Neuroscience
Les inhibiteurs en neurosciences sont des composés conçus pour moduler l'activité de protéines, d'enzymes ou de récepteurs spécifiques au sein du système nerveux. Ces inhibiteurs sont cruciaux pour étudier les mécanismes moléculaires sous-jacents au fonctionnement neuronal, à la transmission synaptique et aux maladies neurodégénératives. En ciblant les récepteurs des neurotransmetteurs, les canaux ioniques et les voies de signalisation, les inhibiteurs en neurosciences facilitent l'exploration du fonctionnement cérébral et le développement de stratégies thérapeutiques pour des troubles neurologiques tels que la maladie d'Alzheimer, de Parkinson et l'épilepsie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs en neurosciences de haute qualité pour soutenir vos recherches en neurobiologie, neuropharmacologie et sciences cognitives.
Sous-catégories appartenant à la catégorie "Neuroscience"
- récepteur 5-HT(940 produits)
- ACK(1 produits)
- AChR(574 produits)
- ATP Citrate Lyase(16 produits)
- Récepteur adrénergique(2.939 produits)
- BACE(36 produits)
- Bêta-amyloïde(204 produits)
- CaMK(68 produits)
- COX(562 produits)
- Récepteur de la dopamine(407 produits)
- Récepteur GABA(336 produits)
- Gamma-sécrétase(59 produits)
- GluR(255 produits)
- GlyT(24 produits)
- Récepteur de l'histamine(358 produits)
- LRRK2(33 produits)
- Récepteur de la mélatonine(24 produits)
- NMDAR(28 produits)
- Récepteur OX(40 produits)
- Récepteur opioïde(296 produits)
Affichez 12 plus de sous-catégories
5400 produits trouvés pour "Neuroscience"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
CP 96021
CAS :<p>"CP 96021 is an antagonist of 5-HT1/2 receptors, with anti-inflammatory and anti-ulcer effects for treating GI tract and asthma."</p>Formule :C29H21FN4OSDegré de pureté :97.81% - 99.62%Couleur et forme :SoildMasse moléculaire :492.57PNU-282987 free base
CAS :<p>PNU-282987 is an α7 nAChR agonist (EC50=154 nM) and a 5-HT3 antagonist (IC50=4541 nM) for nervous system research.</p>Formule :C14H17ClN2ODegré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :264.75Femoxetine hydrochloride
CAS :<p>Femoxetine hydrochloride is a selective 5-hydroxytryptamine reuptake inhibitor used in the study of migraine, depression and eating disorders.</p>Formule :C20H26ClNO2Degré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :347.88R 59-022 hydrochloride
CAS :<p>R 59-022 hydrochloride is a 5-HT antagonist, PKC activator, DGK inhibitor (IC50: 2.8 µM), and modulates lipid production in platelets and neutrophils.</p>Formule :C27H27ClFN3OSDegré de pureté :97.7%Couleur et forme :SolidMasse moléculaire :496.04DA-6886
CAS :<p>DA-6886 is a 5-HT4 agonist, relaxes rat oesophagus, with 1000x selectivity over hERG channels, pIC50: 4.3.</p>Formule :C19H28Cl2N6O2Degré de pureté :99.28% - 99.91%Couleur et forme :SolidMasse moléculaire :443.37AZD 9272
CAS :<p>AZD 9272 is a brain-permeable mGluR5 antagonist for the study of gastroesophageal reflux.</p>Formule :C14H6F2N4ODegré de pureté :98.29%Couleur et forme :SolidMasse moléculaire :284.22Faxeladol
CAS :<p>Faxeladol: adrenergic, serotonin inhibitor & opioid agonist for neurological studies.</p>Formule :C15H23NODegré de pureté :98.09% - 98.77%Couleur et forme :SolidMasse moléculaire :233.35Cirsimaritin
CAS :<p>Cirsimaritin has anti-bacterial, anti-inflammatory, anti-tumor, antioxidant effects, and protects kidneys; it weakly targets GABAA receptors.</p>Formule :C17H14O6Degré de pureté :99.9%Couleur et forme :SolidMasse moléculaire :314.29(Z)-Thiothixene
CAS :<p>(Z)-Thiothixene (Thiothixene) is an antagonist of serotonergic receptor.</p>Formule :C23H29N3O2S2Degré de pureté :99.21%Couleur et forme :Yellow To Yellow With A Tan Cast PowderMasse moléculaire :443.63Divaplon
CAS :<p>Divaplon is a GABA receptor agonist (IC50: 0.056 µM) that displays non-sedating anxiolytic behavioral characteristics in a rat model of anxiety.</p>Formule :C17H17N3O2Degré de pureté :97.44% - 98.25%Couleur et forme :SolidMasse moléculaire :295.34Cilansetron
CAS :<p>Cilansetron is an effective and selective 5-HT3 receptor antagonist that can be used for related diseases caused by colitis.</p>Formule :C20H21N3ODegré de pureté :99.82% - 99.98%Couleur et forme :SolidMasse moléculaire :319.4E6801
CAS :<p>E6801: selective 5-HT6 agonist for research in dementia, Parkinson's, depression, obesity, epilepsy, anxiety, etc.</p>Formule :C17H18ClN5O2S2Degré de pureté :96.32% - 99.53%Couleur et forme :SolidMasse moléculaire :423.94GSK-1482160
CAS :<p>GSK-1482160 is a CNS-penetrant negative allosteric modulator of P2X7 receptor with oral activity.</p>Formule :C14H14ClF3N2O2Degré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :334.72MNI 137
CAS :<p>MNI 137 is a negative allosteric modulator of mGlu2. MNI 137 inhibits glutamate-induced calcium mobilization with IC50s of 8.3 and 12.6 nM for human and rat.</p>Formule :C15H9BrN4ODegré de pureté :97.49%Couleur et forme :SolidMasse moléculaire :341.16Itasetron
CAS :<p>Itasetron, a 5-HT3 antagonist, prevents memory loss in rats and has antiemetic effects in cancer treatments.</p>Formule :C16H20N4O2Degré de pureté :98.58% - 99.33%Couleur et forme :SolidMasse moléculaire :300.36CGP 37849
CAS :<p>CGP 37849: oral NMDA antagonist (Ki=35 nM), anticonvulsant, with antidepressant/anxiolytic effects.</p>Formule :C6H12NO5PDegré de pureté :99.87%Couleur et forme :White SolidMasse moléculaire :209.14W-9 hydrochloride
CAS :<p>W-9 hydrochloride is a calmodulin antagonist.</p>Formule :C16H22Cl2N2O2SDegré de pureté :98.9%Couleur et forme :SolidMasse moléculaire :377.33LY-2300559
CAS :<p>LY-2300559 is an agonist of metabotropic glutamate receptor 2 (mGluR2) and can be used in studies about the treatment of migraine.</p>Formule :C26H26O6Degré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :434.485-HT2 antagonist 1
