Anhydrase carbonique
L'anhydrase carbonique est une enzyme qui catalyse la conversion réversible du dioxyde de carbone et de l'eau en bicarbonate et protons. Cette enzyme joue un rôle crucial dans le maintien de l'équilibre acido-basique, la respiration et le transport du dioxyde de carbone dans le sang. Les inhibiteurs de l'anhydrase carbonique sont utilisés dans le traitement du glaucome, de l'épilepsie et du mal des montagnes, ainsi que dans la recherche sur l'homéostasie acido-basique et les échanges gazeux. Chez CymitQuimica, nous offrons une gamme d'inhibiteurs de l'anhydrase carbonique et de réactifs de haute qualité pour soutenir vos recherches en enzymologie, physiologie respiratoire et développement thérapeutique.
177 produits trouvés pour "Anhydrase carbonique"
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DPP IV/hCA II-IN-1
CAS :<p>DPP IV/hCA II-IN-1: strong DPP IV & CA inhibitor, IC50=0.049μM (DPP IV), Ki=0.0361-3.034μM (CA II-IV).</p>Formule :C17H20N2O5SCouleur et forme :SolidMasse moléculaire :364.42Bendroflumethiazide
CAS :<p>Bendroflumethiazide (Naturetin) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)</p>Formule :C15H14F3N3O4S2Degré de pureté :98% - >99.99%Couleur et forme :Crystals From Dioxane SolidMasse moléculaire :421.41Carbonic anhydrase
CAS :<p>Carbonic anhydrase, a zinc enzyme in all life forms, converts CO2 to bicarbonate; studied for cancer, glaucoma, obesity, epilepsy.</p>Couleur et forme :SolidCarbonic anhydrase inhibitor 26
<p>Compound 6T, designated as Carbonic anhydrase inhibitor26, acts as an inhibitor of Carbonic Anhydrase II (Carbonic AnhydraseII), exhibiting an IC50 value of 9.10 ± 0.26 μM.</p>Formule :C17H14N6O4Couleur et forme :SolidMasse moléculaire :366.33AV22-149
<p>AV22-149 (compound 22) is an inhibitor of Carbonic Anhydrase .</p>Formule :C23H28F3N3O6S2Couleur et forme :SolidMasse moléculaire :563.61DOTA-XYIMSR-01
CAS :<p>DOTA-XYIMSR-01 is a molecular probe targeting CAIX, capable of being labeled with 177Lu for the treatment and localization of malignant gliomas. The uptake of [177Lu]Lu-XYIMSR-01 in U87MG tumors is 6.19% injected dose per gram (% ID/g), with a tumor-to-muscle uptake ratio of 20.14. In an orthotopic glioma model, co-administration with temozolomide significantly enhances survival rates and inhibits tumor growth in mice. DOTA-XYIMSR-01 shows potential for research in the field of cancer treatment.</p>Formule :C61H88N16O22S2Couleur et forme :SolidMasse moléculaire :1461.57Acesulfame
CAS :<p>Acesulfame inhibits CA9/12 and can be used to study inflammation-related diseases.</p>Formule :C4H5NO4SCouleur et forme :SolidMasse moléculaire :163.15Carbonic anhydrase inhibitor 18
<p>Carbonic anhydrase inhibitor18 (Compound 9) is an inhibitor of human carbonic anhydrase (hCA) isozymes, with Ki values of 604.8 nM for hCA I, 333.6 nM for hCA II, 1.9 nM for hCA IX, and 6.7 nM for hCA XII. Carbonic anhydrase inhibitor18 is applicable in cancer research.</p>Formule :C26H28N4O6S2Masse moléculaire :556.14503Girentuximab
CAS :<p>Girentuximab (G250) is an anti-carbonic anhydrase IX (CAIX) monoclonal antibody with anti-cancer activity for the study of uroepithelial carcinoma PET (ZiPUP).</p>Couleur et forme :LiquidMasse moléculaire :145.55 kDahCAIX/XII-IN-11
