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Neuroscience

Neuroscience

Les inhibiteurs en neurosciences sont des composés conçus pour moduler l'activité de protéines, d'enzymes ou de récepteurs spécifiques au sein du système nerveux. Ces inhibiteurs sont cruciaux pour étudier les mécanismes moléculaires sous-jacents au fonctionnement neuronal, à la transmission synaptique et aux maladies neurodégénératives. En ciblant les récepteurs des neurotransmetteurs, les canaux ioniques et les voies de signalisation, les inhibiteurs en neurosciences facilitent l'exploration du fonctionnement cérébral et le développement de stratégies thérapeutiques pour des troubles neurologiques tels que la maladie d'Alzheimer, de Parkinson et l'épilepsie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs en neurosciences de haute qualité pour soutenir vos recherches en neurobiologie, neuropharmacologie et sciences cognitives.

Sous-catégories appartenant à la catégorie "Neuroscience"

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5397 produits trouvés pour "Neuroscience"

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  • BuChE-IN-13


    <p>BuChE-IN-13 (compound 3) is a BuChE inhibitor that exhibits anti-Alzheimers activity. It is utilized in the research of neurodegenerative diseases.</p>
    Couleur et forme :Odour Solid
  • JH-XII-03-02

    CAS :
    <p>JH-XII-03-02 is a potent and selective leucine-rich repeat kinase 2 (LRRK2) proteolysis targeting chimera (PROTAC) degrader, utilized in Parkinson's Disease (PD</p>
    Formule :C43H51N9O10
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :853.92
  • Neural Regeneration Compound Library


    <p>A unique collection of 149 neuroregeneration related compounds for high throughput and high content screening;</p>
    Couleur et forme :Odour Solid
  • Cinanserin hydrochloride

    CAS :
    <p>Cinanserin hydrochloride (SQ 10643) is a 5-HT2 receptor blocker (Ki: 41 nM) and SARS-CoV 3C-like protease inhibitor.</p>
    Formule :C20H25ClN2OS
    Degré de pureté :99.57%
    Couleur et forme :Solid
    Masse moléculaire :376.94
  • CNS-Penetrant Compound Library


    <p>A unique collection of 509 CNS-Penetrant compounds for high throughput screening (HTS) and high content screening (HCS);</p>
    Couleur et forme :Odour Solid
  • CHF-5022

    CAS :
    <p>CHF-5022 is a nonsteroidal anti-inflammatory drug that selectively inhibits the production of beta-amyloid protein (1-42) (ABETA42).</p>
    Formule :C17H12F4O2
    Couleur et forme :Solid
    Masse moléculaire :324.27
  • BChE-IN-40


    <p>BChE-IN-40 (compound D40) is a potent butyrylcholinesterase inhibitor with an IC50 of 0.59 μM. It demonstrates significant anti-inflammatory effects, with an IC50 of 4.55 μM in inhibiting nitric oxide production. Additionally, BChE-IN-40 exhibits excellent permeability across the blood-brain barrier.</p>
    Formule :C28H30N2O7
    Couleur et forme :Solid
    Masse moléculaire :506.2053
  • AChE-IN-45


    <p>AChE-IN-45 (Compound 14) is an acetylcholinesterase (AChE) inhibitor exhibiting an IC50 value of 11.57±0.45 nM, and it demonstrates both antioxidant and</p>
    Couleur et forme :Odour Solid
  • β-Amyloid (1-28)

    CAS :
    <p>β-Amyloid (1-28) is a β-Amyloid protein fragment involved in metal binding.</p>
    Formule :C145H209N41O46
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :3262.51
  • sabcomeline

    CAS :
    <p>Sabcomeline: potent, selective M1 agonist; boosts cognition; for Alzheimer's study.</p>
    Formule :C10H15N3O
    Couleur et forme :Solid
    Masse moléculaire :193.25
  • AChE/BChE-IN-14


    <p>AChE/BChE-IN-14 (compound 13), a benzylisoquinoline alkaloid extracted from Fissistigma polyanthum roots, demonstrates inhibitory effects on both</p>
    Formule :C19H23NO3
    Couleur et forme :Solid
    Masse moléculaire :313.39
  • AC1-IN-1

