Neuroscience
Les inhibiteurs en neurosciences sont des composés conçus pour moduler l'activité de protéines, d'enzymes ou de récepteurs spécifiques au sein du système nerveux. Ces inhibiteurs sont cruciaux pour étudier les mécanismes moléculaires sous-jacents au fonctionnement neuronal, à la transmission synaptique et aux maladies neurodégénératives. En ciblant les récepteurs des neurotransmetteurs, les canaux ioniques et les voies de signalisation, les inhibiteurs en neurosciences facilitent l'exploration du fonctionnement cérébral et le développement de stratégies thérapeutiques pour des troubles neurologiques tels que la maladie d'Alzheimer, de Parkinson et l'épilepsie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs en neurosciences de haute qualité pour soutenir vos recherches en neurobiologie, neuropharmacologie et sciences cognitives.
Sous-catégories appartenant à la catégorie "Neuroscience"
- récepteur 5-HT(1.025 produits)
- ACK(1 produits)
- AChR(647 produits)
- ATP Citrate Lyase(17 produits)
- Récepteur adrénergique(3.028 produits)
- BACE(37 produits)
- Bêta-amyloïde(231 produits)
- CaMK(73 produits)
- COX(602 produits)
- Récepteur de la dopamine(445 produits)
- Récepteur GABA(373 produits)
- Gamma-sécrétase(62 produits)
- GluR(265 produits)
- GlyT(26 produits)
- Récepteur de l'histamine(385 produits)
- LRRK2(42 produits)
- Récepteur de la mélatonine(26 produits)
- NMDAR(10 produits)
- Récepteur OX(41 produits)
- Récepteur opioïde(327 produits)
Affichez 12 plus de sous-catégories
5638 produits trouvés pour "Neuroscience"
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Dapoxetine
CAS :Dapoxetine (Dapoxetina) is a selective serotonin reuptake inhibitor, for the treatment of premature ejaculation.Formule :C21H23NODegré de pureté :99.73%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :305.4212,14-Dichlorodehydroabietic acid
CAS :12,14-Dichlorodehydroabietic acid activates BK channels, blocks GABA A receptors, and increases calcium and neurotransmitter release.Formule :C20H26Cl2O2Couleur et forme :SolidMasse moléculaire :369.33SAHM1
CAS :Notch pathway inhibitor - stabilized hydrocarbon-stapled alpha helical peptide. Targets the protein-protein interface and prevents Notch complex assembly.Formule :C94H162N36O23SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :2196.58IHC3
IHC3 is a competitive and reversible monoamine oxidase B (MAO-B) inhibitor with an IC50 of 1.672 μM, which targets Cys172 within the enzyme's active site.Formule :C17H12FN3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :293.3DSP-1053
CAS :Dsp-1053 is a powerful SERT (Ki=1.02 nM) inhibitor with partial 5-HT1A receptor (Ki=5.05 nM) agonizing activity.Formule :C26H32BrNO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :502.44hAChE/hBuChE/GSK-3β-IN-1
hAChE/hBuChE/GSK-3β-IN-1 (Compound 6c) is a multi-target compound designed for Alzheimer's treatment capable of crossing the blood-brain barrier. It inhibits hAChE with an IC50 of 28.88 nM, hBuChE with an IC50 of 131.90 nM, and GSK-3β with an IC50 of 51.42 nM. Additionally, it acts as an inhibitor of tau protein and Aβ protein aggregation.Formule :C19H15NO4Couleur et forme :SolidMasse moléculaire :321.327Ethylpropyltryptamine
CAS :Ethylpropyltryptamine (EPT) is an orally active novel psychoactive substance. It is predicted to act as a partial agonist of the 5-HT2A receptor.Formule :C15H22N2Couleur et forme :SolidMasse moléculaire :230.35MAO-B-IN-38