<p>hCAIX/XII-IN-11 (Compound 6c) is an inhibitor of hCA IX and hCA XII, exhibiting Ki values of 0.7 μM for both isoforms. This compound is applicable in cancer research.</p>Formule :C13H10FN3O4Masse moléculaire :291.06553GZ22-4
<p>GZ22-4 is a near-infrared (NIR) fluorescent probe with a high affinity for carbonic anhydrase IX (CAIX), exhibiting a dissociation constant (Kd) of 0.2 nM. It is applicable in studies for visualizing CAIX-positive tumors.</p>Formule :C88H126F3N6NaO24S4Masse moléculaire :1858.75561SH7s
<p>SH7s is an effective carbonic anhydrase inhibitor, exhibiting Ki values of 15.9 nM for hCA IX and 55.2 nM for hCA XII. Additionally, SH7s acts as a hypoxia-mediated chemosensitizer in colorectal cancer cells.</p>Formule :C24H19ClF3N5O4SCouleur et forme :SolidMasse moléculaire :565.95hCA XII-IN-6
<p>Compound 4d, known as hCA XII-IN-6, is a potent inhibitor of human carbonic anhydrase XII (hCA XII) with a Ki value of 84.2 nM and exhibits anti-proliferative</p>Formule :C11H9N5O3S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :323.35Chlorothiazide
CAS :<p>Chlorothiazide (Diuril) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE.</p>Formule :C7H6ClN3O4S2Degré de pureté :98.46% - 98.91%Couleur et forme :Crystals Physical Description Crystals; White Powder (Ntp 1992)Masse moléculaire :295.72Carbonic Anhydrase 12 Protein, Cynomolgus, Recombinant (His)
<p>Carbonic anhydrases (CAs) are a family of enzymes involved in the pH regulation of metabolically active cells/tissues.</p>Couleur et forme :Lyophilized PowderMasse moléculaire :32.04 kDa (predicted). Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.Acetazolamide-d3
CAS :<p>Acetazolamide D3 is a deuterium-labeled Acetazolamide. Acetazolamide is a potent carbonic anhydrase inhibitor.</p>Formule :C4H6N4O3S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :225.26M 12325
CAS :<p>M 12325 is used in the production of furosemide; rhinitis and occupational asthma were observed in workers from a lasamide production line.</p>Formule :C7H5Cl2NO4SCouleur et forme :White To Almost White Solid PowderMasse moléculaire :270.09Brinzolamide hydrochloride
<p>Brinzolamide (AL-4862) HCl selectively inhibits carbonic anhydrase II, reducing IOP for glaucoma research. IC50: 3.2 nM.</p>Couleur et forme :Solid4-(benzyloxy)benzene-1-sulfonamide
CAS :<p>4-(benzyloxy)benzene-1-sulfonamide is inhibitor of human recombinant CA-7.</p>Formule :C13H13NO3SDegré de pureté :97.54%Couleur et forme :SolidMasse moléculaire :263.31Zolamide
CAS :<p>Zolamide (CL 5343) may be used to prevent altitude sickness and reduce the symptoms.</p>Formule :C2H4N4O2S2Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :180.21EMAC10101d
CAS :<p>compound EMAC10101d, bearing a 2,4-dichorophenyl substituent in position 4 of the dihydrothiazole ring, was the most potent and selective toward hCA II with an</p>Formule :C17H15Cl2N3O2S2Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :428.36Benzenesulfonamide
CAS :<p>Benzenesulfonamide (Benzosulfonamide) ia an inhibitor of carbonic anhydrases.</p>Formule :C6H7NO2SDegré de pureté :99.42% - 99.99%Couleur et forme :White Crystalline PowderMasse moléculaire :157.19Dichlorphenamide
