Déshydrogénase
Les déshydrogénases sont des enzymes impliquées dans les réactions d'oxydoréduction des voies métaboliques, jouant un rôle central dans la production d'énergie et la respiration cellulaire. Ces enzymes sont cruciales pour des processus tels que le cycle de l'acide citrique, la glycolyse et l'oxydation des acides gras. Les inhibiteurs de déshydrogénases sont des outils importants dans l'étude des maladies métaboliques, du cancer et du stress oxydatif. Chez CymitQuimica, nous proposons une sélection complète d'inhibiteurs de déshydrogénases pour soutenir vos recherches en métabolisme, biologie du cancer et biochimie.
267 produits trouvés pour "Déshydrogénase"
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Carbenoxolone disodium
CAS :<p>Carbenoxolone disodium treats stomach ulcers; derived from licorice, often has antidiuretic effects, low toxicity.</p>Formule :C34H48Na2O7Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :614.72MK-8245
CAS :<p>MK-8245 is a liver-targeting SCD inhibitor for human SCD1 (IC50: 1 nM) and for rat/mouse SCD1 (IC50: 3 nM), with anti-diabetic and anti-dyslipidemic function.</p>Formule :C17H16BrFN6O4Degré de pureté :97.58% - 99%Couleur et forme :SolidMasse moléculaire :467.25NCT-501 hydrochloride
CAS :<p>NCT-501 hydrochloride: potent, selective ALDH1A1 inhibitor based on theophylline; IC50 of 40 nM; highly discriminant against other ALDHs.</p>Formule :C21H33ClN6O3Couleur et forme :SolidMasse moléculaire :452.98Vidofludimus hemicalcium
CAS :Vidofludimus hemicalcium: oral DHODH inhibitor, FXR modulator, for autoimmune and fatty liver research.Formule :C20H18FNO4CaCouleur et forme :SolidMasse moléculaire :375.4AG-636
CAS :<p>AG-636 is a potent, reversible, selective and orally active DHODH inhibitor(IC50 of 17 nM). It has strong anticancer effects.</p>Formule :C21H17N3O2Degré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :343.38Sodium dichloroacetate
CAS :<p>Sodium dichloroacetate (BCA) inhibits PDK (IC50: 183 μM PDK2, 80 μM PDK4), triggers cancer cell apoptosis, and impedes tumor growth.</p>Formule :C2HCl2NaO2Degré de pureté :99.32% - 99.87%Couleur et forme :White PowderMasse moléculaire :150.92A939572
CAS :<p>A939572 is stearoyl-CoA desaturase1 (SCD1) inhibitor with IC50 values of <4 nM for mSCD1 and 37 nM for hSCD1.</p>Formule :C20H22ClN3O3Degré de pureté :99.96% - ≥95%Couleur et forme :SolidMasse moléculaire :387.86Proguanil hydrochloride
CAS :<p>Proguanil hydrochloride, a biguanide, metabolizes into cycloguanil, an anti-malaria agent that inhibits plasmodium's DNA and protein synthesis.</p>Formule :C11H17Cl2N5Degré de pureté :98.34% - 98.39%Couleur et forme :SolidMasse moléculaire :290.19Ivosidenib
CAS :<p>Ivosidenib (AG-120) is an oral IDH1 inhibitor targeting mutated IDH1 to reduce 2-hydroxyglutarate and hinder tumor growth.</p>Formule :C28H22ClF3N6O3Degré de pureté :98.71% - 99.98%Couleur et forme :SolidMasse moléculaire :582.96Tiazofurin
CAS :<p>Tiazofurin, a synthetic nucleoside, has anti-cancer effects and inhibits IMPDH as TAD after metabolism.</p>Formule :C9H12N2O5SDegré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :260.27Galloflavin
CAS :<p>Galloflavin is a lactate dehydrogenase inhibitor. Galloflavin inhibits both human LDH isoforms (type A and type B).Cost-effective and quality-assured.</p>Formule :C12H6O8Degré de pureté :96.24% - 97.47%Couleur et forme :SolidMasse moléculaire :278.17NCT-505
CAS :<p>NCT-505 is a potent and selective inhibitor of aldehyde dehydrogenase (ALDH1A1, IC50 = 7 nM) and a weak inhibitor of hALDH1A2, hALDH1A3, hALDH2, hALDH3A1 with</p>Formule :C27H28FN5O3SDegré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :521.61VER-246608
CAS :<p>VER-246608 inhibits PDK (IC50: 35-91 nM), boosts PDC, reduces glycolysis, causes cancer cell cytostasis, and enhances doxorubicin effects.</p>Formule :C28H23ClF2N4O4Degré de pureté :98.5%Couleur et forme :SolidMasse moléculaire :552.96Mutant IDH1-IN-1
CAS :<p>Mutant IDH1-IN-1 is a potent mutant IDH1 R132 h inhibitor with IC50 < 0.1 uM.</p>Formule :C30H31FN4O2Degré de pureté :99.49% - >99.99%Couleur et forme :SolidMasse moléculaire :498.59NCT-503