    CAS :
    <p>AC1-IN-1 is a selective inhibitor of adenylyl cyclase type 1 (AC1, IC50 = 0.54 µM).</p>
    Formule :C18H18FN5O2
    Degré de pureté :99.89%
    Couleur et forme :Solid
    Masse moléculaire :355.37
  • CALP2

    CAS :
    <p>CALP2 is a CaM antagonist blocking EF-hand/Ca2+ site; inhibits CaM phosphodiesterase, raises Ca2+, and activates alveolar macrophages.</p>
    Formule :C68H104N14O13S
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :1357.72
  • (±)-LY367385

    CAS :
    <p>(±)-LY367385 is the racemic form of LY367385, and LY367385 is a highly potent and selective mGluR1a antagonist.</p>
    Formule :C10H11NO4
    Couleur et forme :Solid
    Masse moléculaire :209.201
  • p-Xylene bis(pyridinium bromide)

    CAS :
    <p>p-Xylene bis(pyridinium bromide) (compound 21) is a cationic quenching agent and acts as a weak bis-quaternary ammonium salt inhibitor for AChE and BChE, with IC50 values of 1540 μM and 529 μM, respectively.</p>
    Formule :C18H18Br2N2
    Couleur et forme :Solid
    Masse moléculaire :422.16
  • (S)-3,4-DCPG

    CAS :
    <p>(S)-3,4-DCPG ((S)-3,4-Dicarboxyphenylglycine) is a selective agonist of human metabotropic glutamate receptor 8a (mGluR8a).</p>
    Formule :C10H9NO6
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :239.18
  • Methylatropine (nitrate)

    CAS :
    <p>Methylatropine: Muscarinic antagonist, &lt;0.1 nM IC50, atropine derivative, lowers ACh's effect on BP, affects salivation, pupil dilation, heart rate.</p>
    Formule :C18H26N2O6
    Couleur et forme :Solid
    Masse moléculaire :366.414
  • GSK-3β inhibitor 27


    <p>GSK-3β inhibitor27 (Compound 1c) is a reversible, competitive inhibitor of GSK-3β with an IC50 value of 2.2 μM. It inhibits tau hyperphosphorylation and reduces Aβ protein aggregation, demonstrating metal chelation and neuroprotective potential. GSK-3β inhibitor27 is promising for research into neurodegenerative diseases, such as Alzheimer's disease.</p>
    Formule :C16H17ClN4O2
    Couleur et forme :Solid
    Masse moléculaire :332.79
  • mGluR5 modulator 1

    CAS :
    <p>mGluR5 modulator 1 is a positive modulator for mGluR5, used in schizophrenia and cognitive research.</p>
    Formule :C18H19ClFN3O2
    Couleur et forme :Solid
    Masse moléculaire :363.82
  • 1H-Indole-3-carboxylic acid, 5-[2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]propoxy]-2-methyl-1-(4-methylphenyl)-, ethyl ester

    CAS :
    <p>Compound 5936-0108对β-淀粉样蛋白可能具有调节作用。</p>
    Formule :C26H34N2O7
    Degré de pureté :99.44%
    Couleur et forme :Soild
    Masse moléculaire :486.56
  • Guanylyl Imidodiphosphate (lithium salt)

    CAS :
    <p>Guanylyl Imidodiphosphate (lithium salt) is a non-hydrolyzable GTP analog that increases adenylate cyclase activity.</p>
    Formule :C10H13Li4N6O13P3
    Couleur et forme :Solid
    Masse moléculaire :545.93
  • Pozanicline hydrochloride


    <p>Pozanicline hydrochloride is an oral α4β2 nAChR agonist with a 16.7 nM Ki, insignificantly binding to α7 nAChR.</p>
    Formule :C11H17ClN2O
    Degré de pureté :97.13% - 99.81%
    Couleur et forme :Solid
    Masse moléculaire :228.72
  • Furosemide sodium

    CAS :
    <p>Furosemide sodium: potent NKCC inhibitor, loop diuretic, treats heart failure, hypertension, edema, selective GABAA antagonist.</p>
    Formule :C12H10ClN2NaO5S
    Degré de pureté :99.52% - >99.99%
    Couleur et forme :Solid
    Masse moléculaire :352.73
  • 5-MeO-pyr-T