MAO-B-IN-38 (Compound 6b) is a reversible, competitive inhibitor of MAO-B, exhibiting IC50 values of 0.03 µM for MAO-B and 21.46 µM for MAO-A. This compound is applicable in research on neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease.Formule :C14H17FN4O2S3Couleur et forme :SolidMasse moléculaire :388.504PSEN1-IN-2
PSEN1-IN-2 (Compound 13K) is a potent inhibitor of both PSEN1-APH1A and PSEN1-APH1B complexes, exhibiting IC50 values of 6.9 nM and 2.4 nM, respectively.Formule :C20H18ClFN2O3SCouleur et forme :SolidMasse moléculaire :420.88Azocarnil
Azocarnil is a GABAergic agonist-enhancer used in neurological system research.Couleur et forme :Odour SolidFFN246
CAS :FFN246, a fluorescent probe, concurrently targets the serotonin transporter (SERT) and vesicular monoamine transporter 2 (VMAT2), exhibiting excitation andFormule :C15H13FN2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :256.27PD10
PD10 is a dual inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE), exhibiting inhibitory potency at human AChE (hAChE IC50: 0.56 μM),Formule :C23H21BrN2O4Couleur et forme :SolidMasse moléculaire :469.33Dipentylone hydrochloride
CAS :Dipentylone hydrochloride (Bk-dmbdp HCl) is a psychoactive synthetic cathinone and sympathomimetic stimulant. Its inhibitory activity towards the dopamine transporter (IC50=0.233µM) is tenfold higher than that towards NET and SERT, inhibiting dopamine uptake and stimulating locomotor activity in mice.Formule :C14H20ClNO3Degré de pureté :99.94%Couleur et forme :SolidMasse moléculaire :285.77Nipecotic acid
CAS :Compound PDK0243, with CAS No. 498-95-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0243 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.
Formule :C6H11NO2Couleur et forme :Off-White To Pale Yellow-Beige PowderMasse moléculaire :129.16AChE-IN-43
AChE-IN-43 is a potent, selective AChE inhibitor with a K i of 0.41 μM, applicable in the study of neurological diseases [1].Couleur et forme :Odour SolidRAGE antagonist peptide
CAS :RAGE antagonist blocks S100P/A4, HMGB-1; hinders glioma growth, metastasis; reduces PDAC cell growth, NF-κB activity; counters TDI effects in mice.Formule :C57H101N13O17SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1272.56Bensultap
CAS :Bensultap is an agricultural chemical typically used as a pesticide.Formule :C17H21NO4S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :431.61Bleformin A
CAS :Bleformin A, a natural BChE inhibitor from Bletilla striata, has a 5.2 μM IC50 and is studied for Alzheimer's research.Formule :C23H20O5Couleur et forme :SolidMasse moléculaire :376.4Isonaringin
CAS :Isonaringin shows anti-Alzheimer’s activity by inhibiting AChE.
Formule :C27H32O14Couleur et forme :SolidMasse moléculaire :580.53DCCCyb
CAS :DCCCyb: oral GlyT1 inhibitor with high in vivo occupancy in rhesus monkeys, confirmed by PET tracer displacement.Formule :C22H29Cl2NO3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :458.44ECPLA
CAS :ECPLA is an LSD analog and a potent 5-HT2A agonist (EC50 of 14.6 nM), capable of stimulating Gq-mediated calcium flux. It exhibits high affinity for most serotonin receptors, α2-adrenergic receptors, and D2-like dopamine receptors.Formule :C21H25N3OCouleur et forme :SolidMasse moléculaire :335.44Osmanthuside B
CAS :Osmanthuside B, isolated from Pseuderanthemum carruthersii (Seem.) Guill.Formule :C29H36O13Couleur et forme :SolidMasse moléculaire :592.59AChE/BuChE-IN-4
