Anhydrase carbonique
L'anhydrase carbonique est une enzyme qui catalyse la conversion réversible du dioxyde de carbone et de l'eau en bicarbonate et protons. Cette enzyme joue un rôle crucial dans le maintien de l'équilibre acido-basique, la respiration et le transport du dioxyde de carbone dans le sang. Les inhibiteurs de l'anhydrase carbonique sont utilisés dans le traitement du glaucome, de l'épilepsie et du mal des montagnes, ainsi que dans la recherche sur l'homéostasie acido-basique et les échanges gazeux. Chez CymitQuimica, nous offrons une gamme d'inhibiteurs de l'anhydrase carbonique et de réactifs de haute qualité pour soutenir vos recherches en enzymologie, physiologie respiratoire et développement thérapeutique.
177 produits trouvés pour "Anhydrase carbonique"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
hCAXII-IN-5
CAS :<p>hCAXII-IN-5, or compound 6o, is a potent, selective hCAXII inhibitor with Ki values: hCAI & II >10000, hCAIX 286.1, hCAXII 1.0 nM.</p>Formule :C23H22N2O4Couleur et forme :SolidMasse moléculaire :390.43AHR-15010
CAS :<p>AHR-15010 is a novel anti-arthritic agent.</p>Formule :C10H16N2O8S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :356.37L-693612 HCl
CAS :<p>L-693612 HCl is an inhibitor of carbonic anhydrase.</p>Formule :C14H25ClN2O5S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :433.01hCAIX-IN-7
CAS :<p>hCAIX-IN-7 (6c) selectively inhibits tumor-related isoform hCAIX (KI: 410.6 nM) and weakly affects hCAI/II (KI: >10000 nM).</p>Formule :C18H12FNO3Couleur et forme :SolidMasse moléculaire :309.29Carbonic anhydrase inhibitor 13
CAS :<p>Carbonic anhydrase inhibitor 13 (compound 7) is a potent inhibitor of carbonic anhydrase (CA).</p>Formule :C17H15N5O3S2Couleur et forme :SolidMasse moléculaire :401.46hCAIX-IN-3
CAS :<p>hCAII-IN-3 (7e) selectively inhibits CA II/IX with Kis of 124.2/30.5 nM, showing promise for cancer treatment.</p>Formule :C21H21BrN6O4SCouleur et forme :SolidMasse moléculaire :533.4hCAIX-IN-14
CAS :<p>hCAIX-IN-14 is a potent inhibitor of human CA IX with a K i value of 134.8 nM .</p>Formule :C11H17ClN6O2SCouleur et forme :SolidMasse moléculaire :332.81Carbonic anhydrase inhibitor 7
CAS :<p>Potent hCA inhibitor; targets hCA IX, II, XII, I with Ki: 6.5, 7.1, 72.1, 255.8 nM respectively.</p>Formule :C23H17N3O5SCouleur et forme :SolidMasse moléculaire :447.46hCAXII-IN-1
CAS :<p>hCAXII-IN-1 selectively inhibits HCA IX/XII, promising for new cancer drug development.</p>Formule :C20H17NO5Couleur et forme :SolidMasse moléculaire :351.35Quinethazone
CAS :<p>Quinethazone is a thiazide diuretic used to treat hypertension. Common side effects include dizziness, dry mouth, nausea, and low potassium levels.</p>Formule :C10H12ClN3O3SCouleur et forme :Fibrous Crystals From 50% Acetone Physical Description Fibrous Crystals Or White Powder (Ntp 1992)Masse moléculaire :289.74hCAIX-IN-10
CAS :<p>"hCAIX-IN-10 (6i) selectively inhibits carbonic anhydrase IX/XII (Ki: 61.5/586.8 nM), markers in tumor cells, affecting acid-base balance."</p>Formule :C28H21N3O3SCouleur et forme :SolidMasse moléculaire :479.55hCAIX-IN-6
