Neuroscience
Les inhibiteurs en neurosciences sont des composés conçus pour moduler l'activité de protéines, d'enzymes ou de récepteurs spécifiques au sein du système nerveux. Ces inhibiteurs sont cruciaux pour étudier les mécanismes moléculaires sous-jacents au fonctionnement neuronal, à la transmission synaptique et aux maladies neurodégénératives. En ciblant les récepteurs des neurotransmetteurs, les canaux ioniques et les voies de signalisation, les inhibiteurs en neurosciences facilitent l'exploration du fonctionnement cérébral et le développement de stratégies thérapeutiques pour des troubles neurologiques tels que la maladie d'Alzheimer, de Parkinson et l'épilepsie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs en neurosciences de haute qualité pour soutenir vos recherches en neurobiologie, neuropharmacologie et sciences cognitives.
Sous-catégories appartenant à la catégorie "Neuroscience"
- récepteur 5-HT(940 produits)
- ACK(1 produits)
- AChR(574 produits)
- ATP Citrate Lyase(16 produits)
- Récepteur adrénergique(2.939 produits)
- BACE(36 produits)
- Bêta-amyloïde(204 produits)
- CaMK(68 produits)
- COX(562 produits)
- Récepteur de la dopamine(407 produits)
- Récepteur GABA(336 produits)
- Gamma-sécrétase(59 produits)
- GluR(255 produits)
- GlyT(24 produits)
- Récepteur de l'histamine(358 produits)
- LRRK2(33 produits)
- Récepteur de la mélatonine(24 produits)
- NMDAR(28 produits)
- Récepteur OX(40 produits)
- Récepteur opioïde(296 produits)
Affichez 12 plus de sous-catégories
5400 produits trouvés pour "Neuroscience"
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L-689560
CAS :<p>L-689560, a radiolabeled ligand, studies NMDA receptors, is an antagonist at GluN1 glycine site.</p>Formule :C17H15Cl2N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :380.23PF-03382792
CAS :<p>PF-03382792 is a small molecule 5-HT4 receptor activator for the study of Alzheimer's disease.</p>Formule :C23H32FN3O4Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :433.52β-Amyloid (22-40)
CAS :<p>This synthetic peptide consists of amino acids 22 to 40 of beta amyloid protein.</p>Formule :C78H135N21O26SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1815.1AMI-193
CAS :<p>AMI-193 (Spiramide) is a selective 5-HT2 & D2 receptor antagonist with antipsychotic properties.</p>Formule :C22H26FN3O2Degré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :383.465-MeO-pyr-T
CAS :<p>5-MeO-pyr-T (5-Methoxy pyrrolidinyltryptamine) acts as a 5-HT1AR agonist, exhibiting Ki values of 0.577 μM and 373 μM for 5-HT1AR and 5-HT2AR, respectively. It inhibits the reuptake of 5-HT and triggers its release. Additionally, 5-MeO-pyr-T can induce reduced motor activity.</p>Formule :C15H20N2OCouleur et forme :SolidMasse moléculaire :244.33Doxacurium Chloride
CAS :<p>Doxacurium Chloride is a muscarinic acetylcholine receptor M2 antagonist.</p>Formule :C56H78ClN2O16Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1070.69Lesogaberan napadisylate
CAS :<p>Lesogaberan (AZD-3355) is a selective GABAB agonist with EC50 of 8.6 nM, Ki of 5.1 nM in rats, and acts peripherally on the esophageal sphincter.</p>Formule :C13H17FNO5PSCouleur et forme :SolidMasse moléculaire :349.31BuChE-IN-8
<p>BuChE-IN-8 (compound 19c), a butyrylcholinesterase (BuChE) inhibitor, exhibits an IC50 value of 559 nM and concurrently inhibits human β-secretase (BACE1) and</p>Formule :C28H33ClN4O2SCouleur et forme :SolidMasse moléculaire :525.11Moxonidine hydrochloride
CAS :<p>Moxonidine Hydrochloride: selective I1 imidazoline receptor agonist, stronger than α2-AR; lowers blood pressure; central action.</p>Formule :C9H13Cl2N5OCouleur et forme :SolidMasse moléculaire :278.14Eletriptan
CAS :<p>Eletriptan, second-generation triptans used to treat migraines, is used as an abortion drug.</p>Formule :C22H26N2O2SCouleur et forme :SolidMasse moléculaire :382.52Sulamserod
CAS :<p>Sulamserod (RS 100302) is a potent 5-HT4 receptor antagonist with antiarrhythmic activity for the study of atrial fibrillation and cardiovascular related</p>Formule :C19H28ClN3O5SDegré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :445.96ALEPH hydrochloride
CAS :<p>ALEPH (hydrochloride) acts as a partial agonist of h5-HT2A and h5-HT2B receptors, with EC50 values of 10.3 nM and 19.2 nM, respectively. It can induce head twitch responses in mice, with an ED50 of 0.80 mg/kg.</p>Formule :C12H20ClNO2SCouleur et forme :SolidMasse moléculaire :277.81Aceclidine (hydrochloride)
CAS :<p>agonist of muscarinic receptors</p>Formule :C9H16ClNO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :205.68Donitriptan hydrochloride
CAS :<p>Donitriptan hydrochloride (Donitriptan monohydrochloride) is a potent, high efficacy agonist of 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectively</p>Formule :C23H26ClN5O2Degré de pureté :99.8% - 99.86%Couleur et forme :SolidMasse moléculaire :439.944-Hydroxy MET
CAS :<p>4-Hydroxy MET (4-HO-MET) is a tryptamine-based new psychoactive substance (NPS), structurally similar to the endogenous neurotransmitter serotonin. It has hallucinogenic properties that affect mood, movement, and cognitive functions.</p>Formule :C13H18N2OCouleur et forme :SolidMasse moléculaire :218.3GABAA receptor modulator-3
