Récepteur GABA
Les récepteurs GABA sont les principaux récepteurs de neurotransmetteurs inhibiteurs du système nerveux central, jouant un rôle crucial dans la régulation de l'excitabilité neuronale et le maintien de l'équilibre entre excitation et inhibition. La dysfonction des récepteurs GABA est impliquée dans divers troubles neurologiques et psychiatriques, notamment l'épilepsie, l'anxiété et la dépression. Chez CymitQuimica, nous proposons une gamme complète de modulateurs des récepteurs GABA pour soutenir vos recherches en neurobiologie, santé mentale et développement thérapeutique.
336 produits trouvés pour "Récepteur GABA"
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Furosemide sodium
CAS :<p>Furosemide sodium: potent NKCC inhibitor, loop diuretic, treats heart failure, hypertension, edema, selective GABAA antagonist.</p>Formule :C12H10ClN2NaO5SDegré de pureté :99.52% - >99.99%Couleur et forme :SolidMasse moléculaire :352.73Withasomniferolide B
CAS :<p>Withasomniferolide B, a withanolide from Withania somnifera root, activates GABAA receptors.</p>Formule :C28H36O4Couleur et forme :SolidMasse moléculaire :436.58Neurotransmitter Receptor Compound Library
<p>A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening；</p>Couleur et forme :Odour SolidCGP 35348
CAS :<p>CGP 35348 是 GABAB 受体的选择性拮抗剂 (EC50 = 34 μM)。 CGP 35348 可用于研究白化新生小鼠脑损伤后的神经肌肉协调和空间学习。</p>Formule :C8H20NO4PDegré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :225.22Antidepressant agent 3
<p>Agent 3: orally active, antidepressant, anxiolytic, boosts performance and cognition.</p>Formule :C17H30ClN5O2SCouleur et forme :SolidMasse moléculaire :403.97Endosulfan I
CAS :<p>Endosulfan I is one of the two major stereoisomers of the broad-spectrum insecticide Endosulfan inhibi the GABA/benzodiazepine/picrotoxin complex</p>Formule :C9H6Cl6O3SDegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :406.93Ion Channel Targeted Library
<p>A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;</p>Couleur et forme :Odour SolidAnticonvulsant agent 9
<p>Anticonvulsant agent 9 (compound 4f) is an activator of the α1β2γ2GABA_A receptor, with an EC50 value of 1.24 μM. It inhibits the inactivation of Nav1.2 channels and exhibits significant anticonvulsant activity.</p>Formule :C22H24N4O2Couleur et forme :SolidMasse moléculaire :376.45Nipecotic acid
CAS :<p>Compound PDK0243, with CAS No. 498-95-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0243 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Formule :C6H11NO2Couleur et forme :Off-White To Pale Yellow-Beige PowderMasse moléculaire :129.16α-Casozepine
CAS :<p>α-Casozepine,Bioactive peptide from milk α-S1 casein. Binds GABA receptors. Anti-anxiety effects.</p>Formule :C60H94N14O16Couleur et forme :SolidMasse moléculaire :1267.47Atagabalin
CAS :<p>Atagabalin (PD 0200390), a gabamimetic for insomnia treatment and related to gabapentin, was halted due to poor trial outcomes.</p>Formule :C10H19NO2Couleur et forme :SolidMasse moléculaire :185.26Brexanolone caprilcerbate
CAS :<p>Brexanolone caprilcerbate is an effective positive allosteric modulator of the GABAA receptor.</p>Formule :C48H78O12Couleur et forme :SolidMasse moléculaire :847.13Inaperisone
CAS :<p>Inaperisone: a novel muscle relaxant that indirectly inhibits voiding reflex via brainstem GABAB receptors.</p>Formule :C16H23NODegré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :245.36MIDD0301
CAS :<p>MIDD0301 is a potent positive allosteric α5β3γ selective GABAA receptor (GABAAR) ligand with EC50 of 17 nM.</p>Formule :C19H13BrFN3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :414.233-Aminopropylphosphonic Acid
CAS :<p>3-aminopropylphosphonic acid (3-APPA) is a phosphonic analog of GABA that acts as a partial agonist of GABAB receptors (IC50 = 1.5 μM in a radioligand binding</p>Formule :C3H10NO3PDegré de pureté :99.84%Couleur et forme :Light Yellow LiquidMasse moléculaire :139.09epi-Aszonalenin A
CAS :<p>epi-Aszonalenin A: a psychoactive benzodiazepine from Aspergillus novofumigatus.</p>Formule :C25H25N3O3Couleur et forme :SolidMasse moléculaire :415.48Cinazepam
