Neuroscience

Les inhibiteurs en neurosciences sont des composés conçus pour moduler l'activité de protéines, d'enzymes ou de récepteurs spécifiques au sein du système nerveux. Ces inhibiteurs sont cruciaux pour étudier les mécanismes moléculaires sous-jacents au fonctionnement neuronal, à la transmission synaptique et aux maladies neurodégénératives. En ciblant les récepteurs des neurotransmetteurs, les canaux ioniques et les voies de signalisation, les inhibiteurs en neurosciences facilitent l'exploration du fonctionnement cérébral et le développement de stratégies thérapeutiques pour des troubles neurologiques tels que la maladie d'Alzheimer, de Parkinson et l'épilepsie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs en neurosciences de haute qualité pour soutenir vos recherches en neurobiologie, neuropharmacologie et sciences cognitives.

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Emraclidine
CAS :
- 2170722-84-4
Emraclidine (CVL-231) is a novel, highly selective allosteric modulator of the muscarinic M4 receptor positive receptor.Cost-effective and quality-assured.
Formule :C₂₀H₂₁F₃N₄O
Degré de pureté :99.96%
Couleur et forme :Solid
Masse moléculaire :390.4
Ref: TM-T9694
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Sintamil
CAS :
- 16398-39-3
Sintamil is a useful organic compound for research related to life sciences. The catalog number is T71697 and the CAS number is 16398-39-3.
Formule :C₁₈H₂₀ClN₃O₄
Couleur et forme :Solid
Masse moléculaire :377.82
Ref: TM-T71697
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Quetiapine-d4 fumarate
CAS :
- 1287376-15-1
Deuterium-labeled Quetiapine fumarate; an antidepressant and anxiolytic 5-HT agonist, dopamine antagonist.
Formule :C₂₅H₂₉N₃O₆S
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :503.61
Ref: TM-T12618
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Aβ-IN-8
Aβ-IN-8, also known as compound 7e, is a potent inhibitor of Aβ aggregation [1].
Formule :C₂₂H₁₆F₃N₃O₃S
Couleur et forme :Solid
Masse moléculaire :459.44
Ref: TM-T78885
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5β-Cholanic acid
CAS :
- 546-18-9
5β-Cholanic acid (5beta-Cholanic acid) is a potent γ-secretase modulator used in Alzheimer's disease research.
Formule :C₂₄H₄₀O₂
Degré de pureté :98.91% - 99.89%
Couleur et forme :Soild
Masse moléculaire :360.57
Ref: TM-T88859
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NF023 hexasodium
CAS :
- 104869-31-0
NF023 hexasodium is a selective and competitive P2X1 receptor antagonist, with IC50 values of 0.21 μM, 28.9 μM, > 50 μM and > 100 μM for human P2X1, P2X3, P2X2
Formule :C₃₅H₂₆N₄Na₆O₂₁S₆
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :1168.92
Ref: TM-TP2272
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α-Conotoxin PIA TFA
α-Conotoxin PIA TFA, targeting nicotinic acetylcholine receptor (nAChR) subtypes with α6 and α3 subunits, acts as an antagonist.
Formule :C₈₁H₁₂₆F₃N₂₇O₂₇S₄
Degré de pureté :98.81%
Couleur et forme :Solid
Masse moléculaire :2095.3
Ref: TM-T75876
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AChE/BuChE/MAO-B-IN-2
AChE/BuChE/MAO-B-IN-2 (compound 4b) is a potent inhibitor of AChE, BuChE, and hu MAO-B, with respective IC50 values of 5.3 μM, 12.4 μM, and 1.9±0.08 μM,
Formule :C₁₉H₁₈FNO₃
Couleur et forme :Solid
Masse moléculaire :327.35
Ref: TM-T78679
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γ-Secretase Modulators
CAS :
- 937812-80-1
gamma-Secretase Modulators serves as a useful treatment for Alzheimer's disease by inhibiting the production of Amyloid-β.
Formule :C₂₆H₂₄F₃N₃O₃
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :483.48
Ref: TM-T11362
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4-fluoro MBZP
CAS :
- 144734-44-1
4-fluoro MBZP is a novel psychoactive substance in the phenylpiperazine class, utilized for studies on the 5-HT2 receptors in the central nervous system.
Formule :C₁₂H₁₇FN₂
Couleur et forme :Solid
Masse moléculaire :208.28
Ref: TM-T203276
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Guanylyl Imidodiphosphate (lithium salt)
CAS :
- 64564-03-0
Guanylyl Imidodiphosphate (lithium salt) is a non-hydrolyzable GTP analog that increases adenylate cyclase activity.
Formule :C₁₀H₁₃Li₄N₆O₁₃P₃
Couleur et forme :Solid
Masse moléculaire :545.93
Ref: TM-T36009
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Methylatropine (nitrate)
CAS :
- 52-88-0
Methylatropine: Muscarinic antagonist, <0.1 nM IC50, atropine derivative, lowers ACh's effect on BP, affects salivation, pupil dilation, heart rate.
Formule :C₁₈H₂₆N₂O₆
Couleur et forme :Solid
Masse moléculaire :366.414
Ref: TM-T36204
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mGluR5 modulator 1
CAS :
- 1261171-52-1
mGluR5 modulator 1 is a positive modulator for mGluR5, used in schizophrenia and cognitive research.
Formule :C₁₈H₁₉ClFN₃O₂
Couleur et forme :Solid
Masse moléculaire :363.82
Ref: TM-T38659
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N-Desmethyl Pimavanserin
CAS :
- 639863-77-7
N-Desmethyl Pimavanserin (AC-279) is the active metabolite of Pimavanserin and is used in the treatment of insomnia and other sleep disorders.
Formule :C₂₄H₃₂FN₃O₂
Degré de pureté :98.02%
Couleur et forme :Solid
Masse moléculaire :413.53
Ref: TM-T37979
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sabcomeline
CAS :
- 159912-53-5
Sabcomeline: potent, selective M1 agonist; boosts cognition; for Alzheimer's study.
Formule :C₁₀H₁₅N₃O
Couleur et forme :Solid
Masse moléculaire :193.25
Ref: TM-T68135
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β-Amyloid (1-28)
CAS :
- 109770-29-8
β-Amyloid (1-28) is a β-Amyloid protein fragment involved in metal binding.
Formule :C₁₄₅H₂₀₉N₄₁O₄₆
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :3262.51
Ref: TM-TP1226
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Rivanicline 2HCl
Rivanicline 2HCl is a selective neuronal nicotinic receptor inhibitor with a high affinity for the α4β2 subtype.
Formule :C₁₀H₁₆Cl₂N₂
Degré de pureté :99.4%
Couleur et forme :Soild
Masse moléculaire :235.15
Ref: TM-T12738L1
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Ro60-0175
CAS :
- 169675-08-5
Ro60-0175 is a selective 5-HT2B and 5-HT2C serotonin receptor agonist, often used as fumarate.
Formule :C₁₁H₁₂ClFN₂
Degré de pureté :97.09%
Couleur et forme :Solid
Masse moléculaire :226.68
Ref: TM-T39161
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4-Chloromethamphetamine hydrochloride
CAS :
- 30572-91-9
4-Chloromethamphetamine hydrochloride is a novel psychoactive substance belonging to the amphetamine class.
Formule :C₁₀H₁₅Cl₂N
Couleur et forme :Solid
Masse moléculaire :220.14
Ref: TM-T203542
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Galanin (1-15) (porcine, rat)
CAS :
- 112747-70-3
N-terminal galanin fragment used to mediate central cardiovascular effects
Formule :C₇₂H₁₀₅N₁₉O₂₀
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :1556.72
Ref: TM-TP2250
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SB-408124
CAS :
- 288150-92-5
SB408124: Non-peptide, OX1 receptor antagonist, Ki 57 nM (whole cell) and 27 nM (membrane), 50x more selective than OX2.
Formule :C₁₉H₁₈F₂N₄O
Degré de pureté :99.81%
Couleur et forme :Solid
Masse moléculaire :356.37
Ref: TM-T6658
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(-)-Eseroline fumarate
CAS :
- 70310-73-5
(-)-Eseroline fumarate, a Physostigmine metabolite and AChE inhibitor, triggers cancer cell LDH release and neuronal cell death.
Formule :C₁₇H₂₂N₂O₅
Couleur et forme :Solid
Masse moléculaire :334.37
Ref: TM-T73930
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β-Amyloid (11-22)
CAS :
- 885323-98-8
β-Amyloid (11-22) is a peptide fragment of β-Amyloid.Beta-amyloid peptide (Abeta), the major constituent of amyloid plaques in the brains of Alzheimer’s
Formule :C₇₀H₁₀₂N₁₈O₁₈
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :1483.67
Ref: TM-TP1673
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mHTT-IN-1
CAS :
- 2839311-21-4
mHTT-IN-1 is a potent inhibitor of toxic mHTT, linked to Huntington's disease, with an EC50 of 46 nM.
