Déshydrogénase
Les déshydrogénases sont des enzymes impliquées dans les réactions d'oxydoréduction des voies métaboliques, jouant un rôle central dans la production d'énergie et la respiration cellulaire. Ces enzymes sont cruciales pour des processus tels que le cycle de l'acide citrique, la glycolyse et l'oxydation des acides gras. Les inhibiteurs de déshydrogénases sont des outils importants dans l'étude des maladies métaboliques, du cancer et du stress oxydatif. Chez CymitQuimica, nous proposons une sélection complète d'inhibiteurs de déshydrogénases pour soutenir vos recherches en métabolisme, biologie du cancer et biochimie.
267 produits trouvés pour "Déshydrogénase"
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PDK-IN-1
CAS :<p>PDK-IN-1, a PDK inhibitor, IC50: 0.03μM (PDK1), 0.1μM (HSP90), reduces tumor mass.</p>Formule :C20H16BrN7OCouleur et forme :SolidMasse moléculaire :450.29MCI-INI-3
CAS :<p>MCI-INI-3 is a selective competitive inhibitor of human ALDH1A3, with a Ki value of 0.55 μM for ALDH1A3 and 78.2 μM for ALDH1A1. It inhibits retinoic acid biosynthesis and can reduce the viability of glioblastoma cells GSC-83 and GSC-326.</p>Formule :C21H15N3O4Couleur et forme :SolidMasse moléculaire :373.36BMS-770767
CAS :<p>BMS-770767 is a novel 11-betahydroxysteroid dehydrogenase type I (11ß-HSD1) inhibitor.</p>Formule :C19H18ClN3O2Couleur et forme :SolidMasse moléculaire :355.82SW209049
CAS :<p>SW209049 is a stearoyl-CoA 9-desaturase inhibitor. SW209049 exhivits potent activity against H2122 cell with IC50 of 0.13uM.</p>Formule :C25H18N2O4SDegré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :442.49DSM1465
<p>DSM1465 (Compound 82) is a potent and selective inhibitor of P. falciparum dihydroorotate dehydrogenase (PfDHODH) with an IC50 value of 15 nM. It inhibits P. falciparum 3D7 (Pf3D7) parasites with an EC50 value of 1.4 nM and demonstrates significant in vivo efficacy in humanized P. falciparum mouse models.</p>Formule :C17H12ClF6N5O2Couleur et forme :SolidMasse moléculaire :467.75317β-HSD10-IN-1
CAS :<p>17β-HSD10-IN-1 is a 17β-hydroxysteroid dehydrogenase type 10 inhibitor with blood-brain permeability and potency for the study of Alzheimer's disease.</p>Formule :C16H13ClN4O3SDegré de pureté :98.47%Couleur et forme :SoildMasse moléculaire :376.82Osmanthuside H
CAS :<p>Osmanthuside H is a useful organic compound for research related to life sciences. The catalog number is T125796 and the CAS number is 149155-70-4.</p>Formule :C19H28O11Couleur et forme :SolidMasse moléculaire :432.422PDK-IN-2
<p>PDK-IN-2 (Compound 1F), with an IC50 of 68 nM, is a potent PDK inhibitor that downregulates the expression of PDK1 and PDK4 in cells.</p>Formule :C17H23AsCl2N2O2S2Couleur et forme :SolidMasse moléculaire :497.33MTHFD2-IN-4
<p>MTHFD2-IN-4, a tricyclic coumarin derivative, serves as a potent inhibitor of MTHFD2 and has applications in cancer research [1].</p>Formule :C26H21F6N2O5Couleur et forme :SolidMasse moléculaire :555.45Diethanolamine hydrochloride
CAS :<p>Diethanolamine hydrochloride is HSD17B4 (hydroxysteroid 17-beta dehydrogenase 4) and pregnane X receptor (PXR), p53 Estrogen receptor.</p>Formule :C4H12ClNO2Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :141.6D-Lactate dehydrogenase
CAS :<p>D-LDH is an oxidoreductase turning D-lactate into pyruvate, using NAD+/NADP+; prevalent in bacteria and fungi, key for biochemical research.</p>Couleur et forme :SolidhDHODH-IN-13
CAS :<p>hDHODH-IN-13 (compound w2), an inhibitor of human dihydroorotate dehydrogenase (hDHODH), exhibits an IC50 of 173.4 nM and has potential research applications in</p>Couleur et forme :SoildOctanoyl Coenzyme A (sodium salt)
<p>Octanoyl Coenzyme A (sodium salt) inhibits citrate synthase and glutamate dehydrogenase with an IC50 of 0.4–1.6 mM.</p>Formule :C29H49N7NaO17P3SCouleur et forme :SolidMasse moléculaire :915.7111β-HSD1 inibitor 19
CAS :<p>3-chloro-4-sulfonyl-Benzonitrile inhibits hHSD1/mHSD1, IC50: 16nM/10nM.</p>Formule :C19H16ClF4N3O2SDegré de pureté :99.58%Couleur et forme :SoildMasse moléculaire :461.86MTHFD2-IN-4 sodium