    CAS :
    <p>5-MeO-pyr-T (5-Methoxy pyrrolidinyltryptamine) acts as a 5-HT1AR agonist, exhibiting Ki values of 0.577 μM and 373 μM for 5-HT1AR and 5-HT2AR, respectively. It inhibits the reuptake of 5-HT and triggers its release. Additionally, 5-MeO-pyr-T can induce reduced motor activity.</p>
    Formule :C15H20N2O
    Couleur et forme :Solid
    Masse moléculaire :244.33
  • ALEPH hydrochloride

    CAS :
    <p>ALEPH (hydrochloride) acts as a partial agonist of h5-HT2A and h5-HT2B receptors, with EC50 values of 10.3 nM and 19.2 nM, respectively. It can induce head twitch responses in mice, with an ED50 of 0.80 mg/kg.</p>
    Formule :C12H20ClNO2S
    Couleur et forme :Solid
    Masse moléculaire :277.81
  • Coumarinic acid

    CAS :
    <p>Coumarinic acid serves as a brain-penetrating inhibitor of AChE (acetylcholinesterase) and β-amyloid, with applications in anti-Alzheimer's drug research [1].</p>
    Formule :C9H8O3
    Couleur et forme :Solid
    Masse moléculaire :164.16
  • ECPLA

    CAS :
    <p>ECPLA is an LSD analog and a potent 5-HT2A agonist (EC50 of 14.6 nM), capable of stimulating Gq-mediated calcium flux. It exhibits high affinity for most serotonin receptors, α2-adrenergic receptors, and D2-like dopamine receptors.</p>
    Formule :C21H25N3O
    Couleur et forme :Solid
    Masse moléculaire :335.44
  • Aceclidine (hydrochloride)

    CAS :
    <p>agonist of muscarinic receptors</p>
    Formule :C9H16ClNO2
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :205.68
  • Ethylpropyltryptamine

    CAS :
    <p>Ethylpropyltryptamine (EPT) is an orally active novel psychoactive substance. It is predicted to act as a partial agonist of the 5-HT2A receptor.</p>
    Formule :C15H22N2
    Couleur et forme :Solid
    Masse moléculaire :230.35
  • 4-Hydroxy MET

    CAS :
    <p>4-Hydroxy MET (4-HO-MET) is a tryptamine-based new psychoactive substance (NPS), structurally similar to the endogenous neurotransmitter serotonin. It has hallucinogenic properties that affect mood, movement, and cognitive functions.</p>
    Formule :C13H18N2O
    Couleur et forme :Solid
    Masse moléculaire :218.3
  • Xaliproden

    CAS :
    <p>Xaliproden is a biochemical.</p>
    Formule :C24H22F3N
    Couleur et forme :Solid
    Masse moléculaire :381.43
  • Fabesetron

    CAS :
    <p>Fabesetron (FK1052): oral dual antagonist for 5-HT3/5-HT4 receptors. Aids in managing acute and delayed chemo-induced emesis.</p>
    Formule :C18H19N3O
    Couleur et forme :Solid
    Masse moléculaire :293.37
  • Calcium Channel Compound Library


    <p>A unique collection of 140 calcium channel blockers and agonists for high throughput and high content screening;</p>
    Couleur et forme :Odour Solid
  • 4-Chloromethamphetamine hydrochloride

    CAS :
    <p>4-Chloromethamphetamine hydrochloride is a novel psychoactive substance belonging to the amphetamine class.</p>
    Formule :C10H15Cl2N
    Couleur et forme :Solid
    Masse moléculaire :220.14
  • 4-fluoro MBZP

    CAS :
    <p>4-fluoro MBZP is a novel psychoactive substance in the phenylpiperazine class, utilized for studies on the 5-HT2 receptors in the central nervous system.</p>
    Formule :C12H17FN2
    Couleur et forme :Solid
    Masse moléculaire :208.28
  • Lanuginosine

    CAS :
    <p>Lanuginosine, an aporphine alkaloid, exhibits cytotoxicity against U251.</p>
    Formule :C18H11NO4
    Couleur et forme :Solid
    Masse moléculaire :305.28
  • RS 56812

    CAS :
    <p>RS 56812 is a 5-HT3 receptor antagonist and agonist used in the study of cognitive disorders.</p>
    Formule :C18H21N3O2
    Degré de pureté :99.38%
    Couleur et forme :Soild
    Masse moléculaire :311.38
  • 5-HT2C agonist-4

