Neuroscience
Les inhibiteurs en neurosciences sont des composés conçus pour moduler l'activité de protéines, d'enzymes ou de récepteurs spécifiques au sein du système nerveux. Ces inhibiteurs sont cruciaux pour étudier les mécanismes moléculaires sous-jacents au fonctionnement neuronal, à la transmission synaptique et aux maladies neurodégénératives. En ciblant les récepteurs des neurotransmetteurs, les canaux ioniques et les voies de signalisation, les inhibiteurs en neurosciences facilitent l'exploration du fonctionnement cérébral et le développement de stratégies thérapeutiques pour des troubles neurologiques tels que la maladie d'Alzheimer, de Parkinson et l'épilepsie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs en neurosciences de haute qualité pour soutenir vos recherches en neurobiologie, neuropharmacologie et sciences cognitives.
Sous-catégories appartenant à la catégorie "Neuroscience"
- récepteur 5-HT(940 produits)
- ACK(1 produits)
- AChR(574 produits)
- ATP Citrate Lyase(16 produits)
- Récepteur adrénergique(2.939 produits)
- BACE(36 produits)
- Bêta-amyloïde(204 produits)
- CaMK(68 produits)
- COX(562 produits)
- Récepteur de la dopamine(407 produits)
- Récepteur GABA(336 produits)
- Gamma-sécrétase(59 produits)
- GluR(255 produits)
- GlyT(24 produits)
- Récepteur de l'histamine(358 produits)
- LRRK2(33 produits)
- Récepteur de la mélatonine(24 produits)
- NMDAR(28 produits)
- Récepteur OX(40 produits)
- Récepteur opioïde(296 produits)
Affichez 12 plus de sous-catégories
5400 produits trouvés pour "Neuroscience"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
[Ala11,D-Leu15]-Orexin B acetate
<p>[Ala11,D-Leu15]-Orexin B acetate is a selective agonist of orexin-2 receptor (OX2) with an EC50 of 0.13 nM, showing 400-fold selectivity over OX1 (52 nM).</p>Formule :C122H210N44O37SDegré de pureté :98.18%Couleur et forme :SolidMasse moléculaire :2917.31TC-2216
CAS :<p>TC-2216 is a partial agonist at the neural nicotinic acetylcholine receptor and is used to treat anxiety and depression.</p>Formule :C12H17N3Degré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :203.28TET-13
<p>TET-13 is a positive allosteric modulator of the GABAA receptor with an EC50 of 5.65 μM, which is more potent than Etomidate (EC50: 9.29 μM). It exhibits strong anesthetic effects in both mice and rats, with an ED50 of 0.48 mg/kg in mice and 0.69 mg/kg in rats.</p>Formule :C15H16N2O3SCouleur et forme :SolidMasse moléculaire :304.36N-Desmethyl Pimavanserin
CAS :<p>N-Desmethyl Pimavanserin (AC-279) is the active metabolite of Pimavanserin and is used in the treatment of insomnia and other sleep disorders.</p>Formule :C24H32FN3O2Degré de pureté :98.02%Couleur et forme :SolidMasse moléculaire :413.53p-Xylene bis(pyridinium bromide)
CAS :<p>p-Xylene bis(pyridinium bromide) (compound 21) is a cationic quenching agent and acts as a weak bis-quaternary ammonium salt inhibitor for AChE and BChE, with IC50 values of 1540 μM and 529 μM, respectively.</p>Formule :C18H18Br2N2Couleur et forme :SolidMasse moléculaire :422.16Sabirnetug
CAS :<p>Sabirnetug is a humanized IgG2κ monoclonal antibody that specifically targets the amyloid-β (A4) precursor protein.</p>Couleur et forme :LiquidOrg 13011
CAS :<p>Org 13011 has CNS activity and induces conditioned taste aversion by mediating 5-HT 1A receptors.</p>Formule :C18H25F3N4ODegré de pureté :98.02%Couleur et forme :SoildMasse moléculaire :370.41SKF-83566 hydrochloride
CAS :<p>SKF-83566 hydrochloride is a D1-like dopamine receptor antagonist, inhibiting dopamine transporters and mitigating GBP-induced CPP.</p>Formule :C17H19BrClNODegré de pureté :99.27%Couleur et forme :SoildMasse moléculaire :368.69Cinazepam
CAS :<p>Cinazepam is a GABAA receptor partial agonist and a benzodiazepine derivative with anxiolytic and sedative properties. Cinazepam can be utilized in research related to sleep disorders.</p>Formule :C19H14BrClN2O5Couleur et forme :SolidMasse moléculaire :465.68DOPR hydrochloride
CAS :<p>DOPR hydrochloride is a psychoactive substance belonging to the amphetamine class.</p>Formule :C14H24ClNO2Couleur et forme :SolidMasse moléculaire :273.8Femoxetine
CAS :<p>Femoxetine: antidepressant, enhances morphine, inhibits MAO-A/B, boosts mice's exercise capacity.</p>Formule :C20H25NO2Degré de pureté :99.1% - 99.35%Couleur et forme :SolidMasse moléculaire :311.42SQ-3
<p>SQ-3, a quinoline analogue, prefers α-syn (Ki=39.3nM) to Aβ (Ki=230nM), and [18F]SQ3 is a lead for α-syn probes. [1]</p>Formule :C21H21FN2OCouleur et forme :SolidMasse moléculaire :336.4Tryptamine hydrochloride
CAS :<p>Tryptamine hydrochloride is a monoamine alkaloid, metabolite of tryptophan and CNS active substance, agonist of 5-HT4 receptor, TAAR1, AHR.</p>Formule :C10H13ClN2Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :196.68rac Desmethyl Citalopram Hydrochloride
CAS :<p>rac Desmethyl Citalopram Hydrochloride is a 5-hydroxy tryptamine uptake inhibitor with IC50 value of 0.013 μM.</p>Formule :C19H20ClFN2ODegré de pureté :99.24%Couleur et forme :SolidMasse moléculaire :346.83(Iso)-Landipirdine
CAS :<p>(Iso)-Landipirdine((Iso)-RO5025181) is a selective and potent 5-HT6R antagonist.</p>Formule :C18H19FN2O3SDegré de pureté :98.50%Couleur et forme :SoildMasse moléculaire :362.42Dalidnetug
CAS :<p>Dalidnetug is a humanized monoclonal antibody that targets human β-amyloid precursor protein (APP). By specifically binding to APP, Dalidnetug reduces the production of β-amyloid (Aβ), thereby demonstrating activity in clearing β-amyloid. This compound holds potential for research in Alzheimer's disease.</p>Couleur et forme :Liquid4-Bromo-2,5-DMMA
CAS :<p>4-Bromo-2,5-DMMA (Compound 2) demonstrates affinity for the 5-HT2 binding site and has an ED50 of 0.82 mg/kg in rat discrimination experiments.</p>Formule :C12H18BrNO2Couleur et forme :SolidMasse moléculaire :288.18Emamectin B1a
CAS :<p>Emamectin B1a can be used in relevant research in the life sciences. Its product number is T37663 and CAS number is 121124-29-6.</p>Formule :C49H75NO13Couleur et forme :SolidMasse moléculaire :886.133Binospirone
CAS :<p>Binospirone (MDL 73005EF) is a 5-HT1A receptor agonist with anxiolytic activity used in the study of movement disorders associated with neurologic dysfunction.</p>Formule :C20H26N2O4Degré de pureté :97.57% - 98.96%Couleur et forme :SoildMasse moléculaire :358.43GRGDSPK acetate
