Synthase des acides gras
La synthase des acides gras (FAS) est un complexe multi-enzymatique responsable de la synthèse des acides gras à longue chaîne. La surexpression de FAS est associée à divers troubles métaboliques, notamment l'obésité, le diabète et le cancer. L'inhibition de FAS peut réduire la biosynthèse des lipides et induire l'apoptose des cellules cancéreuses, ce qui en fait une cible prometteuse pour la thérapie contre le cancer et la recherche sur les maladies métaboliques. Chez CymitQuimica, nous proposons une variété d'inhibiteurs de FAS pour soutenir vos recherches en oncologie, métabolisme et développement thérapeutique.
32 produits trouvés pour "Synthase des acides gras"
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FASN-IN-3
CAS :<p>FASN-IN-3 is an inhibitor of fatty acid synthase (FASN).</p>Formule :C24H24N4ODegré de pureté :97.41%Couleur et forme :SolidMasse moléculaire :384.47Denifanstat
CAS :<p>Denifanstat (FASN-IN-2) is a FASN inhibitor with selective and oral activity. Denifanstat has been used in studies of steatohepatitis. Cost effective and quality assured.</p>Formule :C27H29N5ODegré de pureté :98.33% - 99.35%Couleur et forme :SolidMasse moléculaire :439.55PF429242 dihydrochloride
CAS :<p>PF429242 dihydrochloride can reversibly inhibit S1P (IC50 of 175 nM).</p>Formule :C25H37Cl2N3O2Degré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :482.49trans-C75
CAS :<p>trans-C75 ((±)-C75) is an enantiomer of C75. C75 is an inhibitor of fatty-acid synthase (FASN).</p>Formule :C14H22O4Degré de pureté :98.88% - 99.57%Couleur et forme :White To Off-White SolidMasse moléculaire :254.32CTL-12
<p>CTL-12, a fatty acid synthase (FASN) inhibitor (IC50: 2.5 μM), induces apoptosis and disrupts the cell cycle at the Sub-G1/S phase.</p>Formule :C22H21ClN4O4Couleur et forme :SolidMasse moléculaire :440.88Betulin ditosylate
CAS :<p>Betulinditosylate is a derivative of Betulin, which functions as an SREBP inhibitor.</p>Formule :C44H62O6S2Couleur et forme :SolidMasse moléculaire :751.09IPI-9119
CAS :<p>IPI-9119 is an orally active, selective and irreversible FASN inhibitor (IC50 = 0.3 nM).</p>Formule :C24H19F2N5O5Degré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :495.43FASN-IN-4 tosylate
CAS :<p>FASN-IN-4 tosylate: Fatty acid synthase inhibitor, IC50 10 nM; blocks SARS-CoV-2, EC50 18.6 nM.</p>Formule :C33H35N3O7S2Couleur et forme :SolidMasse moléculaire :649.78Fasnall HCl
<p>Fasnall HCl is a selective FASN inhibitor that acts through its co-factor binding sites.</p>Formule :C19H23ClN4SDegré de pureté :99.9%Couleur et forme :SoildMasse moléculaire :374.93CTL-06
<p>CTL-06, a Fatty Acid Synthase (FASN) inhibitor with an IC50 of 3 μM, induces apoptosis, while CTL-12 impedes cell cycle progression in the Sub-G1/S phase and</p>Formule :C21H21ClN4O4Couleur et forme :SolidMasse moléculaire :428.87ACSS2-IN-2
CAS :<p>MTB-9655 inhibits ACSS2 with 3.8 nM IC50, useful in research of viral, metabolic, neuropsychiatric diseases, inflammation, and cancer.</p>Formule :C21H19F2N3O4Degré de pureté :99.5%Couleur et forme :SoildMasse moléculaire :415.39Lipid Metabolism Compound Library
<p>A unique collection of 492 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS).</p>Couleur et forme :Odour SolidFASN Protein, Human, Recombinant (His)
<p>FASN Protein, Human, Recombinant (His) is expressed in E.</p>Couleur et forme :Lyophilized PowderMasse moléculaire :35.26 kDa (predicted)Anti-FASN Antibody (6U56)
<p>Anti-FASN Antibody (6U56) is an antibody targeting FASN. Anti-FASN Antibody (6U56) can be used in ELISA, IF, FCM.</p>Couleur et forme :Odour LiquidBI 99179
CAS :<p>BI 99179 is a selective and potent inhibitor of type I fatty acid synthase (FAS), a tool compound for targeting FAS for cancer research.</p>Formule :C23H25N3O3Degré de pureté :98.73%Couleur et forme :SolidMasse moléculaire :391.46FASN Protein, Mouse, Recombinant (His)