CAS :<p>NCT-503 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor with no activity against other dehydrogenases. NCT-503 has antitumor activity. Cost-effective and quality-assured.</p>Formule :C20H23F3N4SDegré de pureté :98.91% - 99.84%Couleur et forme :SolidMasse moléculaire :408.48L-Allylglycine
CAS :<p>L-Allylglycine is a potent inhibitor of the synthetic enzyme for GABA, glutamic acid decarboxylase.</p>Formule :C5H9NO2Degré de pureté :≥98%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :115.13CM10
CAS :<p>CM10 is an aldehyde dehydrogenase 1A family(ALDH1A) inhibitor.</p>Formule :C20H23N3ODegré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :321.42NCT-501
CAS :<p>NCT-501 is a potent and selective inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1) with IC50 of 40 nM.</p>Formule :C21H32N6O3Degré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :416.52AGI-5198
CAS :<p>AGI-5198 (IDH-C35) is a highly effective and specific inhibitor of IDH1 R132H/R132C mutants (IC50: 0.07/0.16 μM).</p>Formule :C27H31FN4O2Degré de pureté :97.37% - 99.23%Couleur et forme :SolidMasse moléculaire :462.56Nifurtimox
CAS :<p>Nifurtimox (BAY-A-2502) is an antiprotozoal agent (IC50s = 9.91, 12.28, and 10.44 μM against Taluahuén, LQ, and Brener strains of T.</p>Formule :C10H13N3O5SDegré de pureté :99.87% - 99.89%Couleur et forme :SolidMasse moléculaire :287.29BAY-1436032
CAS :<p>BAY-1436032 is a novel, selective and orally available inhibitor of pan-mutant isocitrate dehydrogenase 1 (IDH1).</p>Formule :C26H30F3N3O3Degré de pureté :99.65% - 99.71%Couleur et forme :SolidMasse moléculaire :489.53WIN 18446
CAS :<p>inhibitor of aldehyde dehydrogenase 1a2 (ALDH1a2)</p>Formule :C12H20Cl4N2O2Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :366.11Brequinar sodium
CAS :<p>Bipenquinate is a potent and selective inhibitor of dihydroorotate dehydrogenase (DHODH) with IC50 of 20 nM, blocking de novo pyrimidine biosynthesis.</p>Formule :C23H14F2NNaO2Degré de pureté :98.16%Couleur et forme :SolidMasse moléculaire :397.36Fomepizole
CAS :<p>Fomepizole (4-Methylpyrazole), a competitive inhibitor of alcohol dehydrogenase, is used as an antidote in methanol or ethylene glycol poisoning.</p>Formule :C4H6N2Degré de pureté :98.1% - 99.94%Couleur et forme :Yellow <13°C Solid >13°C LiquidMasse moléculaire :82.1Imidazole-5-propionic acid
CAS :<p>Imidazole-5-propionic acid (Imidazolylpropionic acid) is a product of histidine metabolism and may involve oxidation or transamination.</p>Formule :C6H8N2O2Degré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :140.14AG-120 (racemic)
CAS :<p>AG-120 (racemic) is an oral IDH1 inhibitor with potential anti-cancer effects.</p>Formule :C28H22ClF3N6O3Degré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :582.96Vidofludimus
CAS :<p>Vidofludimus (SC12267) (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH).</p>Formule :C20H18FNO4Degré de pureté :98.33% - 99.58%Couleur et forme :SolidMasse moléculaire :355.36BVT-14225
CAS :<p>BVT-14225 is a selective 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor (IC50=52 nM).</p>Formule :C16H20ClN3O3S2Degré de pureté :97.78%Couleur et forme :SolidMasse moléculaire :401.93(R)-GNE-140
CAS :<p>(R)-GNE-140 (GNE-140) is an effective LDHA/LDHB inhibitor (IC50s: 3/5 nM) and is 18-fold more potent than S enantiomer.</p>Formule :C25H23ClN2O3S2Degré de pureté :98.25% - 98.91%Couleur et forme :SolidMasse moléculaire :499.04Succinyl phosphonate trisodium salt
CAS :<p>Succinyl phosphonate trisodium salt is an inhibitor of α-ketoglutarate dehydrogenase (KGDHC)</p>Formule :C4H4Na3O6PDegré de pureté :99.8% - ≥95%Couleur et forme :SolidMasse moléculaire :248.01SW033291
CAS :<p>SW033291 is a small-molecule inhibitor of 15-PGDH (Ki=0.1 nM) that increases prostaglandin PGE2 levels in bone marrow and other tissues.</p>Formule :C21H20N2OS3Degré de pureté :97.26% - 99.02%Couleur et forme :SolidMasse moléculaire :412.593-Hydroxybenzaldehyde
CAS :<p>3-Hydroxybenzaldehyde is a compound useful in organic synthesis.</p>Formule :C7H6O2Degré de pureté :99.60%Couleur et forme :DrypowderMasse moléculaire :122.126PGD-IN-S3