<p>GABAA receptor modulator-3 (compound 3b) is a positive allosteric modulator (PAM). It inhibits the peak current and steady-state current of α1β3γ2 GABAAR with IC50 values of 671 μM and 64 μM, respectively.</p>Formule :C18H22O2Couleur et forme :SolidMasse moléculaire :270.37CGP 35348
CAS :<p>CGP 35348 是 GABAB 受体的选择性拮抗剂 (EC50 = 34 μM)。 CGP 35348 可用于研究白化新生小鼠脑损伤后的神经肌肉协调和空间学习。</p>Formule :C8H20NO4PDegré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :225.22β-Amyloid (35-42)
CAS :<p>β-Amyloid (35-42) is a peptide derived from the beta-amyloid protein, encompassing amino acids 35 through 42.</p>Formule :C33H60N8O9SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :744.94CHF-5022
CAS :<p>CHF-5022 is a nonsteroidal anti-inflammatory drug that selectively inhibits the production of beta-amyloid protein (1-42) (ABETA42).</p>Formule :C17H12F4O2Couleur et forme :SolidMasse moléculaire :324.27Brexpiprazole S-oxide D8
CAS :<p>Brexpiprazole S-oxide D8 (DM-3411 D8) is a deuterium-labeled metabolite of Brexpiprazole, a partial agonist at 5-HT1A and dopamine receptors.</p>Formule :C25H19D8N3O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :457.61Neocarzinostatin
CAS :<p>Neocarzinostatin is an effective DNA-damaging, anti-tumor antibiotic.</p>Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :N/ASSAO inhibitor-1
CAS :<p>SSAO Inhibitor-1 blocks SSAO, has anti-inflammatory effects, used in liver disease research.</p>Formule :C17H24FN5O2Couleur et forme :SolidMasse moléculaire :349.41YS-370
CAS :<p>YS-370 orally blocks P-gp, moderately inhibits CYP3A4, reverses drug resistance, and enhances paclitaxel's anticancer effects.</p>Formule :C37H35BrN4O3Degré de pureté :98.055%Couleur et forme :SolidMasse moléculaire :663.6Velnacrine
CAS :<p>Velnacrine (1,2,3,4-tetrahydro-9-aminoacridin-1-ol maleate) is a biochemical.</p>Formule :C13H14N2ODegré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :214.26N-Ethyl-N-(3-pyridylmethyl)amine
CAS :<p>N-Ethyl-N-(3-pyridylmethyl)amine has affinity for nAChR (Ki = 0.97 µM) and can be used in related research in the field of life sciences.</p>Formule :C8H12N2Degré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :136.19I2-IRs ligand-1
<p>I2-IRs ligand-1 (Compound 12d) is an orally active compound capable of crossing the blood-brain barrier. It exhibits high affinity for imidazoline I2 receptors (I2-IRs) with a pKi of 9.98. This compound can enhance cognitive deficits in aging mice and possesses analgesic, anti-inflammatory, and neuroprotective properties. I2-IRs ligand-1 is applicable for research in Alzheimer's disease and related pain disorders.</p>Formule :C21H23ClFN2O4PCouleur et forme :SolidMasse moléculaire :452.84Mant-GTPγS
CAS :<p>Mant-GTPγS, an effective GTP analog, displays strong competitive inhibition of adenylyl cyclase (AC). Additionally, it acts as a potent inhibitor of YdeH.</p>Formule :C18H23N6O14P3SCouleur et forme :SolidMasse moléculaire :672.39Rasagiline 13C3 mesylate racemic
CAS :<p>Rasagiline 13C3 mesylate racemic is the deuterium labeled Rasagiline, which is an irreversible monoamine oxidase inhibitor.</p>Formule :C13H17NO3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :270.32CDD0102 HCl
CAS :<p>CDD0102 HCl is a selective and potent M1 muscarinic receptor agonist for the treatment of Alzheimer's disease.</p>Formule :C8H13ClN4ODegré de pureté :99.7%Couleur et forme :SoildMasse moléculaire :216.67Nardoguaianone J
CAS :<p>Nardoguaianone J, a guaiane-type compound isolated from the roots of Nardostachys chinensis, has been shown to enhance SERT activity [1][2].</p>Formule :C15H22O2Couleur et forme :SolidMasse moléculaire :234.33HDAC6-IN-49
<p>HDAC6-IN-49 (Compound 3) is an inhibitor of HDAC, with IC50 values of 0.012 and 0.735 µM against HDAC6 and HDAC1, respectively. Additionally, it inhibits MAO-B, cholinesterase (ChE), histamine receptor (H3R), and serotonin 6 receptor (5-HT6R). HDAC6-IN-49 exhibits neuroprotective effects in SH-SY5Y cells and enhances cognitive functions and motor abilities in fruit fly models of Parkinson's disease and C. elegans models of Alzheimer's disease.</p>Couleur et forme :Odour SolidP-gb-IN-1
CAS :<p>P-gb-IN-1 is a potent P-glycoprotein (P-gp) inhibitor that exhibits reverse activity by inhibiting P-gp outflow.</p>Formule :C30H28N2O6Degré de pureté :99.58%Couleur et forme :SoildMasse moléculaire :512.55Flupyradifurone
CAS :<p>Flupyradifurone (flupyradifurone) is a systemic insecticide and nicotinic acetylcholine receptor (nAChR) agonist interfer nervous system of insects.</p>Formule :C12H11ClF2N2O2Degré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :288.68Epiboxidine
CAS :<p>Epiboxidine: Potent, selective nAChR agonist; Ki 0.46/1.2 nM for rat/human α4β2; analogous to Epibatidine and ABT 418.</p>Formule :C10H14N2OCouleur et forme :SolidMasse moléculaire :178.23Galanin (1-15) (porcine, rat)