Formule :C₁₈H₁₉N₇OS
Couleur et forme :Solid
Masse moléculaire :381.45
Ref: TM-T73289
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Zanapezil free base
CAS :
- 142852-50-4
Zanapezil (TAK-147): potent, selective AChE inhibitor; reversible; IC50=51.2 nM; moderate M1/M2 inhibition; AD research potential.
Formule :C₂₅H₃₂N₂O
Couleur et forme :Solid
Masse moléculaire :376.544
Ref: TM-T38895
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SKF-83566 hydrochloride
CAS :
- 164265-49-0
SKF-83566 hydrochloride is a D1-like dopamine receptor antagonist, inhibiting dopamine transporters and mitigating GBP-induced CPP.
Formule :C₁₇H₁₉BrClNO
Degré de pureté :99.27%
Couleur et forme :Soild
Masse moléculaire :368.69
Ref: TM-T8702L
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Nipecotic acid
CAS :
- 498-95-3
Compound PDK0243, with CAS No. 498-95-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0243 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.
Formule :C₆H₁₁NO₂
Couleur et forme :Off-White To Pale Yellow-Beige Powder
Masse moléculaire :129.16
Ref: TM-PDK0243
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PSEN1-IN-1
PSEN1-IN-1 (Compound (+)-13b) functions as an inhibitor of PSEN1, displaying potent inhibition of the PSEN1-APH1A and PSEN1-APH1B complexes with respective IC50
Formule :C₂₀H₁₉ClF₃NO₃S
Couleur et forme :Solid
Masse moléculaire :445.88
Ref: TM-T79679
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Aβ-IN-7
Aβ-IN-7 (compound 5a) acts as a potent inhibitor of Aβ aggregation, stabilizing Aβ monomers at 50 μM concentration to prevent them from forming larger oligomers
Formule :C₁₄H₁₀N₂S
Couleur et forme :Solid
Masse moléculaire :238.31
Ref: TM-T78884
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Antipsychotic agent-2
Compound 11: potent antipsychotic, binds 5-HT1A/2A/2C, D2, H1 receptors; K is 56.6-1140 nM, BBB permeable.
Formule :C₂₂H₂₆FN₅O
Couleur et forme :Solid
Masse moléculaire :395.47
Ref: TM-T74798
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Furosemide sodium
CAS :
- 41733-55-5
Furosemide sodium: potent NKCC inhibitor, loop diuretic, treats heart failure, hypertension, edema, selective GABAA antagonist.
Formule :C₁₂H₁₀ClN₂NaO₅S
Degré de pureté :99.52% - >99.99%
Couleur et forme :Solid
Masse moléculaire :352.73
Ref: TM-T35336
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LtIA-F
LtIA-F, a fluorescent LtIA derivative, aids study of α3β2 nAChR's structure, distribution, and binding domain.
Formule :C₈₆H₁₂₁N₂₅O₂₂S₄
Couleur et forme :Solid
Masse moléculaire :1985.31
Ref: TM-T75355
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Arisugacin G
CAS :
- 261951-57-9
Arisugacin G, a microbial metabolite, is a structural analogue of Arisugacin A. Unlike its analogue, Arisugacin G does not exhibit activity against AChE (acetylcholinesterase).
Formule :C₂₇H₃₂O₅
Couleur et forme :Solid
Masse moléculaire :436.54
Ref: TM-TN9068
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4-Hydroxy MET
CAS :
- 77872-41-4
4-Hydroxy MET (4-HO-MET) is a tryptamine-based new psychoactive substance (NPS), structurally similar to the endogenous neurotransmitter serotonin. It has hallucinogenic properties that affect mood, movement, and cognitive functions.
Formule :C₁₃H₁₈N₂O
Couleur et forme :Solid
Masse moléculaire :218.3
Ref: TM-T203151
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p-MPPF
CAS :
- 155204-26-5
p-MPPF is a 5-HT antagonist that can be used to study neurological diseases.
Formule :C₂₅H₂₇FN₄O₂
Degré de pureté :99.92%
Couleur et forme :Solid
Masse moléculaire :434.51
Ref: TM-T69750L
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8-Aminoadenine
CAS :
- 28128-33-8
8-Aminoadenine (7H-purine-6,8-diamine) is a ligand for Adenine Receptor with Ki of 0.0341 μM.
Formule :C₅H₆N₆
Degré de pureté :99.82%
Couleur et forme :Solid
Masse moléculaire :150.14
Ref: TM-T22013
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Pellotine
CAS :
- 19622-05-0
Pellotine is an alkaloid isolated from Lophophora. It acts as an inverse agonist of the 5-HT7 receptor (5-HT7 receptor), with an EC50 of 291 nM. Pellotine shows strong affinity for the 5-HT1DR and 5-HT6R, with Ki values of 117 nM and 170 nM, respectively. Additionally, Pellotine reduces intracellular cAMP levels, thereby decreasing neuronal excitability and neurotransmitter release.
Formule :C₁₃H₁₉NO₃
Couleur et forme :Solid
Masse moléculaire :237.295
Ref: TM-TN9164
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BChE-IN-39
BChE-IN-39 (Compound 7c) selectively inhibits butyrylcholinesterase (BChE) with an IC50 of 0.08 μM, while showing an IC50 of 3.98 μM for acetylcholinesterase (AChE) inhibition. Additionally, BChE-IN-39 downregulates GSK-3β expression, thereby inhibiting the excessive phosphorylation of tau protein.
Formule :C₂₉H₂₃ClFN₃O₃
Couleur et forme :Solid
Masse moléculaire :515.963
Ref: TM-T204121
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Octamylamine
CAS :
- 502-59-0
Octamylamine is a bioactive chemical.
Formule :C₁₃H₂₉N
Couleur et forme :Solid
Masse moléculaire :199.3761
Ref: TM-T33778
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Chrodrimanin B
CAS :
- 132196-54-4
Chrodrimanin B is a useful organic compound for research related to life sciences. The catalog number is T126052 and the CAS number is 132196-54-4.
Formule :C₂₇H₃₂O₈
Couleur et forme :Solid
Masse moléculaire :484.545
Ref: TM-T126052
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LY 344864 racemate
CAS :
- 186543-64-6
LY 344864 racemate is a 5-HT1F receptor agonist.
Formule :C₂₁H₂₂FN₃O
Degré de pureté :99.75%
Couleur et forme :Soild
Masse moléculaire :351.42
Ref: TM-T2344L
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Methoxy-X04
CAS :
- 863918-78-9
Methoxy-X04, a derivative of Congo red and Chrysamine-G, is a brain-permeable fluorescent probe for amyloid-β (Aβ).
Formule :C₂₃H₂₀O₃
Degré de pureté :98.96%
Couleur et forme :Solid
Masse moléculaire :344.4
Ref: TM-T22972
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Isobutyryl-L-carnitine
CAS :
- 25518-49-4
Isobutyryl-L-carnitine is a member of the class of compounds known as acylcarnitines. Isobutyryl-L-carnitine is a product of the acyl-CoA dehydrogenases.
Formule :C₁₁H₂₁NO₄
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :231.29
Ref: TM-T19381
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Fipronil sulfone
CAS :
- 120068-36-2
Fipronil sulfone is an insecticide fipronil. Its metabolite fipronil sulphone is an inhibitor of rat ɑ1β2γ2L GABA(A) receptor.
Formule :C₁₂H₄Cl₂F₆N₄O₂S
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :453.14
Ref: TM-T21071
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12,14-Dichlorodehydroabietic acid
CAS :
- 65281-77-8
12,14-Dichlorodehydroabietic acid activates BK channels, blocks GABA A receptors, and increases calcium and neurotransmitter release.
Formule :C₂₀H₂₆Cl₂O₂
Couleur et forme :Solid
Masse moléculaire :369.33
Ref: TM-T40750
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β-Amyloid (12-20)
CAS :
- 134649-29-9
β-Amyloid (12-20) is a peptide fragment of β-Amyloid.Thsis peptide contain the amino acid residues VFF at position (18-20), suggesting that this triad has
Formule :C₅₇H₈₃N₁₅O₁₁
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :1154.36
Ref: TM-TP1480
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VVZ-149
VVZ-149 is an antagonist of both serotonin receptor 2A (5HT2A) and glycine transporter type 2 (GlyT2), with potential anti-nociceptive activity.
Couleur et forme :Solid
Ref: TM-T35087
+ Info
Serazapine
CAS :
- 115313-22-9
Serazapine is a highly specific serotonin (5-HT2) binding inhibitor with anxiolytic activity for the treatment of anxiety disorders.
Formule :C₂₂H₂₃N₃O₂
Degré de pureté :98.71% - 99.57%
Couleur et forme :Solid
Masse moléculaire :361.44
Ref: TM-T68142
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Zalospirone
CAS :
- 114298-18-9
Zalospirone is a 5-HT1A receptor agonist that can be used to study anxiety disorders and major depressive disorder.
