Microbiologie/Virologie
Les inhibiteurs en microbiologie et virologie sont des composés qui ciblent les microorganismes, y compris les bactéries, les virus et les champignons, perturbant leur croissance, leur réplication ou leur survie. Ces inhibiteurs sont essentiels pour étudier la pathogénie microbienne, comprendre les mécanismes de résistance et développer de nouvelles thérapies antimicrobiennes et antivirales. Les inhibiteurs de cette catégorie sont utilisés pour combattre les maladies infectieuses, explorer l'écologie microbienne et étudier les interactions hôte-pathogène. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de haute qualité en microbiologie et virologie pour soutenir vos recherches en maladies infectieuses, microbiologie et virologie.
Sous-catégories appartenant à la catégorie "Microbiologie/Virologie"
- Antibactérien(2.949 produits)
- Antibiotique(918 produits)
- Antifection(23 produits)
- DHFR(32 produits)
- Synthèse ADN/ARN(706 produits)
- VHB(176 produits)
- Protéase du VIH(447 produits)
- HSV(91 produits)
- Intégrase(2 produits)
- Ribosome(13 produits)
Affichez 2 plus de sous-catégories
5832 produits trouvés pour "Microbiologie/Virologie"
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N-Nitrosonornicotine
CAS :<p>N-Nitrosonornicotine, a tobacco-specific nitrosamine, exhibits carcinogenic and mutagenic properties, and is capable of inducing micronuclei in C3A cells. Additionally, N-Nitrosonornicotine can form DNA adducts.</p>Formule :C9H11N3OCouleur et forme :SolidMasse moléculaire :177.2TAN-1057C
CAS :<p>TAN-1057C is a potent antibiotic with antimicrobial activity against both Gram-negative and Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA).</p>Formule :C13H25N9O3Couleur et forme :SolidMasse moléculaire :355.4HBV-IN-20
<p>HBV-IN-20 is a potent, orally active HBV inhibitor (EC50: 0.46 μM). HBV-IN-20 is a classical type II CpAM (core protein assembly regulator).</p>Couleur et forme :SolidPfCLK3-IN-1
<p>PfCLK3-IN-1 (Compound 4) serves as a covalent inhibitor of the malaria parasite CLK3 (Pf CLK3) under alkaline conditions, with a pEC50 of 7.1. It inhibits the maturation of gametocytes during the sexual stage of the parasite, thereby hindering transmission. Additionally, PfCLK3-IN-1 effectively suppresses the Dd2-B2 clone of the malaria parasite, exhibiting an IC50 of 239.5 nM.</p>Formule :C28H27ClN4O4Couleur et forme :SolidMasse moléculaire :518.99Antimalarial agent 44
<p>Antimalarial agent 44 (Compound 3) is an antiparasitic agent effective against malaria. It exhibits good permeability in MDCK-MDR1 cell monolayers and has a high clearance rate in mouse liver microsomes.</p>Formule :C37H37N5O7Couleur et forme :SolidMasse moléculaire :663.72MTI013
<p>MTI013 is a selective inhibitor of SARS-CoV-2 nsp14 Mtase (IC50: 2.98 µM) and an antiviral agent (IC50: 10.33 µM in HCoV-229E infected Huh7 cells). Additionally, MTI013 demonstrates synergistic antiviral effects when used in conjunction with the RdRp inhibitor SHEN26.</p>Formule :C24H26N6O4SCouleur et forme :SolidMasse moléculaire :494.57MLEB-22043
<p>MLEB-22043 is a synthetic siderophore-monocyclic β-lactam conjugate which enters bacteria through TonB-dependent transport proteins utilizing its siderophore component, subsequently exerting antibacterial activity via its β-lactam portion. This compound acts as a broad-spectrum antibiotic, exhibiting significant inhibitory activity against pathogens such as Klebsiella pneumoniae, Escherichia coli, Acinetobacter baumannii, and Pseudomonas aeruginosa.</p>Formule :C25H25N9O11S2Couleur et forme :SolidMasse moléculaire :691.65Ac-Atovaquone