CAS :<p>5-HT2 antagonist 1 is a potent 5-HT2 receptor antagonist, has weak α1 adrenoceptor blocking activity.</p>Formule :C22H29FN4O2Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :400.49BI-1408
CAS :<p>BI-1408 is a modulator potent of γ secretase (IC50: 0.04 μM for Aβ42).</p>Formule :C22H23FN6Degré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :390.46Desformylflustrabromine hydrochloride
CAS :<p>Desformylflustrabromine hydrochloride (dFBr hydrochloride) is a selective agonist of nicotinic acetylcholine receptor (nAChR) in α4β2 neurons, with pEC50 of 6.</p>Formule :C17H12INO5Degré de pureté :98.12%Couleur et forme :SolidMasse moléculaire :437.19Ezeprogind disulfate
CAS :<p>Ezeprogind disulfate: neurotrophic inducer targeting neurodegeneration causes like Abeta, tau; for neurological disorder research.</p>Formule :C25H48N6O8S2Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :624.81PPI-1019
CAS :<p>PPI-1019 is an APP (β-amyloid A4) inhibitor for the treatment of neurological disorders and the study of Alzheimer's disease (AD).</p>Formule :C36H54N6O5Degré de pureté :95.16% - 98.16%Couleur et forme :SolidMasse moléculaire :650.85Aβ-IN-1
CAS :<p>Aβ-IN-1 is a novel, potent and orally active γ-secretase modulator (GSM).</p>Formule :C35H49NDegré de pureté :99.1%Couleur et forme :SoildMasse moléculaire :483.77Perphenazine dihydrochloride
CAS :<p>Perphenazine dihydrochloride: Oral dopamine, histamine-1 antagonist; targets D2, D3, 5-HT2A, Alpha-1A; may treat psychiatric disorders, cancer.</p>Formule :C21H28Cl3N3OSDegré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :476.89Ecopipam
CAS :<p>Ecopipam: orally active, selective dopamine D1/D5 antagonist (Ki: 1.2 nM/2.0 nM). 40x more selective over D2/D4/5-HT/α2a. For schizophrenia, obesity research.</p>Formule :C19H20ClNODegré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :313.82SPD-473 citrate
CAS :<p>SPD-473 citrate is an inhibitior of serotonin/dopamine/norepinephrine reuptake.</p>Formule :C23H31Cl2NO8SDegré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :552.47Roxindole
CAS :<p>Roxindole: dopamine agonist, serotonin reuptake inhibitor, 5-HT1A agonist, developed for schizophrenia.</p>Formule :C23H26N2ODegré de pureté :98.03% - 98.93%Couleur et forme :SolidMasse moléculaire :346.47Nexopamil
CAS :<p>Nexopamil (LU-49938) is a dual calcium channel and 5-HT2A receptor antagonist that inhibits cell contraction and growth.</p>Formule :C24H40N2O3Degré de pureté :97.87% - >99.99%Couleur et forme :SolidMasse moléculaire :404.59Tiospirone
CAS :<p>Tiospirone (BMY 13859-1 free base) is a 5-HT2 receptor antagonist and a dopamine blocker used in the study of neurological disorders such as schizophrenia.</p>Formule :C24H32N4O2SDegré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :440.6Lensiprazine
CAS :<p>Lensiprazine (SLV314) is a potent dopamine D(2) receptor antagonist that acts as a serotonin reuptake inhibitor , and can be used to study bipolar disorder and</p>Formule :C24H27FN4O2Degré de pureté :98.04%Couleur et forme :SolidMasse moléculaire :422.5H-9 dihydrochloride
CAS :<p>H-9 dihydrochloride: Strong PKA inhibitor, curbs 5-HT response and EGF signaling, affects pharyngeal function.</p>Formule :C11H15Cl2N3O2SDegré de pureté :97.3%Couleur et forme :SolidMasse moléculaire :324.235-HT1A modulator 1
CAS :<p>5-HT1A modulator 1 displays very high affinities for the 5-HT1A, α1-adrenergic receptor, and D2 receptor (IC50s = 2 nM, 10 nM, and 40 nM).</p>Formule :C21H25N3O2SDegré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :383.51Pimethixene maleate
CAS :<p>Pimethixene maleate (Pimetixene maleate) is a 5-HT2B receptor antagonist with sedative activity that can be used to study dry cough in children.</p>Formule :C23H23NO4SDegré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :409.5BMY-14802 hydrochloride
CAS :<p>BMY-14802 hydrochloride (BMS 181100 hydrochloride) is a selective antagonist of σ receptor (IC50 = 112 nM) with antipsychotic effects.</p>Formule :C18H23ClF2N4ODegré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :384.852-BFI hydrochloride
CAS :<p>2-BFI hydrochloride: High-affinity I2 agonist; used in researching stroke and immune disease protection.</p>Formule :C11H11ClN2ODegré de pureté :99.94%Couleur et forme :SolidMasse moléculaire :222.67Ensaculin
CAS :<p>Ensaculin, a benzopyrone-piperazine compound, enhances memory, protects neurons, and may treat dementia.</p>Formule :C26H32N2O5Degré de pureté :99.17% - 99.67%Couleur et forme :SolidMasse moléculaire :452.54DMCM hydrochloride
CAS :<p>DMCM hydrochloride is a non-selective fully inverse agonist of benzodiazepine.</p>Formule :C17H19ClN2O4Degré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :350.8AMPA receptor antagonist-2
CAS :<p>AMPA receptor antagonist-2 is an AMPA receptor antagonist.</p>Formule :C18H17N3O4Degré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :339.35ELB-139
CAS :<p>ELB-139 is a GABA A receptor agonist. ELB139 increases 5-HT in the striatum and prefrontal cortex of rats.</p>Formule :C14H16ClN3ODegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :277.75Quinupramine
CAS :<p>Quinupramine: an oral antidepressant targeting the serotonin system; penetrates CNS; doesn’t affect β-adrenergic system.</p>Formule :C21H24N2Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :304.43VU 0285683
CAS :<p>VU 0285683 is a specific negative allosteric modulator of mGluR5 with a high affinity for the MPEP binding site. VU 0285683 shows anxiolytic-like activity.</p>Formule :C14H7FN4ODegré de pureté :99.98%Couleur et forme :SolidMasse moléculaire :266.23Aplindore Fumarate