CAS :<p>GRGDSPK acetate shows inhibitory activity against integrin-fibronectin binding and can be used in research on integrins in bone formation and resorption.</p>Formule :C30H53N11O13Degré de pureté :97.9%Couleur et forme :SoildMasse moléculaire :775.81hAChE/hBuChE/GSK-3β-IN-1
<p>hAChE/hBuChE/GSK-3β-IN-1 (Compound 6c) is a multi-target compound designed for Alzheimer's treatment capable of crossing the blood-brain barrier. It inhibits hAChE with an IC50 of 28.88 nM, hBuChE with an IC50 of 131.90 nM, and GSK-3β with an IC50 of 51.42 nM. Additionally, it acts as an inhibitor of tau protein and Aβ protein aggregation.</p>Formule :C19H15NO4Couleur et forme :SolidMasse moléculaire :321.327Desalkylgidazepam
CAS :<p>Desalkylgidazepam, a benzodiazepine compound, is a metabolite of gidazepam. It is capable of activating both GABA A-type receptors and the translocator protein (TSPO).</p>Formule :C15H11BrN2OCouleur et forme :SolidMasse moléculaire :315.1725N-NBOMe hydrochloride
CAS :<p>25N-NBOMe hydrochloride is a derivative of 2C-N and acts as an agonist for the 5-HT2A and 5-HT2C receptors, with Ki values of 0.144 nM and 1.06 nM, respectively. It has minimal effect on the release of preloaded neurotransmitters from recombinant dopamine, serotonin, and norepinephrine transporters.</p>Formule :C18H23ClN2O5Couleur et forme :SolidMasse moléculaire :382.84Bis-(-)-8-demethylmaritidine
<p>Bis-(-)-8-demethylmaritidine, a natural alkaloid, serves as a potent inhibitor of acetylcholinesterase (AChE) and is utilized in Alzheimer's disease research [1</p>Couleur et forme :Odour SolidTetrahydro-β-carboline
CAS :<p>Compound Fr12161, with CAS No. 16502-01-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr12161 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Formule :C11H12N2Degré de pureté :96.31%Couleur et forme :Tan SolidMasse moléculaire :172.2264LPYFD-NH2
CAS :<p>neuroprotective peptide that binds to amyloid beta (Aβ)</p>Formule :C33H44N6O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :652.74(S)-Vamicamide
CAS :<p>(S)-Vamicamide is an anti-anticholinergic compound.</p>Formule :C18H23N3ODegré de pureté :99.48% - 99.65%Couleur et forme :SoildMasse moléculaire :297.39β-Amyloid (4-10)
CAS :<p>Antibodies corresponding to beta-amyloid (4-10) are effective in vivo inhibitors of cytotoxicity, amyloid plaque formation and special memory disturbances in</p>Formule :C39H52N12O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :880.95-MeO-MET
CAS :<p>5-MeO-MET (5-Methoxy-N-methyl-N-ethyltryptamine) is a compound belonging to the 5-methoxytryptamine class. It acts as an agonist for 5-HT1A and 5-HT2A receptors. In mice, 5-MeO-MET inhibits locomotion and has sedative effects.</p>Formule :C14H20N2OCouleur et forme :SolidMasse moléculaire :232.32GABA-A Receptor Ligand-1
<p>GABA-A Receptor Ligand-1 (Compound 4) is a ligand for the GABA-A receptor with a pKi of 7.27. It alleviates mitochondrial dysfunction, promotes neurite outgrowth and neuronal regeneration, and demonstrates neuroprotective effects in a rat ischemic stroke model.</p>Formule :C20H20FN3OCouleur et forme :SolidMasse moléculaire :337.391Orexin A (human, rat, mouse) acetate
<p>Orexin A (human, rat, mouse) acetate (Hypocretin-1 (human, rat, mouse) acetate) is an excitatory neuropeptide with analgesic properties.</p>Formule :C154H247N47O46S4Couleur et forme :SolidMasse moléculaire :3621.15Withasomniferolide B
CAS :<p>Withasomniferolide B, a withanolide from Withania somnifera root, activates GABAA receptors.</p>Formule :C28H36O4Couleur et forme :SolidMasse moléculaire :436.583-Hydroxy desalkylflurazepam
CAS :<p>3-Hydroxy desalkylflurazepam is a benzodiazepine compound with potential sedative and anxiolytic effects.</p>Formule :C15H10ClFN2O2Couleur et forme :SolidMasse moléculaire :304.7Antidepressant agent 3
<p>Agent 3: orally active, antidepressant, anxiolytic, boosts performance and cognition.</p>Formule :C17H30ClN5O2SCouleur et forme :SolidMasse moléculaire :403.97β-Amyloid (1-20)
CAS :<p>This synthetic peptide consists of amino acids 1 to 20 of beta amyloid protein.</p>Formule :C113H157N31O32Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2461.7Fasciculic acid B
CAS :<p>Fasciculic acid B: ester of fasciculol B, 3-hydroxy-methylglutaric acid; a calmodulin antagonist from Naematoloma fasciculare.</p>Formule :C36H60O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :636.86RS 56812
CAS :<p>RS 56812 is a 5-HT3 receptor antagonist and agonist used in the study of cognitive disorders.</p>Formule :C18H21N3O2Degré de pureté :99.38%Couleur et forme :SoildMasse moléculaire :311.387-Methyl DMT
CAS :<p>7-Methyl DMT (7-TMT) acts as a 5-HT2 receptor agonist. Structurally, it is a tryptamine derivative and serves as an analytical reference for the psychoactive substance DOM. It is also applicable in research related to neurological disorders.</p>Formule :C13H18N2Couleur et forme :SolidMasse moléculaire :202.3GM-60186
<p>GM-60186, a potent inhibitor of the 5-HT receptor 2B (HTR2B) with an IC50 of 257 nM, effectively suppresses the proliferation and migration of colorectal cancer cells.</p>Formule :C30H33FN2O4Couleur et forme :SolidMasse moléculaire :504.59AMI-193
CAS :<p>AMI-193 (Spiramide) is a selective 5-HT2 & D2 receptor antagonist with antipsychotic properties.</p>Formule :C22H26FN3O2Degré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :383.462,3-Dehydrosilybin A
CAS :<p>2,3-Dehydrosilybin A is a useful organic compound for research related to life sciences and the catalog number is T125202.</p>Formule :C25H20O10Couleur et forme :SolidMasse moléculaire :480.425Dapoxetine
CAS :<p>Dapoxetine (Dapoxetina) is a selective serotonin reuptake inhibitor, for the treatment of premature ejaculation.</p>Formule :C21H23NODegré de pureté :99.73%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :305.42Perlapine
CAS :<p>Perlapine is an effective and selective HM3DQ DREADD agonist (EC50 = 2.8 nM).</p>Formule :C19H21N3Couleur et forme :SolidMasse moléculaire :291.39Tiaspirone hydrochloride
CAS :<p>Tiaspirone hydrochloride (BMY-13859 hydrochloride) exhibits antipsychotic activity and influences the electrophysiological activity of dopaminergic neurons.</p>Formule :C24H33ClN4O2SDegré de pureté :99.87%Couleur et forme :SoildMasse moléculaire :477.06AChE-IN-60
<p>AChE-IN-60 (compound 6k) is a potent inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), with IC50 values of 27 nM and 43 nM, respectively. It also inhibits monoamine oxidase MAO-A and MAO-B, with IC50 values of 353 nM and 716 nM, respectively.</p>Formule :C24H29N3O4S3Masse moléculaire :519.13202Oxotremorine
