Neuroscience
Les inhibiteurs en neurosciences sont des composés conçus pour moduler l'activité de protéines, d'enzymes ou de récepteurs spécifiques au sein du système nerveux. Ces inhibiteurs sont cruciaux pour étudier les mécanismes moléculaires sous-jacents au fonctionnement neuronal, à la transmission synaptique et aux maladies neurodégénératives. En ciblant les récepteurs des neurotransmetteurs, les canaux ioniques et les voies de signalisation, les inhibiteurs en neurosciences facilitent l'exploration du fonctionnement cérébral et le développement de stratégies thérapeutiques pour des troubles neurologiques tels que la maladie d'Alzheimer, de Parkinson et l'épilepsie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs en neurosciences de haute qualité pour soutenir vos recherches en neurobiologie, neuropharmacologie et sciences cognitives.
Sous-catégories appartenant à la catégorie "Neuroscience"
- récepteur 5-HT(1.025 produits)
- ACK(1 produits)
- AChR(645 produits)
- ATP Citrate Lyase(17 produits)
- Récepteur adrénergique(3.018 produits)
- BACE(37 produits)
- Bêta-amyloïde(228 produits)
- CaMK(73 produits)
- COX(600 produits)
- Récepteur de la dopamine(445 produits)
- Récepteur GABA(372 produits)
- Gamma-sécrétase(61 produits)
- GluR(265 produits)
- GlyT(26 produits)
- Récepteur de l'histamine(385 produits)
- LRRK2(43 produits)
- Récepteur de la mélatonine(26 produits)
- NMDAR(10 produits)
- Récepteur OX(41 produits)
- Récepteur opioïde(327 produits)
Affichez 12 plus de sous-catégories
5530 produits trouvés pour "Neuroscience"
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Brasofensine Maleate
CAS :Brasofensine Maleate inhibits the monoamine re-uptake.Formule :C20H24Cl2N2O5Couleur et forme :SolidMasse moléculaire :443.32BACE-1 inhibitor 1
CAS :BACE-1 inhibitor 1 (Compound 8a) is an effective BACE-1 inhibitor (IC50: 56 nM).Formule :C17H14BrF3N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :443.22VU 0255035
CAS :VU 0255035 is a highly selective, competitive and brain penetrant muscarinic M1 receptor antagonist with an IC50 of 130 nM.
Formule :C18H20N6O3S2Degré de pureté :98.09% - 98.1%Couleur et forme :SolidMasse moléculaire :432.52rTRD01
CAS :rTRD01 is a TDP-43 ligand that selectively binds to the RRM1 and RRM2 domains of TDP-43, exhibiting a dissociation constant (Kd) of 89 µM for TDP-43 102–269.Formule :C18H21FN4O2Degré de pureté :99.44%Couleur et forme :SolidMasse moléculaire :344.38rel-HDMP 28 hydrochloride
CAS :Rel-HDMP-28 hydrochloride (Compound 2g) is an analogue of methylphenidate, exhibiting selective affinity for the serotonin transporter (SERT) with a binding constant (Ki) of 105 nM [1].Formule :C18H22ClNO2Couleur et forme :SolidMasse moléculaire :319.83NO-711ME
CAS :NO-711ME (N-O711 Methyl ester) is a prodrug of NO-711. It also is a potent and selective GABA uptake inhibitor.Formule :C22H24N2O3Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :364.44Ref: TM-T24540
1mg64,00€5mg129,00€10mg188,00€25mg299,00€50mg427,00€100mg575,00€200mg767,00€1mL*10mM (DMSO)138,00€Piperidine-4-sulfonic acid
CAS :Piperidine-4-sulfonic acid is a potent GABA agonist, demonstrating an IC50 value of 0.034 μM for the inhibition of H-GABA binding [1].Formule :C5H11NO3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :165.21MAO-B-IN-19
CAS :MAO-B-IN-19, a selective MAO-B inhibitor, exhibits neuroprotective and anti-inflammatory properties and demonstrates an IC50 value of 0.67 μM [1].Formule :C15H11FO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :242.25Cyclophostin
CAS :Cyclophostin is an irreversible inhibitor of acetylcholinesterase (AChE).Formule :C8H11O6PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :234.14Facinicline hydrochloride