<p>FASN Protein, Mouse, Recombinant (His) is expressed in E.</p>Degré de pureté :≥ 95 % as determined by SDS-PAGE. - ≥ 95 % as determined by SDS-PAGE.Couleur et forme :Lyophilized PowderMasse moléculaire :34.23 kDa (predicted)VY-3-135
CAS :<p>VY-3-135 is an orally active, stable and specific acetyl-CoA synthetase 2 (ACSS2) inhibitor.Cost-effective and quality-assured.</p>Formule :C26H27N3O3Degré de pureté :99.25% - 99.79%Couleur et forme :SolidMasse moléculaire :429.51FT113
CAS :<p>FT113 is a novel potent inhibitor of fatty acid synthase (fasn, IC50 : 213 nM),and exhibits anti-cancer activity</p>Formule :C22H20FN3O4Degré de pureté :97.05%Couleur et forme :SolidMasse moléculaire :409.41TVB-3664
CAS :<p>TVB-3664 is an orally active, selective, highly bioavailable fatty acid synthase inhibitor (FASN).Cost-effective and quality-assured.</p>Formule :C25H23F3N4O2Degré de pureté :99.17% - 99.64%Couleur et forme :SolidMasse moléculaire :468.47PF 429242
CAS :<p>PF-429242 inhibits SREBP site 1 protease selectively (IC50: 0.175 μM); reduces cholesterol synthesis in CHO cells (IC50: 0.53 μM).</p>Formule :C25H35N3O2Degré de pureté :99.27%Couleur et forme :SolidMasse moléculaire :409.56Fas C-Terminal Tripeptide Acetate
<p>Fas C-Terminal Tripeptide Acetate shows inhibitory activity of Fas/FAP-1 binding.</p>Formule :C18H33N3O8Degré de pureté :99.12%Couleur et forme :SolidMasse moléculaire :419.47HS79
CAS :<p>HS-79, a Fasnall enantiomer, selectively inhibits FASN with an IC50 of 1.57 μM, blocking tritiated acetate lipid incorporation.</p>Formule :C19H22N4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :338.47HS80
CAS :<p>HS-80, a Fasnall enantiomer, selectively inhibits FASN, blocking lipid synthesis (IC50: 7.13 μM).</p>Formule :C19H22N4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :338.47FASN-IN-5
CAS :<p>FASN-IN-5 is a FASN inhibitor, useful for studying cancer and metabolic diseases.</p>Formule :C29H26N4O2Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :462.54FASN-IN-4
CAS :<p>FAS-IN-1 is a potent inhibitor of Fatty acid synthase (FAS) wtih IC50 of 10 nM.</p>Formule :C26H27N3O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :477.58C75
CAS :<p>C75 is an inhibitor synthetic fatty-acid synthase (FASN) and inhibits prostate cancer cells PC3 (IC50: 35 μM).</p>Formule :C14H22O4Degré de pureté :98.84% - >99.99%Couleur et forme :SolidMasse moléculaire :254.32Malic enzyme inhibitor ME1
CAS :<p>Malic enzyme inhibitor ME1 (ME1) is a specific inhibitor of Malic enzyme (IC50 = 0.15 μM). Malic enzyme inhibitor ME1 reduces cell viability/metabolic activity.</p>Formule :C20H21N3O3Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :351.4FASN-IN-1
CAS :<p>FASN-in-1 is an effective, specific inhibitor of fatty acid synthase (FASN), a compound specifically designed to target and inhibit the activity of the enzyme</p>Formule :C18H25N3O3S2Degré de pureté :99.92% - >99.99%Couleur et forme :SolidMasse moléculaire :395.54SREBP/SCAP-IN-2
CAS :<p>SREBP/SCAP-IN-2 (compound 13) acts as a selective inhibitor of SREBP/SCAP [1].</p>Formule :C27H37ClF2N4OCouleur et forme :SolidMasse moléculaire :507.06SREBP/SCAP-IN-1
CAS :<p>SREBP/SCAP-IN-1 (compound 10b) serves as a selective inhibitor of SREBP/SCAP [1].</p>Formule :C28H40F2N4OCouleur et forme :SolidMasse moléculaire :486.64FAS-IN-1 Tosylate
<p>FAS-IN-1 Tosylate is an effective fatty acid synthase inhibitor;Has an IC50 of 10 nM.</p>Formule :C33H35N3O7S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :649.78PFM046
CAS :<p>PFM046 is an antagonist of the liver X receptor (LXR), effectively inhibiting the activation of LXRα and LXRβ, with IC50 values of 2.04 μM and 1.58 μM respectively. It reduces the expression of SCD1 and FASN while increasing ABCA1 expression, and demonstrates antitumor activity in mouse models.</p>Formule :C29H42O2Couleur et forme :SolidMasse moléculaire :422.643