Formule :C₂₄H₂₉N₅O₂
Degré de pureté :98.41% - 99.82%
Couleur et forme :Solid
Masse moléculaire :419.52
Ref: TM-T68172
+ Info
K1833
K1833 is an inhibitor and reactivator of human acetylcholinesterase (hrAChE), exhibiting an inhibition concentration (IC50) of 58$.
Couleur et forme :Odour Solid
Ref: TM-T81998
+ Info
Ethylpropyltryptamine
CAS :
- 850032-68-7
Ethylpropyltryptamine (EPT) is an orally active novel psychoactive substance. It is predicted to act as a partial agonist of the 5-HT2A receptor.
Formule :C₁₅H₂₂N₂
Couleur et forme :Solid
Masse moléculaire :230.35
Ref: TM-T203137
+ Info
SQ-3
SQ-3, a quinoline analogue, prefers α-syn (Ki=39.3nM) to Aβ (Ki=230nM), and [18F]SQ3 is a lead for α-syn probes. [1]
Formule :C₂₁H₂₁FN₂O
Couleur et forme :Solid
Masse moléculaire :336.4
Ref: TM-T74974
+ Info
MGS0028
CAS :
- 321963-33-1
MGS0028 is a selective agonist of metabotropic glutamate 2/3 receptor, it could reverse abnormal behaviors in mice induced by isolation rearing.
Formule :C₈H₈FNO₅
Couleur et forme :Solid
Masse moléculaire :217.15
Ref: TM-T28033
+ Info
Trontinemab
CAS :
- 2568868-35-7
Trontinemab, a bispecific humanized IgG1-κ antibody, targets the amyloid beta A4 precursor protein (APP) and transferrin receptor p90, CD71 (TFRC).
Degré de pureté :96.77% - 99%
Couleur et forme :Liquid
Ref: TM-T80622
+ Info
Azocarnil
Azocarnil is a GABAergic agonist-enhancer used in neurological system research.
Couleur et forme :Odour Solid
Ref: TM-T200561
+ Info
FFN246
CAS :
- 2210244-83-8
FFN246, a fluorescent probe, concurrently targets the serotonin transporter (SERT) and vesicular monoamine transporter 2 (VMAT2), exhibiting excitation and
Formule :C₁₅H₁₃FN₂O
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :256.27
Ref: TM-T78684
+ Info
β-Secretase Inhibitor II
CAS :
- 263563-09-3
β-Secretase Inhibitor II is a tripeptide aldehyde compound that acts as an inhibitor of β-Secretase.
Formule :C₂₅H₃₉N₃O₅
Couleur et forme :Solid
Masse moléculaire :461.59
Ref: TM-T40260
+ Info
Epiboxidine hydrochloride
CAS :
- 862909-67-9
Epiboxidine HCl: potent α4β2 nAChR agonist; Ki 0.46 nM (rat), 1.2 nM (human); Epibatidine analog.
Formule :C₁₀H₁₅ClN₂O
Couleur et forme :Solid
Masse moléculaire :214.69
Ref: TM-T74131
+ Info
Atracurium
CAS :
- 64228-79-1
Atracurium (BW-33A) is a competitive AChR antagonist and non-depolarizing muscle relaxant that may cause bronchoconstriction.
Formule :C₅₃H₇₂N₂O₁₂₂
Couleur et forme :Solid
Masse moléculaire :929.14
Ref: TM-T75283
+ Info
RAGE antagonist peptide
CAS :
- 1092460-91-7
RAGE antagonist blocks S100P/A4, HMGB-1; hinders glioma growth, metastasis; reduces PDAC cell growth, NF-κB activity; counters TDI effects in mice.
Formule :C₅₇H₁₀₁N₁₃O₁₇S
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :1272.56
Ref: TM-TP1935
+ Info
ECPLA
CAS :
- 2349367-50-4
ECPLA is an LSD analog and a potent 5-HT2A agonist (EC50 of 14.6 nM), capable of stimulating Gq-mediated calcium flux. It exhibits high affinity for most serotonin receptors, α2-adrenergic receptors, and D2-like dopamine receptors.
Formule :C₂₁H₂₅N₃O
Couleur et forme :Solid
Masse moléculaire :335.44
Ref: TM-T203569
+ Info
Bleformin A
CAS :
- 1980064-35-4
Bleformin A, a natural BChE inhibitor from Bletilla striata, has a 5.2 μM IC50 and is studied for Alzheimer's research.
Formule :C₂₃H₂₀O₅
Couleur et forme :Solid
Masse moléculaire :376.4
Ref: TM-T75512
+ Info
Small Cardioactive Peptide B (SCPB)
CAS :
- 84746-43-0
SCPB: neurally active peptide, boosts adenylate cyclase in heart/gills, EC50s: 0.1 μM (heart), 1.0 μM (gills).
Formule :C₅₂H₈₀N₁₄O₁₁S₂
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :1141.41
Ref: TM-TP1844
+ Info
Ro 12-5637
CAS :
- 64544-24-7
Ro 12-5637 is a metabolite of moclobemide.
Formule :C₁₃H₁₇ClN₂O₃
Couleur et forme :Solid
Masse moléculaire :284.74
Ref: TM-T34345
+ Info
Osmanthuside B
CAS :
- 94492-23-6
Osmanthuside B, isolated from Pseuderanthemum carruthersii (Seem.) Guill.
Formule :C₂₉H₃₆O₁₃
Couleur et forme :Solid
Masse moléculaire :592.59
Ref: TM-T80009
+ Info
Antidepressant agent 4
Antidepressant agent 4: orally active, has antidepressant, anxiolytic, and nootropic effects.
Formule :C₁₉H₃₈ClN₅O₂S
Couleur et forme :Solid
Masse moléculaire :436.06
Ref: TM-T75003
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α-Conotoxin AuIB
CAS :
- 216299-21-7
Selective antagonist of α3β4 nicotinic acetylcholine receptors.
Formule :C₆₅H₈₉N₁₇O₂₁S₄
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :1572.76
Ref: TM-TP2061
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β-Secretase Inhibitor I
CAS :
- 1818239-19-8
β-Secretase Inhibitor I is a highly potent inhibitor of the β-secretase enzyme.
Formule :C₁₈H₁₈F₃N₅O₂S
Couleur et forme :Solid
Masse moléculaire :425.43
Ref: TM-T39251
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Fabesetron
CAS :
- 129300-27-2
Fabesetron (FK1052): oral dual antagonist for 5-HT3/5-HT4 receptors. Aids in managing acute and delayed chemo-induced emesis.
Formule :C₁₈H₁₉N₃O
Couleur et forme :Solid
Masse moléculaire :293.37
Ref: TM-T38692
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HDAC6-IN-49
HDAC6-IN-49 (Compound 3) is an inhibitor of HDAC, with IC50 values of 0.012 and 0.735 µM against HDAC6 and HDAC1, respectively. Additionally, it inhibits MAO-B, cholinesterase (ChE), histamine receptor (H3R), and serotonin 6 receptor (5-HT6R). HDAC6-IN-49 exhibits neuroprotective effects in SH-SY5Y cells and enhances cognitive functions and motor abilities in fruit fly models of Parkinson's disease and C. elegans models of Alzheimer's disease.
Couleur et forme :Odour Solid
Ref: TM-T200554
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AChE-IN-4
AChE-IN-4 is an acetylcholine esterase inhibitor (AChEI) with an IC50 value of 24.1 μM.
Formule :C₃₂H₂₅BrN₆O₄S
Couleur et forme :Solid
Masse moléculaire :669.55
Ref: TM-T74382
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RS 56812
CAS :
- 143137-37-5
RS 56812 is a 5-HT3 receptor antagonist and agonist used in the study of cognitive disorders.
Formule :C₁₈H₂₁N₃O₂
Degré de pureté :99.38%
Couleur et forme :Soild
Masse moléculaire :311.38
Ref: TM-T23264L
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β-Amyloid (1-17)
CAS :
- 186319-72-2
This synthetic peptide consists of amino acids 1 to 17 of beta amyloid protein. This peptide can be employed in beta amyloid solubility studies.
Formule :C₉₀H₁₃₀N₂₈O₂₉
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :2068.2
Ref: TM-TP1500
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ALEPH hydrochloride
CAS :
- 61638-08-2
ALEPH (hydrochloride) acts as a partial agonist of h5-HT2A and h5-HT2B receptors, with EC50 values of 10.3 nM and 19.2 nM, respectively. It can induce head twitch responses in mice, with an ED50 of 0.80 mg/kg.
Formule :C₁₂H₂₀ClNO₂S
Couleur et forme :Solid
Masse moléculaire :277.81
Ref: TM-T203157
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Antidepressant agent 3
Agent 3: orally active, antidepressant, anxiolytic, boosts performance and cognition.