CAS :<p>Aplindore Fumarate (DAB-452), a selective dopamine D2/D3 partial agonist, is used in Parkinson's and schizophrenia research.</p>Formule :C22H22N2O7Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :426.42Xanomeline
CAS :<p>Xanomeline: orally active, M1/M4 selective activator for neurological disorders; promising in trials, crosses blood-brain barrier, liver metabolized.</p>Formule :C14H23N3OSDegré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :281.42Otenzepad
CAS :<p>Otenzepad (AF-DX 116) is a selective antagonist of M2 mAChR with IC50s of 386 nM and 640 nM for rat heart and rabbit peripheral lung.</p>Formule :C24H31N5O2Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :421.54BPDBA
CAS :<p>BPDBA is an effective, selective, and non-competitive inhibitor of the betaine/GABA transporter (BGT-1), displaying inhibitory activity against human BGT-1 and</p>Formule :C19H20Cl2N2ODegré de pureté :99.37% - 99.95%Couleur et forme :SolidMasse moléculaire :363.28Repinotan
CAS :<p>Repinotan (BAY x 3702 free base) is a 5-HT1A receptor agonist used in acute ischemic stroke studies.</p>Formule :C21H24N2O4SDegré de pureté :99%Couleur et forme :SolidMasse moléculaire :400.49GR 46611
CAS :<p>GR 46611 is a selective 5-HT1B and 5-HT1D receptor agonist and can be used in studies about the treatment of epilepsy.</p>Formule :C23H27N3O2Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :377.48Sudoxicam
CAS :<p>Sudoxicam (4-Hydroxy-2-methyl-N-2-thiazolyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide) is a reversible antagonist of COX with anti-inflammatory, anti-edema</p>Formule :C13H11N3O4S2Degré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :337.37LM-1685
CAS :<p>LM-1685是一种有效且具有选择性的人单核细胞和全血中COX-2抑制剂，IC50分别为0.65 µM 和IC50 = 4.3 μM，是治疗炎症的潜在化合物。</p>Formule :C18H16ClNO4SDegré de pureté :98.16%Couleur et forme :SolidMasse moléculaire :377.84LRRK2-IN-7
CAS :<p>LRRK2-IN-7: potent, selective CNS-active LRRK2 inhibitor, IC50 0.9 nM, >1000x selectivity vs kinases/channels/CYPs.</p>Formule :C24H26N6ODegré de pureté :99.26%Couleur et forme :SolidMasse moléculaire :414.5ATC 0175 hydrochloride
CAS :<p>ATC 0175 hydrochloride is an orally active melanocyte concentrating hormone 1 receptor antagonist that is potent and selective.</p>Formule :C23H26ClF2N5ODegré de pureté :99.98%Couleur et forme :SolidMasse moléculaire :461.93DSP-0565
CAS :<p>DSP-0565 is a broad-spectrum anti-epileptic with a high safety margin and effectiveness in several convulsant models.</p>Formule :C14H12FNODegré de pureté :99.51% - 99.56%Couleur et forme :SolidMasse moléculaire :229.25Muscimol HBr
CAS :<p>Muscimol HBr (Agarin HBr) is an agonist of GABAA receptor.</p>Formule :C4H7BrN2O2Degré de pureté :98.13%Couleur et forme :Off-White PowderMasse moléculaire :195.01Felcisetrag
CAS :<p>Felcisetrag (TD-8954), an oral 5-HT4 agonist with GI prokinetic effects, has a high affinity (pKi 9.4) for h5-HT4(c) receptors.</p>Formule :C25H37N5O3Degré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :455.59Ricasetron
CAS :<p>Ricasetron (Brl 46470) is a 5-HT3 receptor antagonist with pro-axonal lysing properties and is used in the study of anxiety disorders and anxiety disorders.</p>Formule :C19H27N3ODegré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :313.44Viloxazine
CAS :<p>Viloxazine (Viloxazin) (Viloxazin) is a dual-action compound that functions as a norepinephrine reuptake inhibitor and exhibits potent agonistic activity</p>Formule :C13H19NO3Degré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :237.29Piromelatine
CAS :<p>Piromelatine is an agonist of melatonin MT1/MT2 receptors, 5-HT1A and 5-HT1D, and an antagonist of 5-HT2B.Piromelatine has antinociceptive activity with</p>Formule :C17H16N2O4Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :312.32(E/Z)-SIB-1893
CAS :<p>(E/Z)-SIB-1893 (SIB 1893) is the racemate of (E)-SIB-1893 and (Z)-SIB-1893.</p>Formule :C14H13NDegré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :195.26LY-2624803
CAS :<p>LY-2624803 is a 5-HT2A receptor antagonist and histamine receptor inverse agonist that can be used to improve slow wave sleep.</p>Formule :C22H25N3O3Degré de pureté :99.78% - 99.97%Couleur et forme :SolidMasse moléculaire :379.455-HT6/7 antagonist 1
CAS :<p>5-HT6/7 antagonist 1 is a dual 5-HT6/7/2A and D2 receptor antagonist for the study of dementia and Alzheimer's disease.</p>Formule :C22H20FN3O3Degré de pureté :98.78% - 99.26%Couleur et forme :SolidMasse moléculaire :393.41DQP-26
CAS :<p>DQP-26, a potent negative allosteric modulator of NMDA receptors (NMDARs), exhibits IC50 values of 0.77 μM for GluN2C and 0.44 μM for GluN2D subunits,</p>Formule :C28H21Cl2N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :534.39Abaperidone
CAS :<p>Abaperidone is an atypical antipsychotic, antagonizes 5-HT2A (IC50=6.2 nM) and D2 receptors (IC50=17 nM), reduces hsp70 mRNA in rat brains.</p>Formule :C25H25FN2O5Degré de pureté :98.22%Couleur et forme :SolidMasse moléculaire :452.47BACE1-IN-10
CAS :<p>BACE1-IN-10 is a potent inhibitor of BACE1, demonstrating sub-micromolar activity against recombinant BACE1 (rBACE1) [1].</p>Formule :C33H49N5O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :675.84Tiotropium Bromide hydrate
CAS :<p>Tiotropium Bromide hydrate is a potent, long-lasting anticholinergic bronchodilator for COPD, with high affinity for muscarinic receptors M1, M2, and M3.</p>Formule :C19H24BrNO5S2Degré de pureté :98.44% - 99.41%Couleur et forme :SolidMasse moléculaire :490.43Aβ/tau aggregation-IN-3
CAS :<p>Aβ/tau aggregation-IN-3 is a potent inhibitor of amyloid protein aggregation, exhibiting an IC50 value of 0.85 µM in an Aβ-Thioflavin T (Aβ-ThT) functional</p>Formule :C23H22N4O3Couleur et forme :SolidMasse moléculaire :402.45MAO-B-IN-13