    CAS :
    <p>Compound 3i, a 5-HT2C agonist-4, acts as an agonist for the 5-HT2C receptor with an EC50 of 5.7 nM. It is capable of reducing locomotor activity in zebrafish larvae.</p>
    Formule :C24H25N5O
    Couleur et forme :Solid
    Masse moléculaire :399.49
  • Orexin A (human, rat, mouse) (TFA)


    <p>Endogenous orexin receptor agonist with Ki of 20 nM (OX1) and 38 nM (OX2), promotes feeding, may regulate sleep-wake cycle.</p>
    Formule :C154H244N47F3O46S4
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :3675.12
  • DOAM

    CAS :
    <p>DOAM is an antagonist of the 5-HT2 receptor.</p>
    Formule :C16H27NO2
    Couleur et forme :Solid
    Masse moléculaire :265.39
  • L-AP3

    CAS :
    <p>L-AP3 blocks mGluR, inhibits D/L-phosphoserine (IC50: 368/2087 μM).</p>
    Formule :C3H8NO5P
    Couleur et forme :White Hygroscopic Solid
    Masse moléculaire :169.073
  • BChE-IN-19


    <p>BChE-IN-19 (Compound 7b), a para-substituted indone derivative, exhibits potent inhibitory activity against butyryl cholinesterase (BChE) with an IC50 value of</p>
    Formule :C25H31NO5
    Couleur et forme :Solid
    Masse moléculaire :425.52
  • 4-Methoxyphenyl isothiocyanate

    CAS :
    <p>4-Methoxyphenyl isothiocyanate (4-Methylphenyl ITC) is recognized as an antioxidant demonstrating an IC50 of 1.25 mM for scavenging DPPH free radicals. Its antioxidant capacity, as shown by the ORAC test, is 11.7 mM TE, equivalent to the efficacy of 11.7 mmol Trolox under similar conditions. Additionally, it extends the oxidation process in the Briggs–Rauscher reaction by approximately 9180 seconds. The compound also exhibits moderate cholinesterase inhibitory activity, with an inhibition rate of 30.4% for acetylcholinesterase (AChE) and 17.9% for butyrylcholinesterase (BChE). Research suggests 4-Methoxyphenyl isothiocyanate holds promise for applications in antioxidant and neurological disorder studies.</p>
    Formule :C8H7NOS
    Couleur et forme :Solid
    Masse moléculaire :165.21
  • (1S,3R)-3-Aminocyclopentane carboxylic acid

    CAS :
    <p>(1S,3R)-3-Aminocyclopentane carboxylic acid exhibits activity on GABAA receptors.</p>
    Formule :C6H11NO2
    Couleur et forme :Solid
    Masse moléculaire :129.16
  • Zalospirone

    CAS :
    <p>Zalospirone is a 5-HT1A receptor agonist that can be used to study anxiety disorders and major depressive disorder.</p>
    Formule :C24H29N5O2
    Degré de pureté :98.41% - 99.82%
    Couleur et forme :Solid
    Masse moléculaire :419.52
  • Calmodulin-Dependent Protein Kinase II (281-309)

    CAS :
    <p>Calmodulin-Dependent Protein Kinase II (281-309) is a synthetic peptide that can be phosphorylated at Thr286 by PKC and inhibits CaM kinase II (IC50 = 80 nM).</p>
    Formule :C146H254N46O39S3
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :3374.06
  • Triazolomethylindole-3-acetic acid

    CAS :
    <p>Triazolomethylindole-3-acetic acid is a metabolite of Rizatriptan, which acts as an agonist for the serotonin (5-HT) receptor subtypes 5-HT1B and 5-HT1D.</p>
    Formule :C13H12N4O2
    Couleur et forme :Solid
    Masse moléculaire :256.26
  • α-Conotoxin AuIB

    CAS :
    <p>Selective antagonist of α3β4 nicotinic acetylcholine receptors.</p>
    Formule :C65H89N17O21S4
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :1572.76
  • Serotonin Receptor-Targeted Compound Library


    <p>A unique collection of xnum compounds targeting serotonin receptors for high throughput screening and high content screening;</p>
    Couleur et forme :Odour Solid
  • (R)-Citalopram oxalate

