Récepteur GABA
Les récepteurs GABA sont les principaux récepteurs de neurotransmetteurs inhibiteurs du système nerveux central, jouant un rôle crucial dans la régulation de l'excitabilité neuronale et le maintien de l'équilibre entre excitation et inhibition. La dysfonction des récepteurs GABA est impliquée dans divers troubles neurologiques et psychiatriques, notamment l'épilepsie, l'anxiété et la dépression. Chez CymitQuimica, nous proposons une gamme complète de modulateurs des récepteurs GABA pour soutenir vos recherches en neurobiologie, santé mentale et développement thérapeutique.
371 produits trouvés pour "Récepteur GABA"
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Propanidid
CAS :Propanidid (Sombrevin) is a gamma-aminobutyric acid type A receptor (GABAA) agonist and an intravenous anesthetic that lowers arterial blood pressure.Formule :C18H27NO5Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :337.41(-)-α-Pinene
CAS :(-)-α-Pinene ((1S)-(-)-Alpha-Pinene) enhances the quantity of NREMS without affecting the intensity of NREMS by prolonging GABAergic synaptic transmission,Formule :C10H16Degré de pureté :98.02% - 98.60%Couleur et forme :Colourless LiquidMasse moléculaire :136.23Padsevonil
CAS :Padsevonil (UCB-0942) is a potential GABA A receptor orthosteric modulator with antiepileptic activity for the treatment of epilepsy.Formule :C14H14ClF5N4O2SDegré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :432.80MRK-016
CAS :MRK-016 is a selective GABAA α5 receptor inverse agonist/ negative allosteric modulator, orally available and penetrating the BBB. MRK-016 is antidepressant.Formule :C17H20N8O2Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :368.39CGP 36742
CAS :CGP 36742 blocks GABAB receptor, crosses blood-brain barrier, aids depression treatment (IC50: 32 μM).Formule :C7H18NO2PCouleur et forme :SolidMasse moléculaire :179.2Vigabatrin Hydrochloride
CAS :Vigabatrin Hydrochloride (γ-Vinyl-GABA hydrochloride) is a structural analog of the GABA, irreversibly inhibiting the catabolism of GABA by GABA transaminase.Formule :C6H11NO2·HClDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :165.62Valnoctamide
CAS :Valnoctamide (Valmethamide) has antiepileptic and anticonvulsant activity and may be used in the study of neurological disorders.Formule :C8H17NODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :143.23DL-Menthol
CAS :DL-Menthol ((±)-Menthol) is a racemic mixture of the monoterpene alcohols (–)-menthol and (+)-menthod, which have been found in Cannabis.Formule :C10H20ODegré de pureté :99.74%Couleur et forme :White Crystals /89-78-1/ Physical Description White Crystalline Solid With A Peppermint Odor And Taste (Ntp 1992)Masse moléculaire :156.27Ocinaplon
CAS :Ocinaplon (DOV 273547) is a GABAA receptors modulator.Formule :C17H11N5ODegré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :301.3Saclofen
CAS :Saclofen is a GABA analog and GABAB receptor antagonist, useful for studying inhibitory brain signals. IC50: 7.8 μM.Formule :C9H12ClNO3SDegré de pureté :99.17%Couleur et forme :White Crystalline SolidMasse moléculaire :249.71Ref: TM-T4440
1mg52,00€5mg113,00€10mg177,00€25mg340,00€50mg550,00€100mg860,00€200mg1.161,00€1mL*10mM (DMSO)108,00€Gabazine free base
CAS :Gabazine free base is a specific antagonist of the GABA receptor. It does not affect GABA-transaminase or glutamate-decarboxylase activities.Formule :C15H17N3O3Couleur et forme :SolidMasse moléculaire :287.316-Methylflavone
CAS :6-Methylflavone is an activator of α1β2γ2L and α1β2 GABAA receptors.Formule :C16H12O2Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :236.27Imepitoin
CAS :Imepitoin (AWD 131-138), a new low-affinity partial benzodiazepine receptor agonist, shows potent anticonvulsant and anxiolytic properties in rodent models.Formule :C13H14ClN3O2Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :279.72Tiagabine hydrochloride
CAS :Tiagabine hydrochloride, a nipecotic acid derivative, is an anticonvulsant and selective GABA reuptake inhibitor.Formule :C20H25NO2S2·HClDegré de pureté :99.09% - 99.77%Couleur et forme :White To Off-White SolidMasse moléculaire :412.01(+)-Kavain
CAS :(+)-Kavain ((R)-KAWAIN) is one of the six major kavalactones found in the Piper methysticum (kava) plant; reversible inhibitor of MAO-B.Formule :C14H14O3Degré de pureté :97% - ≥95%Couleur et forme :White Fine PowderMasse moléculaire :230.26γ-Acetylenic GABA
