Anhydrase carbonique
L'anhydrase carbonique est une enzyme qui catalyse la conversion réversible du dioxyde de carbone et de l'eau en bicarbonate et protons. Cette enzyme joue un rôle crucial dans le maintien de l'équilibre acido-basique, la respiration et le transport du dioxyde de carbone dans le sang. Les inhibiteurs de l'anhydrase carbonique sont utilisés dans le traitement du glaucome, de l'épilepsie et du mal des montagnes, ainsi que dans la recherche sur l'homéostasie acido-basique et les échanges gazeux. Chez CymitQuimica, nous offrons une gamme d'inhibiteurs de l'anhydrase carbonique et de réactifs de haute qualité pour soutenir vos recherches en enzymologie, physiologie respiratoire et développement thérapeutique.
196 produits trouvés pour "Anhydrase carbonique".
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Carbonic anhydrase inhibitor 18
Carbonic anhydrase inhibitor18 (Compound 9) is an inhibitor of human carbonic anhydrase (hCA) isozymes, with Ki values of 604.8 nM for hCA I, 333.6 nM for hCA II, 1.9 nM for hCA IX, and 6.7 nM for hCA XII. Carbonic anhydrase inhibitor18 is applicable in cancer research.Formule :C26H28N4O6S2Couleur et forme :SolidMasse moléculaire :556.14503hCAIX-IN-17
hCA IX-IN-1 inhibits hCA I/II/IX/XII with Ki of 331.4/28.4/9.4/17.8 nM, has anticancer properties.Formule :C19H18N2O3SCouleur et forme :SolidMasse moléculaire :354.42VM4-037
CAS :VM4-037 is a PET imaging agent used for carbonic anhydrase IX.Formule :C26H29FN6O7S2Couleur et forme :SolidMasse moléculaire :620.67hCAIX-IN-19
hCAIX-IN-19 is a sulfonamide inhibitor with an inhibition constant (KI) of 6.2 nM for hCAIX, exhibiting significant selectivity towards hCAIX over hCAI (hCA I/Couleur et forme :Odour SolidAcesulfame
CAS :Acesulfame inhibits CA9/12 and can be used to study inflammation-related diseases.Formule :C4H5NO4SCouleur et forme :SolidMasse moléculaire :163.15hCA/Wnt/β-catenin-IN-1
hCA/Wnt/β-catenin-IN-1 (Compd 15) serves as an inhibitor with selective affinity for hCA isoforms II, IX, and XII, exhibiting K i values of 33.6, 24.1, and 6.8Couleur et forme :Odour SolidCarbonic anhydrase inhibitor 29
Carbonic anhydrase inhibitor29 (Compound 5d) is an inhibitor targeting carbonic anhydrase IX and XII, with an inhibition constant (Ki) of 26.6 nM for carbonic anhydrase IX and a Ki of 10.9 nM for carbonic anhydrase XII. Carbonic anhydrase inhibitor29 can be used in cancer research.Couleur et forme :Odour SolidCAXII-IN-2
CAXII-IN-2 (compound 3j) is a highly effective inhibitor of CAXII. It demonstrates inhibitory activity against CA IX and CAXII, with Ki values of 27.4 nM and 4.0 nM, respectively.Formule :C16H13FNO4PCouleur et forme :SolidMasse moléculaire :333.05662hCAIX/XII-IN-11
hCAIX/XII-IN-11 (Compound 6c) is an inhibitor of hCA IX and hCA XII, exhibiting Ki values of 0.7 μM for both isoforms. This compound is applicable in cancer research.Formule :C13H10FN3O4Couleur et forme :SolidMasse moléculaire :291.06553GZ22-4
GZ22-4 is a near-infrared (NIR) fluorescent probe with a high affinity for carbonic anhydrase IX (CAIX), exhibiting a dissociation constant (Kd) of 0.2 nM. It is applicable in studies for visualizing CAIX-positive tumors.Formule :C88H126F3N6NaO24S4Couleur et forme :SolidMasse moléculaire :1858.75561Girentuximab
CAS :Girentuximab (G250) is an anti-carbonic anhydrase IX (CAIX) monoclonal antibody with anti-cancer activity for the study of uroepithelial carcinoma PET (ZiPUP).Couleur et forme :Transparent LiquidMasse moléculaire :145.55 kDaBendroflumethiazide
CAS :Bendroflumethiazide (Naturetin) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)Formule :C15H14F3N3O4S2Degré de pureté :98% - >99.99%Couleur et forme :White SolidMasse moléculaire :421.41hCA XII-IN-6
Compound 4d, known as hCA XII-IN-6, is a potent inhibitor of human carbonic anhydrase XII (hCA XII) with a Ki value of 84.2 nM and exhibits anti-proliferativeFormule :C11H9N5O3S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :323.35α-Pyrone
CAS :Alpha-Pyrone exhibits inhibitory activity against tyrosinase, carbonic anhydrase 1, and carbonic anhydrase 9Formule :C5H4O2Couleur et forme :SolidMasse moléculaire :96.08Carbonic Anhydrase 12 Protein, Cynomolgus, Recombinant (His)
Carbonic anhydrases (CAs) are a family of enzymes involved in the pH regulation of metabolically active cells/tissues.Couleur et forme :Lyophilized PowderMasse moléculaire :32.04 kDa (predicted). Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.Trichlormethiazide (Standard)
CAS :Trichlormethiazide (Standard) is the standard substance of Trichlormethiazide, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Trichlormethiazide (Naqua) is a short-acting, 3-dichloromethyl derivative of hydrochlorothiazide, belonging to the class of thiazide diuretics. Trichlormethiazide appears to block the active reabsorption of chloride and possibly sodium in the ascending loop of Henle, altering electrolyte transfer in the proximal tubule.Formule :C8H8Cl3N3O4S2Couleur et forme :SolidMasse moléculaire :380.66Acetazolamide-D3
CAS :Acetazolamide D3 is a deuterium-labeled Acetazolamide. Acetazolamide is a potent carbonic anhydrase inhibitor.Formule :C4H6N4O3S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :225.264-Chloro-3-sulfamoylbenzoic acid
CAS :4-Chloro-3-sulfamoylbenzoic acid ,with CAS No. 1205-30-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-Chloro-3-sulfamoylbenzoic acid provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formule :C7H6ClNO4SCouleur et forme :SolidMasse moléculaire :235.64M 12325
CAS :M 12325 is used in the production of furosemide; rhinitis and occupational asthma were observed in workers from a lasamide production line.Formule :C7H5Cl2NO4SCouleur et forme :SolidMasse moléculaire :270.09Zolamide
CAS :Zolamide (CL 5343) may be used to prevent altitude sickness and reduce the symptoms.Formule :C2H4N4O2S2Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :180.21
