Déshydrogénase
Les déshydrogénases sont des enzymes impliquées dans les réactions d'oxydoréduction des voies métaboliques, jouant un rôle central dans la production d'énergie et la respiration cellulaire. Ces enzymes sont cruciales pour des processus tels que le cycle de l'acide citrique, la glycolyse et l'oxydation des acides gras. Les inhibiteurs de déshydrogénases sont des outils importants dans l'étude des maladies métaboliques, du cancer et du stress oxydatif. Chez CymitQuimica, nous proposons une sélection complète d'inhibiteurs de déshydrogénases pour soutenir vos recherches en métabolisme, biologie du cancer et biochimie.
267 produits trouvés pour "Déshydrogénase"
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Oxycinchophen
CAS :<p>Oxycinchophen: Quinoline-based anti-rheumatic with P-selectin inhibition, DHOD blockade, and anti-inflammatory impacts on vascular muscle.</p>Formule :C16H11NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :265.26GW648495
CAS :<p>GW648495 is a PfDHODH inhibitor that shows greater than 4,000-fold selectivity for the malarial enzyme.</p>Formule :C16H13N5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :275.31BVT-116429
CAS :<p>BVT-116429 is an inhibitor of 11β-HSD1.</p>Formule :C13H12F4N2OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :320.31GA11
CAS :<p>GA11is an inhibitor of ALDH1. It also displays anti-GBM effects in vitro and in vivo.</p>Formule :C19H14N2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :270.33RS6212
CAS :<p>RS6212 is a specific lactate dehydrogenase (LDH) inhibitor (IC50=12.03 μ M）。 RS6212 shows strong anticancer activity in a variety of cancer cell lines.</p>Formule :C20H22N4O3SCouleur et forme :SolidMasse moléculaire :398.48RORγt/DHODH-IN-2
CAS :<p>RORγt/DHODH-IN-2 (compound 1) is a potent dual RORγt/DHODH inhibitor that can be used in the study of inflammatory bowel disease (IBD).</p>Formule :C25H30N4OSCouleur et forme :SolidMasse moléculaire :434.6UCK2 Inhibitor-2
CAS :<p>UCK2 Inhibitor-2 is a non-competitive inhibitor of uridine-cytidine kinase 2 (UCK2) with IC50=3.8 µM that inhibits UCK2-mediated nucleoside recycling in cells.</p>Formule :C28H23N3O4SDegré de pureté :98.76% - 99.25%Couleur et forme :SolidMasse moléculaire :497.57DHODH-IN-20
CAS :<p>Dhodh-in-20 (Compound 133), a potent DHODH inhibitor, may help study acute myeloid leukemia and inhibit tumor growth.</p>Formule :C24H25F4N3O3Couleur et forme :SolidMasse moléculaire :479.47hDHODH-IN-4
CAS :<p>hDHODH-IN-4, a potent DHODH inhibitor, has a pIC50 of 7.8 and blocks measles virus replication with a pMIC50 of 8.8.</p>Formule :C21H24N4O2Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :364.44ALDH1A1-IN-3
CAS :<p>ALDH1A1-IN-3 selectively inhibits ALDH1A1, enhances HepG2 glucose consumption for metabolic research.</p>Formule :C31H36F3N5O4Couleur et forme :SolidMasse moléculaire :599.64AZD8329
CAS :<p>AZD8329 is an 11β-HSD1 inhibitor that inhibits 11β-HSD2, 17β-HSD1, 17β-HSD3, and can be used to study allergic reactions in humans.</p>Formule :C25H31N3O3Degré de pureté :99.31%Couleur et forme :SolidMasse moléculaire :421.53KM04416
CAS :<p>KM04416 is a GPD2 inhibitor that inhibits LUAD progression by modulating immune cell infiltration.</p>Formule :C12H11NO3SDegré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :249.29ALDH1A1-IN-2
CAS :<p>ALDH1A1-IN-2 is an aldehyde dehydrogenase 1a1 inhibitor with anticancer activity.ALDH1A1-IN-2 may be used in the study of breast cancer, inflammation or obesity</p>Formule :C25H23ClN4O3SDegré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :494.99Laflunimus
CAS :<p>Laflunimus (HR325) is a DHODH inhibitor that inhibits immunoglobulin secretion in vitro and in vivo,by interfering with pyrimidine metabolism,neuralgia.</p>Formule :C15H13F3N2O2Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :310.27hDHODH-IN-9