CAS :AChE/BuChE-IN-4 is a multi-target AChE/BuChE inhibitor with IC50 values of 2.08 and 7.41 μM for AChE and BuChE, respectively.Formule :C17H23N5Degré de pureté :99.98%Couleur et forme :SoildMasse moléculaire :297.4β-Amyloid (1-16)
CAS :β-Amyloid (1-16) is an amyloidogenic protein fragment with a sequence derived from β-amyloid.Formule :C84H119N27O28Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1955.04β-Amyloid (13-27)
CAS :β-Amyloid (13-27) is a peptide consisting of amino acid of 13 to 27 of beta amyloid protein.Formule :C84H126N24O24Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1856.05HDAC6-IN-49
HDAC6-IN-49 (Compound 3) is an inhibitor of HDAC, with IC50 values of 0.012 and 0.735 µM against HDAC6 and HDAC1, respectively. Additionally, it inhibits MAO-B, cholinesterase (ChE), histamine receptor (H3R), and serotonin 6 receptor (5-HT6R). HDAC6-IN-49 exhibits neuroprotective effects in SH-SY5Y cells and enhances cognitive functions and motor abilities in fruit fly models of Parkinson's disease and C. elegans models of Alzheimer's disease.Couleur et forme :Odour Solid(S,S)-BMS-984923
CAS :(S,S)-BMS-984923 is a weak mGluR5 modulator with EC50 >1μM; less active than its potent counterpart.Formule :C22H15ClN2O2Couleur et forme :SolidMasse moléculaire :374.82Alosetron
CAS :Alosetron, a 5-HT3 antagonist, is used for the management of severe diarrhea-predominant irritable bowel syndrome (IBS) in women only.Formule :C17H18N4ODegré de pureté :98%Couleur et forme :Crystalline PowderMasse moléculaire :294.36Pyridostigmine bromide
CAS :Pyridostigmine bromide (Mestinon), a cholinesterase inhibitor, is used in the treatment of myasthenia gravis and to reverse the actions of muscle relaxants.Formule :C9H13BrN2O2Degré de pureté :99.00% - 99.98%Couleur et forme :White Or Practically White Crystalline Powder Pale Yellow To Colorless LiquidMasse moléculaire :261.12Mant-GTPγS
CAS :Mant-GTPγS, an effective GTP analog, displays strong competitive inhibition of adenylyl cyclase (AC). Additionally, it acts as a potent inhibitor of YdeH.Formule :C18H23N6O14P3SCouleur et forme :SolidMasse moléculaire :672.39Galanin (1-15) (porcine, rat)
CAS :N-terminal galanin fragment used to mediate central cardiovascular effectsFormule :C72H105N19O20Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1556.72Velnacrine
CAS :Velnacrine (1,2,3,4-tetrahydro-9-aminoacridin-1-ol maleate) is a biochemical.Formule :C13H14N2ODegré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :214.26AChE/BChE-IN-26
AChE/BChE-IN-26 (Compound 20aa) is a cholinesterase inhibitor with IC50 values of 0.75 μM for eeAChE and 4.11 μM for eqBChE. This compound possesses antioxidant properties and is applicable in research related to diseases such as Alzheimer's.Couleur et forme :Odour SolidStacofylline
CAS :Stacofylline is a xanthine derivative that is used to treat migraine headaches.Formule :C20H33N7O3Degré de pureté :99.43% - 99.85%Couleur et forme :SolidMasse moléculaire :419.52Profenofos
CAS :Profenofos is an organophosphate insecticide used in cotton and vegetables. that causes neurotoxicity through the inhibition of AChE activity.Formule :C11H15BrClO3PSDegré de pureté :97.04% - 97.24%Couleur et forme :SolidMasse moléculaire :373.63β-Amyloid (22-40)
CAS :This synthetic peptide consists of amino acids 22 to 40 of beta amyloid protein.Formule :C78H135N21O26SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1815.1bPiDDB
CAS :bPiDDB (N,N'-Dodecylbis-Picolinium Bromide) is a nicotinic receptor (nAChR) antagonist.