CAS :γ-Acetylenic GABA (4-Aminohex-5-ynoic acid) is a potent, irreversible inhibitor of GABA-transaminase.Formule :C6H9NO2Couleur et forme :SolidMasse moléculaire :127.143Baclofen hydrochloride
CAS :Baclofen HCL, a GABA-B agonist, treats muscle spasticity by reducing excitatory transmission.Formule :C10H13Cl2NO2Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :250.122Thiocolchicoside
CAS :Thiocolchicoside, a muscle relaxant, has anti-inflammatory and analgesic properties; not for seizure-prone people.Formule :C27H33NO10SDegré de pureté :99.11% - 99.39%Couleur et forme :SolidMasse moléculaire :563.62(-)-Securinine
CAS :(-)-Securinine (Securinine) is plant-derived alkaloid and also a GABAA receptor antagonist.Formule :C13H15NO2Degré de pureté :99.58% - 99.87%Couleur et forme :SolidMasse moléculaire :217.26U93631
CAS :GABAA antagonist; binds picrotoxin site, stabilizes inactive channel. Speeds GABA-induced Cl- decay, minor peak effect. Inhibits 5-HT3A receptors.Formule :C17H21N3O2Degré de pureté :99.65% - 99.76%Couleur et forme :SolidMasse moléculaire :299.376-(4-Methoxyphenyl)-3-pyridazinamine
CAS :6-(4-Methoxyphenyl)-3-pyridazinamine is a GABAA receptor antagonistFormule :C11H11N3ODegré de pureté :99.03%Couleur et forme :SolidMasse moléculaire :201.22Ginkgolide A
CAS :Ginkgolide A (BN-52020), from Ginkgo biloba leaves, is an active PAF antagonist with potential in treating inflammation and immune disorders.Formule :C20H24O9Degré de pureté :98.76% - 99.81%Couleur et forme :White PowderMasse moléculaire :408.40L-838417 D9
CAS :L-838417 D9 (C-21191) is a novel deuterated subtype-selective GABAA positive allosteric modulator, acting as a partial agonist at α2, α3 and α5 subtypes[1].Formule :C19H10D9F2N7ODegré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :408.45Ref: TM-T22301
2mg34,00€5mg52,00€10mg71,00€25mg128,00€50mg200,00€100mg323,00€200mg447,00€1mL*10mM (DMSO)58,00€(R)-baclofen
CAS :(R)-baclofen (STX209), a derivative of gamma-aminobutyric acid, is commonly utilized for the treatment of spasticity.Formule :C10H12ClNO2Degré de pureté :97.20% - 98.94%Couleur et forme :SolidMasse moléculaire :213.66Arecaidine hydrochloride
CAS :Arecaidine hydrochloride may have carcinogenesis.Formule :C7H12ClNO2Degré de pureté :99.69% - ≥95%Couleur et forme :SolidMasse moléculaire :177.63Ref: TM-T5799
2mg34,00€5mg48,00€10mg67,00€25mg100,00€50mg149,00€100mg213,00€200mg316,00€1mL*10mM (DMSO)49,00€Lorediplon
CAS :Lorediplon is a novel hypnotic drug acting as a GABAA receptor modulator, differentially active at the α1-subunit, associated with promoting sleep.Formule :C20H15FN4O2SDegré de pureté :99.12% - 99.19%Couleur et forme :SolidMasse moléculaire :394.42SKF89976A HCl
CAS :SKF89976A: GABA uptake inhibitor, selective for GAT-1, passes blood-brain barrier, active in vivo (IC50: 0.13 μM hGAT-1).Formule :C22H25NO2Couleur et forme :SolidMasse moléculaire :335.44Pipequaline hydrochloride
CAS :Pipequaline hydrochloride (PK-8165 hydrochloride) is an anticonflict & anticonvulsant quinoline derivative.Formule :C22H25ClN2Degré de pureté :99.46%Couleur et forme :SolidMasse moléculaire :352.9Gabazine
CAS :Gabazine (SR95531) is an antagonist of GABAA receptors (Ki : 74-150 nM)Formule :C15H18BrN3O3Degré de pureté :98.51% - 99.24%Couleur et forme :SolidMasse moléculaire :368.23Temgicoluril
CAS :Temgicoluril (mebikar) acts on GABA Receptor.Formule :C8H14N4O2Degré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :198.22Gaboxadol hydrochloride
CAS :Gaboxadol (hydrochloride) is a GABAA receptor agonist.Formule :C6H9ClN2O2Degré de pureté :99.39%Masse moléculaire :176.601Phenibut (hydrochloride)
CAS :Phenibut hydrochloride (3-Amino-4-phenylbutyric acid hydrochloride) is a GABA mimetic that acts as an agonist at GABAB receptors.Formule :C10H14ClNO2Degré de pureté :99.93%Couleur et forme :White Crystalline PowderMasse moléculaire :215.68Piperazine citrate
CAS :Piperazine citrate, an organic compound, consists of a six-membered ring, containing two nitrogen atoms at opposite positions in the ring.Formule :C24H46N6O14Degré de pureté :99.8%Couleur et forme :Crystals IndicationMasse moléculaire :642.652'-O-Methylisoliquiritigenin