CAS :<p>N-terminal galanin fragment used to mediate central cardiovascular effects</p>Formule :C72H105N19O20Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1556.72Blestrin D
CAS :<p>Blestrin D: BChE mixed-type inhibitor, IC50=8.1μM, from Bletilla striata, for AD research.</p>Formule :C30H24O6Couleur et forme :SolidMasse moléculaire :480.51Bensultap
CAS :<p>Bensultap is an agricultural chemical typically used as a pesticide.</p>Formule :C17H21NO4S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :431.61RAGE antagonist peptide
CAS :<p>RAGE antagonist blocks S100P/A4, HMGB-1; hinders glioma growth, metastasis; reduces PDAC cell growth, NF-κB activity; counters TDI effects in mice.</p>Formule :C57H101N13O17SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1272.56Jatrorrhizine hydroxide
CAS :<p>Jatrorrhizine hydroxide: alkaloid from Coptis chinensis; neuroprotective, antimicrobial, antiplasmodial, antioxidant; AChE inhibitor, affects 5-HT/NE uptake.</p>Formule :C20H21NO5Couleur et forme :SolidMasse moléculaire :355.38Crenezumab
CAS :<p>Crenezumab (MABT 5102A) is a fully humanized anti-amyloid-beta antibody that binds to multiple forms of amyloid-beta (Aβ) for the study of Alzheimer's disease.</p>Degré de pureté :97.5% (SDS-PAGE); 95.3% (SEC-HPLC) - 97.5% (SDS-PAGE); 95.3% (SEC-HPLC)Couleur et forme :LiquidCOX-2-IN-49
<p>COX-2-IN-49 (compound 6c) is a potent inhibitor of cyclooxygenase-2 (COX-2), displaying an IC50 value of 2.671 µM. This compound exhibits anti-proliferative properties and holds potential for use in cancer research.</p>Couleur et forme :Odour SolidAzocarnil
<p>Azocarnil is a GABAergic agonist-enhancer used in neurological system research.</p>Couleur et forme :Odour SolidAntidepressant agent 5
CAS :<p>Antidepressant agent 5 is a 7-substituted tetrahydroisoquinoline derivative with antidepressant activity.Antidepressant agent 5 acts similarly to magnoflorine</p>Formule :C20H25NO3Degré de pureté :99.34%Couleur et forme :SoildMasse moléculaire :327.422'-O-Succinyl-cAMP
CAS :<p>2'-O-Monosuccinyladenosine-3',5'-cyclic monophosphate is an immunogenic derivative of cAMP that has been used to generate anti-cAMP antisera and antibodies.1,2</p>Formule :C14H16N5O9PCouleur et forme :SolidMasse moléculaire :429.282Proadrenomedullin (1-20), human
CAS :<p>Endogenous peptide; agonist of MRGPRX2 (EC50=251 nM); noncompetitive inhibitor of nicotinic receptors; reduces catecholamine secretion; antihypertensive.</p>Formule :C112H178N36O27Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2460.84Mirtazapine N-oxide
CAS :<p>Mirtazapine N-oxide, a mirtazapine metabolite, is produced by CYP1A2 and CYP3A4 in human liver.</p>Formule :C17H19N3OCouleur et forme :SolidMasse moléculaire :281.359LY 293284
CAS :<p>LY 293284 is a potent, selective full agonist of 5-HT1A receptor with anxiogenic effects in animal studies.</p>Formule :C19H26N2OCouleur et forme :SolidMasse moléculaire :298.42Desmethyl Mirtazapine (hydrochloride)
CAS :<p>Desmethyl mirtazapine is a metabolite of the antidepressant mirtazapine.1It is formed from mirtazapine by the cytochrome P450 (CYP) isoform CYP3A4.</p>Formule :C16H18ClN3Couleur et forme :SolidMasse moléculaire :287.79Pyrantel hydrochloride
CAS :<p>Pyrantel hydrochloride is the hydrochloride form of Pyrantel. Pyrantel is is an anthelmintic and a nicotinic acetylcholine receptor (nAChR) agonist.</p>Formule :C11H15ClN2SDegré de pureté :98.01%Couleur et forme :SoildMasse moléculaire :242.773-Hydroxy desalkylflurazepam
CAS :<p>3-Hydroxy desalkylflurazepam is a benzodiazepine compound with potential sedative and anxiolytic effects.</p>Formule :C15H10ClFN2O2Couleur et forme :SolidMasse moléculaire :304.77-Methyl DMT
CAS :<p>7-Methyl DMT (7-TMT) acts as a 5-HT2 receptor agonist. Structurally, it is a tryptamine derivative and serves as an analytical reference for the psychoactive substance DOM. It is also applicable in research related to neurological disorders.</p>Formule :C13H18N2Couleur et forme :SolidMasse moléculaire :202.3Rilmazolam
CAS :<p>Rilmazolam is a triazolobenzodiazepine compound and serves as the active metabolite of Rilmazafone.</p>Formule :C19H15Cl2N5OCouleur et forme :SolidMasse moléculaire :400.26Fipronil sulfone
CAS :<p>Fipronil sulfone is an insecticide fipronil. Its metabolite fipronil sulphone is an inhibitor of rat ɑ1β2γ2L GABA(A) receptor.</p>Formule :C12H4Cl2F6N4O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :453.14Melatonin-Tamoxifen Conjugate
<p>Melatonin-Tamoxifen Conjugate (compound 16c) is an anticancer drug conjugate made of Melatonin and Tamoxifen, serving as an effective antagonist of ERα (IC50 = 863 nM). In cells expressing the hMT1 receptor, it binds to MLT receptors (Ki = 3.1 nM) and exhibits the ability to promote β-arrestin activation (EC50 = 914 nM) and ERK activation (EC50 = 98 nM). The IC50 values for Melatonin-Tamoxifen Conjugate in MCF-7, MDA-MB-231, and HT-1080 cell lines are 6.8 μM, 6.4 μM, and 1.7 μM, respectively.</p>Formule :C47H58N4O4Couleur et forme :SolidMasse moléculaire :742.99NPS ALX Compound 4a hydrochloride(1:1)