CAS :<p>Ac-Atovaquone, an ester-acetylated derivative of atovaquone, acts as a potent inhibitor of cytochrome bc1 (cytochrome bc1). This compound shows potential for use in malaria research.</p>Formule :C24H21ClO4Couleur et forme :SolidMasse moléculaire :408.87QPX7728 methoxy acetoxy methy ester
CAS :<p>QPX7728 methoxy acetoxy methy ester is an inhibitor of boronic acid β-lactamase.</p>Formule :C14H14BFO7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :324.072,5-Di-tert-butyl-1,4-benzoquinone
CAS :<p>2,5-Di-tert-butyl-1,4-benzoquinone is a potent antibacterial agent found primarily in marine Streptomyces sp. VITVSK1, effective against emerging antibiotic resistance. Additionally, it serves as a powerful inhibitor of RNA polymerase.</p>Formule :C14H20O2Couleur et forme :SolidMasse moléculaire :220.31SARS-CoV-2 Mpro-IN-34
<p>SARS-CoV-2 Mpro-IN-34 (Compound 26) acts as an inhibitor of SARS-CoV-2 Mpro with an IC50 of 6 nM. It also inhibits OC43 Mpro, demonstrating an IC50 of 33 nM. Furthermore, this compound exhibits antiviral activity in Vero E6 cells infected with SARS-CoV-2, with an EC50 of 0.103 μM.</p>Formule :C30H37Cl2N5O3Couleur et forme :SolidMasse moléculaire :586.55Cefamandole lithium
CAS :<p>Cefamandole (lithium), a second-generation broad-spectrum cephalosporin antibiotic, exhibits antimicrobial activity. Upon metabolism in the body, it releases free NMTT, which can lead to hypoprothrombinemia.</p>Formule :C18H17LiN6O5S2Couleur et forme :SolidMasse moléculaire :468.44Cilastatin ammonium salt
CAS :<p>Cilastatin ammonium salt is an antibiotic that is particularly effective against Gram-positive cocci, with a half-life of 3-4 hours.</p>Formule :C16H29N3O5SCouleur et forme :SolidMasse moléculaire :375.48Ganaplacide hydrochloride
CAS :<p>Ganaplacide hydrochloride (KAF156 HCl) is an orally administered imidazopyrimidine antimalarial agent that inhibits Plasmodium PI4K activity.</p>Formule :C22H24ClF2N5ODegré de pureté :93.97%Couleur et forme :SoildMasse moléculaire :447.91AV-5080
CAS :<p>AV-5080 is an orally active neuraminidase (neuraminidase) inhibitor that is utilized in the research of both Type A and Type B influenza viruses.</p>Formule :C15H25FN4O4Couleur et forme :SolidMasse moléculaire :344.38Anti-MRSA agent 19
CAS :<p>Anti-MRSA agent 19 (Compound 1) is an antibiotic that exhibits activity against Staphylococcus aureus. It is active against 40 clinical isolates from the CDC, representing diverse bacterial species with various resistance factors, including resistance to vancomycin, aminoglycoside/tetracycline, and oxazolidinone (median MIC=4 μg/mL).</p>Formule :C15H10Cl3NO4Couleur et forme :SolidMasse moléculaire :374.6Isazofos
CAS :<p>Isazofos is a broad-spectrum organophosphate insecticide and nematicide effective in controlling a variety of lawn pests, such as nematodes (Radopholus similis). It also demonstrates efficacy in managing rice gall midge.</p>Formule :C9H17ClN3O3PSCouleur et forme :SolidMasse moléculaire :313.74Finafloxacin
CAS :<p>Finafloxacin is a pH-activated fluoroquinolone, most effective at pH 5.0-6.0, targeting bacterial topoisomerases, used for UTIs and H. pylori infections.</p>Formule :C20H19FN4O4Couleur et forme :SolidMasse moléculaire :398.39Antifungal agent 11
<p>Antifungal agent 11 has a good antifungal effect.</p>Formule :C21H19F2N7O3S2Couleur et forme :SolidMasse moléculaire :519.55MTH1 activator-1
CAS :<p>MTH1 activator-1 is an MTH1 activator that enhances endogenous MTH1 activity and significantly reduces 8-oxo-dG levels in cellular DNA. It is useful for investigating the upregulation of oxidative damage repair in nucleotide pools and examining biological effects, as well as for studies aiming to delay or prevent tumorigenesis.</p>Formule :C29H23F3N4O2Couleur et forme :SolidMasse moléculaire :516.514MI-1851