Formule :C₁₇H₃₀ClN₅O₂S
Couleur et forme :Solid
Masse moléculaire :403.97
Ref: TM-T75002
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β-Amyloid (1-20)
CAS :
- 186319-68-6
This synthetic peptide consists of amino acids 1 to 20 of beta amyloid protein.
Formule :C₁₁₃H₁₅₇N₃₁O₃₂
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :2461.7
Ref: TM-TP1538
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SIB 1553A
CAS :
- 191611-76-4
SIB 1553A is an agonist of nAChRs, a cognitive enhancer that can be used to study diseases associated with neurodegeneration.
Formule :C₁₃H₁₉NOS
Degré de pureté :99.79%
Couleur et forme :Soild
Masse moléculaire :237.36
Ref: TM-T16881L
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Stacofylline
CAS :
- 98833-92-2
Stacofylline is a xanthine derivative that is used to treat migraine headaches.
Formule :C₂₀H₃₃N₇O₃
Degré de pureté :99.54% - >99.99%
Couleur et forme :Solid
Masse moléculaire :419.52
Ref: TM-T68145
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(S)-UFR2709 hydrochloride
CAS :
- 2934318-93-9
(S)-UFR2709 HCl: competitive nAChR blocker, prefers α4β2 over α7, lessens anxiety & alcohol intake in rats, studies nicotine addiction.
Formule :C₁₃H₁₈ClNO₂
Degré de pureté :98.94%
Couleur et forme :Solid
Masse moléculaire :255.74
Ref: TM-T37094
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Velnacrine
CAS :
- 124027-47-0
Velnacrine (1,2,3,4-tetrahydro-9-aminoacridin-1-ol maleate) is a biochemical.
Formule :C₁₃H₁₄N₂O
Degré de pureté :99.83%
Couleur et forme :Solid
Masse moléculaire :214.26
Ref: TM-T35045
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Deoxynojirimycin Tetrabenzyl Ether
CAS :
- 69567-11-9
Deoxynojirimycin tetrabenzyl ether aids in making 1-dNM, a strong α-glucosidase I & II blocker.
Formule :C₃₄H₃₇NO₄
Couleur et forme :Solid
Masse moléculaire :523.673
Ref: TM-T37903
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MAO-B-IN-38
MAO-B-IN-38 (Compound 6b) is a reversible, competitive inhibitor of MAO-B, exhibiting IC50 values of 0.03 µM for MAO-B and 21.46 µM for MAO-A. This compound is applicable in research on neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease.
Formule :C₁₄H₁₇FN₄O₂S₃
Couleur et forme :Solid
Masse moléculaire :388.504
Ref: TM-T204375
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Neocarzinostatin
CAS :
- 9014-02-2
Neocarzinostatin is an effective DNA-damaging, anti-tumor antibiotic.
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :N/A
Ref: TM-T16283
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5-MeO-pyr-T
CAS :
- 3949-14-2
5-MeO-pyr-T (5-Methoxy pyrrolidinyltryptamine) acts as a 5-HT1AR agonist, exhibiting Ki values of 0.577 μM and 373 μM for 5-HT1AR and 5-HT2AR, respectively. It inhibits the reuptake of 5-HT and triggers its release. Additionally, 5-MeO-pyr-T can induce reduced motor activity.
Formule :C₁₅H₂₀N₂O
Couleur et forme :Solid
Masse moléculaire :244.33
Ref: TM-T203568
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Adatanserin hydrochloride
CAS :
- 144966-96-1
Adatanserin hydrochloride (WY50324 hydrochloride) is a 5-HT(1A)/5-HT(2) receptor ligand that is neuroprotective and may be used in the study of depression.
Formule :C₂₁H₃₂ClN₅O
Degré de pureté :99.64%
Couleur et forme :Solid
Masse moléculaire :405.96
Ref: TM-T29645
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Camlipixant
CAS :
- 1621164-74-6
Camlipixant (BLU-5937) is an orally active purine P2X3 receptor antagonist that is potent, selective and competitive.
Formule :C₂₃H₂₄F₂N₄O₄
Degré de pureté :99.37%
Couleur et forme :Soild
Masse moléculaire :458.46
Ref: TM-T67885
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C175-0062
CAS :
- 686736-69-6
C175-0062, a monoamine oxidase B (MAO-B) inhibitor, is applicable in research focused on neurodegenerative disorders such as Parkinson's disease (PD), Alzheimer's disease (AD), and amyotrophic lateral sclerosis (ALS) [1].
Formule :C₂₁H₁₈N₂O₅
Couleur et forme :Solid
Masse moléculaire :378.38
Ref: TM-T85985
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Tiflucarbine
CAS :
- 89875-86-5
Tiflucarbine is a potential non-selective 5-HT agonist with antidepressant activity.Tiflucarbine dose-dependently increased the specific activity of soluble
Formule :C₁₆H₁₇FN₂S
Degré de pureté :>99.99%
Couleur et forme :Solid
Masse moléculaire :288.38
Ref: TM-T68162
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Orexin A (human, rat, mouse) acetate
Orexin A (human, rat, mouse) acetate (Hypocretin-1 (human, rat, mouse) acetate) is an excitatory neuropeptide with analgesic properties.
Formule :C₁₅₄H₂₄₇N₄₇O₄₆S₄
Couleur et forme :Solid
Masse moléculaire :3621.15
Ref: TM-T73658
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Pomaglumetad methionil anhydrous
CAS :
- 635318-55-7
LY2140023, potential schizophrenia treatment, is an oral prodrug of LY404039, a selective mGlu2/3 agonist.
Formule :C₁₂H₁₈N₂O₇S₂
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :366.41
Ref: TM-T11907
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Donitriptan hydrochloride
CAS :
- 170911-68-9
Donitriptan hydrochloride (Donitriptan monohydrochloride) is a potent, high efficacy agonist of 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectively
Formule :C₂₃H₂₆ClN₅O₂
Degré de pureté :99.8% - 99.86%
Couleur et forme :Solid
Masse moléculaire :439.94
Ref: TM-T21666
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bPiDDB
CAS :
- 525596-66-1
bPiDDB (N,N'-Dodecylbis-Picolinium Bromide) is a nicotinic receptor (nAChR) antagonist.
Formule :C₂₄H₃₈Br₂N₂
Degré de pureté :98.72%
Couleur et forme :Solid
Masse moléculaire :514.38
Ref: TM-T37818
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(±)-Acetylcarnitine chloride
CAS :
- 2504-11-2
(±)-Acetylcarnitine chloride (Acetyl dl-carnitine chloride) is a weak cholinergic agonist with neuroprotective properties and can be used in studies of neuritis.
Formule :C₉H₁₈ClNO₄
Degré de pureté :99.98%
Couleur et forme :White Crystalline Powder
Masse moléculaire :239.7
Ref: TM-T21655
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TC-2559 difumarate
CAS :
- 2454492-41-0
TC-2559 difumarate: Oral α4β2 nAChR partial agonist, CNS-selective, EC50 0.18 μM, prefers α4β2 over α2β4/α4β4/α3β4, antinociceptive.
Formule :C₂₀H₂₆N₂O₉
Couleur et forme :Solid
Masse moléculaire :438.43
Ref: TM-T40119
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JNJ-67569762
CAS :
- 2380313-26-6
JNJ-67569762 is a selective BACE1 inhibitor targeting the S3 pocket ( IC 50 = 2.7 nM).
Formule :C₂₂H₂₂F₄N₄O₅S
Couleur et forme :Solid
Masse moléculaire :530.49
Ref: TM-T39955
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Brexanolone caprilcerbate
CAS :
- 2681264-65-1
Brexanolone caprilcerbate is an effective positive allosteric modulator of the GABAA receptor.
Formule :C₄₈H₇₈O₁₂
Couleur et forme :Solid
Masse moléculaire :847.13
Ref: TM-T200857
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AChE/BChE-IN-22
AChE/BChE-IN-22 (compound 7) exhibits competitive inhibition against both AChE and BChE enzymes, with inhibition constants of 28.18 μM and 41.74 μM respectively.
Formule :C₁₄H₁₁F₃N₂O₄S
Couleur et forme :Solid
Masse moléculaire :360.31
Ref: TM-T201151
+ Info
Exosome Compound Library
76 exosome-related compounds that can be used for high-throughput and high-content screening.
Couleur et forme :Odour Solid
Ref: TM-L9420
+ Info
C18 L-erythro Ceramide (d18:1/18:0)
CAS :
- 252039-52-4
C18 L-erythro Ceramide, a natural stereoisomer, inhibits rat brain mt-CDase with IC50 of 8.8 μM.
Formule :C₃₆H₇₁NO₃
Couleur et forme :Solid
Masse moléculaire :565.95
Ref: TM-T37456
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β-Amyloid (1-34)
CAS :
- 186359-65-9
This is a fragment of beta-amyloid peptide. It has amino acids 1 through 34.
