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Neuroscience

Neuroscience

Les inhibiteurs en neurosciences sont des composés conçus pour moduler l'activité de protéines, d'enzymes ou de récepteurs spécifiques au sein du système nerveux. Ces inhibiteurs sont cruciaux pour étudier les mécanismes moléculaires sous-jacents au fonctionnement neuronal, à la transmission synaptique et aux maladies neurodégénératives. En ciblant les récepteurs des neurotransmetteurs, les canaux ioniques et les voies de signalisation, les inhibiteurs en neurosciences facilitent l'exploration du fonctionnement cérébral et le développement de stratégies thérapeutiques pour des troubles neurologiques tels que la maladie d'Alzheimer, de Parkinson et l'épilepsie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs en neurosciences de haute qualité pour soutenir vos recherches en neurobiologie, neuropharmacologie et sciences cognitives.

Sous-catégories appartenant à la catégorie "Neuroscience"

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5398 produits trouvés pour "Neuroscience"

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  • BChE-IN-2


    <p>BChE-IN-2, a pyrimidine/pyridine derivative, potently inhibits BChE (Ki 0.099 μM) and shows promise in AD research.</p>
    Formule :C22H31N5
    Couleur et forme :Solid
    Masse moléculaire :365.52
  • CEase-IN-1


    <p>CEase-IN-1 (A1H3), potent CEase inhibitor, IC50 0.36μM, for hypercholesterolemia study.</p>
    Formule :C13H15F3N2O2
    Couleur et forme :Solid
    Masse moléculaire :288.27
  • AAZ-A 154

    CAS :
    <p>AAZ-A 154 is a selective, competitive, and non-hallucinogenic antagonist of the 5-HT2AR. It promotes neuronal growth in rodents and results in lasting beneficial behavioral effects.</p>
    Formule :C14H20N2O
    Couleur et forme :Solid
    Masse moléculaire :232.32
  • (RS)-AMPA hydrochloride

    CAS :
    <p>(RS)-AMPA ((±)-AMPA) hydrochloride is a glutamate analog and serves as an efficient selective agonist for the excitatory neurotransmitter L-glutamic acid (L-glutamic acid). It does not interfere with the binding sites of alginate or NMDA receptors.</p>
    Formule :C7H11ClN2O4
    Couleur et forme :Solid
    Masse moléculaire :222.63
  • LRRK2-IN-6


    <p>LRRK2-IN-6 is an oral, selective LRRK2 inhibitor crossing the blood-brain barrier, targeting GS (IC50: 4.6μM) and WT LRRK2 (IC50: 49μM).</p>
    Formule :C23H24F2N4O2S
    Couleur et forme :Solid
    Masse moléculaire :458.52
  • (9R)-RO7185876

    CAS :
    <p>(9R)-RO7185876 (Compound example 16) is a γ-secretase inhibitor. It reduces the secretion of Αβ42. This compound can be employed in the research of Alzheimer's disease, cerebral amyloid angiopathy, hereditary cerebral hemorrhage with amyloidosis, multi-infarct dementia, senile dementia, or Down syndrome.</p>
    Formule :C25H28F3N7
    Couleur et forme :Solid
    Masse moléculaire :483.532
  • BPN-15606 besylate


    <p>BPN-15606 besylate is a potent oral γ-secretase regulator reducing Aβ42 and Aβ40 with good pharmacokinetics. IC50: 7 nM (Aβ42), 17 nM (Aβ40).</p>
    Formule :C29H29FN6O4S
    Couleur et forme :Solid
    Masse moléculaire :576.64
  • DSP-1053 benzenesulfonate

    CAS :
    <p>DSP-1053: Benzylpiperidine-based, potent SERT inhibitor (Ki=1.02nM), partial 5-HT1A receptor agonist (Ki=5.05nM), antidepressant.</p>
    Formule :C32H38BrNO7S
    Couleur et forme :Solid
    Masse moléculaire :660.62
  • FCOB02

    CAS :
    <p>FCOB02 is a monoamine oxidase B (MAO-B) ligand. It can be labeled as [18F]FCOB02, serving as a 4-methylcoumarin-like targeting probe. [18F]FCOB02 demonstrates high affinity for MAO-B, with an IC50 of 10.68 nM. It is utilized for specific imaging and quantitative analysis of MAO-B in vivo.</p>
    Formule :C16H12FNO3
    Couleur et forme :Solid
    Masse moléculaire :285.27
  • Rocavorexant