CAS :<p>Cinazepam is a GABAA receptor partial agonist and a benzodiazepine derivative with anxiolytic and sedative properties. Cinazepam can be utilized in research related to sleep disorders.</p>Formule :C19H14BrClN2O5Couleur et forme :SolidMasse moléculaire :465.68GABAA receptor modulator-4
<p>GABAA receptor modulator-4 (Compound 4) acts as a negative allosteric modulator of the GABAA receptor. It inhibits the peak and steady-state currents mediated by the α1β3γ2 GABAA receptors, with an IC50 of 10 μM for both.</p>Formule :C15H17BrO4SCouleur et forme :SolidMasse moléculaire :373.26GABAA receptor modulator-3
<p>GABAA receptor modulator-3 (compound 3b) is a positive allosteric modulator (PAM). It inhibits the peak current and steady-state current of α1β3γ2 GABAAR with IC50 values of 671 μM and 64 μM, respectively.</p>Formule :C18H22O2Couleur et forme :SolidMasse moléculaire :270.37FGIN-1-43
CAS :<p>FGIN-1-43 is a potent and specific ligand for the mitochondrial DBI receptor.</p>Formule :C28H36Cl2N2ODegré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :487.56,7-dimethylisatin
CAS :<p>6,7-Dimethylisatin (6,7-dimethyl-1H-indole-2,3-dione) inhibits hGAT3 with IC50 of 108 μM. 6,7-Dimethylisatin also inhibits hBGT1, hGAT2.</p>Formule :C10H9NO2Degré de pureté :98.98%Couleur et forme :SolidMasse moléculaire :175.1812,14-Dichlorodehydroabietic acid
CAS :<p>12,14-Dichlorodehydroabietic acid activates BK channels, blocks GABA A receptors, and increases calcium and neurotransmitter release.</p>Formule :C20H26Cl2O2Couleur et forme :SolidMasse moléculaire :369.33Fipronil sulfone
CAS :<p>Fipronil sulfone is an insecticide fipronil. Its metabolite fipronil sulphone is an inhibitor of rat ɑ1β2γ2L GABA(A) receptor.</p>Formule :C12H4Cl2F6N4O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :453.14Chrodrimanin B
CAS :<p>Chrodrimanin B is a useful organic compound for research related to life sciences. The catalog number is T126052 and the CAS number is 132196-54-4.</p>Formule :C27H32O8Couleur et forme :SolidMasse moléculaire :484.545(Iso)-Atagabalin HCl
CAS :<p>(Iso)-Atagabalin HCl(isomer-Atagabalin HCl) is an alpha -2- delta ligand that can be used to treat non-restorative sleep.</p>Formule :C10H20ClNO2Degré de pureté :99.26% - >99.99%Couleur et forme :SoildMasse moléculaire :221.72Riluzole-13C,15N2
CAS :<p>Riluzole-13C,15N2 (PK 26124-13C,15N2) is a 13C and 15N labeled form of Riluzole, a glutamate antagonist with anticonvulsant activity, inhibiting GABA uptake.</p>Formule :CC7H5F3OS15N2Couleur et forme :SolidMasse moléculaire :237.18Lesogaberan napadisylate
CAS :<p>Lesogaberan (AZD-3355) is a selective GABAB agonist with EC50 of 8.6 nM, Ki of 5.1 nM in rats, and acts peripherally on the esophageal sphincter.</p>Formule :C13H17FNO5PSCouleur et forme :SolidMasse moléculaire :349.31GABA-A Receptor Ligand-1
<p>GABA-A Receptor Ligand-1 (Compound 4) is a ligand for the GABA-A receptor with a pKi of 7.27. It alleviates mitochondrial dysfunction, promotes neurite outgrowth and neuronal regeneration, and demonstrates neuroprotective effects in a rat ischemic stroke model.</p>Formule :C20H20FN3OCouleur et forme :SolidMasse moléculaire :337.391Furosemide
CAS :<p>Furosemide is a potent NKCC2 (Na-K-2Cl symporter) inhibitor, used for edema and chronic renal insufficiency.</p>Formule :C12H11ClN2O5SDegré de pureté :99.32% - 99.89%Couleur et forme :Crystals From Aqueous Ethanol Tasteless (Ntp 1992)Masse moléculaire :330.744RuBi-GABA
CAS :<p>Ruthenium-bipyridine-triphenylphosphine caged GABA</p>Formule :C42H39F6N5O2P2RuDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :922.8(1S,3R)-3-Aminocyclopentane carboxylic acid
CAS :<p>(1S,3R)-3-Aminocyclopentane carboxylic acid exhibits activity on GABAA receptors.</p>Formule :C6H11NO2Couleur et forme :SolidMasse moléculaire :129.16Etifoxine
CAS :<p>Etifoxine targets β2/β3 GABAA receptors, is anxiolytic in humans/rodents, boosts GABAA, binds TSPO, aids axon regeneration, no sedative effects.</p>Formule :C17H17ClN2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :300.78Padsevonil
