :SolidMasse moléculaire :390.512-AEMP TFA
CAS :2-AEMP TFA is a potent and rapidly acting antagonist of GABA(A)-ρ1 receptors. 2-AEMP is an analog of GABA.Formule :C3H10NO3PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :139.0913-Methylglutaconic acid
CAS :3-Methylglutaconic acid, a primary metabolite accumulating in 3-Methylglutaconic aciduria (MGTA), induces lipid and protein oxidation, while diminishing non-enzymatic antioxidant defenses in cerebral cortex supernatants, thereby promoting oxidative stress in the cerebral cortex. This compound is utilized in research concerning brain damage diseases [1].Formule :C6H8O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :144.13CGP 44532
CAS :CGP 44532 a GABAB receptor agonist.Formule :C4H12NO3PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :153.12Pipequaline
CAS :Pipequaline (PK-8165) is an anticonflict & anticonvulsant quinoline derivative. It is an anxiolytic drug that was never marketed. It possesses a novel chemical structure that is not closely related to other drugs of this type. The drug has a similar pharmacological profile to the benzodiazepine family of drugs, but with mainly anxiolytic properties and very little sedative, amnestic or anticonvulsant effects, and so is classified as a nonbenzodiazepine anxiolytic.Formule :C22H24N2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :316.44Pazinaclone
CAS :Pazinaclone is a non-benzodiazepine (GABAA) partial agonist with sedative and anxiolytic activity.Formule :C25H23ClN4O4Degré de pureté :97.79% - 98.65%Couleur et forme :SolidMasse moléculaire :478.93Xilmenolone
CAS :<p>Xilmenolone acts as a positive allosteric modulator of the GABA_A receptor [1].</p>Formule :C26H37N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :423.59CGP 56999A
CAS :CGP 56999A is a GABA(B) receptor antagonist; it boosts BDNF and reduces dopamine loss in rat striatum.Formule :C19H30NO5PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :383.42