CAS :<p>6B and 14g inhibit tumor-associated HCA IX with low nanomolar potency; 6K targets HCA XII. All are potential cancer drug leads.</p>Formule :C18H12N2O4SCouleur et forme :SolidMasse moléculaire :352.36DTP348
CAS :<p>DTP348: Oral carbonic anhydrase IX inhibitor & hypoxic cell radiosensitizer with sulfamide & 5-nitroimidazole components.</p>Formule :C6H11N5O4SCouleur et forme :SolidMasse moléculaire :249.25Carbonic anhydrase inhibitor 11
CAS :<p>Potent carbonic anhydrase inhibitor VI targets CA II, IX, XII with Ki: 40, 39, 900 nM respectively.</p>Formule :C19H15F3N4O3S2Couleur et forme :SolidMasse moléculaire :468.47hCAIX/XII-IN-4
CAS :<p>hCAIX/XII-IN-4 inhibits CAIX/XII with Ki: 4.5 nM (CAXII), 23.6 nM (CAIX), and >10000 nM (CAI/CAII).</p>Formule :C20H16N2O5Couleur et forme :SolidMasse moléculaire :364.35hCAXII-IN-4
CAS :<p>hCAXII-IN-4 is a selective and potent CA XII inhibitor with a Ki value of 6.4 nM for human CA XII.</p>Formule :C22H27N5O6SCouleur et forme :SolidMasse moléculaire :489.54hCAI/II-IN-2
CAS :<p>hCAI/II-IN-2 (2b) inhibits hCA I/II (Ki: 40.97 nM, 15.15 nM) and IX (61.88 nM), fights AMS with anti-hypoxic effects, but has low cellular activity.</p>Formule :C12H12N4O5S2Couleur et forme :SolidMasse moléculaire :356.38hCA IX-IN-2
<p>hCA IX-IN-2 is a highly potent and selective inhibitor of hCA IX, exhibiting an inhibition constant (K I) value of 32.1 nM and demonstrating anti-proliferative</p>Formule :C23H24N2O4STeCouleur et forme :SolidMasse moléculaire :552.11hCAI/II-IN-3
CAS :<p>"hCAI/II-IN-3 (compound 5b) is a potent dual hCA I/II inhibitor with Ki: 51.25nM (I), 13.15nM (II), helps treat AMS."</p>Formule :C16H18N4O4S2Couleur et forme :SolidMasse moléculaire :394.47hCAIX/XII-IN-6
<p>hCAIX/XII-IN-6: Oral carbonic anhydrase inhibitor, targets hCA I/II/IV/IX/XII, aids rheumatoid arthritis research. Ki: 6697/2950/4093/4.1/7.7 nM.</p>Formule :C26H23N3O6S4Couleur et forme :SolidMasse moléculaire :601.74hCAII-IN-1
CAS :<p>hCAII-IN-1 (7f) inhibits CA II/IX with Kis 1.2 nM/113.6 nM, potential for cancer treatment.</p>Formule :C21H21BrN6O4SCouleur et forme :SolidMasse moléculaire :533.4hCAIX-IN-8
CAS :<p>hCAIX-IN-8, a selective hCAIX inhibitor, IC50: 0.024 μM. Also affects CAII, CAVA (IC50s: 1.99, 1.10 μM), limits cell migration, and induces apoptosis.</p>Formule :C19H16N4O6Couleur et forme :SolidMasse moléculaire :396.35hCAXII-IN-2
CAS :<p>hCAXII-IN-2 is a potent inhibitor of hCA XII (Ki: 84.2 nM) and hCA IX (Ki: 268.5 nM), with low activity on hCA I/II.</p>Formule :C21H18ClN3O4Couleur et forme :SolidMasse moléculaire :411.84hCA I-IN-2
CAS :<p>hCA I-IN-2 (6d) inhibits hCA I (Ki: 18.8 nM) more selectively over II, IX, XII (Ki: 375.1, 1721, 283.9 nM).</p>Formule :C26H20BrN5O3SCouleur et forme :SolidMasse moléculaire :562.44FC11409B
CAS :<p>FC11409B is a CAIX inhibitor, inhibiting breast cancer invasion and metastasis.</p>Formule :C29H23BF4N2O3SCouleur et forme :SolidMasse moléculaire :566.38hCAI/II-IN-4
CAS :<p>hCAI/II-IN-4 inhibits hCA I & II (Ki: 16.95 & 15.22 nM), hCA IX (Ki: 27.04 nM), has anti-hypoxia benefits and is low-toxic for AMS research.</p>Formule :C15H15N3O5S2Couleur et forme :SolidMasse moléculaire :381.43Methazolamide-d6