CAS :<p>6PGD-IN-S3 (6PGD Inhibitor S3) is an inhibitor of 6-phosphogluconate dehydrogenase (6PGD).</p>Formule :C15H10O4Degré de pureté :99.12%Couleur et forme :SolidMasse moléculaire :254.24Enasidenib
CAS :<p>Enasidenib (AG-221) is an orally available inhibitor of specific mutant forms of the mitochondrial enzyme isocitrate dehydrogenase type 2 (IDH2), with potential</p>Formule :C19H17F6N7ODegré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :473.38Enasidenib mesylate
CAS :<p>Enasidenib mesylate (AG-221 mesylate) is a IDH2 inhibitor that promotes differentiation of leukemia myeloid cells for the treatment of acute myeloid leukemia.</p>Formule :C20H21F6N7O4SDegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :569.48DS44960156
CAS :<p>DS44960156 is an inhibitor of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) that inhibits both MTHFD2 and MTHFD1 and can be used in cancer research.</p>Formule :C20H15NO5Degré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :349.34GSK1940029
CAS :<p>GSK1940029 (SCD inhibitor 1) is a stearoyl-coa desaturase (SCD) inhibitor.</p>Formule :C18H16Cl2N4O2Degré de pureté :99.48% - 99.49%Couleur et forme :SolidMasse moléculaire :391.25Triflupromazine
CAS :<p>Triflupromazine is a dopamine receptor D1/D2 antagonist and LHDA inhibitor that suppresses dopamine activity in (CNS)mental disorders, sedation, and antiemesis.</p>Formule :C18H19F3N2SCouleur et forme :SolidMasse moléculaire :352.42hDHODH-IN-2
CAS :<p>hDHODH-IN-2: Leflunomide metabolite analog, inhibits human dihydroorotate dehydrogenase, anti-inflammatory.</p>Formule :C19H16N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :304.349Nitrophenide
CAS :<p>Nitrophenide, a 3,3'-Dinitrodiphenyl disulfide, blocks M1PDH in the mannitol cycle, serving as an anticoccidial.</p>Formule :C12H8N2O4S2Degré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :308.33AGI-14100
CAS :<p>AGI-14100 is a novel and orally available mIDH1 inhibitor.AGI-14100 is used for the treatment of primary human myeloid leukemia.</p>Formule :C29H22ClF4N5O3Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :599.96Epostane
CAS :<p>Epostane is a 3β-hydroxysteroid dehydrogenase inhibitor that blocks the biosynthesis of progesterone and pregnenolone.Cost-effective and quality-assured.</p>Formule :C22H31NO3Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :357.49DHODH-IN-24
CAS :<p>DHODH-IN-24 (compound 16) serves as a powerful inhibitor of human dihydroorotate dehydrogenase (DHODH), exhibiting an IC50 value of 91 nM [1].</p>Formule :C26H26N4Couleur et forme :SolidMasse moléculaire :394.51IMB-XMA0038
CAS :<p>IMB-XMA0038 is a Mycobacterium tuberculosis aspartate semialdehyde dehydrogenase inhibitor with antimicrobial activity for use in tuberculosis research.</p>Formule :C11H10N4O6Degré de pureté :98.94% - 99.96%Couleur et forme :SolidMasse moléculaire :294.22BI-4924
CAS :<p>BI-4924 is a PHGDH inhibitor that disrupts serine biosynthesis by intracellular trapping and can be used to study metabolic disorders.</p>Formule :C21H20Cl2N2O6SDegré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :499.36NCT-506
CAS :<p>NCT-506 is an orally bioavailable inhibitors of aldehyde dehydrogenase 1A1 (ALDH1A1) (IC50 of 7 nM).</p>Formule :C25H23FN4O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :478.54SCH-451659
CAS :<p>SCH-451659 is an 17β-hydroxysteroid dehydrogenases (17β-HSDs) inhibitor.</p>Formule :C30H39Cl2N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :544.56BI-135585
CAS :<p>BI-135585 is an orally active, selective and potent inhibitor of human 11β-hydroxysteroid dehydrogenase-1 (HSD1) for the study of type 2 diabetes.</p>Formule :C28H32N2O4Degré de pureté :99.45% - 99.57%Couleur et forme :SolidMasse moléculaire :460.57CM026
CAS :<p>CM026 inhibits ALDH1A1 selectively, binds to its aldehyde pocket uncompetitively.</p>Formule :C22H30N6O4Couleur et forme :SolidMasse moléculaire :442.51ML387
CAS :<p>ML387 is an inhibitor of human NAD(+)- dependent 15- hydroxyprostaglandin dehydrogenase.</p>Formule :C20H21N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :335.4