Formule :C24H38Br2N2Degré de pureté :98.72%Couleur et forme :SolidMasse moléculaire :514.38β-Amyloid (22-35)
CAS :β-Amyloid (22-35) is a 14-aa peptide, shows aggregates and induces neurotoxicity in the hippocampal cells.Formule :C59H102N16O21SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1403.62[Ala11,D-Leu15]-Orexin B acetate
[Ala11,D-Leu15]-Orexin B acetate is a selective agonist of orexin-2 receptor (OX2) with an EC50 of 0.13 nM, showing 400-fold selectivity over OX1 (52 nM).Formule :C122H210N44O37SDegré de pureté :98.18%Couleur et forme :SolidMasse moléculaire :2917.31ALEPH hydrochloride
CAS :ALEPH (hydrochloride) acts as a partial agonist of h5-HT2A and h5-HT2B receptors, with EC50 values of 10.3 nM and 19.2 nM, respectively. It can induce head twitch responses in mice, with an ED50 of 0.80 mg/kg.Formule :C12H20ClNO2SCouleur et forme :SolidMasse moléculaire :277.81Neocarzinostatin
CAS :Neocarzinostatin is an effective DNA-damaging, anti-tumor antibiotic.Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :N/Aβ-Amyloid (1-16) acetate
β-Amyloid (1-16) acetate, Fragment of β-Amyloid, N-terminal amino group coordinates metal ions (Cu/Zn), used for Alzheimer's disease research.Formule :C84H119N27O28·xC2H4O2Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :1955.04 (free base)Fasciculic acid C
CAS :Fasciculic acid C is a calmodulin antagonist isolated from mushroom Naematoloma fasciculare.Formule :C38H63NO11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :709.91AChE-IN-40
AChE-IN-40 (Compound 5C), with an inhibitory concentration 50 (IC50) of 120 nM, is an acetylcholinesterase (AChE) inhibitor suitable for Alzheimer's diseaseFormule :C23H27NO4Couleur et forme :SolidMasse moléculaire :381.462,6-DMA hydrochloride
CAS :2,6-DMA hydrochloride is a phenethylamine and acts as an agonist of the serotonin 5-HT2 receptor, with a pA2 value of 5.09.Formule :C11H18ClNO2Couleur et forme :SolidMasse moléculaire :231.72(rel)-Asperparaline A
CAS :Aspergillimide, from A. japonicus, inhibits silkworm neuron nAChRs (IC50s: 20.2/39.6 nM), not affecting chicken nAChRs, and paralyzes silkworm larvae.
Formule :C20H29N3O3Couleur et forme :SolidMasse moléculaire :359.47GABA-A Receptor Ligand-1
GABA-A Receptor Ligand-1 (Compound 4) is a ligand for the GABA-A receptor with a pKi of 7.27. It alleviates mitochondrial dysfunction, promotes neurite outgrowth and neuronal regeneration, and demonstrates neuroprotective effects in a rat ischemic stroke model.Formule :C20H20FN3OCouleur et forme :SolidMasse moléculaire :337.391Nictide
CAS :Nictide, a peptide substrate for LRRK2 (leucine-rich repeat protein kinase-2), undergoes phosphorylation by the activated form of LRRK2[G2019S], exhibiting a Km value of 10 μM.Formule :C123H193N45O28Couleur et forme :SolidMasse moléculaire :2750.13JNJ-67569762
CAS :JNJ-67569762 is a selective BACE1 inhibitor targeting the S3 pocket ( IC 50 = 2.7 nM).Formule :C22H22F4N4O5SCouleur et forme :SolidMasse moléculaire :530.49LPYFD-NH2
CAS :neuroprotective peptide that binds to amyloid beta (Aβ)Formule :C33H44N6O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :652.74Serazapine
CAS :Serazapine is a highly specific serotonin (5-HT2) binding inhibitor with anxiolytic activity for the treatment of anxiety disorders.