CAS :<p>MI-1851 is a potent peptidomimetic inhibitor. MI-1851could prevent proteolytic processing of the S protein from SARSCoV-2 by endogenous furin in HEK293 cells.</p>Formule :C34H53N15O6Couleur et forme :SolidMasse moléculaire :767.88Antibacterial agent 82
<p>Antibacterial agent 82 (compound 7p) is an antibacterial agent [1].</p>Formule :C22H18N2O2Couleur et forme :SolidMasse moléculaire :342.39G247
<p>G247 inhibits MsbA by keeping NBDs apart, blocking ATPase activity.</p>Formule :C24H19Cl2FO3Couleur et forme :SolidMasse moléculaire :445.31KPC-2-IN-2
<p>KPC-2-IN-2 (6c) inhibits KPC-2 enzyme in Klebsiella pneumoniae (Ki 0.038 μM) and boosts cefotaxime in E. coli KPC-2.</p>Formule :C12H10BN3O2SCouleur et forme :SolidMasse moléculaire :271.1GS-9822
CAS :<p>GS-9822 is a new LEDGIN inhibitor targeting LEDGF/p75 to alter HIV integration, showing a block-and-lock effect in cells.</p>Formule :C36H39ClN4O4SCouleur et forme :SolidMasse moléculaire :659.24PKZ18
CAS :<p>PKZ18 is an antibiotic that inhibits bacterial growth with a MIC value of 32-64 μg/mL against most Gram-positive bacteria. It suppresses the in vivo transcription and translation of glycyl-tRNA synthetase mRNA. PKZ18 selectively targets stem I specifier loops in Gram-positive bacteria, directly reducing T-box transcription readthrough of associated genes. It prevents codon-anticodon pairing necessary for tRNA binding and is less likely to induce resistance.</p>Formule :C22H26N2O3SCouleur et forme :SolidMasse moléculaire :398.5183HKT-IN-1
CAS :<p>3HKT-IN-1 (Compound 17122279) is an inhibitor of Anopheles gambiae 3-hydroxykynurenine transaminase (3HKT) and is utilized in malaria research.</p>Formule :C12H11BrN2O3Couleur et forme :SolidMasse moléculaire :311.131MsbA-IN-3
<p>MsbA-IN-3 is a potent and highly selective MsbA inhibitor (IC50: 2 nM). MsbA-IN-3 inhibits Escherichia coli activity (MIC: 35 μM).</p>Formule :C24H22Cl2N2O4SCouleur et forme :SolidMasse moléculaire :505.41Tuberculosis inhibitor 4
<p>TB inhibitor 4, a spirothiazolidinone from mandelic acid, blocks 98% of M. tuberculosis H37Rv under 6 μg/mL.</p>Formule :C23H26N2O3SCouleur et forme :SolidMasse moléculaire :410.533-Deazaguanosine
CAS :<p>3-Deazaguanosine (C3Guo) exhibits potent antiviral activity against SARS-CoV-2 with an EC50 of 1.14 μM and a CC50 greater than 200 μM in Vero E6 cells. It has the potential to prevent COVID-19.</p>Formule :C11H14N4O5Couleur et forme :SolidMasse moléculaire :282.25Furametpyr
CAS :<p>Furametpyr is a kind of low toxicity pesticides used to control plant diseases caused by various pathogenic microorganisms.</p>Formule :C17H20ClN3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :333.81Antibacterial agent 63
CAS :<p>Aztreonam-siderophore conjugate 63 is an antibacterial agent that exhibits efficacy against Gram-negative bacteria through the linkage of aztreonam to a</p>Formule :C35H43N9O14S2Couleur et forme :SolidMasse moléculaire :877.9ZK-806450
CAS :<p>ZK-806450 is a compound with antiviral properties. It exhibits high binding potential to the allosteric site of the SARS-CoV-2 3CL protease and is capable of specific and stable interaction with the GAG site of the dengue virus envelope protein.</p>Formule :C31H31N5OCouleur et forme :SolidMasse moléculaire :489.611Cyclophilin inhibitor 1
CAS :<p>Cyclophilin inhibitor 1: orally available, Kd 5 nM, potent against HCV, EC50 for HCV 2a is 98 nM.</p>Formule :C31H39N5O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :593.67PLP_Snyder530