CAS :<p>MAO-B-IN-13: a potent, reversible MAO-B inhibitor with BBB penetration, neuroprotective effects; used in Parkinson’s research (IC50=10nM).</p>Formule :C18H19NO3Couleur et forme :SolidMasse moléculaire :297.35AAK1-IN-2
CAS :<p>AAK1-IN-2, a potent (IC50=5.8 nM) AAK1 inhibitor, selective & brain-penetrant, is used for neuropathic pain studies.</p>Formule :C20H20N4Couleur et forme :SolidMasse moléculaire :316.4SB 258719
CAS :<p>SB 258719 is a selective antagonist of 5-HT7 receptor with pKi of 7.5.</p>Formule :C18H30N2O2SDegré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :338.51Zamifenacin fumarate
CAS :<p>Zamifenacin fumarate (UK-76654 fumarate) is a potent and gut-selective antagonist of muscarinic M3 receptor.</p>Formule :C31H33NO7Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :531.6Frovatriptan
CAS :<p>Frovatriptan, potent 5-HT 1B/D agonist, shows high cerebroselectivity and efficacy for migraine with aura.</p>Formule :C14H17N3OCouleur et forme :SolidMasse moléculaire :243.3L 687306
CAS :<p>L 687306 is a partial agonist of muscarinic M1 receptors. It is also a highly competitive antagonist at cardiac M2 receptors and ileal M3 muscarinic receptors.</p>Formule :C11H15N3OCouleur et forme :SolidMasse moléculaire :205.26BT-GSI
<p>BT-GSI: γ-secretase inhibitor targeting Notch, anti-myeloma & anti-resorptive for multiple myeloma/bone disease research.</p>Formule :C26H46BrN5O10P2Couleur et forme :SolidMasse moléculaire :730.52(S)-Renzapride
<p>(S)-Renzapride (BRL 24924), 5-HT4 agonist (Ki 115 nM), 5HT2b/5HT3 antagonist, for C-IBS study.</p>Formule :C16H22ClN3O2Couleur et forme :SolidMasse moléculaire :323.82FGIN-1-27
CAS :<p>FGIN-1-27 is a high-affinity agonist of the translocator protein and a specific peripheral benzodiazepine receptor (PBR) ligand(Ki = 5.0 nM).</p>Formule :C28H37FN2ODegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :436.6BMS-933043
CAS :<p>BMS-933043: α7 nAChR partial agonist, binds rat (Ki=3.3 nM) & human (Ki=8.1 nM), agonist with EC50=23.4 nM (calcium assay), 0.14-0.29 μM (electrophysiology).</p>Formule :C16H19N7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :325.37NAS-181
CAS :<p>NAS-181 is a potent and selective rat 5-hydroxytryptamine 1B (r5-HT1B) antagonist (Ki: 47 nM).NAS-181 enhances the accumulation of 5-HTP in rat brain regions.</p>Formule :C20H30N2O7SCouleur et forme :SolidMasse moléculaire :442.53Antioxidant agent-15
CAS :<p>Antioxidant agent-15 (Compound 4) demonstrates potent antioxidant inhibition activity, exhibiting an IC50 value of 15.44 nM.</p>Formule :C19H14O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :274.31Brilaroxazine
CAS :<p>Brilaroxazine (RP5063): multimodal dopamine/5-HT modulator, partial agonist at D2/D3/D4, 5-HT1A/2A, and antagonist at 5-HT2B/7.</p>Formule :C22H25Cl2N3O3Degré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :450.36MAO-B-IN-27
CAS :<p>MAO-B-IN-27 (Compound 12c), a monoamine oxidase B (MAO-B) inhibitor, exhibits a potent and selective inhibitory effect on hMAO-B, with an IC50 value of 8.9 nM,</p>Formule :C16H17ClF3NODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :331.765-HT2A receptor agonist-3
CAS :<p>5-HT2A receptor agonist-3 represents the highest selectivity for the human 5-HT2A receptor currently identified, exhibiting a K i of 2.5 nM.</p>Formule :C21H26BrNO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :420.34PZ-II-029
CAS :<p>PZ-II-029 is a modulator of α6β3γ2-selective GABAA channel.</p>Formule :C18H15N3O3Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :321.335-HT2A&5-HT2C agonist-1
CAS :<p>5-HT2A&5-HT2C agonist-1 (Example 2) is a dual-acting agent targeting the 5-HT2A and 5-HT2C receptors with respective IC50 values of 196 nM and 0.9 nM.</p>Formule :C14H20N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :232.32CP-122288
CAS :<p>CP-122288: potent, selective 5-HT1B/D/F agonist; inhibits plasma protein extravasation, neurogenic inflammation.</p>Formule :C16H23N3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :321.44AMPA receptor modulator-5
CAS :<p>AMPA Receptor Modulator-5 (Example 217) serves as an AMPA receptor modulator, utilized in neurological disease research [1].</p>Formule :C20H12F4N6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :412.34Wf-516
CAS :<p>Wf-516 is a 5-HT reuptake inhibitor (Kis: 5 nM and 40 nM for 5-HT1A receptor and 5-HT2A receptor in humans, respectively), and with potent antidepressant</p>Formule :C25H25Cl2N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :502.39Lanabecestat
CAS :<p>Lanabecestat (AZD3293) is a BACE1 inhibitor (Ki: 0.4 nM), Lanabecestat is used in the study of neurological diseases like Alzheimer's disease.</p>Formule :C26H28N4ODegré de pureté :98.55%Couleur et forme :SolidMasse moléculaire :412.53CGP 55845 hydrochloride
CAS :<p>CGP55845 hydrochloride is a potent and selective GABAB receptor antagonist with an IC 50 of 6 nM which can be used in neurological research [1] [2].</p>Formule :C18H23Cl3NO3PCouleur et forme :SolidMasse moléculaire :438.71BMS-983970
CAS :<p>BMS-983970 is an oral inhibitor of pan-Notch, and for the treatment of multiplecancers.</p>Formule :C26H26F4N4O3Couleur et forme :SolidMasse moléculaire :518.5VU0360172
CAS :<p>VU0360172 is a positive allosteric modulator of mGlu5 receptors (EC50 = 16 nM; Ki = 195 nM).</p>Formule :C18H15FN2ODegré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :294.32UNC9994
CAS :<p>UNC9994 is a β-arrestin-biased dopamine D₂ receptor agonist (β-arrestin EC50 = 50 nM; Emax = 97%) with robust in vivo antipsychotic drug-like activities.</p>Formule :C21H22Cl2N2OSCouleur et forme :SolidMasse moléculaire :421.38Gepirone
