IDO
L'indoleamine 2,3-dioxygénase (IDO) est une enzyme impliquée dans le catabolisme du tryptophane, conduisant à la production de kynurénine et d'autres métabolites. L'IDO joue un rôle dans la tolérance immunitaire et est souvent surexprimée dans le cancer et les maladies inflammatoires chroniques. Les inhibiteurs de l'IDO sont explorés comme agents immunothérapeutiques potentiels dans le cancer et les maladies auto-immunes. Chez CymitQuimica, nous fournissons des inhibiteurs de l'IDO pour soutenir vos recherches en immunologie, oncologie et régulation métabolique.
88 produits trouvés pour "IDO".
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
IDO1/TDO-IN-11
IDO1/TDO-IN-11 (Compound Y-13) serves as a dual inhibitor of IDO1 and TDO, exhibiting an IC50 of 2.87 μM for hIDO1 and 0.08 μM for hTDO. It effectively reduces the production of NO and ROS. Additionally, IDO1/TDO-IN-11 mitigates cellular neuroinflammation damage and enhances conditions related to Parkinson's disease. This compound is applicable in Parkinson's disease research.NU223612
CAS :"NU223612 is a potent IDO1-degrading PROTAC with Kd 640 nM, binds CRBN at 290 nM, and crosses the BBB."Formule :C49H55FN6O9Couleur et forme :SolidMasse moléculaire :890.99PROTAC IDO1 Degrader-1
CAS :First potent PROTAC IDO1 degrader; links IDO1 to CRBN E3 ligase for UPS-induced degradation (DC50=2.84 μM), boosts H ER2 CAR-T cell efficacy.Formule :C40H53BrFN9O13Couleur et forme :SolidMasse moléculaire :966.816Anti-IDO1 Antibody (9Y885)
Anti-IDO1 Antibody (9Y885) is an antibody targeting IDO1. Anti-IDO1 Antibody (9Y885) can be used in ELISA, IHC.Couleur et forme :Odour LiquidIDO1 Protein, Human, Recombinant (His)
IDO Protein, Human, Recombinant (His) is expressed in E.Couleur et forme :Lyophilized PowderMasse moléculaire :46 kDa (predicted); 44 kDa (reducing conditions)(S)-IDO1-IN-5
CAS :(S)-IDO1-IN-5 is an active S-isomer of IDO1-IN-5. (S)-IDO1-IN-5 binds to IDOL(IC50 value less than 1.5 μΜ).Formule :C23H25FN2O3Couleur et forme :SolidMasse moléculaire :396.45IDO1 Protein, Mouse, Recombinant (His)
IDO Protein, Mouse, Recombinant (His) is expressed in E.Degré de pureté :≥ 90 % as determined by SDS-PAGE. - ≥ 90 % as determined by SDS-PAGE.Couleur et forme :White Lyophilized PowderMasse moléculaire :46.47 kDa (predicted)(Rac)-IDO1-IN-5
CAS :(Rac)-IDO1-IN-5 is a racemic, potent IDO1 inhibitor; selective for apo-IDO1, it crosses the blood-brain barrier.Formule :C23H25FN2O3Couleur et forme :SolidMasse moléculaire :396.45IDO1/TDO-IN-4
CAS :IDO1/TDO-IN-4 is a novel dual inhibitor of IDO1/TDO with antidepressant activity, forming hydrogen bonds with IDO1 and π-π stacking interactions with TDO.Formule :C14H10N4Degré de pureté :98.12% - 98.88%Couleur et forme :White SolidMasse moléculaire :234.26IDO1 Protein, Human, Recombinant
IDO Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 45.2 kDa and the accession number is A0A348GSI3.Couleur et forme :Transparent SolutionMasse moléculaire :45.2 kDa (predicted); 46 kDa (reducing conditions)(S)-Indoximod
CAS :(S)-Indoximod (L-Abrine) is an indoleamine-2,3-dioxygenase (IDO) inhibitor for cancer research.Formule :C12H14N2O2Degré de pureté :95.39% - 99.69%Couleur et forme :White SolidMasse moléculaire :218.25IDO-IN-7
CAS :IDO-IN-7 (NLG-919 analogue) is a potent IDO (indoleamine-(2, 3)-dioxygenase) pathway inhibitor.Formule :C18H22N2ODegré de pureté :99.32% - 99.9%Couleur et forme :SolidMasse moléculaire :282.38PCC0208009
CAS :PCC0208009 (IDO-IN-2) is an IDO inhibitor.Formule :C29H35N7ODegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :497.63Ref: TM-T4142
1mg44,00€2mg56,00€1mL*10mM (DMSO)92,00€5mg93,00€10mg142,00€25mg258,00€50mg439,00€100mg605,00€LM10
CAS :TDO inhibitor; IC50: human 0.62 μM, mouse 2 μM; selective over IDO, MAOs; hinders TDO+ tumor growth in mice; orally active.Formule :C11H8FN5Degré de pureté :98.78% - 99.94%Couleur et forme :SolidMasse moléculaire :229.21IDO5L
CAS :IDO5L (INCB024360 analogue) is an effective IDO1 inhibitor(IC50=10 nM).Formule :C9H7ClFN5O2Degré de pureté :99.49% - 99.67%Couleur et forme :SolidMasse moléculaire :271.64Ref: TM-T2647
1mL*10mM (DMSO)34,00€10mg48,00€25mg81,00€50mg117,00€100mg177,00€200mg304,00€500mg477,00€IDO1-IN-1
CAS :IDO1-IN-1 (2 HzBTZ) is an indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor.Formule :C7H7N3SDegré de pureté :99.36%Couleur et forme :Slightly Yellow To Beige-Green Crystalline PowderMasse moléculaire :165.216BMS-986242
CAS :BMS-986242 is an orally active, potent and selective inhibitor of indoleamine-2,3-dioxygenase 1 (IDO1), and it can be used for the research of cancer.Formule :C24H24ClFN2ODegré de pureté :98.9%Couleur et forme :White SolidMasse moléculaire :410.91Indoximod
CAS :Indoximod (NLG-8189) is a methylated tryptophan that inhibits IDO to boost T cell function by preventing tryptophan depletion.Formule :C12H14N2O2Degré de pureté :97.82% - 99.55%Couleur et forme :SolidMasse moléculaire :218.25Linrodostat mesylate
CAS :Linrodostat (BMS-986205) is an oral IDO1 inhibitor that boosts immune response and has anti-cancer properties.Formule :C25H28ClFN2O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :507.02Navoximod
CAS :Navoximod (GDC-0919) (NLG- 919, GDC-0919) is a potent indoleamine-(2,3)-dioxygenase (IDO) pathway inhibitor (Ki/EC50: 7 nM/75 nM).Formule :C18H21FN2O2Degré de pureté :99.37%Couleur et forme :White SolidMasse moléculaire :316.37Ref: TM-TQ0071
1mg150,00€5mg313,00€1mL*10mM (DMSO)318,00€10mg470,00€25mg600,00€50mg745,00€100mg1.044,00€
