Facteur Xa
Le facteur Xa est une enzyme cruciale dans la cascade de coagulation qui convertit la prothrombine en thrombine, entraînant la formation de caillots sanguins. L'inhibition du facteur Xa est une stratégie thérapeutique largement utilisée pour prévenir et traiter les troubles thromboemboliques, tels que la thrombose veineuse profonde, l'embolie pulmonaire et l'AVC. Chez CymitQuimica, nous proposons des inhibiteurs du facteur Xa pour soutenir vos recherches en hématologie, santé cardiovasculaire et thérapie anticoagulante.
80 produits trouvés pour "Facteur Xa"
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Ciraparantag TFA
CAS :<p>Ciraparantag TFA reverses anticoagulants by inhibiting thrombin and factor Xa.</p>Formule :C26H50F6N12O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :740.74Ciraparantag
CAS :<p>Ciraparantag inhibits thrombin, factor Xa, and reverses various anticoagulants.</p>Formule :C22H48N12O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :512.7Darexaban glucuronide
CAS :<p>Darexaban glucuronide is the major component in plasma after oral administration of darexaban to humans. Darexaban (YM150) is a direct inhibitor of factor Xa.</p>Formule :C33H38N4O10Couleur et forme :SolidMasse moléculaire :650.68Tanogitran
CAS :<p>Tanogitran, a coagulation factor Xa inhibitor, is used potentially for the treatment of septic shock.</p>Formule :C25H31N7O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :477.56DPC-423
CAS :<p>DPC-423 is a factor Xa inhibitor potentially for the treatment of thrombosis.</p>Formule :C25H21ClF4N4O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :568.97Razaxaban hydrochloride
CAS :<p>Razaxaban hydrochloride is a highly potent, selective and orally active inhibitor of factor Xa(Ki of 0.19 nM),has strongly antithrombotic activity.</p>Formule :C24H21ClF4N8O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :564.92Otamixaban
CAS :<p>Otamixaban (FXV673) is a selective and highly effective Xa inhibitor that inhibits the generation of thrombin and can be used to study acute coronary syndrome.</p>Formule :C25H26N4O4Degré de pureté :98.08%Couleur et forme :SolidMasse moléculaire :446.5Eribaxaban
CAS :<p>Eribaxaban (PD348292) is an orally available factor Xa inhibitor for the prevention and treatment of venous thromboembolism.</p>Formule :C24H22ClFN4O4Degré de pureté :98.99% - 99.13%Couleur et forme :SolidMasse moléculaire :484.91Fidexaban
CAS :<p>Fidexaban (CI1031) is a novel, potent, selective and orally active factor Xa inhibitor that has demonstrated antithrombotic activity in a variety of assays</p>Formule :C25H24F2N6O5Degré de pureté :98.64% - 99.43%Couleur et forme :SolidMasse moléculaire :526.49LY 517717
CAS :<p>LY 517717 is an orally active inhibitor of coagulation factor Xa with antithrombotic activity for the study of venous thromboembolism (VTE).</p>Formule :C27H33N5O2Degré de pureté :99.77% - 99.88%Couleur et forme :SolidMasse moléculaire :459.58Edoxaban
CAS :<p>Edoxaban: potent, selective FXa inhibitor; Ki 0.561 nM. Used as an oral anticoagulant for stroke prevention, also inhibits thrombin and FIXa.</p>Formule :C24H30ClN7O4SDegré de pureté :97.67% - 99.71%Couleur et forme :SolidMasse moléculaire :548.06Zifaxaban
CAS :<p>Zifaxaban (TY-602) is an oral selective factor Xa inhibitor with an IC50 of 11.1 nM, highly specific over other serine proteases, used in thrombosis studies.</p>Formule :C20H16ClN3O4SDegré de pureté :97.46% - 99.82%Couleur et forme :SolidMasse moléculaire :429.88BMS-262084
CAS :<p>BMS-262084 is a potent selective β-lactam trypsin inhibitor with therapeutic potential in the treatment of asthma.</p>Formule :C18H31N7O5Couleur et forme :SolidMasse moléculaire :425.48FXIa-IN-1