    CAS :
    <p>(R)-Citalopram oxalate is a weak selective serotonin reuptake inhibitor (SSRI) that antagonises its S-isomer (escitalopram), anticonvulsant and antidepressant</p>
    Formule :C22H23FN2O5
    Degré de pureté :99.76%
    Couleur et forme :White Solid
    Masse moléculaire :414.43
  • β-Secretase Inhibitor I

    CAS :
    <p>β-Secretase Inhibitor I is a highly potent inhibitor of the β-secretase enzyme.</p>
    Formule :C18H18F3N5O2S
    Couleur et forme :Solid
    Masse moléculaire :425.43
  • TET-13


    <p>TET-13 is a positive allosteric modulator of the GABAA receptor with an EC50 of 5.65 μM, which is more potent than Etomidate (EC50: 9.29 μM). It exhibits strong anesthetic effects in both mice and rats, with an ED50 of 0.48 mg/kg in mice and 0.69 mg/kg in rats.</p>
    Formule :C15H16N2O3S
    Couleur et forme :Solid
    Masse moléculaire :304.36
  • AChE/BChE-IN-13


    <p>AChE/BChE-IN-13 (compound 5j) serves as a potent dual inhibitor of both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), exhibiting half-maximal</p>
    Formule :C21H18N8O7
    Couleur et forme :Solid
    Masse moléculaire :494.42
  • 2-(2-(1-Benzylpiperidin-4-yl)ethyl)isoindoline-1,3-dione

    CAS :
    <p>2-(2-(1-Benzylpiperidin-4-yl)ethyl)isoindoline-1,3-dione exhibits acetylcholinesterase inhibitory activity with an IC50 of 0.08 µM.</p>
    Formule :C22H24N2O2
    Degré de pureté :99.41%
    Masse moléculaire :348.44
  • β-Amyloid (10-20)

    CAS :
    <p>Amyloid β-Protein (10-20) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Amyloid β protein fragment containing the α-</p>
    Formule :C71H99N17O16
    Degré de pureté :98%
    Couleur et forme :Lyophilized Powder
    Masse moléculaire :1446.65
  • 2-Methyl-N,N-dimethyltryptamine

    CAS :
    <p>2-Methyl-N,N-dimethyltryptamine (2,N,N-TMT, compound 15) exhibits binding affinity for the serotonin (5-HT) receptor, with a pA2 value of 6.04. It plays a significant role in neurological disease research.</p>
    Formule :C13H18N2
    Couleur et forme :Solid
    Masse moléculaire :202.3
  • MAO-B-IN-20


    <p>MAO-B-IN-20, potent with 0.037 μM IC50, is stable and BBB permeable, useful for Parkinson's research.</p>
    Formule :C20H18F2N2O2
    Couleur et forme :Solid
    Masse moléculaire :356.37
  • Neurotransmitter Receptor Compound Library


    <p>A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening;</p>
    Couleur et forme :Odour Solid
  • LY3027788

    CAS :
    <p>LY3027788, potent oral prodrug of LY3020371, is a strong mGlu2/3 antagonist with notable antidepressant effects.</p>
    Formule :C25H31F2NO11S
    Couleur et forme :Solid
    Masse moléculaire :591.58
  • Substance P(1-4) Acetate


    <p>Substance P(1-4) Acetate is a neurokinin receptor (NK-R) antagonist, inhibiting the formation of PV EEC.</p>
    Formule :C24H44N8O7
    Degré de pureté :99.84%
    Couleur et forme :Solid
    Masse moléculaire :556.66
  • Cannabidiolic acid methyl ester

    CAS :
    <p>Cannabidiolic acid methyl ester (HU-580) is an orally active analogue of cannabidiolic acid. It enhances the activation of 5-HT1A receptors and increases the expression of c-Fos and NeuN in specific hypothalamic nuclei in rats. Cannabidiolic acid methyl ester exhibits anti-nausea, anxiolytic, and anti-nociceptive effects.</p>
    Formule :C23H32O4
    Couleur et forme :Solid
    Masse moléculaire :372.5
  • LY3027788 hydrochloride

