Anhydrase carbonique
L'anhydrase carbonique est une enzyme qui catalyse la conversion réversible du dioxyde de carbone et de l'eau en bicarbonate et protons. Cette enzyme joue un rôle crucial dans le maintien de l'équilibre acido-basique, la respiration et le transport du dioxyde de carbone dans le sang. Les inhibiteurs de l'anhydrase carbonique sont utilisés dans le traitement du glaucome, de l'épilepsie et du mal des montagnes, ainsi que dans la recherche sur l'homéostasie acido-basique et les échanges gazeux. Chez CymitQuimica, nous offrons une gamme d'inhibiteurs de l'anhydrase carbonique et de réactifs de haute qualité pour soutenir vos recherches en enzymologie, physiologie respiratoire et développement thérapeutique.
196 produits trouvés pour "Anhydrase carbonique".
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TSPO/Carbonic Anhydrase Modulator 1
TSPO/Carbonic Anhydrase Modulator 1 (Compound 3) acts as a dual modulator of mitochondrial translocator protein and carbonic anhydrase, with a TSPOKi of 1.340 μM and a CAVII KA of 10.7 μM. It enhances neurosteroid production, increases BDNF gene expression, and demonstrates neuroprotective activity.Formule :C35H51N3O3Couleur et forme :SolidMasse moléculaire :561.798VM4-037
CAS :VM4-037 is a PET imaging agent used for carbonic anhydrase IX.Formule :C26H29FN6O7S2Couleur et forme :SolidMasse moléculaire :620.67hCAII-IN-6
"hCAII-IN-6 (S-13) inhibits hCA II (4.4 nM) and isoforms I, IV, IX (9.2, 480.2, 14.7 nM). For glaucoma research."Formule :C20H25N3O4SCouleur et forme :SolidMasse moléculaire :403.5Phenylsulfamide
CAS :Phenylsulfamide (Compound 10), acting as an inhibitor of human carbonic anhydrase-II (hCA-II), exhibits a dissociation constant (Kd) of 45.50 μM and anFormule :C6H8N2O2SCouleur et forme :SolidMasse moléculaire :172.2Acesulfame
CAS :Acesulfame inhibits CA9/12 and can be used to study inflammation-related diseases.Formule :C4H5NO4SCouleur et forme :SolidMasse moléculaire :163.15hCA/VEGFR-2-IN-4
hCA/VEGFR-2-IN-4 (compound 15b), an indolinylbenzenesulfonamide, serves as a potential dual inhibitor targeting cancer-related human carbonic anhydrases hCA IX/Formule :C22H23FN6O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :502.525,6-Dihydro-2H-pyran-2-one
CAS :5,6-Dihydro-2H-pyran-2-one is a carbonic anhydrase 1/9 inhibitor that inhibits KB cell viability.Formule :C5H6O2Couleur et forme :SolidMasse moléculaire :98.1Carbonic anhydrase inhibitor 30
Carbonic anhydrase inhibitor30 (compound 17) is an inhibitor of carbonic anhydrase with Ki values of 2.13 μM for hCA I and 0.161 μM for hCA II[1].Formule :C23H22FN3O5SCouleur et forme :SolidMasse moléculaire :471.12642hCAII-IN-8
CAS :Compound CDy9 is a highly selective inhibitor of carbonic anhydrase (CA) with an IC50 value of 0.18 μM for hCA II.Formule :C15H16N2O5SDegré de pureté :99.73%Couleur et forme :White SolidMasse moléculaire :336.36Ref: TM-T67774
5mg42,00€1mL*10mM (DMSO)52,00€10mg64,00€25mg116,00€50mg167,00€100mg241,00€200mg339,00€hCAI/II-IN-10
hCAI/II-IN-10 (Compound 5d) is an inhibitor of human carbonic anhydrase I and II (hCA I and hCA II), with IC50 values of 4.32 nM and 3.89 nM, respectively.Formule :C24H17Cl2N3O3S2Couleur et forme :SolidMasse moléculaire :530.446DPP IV/hCA II-IN-1
CAS :DPP IV/hCA II-IN-1: strong DPP IV & CA inhibitor, IC50=0.049μM (DPP IV), Ki=0.0361-3.034μM (CA II-IV).Formule :C17H20N2O5SCouleur et forme :SolidMasse moléculaire :364.42hCA/Wnt/β-catenin-IN-1
hCA/Wnt/β-catenin-IN-1 (Compd 15) serves as an inhibitor with selective affinity for hCA isoforms II, IX, and XII, exhibiting K i values of 33.6, 24.1, and 6.8Couleur et forme :Odour SolidhCAII-IN-7
hCAII-IN-7 (R-13) inhibits human CA I, II, IV, IX with K i of 60.7, 320.7, 2298, 35.2 nM respectively.Formule :C20H25N3O4SCouleur et forme :SolidMasse moléculaire :403.5Carbonic anhydrase inhibitor 32
Carbonic anhydrase inhibitor32 (compound 5B) is an orally active, selective inhibitor of hCA (carbonic anhydrase) II/VII, with Ki values of 6.3 nM for hCA II, 10.1 nM for hCA VII, and 681 nM for hCA I. It shows potential for neuroprotection and anticonvulsant effects by reducing mTOR activation and increasing hippocampal KCC2 levels.Formule :C17H16N6O3SCouleur et forme :SolidMasse moléculaire :384.41CAIX/CAXII-IN-4
CAIX/CAXII-IN-4 (Compound 7h) is an inhibitor of carbonic anhydrase (CA) that binds to CAIX, CA XII, and CAII with Ki values of 1.324 μM, 0.435 μM, and 3.035 μM, respectively. This compound exhibits broad-spectrum anti-tumor activity and inhibits the proliferation of central nervous system tumor cells U251, with a GI50 of 0.361 μM.Formule :C23H21N5O3SCouleur et forme :SolidMasse moléculaire :447.512-Methoxy-4-propylphenol
CAS :2-Methoxy-4-propylphenol is an inhibitor of human carbonic anhydrase isoenzymes 1/2/9/12 and has antifungal activity.Formule :C10H14O2Couleur et forme :SolidMasse moléculaire :166.22hCA/VEGFR-2-IN-2
Compound 8g (hCA/VEGFR-2-IN-2) is an indolinonylbenzenesulfonamide identified as a potential dual inhibitor targeting cancer-associated isozymes hCA IX/XII andFormule :C23H26N6O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :498.55α-Pyrone
CAS :Alpha-Pyrone exhibits inhibitory activity against tyrosinase, carbonic anhydrase 1, and carbonic anhydrase 9Formule :C5H4O2Couleur et forme :SolidMasse moléculaire :96.08DOTA-XYIMSR-01
CAS :DOTA-XYIMSR-01 is a molecular probe targeting CAIX, capable of being labeled with 177Lu for the treatment and localization of malignant gliomas. The uptake of [177Lu]Lu-XYIMSR-01 in U87MG tumors is 6.19% injected dose per gram (% ID/g), with a tumor-to-muscle uptake ratio of 20.14. In an orthotopic glioma model, co-administration with temozolomide significantly enhances survival rates and inhibits tumor growth in mice. DOTA-XYIMSR-01 shows potential for research in the field of cancer treatment.Formule :C61H88N16O22S2Couleur et forme :SolidMasse moléculaire :1461.57Carbonic anhydrase inhibitor 31
Carbonic anhydrase inhibitor31 is an mtCA2 inhibitor (Ki: 5.2 nM) that can be used in antituberculosis research.Formule :C24H20N6O5SCouleur et forme :SolidMasse moléculaire :504.12159