CAS :<p>Methazolamide-d6 is a GC/LC-MS standard for measuring methazolamide, a glaucoma drug that lowers eye pressure and fluid, reduces seizures, and combats ROS.</p>Formule :C5H2D6N4O3S2Couleur et forme :SolidMasse moléculaire :242.31L 662583
CAS :<p>L 662583 is a topical inhibitor of carbonic anhydrase.</p>Formule :C13H17ClN2O5S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :412.93L-693612
CAS :<p>L-693612 is an inhibitor of carbonic anhydrase.</p>Formule :C14H24N2O5S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :396.55L 645151
CAS :<p>L 645151 is an inhibitor of lipophilic CA.</p>Formule :C12H14N2O4S2Couleur et forme :SolidMasse moléculaire :314.38hCAIX-IN-5
CAS :<p>hCAIX-IN-5 was a selective hCAIX inhibitor, inhibiting hCAI, hCAII, hCAIV, and hCAIX with Ki values of >10000, >10000, 130.7, and 829.1 nM, respectively.</p>Formule :C18H12FNO3Degré de pureté :99.26%Couleur et forme :SolidMasse moléculaire :309.29WES-1
CAS :<p>WES-1 (Compound 8g), a carbonic anhydrase IX inhibitor (Ki: 55.9 μM), exhibits broad-spectrum antiproliferative activity against various cancer cell lines,</p>Formule :C20H20N4O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :396.46hCAI/II-IN-6
CAS :<p>hCAI/II-IN-6 is a selective and orally active inhibitor of human carbonic anhydrase (CA).</p>Formule :C19H24N4O3SDegré de pureté :97.07%Couleur et forme :SolidMasse moléculaire :388.48hCAII-IN-9
CAS :<p>hCAII-IN-9 inhibits hCA II/IX/XII with IC50s of 1.18, 0.17, 2.99 μM; not BBB permeable.</p>Formule :C15H16ClN3O5S2Degré de pureté :98.63%Couleur et forme :SolidMasse moléculaire :417.89Sultiame
CAS :<p>Sultiame is an inhibitor of carbonic anhydrase. Sultiame can be used in antiepileptic research.</p>Formule :C10H14N2O4S2Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :290.36Carbonic anhydrase inhibitor 6
CAS :<p>Carbonic anhydrase inhibitor 6 is an hCA inhibitor that inhibits hCA IX, hCA II, hCA XII, and hCA I. It is used in the study of lupus erythematosus.</p>Formule :C26H25N3O5SDegré de pureté :98.81%Couleur et forme :SolidMasse moléculaire :491.56hCAIX/XII-IN-8
CAS :<p>hCAIX/XII-IN-8 (compound 3g) is a potent inhibitor of the human carbonic anhydrases (CAs) IX and XII, with inhibition constants (K i) of 8.5 nM for CA IX and 6.</p>Formule :C16H13Cl2N5O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :426.28Carbonic anhydrase inhibitor 12
CAS :<p>CA Inhibitor 12 strongly blocks CA II (K_i 1.72 nM), also inhibits CA I (271 nM), shows anticancer effects.</p>Formule :C27H22BrN5O5S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :640.53N-Desethyl Brinzolamide oxalate
CAS :<p>N-Desethyl Brinzolamide oxalate functions as a dual inhibitor targeting Carbonic anhydrase II and Carbonic anhydrase IV, exhibiting inhibitory concentrations (IC50) of 1.28 nM and 128 nM, respectively [1].</p>Formule :C12H19N3O9S3Couleur et forme :SolidMasse moléculaire :445.49COX-2-IN-30
CAS :<p>COX-2-IN-30, a benzenesulfonamide derivative, is an orally active, dual inhibitor of cyclooxygenase-2 (COX-2; IC50 = 49 nM) and cyclooxygenase-1 (COX-1; IC50 =</p>Formule :C17H16N6O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :384.41hCAIX-IN-16