    CAS :
    <p>Rocavorexant is an antagonist of the orexin-1 receptor (orexin-1 receptor), exhibiting a pIC50 value of 9.1 for human OX1 and a pIC50 of 6.0 for human OX2.</p>
    Formule :C18H19F3N8O
    Couleur et forme :Solid
    Masse moléculaire :420.392
  • VU6005806

    CAS :
    <p>VU6005806 is a potent M4 PAM with EC50s: 94 nM (human), 28 nM (rat), 87 nM (dog), 68 nM (cyno); studied for neuropsychiatric disorders.</p>
    Formule :C17H16F3N7O2S
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :439.41
  • BACE1-IN-2

    CAS :
    <p>BACE1-IN-2 is a BACE1 inhibitor (IC50: 22 nM).</p>
    Formule :C19H15F4N5O2
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :421.35
  • AAZ-A 154 mesylate

    CAS :
    <p>AAZ-A 154 mesylate mesylate is a selective, competitive, and non-hallucinogenic antagonist of 5-HT2AR. It enhances neuronal growth in rodents and produces enduring beneficial behavioral effects.</p>
    Formule :C15H24N2O4S
    Couleur et forme :Solid
    Masse moléculaire :328.43
  • AAZ-A 154 hydrochloride

    CAS :
    <p>AAZ-A 154 hydrochloride is a selective, competitive, non-hallucinogenic antagonist of 5-HT2AR. It promotes neuronal growth in rodents and results in enduring beneficial behavioral effects.</p>
    Formule :C14H21ClN2O
    Couleur et forme :Solid
    Masse moléculaire :268.78
  • AAZ-A 154 benzoate

    CAS :
    <p>AAZ-A 154 benzoate is a selective, competitive, and non-hallucinogenic 5-HT2AR antagonist. This compound facilitates neuronal growth in rodents and produces lasting beneficial behavioral effects.</p>
    Formule :C21H26N2O3
    Couleur et forme :Solid
    Masse moléculaire :354.44
  • AAZ-A 154 hydrobromide

    CAS :
    <p>AAZ-A 154 hydrobromide is a selective, competitive, non-hallucinogenic 5-HT2AR antagonist. It promotes neuronal growth in rodents and yields enduring beneficial behavioral effects.</p>
    Formule :C14H21BrN2O
    Couleur et forme :Solid
    Masse moléculaire :313.23
  • LOXL2-IN-1 tosylate


    <p>LOX-IN-5 tosylate (compound 22) is a selective oral inhibitor of lysyl oxidase-like 2 (LOXL2) with an IC50 of less than 300 nM, and it exhibits anti-fibrotic properties.</p>
    Formule :C28H33FN4O5S2
    Couleur et forme :Solid
    Masse moléculaire :588.714
  • LY367385 hydrochloride

    CAS :
    <p>LY367385 hydrochloride: selective mGluR1a antagonist, IC50 = 8.8 μM, neuroprotective, anticonvulsant, antiepileptic.</p>
    Formule :C10H12ClNO4
    Couleur et forme :Solid
    Masse moléculaire :245.66
  • CPPG

    CAS :
    <p>CPPG: potent group II/III mGlu receptor antagonist, 20x more selective for group III (IC50: 2.2 nM) than II (46.2 nM) in rat cortex.</p>
    Formule :C11H14NO5P
    Couleur et forme :Solid
    Masse moléculaire :271.21
  • HDAC6-IN-9

    CAS :
    <p>HDAC6-IN-9 is a γ-secretase modulator that can significantly reduce the level of Aβ42 in mouse brain and can be used to study neurological diseases.</p>
    Formule :C19H16N2O3
    Degré de pureté :98.84%
    Couleur et forme :Solid
    Masse moléculaire :320.34
  • MAO-A inhibitor 3

    CAS :
    <p>MAO-A inhibitor3 (Compound 360) is an MAO-A inhibitor with an IC50 greater than 100 μM. It is utilized in the investigation of neurological disorders.</p>
    Formule :C11H8O5
    Couleur et forme :Solid
    Masse moléculaire :220.178
  • Pomaglumetad methionil

    CAS :
    <p>Pomaglumetad methionil is an oral methionine prodrug of the potent specific agonist of mGlu2/3 receptor LY404039.</p>
    Formule :C12H20N2O8S2
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :384.43
  • AChE/BChE/MAO-B-IN-5