CAS :<p>hDHODH-IN-9 is a potent hDHODH inhibitor, IC50=0.34 μM, toxic to MCF-7/A375 cells, promising for cancer research.</p>Formule :C21H21NO4Couleur et forme :SolidMasse moléculaire :351.4RV01
CAS :<p>RV01, a resveratrol-like quinoline, inhibits DNA damage, ALDH2 expression, and has antioxidant and anti-inflammatory properties.</p>Formule :C17H13NO2Degré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :263.29hDHODH-IN-3
CAS :<p>hDHODH-IN-3 is an inhibitor of human dihydroorotate dehydrogenase with a pMIC50 value of 8.6. hDHODH-IN-3 can inhibit measles virus replication.</p>Formule :C18H19BrN4O2Degré de pureté :99.871%Couleur et forme :SolidMasse moléculaire :403.27Genz-669178
CAS :<p>Genz-669178 is a wild-type inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH).</p>Formule :C17H14N4OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :322.38EN40
CAS :<p>EN40, as a covalent ligand, is a selective inhibitor of aldehyde dehydrogenase 3A1 (IC50: 2 uM).</p>Formule :C13H15NO2Couleur et forme :SolidMasse moléculaire :217.26DHODH-IN-13
CAS :<p>DHODH-IN-13 is an inhibitor of DHODH with IC50 of 4.3 μM for rat liver. DHODH-IN-13 can be used in studies about rheumatoid arthritis.</p>Formule :C10H6F3N3O3Degré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :273.17DHODH-IN-15
CAS :<p>DHODH-IN-15, a hydroxyfuran analogue of A771726, inhibits rat liver DHODH with an IC50 of 11 μM, and is used for rheumatoid arthritis.</p>Formule :C15H11N3O3Degré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :281.27DHODH-IN-17
CAS :<p>DHODH-IN-17 is a human DHODH inhibitor with an IC50 of 0.40 μM.</p>Formule :C12H9ClN2O2Degré de pureté :99.41% - 99.52%Couleur et forme :SolidMasse moléculaire :248.67DHODH-IN-1
CAS :<p>DHODH-IN-1 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 25 nM. DHODH-IN-1 is an inhibitor of the pyrimidine biosynthetic pathway.</p>Formule :C21H20F3N3O2Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :403.4hDHODH-IN-5
CAS :<p>hDHODH-IN-5 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH, IC50 = 0.91 μM).</p>Formule :C21H21F3N2O2Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :390.4p-Valerylphenol
CAS :<p>p-Valerylphenol (NSC-49186) can be used to synthesize acylphenoxyacetic acid compounds.</p>Formule :C11H14O2Degré de pureté :99.87%Couleur et forme :White To Light Beige PowderMasse moléculaire :178.23M77976
CAS :<p>M77976 inhibits PDK4 with an IC50 of 648 μM, targeting obesity and diabetes research.</p>Formule :C17H16N2O3Degré de pureté :99.43%Couleur et forme :SolidMasse moléculaire :296.32Manitimus
CAS :<p>Manitimus is a potent immunosuppressive drug, and is an inhibitor of dehydroorotate dehydrogenase,.</p>Formule :C15H11F3N2O2Degré de pureté :99.75% - 99.75%Couleur et forme :SolidMasse moléculaire :308.26Metapramine
CAS :<p>Metapramine, a tricyclic antidepressant, blocks norepinephrine reuptake and is a low-affinity NMDA antagonist.</p>Formule :C16H18N2Degré de pureté :99.03% - 99.67%Couleur et forme :SolidMasse moléculaire :238.3311β-HSD1-IN-1
CAS :<p>11β-HSD1-IN-1 is an inhibitor of 11β-hydroxydehydrogenase 1 (11β-HSD1, IC50: 52 nM), and used for the treatment of pain.</p>Formule :C18H14ClF4N3ODegré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :399.77DHODH-IN-4
CAS :<p>DHODH-IN-4 inhibits human & Plasmodium DHODH; IC50: 4 μM (Pf), 0.18 μM (Hs). It has antimalarial properties.</p>Formule :C17H12Cl2N2O2Degré de pureté :99.34%Couleur et forme :SolidMasse moléculaire :347.2DHODH-IN-8
CAS :<p>DHODH-IN-8 is a DHODH inhibitor with antimalarial properties, IC50: 0.13 μM (human), 47.4 μM (P. falciparum); Ki: 0.016 μM (human), 5.6 μM (P. falciparum).</p>Formule :C17H13ClN2O2Degré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :312.7511β-HSD1-IN-12