<p>PLP_Snyder530, a potent PL pro inhibitor, halts SARS-CoV-2 by triggering protease conformation changes.</p>Formule :C24H24N2O2Couleur et forme :SolidMasse moléculaire :372.46Antibacterial agent 90
<p>Antibacterial agent 90 (6n), a pleuromutilin derivative, targets Gram-positive pathogens and Mycoplasma pneumoniae.</p>Formule :C30H42N2O6Couleur et forme :SolidMasse moléculaire :526.66Squalamine lactate
CAS :<p>Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity.</p>Formule :C37H71N3O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :718.04Anti-MRSA agent 6
<p>Anti-MRSA agent 6 (compound 3q6) is a potent anti-methicillin-resistant Staphylococcus aureus (anti-MRSA) agent with low cytoxicity for MCF-7, A549 cells [1].</p>Formule :C16H11F2N3Couleur et forme :SolidMasse moléculaire :283.28trans-Clopenthixol
CAS :<p>Trans-Clopenthixol ((E)-Clopenthixol) is an antibiotic without any sedative properties. It can be used in vitro to inhibit Pseudomonas aeruginosa and Plasmodium falciparum.</p>Formule :C22H25ClN2OSCouleur et forme :SolidMasse moléculaire :400.965Saphenamycin
CAS :<p>Saphenamycin is an antibiotic from a strain of Streptomyces.</p>Formule :C23H18N2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :402.40RSV-IN-5
CAS :<p>RSV-IN-5: Dual inhibitor for RSV fusion proteins, effective on wild-type A2 and D486N mutant with EC50s of 2.0 nM & 8.1 nM. Potent anti-RSV.</p>Formule :C28H37N7O2Couleur et forme :SolidMasse moléculaire :503.64LolCDE-IN-2
CAS :<p>LolCDE-IN-2 is a potent Lol protein (LolCDE) inhibitor. LolCDE-IN-2 shows antibacterial activity with a MIC of 2 μg/ml against E. coli MG1655 [1].</p>Formule :C22H17N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :367.40Anti-MRSA agent 27
CAS :<p>Anti-MRSA agent 27 (compound 4a) is a potent antimicrobial agent against methicillin-resistant Staphylococcus aureus (MRSA) with a minimum inhibitory concentration (MIC) of 0.0975 μmol/L. It effectively disrupts MRSA biofilms and inhibits the production of hemolysins.</p>Formule :C15H10F3N3OSCouleur et forme :SolidMasse moléculaire :337.32A25822B
CAS :<p>A25822B is an antifungal agent.</p>Formule :C28H45NODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :411.66β-Glucuronidase-IN-2
<p>β-Glucuronidase-IN-2 is a potent inhibitor of E.</p>Formule :C21H17Cl3O7Couleur et forme :SolidMasse moléculaire :487.71Anti-infective agent 10
CAS :<p>Anti-infective agent 10 (Compound Example 30) is an ns5b polymerase inhibitor that functions as an anti-HCV agent.</p>Formule :C26H25N3O7SCouleur et forme :SolidMasse moléculaire :523.56Antibacterial agent 66
<p>Compound 6q, a trifluoromethylpyridine oxadiazole, targets Xanthomonas oryzae with EC50 of 7.2 μg/mL.</p>Formule :C17H10ClF6N3O2SCouleur et forme :SolidMasse moléculaire :469.79Valopicitabine
CAS :<p>Valopicitabine is an effective prodrug of the effective anti-HCV drug 2'-C-methylcytidine and can be used as a promising antiviral drug for the study of chronic</p>Formule :C15H24N4O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :356.37(Rac)-Plevitrexed
CAS :<p>(Rac)-Plevitrexed is a racemate of Plevitrexed. Plevitrexed is an orally active and potent inhibitor of thymidylate synthase (TS).</p>Formule :C26H25FN8O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :532.53PFK-IN-1
CAS :<p>PFK-IN-1 (compound 1) is an inhibitor of 6-phosphofructo-1-kinase (PFK), demonstrating IC50 values of 0.41 and 0.23 μM against T. brucei and T. cruzi PFK, respectively, and an ED50 of 15.18 μg/mL for T. brucei. The compound has a half-life of 9.7 minutes in rat liver microsomes and 408 minutes in mouse liver microsomes.</p>Formule :C18H15Cl2N3O4SCouleur et forme :SolidMasse moléculaire :440.3