    CAS :
    <p>AChE/BChE/MAO-B-IN-5 is a multi-target inhibitor capable of crossing the blood-brain barrier, targeting cholinesterases (AChE and BChE) and monoamine oxidase MAO-B. It exhibits IC50 values of 0.24 µM for AChE, 6.29 µM for BChE, and 0.11 µM for MAO-B. AChE/BChE/MAO-B-IN-5 holds potential for research in neurodegenerative diseases such as Alzheimer's disease.</p>
    Formule :C22H14F3NO2
    Couleur et forme :Solid
    Masse moléculaire :381.347
  • AChE/BChE-IN-3 hydrochloride


    <p>AChE/BChE-IN-3 (BMC-1) HCl is a dual inhibitor with IC50s: eqBChE 0.383 μM, elAChE 6.08 μM.</p>
    Formule :C15H25ClN2O3
    Couleur et forme :Solid
    Masse moléculaire :316.82
  • AChE/BChE-IN-1


    <p>AChE/BChE-IN-1: dual AChE/BChE inhibitor, IC50 of 1.06 nM/7.3 nM, crosses blood-brain barrier, with antioxidant properties for Alzheimer's research.</p>
    Formule :C32H35ClN6O3
    Couleur et forme :Solid
    Masse moléculaire :587.11
  • SB 224289

    CAS :
    <p>SB 224289: selective 5-HT1B antagonist, pKi 8.2, 60x selectivity, effective orally.</p>
    Formule :C32H32N4O3
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :520.62
  • PXS-5153A monohydrochloride

    CAS :
    <p>PXS-5153A is an oral, fast-acting LOXL2/3 inhibitor with IC50 &lt;40 nM for LOXL2 and 63 nM for LOXL3, potentially treating fibrosis.</p>
    Formule :C20H25Cl2FN4O2S
    Degré de pureté :98%
    Couleur et forme :Odour Solid
    Masse moléculaire :475.41
  • Gabaculine HCl

    CAS :
    <p>Gabaculine, an irreversible GABA-T inhibitor (Ki: 2.9 μM), impacts plastid development and affects DPOR/GluTR levels.</p>
    Formule :C7H10ClNO2
    Couleur et forme :Solid
    Masse moléculaire :175.61
  • LRRK2-IN-5


    <p>LRRK2-IN-5 is an oral, BBB-penetrating selective inhibitor for LRRK2 with IC50s: 1.2μM (GS) and 16μM (WT); halts LRRK2 autophosphorylation.</p>
    Formule :C24H26F2N4O2S
    Couleur et forme :Solid
    Masse moléculaire :472.55
  • Aβ-IN-2


    <p>Aβ-IN-2 is a peptide inhibitor of Aβ1-42.</p>
    Formule :C37H51NO
    Couleur et forme :Solid
    Masse moléculaire :525.81
  • hAChE-IN-10

    CAS :
    <p>hAChE-IN-10 (Compound ET11) is an inhibitor of human acetylcholinesterase (AChE) with an IC50 of 6.34 nM. This compound is capable of scavenging free radicals and exhibits antioxidant activity. Additionally, hAChE-IN-10 demonstrates metal-chelating properties, inhibiting Cu2+-induced Aβ1-42 aggregation, reducing amyloid plaque formation, and offering neuroprotective effects. It also ameliorates cognitive impairment in mice induced by Scopolamine.</p>
    Formule :C25H24ClFN6O2
    Couleur et forme :Solid
    Masse moléculaire :494.948
  • SGE-516

    CAS :
    <p>SGE516: neuroactive steroid, enhances GABAA, lowers neuronal activity, protects from seizures.</p>
    Formule :C23H35N3O2
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :385.54
  • LRRK2-IN-4

    CAS :
    <p>LRRK2-IN-4: Potent, selective LRRK2 inhibitor, oral, BBB-penetrating, IC50=2.6 nM, potential for Parkinson's.</p>
    Formule :C25H29ClF2N6O2
    Couleur et forme :Solid
    Masse moléculaire :518.99
  • Ro4368554

    CAS :
    <p>Ro4368554 is a selective 5-HT6 antagonist capable of crossing the blood-brain barrier. It can reverse memory deficits caused by scopolamine and tryptophan depletion. Ro4368554 is applicable for research related to memory impairments.</p>
    Formule :C19H21N3O2S
    Couleur et forme :Solid
    Masse moléculaire :355.454
  • GABA-IN-4

    CAS :
    <p>GABA-IN-4 (Compound 17) is a derivative of N-(indol-3-ylglyoxylyl)benzylamine. It exhibits high affinity for the benzodiazepine receptor (BzR), the binding site within the GABAA receptor complex, with a Ki value of 67 nM. Benzodiazepines are widely used as anxiolytic, sedative-hypnotic, and anticonvulsant agents.</p>
    Formule :C17H13ClN2O2
    Couleur et forme :Solid
    Masse moléculaire :312.75
  • (+)-Cevimeline hydrochloride hemihydrate