Formule :C₁₇₀H₂₅₃N₄₇O₅₂
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :3787.2
Ref: TM-TP1599
+ Info
N-Methylcyclohexaneethaneamine
CAS :
- 62141-38-2
N-Methylcyclohexaneethaneamine is a useful organic compound for research related to life sciences.
Formule :C₉H₁₉N
Couleur et forme :Solid
Masse moléculaire :141.2539
Ref: TM-T124533
+ Info
PF-03382792
CAS :
- 1400811-63-3
PF-03382792 is a small molecule 5-HT4 receptor activator for the study of Alzheimer's disease.
Formule :C₂₃H₃₂FN₃O₄
Degré de pureté :99.64%
Couleur et forme :Solid
Masse moléculaire :433.52
Ref: TM-T33940
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Isonaringin
CAS :
- 108815-81-2
Isonaringin shows anti-Alzheimer’s activity by inhibiting AChE.
Formule :C₂₇H₃₂O₁₄
Couleur et forme :Solid
Masse moléculaire :580.53
Ref: TM-T38477
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Soclenicant
CAS :
- 1020634-41-6
Soclenicant is a negative-altering modulator of α 7 -nAChR for anxiety, depression, and PTSD, due to its high selectivity, oral availability
Formule :C₂₄H₂₆N₄O₃
Degré de pureté :99.57%
Couleur et forme :Soild
Masse moléculaire :418.49
Ref: TM-T203814
+ Info
Potassium Channel Targeted Library
A unique collection of xnum potassium channel blockers and agonists for high throughput and high content screening;
Couleur et forme :Odour Solid
Ref: TM-L7300
+ Info
CP 465022
CAS :
- 199655-36-2
CP 465022 hydrochloride is a potent AMPA receptor antagonist with anti-seizure properties, inhibiting responses at an IC50 of 25 nM.
Formule :C₂₆H₂₄ClFN₄O
Degré de pureté :99.05%
Couleur et forme :Solid
Masse moléculaire :462.95
Ref: TM-T21584
+ Info
Bis-(-)-8-demethylmaritidine
Bis-(-)-8-demethylmaritidine, a natural alkaloid, serves as a potent inhibitor of acetylcholinesterase (AChE) and is utilized in Alzheimer's disease research [1
Couleur et forme :Odour Solid
Ref: TM-T82861
+ Info
Histamine & Melatonin Receptor-Targeted Compound Library
A unique collection of xnum compounds targeting histaminergic receptor and melatonin receptor for high throughput screening (HTS) and high content screening (HCS
Couleur et forme :Odour Solid
Ref: TM-L3300
+ Info
Fezolamine
CAS :
- 80410-36-2
Fezolamine: a new, non-tricyclic, oral antidepressant, selectively inhibits norepinephrine uptake over serotonin or dopamine.
Formule :C₂₀H₂₃N₃
Degré de pureté :99.33%
Couleur et forme :Solid
Masse moléculaire :305.42
Ref: TM-T68070
+ Info
Neurotransmitter Receptor Compound Library
A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening；
Couleur et forme :Odour Solid
Ref: TM-L2610
+ Info
DCCCyb
CAS :
- 1236046-15-3
DCCCyb: oral GlyT1 inhibitor with high in vivo occupancy in rhesus monkeys, confirmed by PET tracer displacement.
Formule :C₂₂H₂₉Cl₂NO₃S
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :458.44
Ref: TM-T25292
+ Info
M4 mAChR agonist-1
CAS :
- 785705-53-5
M4 mAChR agonist-1 (4-Piperidinecarboxamide, 1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)-) is an effective agonist of M4 mAChR (EC50 >10 μM).
Formule :C₁₄H₁₈N₄OS
Degré de pureté :99.14%
Couleur et forme :Solid
Masse moléculaire :290.38
Ref: TM-T9889
+ Info
(S)-AMPA HCl
(S)-AMPA HCl (L-AMPA HCl) is a selective AMPA receptor agonist with potential antidepressant activity. It can be used in research on Parkinson's disease.
Formule :C₇H₁₁ClN₂O₄
Degré de pureté :99.18%
Couleur et forme :Solid
Masse moléculaire :222.63
Ref: TM-T21271L
+ Info
Serotonin Receptor-Targeted Compound Library
A unique collection of xnum compounds targeting serotonin receptors for high throughput screening and high content screening;
Couleur et forme :Odour Solid
Ref: TM-L2800
+ Info
LE 300
CAS :
- 274694-98-3
LE 300 represents a structurally novel type of antagonists acting preferentially at the dopamine D(1)/D(5)receptors and the serotonin 5-HT(2A)receptor.
Formule :C₂₀H₂₂N₂
Degré de pureté :97.91% - 98.79%
Couleur et forme :Solid
Masse moléculaire :290.4
Ref: TM-T22921
+ Info
Ion Channel Targeted Library
A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;
Couleur et forme :Odour Solid
Ref: TM-L2300
+ Info
Calcium Channel Compound Library
A unique collection of 140 calcium channel blockers and agonists for high throughput and high content screening;
Couleur et forme :Odour Solid
Ref: TM-L7200
+ Info
Tryptamine hydrochloride
CAS :
- 343-94-2
Tryptamine hydrochloride is a monoamine alkaloid, metabolite of tryptophan and CNS active substance, agonist of 5-HT4 receptor, TAAR1, AHR.
Formule :C₁₀H₁₃ClN₂
Degré de pureté :99.89%
Couleur et forme :Solid
Masse moléculaire :196.68
Ref: TM-T124997
+ Info
R 50595
CAS :
- 104860-61-9
R 50595 is a selective non-competitive cisapride antagonist.
Formule :C₃₀H₃₅Cl₂F₂N₃O₃
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :594.52
Ref: TM-T26015
+ Info
CNS-Penetrant Compound Library
A unique collection of 509 CNS-Penetrant compounds for high throughput screening (HTS) and high content screening (HCS);
Couleur et forme :Odour Solid
Ref: TM-L5900
+ Info
Tariquidar methanesulfonate hydrate
CAS :
- 625375-83-9
m-PEG8-Ms is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC compounds.
Formule :C₄₀H₅₈N₄O₁₈S₂
Degré de pureté :98.13%
Couleur et forme :Solid
Masse moléculaire :947.04
Ref: TM-T13087
+ Info
Neural Regeneration Compound Library
A unique collection of 149 neuroregeneration related compounds for high throughput and high content screening;
Couleur et forme :Odour Solid
Ref: TM-L7700
+ Info
Hamaline
CAS :
- 2411677-02-4
Hamaline (9-(4-chlorobenzyl)-6-methoxy-1-methyl-4,9-dihydro-3H-pyrido[3,4-b]indole) is a substrate-selective cyclooxygenase-2 (COX-2) inhibitor.
Formule :C₂₀H₁₉ClN₂O
Degré de pureté :99.88%
Couleur et forme :Soild
Masse moléculaire :338.83
Ref: TM-T60053
+ Info
ACHE Inhibitor 12
CAS :
- 66309-83-9
ACHE Inhibitor 12 inhibited acetylcholinesterase with an IC50 value of 0.38 µM.
Formule :C₁₁H₁₂O
Degré de pureté :98.71%
Couleur et forme :Solid
Masse moléculaire :160.21
Ref: TM-T77352
+ Info
Minesapride
CAS :
- 1184662-54-1
Minesapride: novel 5-HT4 partial agonist, may treat constipation-predominant IBS.
Formule :C₂₁H₃₁ClN₄O₅
Degré de pureté :99.85% - 99.88%
Couleur et forme :Solid
Masse moléculaire :454.95
Ref: TM-T28043L
+ Info
Apoptosis Compound Library
A unique collection of 1760 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening;
Couleur et forme :Odour Solid
Ref: TM-L9000
+ Info
(+)-OSU 6162
CAS :
- 160777-43-5
(+)-OSU 6162 (Piperidine, 3-[3-(methylsulfonyl)phenyl]-1-propyl-, (3R)-) is an agonist of 5-HT Receptor with anti-Alzheimer and antidepressant activities.
Formule :C₁₅H₂₃NO₂S
Degré de pureté :98.19%
Couleur et forme :Soild
Masse moléculaire :281.41
Ref: TM-T60027
+ Info
1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-
CAS :
- 175340-21-3
1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)- is a low activity isomer of S 18986.
Formule :C₁₀H₁₂N₂O₂S
Degré de pureté :99.96%
Couleur et forme :Soild
Masse moléculaire :224.28
Ref: TM-T60224
+ Info
Aducanumab
CAS :
- 1384260-65-4
Aducanumab (BIIB037) is an IgG1 antibody targeting amyloid beta to treat Alzheimer's; it's brain-permeable.