CAS :<p>Oxotremorine acts as an agonist of mAChR, specifically activating the M1 and M3 acetylcholine receptors. In drug discrimination experiments with macaques, it exhibits effects similar to nicotine.</p>Formule :C12H18N2OCouleur et forme :SolidMasse moléculaire :206.28(R)-Citalopram oxalate
CAS :<p>(R)-Citalopram oxalate is a weak selective serotonin reuptake inhibitor (SSRI) that antagonises its S-isomer (escitalopram), anticonvulsant and antidepressant</p>Formule :C22H23FN2O5Degré de pureté :99.76%Couleur et forme :White SolidMasse moléculaire :414.43FITC-β-Ala-Amyloid β-Protein (1-42)
CAS :<p>FITC-β-Ala-Amyloid β-Protein (1-42) is a polypeptide identified through peptide screening. This screening method predominantly utilizes immunoassays to gather active polypeptides and is used in studying protein interactions, conducting functional analyses, and screening antigen epitopes, with particular application in the research and development of active molecules.</p>Formule :C227H327N57O66S2Masse moléculaire :4971.34251LE 300
CAS :<p>LE 300 represents a structurally novel type of antagonists acting preferentially at the dopamine D(1)/D(5)receptors and the serotonin 5-HT(2A)receptor.</p>Formule :C20H22N2Degré de pureté :97.91% - 98.79%Couleur et forme :SolidMasse moléculaire :290.4Octamylamine
CAS :<p>Octamylamine is a bioactive chemical.</p>Formule :C13H29NCouleur et forme :SolidMasse moléculaire :199.37615-HT6R antagonist 6
<p>5-HT6R antagonist 6 (Compound PP15) exhibits high affinity and selectivity for the 5-HT6R receptor, with a Ki of 42 nM. It demonstrates weak antiproliferative activity on tumor cells and low toxicity toward normal cells. 5-HT6R antagonist 6 is applicable in tumor research.</p>Formule :C24H26N4O2SCouleur et forme :SolidMasse moléculaire :434.55LOX-IN-4
CAS :<p>LOX-IN-4 (Compound 112) is an inhibitor of lysyl oxidase (LOX). It holds potential for use in cancer research.</p>Formule :C20H24Cl2FN3O2SCouleur et forme :SolidMasse moléculaire :460.39Aβ1-14-εK-KKK-MvF5 Th
<p>Aβ1-14-εK-KKK-MvF5 Th (UB311 immunogen I) is a biologically active peptide and one of the Aβ1–14 targeting peptides (B-cell epitope) used in UB-311.</p>Formule :C199H318N56O55Masse moléculaire :4372.38081Rilmazolam
CAS :<p>Rilmazolam is a triazolobenzodiazepine compound and serves as the active metabolite of Rilmazafone.</p>Formule :C19H15Cl2N5OCouleur et forme :SolidMasse moléculaire :400.26Melatonin-Tamoxifen Conjugate
<p>Melatonin-Tamoxifen Conjugate (compound 16c) is an anticancer drug conjugate made of Melatonin and Tamoxifen, serving as an effective antagonist of ERα (IC50 = 863 nM). In cells expressing the hMT1 receptor, it binds to MLT receptors (Ki = 3.1 nM) and exhibits the ability to promote β-arrestin activation (EC50 = 914 nM) and ERK activation (EC50 = 98 nM). The IC50 values for Melatonin-Tamoxifen Conjugate in MCF-7, MDA-MB-231, and HT-1080 cell lines are 6.8 μM, 6.4 μM, and 1.7 μM, respectively.</p>Formule :C47H58N4O4Couleur et forme :SolidMasse moléculaire :742.99β-Amyloid (12-20)
CAS :<p>β-Amyloid (12-20) is a peptide fragment of β-Amyloid.Thsis peptide contain the amino acid residues VFF at position (18-20), suggesting that this triad has</p>Formule :C57H83N15O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1154.36Brexanolone caprilcerbate
CAS :<p>Brexanolone caprilcerbate is an effective positive allosteric modulator of the GABAA receptor.</p>Formule :C48H78O12Couleur et forme :SolidMasse moléculaire :847.13β-Secretase inhibitor-STA
CAS :<p>BACE-IN-1 is amyloid precursor protein beta-secretase inhibitor</p>Formule :C73H118N16O27Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1651.81Tiquizium
CAS :<p>Tiquizium has effective Antimuscarinic effect, and causes significant bronchodilation in patients with chronic obstructive pulmonary disease.</p>Formule :C19H24NS2Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :330.53(S)-AMPA HCl
<p>(S)-AMPA HCl (L-AMPA HCl) is a selective AMPA receptor agonist with potential antidepressant activity. It can be used in research on Parkinson's disease.</p>Formule :C7H11ClN2O4Degré de pureté :99.18%Couleur et forme :SolidMasse moléculaire :222.63nAChR modulator-2
CAS :<p>nAChR modulator-2, a insecticide, is a insect nAChR orthosteric modulator [1] .</p>Formule :C12H8ClN3O2Couleur et forme :SolidMasse moléculaire :261.66AC3-I, myristoylated
<p>Myristoylated AC3-I is a biologically active peptide and a myristoylated variant of the Autocamtide-3-Derived Inhibitory Peptide (AC3-I).</p>Formule :C78H137N21O20Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1689.05M4 mAChR agonist-1
CAS :<p>M4 mAChR agonist-1 (4-Piperidinecarboxamide, 1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)-) is an effective agonist of M4 mAChR (EC50 >10 μM).</p>Formule :C14H18N4OSDegré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :290.38RuBi-Nicotine
CAS :<p>Nicotinic receptor agonist</p>Formule :C40H44Cl2N8RuDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :808.81Guvacine hydrobromide
CAS :<p>Guvacine hydrobromide, an alkaloid derived from the Areca catechu nut, serves as a potent inhibitor of GABA (GABA uptakp) uptake.</p>Formule :C6H10BrNO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :208.05Davunetide acetate
<p>Davunetide acetate is derived from activity-dependent neuroprotective protein existing in the mammalian CNS.</p>Formule :C38H64N10O14Degré de pureté :99.52% - 99.78%Couleur et forme :SolidMasse moléculaire :884.97Malaoxon
CAS :<p>Malaoxon is used as an insecticide.</p>Formule :C10H19O7PSCouleur et forme :SolidMasse moléculaire :314.29MmTx1 toxin
<p>Micrurotoxin 1 (MmTx1 toxin) acts as an allosteric modulator of GABA A receptors, enhancing the receptor's sensitivity to its agonist [1].</p>Formule :C295H455N95O97S10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :7205CaMKIIα-PHOTAC
<p>CaMKIIα-PHOTAC is a photochemically targeted chimera (PHOTAC) that specifically targets Ca2+/calmodulin-dependent protein kinase II α (CaMKIIα).</p>Formule :C54H58Cl2N10O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1094GAD65(247-266) epitope TFA
<p>GAD65(247-266) epitope TFA, a T cell epitope derived from islet antigens, exhibits competitive binding to the type I diabetes-associated molecule I-A g7, albeit</p>Formule :C111H174F3N27O29S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2535.99COX-1/2-IN-5
<p>COX-1/2-IN-5 (compound 2a) functions as a dual inhibitor of COX1/2, demonstrating inhibitory concentrations (IC50) of 2.650 μM and 0.958 μM, respectively, and</p>Formule :C21H22N2O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :414.47IHC3