    <p>(+)-Cevimeline HCl hemihydrate is a muscarinic agonist for dry mouth in Sjogren's with rapid absorption, differing metabolism in species.</p>
    Formule :C10H19ClNO1·5S
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :244.78
  • MAO-B-IN-10


    <p>MAO-B-IN-10: Potent, selective MAO-B inhibitor; crosses blood-brain barrier; IC50 5.3 μM; reduces Aβ aggregation 58.2%, disaggregates 43.3%.</p>
    Formule :C23H26N2O4
    Couleur et forme :Solid
    Masse moléculaire :394.46
  • FP0429

    CAS :
    <p>FP0429 is an agonist of mGlu4.</p>
    Formule :C10H12N2O7
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :272.21
  • 2,6-Dimethoxybenzylamine hydrochloride

    CAS :
    <p>2,6-Dimethoxybenzylamine hydrochloride (Compound 5) exhibits reversible inhibitory activity against copper amine oxidase (CAO) and inhibits benzylamine oxidase (BAO) and monoamine oxidase B (MAO B) with IC50 values of 120 μM and 190 μM, respectively.</p>
    Formule :C9H14ClNO2
    Couleur et forme :Solid
    Masse moléculaire :203.666
  • BChE-IN-38

    CAS :
    <p>BChE-IN-38 (compound 13) is a potent BChE inhibitor, with Ki values of 62.05, 28.78, 14.09, and 1.15 nM for hCAI, hCAII, AChE, and BChE, respectively. BChE-IN-38 also demonstrates cytotoxic activity.</p>
    Formule :C27H20N4
    Couleur et forme :Solid
    Masse moléculaire :400.474
  • MADAM

    CAS :
    <p>MADAM demonstrates high affinity and selectivity for 5-HTT, with a Ki value of 1.6 nM. It is utilized as a PET radiotracer for visualizing serotonin transporters.</p>
    Formule :C16H20N2S
    Couleur et forme :Solid
    Masse moléculaire :272.408
  • S-8510 phosphate

    CAS :
    <p>S-8510 phosphate is an agonist of inverse Benzodiazepine (BDZ) receptor(Kis of 34.6 nM, 36.2 nM for –GABA and +GABA respectively).</p>
    Formule :C12H13N4O6P
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :340.23
  • MAO-B-IN-5

    CAS :
    <p>MAO-B-IN-5: potent, selective oral MAO-B inhibitor, IC50=0.204μM, potential for Parkinson's research.</p>
    Formule :C19H21FN2O2
    Degré de pureté :97.68%
    Couleur et forme :Solid
    Masse moléculaire :328.38
  • LP 12 hydrochloride hydrate


    <p>LP 12 hydrochloride hydrate: potent, selective 5-HT7 agonist (Ki: 0.13 nM); less affinity for D2, 5-HT1A/2A receptors.</p>
    Formule :C32H39N3O·HCl·xH2O
    Couleur et forme :Solid
  • 5-HT1A antagonist 1


    <p>Compound 6f is a potent, selective 5-HT1A receptor blocker (Ki: 35 nM), useful in CNS disorder research.</p>
    Formule :C23H29ClN6O2
    Couleur et forme :Solid
    Masse moléculaire :456.97
  • AChE-IN-22


    <p>AChE-IN-22 (10q) selectively inhibits AChE (IC50: 0.88 μM), less on BuChE (IC50: 10 μM), targets CAS and PAS, useful in Alzheimer's research.</p>
    Formule :C21H20N4O5S
    Couleur et forme :Solid
    Masse moléculaire :440.47
  • Mesulergine hydrochloride

    CAS :
    <p>5-HT2A and 2C receptor antagonist</p>
    Formule :C18H27ClN4O2S
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :398.95
  • BF-168

    CAS :
    <p>BF-168 is a candidate probe for PET and specifically recognizes both neuritic and diffuse plaques (Ki: 6.4 nM for Aβ1-42).</p>
    Formule :C18H17FN2O2
    Couleur et forme :Solid
    Masse moléculaire :312.34
  • 5-IAI hydrochloride

    CAS :
    <p>5-IAI hydrochloride is a psychoactive analog of para-iodoamphetamine. 5-IAI hydrochloride significantly reduces serotonin uptake sites and hippocampal serotonin levels in rats.</p>
    Formule :C9H11ClIN
    Couleur et forme :Solid
    Masse moléculaire :295.548
  • Notch inhibitor 1