CAS :<p>Dichlorphenamide (Diclofenamide) is a carbonic anhydrase inhibitor that is used in the treatment of glaucoma.</p>Formule :C6H6Cl2N2O4S2Degré de pureté :96.87% - 97.25%Couleur et forme :Needles From Dimethylsulfoxide + Water SolidMasse moléculaire :305.16Benzolamide
CAS :<p>Benzolamide (CL 11366) inhibits carbonic anhydrase effectively and low-threshold calcium currents in hippocampal pyramidal neurons.</p>Formule :C8H8N4O4S3Degré de pureté :99.31%Couleur et forme :SolidMasse moléculaire :320.37Dichlorphenamide disodium
CAS :<p>Dichlorphenamide disodium: an oral carbonic anhydrase inhibitor that lowers eye pressure, promising for glaucoma study.</p>Formule :C6H6Cl2N2Na2O4S2Couleur et forme :SolidMasse moléculaire :351.12Dimethylfraxetin
CAS :<p>Dimethylfraxetin (6,7,8-Trimethoxycoumarin) is a Carbonic anhydrase inhibitor(Ki：0.0097 μM)</p>Formule :C12H12O5Degré de pureté :99.96% - ≥95%Couleur et forme :SolidMasse moléculaire :236.224-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide
CAS :<p>4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide (4-Amino-6-(trifluoromethyl)benzene-1,3-d) is a carbonic anhydrase inhibitor, used as a potential anti-</p>Formule :C7H8F3N3O4S2Degré de pureté :98.58%Couleur et forme :SolidMasse moléculaire :319.28Dorzolamide hydrochloride
CAS :<p>Dorzolamide hydrochloride (MK507 hydrochloride) is the hydrochloride salt form of dorzolamide, an inhibitor of carbonic anhydrase, a zinc-containing enzyme that</p>Formule :C10H17ClN2O4S3Degré de pureté :99.48% - 99.67%Couleur et forme :White Off-White Crystalline PowderMasse moléculaire :360.9Methyclothiazide
CAS :<p>Methyclothiazide (Aquatensen) is a substituted benzothiadiazide, used to treat high blood pressure and fluid retention caused by various conditions including</p>Formule :C9H11Cl2N3O4S2Degré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :360.242,3-dihydro-1H-indene-5-sulfonamide
CAS :<p>2,3-dihydro-1H-indene-5-sulfonamide is Carbonic anhydrase 12 (human) inhibitor.</p>Formule :C9H11NO2SDegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :197.25Orthanilamide
CAS :<p>Orthanilamide (Orthanilamide) is a molecule containing the sulfonamide functional group attached to an aniline.</p>Formule :C6H8N2O2SDegré de pureté :99.72% - 99.96%Couleur et forme :White To Pale Cream Crystalline Powder Or CrystalsMasse moléculaire :172.2Indisulam
CAS :<p>Indisulam (E 7070) is a dual-action anticancer drug, blocking G1/S cell cycle transition by degrading cyclin E and activating p53/p21.</p>Formule :C14H12ClN3O4S2Degré de pureté :98.68% - 99.77%Couleur et forme :SolidMasse moléculaire :385.85U-104
CAS :<p>U-104 (NSC-213841) is an effective carbonic anhydrase (CA) inhibitor for CA IX( Ki=45.1 nM) and CA XII(Ki=4.5 nM).</p>Formule :C13H12FN3O3SDegré de pureté :98.76% - 99.88%Couleur et forme :SolidMasse moléculaire :309.32Ethoxzolamide
CAS :<p>Ethoxzolamide (L-643786) is a carbonic anhydrase inhibitor.</p>Formule :C9H10N2O3S2Degré de pureté :98.27% - 99.62%Couleur et forme :Crystals From Ethyl Acetate + Skellysolve B SolidMasse moléculaire :258.32Polmacoxib
