Récepteur GABA
Les récepteurs GABA sont les principaux récepteurs de neurotransmetteurs inhibiteurs du système nerveux central, jouant un rôle crucial dans la régulation de l'excitabilité neuronale et le maintien de l'équilibre entre excitation et inhibition. La dysfonction des récepteurs GABA est impliquée dans divers troubles neurologiques et psychiatriques, notamment l'épilepsie, l'anxiété et la dépression. Chez CymitQuimica, nous proposons une gamme complète de modulateurs des récepteurs GABA pour soutenir vos recherches en neurobiologie, santé mentale et développement thérapeutique.
371 produits trouvés pour "Récepteur GABA"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
Azocarnil
Azocarnil is a GABAergic agonist-enhancer used in neurological system research.Couleur et forme :Odour SolidGAD65(247-266) epitope TFA
GAD65(247-266) epitope TFA, a T cell epitope derived from islet antigens, exhibits competitive binding to the type I diabetes-associated molecule I-A g7, albeitFormule :C111H174F3N27O29S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2535.99AHN-683
CAS :AHN-683 is a fluorescent ligand. It was used for peripheral-type benzodiazepine receptors.Formule :C42H32FN3O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :709.72MmTx1 toxin
Micrurotoxin 1 (MmTx1 toxin) acts as an allosteric modulator of GABA A receptors, enhancing the receptor's sensitivity to its agonist [1].Formule :C295H455N95O97S10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :7205Brexanolone caprilcerbate
CAS :Brexanolone caprilcerbate is an effective positive allosteric modulator of the GABAA receptor.Formule :C48H78O12Couleur et forme :SolidMasse moléculaire :847.13(1S,3R)-3-Aminocyclopentane carboxylic acid
CAS :(1S,3R)-3-Aminocyclopentane carboxylic acid exhibits activity on GABAA receptors.Formule :C6H11NO2Couleur et forme :SolidMasse moléculaire :129.16Ion Channel Targeted Library
A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;
Couleur et forme :Odour SolidWithasomniferolide B
CAS :Withasomniferolide B, a withanolide from Withania somnifera root, activates GABAA receptors.Formule :C28H36O4Couleur et forme :SolidMasse moléculaire :436.58GABA receptor Antagonist 1
GABA receptor Antagonist 1 (compound 7w) effectively inhibits the Px RDL1 GABAR at an IC50 of 7.08 nmol/L and demonstrates insecticidal efficacy against P.Degré de pureté :98%Couleur et forme :Odour SolidGABOB (β-hydroxy-GABA)
CAS :GABOB, an epilepsy treatment, is GABA's analogue and may act as a neurotransmitter.Formule :C4H9NO3Couleur et forme :White To Light Yellow Crystal PowderMasse moléculaire :119.12Emamectin B1a
CAS :Emamectin B1a can be used in relevant research in the life sciences. Its product number is T37663 and CAS number is 121124-29-6.
Formule :C49H75NO13Couleur et forme :SolidMasse moléculaire :886.133Cinazepam
CAS :Cinazepam is a GABAA receptor partial agonist and a benzodiazepine derivative with anxiolytic and sedative properties. Cinazepam can be utilized in research related to sleep disorders.Formule :C19H14BrClN2O5Couleur et forme :SolidMasse moléculaire :465.68Pikamilone Sodium
CAS :Pikamilone Sodium is a prodrug of GABA used for therapy of neurogenic bladder in spinal and benign prostatic hyperplasia.Formule :C10H11N2NaO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :230.2Furosemide
CAS :Furosemide is a potent NKCC2 (Na-K-2Cl symporter) inhibitor, used for edema and chronic renal insufficiency.Formule :C12H11ClN2O5SDegré de pureté :99.32% - 99.89%Couleur et forme :Crystals From Aqueous Ethanol Tasteless (Ntp 1992)Masse moléculaire :330.744GABA-A Receptor Ligand-1
GABA-A Receptor Ligand-1 (Compound 4) is a ligand for the GABA-A receptor with a pKi of 7.27. It alleviates mitochondrial dysfunction, promotes neurite outgrowth and neuronal regeneration, and demonstrates neuroprotective effects in a rat ischemic stroke model.Formule :C20H20FN3OCouleur et forme :SolidMasse moléculaire :337.39112,14-Dichlorodehydroabietic acid