CAS :<p>11β-HSD1-IN-12 is an 11β-HSD1 inhibitor.11β-HSD1-IN-12 is implicated in the conversion of glucocorticoids in vivo and can be used to study metabolic syndrome</p>Formule :C19H27ClN2O3SDegré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :398.95Nitrefazole
CAS :<p>Nitrefazole: a 4-nitroimidazole, inhibits ALDH enzyme crucial for alcohol metabolism, has potent, durable effects.</p>Formule :C10H8N4O4Couleur et forme :SolidMasse moléculaire :248.1911β-HSD1-IN-6
CAS :<p>11β-HSD1-IN-6 is a potent inhibitor of 11β hydroxysteroid dehydrogenase enzymes (11β-HSDs).</p>Formule :C21H19ClN4OCouleur et forme :SolidMasse moléculaire :378.86CM39
CAS :<p>CM39 inhibits ALDH, linked to cancer stem-like cells & chemoresistance.</p>Formule :C19H15FN4OSCouleur et forme :SolidMasse moléculaire :366.41MEDS433
CAS :<p>MEDS433 inhibits dihydroorotate dehydrogenase (IC50 1.2 nM) and blocks replication of hCoV-OC43, hCoV-229E, SARS-CoV-2 at nanomolar levels.</p>Formule :C20H11F4N3O2Couleur et forme :SolidMasse moléculaire :401.31hDHODH-IN-11
CAS :<p>hDHODH-IN-11: potent hDHODH inhibitor, IC50 7.2 nM, low cytotoxicity, for AML research.</p>Formule :C24H23N3O3Couleur et forme :SolidMasse moléculaire :401.46DHODH-IN-12
CAS :<p>DHODH-IN-12 is a leflunomide derivative and a weak dihydrorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.07.</p>Formule :C10H9N3O2Degré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :203.2AMG-221
CAS :<p>AMG-221: potent 11β-HSD1 inhibitor, lowers glucose & insulin, reduces obesity in mice.</p>Formule :C14H22N2OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :266.411β-HSD1-IN-10
CAS :<p>11β-HSD1-IN-10, a potent inhibitor of 11β-HSD1 with an IC50 value of 1.8 µM for humans, is suitable for research into obesity, hyperglycemia, and cognitive</p>Formule :C16H10F3NO2Couleur et forme :SolidMasse moléculaire :305.25673-A
CAS :<p>673-A inhibits ALDH1A, depletes ovarian CSCs, induces necroptosis, and reverses chemo resistance.</p>Formule :C15H13NOCouleur et forme :SolidMasse moléculaire :223.27DHODH-IN-19
CAS :<p>DHODH-IN-19, a strong DHODH blocker, may help treat cancer and inflammation. (Patent WO2021238881A1)</p>Formule :C22H18ClF6N3O3Couleur et forme :SolidMasse moléculaire :521.84ASP3662
CAS :<p>ASP3662/SPI-62: Potent, selective CNS-penetrable 11β-HSD1 inhibitor; potential neuropathic pain treatment.</p>Formule :C19H16ClF3N4O2Couleur et forme :SolidMasse moléculaire :424.8TM-1
CAS :<p>TM-1: PDHK inhibitor, IC50 - PDHK1: 2.97μM, PDHK2: 5.2μM, prevents PDHC phosphorylation, inhibits cancer cell growth.</p>Formule :C26H32N2O6Couleur et forme :SolidMasse moléculaire :468.54DHODH-IN-3
CAS :<p>DHODH-IN-3: Human DHODH inhibitor with IC50 of 261 nM, Kiapp 32 nM, potential anti-malaria drug.</p>Formule :C17H13ClN2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :312.75ALDH3A1-IN-2
CAS :<p>ALDH3A1-IN-2 is a potent inhibitor targeting ALDH3A1 (IC50=1.29µM), potentially useful in cancer research.</p>Formule :C11H14N2O3Couleur et forme :SolidMasse moléculaire :222.2411β-HSD1-IN-9
CAS :<p>11β-HSD1-IN-9 is a potent inhibitor of 11β-HSD1, displaying IC50 values of 0.48 µM for human and 1.3 µM for murine variants, respectively.</p>Formule :C13H9F3N2OCouleur et forme :SolidMasse moléculaire :266.22DHODH-IN-21
CAS :<p>DHODH-IN-21, orally active DHODH blocker with 1.1 nM IC50, shows anticancer activity, potential for AML research.</p>Formule :C20H19ClF4N6O4Couleur et forme :SolidMasse moléculaire :518.85BRD9185
CAS :<p>BRD9185 is an inhibitor of Dihydroorotate dehydrogenase (DHODH) with an EC50 of 16 nM against multidrug-resistant blood-stage parasites in vitro.</p>Formule :C23H21F6N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :485.42P1788
CAS :<p>P1788 is a dihydroorotate dehydrogenase (DHODH) inhibitor that can induce DNA damage [1].</p>Formule :C15H17NO3Couleur et forme :SolidMasse moléculaire :259.3