CAS :Facinicline hydrochloride (RG3487) is both a novel nicotinic alpha-7 receptor (alpha7nAChR) partial agonist (Ki = 6 nM) and an antagonist of 5-HT3(Ki = 1.2 nM).Formule :C15H19ClN4ODegré de pureté :98.70%Couleur et forme :SolidMasse moléculaire :306.79Zamifenacin fumarate
CAS :Zamifenacin fumarate (UK-76654 fumarate) is a potent and gut-selective antagonist of muscarinic M3 receptor.Formule :C31H33NO7Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :531.6Ref: TM-T13385
2mg34,00€5mg50,00€10mg75,00€25mg128,00€50mg200,00€100mg304,00€200mg424,00€1mL*10mM (DMSO)58,00€Biphenylindanone A
CAS :Biphenylindanone A is a selective potentiator of human mGluR2 (hmGluR2),and for the treatment of neurological disorders.Formule :C30H30O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :454.565-HT3 antagonist 1
CAS :5-HT3 antagonist 1 is a potent and selective antagonist of 5-HT3 receptor.Formule :C22H27N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :377.48CGP 54626 hydrochloride
CAS :CGP 54626 hydrochloride is a GABAB receptor antagonist.Formule :C18H29Cl3NO3PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :444.76BACE1-IN-13
CAS :BACE1-IN-13 (Compound 36), an orally active inhibitor of BACE1, exhibits high potency with an IC50 of 2.9 nM and demonstrates greater efficacy in hAβ42 cells (Formule :C20H17FN8O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :420.4GR 125487 sulfamate
CAS :GR 125487 sulfamate is a 5-HT4 receptor antagonist.Formule :C19H29FN4O8S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :524.58Octahydroaminoacridine succinate
CAS :Octahydroaminoacridine succinate, an acetylcholinesterase inhibitor, is used potentially for the treatment of Alzheimer's disease.Formule :C17H24N2O4Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :320.38AAK1-IN-4
CAS :AAK1-IN-4 selectively inhibits AAK1 with IC50 of 4.6 nM; penetrates CNS, oral bioactive, potential for studying neuropathic pain.Formule :C20H28N4O3Couleur et forme :SolidMasse moléculaire :372.46(1α,1'S,4β)-Lanabecestat
CAS :(1α,1'S,4β)-Lanabecestat is a Beta site APP Cleaving Enzymel (BACE1) inhibitor, and has IC50s of 2.2 nM (TR-FRET assay) and 0.28 nM (sAPPp release assay),Formule :C26H28N4OCouleur et forme :SolidMasse moléculaire :412.53β-Secretase Inhibitor IV
CAS :β-Secretase Inhibitor IV is a potent, cell-active inhibitor of BACE-1(IC50s of 15.6 and 16.3nM under BACE-1 concentrations of 2 nM and 100 pM, respectively).Formule :C31H38N4O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :578.72Adipiplon
CAS :Adipiplon(NG2-73, NG273) is a novel selective gamma-aminobutyric acid (GABA) partial agonist.Formule :C18H18FN7Couleur et forme :SolidMasse moléculaire :351.38NAS-181 free base
CAS :NAS-181 free base is a 5-HT(1B) receptor antagonist.Formule :C19H26N2O4Couleur et forme :SolidMasse moléculaire :346.42NCS-382 sodium
CAS :NCS-382 (sodium) is a potent antagonist of the GABA receptor, exhibiting anti-sedative and anti-hypnotic properties, with applications in neurological diseaseFormule :C13H13NaO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :240.23(2R,4R)-APDC
CAS :(2R,4R)-APDC is a selective group II metabotropic glutamate receptors (mGluRs) agonist. It has anticonvulsant and neuroprotective effects.Formule :C6H10N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :174.15DU-125530
CAS :DU-125530 is a 5-HT1A receptor antagonist.Formule :C23H26ClN3O5SCouleur et forme :SolidMasse moléculaire :491.99BMS-932481
CAS :BMS-932481 is a γ-secretase modulator.Formule :C24H24FN7OCouleur et forme :SolidMasse moléculaire :445.49CP-122288