Degré de pureté :95% - 97.10%
Couleur et forme :Liquid
Masse moléculaire :145.93 kDa
Ref: TM-T77042
+ Info
BIBD-124
CAS :
- 2716871-93-9
BIBD-124, with an IC50 value of 9.51 nM, effectively binds to amyloid beta (Aβ) plaques.
Formule :C₁₉H₂₄FN₃O₃
Couleur et forme :Solid
Masse moléculaire :361.41
Ref: TM-T74786
+ Info
Pemedolac
CAS :
- 114716-16-4
Pemedolac (Dexpemedolac) is a small molecule COX inhibitor used to treat neurological disorders, skin and musculoskeletal disorders.
Formule :C₂₂H₂₃NO₃
Degré de pureté :>99.99%
Couleur et forme :Solid
Masse moléculaire :349.42
Ref: TM-T68126
+ Info
3-Aminopropylphosphonic Acid
CAS :
- 13138-33-5
3-aminopropylphosphonic acid (3-APPA) is a phosphonic analog of GABA that acts as a partial agonist of GABAB receptors (IC50 = 1.5 μM in a radioligand binding
Formule :C₃H₁₀NO₃P
Degré de pureté :99.84%
Couleur et forme :Light Yellow Liquid
Masse moléculaire :139.09
Ref: TM-T38205
+ Info
MK-0969
CAS :
- 203321-88-4
MK-0969 (J-104135) is a possible M3 antagonist for the treatment of chronic obstructive pulmonary disease.
Formule :C₂₄H₃₀F₂N₄O₂
Couleur et forme :Solid
Masse moléculaire :444.52
Ref: TM-T33425
+ Info
5H-Pyrido[4,3-b]indole
CAS :
- 244-69-9
5H-Pyrido[4,3-b]indole is a potential AchE/ChE inhibitor with potential antiviral activity for the study of neurodegenerative diseases.
Formule :C₁₁H₈N₂
Degré de pureté :99.6%
Couleur et forme :Solid
Masse moléculaire :168.2
Ref: TM-TN9455
+ Info
Neuronal Signaling Compound Library
A unique collection of xnum compounds targeting CNS signaling for high throughput screening (HTS) and high content screening (HCS) for new drugs;
Couleur et forme :Odour Solid
Ref: TM-L2600
+ Info
β-Amyloid (22-40)
CAS :
- 1206779-25-0
This synthetic peptide consists of amino acids 22 to 40 of beta amyloid protein.
Formule :C₇₈H₁₃₅N₂₁O₂₆S
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :1815.1
Ref: TM-TP1544
+ Info
Xaliproden
CAS :
- 135354-02-8
Xaliproden is a biochemical.
Formule :C₂₄H₂₂F₃N
Couleur et forme :Solid
Masse moléculaire :381.43
Ref: TM-T35152
+ Info
ACG548B
CAS :
- 795316-16-4
ACG548B inhibits AChE/BChE with IC50s of 1.78/0.496 μM; favors AChE over BChE/ChoK.
Formule :C₃₈H₃₄Br₂Cl₂N₄
Couleur et forme :Solid
Masse moléculaire :777.43
Ref: TM-T40904
+ Info
Atagabalin
CAS :
- 223445-75-8
Atagabalin (PD 0200390), a gabamimetic for insomnia treatment and related to gabapentin, was halted due to poor trial outcomes.
Formule :C₁₀H₁₉NO₂
Couleur et forme :Solid
Masse moléculaire :185.26
Ref: TM-T30188
+ Info
(S,S)-BMS-984923
CAS :
- 1375752-77-4
(S,S)-BMS-984923 is a weak mGluR5 modulator with EC50 >1μM; less active than its potent counterpart.
Formule :C₂₂H₁₅ClN₂O₂
Couleur et forme :Solid
Masse moléculaire :374.82
Ref: TM-T74185
+ Info
ANQ-9040
CAS :
- 142021-80-5
ANQ-9040 is a nondepolarizing neuromuscular relaxant of the steroid class.
Formule :C₃₆H₅₈N₂O₅S
Couleur et forme :Solid
Masse moléculaire :630.92
Ref: TM-T30079
+ Info
5-Hydroxymethyl tolterodine formate
CAS :
- 380636-49-7
5-Hydroxymethyl tolterodine (formate) (PNU-200577 (formic)) is an active metabolite of the muscarinic acetylcholine receptor antagonists Tolterodine and Fesoterodine. It is synthesized by the cytochrome P450 (CYP) isoenzyme CYP2D6 and plasma esterases.
Formule :C₂₃H₃₃NO₄
Couleur et forme :Solid
Masse moléculaire :387.51
Ref: TM-T203543
+ Info
Dapoxetine
CAS :
- 119356-77-3
Dapoxetine (Dapoxetina) is a selective serotonin reuptake inhibitor, for the treatment of premature ejaculation.
Formule :C₂₁H₂₃NO
Degré de pureté :99.73%
Couleur et forme :White To Off-White Crystalline Powder
Masse moléculaire :305.42
Ref: TM-T0039
+ Info
Methyl ganoderate A acetonide
CAS :
- 1346453-53-9
Methyl ganoderate A from Ganoderma lucidum is a natural AChE inhibitor (IC50=18.35 μM) for Alzheimer's research.
Formule :C₃₄H₅₀O₇
Couleur et forme :Solid
Masse moléculaire :570.76
Ref: TM-T75628
+ Info
OXA(17-33)
CAS :
- 343268-91-7
Potent and selective peptide orexin OX1 receptor agonist (EC50 values are 8.29 and 187 nM for OX1 and OX2 receptors respectively). Truncated form of orexin A.
Formule :C₇₉H₁₂₅N₂₃O₂₂
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :1749
Ref: TM-TP1973
+ Info
Amyloid-Forming peptide GNNQQNY
CAS :
- 339091-39-3
Amyloid-Forming peptide GNNQQNY, a biologically active heptapeptide derived from the N-terminal prion-determining domain of yeast Sup35, is instrumental in
Formule :C₃₃H₄₈N₁₂O₁₄
Couleur et forme :Solid
Masse moléculaire :836.81
Ref: TM-T83122
+ Info
Aceclidine (hydrochloride)
CAS :
- 6109-70-2
agonist of muscarinic receptors
Formule :C₉H₁₆ClNO₂
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :205.68
Ref: TM-T22544
+ Info
Sodium Channel Targeted Library
A unique collection of xnum sodium channel blockers and agonists for high throughput and high content screening;
Couleur et forme :Odour Solid
Ref: TM-L7400
+ Info
Coumarinic acid
CAS :
- 495-79-4
Coumarinic acid serves as a brain-penetrating inhibitor of AChE (acetylcholinesterase) and β-amyloid, with applications in anti-Alzheimer's drug research [1].
Formule :C₉H₈O₃
Couleur et forme :Solid
Masse moléculaire :164.16
Ref: TM-T79968
+ Info
LOX-IN-4
CAS :
- 2125956-92-3
LOX-IN-4 (Compound 112) is an inhibitor of lysyl oxidase (LOX). It holds potential for use in cancer research.
Formule :C₂₀H₂₄Cl₂FN₃O₂S
Couleur et forme :Solid
Masse moléculaire :460.39
Ref: TM-T203658
+ Info
(-)-Coclaurine hydrochloride
CAS :
- 3422-42-2
(-)-Coclaurine hydrochloride is an antagonist of nAChRs isolated from Sarcopetalum harveyanum.
Formule :C₁₇H₂₀ClNO₃
Degré de pureté :99.07%
Couleur et forme :Soild
Masse moléculaire :321.8
Ref: TM-TN1519L
+ Info
GABA-A Receptor Ligand-1
GABA-A Receptor Ligand-1 (Compound 4) is a ligand for the GABA-A receptor with a pKi of 7.27. It alleviates mitochondrial dysfunction, promotes neurite outgrowth and neuronal regeneration, and demonstrates neuroprotective effects in a rat ischemic stroke model.
Formule :C₂₀H₂₀FN₃O
Couleur et forme :Solid
Masse moléculaire :337.391
Ref: TM-T204750
+ Info
COX-2-IN-34
CAS :
- 2788578-71-0
COX-2-IN-34 is a selective, orally potent COX-2 inhibitor that shows anti-inflammatory activity without gastric ulcer toxicity during experiments in mice.
Formule :C₁₃H₁₁NO₄
Degré de pureté :98.08%
Couleur et forme :Soild
Masse moléculaire :245.23
Ref: TM-T77618
+ Info
Sabirnetug
CAS :
- 2747959-38-0
Sabirnetug is a humanized IgG2κ monoclonal antibody that specifically targets the amyloid-β (A4) precursor protein.
Couleur et forme :Liquid
Ref: TM-T80563
+ Info
(+)-Cinchonaminone
CAS :
- 60305-15-9
(+)-Cinchonaminone shows monoamine oxidase (MAO) inhibitory activity.