CAS :<p>Polmacoxib, a first-class NSAID, dual inhibitor of CA and COX-2, may hinder colorectal cancer growth in mice.</p>Formule :C18H16FNO4SDegré de pureté :97.88%Couleur et forme :SolidMasse moléculaire :361.39Fluorometholone Acetate
CAS :<p>Fluorometholone Acetate (Oxylone acetate) is a synthetic corticosteroid, used in the treatment of steroid responsive inflammatory conditions of the eye.</p>Formule :C24H31FO5Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :418.50GV2-20
CAS :<p>GV2-20 is an effective carbonic anhydrase 2 inhibitors.</p>Formule :C15H13N3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :331.28Disulfamide
CAS :<p>Disulfamide: Oral carbonic anhydrase inhibitor, IC50 0.07 μM, diuretic by blocking Na+/HCO3- reabsorption.</p>Formule :C7H9ClN2O4S2Degré de pureté :98.1%Couleur et forme :SolidMasse moléculaire :284.74HCAIX-IN-2
CAS :<p>HCAIX-IN-2 (compound 9d) is a selective inhibitor of carbonic anhydrase and acts on hCA IX (Ki: 24.6 nM) and hCA XII (Ki: 45.3 nM).</p>Formule :C19H16N8O4SCouleur et forme :SolidMasse moléculaire :452.45hCAIX-IN-11
CAS :<p>hCAIX-IN-11 inhibits carbonic anhydrases IX & XII with Ki of 32.7 nM & 623.5 nM, respectively.</p>Formule :C21H15ClN4O3Couleur et forme :SolidMasse moléculaire :406.82hCAI/II-IN-1
CAS :<p>hCAI/II-IN-1 (Compound 3h) is a human carbonic anhydrase I and II (hCA I/II) inhibitor that acts on hCA I (IC50: 0.047 μM) and hCA II (IC50: 0.024 μM).</p>Formule :C18H29N5O3S3Couleur et forme :SolidMasse moléculaire :459.65hCAIX/XII-IN-2
CAS :<p>Compound 6a: Selective hCAIX/XII inhibitor; Ki: 30 nM (hCAIX), 3.6 nM (hCAXII); >10,000 nM (hCAI/II).</p>Formule :C19H14N2O4Couleur et forme :SolidMasse moléculaire :334.33CDK2-IN-12
CAS :<p>CDK2-IN-12 (10b), potent CDK2 inhibitor, IC50: 11.6 μM; inhibits hCA I/II/IX/XII, KI: 3534/638.4/44.3/48.8 nM; anti-cancer properties.</p>Formule :C20H17N9O2SCouleur et forme :SolidMasse moléculaire :447.47Clofenamide
CAS :<p>Clofenamide is a low-ceiling sulfonamide diuretic.</p>Formule :C6H7ClN2O4S2Couleur et forme :SolidMasse moléculaire :270.71hCAII-IN-2
CAS :<p>hCAII-IN-2 inhibits human carbonic anhydrases I, II, IX, XII with Ki values of 261.4, 3.8, 19.6, 45.2 nM respectively.</p>Formule :C25H18ClN5O4SCouleur et forme :SolidMasse moléculaire :519.96hCAIX/XII-IN-3
CAS :<p>Compound 6q inhibits hCAIX/CAXII; K i : hCAI >10000 nM, hCAII >10000 nM, hCAIX 66.2 nM, hCAXII 4.4 nM.</p>Formule :C20H13F3N2O4Couleur et forme :SolidMasse moléculaire :402.32CDK2-IN-11
CAS :<p>CDK2-IN-11 inhibits CDK2 (IC50: 6.4 μM) and targets hCA II, IX, XII (Ki: 23.4-56.3 nM); suited for cancer research.</p>Formule :C18H14ClN7O2SCouleur et forme :SolidMasse moléculaire :427.87hCA I-IN-1
CAS :<p>hCA I-IN-1 inhibits hCA I (Ki: 38.3 nM), II (Ki: 716.4 nM), IX (Ki: 940.1 nM), XII (Ki: 192.8 nM).</p>Formule :C27H23N5O4SCouleur et forme :SolidMasse moléculaire :513.57hCAXII-IN-3
CAS :<p>hCAXII-IN-3 (Compound 6o) is a selective inhibitor of human carbonic anhydrase XII (hCAXII) (Ki: 10.0 nM).</p>Formule :C26H20BrN5O3SCouleur et forme :SolidMasse moléculaire :562.44Carbonic anhydrase inhibitor 14
CAS :<p>CA inhibitor 14 blocks hCA I/II/IX/XII (K i of 1203/99.7/9.4/27.7 nM) and CDK2 (IC50: 20.3 μM), showing antitumor effects.</p>Formule :C18H17N7O2SCouleur et forme :SolidMasse moléculaire :395.44