<p>NPS ALX Compound 4a hydrochloride(1:1) is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist, with an IC50 of 7.2 nM and a Ki of 0.2 nM.</p>Formule :C25H26ClN3O2SDegré de pureté :99.84%Couleur et forme :SoildMasse moléculaire :468.014-hydroxy DiPT hydrochloride
CAS :<p>4-hydroxy DiPT (hydrochloride) is a 5-HT2A agonist that can induce head twitch response (HTR) in mice, indicating its hallucinogenic potential. This compound holds promise for research into hallucinogens.</p>Formule :C16H25ClN2OCouleur et forme :SolidMasse moléculaire :296.84AChE/BChE-IN-25
<p>AChE/BChE-IN-25 (Compound 6e) is an orally active inhibitor of hAChE and eqBChE, with IC50 values of 7.9 nM and 0.79 nM, respectively. This compound exhibits antioxidant activity, effective in scavenging free radicals with an IC50 of 22.91 μM. AChE/BChE-IN-25 demonstrates neuroprotective effects by reducing mitochondrial and cellular oxidative stress in a Drosophila Alzheimer's model and improves spatial and cognitive memory impairments induced by Scopolamine in mouse models.</p>Formule :C21H24ClN3O2Couleur et forme :SolidMasse moléculaire :385.89MIDD0301
CAS :<p>MIDD0301 is a potent positive allosteric α5β3γ selective GABAA receptor (GABAAR) ligand with EC50 of 17 nM.</p>Formule :C19H13BrFN3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :414.23Fabesetron
CAS :<p>Fabesetron (FK1052): oral dual antagonist for 5-HT3/5-HT4 receptors. Aids in managing acute and delayed chemo-induced emesis.</p>Formule :C18H19N3OCouleur et forme :SolidMasse moléculaire :293.37Lanuginosine
CAS :<p>Lanuginosine, an aporphine alkaloid, exhibits cytotoxicity against U251.</p>Formule :C18H11NO4Couleur et forme :SolidMasse moléculaire :305.28TC-2559 difumarate
CAS :<p>TC-2559 difumarate: Oral α4β2 nAChR partial agonist, CNS-selective, EC50 0.18 μM, prefers α4β2 over α2β4/α4β4/α3β4, antinociceptive.</p>Formule :C20H26N2O9Couleur et forme :SolidMasse moléculaire :438.43BChE-IN-39
<p>BChE-IN-39 (Compound 7c) selectively inhibits butyrylcholinesterase (BChE) with an IC50 of 0.08 μM, while showing an IC50 of 3.98 μM for acetylcholinesterase (AChE) inhibition. Additionally, BChE-IN-39 downregulates GSK-3β expression, thereby inhibiting the excessive phosphorylation of tau protein.</p>Formule :C29H23ClFN3O3Couleur et forme :SolidMasse moléculaire :515.963TRV-7019
CAS :<p>TRV-7019: BBB-permeable radioligand for brain imaging, used in diagnosing amyloid diseases, MS, and brain tumors.</p>Formule :C14H12INO3Couleur et forme :SolidMasse moléculaire :369.15(Iso)-Samixogrel
CAS :<p>(Iso)-Samixogrel shows activity against Carbonic anhydrase and Cyclooxygenase 2.</p>Formule :C25H25ClN2O4SDegré de pureté :98.80%Couleur et forme :SolidMasse moléculaire :484.99Orexin A (human, rat, mouse) (TFA)
<p>Endogenous orexin receptor agonist with Ki of 20 nM (OX1) and 38 nM (OX2), promotes feeding, may regulate sleep-wake cycle.</p>Formule :C154H244N47F3O46S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3675.12Emamectin B1a
CAS :<p>Emamectin B1a can be used in relevant research in the life sciences. Its product number is T37663 and CAS number is 121124-29-6.</p>Formule :C49H75NO13Couleur et forme :SolidMasse moléculaire :886.133Arisugacin G
CAS :<p>Arisugacin G, a microbial metabolite, is a structural analogue of Arisugacin A. Unlike its analogue, Arisugacin G does not exhibit activity against AChE (acetylcholinesterase).</p>Formule :C27H32O5Couleur et forme :SolidMasse moléculaire :436.54L-AP3
CAS :<p>L-AP3 blocks mGluR, inhibits D/L-phosphoserine (IC50: 368/2087 μM).</p>Formule :C3H8NO5PCouleur et forme :White Hygroscopic SolidMasse moléculaire :169.073Maesopsin
<p>Maesopsin is a useful organic compound for research related to life sciences and the catalog number is T124581.</p>Formule :C15H12O6Couleur et forme :SolidMasse moléculaire :288.2555-MeO-MET
CAS :<p>5-MeO-MET (5-Methoxy-N-methyl-N-ethyltryptamine) is a compound belonging to the 5-methoxytryptamine class. It acts as an agonist for 5-HT1A and 5-HT2A receptors. In mice, 5-MeO-MET inhibits locomotion and has sedative effects.</p>Formule :C14H20N2OCouleur et forme :SolidMasse moléculaire :232.32γ-Secretase modulator 10
CAS :<p>γ-Secretase modulator 10 is a novel γ-secretase modulator.</p>Formule :C25H23F3N4O2Couleur et forme :SolidMasse moléculaire :468.48GSK-3β inhibitor 27
<p>GSK-3β inhibitor27 (Compound 1c) is a reversible, competitive inhibitor of GSK-3β with an IC50 value of 2.2 μM. It inhibits tau hyperphosphorylation and reduces Aβ protein aggregation, demonstrating metal chelation and neuroprotective potential. GSK-3β inhibitor27 is promising for research into neurodegenerative diseases, such as Alzheimer's disease.</p>Formule :C16H17ClN4O2Couleur et forme :SolidMasse moléculaire :332.79LRRK2 inhibitor 1
CAS :<p>LRRK2 inhibitor 1 is a selective and potent LRRK2 inhibitor with an IC50 of 13 nM.LRRK2 inhibitor 1 inhibits DCLK1 kinase with an IC50 value of 2.61 nM.</p>Formule :C20H23N5O4Degré de pureté :99.94%Couleur et forme :SolidMasse moléculaire :397.43(+)-Cinchonaminone
CAS :<p>(+)-Cinchonaminone shows monoamine oxidase (MAO) inhibitory activity.</p>Formule :C19H24N2O2Couleur et forme :SolidMasse moléculaire :312.413(S)-3,4-DCPG HCl