CAS :<p>Padsevonil (UCB-0942) is a potential GABA A receptor orthosteric modulator with antiepileptic activity for the treatment of epilepsy.</p>Formule :C14H14ClF5N4O2SDegré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :432.80MRK-016
CAS :<p>MRK-016 is a selective GABAA α5 receptor inverse agonist/ negative allosteric modulator, orally available and penetrating the BBB. MRK-016 is antidepressant.</p>Formule :C17H20N8O2Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :368.39Propanidid
CAS :<p>Propanidid (Sombrevin) is a gamma-aminobutyric acid type A receptor (GABAA) agonist and an intravenous anesthetic that lowers arterial blood pressure.</p>Formule :C18H27NO5Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :337.41TACA
CAS :<p>GABAA agonist</p>Formule :C4H7NO2Degré de pureté :98%Couleur et forme :White SolidMasse moléculaire :101.1Valnoctamide
CAS :<p>Valnoctamide (Valmethamide) has antiepileptic and anticonvulsant activity and may be used in the study of neurological disorders.</p>Formule :C8H17NODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :143.23Vigabatrin Hydrochloride
CAS :<p>Vigabatrin Hydrochloride (γ-Vinyl-GABA hydrochloride) is a structural analog of the GABA, irreversibly inhibiting the catabolism of GABA by GABA transaminase.</p>Formule :C6H11NO2·HClDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :165.62Dipropofol
CAS :<p>Dipropofol (4,4-Bis(2,6-di-isopropylphenol)) is a small molecule GABAA receptor agonist that can be used to study epilepsy.</p>Formule :C24H34O2Degré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :354.53L-655708
CAS :<p>L-655708 is a selective and highly potent GABAA receptor reverse agonist with a Ki value of 0.45 nM.</p>Formule :C18H19N3O4Degré de pureté :98.41%Couleur et forme :PowderMasse moléculaire :341.36CGP 36742
CAS :<p>CGP 36742 blocks GABAB receptor, crosses blood-brain barrier, aids depression treatment (IC50: 32 μM).</p>Formule :C7H18NO2PCouleur et forme :SolidMasse moléculaire :179.2(-)-α-Pinene
CAS :<p>(-)-α-Pinene ((1S)-(-)-Alpha-Pinene) enhances the quantity of NREMS without affecting the intensity of NREMS by prolonging GABAergic synaptic transmission,</p>Formule :C10H16Degré de pureté :98.02% - 98.60%Couleur et forme :Colourless LiquidMasse moléculaire :136.23Furosemide-d5
CAS :<p>Furosemide-d5 is a deuterium marker for Furosemide and used in isotope tracer experiments. orally active inhibitor of Na+/K+/2Cl- (NKCC) diuretic reagent.</p>Formule :C12H11ClN2O5SCouleur et forme :SolidMasse moléculaire :335.78Ocinaplon
CAS :<p>Ocinaplon (DOV 273547) is a GABAA receptors modulator.</p>Formule :C17H11N5ODegré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :301.3Isoflurane
CAS :<p>Isoflurane (Forane) is a stable, non-explosive inhalation anesthetic that has been reported to induce caspase-3 activation.</p>Formule :C3H2ClF5ODegré de pureté :98%Couleur et forme :Clear Colorless Liquid LiquidMasse moléculaire :184.49Ginkgolide A
CAS :<p>Ginkgolide A (BN-52020), from Ginkgo biloba leaves, is an active PAF antagonist with potential in treating inflammation and immune disorders.</p>Formule :C20H24O9Degré de pureté :98.76% - 99.81%Couleur et forme :White PowderMasse moléculaire :408.4Imidazenil
CAS :<p>Imidazenil is an modulator of GABA-A that blocks the sedative effects without lowering the convulsion threshold.</p>Formule :C18H12BrFN4ODegré de pureté :98.4%Couleur et forme :SolidMasse moléculaire :399.22γ-Acetylenic GABA
CAS :<p>γ-Acetylenic GABA (4-Aminohex-5-ynoic acid) is a potent, irreversible inhibitor of GABA-transaminase.</p>Formule :C6H9NO2Couleur et forme :SolidMasse moléculaire :127.1434-Acetamidobutanoic acid
CAS :<p>4-Acetamidobutanoic acid, a GABA derivative in eukaryotes, found in blood, feces, urine, and human prostate.</p>Formule :C6H11NO3Degré de pureté :98.51%Couleur et forme :SolidMasse moléculaire :145.16(R)-baclofen
CAS :<p>(R)-baclofen (STX209), a derivative of gamma-aminobutyric acid, is commonly utilized for the treatment of spasticity.</p>Formule :C10H12ClNO2Degré de pureté :97.20% - 98.94%Couleur et forme :SolidMasse moléculaire :213.66