CAS :12,14-Dichlorodehydroabietic acid activates BK channels, blocks GABA A receptors, and increases calcium and neurotransmitter release.Formule :C20H26Cl2O2Couleur et forme :SolidMasse moléculaire :369.333-Aminopropylphosphonic Acid
CAS :3-aminopropylphosphonic acid (3-APPA) is a phosphonic analog of GABA that acts as a partial agonist of GABAB receptors (IC50 = 1.5 μM in a radioligand binding
Formule :C3H10NO3PDegré de pureté :99.84%Couleur et forme :Light Yellow LiquidMasse moléculaire :139.09Desalkylgidazepam
CAS :Desalkylgidazepam, a benzodiazepine compound, is a metabolite of gidazepam. It is capable of activating both GABA A-type receptors and the translocator protein (TSPO).Formule :C15H11BrN2OCouleur et forme :SolidMasse moléculaire :315.173-(4-Chlorophenyl)-4-hydroxybutyric Acid (sodium salt)
CAS :3-(4-Chlorophenyl)-4-hydroxybutyric Acid (sodium salt) can be used in related research in the field of life sciences.Formule :C10H10ClNaO3Couleur et forme :SolidMasse moléculaire :236.63S-8510 free base
CAS :S-8510 is a GABA-A receptor inverse agonist enhancing memory, LTP, and neurotransmitters in rats.Formule :C12H10N4O2Couleur et forme :SolidMasse moléculaire :242.23GABA-IN-1
GABA-IN-1 (Compound 6), a GABA inhibitor, exhibits larvicidal and insecticidal properties, achieving a mortality rate of 93% at a concentration of 50 mg/L [1].Couleur et forme :Odour SolidFipronil sulfone
CAS :Fipronil sulfone is an insecticide fipronil. Its metabolite fipronil sulphone is an inhibitor of rat ɑ1β2γ2L GABA(A) receptor.Formule :C12H4Cl2F6N4O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :453.14Chrodrimanin B
CAS :Chrodrimanin B is a useful organic compound for research related to life sciences. The catalog number is T126052 and the CAS number is 132196-54-4.Formule :C27H32O8Couleur et forme :SolidMasse moléculaire :484.545MIDD0301
CAS :MIDD0301 is a potent positive allosteric α5β3γ selective GABAA receptor (GABAAR) ligand with EC50 of 17 nM.
Formule :C19H13BrFN3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :414.23Lesogaberan napadisylate
CAS :Lesogaberan (AZD-3355) is a selective GABAB agonist with EC50 of 8.6 nM, Ki of 5.1 nM in rats, and acts peripherally on the esophageal sphincter.Formule :C13H17FNO5PSCouleur et forme :SolidMasse moléculaire :349.31KGP-25
KGP-25 is an inhibitor of the voltage-gated sodium channel 1.8 (Nav1.8), utilized for analgesia by targeting the peripheral nervous system (PNS). Additionally, it targets the γ-aminobutyric acid subtype A receptor (GABAA) in the central nervous system (CNS) for use as a general anesthetic.Couleur et forme :Odour Solidepi-Aszonalenin A
CAS :epi-Aszonalenin A: a psychoactive benzodiazepine from Aspergillus novofumigatus.Formule :C25H25N3O3Couleur et forme :SolidMasse moléculaire :415.48γ-Acetylenic GABA hydrochloride
CAS :γ-Acetylenic GABA hydrochloride is a GABA transaminase inhibitor.Formule :C6H10ClNO2Degré de pureté :97.83% - 99.44%Couleur et forme :SolidMasse moléculaire :163.6Sandaracopimaric acid
CAS :Sandaracopimaric acid, an anti-inflammatory diterpene, relaxes pulmonary arteries with an EC50 of 43.93 μM.Formule :C20H30O2Couleur et forme :SolidMasse moléculaire :302.456,7-dimethylisatin
CAS :6,7-Dimethylisatin (6,7-dimethyl-1H-indole-2,3-dione) inhibits hGAT3 with IC50 of 108 μM. 6,7-Dimethylisatin also inhibits hBGT1, hGAT2.Formule :C10H9NO2Degré de pureté :98.98%Couleur et forme :SolidMasse moléculaire :175.18Neurotransmitter Receptor Compound Library
A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening；
Couleur et forme :Odour SolidCAY10787
CAS :CAY10787, an oxysterol, inhibits GABAA receptors (IC50s: 1-1.5μM) and lessens GABA responses in mouse DRG neurons.Formule :C27H42OCouleur et forme :SolidMasse moléculaire :382.632GABAA receptor modulator-3
GABAA receptor modulator-3 (compound 3b) is a positive allosteric modulator (PAM). It inhibits the peak current and steady-state current of α1β3γ2 GABAAR with IC50 values of 671 μM and 64 μM, respectively.Formule :C18H22O2Couleur et forme :SolidMasse moléculaire :270.37RuBi-GABA