<p>IHC3 is a competitive and reversible monoamine oxidase B (MAO-B) inhibitor with an IC50 of 1.672 μM, which targets Cys172 within the enzyme's active site.</p>Formule :C17H12FN3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :293.3MAOA-IN-1
<p>MAOA-IN-1 (compound 15) is an orally-active inhibitor of monoamine oxidase A (MAOA) that exhibits cytotoxic effects on prostate cancer cells.</p>Formule :C13H16Cl2N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :303.18NNC 11-1607
CAS :<p>NNC 11-1607 is a functionally selective agonist of M(1)/M(4) mAChR.</p>Formule :C30H32N6O2S2Couleur et forme :SolidMasse moléculaire :572.74Rapastinel acetate
CAS :<p>Rapastinel acetate is a modulator of N-methyl-D-aspartate (NMDA) receptor and a partial agonist of glycine site long-lasting antidepressant effects.</p>Formule :C20H35N5O8Degré de pureté :99.6%Couleur et forme :SoildMasse moléculaire :473.52GABA receptor Antagonist 1
<p>GABA receptor Antagonist 1 (compound 7w) effectively inhibits the Px RDL1 GABAR at an IC50 of 7.08 nmol/L and demonstrates insecticidal efficacy against P.</p>Degré de pureté :98%Couleur et forme :Odour SolidMmTx2 toxin
<p>MmTx2 toxin, extracted from the venom of the coral snake, serves as a modulator of the GABA A receptor, increasing its responsiveness to agonists.</p>Formule :C295H450N94O97S10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :7185.95Lysyl hydroxylase 2-IN-2
<p>Lysyl Hydroxylase 2-IN-2 (compound 13) is a potent inhibitor of Lysyl Hydroxylase 2 (LH2), exhibiting an IC50 of approximately 500 nM.</p>Formule :C19H21N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :323.39NMDA receptor antagonist 6
<p>NMDA Receptor Antagonist 6 (Compound 13b) functions as an antagonist at the glycine-binding site of the NMDA receptor and demonstrates cytoneuroprotective</p>Formule :C25H23NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :369.462-APB hydrochloride
CAS :<p>2-APB is an analog of 6-APB and falls under the category of benzofuran derivatives, known for its psychoactive properties. Certain benzofuran derivatives also exhibit monoamine oxidase-A (MAO-A) inhibitory activity.</p>Formule :C11H14ClNOCouleur et forme :SolidMasse moléculaire :211.69AChE/MAO-B-IN-7
<p>AChE/MAO-B-IN-7 (VAV-8) is a compound that acts as a dual inhibitor of acetylcholinesterase (AChE) and MAO-B, with the ability to cross the blood-brain barrier. It also inhibits the aggregation of Aβ42, making it a valuable compound for Alzheimer's disease (AD) research.</p>Formule :C22H21N3O3Couleur et forme :SolidMasse moléculaire :375.42Methalthiazide
CAS :<p>Methalthiazide enhances the activity of natural agonists of AMPA receptors and can be utilized in schizophrenia research.</p>Formule :C12H16ClN3O4S3Couleur et forme :SolidMasse moléculaire :397.925-AAM-2-CP
CAS :<p>5-AAM-2-CP is one of the major metabolites of Acetamiprid. Acetamiprid, a nAChR agonist, is a neonicotinoid insecticide used worldwide.</p>Formule :C8H9ClN2ODegré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :184.62(S)-3,4-DCPG HCl
<p>(S)-3,4-DCPG HCl is a selective mGluR8a agonist, impacting AV12-664 cells with an EC50 of 31 nM.</p>Formule :C10H10ClNO6Degré de pureté :99.53% - 99.9%Couleur et forme :SoildMasse moléculaire :275.64PSEN1-IN-1
<p>PSEN1-IN-1 (Compound (+)-13b) functions as an inhibitor of PSEN1, displaying potent inhibition of the PSEN1-APH1A and PSEN1-APH1B complexes with respective IC50</p>Formule :C20H19ClF3NO3SCouleur et forme :SolidMasse moléculaire :445.88HTR2A antagonist 1
<p>HTR2A antagonist 1 (Compound 15f) is an HTR2A antagonist with an IC50 of 42.79 nM. It induces sub-G1 cell cycle arrest and apoptosis in colorectal cancer cells by activating the p53/p21/caspase 3 signaling pathway. HTR2A antagonist 1 exhibits good liver microsomal stability and is useful for colorectal cancer research.</p>Formule :C35H43Cl2F2N5O4Couleur et forme :SolidMasse moléculaire :706.65Imagabalin
CAS :<p>Imagabalin is an active compound used in the study of neurological diseases.</p>Formule :C9H19NO2Couleur et forme :SolidMasse moléculaire :173.25JF-NP-26
<p>Releases pain-blocking raseglurant under 405 nm light. Inhibits Quisqualate. Analgesic in vivo. Quantum yield: 0.18.</p>Couleur et forme :SolidMMPIP hydrochloride
CAS :<p>MMPIP hydrochloride is a selective antagonist of allosteric mGluR7.</p>Formule :C19H16ClN3O3Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :369.8β-Amyloid (1-9)
CAS :<p>This is an N-terminal fragment of beta amyloid.</p>Formule :C42H60N14O17Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1033.01LY 293284
CAS :<p>LY 293284 is a potent, selective full agonist of 5-HT1A receptor with anxiogenic effects in animal studies.</p>Formule :C19H26N2OCouleur et forme :SolidMasse moléculaire :298.42(+)-Coclaurine hydrochloride
CAS :<p>(+)-Coclaurine hydrochloride, also known as (+)-(R)-Coclaurine, is a benzyltetrahydroisoquinoline alkaloid extracted from multiple plant species.</p>Formule :C17H20ClNO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :321.8LY3020371
CAS :<p>LY3020371: potent, selective mGlu 2/3 receptor antagonist with Ki of 5.26 nM (hmGluR2) and 2.50 nM (hmGluR3); key in depression studies.</p>Formule :C15H15F2NO5SCouleur et forme :SolidMasse moléculaire :359.34(-)-Eseroline fumarate
CAS :<p>(-)-Eseroline fumarate, a Physostigmine metabolite and AChE inhibitor, triggers cancer cell LDH release and neuronal cell death.</p>Formule :C17H22N2O5Couleur et forme :SolidMasse moléculaire :334.37ACHE Inhibitor 12
CAS :<p>ACHE Inhibitor 12 inhibited acetylcholinesterase with an IC50 value of 0.38 µM.</p>Formule :C11H12ODegré de pureté :98.71%Couleur et forme :SolidMasse moléculaire :160.21Ro60-0175
CAS :<p>Ro60-0175 is a selective 5-HT2B and 5-HT2C serotonin receptor agonist, often used as fumarate.</p>Formule :C11H12ClFN2Degré de pureté :97.09%Couleur et forme :SolidMasse moléculaire :226.68FGIN-1-43
CAS :<p>FGIN-1-43 is a potent and specific ligand for the mitochondrial DBI receptor.</p>Formule :C28H36Cl2N2ODegré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :487.5AChE-IN-43
<p>AChE-IN-43 is a potent, selective AChE inhibitor with a K i of 0.41 μM, applicable in the study of neurological diseases [1].</p>Couleur et forme :Odour Solid(Iso)-Atagabalin HCl
CAS :<p>(Iso)-Atagabalin HCl(isomer-Atagabalin HCl) is an alpha -2- delta ligand that can be used to treat non-restorative sleep.</p>Formule :C10H20ClNO2Degré de pureté :99.26% - >99.99%Couleur et forme :SoildMasse moléculaire :221.72Cabergoline