CAS :CP-122288: potent, selective 5-HT1B/D/F agonist; inhibits plasma protein extravasation, neurogenic inflammation.Formule :C16H23N3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :321.44Anti-amyloid agent-1
CAS :Anti-amyloid agent-1 is a potent compound that inhibits amyloid aggregation, offering a promising approach for research into the treatment of amyloidosis [1].Formule :C21H17F3N2O3Couleur et forme :SolidMasse moléculaire :402.37QM-FN-SO3
CAS :QM-FN-SO3 is a blood-brain barrier (BBB)-penetrable, near-infrared (NIR) probe with aggregation-induced emission (AIE) activity, specifically designed for the detection of Aβ plaques. It exhibits ultra-high signal-to-noise (S/N) ratio, binding affinity, and high-performance NIR emission, making it suitable for in vivo detection of Aβ plaques [1].Formule :C29H25N4NaO3S2Couleur et forme :SolidMasse moléculaire :564.65(±)-Fabesetron hydrochloride
CAS :FK1052 hydrochloride is a potent 5-HT3 and 5-HT4 receptor dual antagonist.Formule :C18H20ClN3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :329.82Tolterodine Dimer
CAS :Tolterodine Dimer is a derivative of Tolterodine -- a muscarinic receptor antagonist that is used to treat patients with overactive bladder.Formule :C35H41NO2Couleur et forme :SolidMasse moléculaire :507.71CGP 55845 hydrochloride
CAS :CGP55845 hydrochloride is a potent and selective GABAB receptor antagonist with an IC 50 of 6 nM which can be used in neurological research [1] [2].Formule :C18H23Cl3NO3PCouleur et forme :SolidMasse moléculaire :438.71PNU109291
CAS :PNU109291, a potent and selective agonist of the 5-HT1D receptor, effectively mitigates dural plasma extravasation induced by trigeminal ganglion stimulation.Formule :C24H31N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :409.52CGP36216 hydrochloride
CAS :CGP36216 hydrochloride acts as a selective antagonist at the presynaptic GABA receptor, specifically binding to the GABAB receptor with a Ki value of 0.3 μM. This compound is leveraged in research focused on anxiety and trauma-related disorders [1] [2].Formule :C5H15ClNO2PCouleur et forme :SolidMasse moléculaire :187.6Befiradol
CAS :Befiradol (NLX-112) is an agonist of 5-HT1A receptor.Formule :C20H22ClF2N3OCouleur et forme :SolidMasse moléculaire :393.86Gentisein
CAS :Gentisein (NSC-329491), a primary metabolite of Mangiferin, exhibits significant inhibition of serotonin uptake, demonstrating potency with an IC50 value of 4.7Formule :C13H8O5Degré de pureté :96.89%Couleur et forme :SolidMasse moléculaire :244.2LY108742
CAS :LY108742 is an antagonist of 5-HT2.Formule :C21H28N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :356.46Yhhu-3792 hydrochloride
CAS :Yhhu-3792 hydrochloride is a compound that bolsters the self-renewal capacity of neural stem cells (NSCs), catalyzes the Notch signaling pathway, and upregulates expression of Hes3 and Hes5. It augments the NSC pool, stimulates endogenous neurogenesis in the mouse hippocampal dentate gyrus (DG), and enhances mice's spatial and episodic memory skills. This compound shows promise for researching learning and memory impairments linked to DG dysfunction [1].Formule :C24H25ClN4O2Couleur et forme :SolidMasse moléculaire :436.93BChE-IN-20
CAS :BChE-IN-20 (compound 7c) is a potent, selective inhibitor of BChE, demonstrating IC50 values of 105 nM for eqBChE and 2.3 nM for hBChE.Formule :C27H39N5O2Couleur et forme :SolidMasse moléculaire :465.63QR-0217
CAS :QR-0217 is a potent inhibitor of both Aβ1-40 and α-synuclein aggregation, exhibiting an IC50 of 7.5 µM for Aβ1-40.Formule :C19H13NO3Couleur et forme :SolidMasse moléculaire :303.31SCS
CAS :SCS is a GABAA receptor antagonist.Formule :C14H12N2O3Degré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :256.26MGS-0039