Formule :C22H23N3O2Degré de pureté :98.71% - 99.57%Couleur et forme :SolidMasse moléculaire :361.44trans-Cevimeline hydrochloride
CAS :AF 102A hydrochloride is a biochemical.Formule :C10H18ClNOSCouleur et forme :SolidMasse moléculaire :235.77TC-2216
CAS :TC-2216 is a partial agonist at the neural nicotinic acetylcholine receptor and is used to treat anxiety and depression.Formule :C12H17N3Degré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :203.28(R,R)-Palonosetron Hydrochloride
CAS :(R,R)-Palonosetron Hydrochloride is the active enantiomer of PalonosetronFormule :C19H25ClN2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :332.87Donitriptan hydrochloride
CAS :Donitriptan hydrochloride (Donitriptan monohydrochloride) is a potent, high efficacy agonist of 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectivelyFormule :C23H26ClN5O2Degré de pureté :99.8% - 99.86%Couleur et forme :SolidMasse moléculaire :439.94Ref: TM-T21666
500mgÀ demander2mg40,00€5mg49,00€10mg64,00€25mg135,00€50mg240,00€100mg339,00€200mg439,00€Rovalpituzumab MMAE
Rovalpituzumab-MMAE (Anti-DLL3 Reference Antibody), produced in CHO cells, consists of a huIgG1 heavy chain and a hukappa light chain. The molecular weight of this antibody is predicted to be 145.02 kDa.Couleur et forme :LiquidMasse moléculaire :145 kDaBACE1-IN-6
CAS :BACE1-IN-6 is a BACE1 inhibitor with an IC 50 value of 1.5 nM.Formule :C25H23F2N5O2SCouleur et forme :SolidMasse moléculaire :495.55RBPJ Inhibitor-1
CAS :RBPJ Inhibitor-1 (RIN1), a compound that impedes the functional interaction between RBPJ and SHARP, effectively inhibits NOTCH-dependent tumor cellFormule :C17H14FN3O2Degré de pureté :99.79%Couleur et forme :SoildMasse moléculaire :311.31Ref: TM-T35566
1mg38,00€2mg50,00€5mg84,00€1mL*10mM (DMSO)93,00€10mg130,00€25mg215,00€50mg371,00€100mg537,00€5-MeO-pyr-T
CAS :5-MeO-pyr-T (5-Methoxy pyrrolidinyltryptamine) acts as a 5-HT1AR agonist, exhibiting Ki values of 0.577 μM and 373 μM for 5-HT1AR and 5-HT2AR, respectively. It inhibits the reuptake of 5-HT and triggers its release. Additionally, 5-MeO-pyr-T can induce reduced motor activity.Formule :C15H20N2OCouleur et forme :SolidMasse moléculaire :244.33DAA-1106
CAS :DAA-1106 is a potent and selective ligand for PBR, acting as a potent and selective agonist at the peripheral benzodiazepine receptor.Formule :C23H22FNO4Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :395.42TET-13
TET-13 is a positive allosteric modulator of the GABAA receptor with an EC50 of 5.65 μM, which is more potent than Etomidate (EC50: 9.29 μM). It exhibits strong anesthetic effects in both mice and rats, with an ED50 of 0.48 mg/kg in mice and 0.69 mg/kg in rats.Formule :C15H16N2O3SCouleur et forme :SolidMasse moléculaire :304.36Pyrazolam
CAS :Pyrazolam is a psychoactive benzodiazepine compound serving as a central nervous system depressant. [Pyrazolam] can lead to psychomotor impairment.Formule :C16H12BrN5Couleur et forme :SolidMasse moléculaire :354.2AChE-IN-42
Compound AChE-IN-42, also known as Compound 28, is an acetylcholinesterase (AChE) inhibitor with an inhibition constant (K i) of 0.44 μM [1].Couleur et forme :Odour SolidSoclenicant
CAS :Soclenicant is a negative-altering modulator of α 7 -nAChR for anxiety, depression, and PTSD, due to its high selectivity, oral availabilityFormule :C24H26N4O3Degré de pureté :99.57%Couleur et forme :SoildMasse moléculaire :418.49Anisatin
Anisatin is a useful organic compound for research related to life sciences and the catalog number is T124719.Formule :C15H20O8Couleur et forme :SolidMasse moléculaire :328.317β-Amyloid (10-20)
CAS :Amyloid β-Protein (10-20) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Amyloid β protein fragment containing the α-Formule :C71H99N17O16Degré de pureté :98%Couleur et forme :Lyophilized PowderMasse moléculaire :1446.652-(2-(1-Benzylpiperidin-4-yl)ethyl)isoindoline-1,3-dione
CAS :2-(2-(1-Benzylpiperidin-4-yl)ethyl)isoindoline-1,3-dione exhibits acetylcholinesterase inhibitory activity with an IC50 of 0.08 µM.Formule :C22H24N2O2Degré de pureté :99.41%Masse moléculaire :348.44AChE/BChE-IN-13
AChE/BChE-IN-13 (compound 5j) serves as a potent dual inhibitor of both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), exhibiting half-maximalFormule :C21H18N8O7Couleur et forme :SolidMasse moléculaire :494.42Exosome Compound Library
76 exosome-related compounds that can be used for high-throughput and high-content screening.