<p>MTHFD2-IN-4 sodium, a potent inhibitor of MTHFD2 and a tricyclic coumarin derivative, is applicable in cancer research [1].</p>Formule :C26H21F6N2NaO5Couleur et forme :SolidMasse moléculaire :578.44DHODH-IN-23
CAS :<p>DHODH-IN-23 is a DHODH inhibitor with oral activity. DHODH-IN-23 is often used in cancer research.</p>Formule :C24H21ClFNO4Degré de pureté :99.7%Couleur et forme :SolidMasse moléculaire :441.88DHODH-IN-16
CAS :<p>DHODH-IN-16 is an effective inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 0.396 nM for human).</p>Formule :C24H25FN4O3Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :436.48Antiproliferative agent-13
CAS :<p>Antiproliferative agent-13 is a compound with antiproliferative activity.</p>Formule :C20H18N2O6Degré de pureté :99.723%Couleur et forme :SolidMasse moléculaire :382.37DSM705
CAS :<p>DSM705: Pyrrole-based, potent nanomolar Plasmodium DHODH inhibitor with strong antimalarial efficacy; spares mammalian DHODH.</p>Formule :C19H19F3N6OCouleur et forme :SolidMasse moléculaire :404.397Aldehyde dehydrogenase (NAD(P))
CAS :<p>ALDH catalyzes oxidation of aldehydes to acids, reducing NAD(P) to NAD(P)H, helping alleviate aldehyde stress.</p>Couleur et forme :SolidALDH1A2-IN-1
CAS :<p>ALDH1A2-IN-1 is a reversible active-site-directed ALDH1A2 inhibitor preventing spermatogenesis, useful in male contraceptive research.</p>Formule :C21H26N4O4SDegré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :430.52Ketogestin
CAS :<p>Ketogestin is a progestational steroid and an inhibitor of enzyme 11β-hydroxysteroid dehydrogenase, and a weak negative modulator of GABAA receptors.</p>Formule :C21H28O3Degré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :328.45PKUMDL-WQ-2201
CAS :<p>PKUMDL-WQ-2201 is a selective allosteric inhibitor of phosphoglycerate dehydrogenase (PHGDH) with Anti-tumor Activity, it binds to site II.</p>Formule :C15H14ClN3O3SCouleur et forme :SolidMasse moléculaire :351.81DSM265
CAS :<p>DSM265 (PfSPZ) is a dihydroorotic acid dehydrogenase inhibitor with antimalarial activity.DSM265 can be used for the treatment of malaria infections.</p>Formule :C14H12F7N5SDegré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :415.332-Bromoacetamide
CAS :<p>2-Bromoacetamide (α-Bromoacetamide) is a class of disinfection by-products that exhibit developmental toxicity in animals.</p>Formule :C2H4BrNODegré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :137.96ALDH1A3-IN-1
CAS :<p>ALDH1A3-IN-1 (Compound 14) is a potent inhibitor of ALDH1A3 which can be used in prostate cancer research (IC50 = 0.63 μM; Ki = 0.46 μM) [1].</p>Formule :C13H18BrNOCouleur et forme :SolidMasse moléculaire :284.19DSM502
CAS :<p>DSM502 DSM502 is a dihydroorotic acid dehydrogenase (DHODH) inhibitor with antimalarial activity that inhibits Plasmodium DHODH and can be used as a lead for antimalarial compounds.</p>Formule :C16H16F3N3ODegré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :323.31ALDH3A1-IN-1
CAS :<p>ALDH3A1-IN-1 (Compound 18) is a potent inhibitor of ALDH3A1 with IC50 of 1.61 μM, outperforms DEAB in prostate cancer cells.</p>Formule :C13H18N2O3Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :250.29ABT-384
CAS :<p>ABT-384 is a high-affinity, selective 11β-HSD1 inhibitor capable of suppressing hepatic and central nervous system HSD-1 activity for depressive disorder.</p>Formule :C25H34F3N5O2Degré de pureté :99.863%Couleur et forme :SolidMasse moléculaire :493.584-Isopropoxybenzaldehyde
CAS :<p>ALDH1A3-IN-3 inhibits ALDH1A3 (IC50: 0.26 μM), acts on ALDH3A1, and is used in prostate cancer research.</p>Formule :C10H12O2Degré de pureté :99.00%Couleur et forme :SolidMasse moléculaire :164.2Brequinar
CAS :<p>Brequinar (NSC-368390) is a potent inhibitor of dihydroorotate dehydrogenase, with potent activities against a broad spectrum of viruses.</p>Formule :C23H15F2NO2Degré de pureté :99.1% - 99.57%Couleur et forme :SolidMasse moléculaire :375.37BVT 2733
CAS :<p>BVT 2733 is a new, non-steroidal, isoform-specific inhibitor of 11β-HSD1.</p>Formule :C17H21ClN4O3S2Degré de pureté :98% - 99.64%Couleur et forme :SolidMasse moléculaire :428.96Vidofludimus hemicalcium