CAS :MGS-0039: Group II mGluR2/3 antagonist, non-serotonergic antidepressant-like effect, AMPA involvement, regulates dopamine in NAc.Formule :C15H14Cl2FNO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :378.18mGluR5 antagonist-1
CAS :mGluR5 antagonist-1 (compound 10) is a potent mGluR5 inhibitor exhibiting an IC50 of 11.5 nM and demonstrates antidepressant effects [1].Formule :C23H18N4O2Couleur et forme :SolidMasse moléculaire :382.41U 89843A
CAS :U 89843A is a positive allosteric modulator of gamma-aminobutyric acid (GABA)A receptors.Formule :C16H23N5Degré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :285.39BMT-124110
CAS :BMT-124110: AAK1 inhibitor, IC50=0.9 nM, pain relief. BMT-090605: BIKE inhibitor, IC50=17 nM; GAK inhibitor, IC50=99 nM.Formule :C21H27N3O3Degré de pureté :98.07%Couleur et forme :SolidMasse moléculaire :369.463-Bromocytisine
CAS :3-Bromocytisine ((-)-3-Bromocytisine) is an effective agonist of nAChR (IC50s: 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7).Formule :C11H13BrN2ODegré de pureté :99.974%Couleur et forme :SolidMasse moléculaire :269.14Ref: TM-T10108
1mg95,00€5mg202,00€10mg293,00€25mg494,00€50mg710,00€100mg973,00€200mg1.305,00€1mL*10mM (DMSO)178,00€(+)-Bicuculline methiodide
CAS :(+)-Bicuculline methiodide is a GABAA receptor blocker that blocks epileptogens and may be used in the study of neurological disorders.Formule :C21H20INO6Degré de pureté :99.24%Couleur et forme :SolidMasse moléculaire :509.29LY3202626
CAS :LY3202626, an amyloid precursor protein secretase (BACE protein) inhibitor, is used for the treatment of Alzheimer's disease.Formule :C22H20F2N8O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :498.51PZ-1190
CAS :PZ-1190, a multitarget ligand for serotonin and dopamine receptors, exhibits potential antipsychotic activity in rodents [1].Formule :C27H30N4O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :506.68FGIN-1-27
CAS :FGIN-1-27 is a high-affinity agonist of the translocator protein and a specific peripheral benzodiazepine receptor (PBR) ligand(Ki = 5.0 nM).Formule :C28H37FN2ODegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :436.62-Methyl-5-HT
CAS :2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.Formule :C11H14N2ODegré de pureté :97.18%Couleur et forme :SolidMasse moléculaire :190.24Ref: TM-T10075
5mg48,00€10mg84,00€25mg177,00€50mg334,00€100mg500,00€500mg1.099,00€1mL*10mM (DMSO)50,00€(R)-4-Amino-3-hydroxybutyric Acid
CAS :(R)-4-Amino-3-hydroxybutyric acid, also known as (R)-GABOB, acts as a modulator of GABA receptors, specifically binding to both GABAA and GABAB receptors and blocking GABA reuptake in rat brain synaptosomes. Additionally, it serves as a GABAC receptor agonist, triggering currents in patch-clamp assays with Xenopus oocytes that express the human receptor. In vivo studies reveal its capability to suppress electrical discharges in the amygdala in cats undergoing N-amidinobenzamide-triggered seizures, indicating its potential therapeutic application in managing seizure disorders.Formule :C4H9NO3Couleur et forme :SolidMasse moléculaire :119.12Abaperidone
CAS :Abaperidone is an atypical antipsychotic, antagonizes 5-HT2A (IC50=6.2 nM) and D2 receptors (IC50=17 nM), reduces hsp70 mRNA in rat brains.Formule :C25H25FN2O5Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :452.47SDZ-216525
CAS :SDZ-216525, a 5-HT1A receptor antagonist, inhibits the tracheal contractions induced both by NKA (10 nM-3 microM) and 5-HT (10 nM-10 microM) (n=4-10).Formule :C25H28N4O5SCouleur et forme :SolidMasse moléculaire :496.58BMS-933043