<p>(S)-3,4-DCPG HCl is a selective mGluR8a agonist, impacting AV12-664 cells with an EC50 of 31 nM.</p>Formule :C10H10ClNO6Degré de pureté :99.53% - 99.9%Couleur et forme :SoildMasse moléculaire :275.64C18 L-erythro Ceramide (d18:1/18:0)
CAS :<p>C18 L-erythro Ceramide, a natural stereoisomer, inhibits rat brain mt-CDase with IC50 of 8.8 μM.</p>Formule :C36H71NO3Couleur et forme :SolidMasse moléculaire :565.95rac-Desethyl Oxybutynin (hydrochloride)
CAS :<p>rac-Desethyl oxybutynin, active oxybutynin metabolite, binds to mAChRs; K_i values 3.12-16 nM; lowers rat micturition pressure.</p>Formule :C20H28ClNO3Couleur et forme :SolidMasse moléculaire :365.895-Hydroxymethyl tolterodine formate
CAS :<p>5-Hydroxymethyl tolterodine (formate) (PNU-200577 (formic)) is an active metabolite of the muscarinic acetylcholine receptor antagonists Tolterodine and Fesoterodine. It is synthesized by the cytochrome P450 (CYP) isoenzyme CYP2D6 and plasma esterases.</p>Formule :C23H33NO4Couleur et forme :SolidMasse moléculaire :387.51LEK 8804
CAS :<p>LEK 8804 is a 5-HT(2) receptor antagonist and 5-HT(1A) receptor agonist.</p>Formule :C19H19N3OCouleur et forme :SolidMasse moléculaire :305.37RuBi-Nicotine
CAS :<p>Nicotinic receptor agonist</p>Formule :C40H44Cl2N8RuDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :808.815-AAM-2-CP
CAS :<p>5-AAM-2-CP is one of the major metabolites of Acetamiprid. Acetamiprid, a nAChR agonist, is a neonicotinoid insecticide used worldwide.</p>Formule :C8H9ClN2ODegré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :184.62α-Bungarotoxin
CAS :<p>Neurotoxin that blocks neuromuscular transmission via irreversible inhibition of nicotinic ACh receptors (nAChRs).</p>Formule :C338H529N97O105S11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :7984.14NT 13 acetate
<p>NT 13 acetate is a partial agonist of NMDA receptor and can be used for research on depression, anxiety, and other related diseases.</p>Formule :C20H34N4O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :474.51Otaplimastat HCl
CAS :<p>Otaplimastat HCl is an MMP inhibitor reducing NMDA-mediated excitotoxicity and oxidative stress, restoring TIMP levels, and protecting vascular permeability.</p>Formule :C28H35ClN6O5Degré de pureté :100%Masse moléculaire :571.07nAChR agonist CMPI hydrochloride
CAS :<p>CMPI hydrochloride: Potent α4:α4 nAChR PAM; EC50 0.26 μM for (α4)3(β2)2 response to ACh; may aid nicotine dependence, neuropsychiatric research.</p>Formule :C18H20Cl2N4OCouleur et forme :SolidMasse moléculaire :379.29β-Amyloid (1-28)
CAS :<p>β-Amyloid (1-28) is a β-Amyloid protein fragment involved in metal binding.</p>Formule :C145H209N41O46Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3262.51sabcomeline
CAS :<p>Sabcomeline: potent, selective M1 agonist; boosts cognition; for Alzheimer's study.</p>Formule :C10H15N3OCouleur et forme :SolidMasse moléculaire :193.25Perlapine
CAS :<p>Perlapine is an effective and selective HM3DQ DREADD agonist (EC50 = 2.8 nM).</p>Formule :C19H21N3Couleur et forme :SolidMasse moléculaire :291.391,8-Cineole
CAS :<p>Eucalyptol, a natural monoterpenoid and cyclic ether found in eucalyptus species, effectively controls excessive airway mucus secretion and asthma by inhibiting pro-inflammatory cytokines. It serves as an efficacious treatment for non-purulent sinusitis, reducing inflammation and pain when applied topically, and demonstrating leukemic cell-killing capabilities in vitro.</p>Formule :C10H18ODegré de pureté :97.44% - 97.44%Couleur et forme :SolidMasse moléculaire :154.25mGluR5 modulator 1
CAS :<p>mGluR5 modulator 1 is a positive modulator for mGluR5, used in schizophrenia and cognitive research.</p>Formule :C18H19ClFN3O2Couleur et forme :SolidMasse moléculaire :363.82AC 253
CAS :<p>Amylin (AMY3) receptor antagonist; blocks cAMP, Ca2+, PKA, MAPK, Akt, and cFOS activity; prevents Aβ-induced neuronal death. Cyclic AC 253 variant exists.</p>Formule :C122H196N40O39Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2847.11γ-Secretase Modulators
CAS :<p>gamma-Secretase Modulators serves as a useful treatment for Alzheimer's disease by inhibiting the production of Amyloid-β.</p>Formule :C26H24F3N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :483.4825N-NBOMe hydrochloride
CAS :<p>25N-NBOMe hydrochloride is a derivative of 2C-N and acts as an agonist for the 5-HT2A and 5-HT2C receptors, with Ki values of 0.144 nM and 1.06 nM, respectively. It has minimal effect on the release of preloaded neurotransmitters from recombinant dopamine, serotonin, and norepinephrine transporters.</p>Formule :C18H23ClN2O5Couleur et forme :SolidMasse moléculaire :382.84SB 699551
CAS :<p>SB 699551 is a selective 5-HT5A antagonist (Ki=6.31 nM) that enhances 5-HT neuronal function. It inhibits SERT (Ki=25.12 nM),inhibit breast cancer.</p>Formule :C34H45N3ODegré de pureté :99.83%Masse moléculaire :511.74Tiquizium