CAS :Vidofludimus hemicalcium: oral DHODH inhibitor, FXR modulator, for autoimmune and fatty liver research.Formule :C20H18FNO4CaCouleur et forme :SolidMasse moléculaire :375.4AGI-6780
CAS :<p>AGI-6780 is a potent and selective inhibitor of IDH2 R140Q mutant.</p>Formule :C21H18F3N3O3S2Degré de pureté :98.19% - 99.7%Couleur et forme :SolidMasse moléculaire :481.51Mutant IDH1-IN-1
CAS :<p>Mutant IDH1-IN-1 is a potent mutant IDH1 R132 h inhibitor with IC50 < 0.1 uM.</p>Formule :C30H31FN4O2Degré de pureté :99.49% - >99.99%Couleur et forme :SolidMasse moléculaire :498.59(E/Z)-Teriflunomide
CAS :<p>(E/Z)-Teriflunomide (Aubagio), a orally-available Pyrimidine Synthesis Inhibitor, is used to treat relapsing multiple sclerosis.</p>Formule :C12H9F3N2O2Degré de pureté :99.49% - 99.76%Couleur et forme :White SolidMasse moléculaire :270.21Nitrofurazone
CAS :<p>Nitrofurazone (Furacilin) is a topical anti-infective agent effective against gram-negative and gram-positive bacteria.</p>Formule :C6H6N4O4Degré de pureté :99.87%Couleur et forme :Pale Yellow Needles Solution) 6 0 - 6 5 Alkaline Solutions Are Dark Orange (Ntp 1992)Masse moléculaire :198.14NCT-503
CAS :<p>NCT-503 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor with no activity against other dehydrogenases. NCT-503 has antitumor activity. Cost-effective and quality-assured.</p>Formule :C20H23F3N4SDegré de pureté :98.91% - 99.84%Couleur et forme :SolidMasse moléculaire :408.48L-Allylglycine
CAS :<p>L-Allylglycine is a potent inhibitor of the synthetic enzyme for GABA, glutamic acid decarboxylase.</p>Formule :C5H9NO2Degré de pureté :≥98%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :115.13R162
CAS :<p>R162 is an effective glutamate dehydrogenase 1 (GDH1) inhibitor.</p>Formule :C17H12O3Degré de pureté :96.21% - 98.15%Couleur et forme :SolidMasse moléculaire :264.28PfDHODH-IN-2
CAS :<p>PfDHODH-IN-2: powerful antimalarial, blocks PfDHODH (IC50: 1.11 μM), for malaria research.</p>Formule :C13H12ClNO3SDegré de pureté :98.9%Couleur et forme :SolidMasse moléculaire :297.76VER-246608
CAS :<p>VER-246608 inhibits PDK (IC50: 35-91 nM), boosts PDC, reduces glycolysis, causes cancer cell cytostasis, and enhances doxorubicin effects.</p>Formule :C28H23ClF2N4O4Degré de pureté :98.5%Couleur et forme :SolidMasse moléculaire :552.96NCT-505
CAS :<p>NCT-505 is a potent and selective inhibitor of aldehyde dehydrogenase (ALDH1A1, IC50 = 7 nM) and a weak inhibitor of hALDH1A2, hALDH1A3, hALDH2, hALDH3A1 with</p>Formule :C27H28FN5O3SDegré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :521.61BI-187004
CAS :<p>BI-187004 is an 11β-hydroxysteroid dehydrogenase 1 inhibitor.</p>Formule :C21H18N4ODegré de pureté :98.63%Couleur et forme :SolidMasse moléculaire :342.39NCT-501 hydrochloride
CAS :<p>NCT-501 hydrochloride: potent, selective ALDH1A1 inhibitor based on theophylline; IC50 of 40 nM; highly discriminant against other ALDHs.</p>Formule :C21H33ClN6O3Couleur et forme :SolidMasse moléculaire :452.98Galloflavin
CAS :<p>Galloflavin is a lactate dehydrogenase inhibitor. Galloflavin inhibits both human LDH isoforms (type A and type B).Cost-effective and quality-assured.</p>Formule :C12H6O8Degré de pureté :96.24% - 97.47%Couleur et forme :SolidMasse moléculaire :278.17CM10
CAS :<p>CM10 is an aldehyde dehydrogenase 1A family(ALDH1A) inhibitor.</p>Formule :C20H23N3ODegré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :321.42DS-1001b
CAS :<p>DS-1001b is an inhibitor of mutant IDH-1 (Isocitrate Dehydrogenase-1)</p>Formule :C29H29Cl3FN3O4Degré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :608.92Perfluorooctanoic acid
CAS :<p>Perfluorooctanoic acid (PFOA) (PFOA) is a persistent and widespread industry-made chemical.</p>Formule :C8HF15O2Degré de pureté :99.70%Couleur et forme :White To Off-White Powder OthersolidMasse moléculaire :414.07G6PDi-1
CAS :<p>G6PDi-1 is an effective G6PD inhibitor. It depletes NADPH and decreases inflammatory cytokine production.</p>Formule :C14H12N4OSDegré de pureté :98.69%Couleur et forme :SolidMasse moléculaire :284.34