CAS :<p>Cabergoline (FCE-21336), an ergot-derived dopamine D2-like agonist, targets D2/D3/5-HT2B, normalizes prolactin, controls pituitary tumors.</p>Formule :C26H37N5O2Degré de pureté :97.69% - 99.86%Couleur et forme :White Crystalline SolidMasse moléculaire :451.6AChE/BChE-IN-22
<p>AChE/BChE-IN-22 (compound 7) exhibits competitive inhibition against both AChE and BChE enzymes, with inhibition constants of 28.18 μM and 41.74 μM respectively.</p>Formule :C14H11F3N2O4SCouleur et forme :SolidMasse moléculaire :360.31BChE-IN-10
CAS :<p>BChE-IN-10, a strong mixed BChE inhibitor (IC50=6.4 μM), comes from Bletilla striata for AD research.</p>Formule :C23H20O5Couleur et forme :SolidMasse moléculaire :376.4Riluzole-13C,15N2
CAS :<p>Riluzole-13C,15N2 (PK 26124-13C,15N2) is a 13C and 15N labeled form of Riluzole, a glutamate antagonist with anticonvulsant activity, inhibiting GABA uptake.</p>Formule :CC7H5F3OS15N2Couleur et forme :SolidMasse moléculaire :237.18Aminoacetone hydrochloride
CAS :<p>Aminoacetone hydrochloride (1-Aminoacetone Hydrochloride) is an oxidative agent that induces loss of ferritin ferrireductase activity and iron uptake.</p>Formule :C3H8ClNODegré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :109.56MGS0274
CAS :<p>MGS0274, a lipophilic prodrug of mGlu2/3 agonist MGS0008, enhances oral bioavailability, potentially aiding schizophrenia research.</p>Formule :C21H32FNO7Couleur et forme :SolidMasse moléculaire :429.485[D-Trp7,9,10]-Substance P
CAS :<p>Substance P analog that inhibits activation of Gq/11 by M1 muscarinic ACh receptors. Does not inhibit Gi/o activation by M2 ACh receptors.</p>Formule :C79H105N21O13SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1588.89AChE-IN-34
<p>AChE-IN-34 (compound 5l) is a potent, selective AChE inhibitor exhibiting an IC50 of 3.98 µM and negligible BChE inhibition.</p>Formule :C19H14N8O6Couleur et forme :SolidMasse moléculaire :450.36AChE-IN-39
<p>AChE-IN-39 (Compound 7c), with an IC50 value of 0.058 μM, is an acetylcholinesterase (AChE) inhibitor known for its DPPH scavenging activity and potential to</p>Formule :C19H15NO3Couleur et forme :SolidMasse moléculaire :305.33VU6028418
CAS :<p>VU6028418 is a highly selective, potent, orally active M4mAChR antagonist that acts on hM4 (IC50: 4.1 nM).</p>Couleur et forme :SolidTMPH
CAS :<p>TMPH is an inhibitor of nAChR and inhibits nAChRs lacking α5, α6, or β3 subunits. TMPH can be used in studies about nAChR dysfunction or neurological disorders.</p>Formule :C16H31NO2Degré de pureté :99.78%Couleur et forme :SoildMasse moléculaire :269.42β-Amyloid (1-15)
CAS :<p>β-Amyloid (1-15) (Amyloid β-Protein (1-15)) is a fragment of β-amyloid protein used in the study of Alzheimer's disease.</p>Formule :C78H107N25O27Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :1826.84Minaprine
CAS :<p>Minaprine is a reversible inhibitor of MAO-A, used in the treatment of various depressive states.</p>Formule :C17H22N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :298.38Inaperisone
CAS :<p>Inaperisone: a novel muscle relaxant that indirectly inhibits voiding reflex via brainstem GABAB receptors.</p>Formule :C16H23NODegré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :245.36(Gln22)-Amyloid β-Protein (1-42)
CAS :<p>(Gln22)-Amyloid β-Protein (1-42), a Dutch mutation (E22Q) variant of β-Amyloid (1-42), demonstrates increased fibrillogenic and pathogenic characteristics [1].</p>Formule :C203H312N56O59SCouleur et forme :SolidMasse moléculaire :4513.05Orexin B, rat, mouse TFA
<p>Orexin B, rat/mouse TFA, activates OX1-R & OX2-R receptors, influencing food intake, energy, and sleep regulation.</p>Formule :C128H216F3N45O36SCouleur et forme :SolidMasse moléculaire :3050.42Acetyl-Tau Peptide (273-284) amide
CAS :<p>Acetyl-Tau Peptide (273-284) amide inhibits Ac-Aβ(25–35)-NH2 aggregation and models Aβ/Tau interaction.</p>Formule :C64H116N18O17Couleur et forme :SolidMasse moléculaire :1409.72ZZL-7
CAS :<p>ZZL-7 is a rapid antidepressant targeting nNOS & SERT in DRN, crosses blood-brain barrier, with MDD research potential.</p>Formule :C11H20N2O4Degré de pureté :99.79%Couleur et forme :SoildMasse moléculaire :244.29Anti-Amyloid β Antibody (scFv59)
<p>Anti-Amyloid Beta Antibody (scFv59) is a human-derived antibody produced in CHO cells that targets Amyloid-β. For isotype control, please refer to Human IgG1 kappa, Isotype Control.</p>Couleur et forme :Odour LiquidOM99-2 TFA
CAS :<p>OM99-2 TFA, an 8-residue inhibitor of brain memapsin 2, has a Ki of 9.58 nM, showing promise in Alzheimer's research.</p>Formule :C43H65F3N8O16Couleur et forme :SolidMasse moléculaire :1007.028Endosulfan I
CAS :<p>Endosulfan I is one of the two major stereoisomers of the broad-spectrum insecticide Endosulfan inhibi the GABA/benzodiazepine/picrotoxin complex</p>Formule :C9H6Cl6O3SDegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :406.93mcK6A1
<p>mcK6A1 serves as an inhibitor of amyloid-β (Aβ) aggregation, selectively binding to the 16KLVFFA21 fragment of Aβ42, leading to the formation of an extended β-sheet structure and preventing the formation of Aβ42 oligomers. This compound is valuable for research into Alzheimer's disease and other amyloid-related disorders.</p>Formule :C71H99N17O16Couleur et forme :SolidMasse moléculaire :1446.65β-Amyloid (1-38), mouse, rat
CAS :<p>β-Amyloid (1-38), derived from mice and rats, is a chemical compound comprising 38 amino acids, specifically residues 1-38 of the Aβ peptide.</p>Couleur et forme :SolidOrexin B, rat, mouse
CAS :<p>Orexin B, rat, mouse is an endogenous agonist at Orexin receptor with Kis of 420 and 36 nM for OX1 and OX2, respectively.</p>Formule :C126H215N45O34SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :2936.45(D-Asp1)-Amyloid β-Protein (1-42)
CAS :<p>(D-Asp1)-Amyloid β-Protein (1-42), a peptide fragment of amyloid β-protein (Aβ), serves as the primary constituent of vascular and parenchymal amyloid deposits</p>Formule :C203H311N55O60SCouleur et forme :SolidMasse moléculaire :4514.04Laniquidar TFA
<p>Laniquidar TFA (R101933), a non-competitive P-gp inhibitor, has an IC50 of 0.51 μM; used to study AML and MDS, but with limited bioavailability.</p>Formule :C39H37F3N4O5Degré de pureté :99.85%Couleur et forme :SoildMasse moléculaire :698.73Suntinorexton
CAS :<p>Suntinorexton (TAK 861) is an orexin type 2 receptor (OX2R) agonist used in the study of neurologic disorders.</p>Formule :C23H28F2N2O4SDegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :466.542002-H20