    CAS :
    <p>LY3027788 HCl, potent oral prodrug of LY3020371, targets mGlu2/3 with antidepressant effects.</p>
    Formule :C25H32ClF2NO11S
    Couleur et forme :Solid
    Masse moléculaire :628.03
  • 5-HT2A receptor agonist-5

    CAS :
    <p>5-HT2A receptor agonist-5 (compound I-3) is a potent 5-HT2A agonist with a Ki value of 0.017 µM and exhibits antidepressant activity.</p>
    Formule :C23H29N3O
    Couleur et forme :Solid
    Masse moléculaire :363.5
  • Paynantheine

    CAS :
    <p>Paynantheine is an alkaloid with antinociceptive properties, found in Mitragyna speciosa. It also acts as an agonist at 5-HT1AR and 5-HT2BR receptors, inducing lower lip contraction and providing antinociception in rats.</p>
    Formule :C23H28N2O4
    Couleur et forme :Solid
    Masse moléculaire :396.48
  • VU0483605

    CAS :
    <p>VU0483605 is an effective and selective positive allosteric modulator of mGluR1 with EC50s of 390 and 356 nM for human and rat, respectively.</p>
    Formule :C20H10Cl3N3O3
    Degré de pureté :99.61%
    Couleur et forme :Solid
    Masse moléculaire :446.67
  • Nitrazolam

    CAS :
    <p>Nitrazolam is a benzodiazepine compound that may exhibit central nervous system depressant properties similar to traditional benzodiazepine drugs by acting on the GABA receptors (GABA receptor). These effects include sedation, hypnosis, anxiolytic, and anticonvulsant activities.</p>
    Formule :C17H13N5O2
    Couleur et forme :Solid
    Masse moléculaire :319.32
  • (rel)-Asperparaline A

    CAS :
    <p>Aspergillimide, from A. japonicus, inhibits silkworm neuron nAChRs (IC50s: 20.2/39.6 nM), not affecting chicken nAChRs, and paralyzes silkworm larvae.</p>
    Formule :C20H29N3O3
    Couleur et forme :Solid
    Masse moléculaire :359.47
  • Fasciculic acid C

    CAS :
    <p>Fasciculic acid C is a calmodulin antagonist isolated from mushroom Naematoloma fasciculare.</p>
    Formule :C38H63NO11
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :709.91
  • β-Amyloid (22-35)

    CAS :
    <p>β-Amyloid (22-35) is a 14-aa peptide, shows aggregates and induces neurotoxicity in the hippocampal cells.</p>
    Formule :C59H102N16O21S
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :1403.62
  • 4-Iodoamphetamine hydrochloride

    CAS :
    <p>4-Iodoamphetamine (p-Iodoamphetamine) hydrochloride is a halogenated phenethylamine characterized by the presence of an iodine atom at the para position of the phenyl group. It selectively induces serotonin release and inhibits reuptake in rat brain synaptosomes.</p>
    Formule :C9H13ClIN
    Couleur et forme :Solid
    Masse moléculaire :297.56
  • 5-HT1AR agonist 2


    <p>5-HT1AR Agonist 2 (Compound 4f) is a potent agonist of the 5-HT1A receptor with a Ki value of 10.0 nM. It also binds to SERT, D2, and 5-HT6 receptors with Ki values of 2.8 nM, 23 nM, and 192 nM, respectively. Furthermore, this compound demonstrates stability in microsomes and induces hypothermia in mice.</p>
    Formule :C31H31N5O3
    Couleur et forme :Solid
    Masse moléculaire :521.61
  • bPiDDB

    CAS :
    <p>bPiDDB (N,N'-Dodecylbis-Picolinium Bromide) is a nicotinic receptor (nAChR) antagonist.</p>
    Formule :C24H38Br2N2
    Degré de pureté :98.72%
    Couleur et forme :Solid
    Masse moléculaire :514.38
  • Anabaseine

    CAS :
    <p>Anabaseine is a broad nicotinic agonist, favoring alpha-7 AChRs in muscle/brain, and weakly stimulates alpha-4 beta-2 nAChRs.</p>
    Formule :C10H12N2
    Couleur et forme :Solid
    Masse moléculaire :160.22
  • AChE/BChE-IN-26