CAS :<p>Tiquizium has effective Antimuscarinic effect, and causes significant bronchodilation in patients with chronic obstructive pulmonary disease.</p>Formule :C19H24NS2Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :330.53CZC-54252 hydrochloride
CAS :<p>CZC-54252 hydrochloride: selective LRRK2 inhibitor; IC50 = 1.85/1.28 nM (wild-type/G2019S); neuroprotective; EC50 = 1 nM for G2019S injury.</p>Formule :C22H26Cl2N6O4SDegré de pureté :98.21%Couleur et forme :SolidMasse moléculaire :541.45Calmodulin-Dependent Protein Kinase II (281-309)
CAS :<p>Calmodulin-Dependent Protein Kinase II (281-309) is a synthetic peptide that can be phosphorylated at Thr286 by PKC and inhibits CaM kinase II (IC50 = 80 nM).</p>Formule :C146H254N46O39S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3374.06β-Amyloid (10-20)
CAS :<p>Amyloid β-Protein (10-20) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Amyloid β protein fragment containing the α-</p>Formule :C71H99N17O16Degré de pureté :98%Couleur et forme :Lyophilized PowderMasse moléculaire :1446.65BChE-IN-21
<p>BChE-IN-21, a potent inhibitor of butyrylcholinesterase (BChE), exhibits an inhibition constant (IC50) of 0.14 ± 0.02 μM, indicating promise for research in</p>Couleur et forme :Odour SolidSoclenicant
CAS :<p>Soclenicant is a negative-altering modulator of α 7 -nAChR for anxiety, depression, and PTSD, due to its high selectivity, oral availability</p>Formule :C24H26N4O3Degré de pureté :99.57%Couleur et forme :SoildMasse moléculaire :418.49Desalkylgidazepam
CAS :<p>Desalkylgidazepam, a benzodiazepine compound, is a metabolite of gidazepam. It is capable of activating both GABA A-type receptors and the translocator protein (TSPO).</p>Formule :C15H11BrN2OCouleur et forme :SolidMasse moléculaire :315.17Emraclidine
CAS :<p>Emraclidine (CVL-231) is a novel, highly selective allosteric modulator of the muscarinic M4 receptor positive receptor.Cost-effective and quality-assured.</p>Formule :C20H21F3N4ODegré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :390.4Amyloid β-Protein (1-24)
CAS :<p>Amyloid β-Protein (1-24) is a peptide identified through peptide screening. This tool predominantly employs immunoassays to gather and analyze active peptides. Peptide screening is utilized in studies involving protein interactions, functional analysis, and epitope screening, particularly relevant in the research and development of active molecules.</p>Formule :C130H183N35O40Masse moléculaire :2876.05JNJ-67569762
CAS :<p>JNJ-67569762 is a selective BACE1 inhibitor targeting the S3 pocket ( IC 50 = 2.7 nM).</p>Formule :C22H22F4N4O5SCouleur et forme :SolidMasse moléculaire :530.494-Bromo-2,5-DMMA
CAS :<p>4-Bromo-2,5-DMMA (Compound 2) demonstrates affinity for the 5-HT2 binding site and has an ED50 of 0.82 mg/kg in rat discrimination experiments.</p>Formule :C12H18BrNO2Couleur et forme :SolidMasse moléculaire :288.18bPiDDB
CAS :<p>bPiDDB (N,N'-Dodecylbis-Picolinium Bromide) is a nicotinic receptor (nAChR) antagonist.</p>Formule :C24H38Br2N2Degré de pureté :98.72%Couleur et forme :SolidMasse moléculaire :514.38MR33317
<p>MR33317 is an inhibitor of acetylcholinesterase with an IC50 value of 41 nM. Additionally, it acts as an agonist for brain 5-HT4 receptors.</p>Formule :C22H28ClN3O2Masse moléculaire :401.187Cytidine 5′-diphosphoethanolamine
CAS :<p>Cytidine 5′-diphosphoethanolamine, a key intermediate in phosphatidylethanolamine synthesis, also serves as a stimulant of Ach synthesis [1].</p>Formule :C11H20N4O11P2Couleur et forme :SolidMasse moléculaire :446.24FITC-β-Ala-Amyloid β-Protein (1-42)
CAS :<p>FITC-β-Ala-Amyloid β-Protein (1-42) is a polypeptide identified through peptide screening. This screening method predominantly utilizes immunoassays to gather active polypeptides and is used in studying protein interactions, conducting functional analyses, and screening antigen epitopes, with particular application in the research and development of active molecules.</p>Formule :C227H327N57O66S2Masse moléculaire :4971.34251Anisatin
<p>Anisatin is a useful organic compound for research related to life sciences and the catalog number is T124719.</p>Formule :C15H20O8Couleur et forme :SolidMasse moléculaire :328.317CPN-351
CAS :<p>CPN-351 (compound 9a) is a pentapeptide that acts as a selective antagonist for human NMUR1, with a pA2 value of 7.35. It exhibits ten times greater antagonistic activity toward human NMUR1 compared to NMUR2. CPN-351 is applicable in inflammation research.</p>Formule :C45H61N13O6SMasse moléculaire :912.116,7-dimethylisatin
CAS :<p>6,7-Dimethylisatin (6,7-dimethyl-1H-indole-2,3-dione) inhibits hGAT3 with IC50 of 108 μM. 6,7-Dimethylisatin also inhibits hBGT1, hGAT2.</p>Formule :C10H9NO2Degré de pureté :98.98%Couleur et forme :SolidMasse moléculaire :175.18DOPR hydrochloride
CAS :<p>DOPR hydrochloride is a psychoactive substance belonging to the amphetamine class.</p>Formule :C14H24ClNO2Couleur et forme :SolidMasse moléculaire :273.8Cinazepam
CAS :<p>Cinazepam is a GABAA receptor partial agonist and a benzodiazepine derivative with anxiolytic and sedative properties. Cinazepam can be utilized in research related to sleep disorders.</p>Formule :C19H14BrClN2O5Couleur et forme :SolidMasse moléculaire :465.68p-Xylene bis(pyridinium bromide)