CAS :<p>2002-H20 is an Aβ42-induced cytotoxicity inhibitor. It acts by binding the Alzheimer's Aβ peptide and reducing its cytotoxicity.</p>Formule :C20H15N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :345.358Furosemide
CAS :<p>Furosemide is a potent NKCC2 (Na-K-2Cl symporter) inhibitor, used for edema and chronic renal insufficiency.</p>Formule :C12H11ClN2O5SDegré de pureté :99.32% - 99.89%Couleur et forme :Crystals From Aqueous Ethanol Tasteless (Ntp 1992)Masse moléculaire :330.744BChE-IN-35
<p>BChE-IN-35 (Azo-9) is an inhibitor of BChE. This compound exhibits dynamic cis/trans conformational changes, with the cis isomer preferentially binding to BChE. Additionally, BChE-IN-35 can be utilized in research on Alzheimer's disease (AD).</p>Formule :C35H39N5O2Couleur et forme :SolidMasse moléculaire :561.72Fluphenazine-N-2-chloroethane (hydrochloride)
CAS :<p>Fluphenazine: antipsychotic, binds dopamine D2 (Ki=0.55nM), inhibits calmodulin. Its derivative adds irreversible D2 antagonism and anticancer potential.</p>Formule :C22H27Cl3F3N3SCouleur et forme :SolidMasse moléculaire :528.89Dual AChE-MAO B-IN-3
<p>Compound C10 is a potent dual AChE/MAO-B inhibitor with IC50s of 0.58μM (AChE) and 0.41μM (MAO-B), useful in Alzheimer's research.</p>Formule :C30H26F3NO3Couleur et forme :SolidMasse moléculaire :505.53Ebiratide TFA
<p>Ebiratide (HOE-427) TFA is a derivative of ACTH4-9 that exerts its effect directly on the central nervous system, enhancing memory. Ebiratide TFA also promotes the metabolism of acetylcholine (ACh) in the rat brain.</p>Formule :C48H73N11O10S·xC2HF3O2Couleur et forme :SolidMasse moléculaire :996.23 (free base)Lisuride maleate
CAS :<p>Lisuride maleate is a non-selective dopamine agonist and G-protein-biased 5-HT2A receptor agonist capable of blocking prolactin release.</p>Formule :C24H30N4O5Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :454.52Tranylcypromine
CAS :<p>Tranylcypromine (SKF 385), a potent monoamine oxidase (MAO) inhibitor [1], is used in medicinal applications.</p>Formule :C9H11NDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :133.19COX-2-IN-35
<p>COX-2-IN-35 (compound 7) is a selective inhibitor of COX-2, demonstrating anti-inflammatory activity, with an inhibitory concentration (IC 50) of 4.37 nM [1].</p>Formule :C22H19NO2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :393.52Hydroxytacrine maleate
CAS :<p>Hydroxytacrine maleate (Velnacrine maleate) is a cholinesterase inhibitor used in the study of Alzheimer's type dementia (SDAT).</p>Formule :C17H18N2O5Degré de pureté :98.84%Couleur et forme :SolidMasse moléculaire :330.34Arotinolol hydrochloride
CAS :<p>Arotinolol HCl is a non-selective α/β-blocker, anti-hypertensive, anti-obesity, and improves aortic stiffness.</p>Formule :C15H22ClN3O2S3Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :408SIB 1553A
CAS :<p>SIB 1553A is an agonist of nAChRs, a cognitive enhancer that can be used to study diseases associated with neurodegeneration.</p>Formule :C13H19NOSDegré de pureté :99.79%Couleur et forme :SoildMasse moléculaire :237.36MAO-B-IN-4
<p>MAO-B-IN-4 (Compound 26) is a reversible monoamine oxidase B (MAO-B) inhibitor with potent in vitro activity, characterized by an IC50 value of 9 nM.</p>Formule :C23H20ClF2N3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :411.87Trontinemab
CAS :<p>Trontinemab, a bispecific humanized IgG1-κ antibody, targets the amyloid beta A4 precursor protein (APP) and transferrin receptor p90, CD71 (TFRC).</p>Degré de pureté :96.77% - 99%Couleur et forme :LiquidLysyl hydroxylase 2-IN-1
<p>"Lysyl Hydroxylase 2-IN-1 (compound 12) is a selective inhibitor of lysyl hydroxylase 2 (LH2) with an IC50 of approximately 300 nM and demonstrates specificity</p>Formule :C18H18N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :310.35Methyllycaconitine citrate
CAS :<p>Methyllycaconitine citrate (MLA) is an α7 neuronal nicotinic acetylcholine receptor (α7nAChR) antagonist that crosses the blood-brain barrier.</p>Formule :C43H58N2O17Degré de pureté :98.03% - 98.91%Couleur et forme :SolidMasse moléculaire :874.92C18 L-erythro Ceramide (d18:1/18:0)
CAS :<p>C18 L-erythro Ceramide, a natural stereoisomer, inhibits rat brain mt-CDase with IC50 of 8.8 μM.</p>Formule :C36H71NO3Couleur et forme :SolidMasse moléculaire :565.95LRRK2 inhibitor 1
CAS :<p>LRRK2 inhibitor 1 is a selective and potent LRRK2 inhibitor with an IC50 of 13 nM.LRRK2 inhibitor 1 inhibits DCLK1 kinase with an IC50 value of 2.61 nM.</p>Formule :C20H23N5O4Degré de pureté :99.94%Couleur et forme :SolidMasse moléculaire :397.43NMDA receptor antagonist 7
<p>Compound (S)-10a, a GluN2B subunit-selective NMDA receptor antagonist, exhibits a K i of 93 nM and an IC 50 of 72 nM.</p>Formule :C22H27N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :349.47Lu AF27139
CAS :<p>Lu AF27139: P2X7 receptor antagonist; IC50: 12 nM (human), 2.4 nM (rat); Ki: 22 (mouse), 54 (human), 13 nM (rat); for CNS research.</p>Formule :C21H19ClF3N5O2SDegré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :497.924-hydroxy DiPT hydrochloride
CAS :<p>4-hydroxy DiPT (hydrochloride) is a 5-HT2A agonist that can induce head twitch response (HTR) in mice, indicating its hallucinogenic potential. This compound holds promise for research into hallucinogens.</p>Formule :C16H25ClN2OCouleur et forme :SolidMasse moléculaire :296.84Methamnetamine hydrochloride
CAS :<p>Methamnetamine (PAL-1046) hydrochloride is a psychoactive substance derived from phenethylamine, known to cause excessive serotonin release.</p>Formule :C14H18ClNCouleur et forme :SolidMasse moléculaire :235.75MAO-B-IN-37
CAS :<p>MAO-B-IN-37 (Compound 37) is a derivative of TT01001 and acts as a selective inhibitor of monoamine oxidase B (MAO-B), with an IC50 of 270 nM. It exhibits good metabolic stability in mouse microsomes and shows strong affinity for human serum albumin.</p>Formule :C14H12FN3O3Couleur et forme :SolidMasse moléculaire :289.26EB-42486
CAS :<p>EB-42486 is an effective and highly selective inhibitor of G2019S-LRRK2 with an IC50 < 0.2 nM.</p>Formule :C22H22N8ODegré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :414.466-Fluoro-N,N-diethyltryptamine
CAS :<p>6-Fluoro-N,N-diethyltryptamine (6-F-DET) exhibits affinity for the 5-HT2A receptor.</p>Formule :C14H19FN2Couleur et forme :SolidMasse moléculaire :234.31Methyl piperate