CAS :<p>Gepirone is a 5-HT1A receptor agonist belonging to the buspirone family. Gepirone HCl possesses greater selectivity for the 5-HT1A receptor than SSRIs.</p>Formule :C19H29N5O2Degré de pureté :99.35% - 99.89%Couleur et forme :SolidMasse moléculaire :359.475-HT2C agonist-3 free base
CAS :<p>5-HT2C agonist-3 ((+)-19) free base, a selective 5-HT2C agonist (EC50: 24 nM, Ki: 78 nM), exhibits antipsychotic drug-like activity and inhibits Amphetamine-</p>Formule :C19H22FNO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :315.38NP-1815-PX
CAS :<p>NP-1815-PX is a P2X4R antagonist with anti-inflammatory and analgesic properties, inhibiting guinea pig tracheal, and can be used in chronic pain research.</p>Formule :C21H13N4NaO3SDegré de pureté :97.82% - 99.39%Couleur et forme :SolidMasse moléculaire :424.41Benoxaprofen
CAS :<p>Benoxaprofen (NSC-299582) is a non-steroidal anti-inflammatory drug.</p>Formule :C16H12ClNO3Degré de pureté :98.87%Couleur et forme :SolidMasse moléculaire :301.72Nevadistinel
CAS :<p>Nevadistinel (NYX-458; NYX-3054) is a positive allosteric modulator of the N-methyl-D-aspartate (NMDA) receptor, indicated for mitigating cognitive deficits</p>Formule :C15H18N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :274.32Timepidium bromide
CAS :<p>Timepidium bromide is an agent of anticholinergic.</p>Formule :C17H22BrNOS2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :400.4LG 50643
CAS :<p>LG 50643 is a muscarinic antagonist.</p>Formule :C24H34INO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :495.44TPA 023
CAS :<p>TPA 023 is a selective agonist of GABAA α2/α3 subtype (Kis = 0.19 - 0.41 nM).</p>Formule :C20H22FN7ODegré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :395.43GR 127935 hydrochloride
CAS :<p>5-HT1B/1D receptor antagonist</p>Formule :C29H32ClN5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :534.05Cyclophostin
CAS :<p>Cyclophostin is an irreversible inhibitor of acetylcholinesterase (AChE).</p>Formule :C8H11O6PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :234.14PHP 501 trifluoroacetate
CAS :<p>GABAA antagonist</p>Formule :C20H21N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :319.4Pomaglumetad methionil hydrochloride
CAS :<p>LY2140023 hydrochloride: oral methionine prodrug of LY404039, a selective mGlu2/3 agonist, studied for schizophrenia.</p>Formule :C12H19ClN2O7S2Degré de pureté :98.57%Couleur et forme :SolidMasse moléculaire :402.87(-)-Bicuculline methochloride
CAS :<p>(-)-Bicuculline methochloride is a potent antagonist of GABAA receptor.</p>Formule :C21H20ClNO6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :417.84COR659
CAS :<p>COR659: suppresses alcohol/chocolate intake in rats; enhances GABAB receptor, blocks CB1 receptor.</p>Formule :C16H16ClNO3SDegré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :337.82LY 53857
CAS :<p>LY 53857 is a potent and selective antagonist of 5-HT2 serotonin receptor.</p>Formule :C27H36N2O7Couleur et forme :SolidMasse moléculaire :500.592Gentisein
CAS :<p>Gentisein (NSC-329491), a primary metabolite of Mangiferin, exhibits significant inhibition of serotonin uptake, demonstrating potency with an IC50 value of 4.7</p>Formule :C13H8O5Degré de pureté :96.89%Couleur et forme :SolidMasse moléculaire :244.25-HT2 agonist-1 free base
CAS :<p>Compound 24 (5-HT2 agonist-1 free base) is a potent agonist for 5-HT2A, 5-HT2B, and 5-HT2C receptors, exhibiting IC50 values of 10 nM, 8.3 nM, and 1.6 nM,</p>Formule :C19H22N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :310.39P11149
CAS :<p>P11149: oral AChE inhibitor, crosses BBB, IC50 1.3 μM, based on Galanthamine, aims Alzheimer's research.</p>Formule :C27H34ClNO4Couleur et forme :SolidMasse moléculaire :472.02Dothiepin
CAS :<p>Dothiepin (Dosulepin; Dothep), an antidepressant with sedative/anxiolytic properties, preferentially inhibits noradrenaline over serotonin uptake, enhancing</p>Formule :C19H21NSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :295.44Diproqualone
CAS :<p>Diproqualone, analogous to methaqualone, exhibits sedative, anxiolytic, anti-inflammatory, and analgesic properties [1].</p>Formule :C12H14N2O3Couleur et forme :SolidMasse moléculaire :234.255VU6005649
CAS :<p>VU6005649 is an agonist of CNS penetrant mGlu7/8 receptor (EC50s: 0.65 μM and 2.6 μM for mGlu7 receptor and mGlu8 receptor, respectively).</p>Formule :C16H12F5N3ODegré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :357.28AChE-IN-19
CAS :<p>AChE-IN-19: strong AChE blocker (IC50: 0.56 μM), hinders Aβ clumps, neuro-protective, non-toxic to SH-SY5Y, for Alzheimer's research.</p>Formule :C30H33NO7Couleur et forme :SolidMasse moléculaire :519.59Muscarine tosylate
CAS :<p>Muscarine ((+)-Muscarine) tosylate, a prototype mAChR agonist, serves as a parasympathetic nervous system stimulant and is recognized for its toxic properties [1] [2].</p>Formule :C16H27NO5SCouleur et forme :SolidMasse moléculaire :345.45GR 125487 sulfamate
CAS :<p>GR 125487 sulfamate is a 5-HT4 receptor antagonist.</p>Formule :C19H29FN4O8S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :524.58Befiradol
CAS :<p>Befiradol (NLX-112) is an agonist of 5-HT1A receptor.</p>Formule :C20H22ClF2N3OCouleur et forme :SolidMasse moléculaire :393.86PZ-1190
CAS :<p>PZ-1190, a multitarget ligand for serotonin and dopamine receptors, exhibits potential antipsychotic activity in rodents [1].</p>Formule :C27H30N4O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :506.68AAK1-IN-3
CAS :<p>AAK1-IN-3: Brain-penetrant AAK1 inhibitor for neuropathic pain research; IC50=11 nM.</p>Formule :C20H20N4Couleur et forme :SolidMasse moléculaire :316.4mAChR antagonist 1
CAS :<p>Compound 4a, a mAChR antagonist, exhibits K i values of 255 nM for M1 and M5 subtypes, and lower values of 121 nM and 158 nM for M3 and M4 subtypes,</p>Formule :C19H22N2O2Couleur et forme :SolidMasse moléculaire :310.39Mesembrine