    CAS :
    <p>Notch inhibitor 1 blocks Notch 1/3 (IC50: 7.8/8.5 nM) and aids cancer research.</p>
    Formule :C26H25F7N4O3
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :574.49
  • Dihydro-β-erythroidine hydrobromide

    CAS :
    <p>Dihydro-β-erythroidine hydrobromide(DHβE) is a potent, oral active and competitive antagonist of neuronal nicotinic acetylcholine receptors (nAChRs).</p>
    Formule :C16H22BrNO3
    Degré de pureté :98%
    Couleur et forme :White Solid
    Masse moléculaire :356.26
  • Aβ42-IN-1

    CAS :
    <p>Aβ42-IN-1, compound 1v, is a novel, potent and orally active γ-secretase modulator (GSM).</p>
    Formule :C29H27ClN4O2
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :499
  • AChE/BuChE-IN-3

    CAS :
    <p>AChE/BuChE-IN-3 inhibits AChE (IC50: 0.65 μM), BuChE (IC50: 5.77 μM), crosses BBB, and hinders Aβ1-42 aggregation for Alzheimer's research.</p>
    Formule :C30H30F3N3O6
    Couleur et forme :Solid
    Masse moléculaire :585.57
  • D3/5-HT receptor modulator-1

    CAS :
    <p>D3/5-HT receptor modulator-1 (compound 5i) is a selective antagonist of the dopamine D3 and 5-HT2A receptors, and a partial agonist at the 5-HT1A receptor. It exhibits Ki values of 4.5 nM, 11.9 nM, and 15.3 nM for the dopamine D3, 5-HT2A, and 5-HT1A receptors respectively. The compound shows lower affinity for the dopamine D2 receptor, 5-HT2C receptor, and hERG channel. D3/5-HT receptor modulator-1 possesses atypical antipsychotic properties.</p>
    Formule :C24H29N3O2
    Couleur et forme :Solid
    Masse moléculaire :391.506
  • Revexepride

    CAS :
    <p>Revexepride, a 5-HT4 agonist, may boost CYP3A4, used for treating GERD.</p>
    Formule :C21H32ClN3O4
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :425.95
  • Dual AChE-MAO B-IN-1


    <p>Dual AChE-MAO B-IN-1: orally active CNS-permeable, safe, stable neuroprotective agent; AChE IC50=550 nM, MAO-B IC50=8.2 nM.</p>
    Formule :C23H25F2NO4
    Couleur et forme :Solid
    Masse moléculaire :417.45
  • 25B-NBOH hydrochloride

    CAS :
    <p>25B-NBOH hydrochloride is a phenethylamine that exhibits high affinity for serotonin (5-HT) receptors 5-HT2A and 5-HT2C, with pKi values of 8.3 and 9.4, respectively.</p>
    Formule :C17H21BrClNO3
    Couleur et forme :Solid
    Masse moléculaire :402.711
  • LY 215840

    CAS :
    <p>5-HT2/5-HT7 receptor antagonist</p>
    Formule :C24H33N3O2
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :395.54
  • AChE-IN-84

    CAS :
    <p>AChE-IN-84 (compound 21) is an inhibitor of AChE.</p>
    Formule :C6H15Br2N
    Couleur et forme :Solid
    Masse moléculaire :260.998
  • Moxetomidate

    CAS :
    <p>Moxetomidate is a GABAA receptor (GABAA receptor) agonist with hypnotic properties.</p>
    Formule :C15H18N2O3
    Couleur et forme :Solid
    Masse moléculaire :274.315
  • HW161023

    CAS :
    <p>HW161023 (compound) is an orally active inhibitor of AP2 associated protein kinase 1 (AAK1), exhibiting IC50 values of 5.4 nM for AAK1 and 11.9 μM for hERG. HW161023 can suppress pain response in a rat model of chronic sciatic nerve compression injury.</p>
    Formule :C20H24F2N4O
    Couleur et forme :Solid
    Masse moléculaire :374.428
  • R-96544 hydrochloride

    CAS :
    <p>5-HT2 receptor antagonist</p>
    Formule :C22H29NO3
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :355.47
  • PTCA

    CAS :
    <p>PTCA is a potent ligand for Ca2+/calmodulin-dependent protein kinase II α (CaMKIIα), with a pKi value of 7.2.</p>
    Formule :C10H5Cl2NO2S
    Couleur et forme :Solid
    Masse moléculaire :274.123
  • (R)-Norfluoxetine

