Synthase des acides gras
La synthase des acides gras (FAS) est un complexe multi-enzymatique responsable de la synthèse des acides gras à longue chaîne. La surexpression de FAS est associée à divers troubles métaboliques, notamment l'obésité, le diabète et le cancer. L'inhibition de FAS peut réduire la biosynthèse des lipides et induire l'apoptose des cellules cancéreuses, ce qui en fait une cible prometteuse pour la thérapie contre le cancer et la recherche sur les maladies métaboliques. Chez CymitQuimica, nous proposons une variété d'inhibiteurs de FAS pour soutenir vos recherches en oncologie, métabolisme et développement thérapeutique.
37 produits trouvés pour "Synthase des acides gras"
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Ac-CoA Synthase Inhibitor1
CAS :Ac-CoA Synthase Inhibitor1 (ACSS2 inhibitor) is the most potent and specific inhibitor of acetate-dependent acetyl-CoA synthetase 2 (ACSS2).Formule :C20H18N4O2S2Degré de pureté :99.26% - 99.84%Couleur et forme :SolidMasse moléculaire :410.51PF 429242
CAS :PF-429242 inhibits SREBP site 1 protease selectively (IC50: 0.175 μM); reduces cholesterol synthesis in CHO cells (IC50: 0.53 μM).Formule :C25H35N3O2Degré de pureté :99.27%Couleur et forme :SolidMasse moléculaire :409.56Ref: TM-T4317
1mg44,00€2mg55,00€5mg99,00€1mL*10mM (DMSO)99,00€10mg173,00€25mg384,00€50mg560,00€100mg817,00€TVB-3664
CAS :TVB-3664 is an orally active, selective, highly bioavailable fatty acid synthase inhibitor (FASN).Cost-effective and quality-assured.Formule :C25H23F3N4O2Degré de pureté :99.17% - 99.64%Couleur et forme :SolidMasse moléculaire :468.47Ref: TM-T17181
1mg114,00€5mg268,00€1mL*10mM (DMSO)294,00€10mg432,00€25mg708,00€50mg1.044,00€100mg1.423,00€Fatostatin
CAS :Fatostatin inhibits SREBP-1/2 by binding to SCAP, blocking their ER-Golgi transport.Formule :C18H18N2SDegré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :294.41Ref: TM-T9266
2mg34,00€5mg48,00€1mL*10mM (DMSO)50,00€10mg70,00€25mg112,00€50mg182,00€100mg309,00€200mg465,00€HS80
CAS :HS-80, a Fasnall enantiomer, selectively inhibits FASN, blocking lipid synthesis (IC50: 7.13 μM).Formule :C19H22N4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :338.47FASN-IN-5
CAS :FASN-IN-5 is a FASN inhibitor, useful for studying cancer and metabolic diseases.Formule :C29H26N4O2Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :462.54FASN-IN-4
CAS :FAS-IN-1 is a potent inhibitor of Fatty acid synthase (FAS) wtih IC50 of 10 nM.Formule :C26H27N3O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :477.58HS79
CAS :HS-79, a Fasnall enantiomer, selectively inhibits FASN with an IC50 of 1.57 μM, blocking tritiated acetate lipid incorporation.Formule :C19H22N4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :338.47C75
CAS :C75 is an inhibitor synthetic fatty-acid synthase (FASN) and inhibits prostate cancer cells PC3 (IC50: 35 μM).Formule :C14H22O4Degré de pureté :98.84% - >99.99%Couleur et forme :SolidMasse moléculaire :254.32Ref: TM-T10657
1mg46,00€2mg62,00€5mg92,00€1mL*10mM (DMSO)101,00€10mg154,00€25mg299,00€50mg477,00€100mg757,00€Malic enzyme inhibitor ME1
CAS :Malic enzyme inhibitor ME1 (ME1) is a specific inhibitor of Malic enzyme (IC50 = 0.15 μM). Malic enzyme inhibitor ME1 reduces cell viability/metabolic activity.Formule :C20H21N3O3Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :351.4Ref: TM-T11940
1mg73,00€1mL*10mM (DMSO)157,00€5mg188,00€10mg344,00€25mg585,00€50mg833,00€100mg1.121,00€500mg2.270,00€SREBP/SCAP-IN-2
CAS :SREBP/SCAP-IN-2 (compound 13) acts as a selective inhibitor of SREBP/SCAP [1].Formule :C27H37ClF2N4OCouleur et forme :SolidMasse moléculaire :507.061,3-Dipalmitoyl-2-Docosahexaenoyl Glycerol
CAS :1,3-Dipalmitoyl-2-docosahexaenoyl glycerol, a triacylglycerol, features palmitic acid at the sn-1 and sn-3 positions and docosahexaenoic acid at the sn-2 position. Its dietary administration (30 g/kg) has been shown to decrease hepatic triglyceride and cholesterol levels in mice.Formule :C57H98O6Couleur et forme :SolidMasse moléculaire :879.38FAS-IN-1 Tosylate
FAS-IN-1 Tosylate is an effective fatty acid synthase inhibitor;Has an IC50 of 10 nM.
Formule :C33H35N3O7S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :649.78SREBP/SCAP-IN-1
CAS :SREBP/SCAP-IN-1 (compound 10b) serves as a selective inhibitor of SREBP/SCAP [1].Formule :C28H40F2N4OCouleur et forme :SolidMasse moléculaire :486.64FASN-IN-1
CAS :FASN-in-1 is an effective, specific inhibitor of fatty acid synthase (FASN), a compound specifically designed to target and inhibit the activity of the enzymeFormule :C18H25N3O3S2Degré de pureté :99.92% - >99.99%Couleur et forme :SolidMasse moléculaire :395.54PFM046
CAS :PFM046 is an antagonist of the liver X receptor (LXR), effectively inhibiting the activation of LXRα and LXRβ, with IC50 values of 2.04 μM and 1.58 μM respectively. It reduces the expression of SCD1 and FASN while increasing ABCA1 expression, and demonstrates antitumor activity in mouse models.Formule :C29H42O2Couleur et forme :SolidMasse moléculaire :422.643ONL-1204
CAS :ONL-1204 is a small molecule, CD95 antigen inhibitor (Fas inhibitor) being developed by ONL Therapeutics for the treatment of retinal detachment.Formule :C71H100N18O16Couleur et forme :SolidMasse moléculaire :1461.66