CAS :<p>Mesembrine is an alkaloid, a 5-HT transporter inhibitor (K i 1.4 nM), and inhibits PDE4B (IC50 7.8 μM).</p>Formule :C17H23NO3Couleur et forme :SolidMasse moléculaire :289.37MAO-B-IN-1
CAS :<p>MAO-B-IN-1 is a monoamine oxidase B inhibitor and can be used for the research of neurological diseases.</p>Formule :C16H14F3N3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :369.36GYKI-46903 HCl
CAS :<p>GYKI-46903 is a noncompetitive 5-HT3 receptor antagonist.</p>Formule :C17H21ClFNO2Couleur et forme :SolidMasse moléculaire :325.81mGAT3/4-IN-2
CAS :<p>mGAT3/4-IN-2 are potent inhibitors of mGAT3/mGAT4 with their pIC50 values of 5.44 and 5.25, respectively.</p>Formule :C26H32ClN3OS2Couleur et forme :SolidMasse moléculaire :502.13N-Demethyl MK-6884
CAS :<p>N-Demethyl MK-6884 (compound 34) is an M4 mAChR modulator for Alzheimer's and related disease research.</p>Formule :C24H23N5OCouleur et forme :SolidMasse moléculaire :397.47LY3202626
CAS :<p>LY3202626, an amyloid precursor protein secretase (BACE protein) inhibitor, is used for the treatment of Alzheimer's disease.</p>Formule :C22H20F2N8O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :498.51GMA-839
CAS :<p>GMA-839 is a selective modulator of gamma-aminobutyric acid(A) receptors.</p>Formule :C21H31F3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :388.46Nemonapride
CAS :<p>Nemonapride is a dopamine D2-like receptor antagonist.</p>Formule :C21H26ClN3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :387.9Brasofensine sulfate
CAS :<p>Brasofensine sulfate is a dopamine reuptake inhibitor.</p>Formule :C16H22Cl2N2O5SCouleur et forme :SolidMasse moléculaire :425.33rel-HDMP 28 hydrochloride
CAS :<p>Rel-HDMP-28 hydrochloride (Compound 2g) is an analogue of methylphenidate, exhibiting selective affinity for the serotonin transporter (SERT) with a binding constant (Ki) of 105 nM [1].</p>Formule :C18H22ClNO2Couleur et forme :SolidMasse moléculaire :319.83L 663581
CAS :<p>L 663581 is the benzodiazepine receptor partial agonist.</p>Formule :C17H16ClN5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :357.79A-424274
CAS :<p>A-424274 is a positive allosteric modulator of α4β2 neuronal nicotinic receptor.</p>Formule :C14H15N3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :225.29Bisnorcymserine
CAS :<p>Bisnorcymserine reversibly inhibits butyrylcholinesterase, binding Ser(200) and His(440) non-covalently and stacking with Trp(84).</p>Formule :C21H25N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :351.44Cimicoxib
CAS :<p>Cimicoxib (UR8880) is a potent and selective inhibitor of COX-2 with anti-inflammatory and analgesic activity.</p>Formule :C16H13ClFN3O3SDegré de pureté :98.22%Couleur et forme :SolidMasse moléculaire :381.81VU 0255035
CAS :<p>VU 0255035 is a highly selective, competitive and brain penetrant muscarinic M1 receptor antagonist with an IC50 of 130 nM.</p>Formule :C18H20N6O3S2Degré de pureté :98.09% - 98.1%Couleur et forme :SolidMasse moléculaire :432.52JM-1232
CAS :<p>JM-1232 is a sedative and hypnotic drug being researched as a potential anesthetic.</p>Formule :C24H27N3O2Couleur et forme :SolidMasse moléculaire :389.49CGP-54626 free base
CAS :<p>CGP-54626 is a selective antagonist of the GABAB receptor (IC50 = 4 nM ).</p>Formule :C18H28Cl2NO3PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :408.3Capeserod HCl
CAS :<p>Capeserod HCl, a 5-hydroxytriptamine 4 (5-HT4) receptor agonist, is used potentially for the treatment of Alzheimer's disease.</p>Formule :C23H26Cl2N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :493.38Piperidine-4-sulfonic acid
CAS :<p>Piperidine-4-sulfonic acid is a potent GABA agonist, demonstrating an IC50 value of 0.034 μM for the inhibition of H-GABA binding [1].</p>Formule :C5H11NO3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :165.21AChE-IN-30
CAS :<p>AChE-IN-30 is an acetylcholinesterase (AChE) inhibitor exhibiting neuroprotective effects with an inhibitory concentration (IC 50) of 4.4 μM.</p>Formule :C22H24N4O2Couleur et forme :SolidMasse moléculaire :376.45BACE-1 inhibitor 1
CAS :<p>BACE-1 inhibitor 1 (Compound 8a) is an effective BACE-1 inhibitor (IC50: 56 nM).</p>Formule :C17H14BrF3N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :443.22CP-409092
CAS :<p>CP-409092 is a partial GABAA receptor agonist. It has anti-anxiety activity.</p>Formule :C17H19N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :297.35FPPQ
CAS :<p>FPPQ blocks 5-HT3 and 5-HT6 receptors (Ki: 0.9 & 3 nM) and may improve psychosis and cognition.</p>Formule :C21H19FN4O2SCouleur et forme :SolidMasse moléculaire :410.46AAK1-IN-5
CAS :<p>AAK1-IN-5: Potent, selective AAK1 inhibitor; CNS-penetrant; oral; IC50: 1.2 nM; Ki: 0.05 nM; cell IC50: 0.5 nM. Useful in neuropathic pain research.</p>Formule :C19H23F4N3OCouleur et forme :SolidMasse moléculaire :385.4ELND007
CAS :<p>ELND007 is a Gamma secretase inhibitor.</p>Formule :C19H14F4N4O2SCouleur et forme :SolidMasse moléculaire :438.4PTAC oxalate
CAS :<p>muscarinic receptor ligand</p>Formule :C14H21N3O4S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :359.463β-Hydroxy-lup-20(29)-en-16-one
CAS :<p>3β-Hydroxy-lup-20(29)-en-16-one (compound 9) serves as a dual inhibitor of both AChE and BChE, displaying a preference for BChE with an IC50 of 28.9 μM [1].</p>Formule :C30H48O2Couleur et forme :SolidMasse moléculaire :440.7GSM-1
CAS :<p>GSM-1 is a modulator of γ-Secretase.</p>Formule :C26H31ClF3NO2Couleur et forme :SolidMasse moléculaire :481.98Robalzotan
CAS :<p>Robalzotan is a selective 5-HT1A receptor antagonist.</p>Formule :C18H23FN2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :318.39AChE-IN-31