CAS :<p>hCAIX-IN-16 (Compound 12d), an inhibitor of hCA IX, exhibits inhibition constants (K i) of 190.0 nM for hCA IX and 187.9 nM for hCA XII.</p>Formule :C20H20N8O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :436.49ALP/Carbonic anhydrase-IN-1
CAS :<p>Compound 1e, also known as ALP/Carbonic anhydrase-IN-1, is a dual inhibitor targeting both carbonic anhydrase (CA) isozymes II, IX, and XII, as well as alkaline</p>Formule :C15H16N2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :224.3CAXII-IN-1
CAS :<p>CAXII-IN-1, antitumor, selectively inhibits CA XII with Ki of 3.8 nM for hCA XII and 56 nM for hCA IX.</p>Formule :C13H7Cl2NO3SCouleur et forme :SolidMasse moléculaire :328.17hCAIX-IN-15
CAS :<p>hCAIX-IN-15 is a potent inhibitor of human carbonic anhydrase IX (hCA IX) with an inhibition constant (Ki) of 38.8 nM, exhibiting broad-spectrum anticancer</p>Formule :C18H14FN7O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :411.41CAII-IN-2
<p>CAII-IN-2 (3g): potent, selective CA-II inhibitor; IC50-12.1 μM for bovine CA-II; valuable in CA-related disorder research.</p>Formule :C18H19BrN4SCouleur et forme :SolidMasse moléculaire :403.34Carbonic anhydrase inhibitor 5
<p>Potent hCA inhibitor: targets hCA II, IX & XII with IC50s of 42.9, 47.6, & 6.7 nM respectively.</p>Formule :C24H20ClN3O3SCouleur et forme :SolidMasse moléculaire :465.95Carbonic anhydrase inhibitor 9
<p>Carbonic anhydrase inhibitor 9 targets hCA II and IX with Ki of 56.4 and 56.9 nM respectively; shows antiproliferative activity.</p>Formule :C22H20BrN5O4SCouleur et forme :SolidMasse moléculaire :530.39hCAII-IN-5
CAS :<p>hCAII-IN-5 (compound 12h) is a potent, selective inhibitor of human carbonic anhydrase II (hCA II) with an inhibition constant (IC50) of 4.55 µM [1].</p>Formule :C29H18N2O7Couleur et forme :SolidMasse moléculaire :506.46hCAII-IN-3
<p>hCAII-IN-3 inhibits key hCA isoforms with Ki: hCA I (403.8 nM), hCA II (5.1 nM), hCA IX (10.2 nM), hCA XII (5.2 nM); shows anticancer potential.</p>Formule :C17H21N3O3SCouleur et forme :SolidMasse moléculaire :347.43Valerate sodium
CAS :<p>Valerate sodium is a potential Carbonic anhydrase 1/2 inhibitor for biochemical experiments.</p>Formule :C5H9NaO2Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :124.11O-Desmethyl Brinzolamide hydrochloride
CAS :<p>O-Desmethyl Brinzolamide hydrochloride (compound 6a), a potent metabolite derived from Brinzolamide, serves as a carbonic anhydrase (CA) inhibitor. It exhibits a dissociation constant (Kd) of 0.136 nM for CA II and an inhibitory concentration (IC50) of 165 nM for CA IV [1].</p>Formule :C11H20ClN3O5S3Couleur et forme :SolidMasse moléculaire :405.94hCAIX/XII-IN-15
CAS :<p>hCAIX/XII-IN-15 (Compound 17β) is an inhibitor of hCA IX and hCA XII, exhibiting Ki values of 0.42 and 4.37 μM, respectively. It demonstrates a pro-apoptotic effect in multiple myeloma cells.</p>Formule :C17H18O4SCouleur et forme :SolidMasse moléculaire :318.387Carbonic anhydrase inhibitor 4