Formule :C₁₉H₂₄N₂O₂
Couleur et forme :Solid
Masse moléculaire :312.413
Ref: TM-T40689
+ Info
Rasagiline 13C3 mesylate racemic
CAS :
- 1216757-55-9
Rasagiline 13C3 mesylate racemic is the deuterium labeled Rasagiline, which is an irreversible monoamine oxidase inhibitor.
Formule :C₁₃H₁₇NO₃S
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :270.32
Ref: TM-T12693
+ Info
Anagyrine hydrochloride
CAS :
- 74195-83-8
Anagyrine hydrochloride, a quinolizidine from Lupinus albus, targets muscarinic/nicotinic receptors; IC50: 132/2096 µM. It desensitizes nAChR directly.
Formule :C₁₅H₂₁ClN₂O
Couleur et forme :Solid
Masse moléculaire :280.79
Ref: TM-T73856
+ Info
N-Ethyl-N-(3-pyridylmethyl)amine
CAS :
- 3000-75-7
N-Ethyl-N-(3-pyridylmethyl)amine has affinity for nAChR (Ki = 0.97 µM) and can be used in related research in the field of life sciences.
Formule :C₈H₁₂N₂
Degré de pureté :99.65%
Couleur et forme :Solid
Masse moléculaire :136.19
Ref: TM-TN9660
+ Info
Calmodulin-Dependent Protein Kinase II (281-309)
CAS :
- 116826-37-0
Calmodulin-Dependent Protein Kinase II (281-309) is a synthetic peptide that can be phosphorylated at Thr286 by PKC and inhibits CaM kinase II (IC50 = 80 nM).
Formule :C₁₄₆H₂₅₄N₄₆O₃₉S₃
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :3374.06
Ref: TM-TP1716
+ Info
Anticonvulsant agent 8
Anticonvulsant agent 8 (compound D4) is a chemical used in treating epilepsy by inhibiting GABAA currents. In mouse models, its ED50 values are 2.23 mg/kg for the maximal electroshock (MES) test and 24.60 mg/kg for the pentylenetetrazol (PTZ) test.
Formule :C₁₅H₁₁N₅O
Couleur et forme :Solid
Masse moléculaire :277.28
Ref: TM-T205302
+ Info
Emamectin B1a
CAS :
- 121124-29-6
Emamectin B1a can be used in relevant research in the life sciences. Its product number is T37663 and CAS number is 121124-29-6.
Formule :C₄₉H₇₅NO₁₃
Couleur et forme :Solid
Masse moléculaire :886.133
Ref: TM-T37663
+ Info
(R,R)-Palonosetron Hydrochloride
CAS :
- 135729-75-8
(R,R)-Palonosetron Hydrochloride is the active enantiomer of Palonosetron
Formule :C₁₉H₂₅ClN₂O
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :332.87
Ref: TM-T13437
+ Info
nAChR modulator-2
CAS :
- 1700657-87-9
nAChR modulator-2, a insecticide, is a insect nAChR orthosteric modulator [1] .
Formule :C₁₂H₈ClN₃O₂
Couleur et forme :Solid
Masse moléculaire :261.66
Ref: TM-T74397
+ Info
Biperiden Hydrochloride
CAS :
- 1235-82-1
Biperiden HCl is an anti-Parkinson's drug, blocks M1 receptors, manages all Parkinson's types, and is FDA-approved. Non-toxic at 0.11 mg/kg to rats' cognition.
Formule :C₂₁H₃₀ClNO
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :347.92
Ref: TM-T14614
+ Info
Oxotremorine
CAS :
- 70-22-4
Oxotremorine acts as an agonist of mAChR, specifically activating the M1 and M3 acetylcholine receptors. In drug discrimination experiments with macaques, it exhibits effects similar to nicotine.
Formule :C₁₂H₁₈N₂O
Couleur et forme :Solid
Masse moléculaire :206.28
Ref: TM-T203251
+ Info
Alverine hydrochloride
CAS :
- 5982-87-6
Alverine hydrochloride is a parasympatholytic.
Formule :C₂₀H₂₈ClN
Couleur et forme :Solid
Masse moléculaire :317.9
Ref: TM-T0428L
+ Info
25N-NBOMe hydrochloride
CAS :
- 1566571-65-0
25N-NBOMe hydrochloride is a derivative of 2C-N and acts as an agonist for the 5-HT2A and 5-HT2C receptors, with Ki values of 0.144 nM and 1.06 nM, respectively. It has minimal effect on the release of preloaded neurotransmitters from recombinant dopamine, serotonin, and norepinephrine transporters.
Formule :C₁₈H₂₃ClN₂O₅
Couleur et forme :Solid
Masse moléculaire :382.84
Ref: TM-T203235
+ Info
BuChE-IN-16
BuChE-IN-16 (Compound 6a) is an orally active, blood-brain barrier-permeable, and selective BuChE inhibitor with an IC50 of 0.33 μM. It exhibits anti-inflammatory and neuroprotective effects, improves cognitive function in Alzheimer's disease (AD) zebrafish models, and alleviates scopolamine-induced memory impairment in mice. BuChE-IN-16 is applicable for Alzheimer's disease research.
Formule :C₁₆H₂₂N₂O₃
Couleur et forme :Solid
Masse moléculaire :290.36
Ref: TM-T205388
+ Info
Encecalinol
CAS :
- 88728-56-7
Encecalinol, a compound isolated from the aerial parts of Ageratina grandifolia, acts as a potent inhibitor of calmodulin [1].
Formule :C₁₄H₁₈O₃
Couleur et forme :Solid
Masse moléculaire :234.29
Ref: TM-T82472
+ Info
BChE-IN-16
BChE-IN-16 (compound 87) is a potent inhibitor of human butyrylcholinesterase (hBChE) exhibiting an inhibition concentration half-maximum (IC50) of 3.8 nM.
Formule :C₂₈H₃₂FNO₂
Couleur et forme :Solid
Masse moléculaire :433.56
Ref: TM-T78695
+ Info
AMI-193
CAS :
- 510-74-7
AMI-193 (Spiramide) is a selective 5-HT2 & D2 receptor antagonist with antipsychotic properties.
Formule :C₂₂H₂₆FN₃O₂
Degré de pureté :99.65%
Couleur et forme :Solid
Masse moléculaire :383.46
Ref: TM-T21855
+ Info
β-Amyloid (10-35), amide
CAS :
- 181427-66-7
β-Amyloid (10-35), amide, is a chemical compound consisting of 26 amino acids, specifically residues 10-35 of the Aβ peptide.
Formule :C₁₃₃H₂₀₅N₃₅O₃₆S
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :2902.33
Ref: TM-TP1729
+ Info
Dipentylone hydrochloride
CAS :
- 17763-13-2
Dipentylone hydrochloride (Bk-dmbdp HCl) is a psychoactive synthetic cathinone and sympathomimetic stimulant. Its inhibitory activity towards the dopamine transporter (IC50=0.233µM) is tenfold higher than that towards NET and SERT, inhibiting dopamine uptake and stimulating locomotor activity in mice.
Formule :C₁₄H₂₀ClNO₃
Degré de pureté :99.94%
Couleur et forme :Solid
Masse moléculaire :285.77
Ref: TM-T205977
+ Info
(S)-Vamicamide
CAS :
- 151851-72-8
(S)-Vamicamide is an anti-anticholinergic compound.
Formule :C₁₈H₂₃N₃O
Degré de pureté :99.48% - 99.65%
Couleur et forme :Soild
Masse moléculaire :297.39
Ref: TM-T35033L
+ Info
2,3-Dehydrosilybin A
CAS :
- 25166-14-7
2,3-Dehydrosilybin A is a useful organic compound for research related to life sciences and the catalog number is T125202.
Formule :C₂₅H₂₀O₁₀
Couleur et forme :Solid
Masse moléculaire :480.425
Ref: TM-T125202
+ Info
Mirtazapine N-oxide
CAS :
- 155172-12-6
Mirtazapine N-oxide, a mirtazapine metabolite, is produced by CYP1A2 and CYP3A4 in human liver.
Formule :C₁₇H₁₉N₃O
Couleur et forme :Solid
Masse moléculaire :281.359
Ref: TM-T37430
+ Info
β-Amyloid (1-16)
CAS :
- 131580-10-4
β-Amyloid (1-16) is an amyloidogenic protein fragment with a sequence derived from β-amyloid.
Formule :C₈₄H₁₁₉N₂₇O₂₈
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :1955.04
Ref: TM-TP1228
+ Info
Riluzole-13C,15N2
CAS :
- 1215552-03-6
Riluzole-13C,15N2 (PK 26124-13C,15N2) is a 13C and 15N labeled form of Riluzole, a glutamate antagonist with anticonvulsant activity, inhibiting GABA uptake.