CAS :<p>AChE-IN-31 (compound 1), a non-competitive acetylcholinesterase (AChE) inhibitor, exhibits potential for Alzheimer's disease research [1].</p>Formule :C27H44Na2O9S2Couleur et forme :SolidMasse moléculaire :622.74MK-8768
CAS :<p>MK-8768 is a potent, selective, and orally bioavailable negative allosteric modulator of the mGluR2 class, exhibiting an IC50 of 9.6 nM and characterized by</p>Formule :C21H22F3N5O2Couleur et forme :SolidMasse moléculaire :433.43Osemozotan Free Base
CAS :<p>Osemozotan Free Base is a 5-HT(1A) receptor agonist.</p>Formule :C19H21NO5Couleur et forme :SolidMasse moléculaire :343.37LY2033298
CAS :<p>LY2033298 enhances oximoline's effect on hamster circadian rhythms, aiding neurosystem disorders.</p>Formule :C13H14ClN3O2SDegré de pureté :99.06%Couleur et forme :SolidMasse moléculaire :311.79Brasofensine
CAS :<p>Brasofensine, a benztoalkane MA reuptake inhibitor, shows promise for Parkinson's and Alzheimer's.</p>Formule :C16H20Cl2N2OCouleur et forme :SolidMasse moléculaire :327.25LY108742
CAS :<p>LY108742 is an antagonist of 5-HT2.</p>Formule :C21H28N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :356.46mGluR5 antagonist-1
CAS :<p>mGluR5 antagonist-1 (compound 10) is a potent mGluR5 inhibitor exhibiting an IC50 of 11.5 nM and demonstrates antidepressant effects [1].</p>Formule :C23H18N4O2Couleur et forme :SolidMasse moléculaire :382.41MFZ 10-7
CAS :<p>MFZ 10-7 is anegative allosteric modulator of the mGluR5.</p>Formule :C15H9FN2Degré de pureté :99.80%Couleur et forme :SolidMasse moléculaire :236.24Lanabecestat camsylate
CAS :<p>Lanabecestat camsylate is used as a BACE1 Inhibitor.</p>Formule :C36H44N4O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :644.83GABAA receptor agent 2 TFA
CAS :<p>Potent GABAA antagonist; IC50: 24 nM (α1β2γ2), Ki: 28 nM (rat); inactive on human GABA transporters.</p>Formule :C22H22F3N3O3Couleur et forme :SolidMasse moléculaire :433.42R-96544
CAS :<p>R-96544 is an orally active antagonist of the 5-HT2A receptor that has demonstrated the ability to inhibit platelet aggregation in vitro [1].</p>Formule :C22H30ClNO3Couleur et forme :SolidMasse moléculaire :391.93Cyanopindolol fumarate
CAS :<p>Cyanopindolol fumarate is a 5-HT receptor antagonist [1].</p>Formule :C16H21N3O2C4H4O4Couleur et forme :SolidMasse moléculaire :345.4MIN-117
CAS :<p>MIN-117, a SSRI/5-HT receptor antagonist, is potentially used for the treatment of depression.</p>Formule :C25H26Cl3N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :538.85CAY10649
CAS :<p>1CAY10649, a thiazolinone compound, directly inhibits 5-lipoxygenase (5-LO) product formation in intact polymorphonuclear leukocytes (PMNL) with an IC50 value of 0.28 μM and in a soluble fraction of an S100 PMNL cell lysate with an IC50 value of 0.09 μM, following stimulation by calcium and arachidonic acid. This activity highlights its potential in mitigating inflammatory responses by targeting the biosynthesis of leukotrienes, substances implicated in various inflammatory processes such as neutrophil chemotaxis, increased vascular permeability, and smooth muscle contraction.</p>Formule :C17H12ClNO2SCouleur et forme :SolidMasse moléculaire :329.8AMPA receptor modulator-6
CAS :<p>AMPA receptor modulator-6, an AMPA receptor positive allosteric modulator (PAM), is utilized in the research of neurological diseases [1].</p>Formule :C24H36N2O4S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :480.68NCS-382 sodium
CAS :<p>NCS-382 (sodium) is a potent antagonist of the GABA receptor, exhibiting anti-sedative and anti-hypnotic properties, with applications in neurological disease</p>Formule :C13H13NaO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :240.23NAS181
CAS :<p>rat 5-HT1B receptor antagonist</p>Formule :C21H34N2O10S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :538.63ABT-418 hydrochloride
CAS :<p>ABT-418 HCl enhances cognition and reduces anxiety as a selective nAChRs agonist, researched for Alzheimer's.</p>Formule :C9H15ClN2OCouleur et forme :SolidMasse moléculaire :202.68MAO-IN-3
CAS :<p>MAO-IN-3 (Compound 5), a reversible and competitive monoamine oxidase (MAO) inhibitor with inhibition constants (K i) of 0.6 μM for MAO A and 0.2 μM for MAO B,</p>Formule :C42H54N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :678.9(+)-Bicuculline methiodide
CAS :<p>(+)-Bicuculline methiodide is a GABAA receptor blocker that blocks epileptogens and may be used in the study of neurological disorders.</p>Formule :C21H20INO6Degré de pureté :99.24%Couleur et forme :SolidMasse moléculaire :509.29BACE1-IN-13
CAS :<p>BACE1-IN-13 (Compound 36), an orally active inhibitor of BACE1, exhibits high potency with an IC50 of 2.9 nM and demonstrates greater efficacy in hAβ42 cells (</p>Formule :C20H17FN8O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :420.45-HT2A antagonist 1
CAS :<p>5-HT2A antagonist 1, from US5728835A & JP 1007727, may treat gastrointestinal and circulatory issues.</p>Formule :C26H28N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :428.53Indeloxazine hydrochloride
CAS :<p>Indeloxazine HCl: Serotonin releaser, NE reuptake inhibitor, NMDA antagonist; antidepressant that boosts acetylcholine in rats.</p>Formule :C14H18ClNO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :267.75MAO-B-IN-19
CAS :<p>MAO-B-IN-19, a selective MAO-B inhibitor, exhibits neuroprotective and anti-inflammatory properties and demonstrates an IC50 value of 0.67 μM [1].</p>Formule :C15H11FO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :242.25FPTQ
CAS :<p>FPTQ is a highly effective antagonist of mGluR 1, displaying IC50 values of 6 nM and 1.4 nM for human and mouse mGluR1 respectively [1].</p>Formule :C17H12FN5Degré de pureté :99.68% - 99.88%Couleur et forme :SolidMasse moléculaire :305.31Velusetrag