    CAS :
    <p>(R)-Norfluoxetine is the (R)-enantiomer of Norfluoxetine. It functions as a potent serotonin reuptake inhibitor, with a Ki value of 13 nM. This compound is utilized in the research of depression.</p>
    Formule :C16H16F3NO
    Couleur et forme :Solid
    Masse moléculaire :295.299
  • BChE-IN-5


    <p>BChE-IN-5: potent, selective BChE inhibitor (IC50: 2.8 nM), more effective on hBChE, potential in Alzheimer's research.</p>
    Formule :C30H42N4O
    Couleur et forme :Solid
    Masse moléculaire :474.68
  • AChE-IN-83

    CAS :
    <p>AChE-IN-83 (compound f1) is an AChE inhibitor that suppresses nematode growth and acetylcholinesterase activity in rice seeds while being safe for the seeds. It specifically targets Aphelenchoides besseyi, with an LC50 of 19.0 μg/mL over 48 hours. AChE-IN-83 impedes nematode populations and behaviors in rice seeds, damages the nematode cuticle, and induces reactive oxygen species, lipofuscin, and lipid generation within the nematodes.</p>
    Formule :C10H7ClN2O2S
    Couleur et forme :Solid
    Masse moléculaire :254.693
  • 5-HT1A modulator 4

    CAS :
    <p>5-HT1A modulator 4 (Compound 1) is a ligand for the 5-HT receptor, with Ki values of 2.18 μM for 5-HT1A and 19.7 μM for 5-HT2A.</p>
    Formule :C9H14N4
    Couleur et forme :Solid
    Masse moléculaire :178.234
  • MMB-4

    CAS :
    <p>MMB-4 is an oxime that can reactivate cholinesterases (cholinesterases) which have been inactivated due to exposure to organophosphates such as Sarin or Soman.</p>
    Formule :C13H14Br2N4O2
    Couleur et forme :Solid
    Masse moléculaire :418.084
  • MAO-B-IN-40

    CAS :
    <p>MAO-B-IN-40 (3a) is an inhibitor of MAOB, exhibiting an IC50 value of 0.493 μM against hMAOB, and demonstrates significant neuroprotective and antioxidant effects. MAO-B-IN-40 (3a) is applicable in Parkinson's disease research.</p>
    Formule :C17H15N3O3
    Couleur et forme :Solid
    Masse moléculaire :309.319
  • (S)-Praziquantel

    CAS :
    <p>(S)-Praziquantel is the inactive isomer of R-praziquantel.</p>
    Formule :C19H24N2O2
    Couleur et forme :Solid
    Masse moléculaire :312.406
  • PF-06751979

    CAS :
    <p>PF-06751979 is an inhibitor of β-site amyloid precursor protein cleaving enzyme 1 (BACE1) (IC50 of 7.3 nM in BACE1 binding assay).</p>
    Formule :C18H19F2N5O3S2
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :455.5
  • LY3020371 hydrochloride

    CAS :
    LY3020371 HCl: potent mGlu2/3 antagonist, antidepressant-like; Ki: 5.3/2.5 nM, IC50: 16.2 nM for cAMP inhibition.
    Formule :C15H16ClF2NO5S
    Couleur et forme :Solid
    Masse moléculaire :395.81
  • SEP-363856 mesylate

    CAS :
    <p>SEP-363856 (SEP-856) mesylate is an orally active compound that acts as an agonist for both TAAR1 and 5-HT1A receptors. This compound exhibits antipsychotic activity in the central nervous system and has potential for the study of schizophrenia.</p>
    Formule :C10H17NO4S2
    Couleur et forme :Solid
    Masse moléculaire :279.38
  • RTIOXA-43

    CAS :
    <p>RTIOXA-43 is an OX2R/OX1R (orexin receptor) dual agonist that increases wakefulnesand is commonly used in studies related to narcolepsy and neural signaling.</p>
    Formule :C37H37N5O5S
    Degré de pureté :99.17%
    Couleur et forme :Solid
    Masse moléculaire :663.79
  • Nafimidone hydrochloride

    CAS :
    <p>Nafimidone hydrochloride, an antiepileptic agent, inhibits acetylcholinesterase, protects neurons, and ameliorates cognitive decline. It is utilized in epilepsy research.</p>
    Formule :C15H13ClN2O
    Couleur et forme :Solid
    Masse moléculaire :272.73
  • DA-8031