CAS :<p>Methylpiperic acid, a piperine alkaloid, exhibits potent inhibitory activity on monoamine oxidase (MAO), with differing efficacy on isoforms: greater inhibition</p>Formule :C13H12O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :232.23COX-1/2-IN-4
<p>COX-1/2-IN-4 (compound 2b) is a dual COX-1 and COX-2 inhibitor with respective IC50 values of 0.239 μM for COX-1 and 0.191 μM for COX-2.</p>Formule :C22H24N2O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :380.525E-NBOMe hydrochloride
CAS :<p>25E-NBOMe hydrochloride is a derivative of 2C-E, featuring an N-(2-methoxybenzyl) addition to the amine group, and acts as a selective agonist of the 5-HT2A receptor.</p>Formule :C20H28ClNO3Couleur et forme :SolidMasse moléculaire :365.89Argiotoxin 636
CAS :<p>Argiotoxin 636 is a toxin and serves as a non-specific, non-competitive, and effective antagonist of ionotropic glutamate receptors (iGluR). It inhibits excitatory synaptic transmission in neurons and has paralyzing and muscle relaxant effects. Argiotoxin 636 can be utilized for research in neurological disorders.</p>Formule :C29H52N10O6Couleur et forme :SolidMasse moléculaire :636.79MAO-B-IN-24
<p>MAO-B-IN-24 (compound 11h) is a selective, reversible, competitive inhibitor of MAO-B with an IC50 value of 1.60 μM.</p>Formule :C20H18N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :302.37(-)-2-Phenylpropylamine
CAS :<p>(-)-2-Phenylpropylamine ((S)-2-Phenylpropylamine) (compound 3b) functions as an inhibitor for both MAO-A and MAO-B, with Ki values of 584 μM and 156 μM, respectively.</p>Formule :C9H13NCouleur et forme :SolidMasse moléculaire :135.21TB-11
CAS :<p>TB-11 is an inhibitor of Cathepsin D with IC50 values of 0.126 nM (Cathepsin D), 1.92 nM (Cathepsin E), and 48.8 nM (BACE1). It is primarily utilized in oncological research.</p>Formule :C52H78N8O12Couleur et forme :SolidMasse moléculaire :1007.22hAChE-IN-3
<p>hAChE-IN-3 (compound 5c) serves as a potent inhibitor for AChE, BuChE, MAO-B, and BACE-1, with respective IC50 values of 0.44, 0.08, 5.15, and 0.38 μM,</p>Formule :C30H24ClN3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :541.98Litoxetine HCl
<p>Litoxetine HCl, an SSRI and 5-HT antagonist, treats urinary incontinence and relaxes rat oesophageal muscles without antimuscarinic effects.</p>Formule :C16H20ClNODegré de pureté :99.56% - 99.75%Couleur et forme :SoildMasse moléculaire :277.79Pyrazolam
CAS :<p>Pyrazolam is a psychoactive benzodiazepine compound serving as a central nervous system depressant. [Pyrazolam] can lead to psychomotor impairment.</p>Formule :C16H12BrN5Couleur et forme :SolidMasse moléculaire :354.22,6-DMA hydrochloride
CAS :<p>2,6-DMA hydrochloride is a phenethylamine and acts as an agonist of the serotonin 5-HT2 receptor, with a pA2 value of 5.09.</p>Formule :C11H18ClNO2Couleur et forme :SolidMasse moléculaire :231.72NMDA receptor antagonist 8
<p>Compound (R)-10a, an NMDA receptor antagonist, exhibits selectivity for the GluN2B subunit, possessing a Ki of 265 nM and an IC50 of 62 nM.</p>Formule :C22H27N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :349.47AChE/BChE-IN-25
<p>AChE/BChE-IN-25 (Compound 6e) is an orally active inhibitor of hAChE and eqBChE, with IC50 values of 7.9 nM and 0.79 nM, respectively. This compound exhibits antioxidant activity, effective in scavenging free radicals with an IC50 of 22.91 μM. AChE/BChE-IN-25 demonstrates neuroprotective effects by reducing mitochondrial and cellular oxidative stress in a Drosophila Alzheimer's model and improves spatial and cognitive memory impairments induced by Scopolamine in mouse models.</p>Formule :C21H24ClN3O2Couleur et forme :SolidMasse moléculaire :385.89Anti-inflammatory agent 53
<p>Anti-inflammatory agent 52 (compound 7c) is an orally active, selective COX-2 inhibitor with demonstrated anti-HT29 metastatic activity, causing periodic arrest</p>Formule :C24H22N2O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :434.51JPC0323
<p>JPC0323 is a dual positive allosteric modulator of the 5-HT2C and 5-HT2A receptors, featuring on-target properties, acceptable plasma exposure, and adequate</p>Formule :C22H43NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :385.58Orexin A (human, rat, mouse)
CAS :<p>Orexin A, a 33 AA neuropeptide in humans, rats, mice, influences various processes, studied in pancreatic function and as an OX1R antagonist.</p>Formule :C152H243N47O44S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3561.1Vortioxetine D8
CAS :<p>Vortioxetine D8 is a deuterium-labeled antidepressant inhibiting 5-HT1A/B, 5-HT3A, 5-HT7 receptors & SERT (Ki: 15-1.6 nM).</p>Formule :C18H22N2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :306.5Br-PBTC
CAS :<p>Br-PBTC modulates nAChRs; targets α2/β2,4 subtypes; potent with 0.1-0.6 μM EC50; binds α subunit c-tail.</p>Formule :C14H15BrN2OSCouleur et forme :SolidMasse moléculaire :339.25TC-2559 difumarate
CAS :<p>TC-2559 difumarate: Oral α4β2 nAChR partial agonist, CNS-selective, EC50 0.18 μM, prefers α4β2 over α2β4/α4β4/α3β4, antinociceptive.</p>Formule :C20H26N2O9Couleur et forme :SolidMasse moléculaire :438.43Brexpiprazole S-oxide D8
CAS :<p>Brexpiprazole S-oxide D8 (DM-3411 D8) is a deuterium-labeled metabolite of Brexpiprazole, a partial agonist at 5-HT1A and dopamine receptors.</p>Formule :C25H19D8N3O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :457.61Nardoguaianone J
CAS :<p>Nardoguaianone J, a guaiane-type compound isolated from the roots of Nardostachys chinensis, has been shown to enhance SERT activity [1][2].</p>Formule :C15H22O2Couleur et forme :SolidMasse moléculaire :234.33SB656104
CAS :<p>SB656104 is a bioactive chemical.</p>Formule :C25H30ClN3O3SCouleur et forme :SolidMasse moléculaire :488.04Methoxy-X04
CAS :<p>Methoxy-X04, a derivative of Congo red and Chrysamine-G, is a brain-permeable fluorescent probe for amyloid-β (Aβ).</p>Formule :C23H20O3Degré de pureté :98.96%Couleur et forme :SolidMasse moléculaire :344.4epi-Aszonalenin A
CAS :<p>epi-Aszonalenin A: a psychoactive benzodiazepine from Aspergillus novofumigatus.</p>Formule :C25H25N3O3Couleur et forme :SolidMasse moléculaire :415.48COX-1/2-IN-9
<p>COX-1/2-IN-9 (Compound 3n) serves as a selective and potent inhibitor of both COX-1 and COX-2, demonstrating IC 50 values of 0.031 µM for COX-1 and 0.01 µM for COX-2. This compound exhibits antibacterial and anti-inflammatory properties, effectively targeting MRSA 1478 (MIC=50 μg/mL) and multidrug-resistant S. lentus (MIC=50 μg/mL). Furthermore, COX-1/2-IN-9 shows promise in relieving MRSA-induced pneumonia in conditions of compromised immunity.</p>Formule :C30H20IN9O13S2Couleur et forme :SolidMasse moléculaire :905.57Triazolomethylindole-3-acetic acid