CAS :BMS-933043: α7 nAChR partial agonist, binds rat (Ki=3.3 nM) & human (Ki=8.1 nM), agonist with EC50=23.4 nM (calcium assay), 0.14-0.29 μM (electrophysiology).Formule :C16H19N7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :325.37Velusetrag
CAS :Velusetrag(TD-5108), a potent 5-HT4 agonist, is in development for gastroparesis, constipation, and IBS.Formule :C25H36N4O5SCouleur et forme :SolidMasse moléculaire :504.64MDL-74156
CAS :MDL-74156 is an active metabolite of dolasetron and a 5-hydroxy-tryptamine3 (5-HT3) antagonist.Formule :C19H22N2O3Couleur et forme :SolidMasse moléculaire :326.39MTPG
CAS :Group II/group III metabotropic glutamate receptor antagonistFormule :C10H11N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :233.23CGP 64213
CAS :CGP 64213 is a GABAb receptor agonist.Formule :C26H36IN2O7PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :646.45Tematropium
CAS :Tematropium (CDDD3602) possesses anticholinergic effects and can be used in neurological studies.Formule :C21H31NO8SDegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :457.54Ref: TM-T10732
1mg147,00€5mg356,00€10mg558,00€25mg880,00€50mg1.179,00€100mg1.603,00€200mg2.152,00€1mL*10mM (DMSO)413,00€Philanthotoxin 74 dihydrochloride
CAS :Philanthotoxin 74 dihydrochloride is an antagonist of AMPAR with IC50s of 263 and 296 nM for GluR3 and GluR1.Formule :C24H44Cl2N4O3Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :507.54Osemozotan HCl
CAS :Osemozotan is a 5-HT1A receptor agonist potentially for the treatment of generalized anxiety disorder.Formule :C19H22ClNO5Degré de pureté :98.87% - 99.63%Couleur et forme :SolidMasse moléculaire :379.84Atabecestat
CAS :Atabecestat (JNJ-54861911) is an oral BACE1 inhibitor for Alzheimer's treatment with strong brain uptake and lasting PK/PD effects.Formule :C18H14FN5OSDegré de pureté :99.21% - 99.77%Couleur et forme :SolidMasse moléculaire :367.4Ref: TM-T14338
1mg123,00€5mg295,00€10mg477,00€25mg954,00€50mg1.279,00€100mg1.728,00€1mL*10mM (DMSO)326,00€WAY-607695
CAS :WAY-607695 is a potential 5-HT1A receptor agonist.Formule :C13H12FNO2Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :233.24BuChE-IN-TM-10
CAS :TM-10: Potent BuChE inhibitor, IC50 8.9 nM, disaggregates Aβ, antioxidant, BBB penetrant, may treat Alzheimer's.Formule :C32H38N2O3Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :498.66R-(+)-EU-1180-453
CAS :R-(+)-EU-1180-453 is a novel GluN2C/D selective NMDAR-positive modulator for the study of neurological disorders.Formule :C22H21FN2O3Degré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :380.41VU6004909
CAS :VU6004909 is an mGlu5 receptor orthosteric modulator that reverses MK801-induced increased cortical activity and cognitive dysfunction.Formule :C21H15FN2O4Degré de pureté :96.68% - 98.44%Couleur et forme :SolidMasse moléculaire :378.35SB 216641 hydrochloride
CAS :SB 216641 hydrochloride (SB-216641A) is a 5-HT1B/D receptor antagonist with anxiolytic properties.Formule :C28H31ClN4O4Degré de pureté :98.06% - 99.23%Couleur et forme :SolidMasse moléculaire :523.02γ-Secretase-IN-1
CAS :γ-Secretase-IN-1 is a γ-secretase inhibitor that displays partial antiproliferative activity against T-47D cells.Formule :C27H24F2N4O3Degré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :490.5Ref: TM-T3521
1mg120,00€5mg385,00€10mg618,00€25mg1.224,00€50mg1.648,00€100mg2.232,00€1mL*10mM (DMSO)416,00€AMPA receptor antagonist-3
CAS :AMPA receptor antagonist-3 is an AMPA receptor antagonist.Formule :C20H19N5O2SDegré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :393.46Ref: TM-T61813
1mg185,00€5mg425,00€10mg625,00€25mg938,00€50mg1.311,00€100mg1.795,00€1mL*10mM (DMSO)455,00€AMPA receptor modulator-1
CAS :AMPA receptor modulator-1 can be activated by glutamate, thereby modulating ion channels.