<p>CA inhibitor 4, photoprobe; targets hCA I-XIV; Ki: 640-1166 nM.</p>Formule :C21H18N2O4SCouleur et forme :SolidMasse moléculaire :394.44Perfluorohexane sulfonamide
CAS :<p>Perfluorohexane sulfonamide (FHxSA) serves as an inhibitor of carbonic anhydrase (CA), effectively inhibiting bovine CA and human CAII with IC50 values of 0.122 and 1.38 μM, respectively. Additionally, it acts as a delayed-action insecticide for controlling red imported fire ants (Solenopsis invicta). Furthermore, Perfluorohexane sulfonamide is considered a potential environmental pollutant.</p>Formule :C6H2F13NO2SCouleur et forme :SolidMasse moléculaire :399.13AChE/CA I-IN-1
<p>AChE/CA I-IN-1 (Compound 2g) acts as an inhibitor for both AChE and hCA I, with Ki values of 1.85 µM and 0.53 µM, respectively. It has shown potential applications in the research of Alzheimer's disease, glaucoma, and epilepsy.</p>Formule :C14H19NO6SCouleur et forme :SolidMasse moléculaire :329.374-Acetylphenylboronic acid
CAS :<p>4-Acetylphenylboronic acid acts as an effective inhibitor targeting carbonic anhydrase II (CAII), displaying inhibitory concentrations (IC50) of 246 μM for bovine CAII (bCA II) and 281.40 μM for human CAII (hCA II).</p>Formule :C8H9BO3Couleur et forme :SolidMasse moléculaire :163.97CA IX-IN-1
<p>CA IX-IN-1 (compound 12g) is a potent and highly selective hCA IX inhibitor (IC50: 7 nM) that exhibits antitumour effects.</p>Formule :C16H22N4O8SCouleur et forme :SolidMasse moléculaire :430.43hCAI/II/XII-IN-1
CAS :<p>hCAI/II/XII-IN-1 (compound 7) is an inhibitor of human carbonic anhydrases hCAI, hCAII, and hCAXII, with Ki values of 78.5 nM, 9.1 nM, 605 nM, 7.7 nM, and 3.7 nM.</p>Formule :C12H12N2O2SCouleur et forme :SolidMasse moléculaire :248.301CA IX-IN-3
CAS :<p>CAIX-IN-3 (Compound 27) is a selective and potent inhibitor of carbonic anhydrase IX (CAIX), with an IC50 of 0.48 nM.</p>Formule :C21H19N5O4S2Couleur et forme :SolidMasse moléculaire :469.537Carbonic anhydrase inhibitor 17
CAS :<p>Carbonic anhydrase inhibitor 17 (compound 7c) is a pyrazine-based sulfonamide that acts as a carbonic anhydrase II inhibitor, with an IC50 value of 0.63 nM.</p>Formule :C18H15ClN4O3S2Masse moléculaire :434.92Carbonic anhydrase inhibitor 16
CAS :<p>Carbonic anhydrase inhibitor 16 (compound 1) is a CA I/CA II inhibitor with potential antiviral activity, used in virus infection studies.</p>Formule :C14H10N2O4SDegré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :302.31CAII-IN-1
<p>CAII-IN-1 (3n) is a selective bovine CA-II inhibitor with 10.3 μM IC50, used in carbonic anhydrase disorder studies.</p>Formule :C19H21FN4SCouleur et forme :SolidMasse moléculaire :356.46Sulclamide
CAS :<p>Sulclamide, a sulfamoylbenzoic acid derivative, exhibits diuretic activity and functions as an inhibitor of carbonic anhydrase [1].</p>Formule :C7H7ClN2O3SCouleur et forme :SolidMasse moléculaire :234.66hCAVII/IX-IN-1
CAS :<p>hCAVII/IX-IN-1 (compound 4) functions as an inhibitor of hCAVII/IX, exhibiting Ki values of 56.5 nM and 38.2 nM, respectively. It is applicable in the field of cancer research.</p>Formule :C7H7N3O2S2Couleur et forme :SolidMasse moléculaire :229.279CAII-IN-3