Couleur et forme :Odour SolidSLAFVDVLN
SLAFVDVLN is a peptide molecule that functions as a BACE-1 inhibitor, exhibiting a Ki value of 94 nM. Additionally, SLAFVDVLN is capable of reducing the production of Aβ42.Formule :C45H72N10O14Couleur et forme :SolidMasse moléculaire :977.11Quetiapine-d4 fumarate
CAS :Deuterium-labeled Quetiapine fumarate; an antidepressant and anxiolytic 5-HT agonist, dopamine antagonist.Formule :C25H29N3O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :503.61β-Secretase Inhibitor I
CAS :β-Secretase Inhibitor I is a highly potent inhibitor of the β-secretase enzyme.Formule :C18H18F3N5O2SCouleur et forme :SolidMasse moléculaire :425.43Orexin A (human, rat, mouse) acetate
Orexin A (human, rat, mouse) acetate (Hypocretin-1 (human, rat, mouse) acetate) is an excitatory neuropeptide with analgesic properties.Formule :C154H247N47O46S4Couleur et forme :SolidMasse moléculaire :3621.15PF-03382792
CAS :PF-03382792 is a small molecule 5-HT4 receptor activator for the study of Alzheimer's disease.Formule :C23H32FN3O4Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :433.52α-Conotoxin AuIB
CAS :Selective antagonist of α3β4 nicotinic acetylcholine receptors.Formule :C65H89N17O21S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1572.76(-)-2-Phenylpropylamine
CAS :(-)-2-Phenylpropylamine ((S)-2-Phenylpropylamine) (compound 3b) functions as an inhibitor for both MAO-A and MAO-B, with Ki values of 584 μM and 156 μM, respectively.Formule :C9H13NCouleur et forme :SolidMasse moléculaire :135.21Vanutide cridificar
CAS :Vanutide cridificar (ACC-001) is an aminoterminal Aβ1-7 peptide conjugate, employed in Alzheimer’s disease (AD) research [1].Couleur et forme :LiquidPotassium Channel Targeted Library
A unique collection of xnum potassium channel blockers and agonists for high throughput and high content screening;Couleur et forme :Odour SolidRef: TM-L7300
1mgÀ demander30μL*10mM (DMSO)À demander50μL*10mM (DMSO)À demander100μL*10mM (DMSO)À demander250μL*10mM (DMSO)À demander4-Hydroxy MPT
CAS :4-Hydroxy MPT (4-OH-MPT) is a serotonin-active compound that acts as an agonist for 5-HT2A and 5-HT2B receptors, with EC50 values of 3.82 nM and 3.4 nM, respectively.Formule :C14H20N2OCouleur et forme :SolidMasse moléculaire :232.32Calmodulin-Dependent Protein Kinase II (281-309)
CAS :Calmodulin-Dependent Protein Kinase II (281-309) is a synthetic peptide that can be phosphorylated at Thr286 by PKC and inhibits CaM kinase II (IC50 = 80 nM).Formule :C146H254N46O39S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3374.06Fezolamine
CAS :Fezolamine: a new, non-tricyclic, oral antidepressant, selectively inhibits norepinephrine uptake over serotonin or dopamine.Formule :C20H23N3Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :305.42BACE1-IN-15
BACE1-IN-15 (Compound 72) is a selective β-secretase 1 (BACE-1) inhibitor with oral bioavailability and blood-brain barrier permeability, exhibiting an IC50 value of 121.65 nM, and an IC50 of 480.92 nM for BACE-2. BACE1-IN-15 is applicable for research in the field of Alzheimer's disease.Couleur et forme :Odour SolidFemoxetine
CAS :Femoxetine: antidepressant, enhances morphine, inhibits MAO-A/B, boosts mice's exercise capacity.Formule :C20H25NO2Degré de pureté :99.1% - 99.35%Couleur et forme :SolidMasse moléculaire :311.421-Ethyl-1H-indole
CAS :1-Ethyl-1H-indole exhibits inhibitory activity against AChE (IC₅₀ = 101 µM) and can be used in related research in the field of life sciences.Formule :C10H11NDegré de pureté :98.80%Couleur et forme :SolidMasse moléculaire :145.2Histamine & Melatonin Receptor-Targeted Compound Library