CAS :<p>p-Xylene bis(pyridinium bromide) (compound 21) is a cationic quenching agent and acts as a weak bis-quaternary ammonium salt inhibitor for AChE and BChE, with IC50 values of 1540 μM and 529 μM, respectively.</p>Formule :C18H18Br2N2Couleur et forme :SolidMasse moléculaire :422.16TET-13
<p>TET-13 is a positive allosteric modulator of the GABAA receptor with an EC50 of 5.65 μM, which is more potent than Etomidate (EC50: 9.29 μM). It exhibits strong anesthetic effects in both mice and rats, with an ED50 of 0.48 mg/kg in mice and 0.69 mg/kg in rats.</p>Formule :C15H16N2O3SCouleur et forme :SolidMasse moléculaire :304.36Arotinolol hydrochloride
CAS :<p>Arotinolol HCl is a non-selective α/β-blocker, anti-hypertensive, anti-obesity, and improves aortic stiffness.</p>Formule :C15H22ClN3O2S3Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :408AChE-IN-49
<p>AChE-IN-49 (Compd (S)-7g) is an acetylcholinesterase (AChE) inhibitor with an IC50 value of 0.0003 μM.</p>Formule :C31H28BrClN2O3Masse moléculaire :590.09718SB 216641
CAS :<p>SB 216641 is a 5-HT (1B/1D) antagonist with anxiolytic activity for the study of anxiety disorders and depression.</p>Formule :C28H30N4O4Degré de pureté :98.09%Couleur et forme :SolidMasse moléculaire :486.56COX-2-IN-35
<p>COX-2-IN-35 (compound 7) is a selective inhibitor of COX-2, demonstrating anti-inflammatory activity, with an inhibitory concentration (IC 50) of 4.37 nM [1].</p>Formule :C22H19NO2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :393.52Lu AE51090
CAS :<p>Lu AE51090 is a selective muscarinic M1 receptor agonist with minimal off-target effects, receptor function and selective pharmacological modulation.</p>Formule :C24H29N3O3Degré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :407.51GluN2B receptor modulator-1
CAS :<p>GluN2B receptor modulator-1 is a selective negative allosteric modulator of NMDA receptor GluN2B subunits (IC50 31 nM), valuable for neuropharmacology studies.</p>Formule :C17H15F3N4O2SDegré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :396.39ECPLA
CAS :<p>ECPLA is an LSD analog and a potent 5-HT2A agonist (EC50 of 14.6 nM), capable of stimulating Gq-mediated calcium flux. It exhibits high affinity for most serotonin receptors, α2-adrenergic receptors, and D2-like dopamine receptors.</p>Formule :C21H25N3OCouleur et forme :SolidMasse moléculaire :335.44Tranylcypromine
CAS :<p>Tranylcypromine (SKF 385), a potent monoamine oxidase (MAO) inhibitor [1], is used in medicinal applications.</p>Formule :C9H11NDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :133.19hAChE-IN-6
<p>hAChE-IN-6 (compound 51) is a brain-penetrant acetylcholinesterase (AChE) inhibitor exhibiting an IC50 of 0.16 μM.</p>Couleur et forme :Odour SolidJPC0323
<p>JPC0323 is a dual positive allosteric modulator of the 5-HT2C and 5-HT2A receptors, featuring on-target properties, acceptable plasma exposure, and adequate</p>Formule :C22H43NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :385.58Syk Inhibitor II hydrochloride
CAS :<p>Syk signaling is key in lupus. Syk inhibitors reduce inflammation and sepsis severity in FcgRIIb-/- mice, lowering cytokines and organ damage.</p>Formule :C14H16ClF3N6ODegré de pureté :99.05%Couleur et forme :SolidMasse moléculaire :376.77Pomaglumetad methionil anhydrous
CAS :<p>LY2140023, potential schizophrenia treatment, is an oral prodrug of LY404039, a selective mGlu2/3 agonist.</p>Formule :C12H18N2O7S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :366.41Anti-inflammatory agent 53
<p>Anti-inflammatory agent 52 (compound 7c) is an orally active, selective COX-2 inhibitor with demonstrated anti-HT29 metastatic activity, causing periodic arrest</p>Formule :C24H22N2O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :434.51hAChE-IN-3
<p>hAChE-IN-3 (compound 5c) serves as a potent inhibitor for AChE, BuChE, MAO-B, and BACE-1, with respective IC50 values of 0.44, 0.08, 5.15, and 0.38 μM,</p>Formule :C30H24ClN3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :541.98Alosetron
CAS :<p>Alosetron, a 5-HT3 antagonist, is used for the management of severe diarrhea-predominant irritable bowel syndrome (IBS) in women only.</p>Formule :C17H18N4ODegré de pureté :98%Couleur et forme :Crystalline PowderMasse moléculaire :294.36Furosemide sodium
CAS :<p>Furosemide sodium: potent NKCC inhibitor, loop diuretic, treats heart failure, hypertension, edema, selective GABAA antagonist.</p>Formule :C12H10ClN2NaO5SDegré de pureté :99.52% - >99.99%Couleur et forme :SolidMasse moléculaire :352.73Serazapine
CAS :<p>Serazapine is a highly specific serotonin (5-HT2) binding inhibitor with anxiolytic activity for the treatment of anxiety disorders.</p>Formule :C22H23N3O2Degré de pureté :98.71% - 99.57%Couleur et forme :SolidMasse moléculaire :361.44Flufiprole
CAS :<p>Flufiprole is used as a phenylpyrazole pesticide. It has enantioselective metabolism in human and rat liver microsomes.</p>Formule :C16H10Cl2F6N4OSCouleur et forme :SolidMasse moléculaire :491.24BSB