CAS :2'-O-Methylisoliquiritigenin, a compound synthesized by enzymes specifically induced in NR.2'-O-Methylisoliquiritigenin, isolated from the Arachis species, up-Formule :C16H14O4Degré de pureté :98.75%Couleur et forme :SolidMasse moléculaire :270.28Fluralaner
CAS :Fluralaner (A1443) is an isoxazoline ectoparasiticide.Formule :C22H17Cl2F6N3O3Degré de pureté :99.72% - 99.99%Couleur et forme :Solid PowderMasse moléculaire :556.29SKF89976A hydrochloride
CAS :SKF89976A hydrochloride (d,l-SKF89976A hydrochloride) is a selective inhibitor GABA transporter such as GAT-1 (IC50s = 0.28 μM), GAT-2 (IC50s = 137.34 μM) andFormule :C22H26ClNO2Degré de pureté :98.02%Couleur et forme :SolidMasse moléculaire :371.9Ref: TM-T12930
1mg34,00€5mg65,00€10mg89,00€25mg167,00€50mg264,00€100mg409,00€200mg590,00€1mL*10mM (DMSO)71,00€(2S)-6-Prenylnaringenin
CAS :(2S)-6-Prenylnaringenin (6-Prenylnaringenin) is an isomer of the potent phytoestrogen, 8-prenylnaringenin.Formule :C20H20O5Degré de pureté :99.47%Couleur et forme :SolidMasse moléculaire :340.37α-Thujone
CAS :α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.Formule :C10H16ODegré de pureté :97.02% - 98.41%Couleur et forme :Less Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996) Colorless Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996)Masse moléculaire :152.23Tiagabine
CAS :Tiagabine (NO050328) is an Anti-epileptic Agent.Formule :C20H25NO2S2Degré de pureté :99.25% - 99.67%Couleur et forme :White To Off-White Crystalline SolidMasse moléculaire :375.55Fipronil
CAS :Fipronil (Fluocyanobenpyrazole) is a broad-use insecticide that belongs to the phenylpyrazole chemical family.Formule :C12H4Cl2F6N4OSDegré de pureté :97.21%Couleur et forme :Solid PowderMasse moléculaire :437.15Cholesterol myristate
CAS :Cholesterol myristate, a natural steroid in Chinese medicine, affects GABAA, nicotinic receptors, and potassium channels.
Formule :C41H72O2Degré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :597.01Acetoxyvalerensre
CAS :Acetoxyvalerensre (acetylvalerenolic acid) (acetylvalerenolic acid) is a derivative of valerenic acid, which is a a GABAA receptor modulator.
Formule :C17H24O4Degré de pureté :98.22%Couleur et forme :SolidMasse moléculaire :292.37α-Asarone
CAS :alpha-Asarone (trans-Asarone) is a psychoactive compound with antidepressant-like activity in mice.Formule :C12H16O3Degré de pureté :99.64% - 99.64%Couleur et forme :Monoclinic Needles From Water Monoclinic Needles From WaterMasse moléculaire :208.25Miltirone
CAS :Miltirone is a CYPs inhibitor, it has been characterized as a low-affinity ligand for central benzodiazepine receptors.Formule :C19H22O2Degré de pureté :99.22% - 99.66%Couleur et forme :SolidMasse moléculaire :282.38Amentoflavone
CAS :Amentoflavone (3',8''-Biapigenin), as a potent inhibitor of CYP3A4 and CYP2C9, can interact with many other medications.Formule :C30H18O10Degré de pureté :98.21% - 99.22%Couleur et forme :Odourless Whitish SolidMasse moléculaire :538.46Ref: TM-T3417
2mg34,00€5mg50,00€10mg80,00€25mg126,00€50mg215,00€100mg349,00€200mg512,00€1mL*10mM (DMSO)59,00€AZD-6280
CAS :AZD6280 is a novel, subtype-selective GABAAα2/3 receptor positive modulators, used for treatment of generalized anxiety disorder.Formule :C20H22N4O3Degré de pureté :98.99%Couleur et forme :SolidMasse moléculaire :366.41Ref: TM-T7136
1mg215,00€5mg439,00€10mg640,00€25mg1.018,00€50mg1.423,00€100mg1.935,00€1mL*10mM (DMSO)484,00€CL 218872
CAS :CL 218872: selective α1 GABAA receptor agonist, anxiolytic, and anticonvulsant; Ki=130 nM for α1, less potent for α2-α6.Formule :C13H9F3N4Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :278.23p-Hydroxybenzaldehyde
CAS :1.Formule :C7H6O2Degré de pureté :99.05% - 99.86%Couleur et forme :SolidMasse moléculaire :122.12Songorine
CAS :Songorine (Napellonine) shows anti-tumor activity in preliminary pharmacological verification trials including cell proliferation and molecular docking assays.Formule :C22H31NO3Degré de pureté :98% - 99.92%Couleur et forme :SolidMasse moléculaire :357.49Cyclothiazide
CAS :Cyclothiazide enhances AMPA receptors, prevents desensitization, and boosts glutamic acid response (EC50 = 3.8µM).Formule :C14H16ClN3O4S2Degré de pureté :98.23% - 99.49%Couleur et forme :Crystals From Dilute Alcohol SolidMasse moléculaire :389.88