CAS :Ruthenium-bipyridine-triphenylphosphine caged GABAFormule :C42H39F6N5O2P2RuDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :922.8CGP 35348
CAS :CGP 35348 是 GABAB 受体的选择性拮抗剂 (EC50 = 34 μM)。 CGP 35348 可用于研究白化新生小鼠脑损伤后的神经肌肉协调和空间学习。Formule :C8H20NO4PDegré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :225.22Antidepressant agent 3
Agent 3: orally active, antidepressant, anxiolytic, boosts performance and cognition.Formule :C17H30ClN5O2SCouleur et forme :SolidMasse moléculaire :403.97Riluzole-13C,15N2
CAS :Riluzole-13C,15N2 (PK 26124-13C,15N2) is a 13C and 15N labeled form of Riluzole, a glutamate antagonist with anticonvulsant activity, inhibiting GABA uptake.Formule :CC7H5F3OS15N2Couleur et forme :SolidMasse moléculaire :237.18(Iso)-Atagabalin HCl
CAS :(Iso)-Atagabalin HCl(isomer-Atagabalin HCl) is an alpha -2- delta ligand that can be used to treat non-restorative sleep.Formule :C10H20ClNO2Degré de pureté :99.88% - >99.99%Couleur et forme :SoildMasse moléculaire :221.72Furosemide sodium
CAS :Furosemide sodium: potent NKCC inhibitor, loop diuretic, treats heart failure, hypertension, edema, selective GABAA antagonist.Formule :C12H10ClN2NaO5SDegré de pureté :99.52% - >99.99%Couleur et forme :SolidMasse moléculaire :352.73Flufiprole
CAS :Flufiprole is used as a phenylpyrazole pesticide. It has enantioselective metabolism in human and rat liver microsomes.Formule :C16H10Cl2F6N4OSCouleur et forme :SolidMasse moléculaire :491.24Antidepressant agent 4
Antidepressant agent 4: orally active, has antidepressant, anxiolytic, and nootropic effects.Formule :C19H38ClN5O2SCouleur et forme :SolidMasse moléculaire :436.06Nitrazolam
CAS :Nitrazolam is a benzodiazepine compound that may exhibit central nervous system depressant properties similar to traditional benzodiazepine drugs by acting on the GABA receptors (GABA receptor). These effects include sedation, hypnosis, anxiolytic, and anticonvulsant activities.Formule :C17H13N5O2Couleur et forme :SolidMasse moléculaire :319.32GABAA receptor modulator-4
GABAA receptor modulator-4 (Compound 4) acts as a negative allosteric modulator of the GABAA receptor. It inhibits the peak and steady-state currents mediated by the α1β3γ2 GABAA receptors, with an IC50 of 10 μM for both.Formule :C15H17BrO4SCouleur et forme :SolidMasse moléculaire :373.265α-Androst-16-en-3α-ol
CAS :5α-Androst-16-en-3α-ol is a steroid pheromone that has been found in boar testes and human male axillary sweat and has diverse biological activities.1,2ItFormule :C19H30OCouleur et forme :SolidMasse moléculaire :274.448Guvacine hydrobromide
CAS :Guvacine hydrobromide, an alkaloid derived from the Areca catechu nut, serves as a potent inhibitor of GABA (GABA uptakp) uptake.Formule :C6H10BrNO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :208.05Etifoxine
CAS :Etifoxine targets β2/β3 GABAA receptors, is anxiolytic in humans/rodents, boosts GABAA, binds TSPO, aids axon regeneration, no sedative effects.Formule :C17H17ClN2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :300.78CGP 36742
CAS :CGP 36742 blocks GABAB receptor, crosses blood-brain barrier, aids depression treatment (IC50: 32 μM).Formule :C7H18NO2PCouleur et forme :SolidMasse moléculaire :179.2Valnoctamide
CAS :Valnoctamide (Valmethamide) has antiepileptic and anticonvulsant activity and may be used in the study of neurological disorders.Formule :C8H17NODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :143.23TACA
CAS :GABAA agonistFormule :C4H7NO2Degré de pureté :98%Couleur et forme :White SolidMasse moléculaire :101.1Vigabatrin Hydrochloride
CAS :Vigabatrin Hydrochloride (γ-Vinyl-GABA hydrochloride) is a structural analog of the GABA, irreversibly inhibiting the catabolism of GABA by GABA transaminase.Formule :C6H11NO2·HClDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :165.62