CAS :<p>Triazolomethylindole-3-acetic acid is a metabolite of Rizatriptan, which acts as an agonist for the serotonin (5-HT) receptor subtypes 5-HT1B and 5-HT1D.</p>Formule :C13H12N4O2Couleur et forme :SolidMasse moléculaire :256.26COX-2-IN-46
<p>COX-2-IN-46 (compound 5m) serves as a potent anti-inflammatory and analgesic agent. It demonstrates a significant inhibitory action on COX-2, with an IC 50 value of 87.74 nM.</p>Formule :C28H19F2N3SCouleur et forme :SolidMasse moléculaire :467.53Zicronapine fumarate
CAS :<p>Zicronapine fumarate, an antipsychotic, targets D1/D2 & 5-HT2A receptors; may treat neuropsychiatric conditions.</p>Formule :C26H31ClN2O4Couleur et forme :SolidMasse moléculaire :470.99TRV-7019
CAS :<p>TRV-7019: BBB-permeable radioligand for brain imaging, used in diagnosing amyloid diseases, MS, and brain tumors.</p>Formule :C14H12INO3Couleur et forme :SolidMasse moléculaire :369.15Cevimeline hydrochloride hemihydrate
CAS :<p>Cevimeline hydrochloride hemihydrate is a novel muscarinic receptor agonist, used as a candidate therapeutic drug for xerostomia in Sjogren's syndrome.</p>Formule :C20H38Cl2N2O3S2Degré de pureté :97.00%Couleur et forme :SolidMasse moléculaire :489.55TAT-CN21
<p>TatCN21, with an IC 50 of 77 nM, serves as a potent and selective inhibitor peptide of the calcium/calmodulin-dependent protein kinase II (CaMKII), a ubiquitously-expressed multifunctional serine/threonine protein kinase. It is particularly useful in research pertaining to ischemia and neurodegenerative diseases.</p>Formule :C169H303N69O43Couleur et forme :SolidMasse moléculaire :3989.65Jatrorrhizine hydroxide
CAS :<p>Jatrorrhizine hydroxide: alkaloid from Coptis chinensis; neuroprotective, antimicrobial, antiplasmodial, antioxidant; AChE inhibitor, affects 5-HT/NE uptake.</p>Formule :C20H21NO5Couleur et forme :SolidMasse moléculaire :355.38Asenapine citrate
CAS :<p>Asenapine citrate: atypical antipsychotic for schizophrenia, bipolar disorder; targets serotonin, adrenoceptors, dopamine, histamine (pKi: 8.2-10.5).</p>Formule :C23H24ClNO8Couleur et forme :SolidMasse moléculaire :477.89α-Conotoxin EI
CAS :<p>Selective antagonist of neuromuscular nicotinic receptors α1β1γδ</p>Formule :C83H125N27O27S5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2093.37COX-1-IN-2
<p>COX-1-IN-2 (compound 5h) serves as a potent anti-inflammatory and analgesic agent. This compound demonstrates a significant inhibitory effect on COX-1, with an IC 50 value of 38.76 nM.</p>Formule :C29H22FN3OSCouleur et forme :SolidMasse moléculaire :479.57β-Amyloid (35-42)
CAS :<p>β-Amyloid (35-42) is a peptide derived from the beta-amyloid protein, encompassing amino acids 35 through 42.</p>Formule :C33H60N8O9SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :744.94Blestrin D
CAS :<p>Blestrin D: BChE mixed-type inhibitor, IC50=8.1μM, from Bletilla striata, for AD research.</p>Formule :C30H24O6Couleur et forme :SolidMasse moléculaire :480.51GABAA receptor modulator-3
<p>GABAA receptor modulator-3 (compound 3b) is a positive allosteric modulator (PAM). It inhibits the peak current and steady-state current of α1β3γ2 GABAAR with IC50 values of 671 μM and 64 μM, respectively.</p>Formule :C18H22O2Couleur et forme :SolidMasse moléculaire :270.37AChE-IN-37
<p>AChE-IN-37 (compound A2) is an acetylcholinesterase inhibitor with an inhibitory concentration (IC50) of 0.23 µM.</p>Formule :C21H12ClNO7SCouleur et forme :SolidMasse moléculaire :457.84GABAA receptor modulator-4
<p>GABAA receptor modulator-4 (Compound 4) acts as a negative allosteric modulator of the GABAA receptor. It inhibits the peak and steady-state currents mediated by the α1β3γ2 GABAA receptors, with an IC50 of 10 μM for both.</p>Formule :C15H17BrO4SCouleur et forme :SolidMasse moléculaire :373.26α-Casozepine
CAS :<p>α-Casozepine,Bioactive peptide from milk α-S1 casein. Binds GABA receptors. Anti-anxiety effects.</p>Formule :C60H94N14O16Couleur et forme :SolidMasse moléculaire :1267.47hAChE/hBuChE-IN-1
<p>hAChE/hBuChE-IN-1 (compound C2) acts as a dual inhibitor of cholinesterases, exhibiting IC50 values of 514 nM for hAChE and 358 nM for hBuChE. It is orally active and capable of enhancing cognitive function and spatial memory.</p>Formule :C30H31FN2O3Couleur et forme :SolidMasse moléculaire :486.577(R)-(+)-Anatabine
CAS :<p>(R)-(+)-Anatabine is an less active R-enantiomer of Anatabine. Anatabine is a potent agonist of α4β2 nAChR.</p>Formule :C10H12N2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :160.22AC1-IN-1
CAS :<p>AC1-IN-1 is a selective inhibitor of adenylyl cyclase type 1 (AC1, IC50 = 0.54 µM).</p>Formule :C18H18FN5O2Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :355.37[Ala11,D-Leu15]-Orexin B(human)
CAS :<p>OX2 receptor agonist with 400x selectivity vs OX1. EC50: 0.13 nM (OX2), 52 nM (OX1).</p>Formule :C120H206N44O35SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :2857.28AChE/BuChE-IN-6
<p>AChE/BuChE-IN-6 (Compound 11f) is an inhibitor of AChE and BuChE, with IC50 values of 1.24 and 1.85 μg/mL, respectively. It exhibits strong DPPH radical scavenging activity (IC50 = 3.15 μg/mL). In vivo toxicity studies demonstrate that AChE/BuChE-IN-6 is safe, showing no significant differences in blood and biochemical parameters compared to controls, and no abnormalities in liver and kidney tissues. This compound shows potential for Alzheimer's disease research.</p>Formule :C24H20ClN3O3Couleur et forme :SolidMasse moléculaire :433.887Monoamine oxidase
CAS :<p>Enzyme that breaks down amines in the brain and body, affecting mood and brain function.</p>Couleur et forme :SolidBencycloquidium Bromide
CAS :<p>Bencycloquidium bromide is an M3 muscarinic antagonist that reduces nasal secretion in allergic rhinitis and has high affinity for M3 receptors.</p>Formule :C21H32BrNO2Couleur et forme :SolidMasse moléculaire :410.39Orexin B, human
CAS :<p>Orexin B, human agonizes Orexin receptors (OX1 Ki=420 nM, OX2 Ki=36 nM), promotes feeding in rats, and is a neuropeptide.</p>Formule :C123H212N44O35SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :2899.34
![[Ala11,D-Leu15]-Orexin B acetate](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTP1975L.webp&w=3840&q=75)
![[D-Trp7,9,10]-Substance P](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTP1932.webp&w=3840&q=75)
![[Ala11,D-Leu15]-Orexin B(human)](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTP1975.webp&w=3840&q=75)