    CAS :
    <p>DA-8031 is a selective and orally active serotonin reuptake inhibitor. It is utilized in research related to premature ejaculation (PE).</p>
    Formule :C21H24N2O2
    Couleur et forme :Solid
    Masse moléculaire :336.43
  • Sulamserod hydrochloride

    CAS :
    <p>Sulamserod hydrochloride is a 5-HT4 receptor antagonist. It is utilized in research related to gastrointestinal disorders.</p>
    Formule :C19H29Cl2N3O5S
    Couleur et forme :Solid
    Masse moléculaire :482.42
  • LY 541850

    CAS :
    <p>LY541850 is a selective orthosteric mGlu2 agonist and mGlu3 antagonist with IC50 values of 0.161 μM and 0.038 μM, respectively.LY 541850 is claimed from human</p>
    Formule :C9H13NO4
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :199.2
  • Rodatristat ethyl

    CAS :
    <p>Rodatristat ethyl is an oral TPH1 inhibitor reducing 5-HT levels &amp; lowering PAH at low doses.</p>
    Formule :C29H31ClF3N5O3
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :590.04
  • BACE1-IN-5

    CAS :
    <p>BACE1-IN-5 inhibits BACE1 (IC50: 9.1 nM) &amp; Aβ production (IC50: 0.82 nM), enhances hERG inhibition &amp; P-gp efflux.</p>
    Formule :C18H16F5N5O2S
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :461.41
  • DL-AP5 lithium

    CAS :
    <p>DL-AP5 (2-APV) lithium is a competitive antagonist of the NMDA (N-Methyl-D-aspartate) receptor. It exhibits notable analgesic activity and specifically blocks channels in the rabbit retina.</p>
    Formule :C5H11LiNO5P
    Couleur et forme :Solid
    Masse moléculaire :203.06
  • Tipindole

    CAS :
    <p>Tipindole is a serotonin antagonist utilized in research related to depression.</p>
    Formule :C16H20N2O2S
    Couleur et forme :Solid
    Masse moléculaire :304.41
  • Elzasonan hydrochloride

    CAS :
    <p>Elzasonan hydrochloride is a serotonin 1B and serotonin 1D receptor antagonist. It is utilized in the study of depression.</p>
    Formule :C22H24Cl3N3OS
    Couleur et forme :Solid
    Masse moléculaire :484.87
  • hMAO-B-IN-10


    <p>hMAO-B-IN-10 (compound 7) is an inhibitor of MAO-A/B with IC50 values of 424.1 nM and 177.9 nM, respectively. It has demonstrated neuroprotective effects in the MPTP-induced mouse model of Parkinson's Disease (PD).</p>
    Formule :C16H12N4O4
    Couleur et forme :Solid
    Masse moléculaire :324.29
  • AGH-107

    CAS :
    <p>AGH-107 is a highly selective 5-HT7 receptor agonist that can cross the blood-brain barrier, featuring a Ki value of 6 nM and an EC50 value of 19 nM. Demonstrating high selectivity for central nervous system targets, AGH-107 also exhibits high metabolic stability and low toxicity in HEK-293 and HepG2 cell cultures.</p>
    Formule :C13H12IN3
    Couleur et forme :Solid
    Masse moléculaire :337.16
  • CL-13


    <p>CL-13 is an inhibitor of butyrylcholinesterase (BChE), exhibiting an IC50 of 1.15 μM and a selectivity index (SI) of 9.2 for acetylcholinesterase. It demonstrates antioxidative activity in SH-SY5Y cells with a DPPHEC50 of 47.01 μM and has the capacity to chelate metals involved in Aβ aggregation and/or oxidative stress, showing no neurotoxicity at concentrations up to 50 μM. CL-13 can also reverse scopolamine-induced cognitive impairments without affecting motor abilities in mice.</p>
    Formule :C29H32N4OS
    Couleur et forme :Solid
    Masse moléculaire :484.66
  • (S)-Norfluoxetine

    CAS :
    <p>(S)-Norfluoxetine, the S enantiomer of Norfluoxetine, functions as a selective serotonin reuptake inhibitor. It enhances allopregnanolone levels and reduces aggression in socially isolated mice.</p>
    Formule :C16H16F3NO
    Couleur et forme :Solid
    Masse moléculaire :295.3
  • Etoperidone

    CAS :
    <p>Etoperidone is an antidepressant that acts as an orally active reuptake inhibitor for serotonin (serotonin) and noradrenaline (nor-adrenaline). It demonstrates specific binding affinities (Kd) for several receptors: 36 nM at the 5-HT2 receptor, 38 nM at the α1-adrenergic receptor (α1-adrenergic receptor), 85 nM at the 5-HT1A receptor, and 570 nM at the α2-adrenergic receptor (α2-adrenergic receptor).</p>
    Formule :C19H28ClN5O
    Couleur et forme :Solid
    Masse moléculaire :377.91
  • AM-6494