CAS :<p>Velusetrag(TD-5108), a potent 5-HT4 agonist, is in development for gastroparesis, constipation, and IBS.</p>Formule :C25H36N4O5SCouleur et forme :SolidMasse moléculaire :504.64Facinicline hydrochloride
CAS :<p>Facinicline hydrochloride (RG3487) is both a novel nicotinic alpha-7 receptor (alpha7nAChR) partial agonist (Ki = 6 nM) and an antagonist of 5-HT3(Ki = 1.2 nM).</p>Formule :C15H19ClN4ODegré de pureté :98.70%Couleur et forme :SolidMasse moléculaire :306.795-HT3 antagonist 1
CAS :<p>5-HT3 antagonist 1 is a potent and selective antagonist of 5-HT3 receptor.</p>Formule :C22H27N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :377.482-Methyl-5-HT
CAS :<p>2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.</p>Formule :C11H14N2ODegré de pureté :97.18%Couleur et forme :SolidMasse moléculaire :190.24SCS
CAS :<p>SCS is a GABAA receptor antagonist.</p>Formule :C14H12N2O3Degré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :256.26NO-711ME
CAS :<p>NO-711ME (N-O711 Methyl ester) is a prodrug of NO-711. It also is a potent and selective GABA uptake inhibitor.</p>Formule :C22H24N2O3Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :364.44JNJ-46281222
CAS :<p>JNJ-46281222: mGlu2-selective, potent PAM, Kd = 1.7 nM, pEC50 = 7.71.</p>Formule :C23H25F3N4Couleur et forme :SolidMasse moléculaire :414.47L-772,405
CAS :<p>L-772,405 is a highly selective agonists of h5-HT(1D) receptor.</p>Formule :C26H31FN6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :462.56ADX71441
CAS :<p>ADX71441, a GABAB PAM, lengthens urinary latencies, lessens events & volume, and may aid in alcoholism and bladder pain.</p>Formule :C19H15ClF2N4O4Couleur et forme :SolidMasse moléculaire :436.8Adipiplon
CAS :<p>Adipiplon(NG2-73, NG273) is a novel selective gamma-aminobutyric acid (GABA) partial agonist.</p>Formule :C18H18FN7Couleur et forme :SolidMasse moléculaire :351.38Adenylyl cyclase-IN-1
CAS :<p>Adenylyl cyclase-IN-1 is a potential adenylyl cyclase inhibitor for ocular hypotonia research [1].</p>Formule :C9H8N2S3Couleur et forme :SolidMasse moléculaire :240.37Flesinoxan
CAS :<p>Flesinoxan is a hypotensive agent and is an effective, high affinity, and selective 5-hydroxytryptamine1A receptor agonist (EC50: 24 nM).</p>Formule :C22H26FN3O4Couleur et forme :SolidMasse moléculaire :415.46U 89843A
CAS :<p>U 89843A is a positive allosteric modulator of gamma-aminobutyric acid (GABA)A receptors.</p>Formule :C16H23N5Degré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :285.39YM348
CAS :<p>YM348 is an effective and orally active 5-HT2C receptor agonist. YM348 also shows a high affinity for the cloned human 5-HT2C receptor (Ki: 0.89 nM).</p>Formule :C14H17N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :243.3P2X3 antagonist 38
CAS :<p>Compound 38, also known as Compound 4, is a potent, orally active P2X3 antagonist that demonstrates inhibitory activity with IC50 values of 0.132 µM, 0.165 µM,</p>Formule :C22H25F3N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :478.47Thioflosulide
CAS :<p>Thioflosulide (L-745337) is a selective and potent COX2 inhibitor (IC50: 2.3 nM) with anti-inflammatory activity for the study of gastric ulcers.</p>Formule :C16H13F2NO3S2Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :369.41VU6012962
CAS :<p>VU6012962 is an orally bioavailable negative allosteric modulator of CNS-penetrant metabotropic glutamate receptor 7(mGlu7; IC50: 347 nM).</p>Formule :C21H19F3N4O4Degré de pureté :99.61% - 99.74%Couleur et forme :SolidMasse moléculaire :448.4C3
CAS :<p>C3 functions as a selective inhibitor of monoamine oxidase B (MAO-B; IC50= 0.021 µM), demonstrating preference over monoamine oxidase A (MAO-A; IC50= 26.8 µM). This compound, at dosages of 0.1, 1, and 3 mg/kg, effectively counters MPTP-induced reductions in dopamine levels within the mouse brain.</p>Formule :C18H19FN2O2Couleur et forme :SolidMasse moléculaire :314.35PQM130
CAS :<p>PQM130 is a Feruloyl-Donepezil Hybrid compound against the neurotoxicity induced by Aβ1-42 oligomer (AβO) and shows anti-inflammatory activity.</p>Formule :C23H27NO4Degré de pureté :98.73%Couleur et forme :SolidMasse moléculaire :381.46Physostigmine hemisulfate
CAS :<p>cholinesterase inhibitor</p>Formule :C15H21N302H204SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :324.39CGP 64213
CAS :<p>CGP 64213 is a GABAb receptor agonist.</p>Formule :C26H36IN2O7PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :646.45Naspm trihydrochloride
CAS :<p>Naspm trihydrochloride (1-Naphthylacetyl spermine trihydrochloride) is a synthetic analogue of Joro spider toxin and is an antagonist of calcium permeable AMPA</p>Formule :C22H37Cl3N4ODegré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :479.91(S)-Bexicaserin
CAS :<p>(S)-Bexcaserin (compound 2) serves as a 5-HT2C receptor agonist, presenting research possibilities in obesity and psychiatric disorders [1].</p>Formule :C15H19F2N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :295.33LY320954
CAS :<p>LY320954 is an antagonist of 5-HT2A receptor.</p>Formule :C21H26N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :382.46Quinolactacin A1
CAS :<p>Quinolactacin A1, a strong AChE inhibitor from Penicillium citrinum, aids Alzheimer's research.</p>Formule :C16H18N2O2Couleur et forme :SolidMasse moléculaire :270.33Calmidazolium chloride
CAS :<p>Calmidazolium chloride blocks calmodulin, hinders phosphodiesterase (IC50=0.15µM), Ca2+-ATPase (IC50=0.35µM), and can induce cancer cell apoptosis.</p>Formule :C31H23Cl7N2ODegré de pureté :98.53%Couleur et forme :SolidMasse moléculaire :687.7Pregnanolone sulfate (pyridinium)
CAS :<p>Pregnanolone sulfate pyridinium, an endogenous neurosteroid, inhibits NMDA receptors and exhibits neuroprotective properties [1].</p>Formule :C26H39NO5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :477.66