    <p>AChE/BChE-IN-26 (Compound 20aa) is a cholinesterase inhibitor with IC50 values of 0.75 μM for eeAChE and 4.11 μM for eqBChE. This compound possesses antioxidant properties and is applicable in research related to diseases such as Alzheimer's.</p>
    Couleur et forme :Odour Solid
  • JNJ-67569762

    CAS :
    <p>JNJ-67569762 is a selective BACE1 inhibitor targeting the S3 pocket ( IC 50 = 2.7 nM).</p>
    Formule :C22H22F4N4O5S
    Couleur et forme :Solid
    Masse moléculaire :530.49
  • AHN-683

    CAS :
    <p>AHN-683 is a fluorescent ligand. It was used for peripheral-type benzodiazepine receptors.</p>
    Formule :C42H32FN3O7
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :709.72
  • PF-03382792

    CAS :
    <p>PF-03382792 is a small molecule 5-HT4 receptor activator for the study of Alzheimer's disease.</p>
    Formule :C23H32FN3O4
    Degré de pureté :99.64%
    Couleur et forme :Solid
    Masse moléculaire :433.52
  • [Ala11,D-Leu15]-Orexin B acetate


    <p>[Ala11,D-Leu15]-Orexin B acetate is a selective agonist of orexin-2 receptor (OX2) with an EC50 of 0.13 nM, showing 400-fold selectivity over OX1 (52 nM).</p>
    Formule :C122H210N44O37S
    Degré de pureté :98.18%
    Couleur et forme :Solid
    Masse moléculaire :2917.31
  • DCCCyb

    CAS :
    <p>DCCCyb: oral GlyT1 inhibitor with high in vivo occupancy in rhesus monkeys, confirmed by PET tracer displacement.</p>
    Formule :C22H29Cl2NO3S
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :458.44
  • Isonaringin

    CAS :
    <p>Isonaringin shows anti-Alzheimer’s activity by inhibiting AChE.</p>
    Formule :C27H32O14
    Couleur et forme :Solid
    Masse moléculaire :580.53
  • Minaprine

    CAS :
    <p>Minaprine is a reversible inhibitor of MAO-A, used in the treatment of various depressive states.</p>
    Formule :C17H22N4O
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :298.38
  • Tiflucarbine

    CAS :
    <p>Tiflucarbine is a potential non-selective 5-HT agonist with antidepressant activity.Tiflucarbine dose-dependently increased the specific activity of soluble</p>
    Formule :C16H17FN2S
    Degré de pureté :>99.99%
    Couleur et forme :Solid
    Masse moléculaire :288.38
  • Dipentylone hydrochloride

    CAS :
    <p>Dipentylone hydrochloride (Bk-dmbdp HCl) is a psychoactive synthetic cathinone and sympathomimetic stimulant. Its inhibitory activity towards the dopamine transporter (IC50=0.233µM) is tenfold higher than that towards NET and SERT, inhibiting dopamine uptake and stimulating locomotor activity in mice.</p>
    Formule :C14H20ClNO3
    Degré de pureté :99.94%
    Couleur et forme :Solid
    Masse moléculaire :285.77
  • pCPA methyl ester hydrochloride

    CAS :
    <p>pCPA methyl ester HCl inhibits tryptophan hydroxylase, 5-HT synthesis, crosses blood-brain barrier, lowers central 5-HT.</p>
    Formule :C10H13Cl2NO2
    Degré de pureté :99.73% - 99.88%
    Couleur et forme :Solid
    Masse moléculaire :250.12
  • PSEN1-IN-2


    <p>PSEN1-IN-2 (Compound 13K) is a potent inhibitor of both PSEN1-APH1A and PSEN1-APH1B complexes, exhibiting IC50 values of 6.9 nM and 2.4 nM, respectively.</p>
    Formule :C20H18ClFN2O3S
    Couleur et forme :Solid
    Masse moléculaire :420.88
  • Pyridostigmine bromide

    CAS :
    <p>Pyridostigmine bromide (Mestinon), a cholinesterase inhibitor, is used in the treatment of myasthenia gravis and to reverse the actions of muscle relaxants.</p>
    Formule :C9H13BrN2O2
    Degré de pureté :99.00% - 99.98%
    Couleur et forme :White Or Practically White Crystalline Powder Pale Yellow To Colorless Liquid
    Masse moléculaire :261.12
  • Exosome Compound Library