<p>CAII-IN-3, a thiosemicarbazone, potently inhibits CA-II with an IC50 of 13.4 μM.</p>Formule :C18H18F2N4SCouleur et forme :SolidMasse moléculaire :360.42β-Glucuronidase/hCAII-IN-2
<p>β-Glucuronidase/hCAII-IN-2 is a potent inhibitor of β-glucuronidase and hCA II, and their IC50 values were 670.7 μM and 21.77 μM, respectively.</p>Formule :C31H23NO8Couleur et forme :SolidMasse moléculaire :537.52Carbonic anhydrase inhibitor 19
CAS :<p>Carbonic anhydrase inhibitor19 (compound 26a) targets glaucoma-associated isozymes hCA II and hCA XII, with inhibition constants (Kis) of 9.4 nM and 6.7 nM, respectively. This compound is effective in reducing intraocular pressure.</p>Formule :C23H25N3O6S2Masse moléculaire :503.59Carbonic anhydrase inhibitor 2
CAS :<p>Compound 7c inhibits carbonic anhydrase II, lowering intraocular pressure in glaucomatous rabbits.</p>Formule :C12H16N4O6SCouleur et forme :SolidMasse moléculaire :344.34α-Glucosidase-IN-63
CAS :<p>α-Glucosidase-IN-63 (Compound 4d) serves as an α-Glucosidase inhibitor with an IC 50 value of 0.44 μM. Additionally, it exhibits inhibitory activity against hCA II, demonstrating a K i of 7.0 nM. The compound is also effective when administered orally. [1]</p>Formule :C16H12FN3O3S2Couleur et forme :SolidMasse moléculaire :377.41hCAII-IN-4
CAS :<p>hCAII-IN-4 (Compound 12j) is a potent inhibitor of human carbonic anhydrase II (hCA II), exhibiting an inhibitory concentration (IC50) of 7.78 μM.</p>Formule :C31H23NO9Couleur et forme :SolidMasse moléculaire :553.52Carbonic anhydrase inhibitor 8
<p>R-13, a carbonic anhydrase inhibitor, has Ki of 60.7 nM (hCA I), 320.7 nM (hCA II), and 2298 nM (hCA IV).</p>Formule :C20H25N3O4SCouleur et forme :SolidMasse moléculaire :403.5Carbonic anhydrase inhibitor 3
<p>Carbonic anhydrase inhibitor 3 (compound 11g) is an inhibitor of carbonic anhydrase II that reduces the intraocular pressure in glaucomatous rabbits [1].</p>Formule :C15H17N3O3SCouleur et forme :SolidMasse moléculaire :319.38hCA XII/II/IX-IN-1
<p>hCA XII/II/IX-IN-1 inhibits hCA I/II/IX/XII (IC50: 2.6, 0.004, 0.005, 0.001 μM) with anticancer properties.</p>Formule :C25H34N4O7SCouleur et forme :SolidMasse moléculaire :534.63Carbonic anhydrase inhibitor 10
<p>CA inhibitor 10 targets MCF-7 cells, IC50: 11.9 μM; potent h CA IX inhibitor, Ki: 6.2 nM. Anti-cancer research.</p>Formule :C14H17N5O3SCouleur et forme :SolidMasse moléculaire :335.38β-Glucuronidase/hCAII-IN-1
CAS :<p>β-Glucuronidase/hCAII-IN-2 (Compound 12e) is a compound that effectively inhibits both β-glucuronidase and human Carbonic Anhydrase II (hCA II), exhibiting IC50</p>Formule :C30H21NO9Couleur et forme :SolidMasse moléculaire :539.49NSC 828467
<p>NSC 828467 is one of the top five CA-IX inhibitors with significant in vitro anticancer activity (IC50: 27.2 nM).</p>Formule :C21H19N9O2SCouleur et forme :SolidMasse moléculaire :461.5hCA VB-IN-1
<p>hCA VB-IN-1 (compound 15) is a potent and selective inhibitor of hCA VB (carbonic anhydrase) with a KI of 515.7 nM [1].</p>Formule :C9H13N3O4SCouleur et forme :SolidMasse moléculaire :259.28