Formule :C16H11ClF3NO2Degré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :341.71TZ3O
CAS :TZ3O is an anticholinergic compound with neuroprotective activity.TZ3O ameliorates memory impairment in Scopolamine-induced Alzheimer's type model in rats.Formule :C18H13NO4SDegré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :339.37Didesmethyl cariprazine
CAS :Didesmethyl cariprazine, Cariprazine's active metabolite, treats schizophrenia/bipolar with D3/D2 affinity; half-life 1-3 weeks.Formule :C19H28Cl2N4ODegré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :399.36PXS-5153A
CAS :PXS-5153A rapidly inhibits lysyl oxidase 2/3 enzymes, blocks activity in 15 mins, and reduces fibrosis.Formule :C20H25Cl2FN4O2SDegré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :475.41PXS-5120A
CAS :PXS-5120A is an irreversible fluoroallylamine Lysyl Oxidase-like 2/3 (LOXL2/3) inhibitor with anti-fibrotic activity.Formule :C22H25ClFN3O4SDegré de pureté :97.02%Couleur et forme :SolidMasse moléculaire :481.97Ref: TM-T12584
1mg205,00€2mg293,00€5mg462,00€10mg612,00€25mg893,00€50mg1.224,00€100mg1.639,00€1mL*10mM (DMSO)502,00€Lumateperone
CAS :Lumateperone (ITI 722) is a 5HT2A receptor antagonist and a dopamine receptor phosphoprotein modulator (DPPM).Formule :C24H28FN3ODegré de pureté :99.68% - 99.91%Couleur et forme :SolidMasse moléculaire :393.5SB-616234-A
CAS :SB-616234-A is a selective and orally bioavailable antagonist of 5-HT1B receptor, with anxiolytic and antidepressant activity.Formule :C32H36ClN5O3Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :574.11MDR-1339
CAS :MDR-1339 is a blood-brain-barrier-permeable inhibitor of amyloid-β (Aβ) aggregation.Formule :C20H22O4Degré de pureté :98.57%Couleur et forme :SolidMasse moléculaire :326.39BMS-986176
CAS :AAK1-IN-1 is a highly selective and potent inhibitor of adaptor associated kinase 1 (AAK1, IC50 = 2 nM).
Formule :C19H23F4N3ODegré de pureté :98.58% - 98.7%Couleur et forme :SolidMasse moléculaire :385.4CGS-9895
CAS :CGS-9895 is a GABA antagonist that operates by interacting with the benzodiazepine binding site on GABA receptors containing the γ subunit (ag).Formule :C17H13N3O2Couleur et forme :SolidMasse moléculaire :291.304TP003
CAS :TP003 is a novel non-selective GABAA receptor benzodiazepine site agonist with affinity for α1β2gam2, α2β3gam2, α3β3gam2, α5β2gam2, EC50 of 20.3, 10.6, 3.24, 5.
Formule :C23H16F3N3ODegré de pureté :99.17%Couleur et forme :SolidMasse moléculaire :407.39Amyloid-β-IN-3
CAS :Amyloid-β-IN-3 (EX.113) is a selective inhibitor of γ-secretase. It demonstrates inhibitory activity on Aβ42 secretion in H4 cells, with an EC50 value of 148 nM. By modulating the catalytic activity of γ-secretase, Amyloid-β-IN-3 decreases Aβ42 production, thereby alleviating neurotoxicity caused by Aβ deposition. It holds potential for Alzheimer's disease (AD) research.Formule :C22H21F2N3O2Couleur et forme :SolidMasse moléculaire :397.42SRI-31255
CAS :SRI-31255 is an orally active LRRK2 inhibitor, with IC50 values of 520 nM for human wild-type (WT) and 427 nM for the G2019S mutant. It inhibits kinase activity by binding to the ATP-binding pocket of LRRK2, providing neuroprotective effects. SRI-31255 serves as a lead compound for developing LRRK2-targeted therapies for Parkinson’s disease research.Formule :C15H14N4Couleur et forme :SolidMasse moléculaire :250.30ASP-2205