    <p>76 exosome-related compounds that can be used for high-throughput and high-content screening.</p>
    Couleur et forme :Odour Solid
  • Serazapine

    CAS :
    <p>Serazapine is a highly specific serotonin (5-HT2) binding inhibitor with anxiolytic activity for the treatment of anxiety disorders.</p>
    Formule :C22H23N3O2
    Degré de pureté :98.71% - 99.57%
    Couleur et forme :Solid
    Masse moléculaire :361.44
  • Femoxetine

    CAS :
    <p>Femoxetine: antidepressant, enhances morphine, inhibits MAO-A/B, boosts mice's exercise capacity.</p>
    Formule :C20H25NO2
    Degré de pureté :99.1% - 99.35%
    Couleur et forme :Solid
    Masse moléculaire :311.42
  • Inaperisone

    CAS :
    <p>Inaperisone: a novel muscle relaxant that indirectly inhibits voiding reflex via brainstem GABAB receptors.</p>
    Formule :C16H23NO
    Degré de pureté :99.48%
    Couleur et forme :Solid
    Masse moléculaire :245.36
  • Bencycloquidium Bromide

    CAS :
    <p>Bencycloquidium bromide is an M3 muscarinic antagonist that reduces nasal secretion in allergic rhinitis and has high affinity for M3 receptors.</p>
    Formule :C21H32BrNO2
    Couleur et forme :Solid
    Masse moléculaire :410.39
  • Adatanserin hydrochloride

    CAS :
    <p>Adatanserin hydrochloride (WY50324 hydrochloride) is a 5-HT(1A)/5-HT(2) receptor ligand that is neuroprotective and may be used in the study of depression.</p>
    Formule :C21H32ClN5O
    Degré de pureté :99.64%
    Couleur et forme :Solid
    Masse moléculaire :405.96
  • γ-DGG TFA

    CAS :
    <p>Gamma-DGG TFA is an antagonist of excitatory amino acids that can inhibit depolarization induced by NMDA, Kainate, and Quisqualate. In addition, it counteracts excitatory postsynaptic potentials (e.p.s.p.) in rat hippocampal slices.</p>
    Formule :C9H13F3N2O7
    Couleur et forme :Solid
    Masse moléculaire :318.2
  • AChE/BChE-IN-22


    <p>AChE/BChE-IN-22 (compound 7) exhibits competitive inhibition against both AChE and BChE enzymes, with inhibition constants of 28.18 μM and 41.74 μM respectively.</p>
    Formule :C14H11F3N2O4S
    Couleur et forme :Solid
    Masse moléculaire :360.31
  • Brexanolone caprilcerbate

    CAS :
    <p>Brexanolone caprilcerbate is an effective positive allosteric modulator of the GABAA receptor.</p>
    Formule :C48H78O12
    Couleur et forme :Solid
    Masse moléculaire :847.13
  • MMPIP hydrochloride

    CAS :
    <p>MMPIP hydrochloride is a selective antagonist of allosteric mGluR7.</p>
    Formule :C19H16ClN3O3
    Degré de pureté :99.88%
    Couleur et forme :Solid
    Masse moléculaire :369.8
  • 5-AMAM-2-CP

    CAS :
    <p>5-AMAM-2-CP, a significant metabolite of Acetamiprid, serves as a global insecticide within the neonicotinoid class and acts as an nAChR agonist [1] [2].</p>
    Formule :C9H11ClN2O
    Couleur et forme :Solid
    Masse moléculaire :198.65
  • (Rac)-Norcisapride

    CAS :
    <p>Norcisapride, a 5-HT3 and 5-HT4 agonist, treats GI, orofacial, and ENT disorders.</p>
    Formule :C14H20ClN3O3
    Degré de pureté :99.32%
    Couleur et forme :Soild
    Masse moléculaire :313.78
  • Cianopramine hydrochloride

    CAS :
    <p>Cianopramine hydrochloride is a bio-active chemical.</p>
    Formule :C20H24ClN3
    Couleur et forme :Solid
    Masse moléculaire :341.88
  • Tetrahydro-β-carboline

    CAS :
    <p>Compound Fr12161, with CAS No. 16502-01-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr12161 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>
    Formule :C11H12N2
    Degré de pureté :96.31%
    Couleur et forme :Tan Solid
    Masse moléculaire :172.2264