    CAS :
    <p>AM-6494 is a potent and orally active BACE1 inhibitor (IC50: 0.4 nM) with in vivo selectivity over BACE2 (IC50: 18.6 nM).</p>
    Formule :C22H21F2N5O3S
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :473.5
  • BACE1-IN-4

    CAS :
    <p>BACE1-IN-4 is a potent and highly selective BACE1 inhibitor (IC50: 3.8 nM; Ki: 1.9 nM), more selective at BACE1 over BACE2.</p>
    Formule :C21H23F2N5O4S2
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :511.57
  • Aβ42 agonist-1

    CAS :
    <p>Aβ42 agonist-1 is a small molecule compound with anti-cancer activity and NF-κB inhibitory properties, inducing Aβ42 aggregation.</p>
    Formule :C15H11NO2
    Degré de pureté :99.77%
    Couleur et forme :Solid
    Masse moléculaire :237.25
  • LB-102

    CAS :
    <p>LB-102 is an orally active inhibitor of dopamine D2, D3, and serotonin 5-HT7 receptors, utilized in the study of schizophrenia and other psychiatric disorders.</p>
    Formule :C18H29N3O4S
    Couleur et forme :Solid
    Masse moléculaire :383.51
  • SB 243213 dihydrochloride

    CAS :
    <p>SB 243213 dihydrochloride is an orally active, selective and high-affinity antagonist of 5-hydroxytryptamine (5-HT)2C receptor(pKi of 9.37 and a pKb of 9.8 for</p>
    Formule :C22H21Cl2F3N4O2
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :501.33
  • PXS-4787 hydrochloride

    CAS :
    <p>PXS-4787 hydrochloride is a specific and potent pan-lysyl oxidase inhibitor that effectively eliminates the activity of lysyl oxidase. It exhibits varying IC50 values against different forms of the enzyme, including 2 μM (Bovine LOX), 3.2 μM (rh LOXL1), 0.6 μM (rh LOXL2), 1.4 μM (rh LOXL3), and 0.2 μM (rh LOXL4). In addition, PXS-4787 hydrochloride reduces the deposition and cross-linking of collagen I secreted by human fibroblasts.</p>
    Formule :C10H13ClFNO2S
    Couleur et forme :Solid
    Masse moléculaire :265.73
  • Relicpixant

    CAS :
    <p>Relicpixant is a potent purine receptor (P2X) antagonist.</p>
    Formule :C20H19ClF2N4O5S
    Couleur et forme :Solid
    Masse moléculaire :500.9
  • Nedemelteon

    CAS :
    <p>Nedemelteon is an agonist of the melatonin receptor (melatonin receptor).</p>
    Formule :C15H18N2O2
    Couleur et forme :Solid
    Masse moléculaire :258.32
  • BGT1-IN-1

    CAS :
    <p>BGT1-IN-1 (compound 9) is an effective inhibitor of BGT1, demonstrating IC50 values of 13.9 µM for hBGT1 and 58.3 µM for GAT3. It exhibits no cytotoxic effects and possesses neuroprotective activity.</p>
    Formule :C6H9NO2
    Couleur et forme :Solid
    Masse moléculaire :127.14
  • Iclepertin

    CAS :
    <p>Iclepertin (BI-425809) is a GlyT1 inhibitor.Iclepertin is used for the treatment of Alzheimer;s disease and other CNS disorders.</p>
    Formule :C20H18F6N2O5S
    Degré de pureté :98.89% - 98.93%
    Couleur et forme :Solid
    Masse moléculaire :512.42
  • SB-224289 hydrochloride

    CAS :
    <p>SB-224289 hydrochloride (SB-224289A) is a selective antagonist of 5-HT1B receptor, with anxiolytic effect.</p>
    Formule :C32H33ClN4O3
    Degré de pureté :97.82% - 98.99%
    Couleur et forme :Solid
    Masse moléculaire :557.08
  • BMS 299897

    CAS :
    <p>BMS 299897, a sulfonamide γ-secretase inhibitor, inhibits Aβ production with an IC50 of 7 nM in HEK293 cells overexpressing APP.</p>
    Formule :C24H21ClF3NO4S
    Degré de pureté :99.82%
    Couleur et forme :Solid
    Masse moléculaire :511.94