A unique collection of xnum compounds targeting histaminergic receptor and melatonin receptor for high throughput screening (HTS) and high content screening (HCS
Couleur et forme :Odour Solid5-HT2A receptor agonist-6
CAS :5-HT2A receptor agonist-6 (compound 47) is a selective agonist of the 5-HT2A receptor with a pEC50 value of 6.58.Formule :C18H19N3O3Couleur et forme :SolidMasse moléculaire :325.36Neurotransmitter Receptor Compound Library
A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening；
Couleur et forme :Odour Solidα-Bungarotoxin
CAS :Neurotoxin that blocks neuromuscular transmission via irreversible inhibition of nicotinic ACh receptors (nAChRs).Formule :C338H529N97O105S11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :7984.14rac-Desethyl Oxybutynin (hydrochloride)
CAS :rac-Desethyl oxybutynin, active oxybutynin metabolite, binds to mAChRs; K_i values 3.12-16 nM; lowers rat micturition pressure.Formule :C20H28ClNO3Couleur et forme :SolidMasse moléculaire :365.894-Bromo-2,5-DMMA
CAS :4-Bromo-2,5-DMMA (Compound 2) demonstrates affinity for the 5-HT2 binding site and has an ED50 of 0.82 mg/kg in rat discrimination experiments.Formule :C12H18BrNO2Couleur et forme :SolidMasse moléculaire :288.18AChE-IN-41
AChE-IN-41 (Compound 2), a Galantamine-Memantine hybrid, possesses cholinesterase inhibitory capabilities.Couleur et forme :Odour SolidBChE-IN-19
BChE-IN-19 (Compound 7b), a para-substituted indone derivative, exhibits potent inhibitory activity against butyryl cholinesterase (BChE) with an IC50 value ofFormule :C25H31NO5Couleur et forme :SolidMasse moléculaire :425.52Serotonin Receptor-Targeted Compound Library
A unique collection of xnum compounds targeting serotonin receptors for high throughput screening and high content screening;Couleur et forme :Odour SolidRef: TM-L2800
1mgÀ demander30μL*10mM (DMSO)À demander50μL*10mM (DMSO)À demander100μL*10mM (DMSO)À demander250μL*10mM (DMSO)À demanderPSEM 308 hydrochloride
PSAM agonist targeting PSAML141F-GlyR and related ion channels in mice; ideal concentration ≤5 mg/kg; plasmids at Addgene.Couleur et forme :SolidHeliosupine N-oxide
Heliosupine N-oxide is a useful organic compound for research related to life sciences and the catalog number is T125058.Formule :C20H31NO8Couleur et forme :SolidMasse moléculaire :413.467Inaperisone
CAS :Inaperisone: a novel muscle relaxant that indirectly inhibits voiding reflex via brainstem GABAB receptors.Formule :C16H23NODegré de pureté :98.83%Couleur et forme :SolidMasse moléculaire :245.36Notch 1
CAS :Notch1 (Notchhomolog 1, translocation-associated) encodes a protein that is a member of the NOTCH family. This type I transmembrane protein family is characterized by common structural features, including an extracellular domain made up of multiple epidermal growth factor-like (EGF) repeats and an intracellular domain composed of various types of domains.Formule :C62H97N15O22S3Couleur et forme :SolidMasse moléculaire :1500.725-HT6 inverse agonist 1
CAS :5-HT6 inverse agonist 1 (Compound 33) is an antagonist of the 5-HT6 receptor with a Ki of 23 nM and a Kb of 6.62 nM. This compound can inhibit 5-HT6R-mediated Cdk5 and mTOR signaling pathways and reduce tactile allodynia induced by spinal nerve ligation (SNL) in rat models.Formule :C22H22Cl2FN3O3SCouleur et forme :SolidMasse moléculaire :498.4(+)-Cinchonaminone
CAS :(+)-Cinchonaminone shows monoamine oxidase (MAO) inhibitory activity.Formule :C19H24N2O2Couleur et forme :SolidMasse moléculaire :312.413AAK1-IN-9
AAK1-IN-9 (Compound 3) is an inhibitor of AAK1 (adaptor associated kinase 1) with an IC50 value of 10.92 nM, and it is applicable in the study of neurodegenerative diseases.Couleur et forme :Odour Solid
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