CAS :<p>FXIa-IN-1 is a potent β-lactam covalent heparin-derived factor XIa (fXIa) inhibitor.</p>Formule :C20H19F3N4O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :452.38Frunexian
CAS :<p>Frunexian (EP-7041) is a selective and potent inhibitor of coagulation factor XI/activated factor XI, specifically targeting XIa.</p>Formule :C19H26N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :374.43AS1468240
CAS :<p>AS1468240 is a factor Xa inhibitor. It has significant oral anticoagulant activity.</p>Formule :C25H25Cl2N5O3Couleur et forme :SolidMasse moléculaire :514.4BI-11634
CAS :<p>BI-11634 is a factor Xa inhibitor.</p>Formule :C22H23ClN4NaO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :465.89BMS-962212
CAS :<p>BMS-962212: reversible, selective FXIa blocker, well-tolerated, quick PD effect, rapid clearance, alters clotting time/activity.</p>Formule :C32H28ClFN8O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :659.07FXIa-IN-7
CAS :<p>FXIa-IN-7 is an orally available, selective and potent inhibitor of factor XIa for the study of thrombophilia.</p>Formule :C28H28N2O4Degré de pureté :98.55%Couleur et forme :SolidMasse moléculaire :456.53BMS-654457
CAS :<p>BMS-654457 is a small-molecule, reversible inhibitor of factor XIa (FXIa; Kis: 0.2 and 0.42 nM for human and rabbit FXIa).</p>Formule :C36H37N5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :603.71FXa-IN-1
CAS :<p>FXa-IN-1, an FXa blocker: IC50=3 nM, Ki=0.7 nM, orally available, long half-life, for thrombosis research.</p>Formule :C24H18F5N5OCouleur et forme :SolidMasse moléculaire :487.42Dechloro Rivaroxaban
CAS :<p>Dechloro Rivaroxaban is a Factor Xa inhibitor that inhibits free FXa and plasminogen and fibrin-associated FXa activity in humans.</p>Formule :C19H19N3O5SDegré de pureté :98.63%Couleur et forme :SolidMasse moléculaire :401.44DX-9065A HCl hydrate
CAS :<p>DX-9065a: Competitive fXa/prothrombinase inhibitor; blocks proinflammatory events; Ki ~10-20 nM.</p>Formule :C26H39ClN4O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :571.06BAY 3389934
CAS :<p>BAY 3389934 is a dual inhibitor of factor IIa (factor IIa) and factor Xa (factor Xa), providing anticoagulant and organ-protective effects. It alleviates coagulopathy and organ dysfunction in baboon models of Staphylococcus aureus sepsis.</p>Formule :C26H30ClN5O7S2Couleur et forme :SolidMasse moléculaire :624.129RWJ-445167
CAS :<p>RWJ-445167 is a thrombin and factor Xa dual inhibitor(Ki of 4.0 nM and 230 nM, respectively), with potent antithrombotic activity.</p>Formule :C18H24N6O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :436.49FXIa-6f
CAS :<p>FXIa-6f is a high affinity, orally bioavailable macrocyclic FXIa inhibitor with antithrombotic activity in preclinical species</p>Formule :C31H29ClF2N4O4Couleur et forme :SolidMasse moléculaire :595.04FXIa-IN-6
CAS :<p>FXIa-IN-6: Potent, selective FXIa inhibitor (Ki=0.3 nM); strong PK with high oral bioavailability, low clearance preclinically.</p>Formule :C31H29ClF2N4O4Couleur et forme :SolidMasse moléculaire :595.04FXIa-IN-9
CAS :<p>FXIa-IN-9, a potent FXIa inhibitor (K i : human 0.17 nM, rabbit 0.5 nM), forms hydrogen bonds and has anticoagulant properties.</p>Formule :C23H18Cl2F3N9O2Couleur et forme :SolidMasse moléculaire :580.35FXIa-IN-8
<p>FXIa-IN-8: potent FXIa blocker (IC50: 14.2 nM), anti-thrombotic, low bleeding/toxicity risk.</p>Couleur et forme :Solid5-Chlorothiophene-2-carboxylic acid
CAS :<p>5-Chlorothiophene-2-carboxylic acid [catalog number: T66447, CAS number: 24065-33-6] is a valuable organic compound for life sciences research.</p>Formule :C5H3ClO2SCouleur et forme :SolidMasse moléculaire :162.59