Formule :CC₇H₅F₃OS₁₅N₂
Couleur et forme :Solid
Masse moléculaire :237.18
Ref: TM-T37608
+ Info
4-Butyl-α-agarofuran
CAS :
- 272126-07-5
4-Butyl-alpha-agarofuran, a Gharu-wood derivative, is an anxiolytic, antidepressant, and aids neurological research.
Formule :C₁₈H₃₀O
Couleur et forme :Solid
Masse moléculaire :262.43
Ref: TM-T75257
+ Info
Chrysophanol-1-O-β-gentiobioside
CAS :
- 54944-38-6
Chrysophanol-1-O-β-gentiobioside, an anthraquinone glycoside obtained from the seeds of Cassia obtusifolia, exhibits targeted inhibition of hMAO-A isozyme
Formule :C₂₇H₃₀O₁₄
Couleur et forme :Solid
Masse moléculaire :578.52
Ref: TM-T40628
+ Info
Mant-GTPγS
CAS :
- 136749-24-1
Mant-GTPγS, an effective GTP analog, displays strong competitive inhibition of adenylyl cyclase (AC). Additionally, it acts as a potent inhibitor of YdeH.
Formule :C₁₈H₂₃N₆O₁₄P₃S
Couleur et forme :Solid
Masse moléculaire :672.39
Ref: TM-T38782
+ Info
Lesogaberan napadisylate
CAS :
- 477956-38-0
Lesogaberan (AZD-3355) is a selective GABAB agonist with EC50 of 8.6 nM, Ki of 5.1 nM in rats, and acts peripherally on the esophageal sphincter.
Formule :C₁₃H₁₇FNO₅PS
Couleur et forme :Solid
Masse moléculaire :349.31
Ref: TM-T40572
+ Info
β-Amyloid (35-42)
CAS :
- 183292-41-3
β-Amyloid (35-42) is a peptide derived from the beta-amyloid protein, encompassing amino acids 35 through 42.
Formule :C₃₃H₆₀N₈O₉S
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :744.94
Ref: TM-TP1586
+ Info
GSK-3β inhibitor 27
GSK-3β inhibitor27 (Compound 1c) is a reversible, competitive inhibitor of GSK-3β with an IC50 value of 2.2 μM. It inhibits tau hyperphosphorylation and reduces Aβ protein aggregation, demonstrating metal chelation and neuroprotective potential. GSK-3β inhibitor27 is promising for research into neurodegenerative diseases, such as Alzheimer's disease.
Formule :C₁₆H₁₇ClN₄O₂
Couleur et forme :Solid
Masse moléculaire :332.79
Ref: TM-T207246
+ Info
HTR2A antagonist 1
HTR2A antagonist 1 (Compound 15f) is an HTR2A antagonist with an IC50 of 42.79 nM. It induces sub-G1 cell cycle arrest and apoptosis in colorectal cancer cells by activating the p53/p21/caspase 3 signaling pathway. HTR2A antagonist 1 exhibits good liver microsomal stability and is useful for colorectal cancer research.
Formule :C₃₅H₄₃Cl₂F₂N₅O₄
Couleur et forme :Solid
Masse moléculaire :706.65
Ref: TM-T204966
+ Info
β-Amyloid (1-9)
CAS :
- 147529-30-4
This is an N-terminal fragment of beta amyloid.
Formule :C₄₂H₆₀N₁₄O₁₇
Degré de pureté :98%
Couleur et forme :Solid
Masse moléculaire :1033.01
Ref: TM-TP1645
+ Info
AChE/BChE-IN-15
AChE/BChE-IN-15 (Compound 6d) serves as an inhibitor for both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), presenting inhibition constants (
Formule :C₂₉H₃₀N₆O₃
Couleur et forme :Solid
Masse moléculaire :510.59
Ref: TM-T78828
+ Info
AChE-IN-45
AChE-IN-45 (Compound 14) is an acetylcholinesterase (AChE) inhibitor exhibiting an IC50 value of 11.57±0.45 nM, and it demonstrates both antioxidant and
Couleur et forme :Odour Solid
Ref: TM-T83183
+ Info
AChE/MAO-B-IN-7
AChE/MAO-B-IN-7 (VAV-8) is a compound that acts as a dual inhibitor of acetylcholinesterase (AChE) and MAO-B, with the ability to cross the blood-brain barrier. It also inhibits the aggregation of Aβ42, making it a valuable compound for Alzheimer's disease (AD) research.
Formule :C₂₂H₂₁N₃O₃
Couleur et forme :Solid
Masse moléculaire :375.42
Ref: TM-T204841
+ Info
AChE-IN-29
AChE-IN-29, a 3-OH pyrrolidine derivative, acts as a cholinesterase (ChE) inhibitor with potent activity against human acetylcholinesterase (hAChE), electric
Formule :C₁₈H₁₉BrN₂O₂
Couleur et forme :Solid
Masse moléculaire :375.26
Ref: TM-T78905
+ Info
SSAO inhibitor-1
CAS :
- 2242883-04-9
SSAO Inhibitor-1 blocks SSAO, has anti-inflammatory effects, used in liver disease research.
Formule :C₁₇H₂₄FN₅O₂
Couleur et forme :Solid
Masse moléculaire :349.41
Ref: TM-T39741
+ Info
BChE-IN-40
BChE-IN-40 (compound D40) is a potent butyrylcholinesterase inhibitor with an IC50 of 0.59 μM. It demonstrates significant anti-inflammatory effects, with an IC50 of 4.55 μM in inhibiting nitric oxide production. Additionally, BChE-IN-40 exhibits excellent permeability across the blood-brain barrier.
Formule :C₂₈H₃₀N₂O₇
Couleur et forme :Solid
Masse moléculaire :506.2053
Ref: TM-T207209
+ Info
(Rac)-5-Hydroxymethyl Tolterodine hydrochloride
CAS :
- 250214-40-5
(Rac)-5-Hydroxymethyl Tolterodine HCl, or (Rac)-Desfesoterodine HCl, is a potent mAChR blocker researched for overactive bladder.
Formule :C₂₂H₃₂ClNO₂
Couleur et forme :Solid
Masse moléculaire :377.95
Ref: TM-T40161
+ Info
5-HT1AR/5-HT6R ligand-1
5-HT1AR/5-HT6R ligand-1 (Compound PP13) functions as a ligand for the 5-HT receptor, demonstrating high affinity for 5-HT1AR, 5-HT6R, and 5-HT7R with Ki values of 19, 69, and 198 nM, respectively. In HEK293 cells, it inhibits cAMP production with EC50 values of 1535, 488, and 53 nM for these receptors. Additionally, 5-HT1AR/5-HT6R ligand-1 exhibits antiproliferative effects on several cancer cell lines, including 1321N1, U87MG, MCF7, and AsPC-1, with IC50 values of 9.6, 13.6, 19.3, and 14.6 μM, respectively. The compound also shows antagonistic activity towards the dopamine receptor D2R, with a Ki of 1903 nM.
Formule :C₂₅H₂₉ClN₄O₂S
Couleur et forme :Solid
Masse moléculaire :485.04
Ref: TM-T205634
+ Info
CUR-IPA
CUR-IPA is a cholinesterase inhibitor with IC50 values of 5.99 μM for eAChE (electric eel), 59.30 μM for hAChE (human), and 60.66 μM for hBChE (human). It has free radical scavenging and antioxidant activity and is useful for researching cognitive dysfunction.
Formule :C₄₃H₃₈N₂O₈
Couleur et forme :Solid
Masse moléculaire :710.77
Ref: TM-T205484
+ Info
Lanuginosine
CAS :
- 23740-25-2
Lanuginosine, an aporphine alkaloid, exhibits cytotoxicity against U251.
Formule :C₁₈H₁₁NO₄
Couleur et forme :Solid
Masse moléculaire :305.28
Ref: TM-T32567
+ Info
SB656104
CAS :
- 446020-51-5
SB656104 is a bioactive chemical.
Formule :C₂₅H₃₀ClN₃O₃S
Couleur et forme :Solid
Masse moléculaire :488.04
Ref: TM-T34546
+ Info
Inaperisone
CAS :
- 99323-21-4
Inaperisone: a novel muscle relaxant that indirectly inhibits voiding reflex via brainstem GABAB receptors.
Formule :C₁₆H₂₃NO
Degré de pureté :99.48%
Couleur et forme :Solid
Masse moléculaire :245.36
Ref: TM-T68087
+ Info
nAChR modulator-1
CAS :
- 1902218-84-1
nAChR modulator-1, a insecticide, is a insect nAChR orthosteric modulator [1] .
Formule :C₁₂H₈ClN₃O₂
Couleur et forme :Solid
Masse moléculaire :261.66
Ref: TM-T74396
+ Info
Blestrin D
CAS :
- 145701-19-5
Blestrin D: BChE mixed-type inhibitor, IC50=8.1μM, from Bletilla striata, for AD research.
Formule :C₃₀H₂₄O₆
Couleur et forme :Solid
Masse moléculaire :480.51
Ref: TM-T75514