CAS :ASP-2205, a 5-HT2C receptor agonist (human 5-HT2C receptor, EC50=0.85 nM; rat 5-HT2C receptor, EC50=2.5 nM), enhances the urethral closure reflex mediated by the genital nerve, thereby preventing urinary incontinence.Formule :C19H28N2OCouleur et forme :SolidMasse moléculaire :300.441,9-Dideoxyforskolin
CAS :The compound is an inactive analog of forskolin(an adenylyl cyclase activator).Formule :C22H34O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :378.5Antioxidant agent-8
Antioxidant agent-8, an oral Aβ 1-42 inhibitor, reduces fibril aggregation & promotes disaggregation; it's neuroprotective & BBB permeable.Formule :C13H12O5Couleur et forme :SolidMasse moléculaire :248.23EF1502 free base
CAS :EF1502 is a potent and selective GABA transporter inhibitor.Formule :C22H26N2O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :414.58Beloxepin
CAS :Beloxepin is an oral dual selective inhibitor of serotonin and norepinephrine uptake.Formule :C19H21NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :295.38BGT1-IN-1
CAS :BGT1-IN-1 (compound 9) is an effective inhibitor of BGT1, demonstrating IC50 values of 13.9 µM for hBGT1 and 58.3 µM for GAT3. It exhibits no cytotoxic effects and possesses neuroprotective activity.Formule :C6H9NO2Couleur et forme :SolidMasse moléculaire :127.14Nedemelteon
CAS :Nedemelteon is an agonist of the melatonin receptor (melatonin receptor).Formule :C15H18N2O2Couleur et forme :SolidMasse moléculaire :258.32Jimscaline
CAS :Jimscaline (compound R-(-)2) is a 5-HT2A agonist and a mescaline analogue, used in neuroscience research.Formule :C13H19NO3Couleur et forme :SolidMasse moléculaire :237.295ChE/Aβ1-42-IN-1
ChE/Aβ1-42-IN-1 (compound 28) is a potent aggregation inhibitor of ChE and Aβ 1-42 with excellent BBB permeability.Formule :C19H24N2O3Couleur et forme :SolidMasse moléculaire :328.41Befiradol hydrochloride
CAS :Befiradol HCl (NLX-112) is a selective 5-HT1A receptor agonist with anxiolytic effects and prevents ATXN3 aggregation.Formule :C20H23Cl2F2N3ODegré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :430.32OX2R agonist 1
CAS :OX2R agonist 1 is an OX2R activator with an EC50 of less than 100 nM. It is utilized in research related to narcolepsy and cataplexy.Formule :C21H28F2N2O5SCouleur et forme :SolidMasse moléculaire :458.52Tiprenolol hydrochloride
CAS :Tiprenolol hydrochloride is a β-adrenoceptor (β-adrenoceptor) antagonist. This compound is effective in eliminating ventricular arrhythmias in dogs caused by intravenous administration of adrenaline, following inhalation of halothane.Formule :C13H22ClNO2SCouleur et forme :SolidMasse moléculaire :291.84ZK 93426 hydrochloride
CAS :benzodiazepine receptor antagonist,competitiveFormule :C18H21ClN2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :348.82nAChR antagonist 1
CAS :Compound B15, a potent α7 nAChR antagonist, IC50 = 3.3 μM, promising for research on schizophrenia, Alzheimer's, and inflammation.Formule :C19H22N4O2Couleur et forme :SolidMasse moléculaire :338.4Tebideutorexant
CAS :Tebideutorexant, an orexin-1 receptor antagonist, shows anti-panic effects in rodents and humans, providing a tool for stress response and psychiatric research.Formule :C23H16D2F4N4O2Degré de pureté :98.89%Couleur et forme :SolidMasse moléculaire :460.42LY3020371 hydrochloride
CAS :LY3020371 HCl: potent mGlu2/3 antagonist, antidepressant-like; Ki: 5.3/2.5 nM, IC50: 16.2 nM for cAMP inhibition.Formule :C15H16ClF2NO5SCouleur et forme :SolidMasse moléculaire :395.81AChE-IN-24
AChE-IN-24: Strong AChE blocker, crosses blood-brain barrier, IC50=0.053 μM, useful for AD research.Formule :C22H30N2O4S2Couleur et forme :SolidMasse moléculaire :450.61