CAS :<p>BSB is a Congo red-derived fluorescent probe, an amyloid protein imaging agent, interacting with amyloid fibrils formed by Aβ (1-40) peptides in rodents.</p>Formule :C24H17BrO6Degré de pureté :95.53%Couleur et forme :SolidMasse moléculaire :481.29MAO-B-IN-24
<p>MAO-B-IN-24 (compound 11h) is a selective, reversible, competitive inhibitor of MAO-B with an IC50 value of 1.60 μM.</p>Formule :C20H18N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :302.37COX-2-IN-31
<p>COX-2-IN-31 (compound 7b) is an orally active dual inhibitor targeting COX-2 (IC50=60 nM) and 5-LOX (IC50=1.9 μM).</p>Formule :C17H16N6O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :400.41Anti-inflammatory agent 52
<p>Anti-inflammatory agent 52 (compound 7j) is an orally active, selective COX-2 inhibitor with the capability to induce G2/M phase arrest and exhibit anti-HT29</p>Formule :C24H21ClN2O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :452.95Calmodulin Kinase IINtide, Myristoylated
<p>Myristoylated Calmodulin Kinase IINtide (Myr-CaMKIINtide) serves as a selective and noncompetitive inhibitor of CaMKII [1].</p>Formule :C156H275N47O43Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3497.14Anabaseine
CAS :<p>Anabaseine is a broad nicotinic agonist, favoring alpha-7 AChRs in muscle/brain, and weakly stimulates alpha-4 beta-2 nAChRs.</p>Formule :C10H12N2Couleur et forme :SolidMasse moléculaire :160.22AChE-IN-42
<p>Compound AChE-IN-42, also known as Compound 28, is an acetylcholinesterase (AChE) inhibitor with an inhibition constant (K i) of 0.44 μM [1].</p>Couleur et forme :Odour SolidAHN-683
CAS :<p>AHN-683 is a fluorescent ligand. It was used for peripheral-type benzodiazepine receptors.</p>Formule :C42H32FN3O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :709.72LP 12 hydrochloride
CAS :<p>LP 12 hydrochloride is a selective 5-HT7 receptor agonist (Ki=0.13 nM).</p>Formule :C32H40ClN3OCouleur et forme :SolidMasse moléculaire :518.14α-Conotoxin PIA TFA
<p>α-Conotoxin PIA TFA, targeting nicotinic acetylcholine receptor (nAChR) subtypes with α6 and α3 subunits, acts as an antagonist.</p>Formule :C81H126F3N27O27S4Degré de pureté :98.81%Couleur et forme :SolidMasse moléculaire :2095.3C175-0062
CAS :<p>C175-0062, a monoamine oxidase B (MAO-B) inhibitor, is applicable in research focused on neurodegenerative disorders such as Parkinson's disease (PD), Alzheimer's disease (AD), and amyotrophic lateral sclerosis (ALS) [1].</p>Formule :C21H18N2O5Couleur et forme :SolidMasse moléculaire :378.38NMDA receptor antagonist 7
<p>Compound (S)-10a, a GluN2B subunit-selective NMDA receptor antagonist, exhibits a K i of 93 nM and an IC 50 of 72 nM.</p>Formule :C22H27N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :349.47Lysyl hydroxylase 2-IN-1
<p>"Lysyl Hydroxylase 2-IN-1 (compound 12) is a selective inhibitor of lysyl hydroxylase 2 (LH2) with an IC50 of approximately 300 nM and demonstrates specificity</p>Formule :C18H18N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :310.35MAO-B-IN-4
<p>MAO-B-IN-4 (Compound 26) is a reversible monoamine oxidase B (MAO-B) inhibitor with potent in vitro activity, characterized by an IC50 value of 9 nM.</p>Formule :C23H20ClF2N3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :411.87PF-06827443
<p>PF-06827443 is a orally bioavailable, CNS-penetrant M1-selective PAM with minimal agonist activity.</p>Formule :C24H24N2O4Couleur et forme :SolidMasse moléculaire :404.47CaMKIIα-PHOTAC
<p>CaMKIIα-PHOTAC is a photochemically targeted chimera (PHOTAC) that specifically targets Ca2+/calmodulin-dependent protein kinase II α (CaMKIIα).</p>Formule :C54H58Cl2N10O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1094MmTx1 toxin
<p>Micrurotoxin 1 (MmTx1 toxin) acts as an allosteric modulator of GABA A receptors, enhancing the receptor's sensitivity to its agonist [1].</p>Formule :C295H455N95O97S10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :7205β-Amyloid (4-10)
CAS :<p>Antibodies corresponding to beta-amyloid (4-10) are effective in vivo inhibitors of cytotoxicity, amyloid plaque formation and special memory disturbances in</p>Formule :C39H52N12O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :880.9Oxatomide
CAS :<p>Oxatomide: Dual H1/P2X7 antagonist, antihistamine, anti-allergic, treats immune diseases, IC50: 0.95 μM (P2X7), 0.43 μM (5-HT).</p>Formule :C27H30N4ODegré de pureté :98.82% - 99.72%Couleur et forme :White PowderMasse moléculaire :426.55Guvacine hydrobromide
CAS :<p>Guvacine hydrobromide, an alkaloid derived from the Areca catechu nut, serves as a potent inhibitor of GABA (GABA uptakp) uptake.</p>Formule :C6H10BrNO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :208.05LY836
<p>LY836 is an orally active, neuroprotective compound that effectively inhibits the PSD95-nNOS association in cortical neurons.</p>Degré de pureté :98%Couleur et forme :Odour Solid5-HT6R antagonist 1
<p>Compound 8 (5-HT6R antagonist 1), a 5-HT6R antagonist (K i : 5 nM), not only demonstrates inhibition of platelet aggregation and excellent metabolic stability</p>Formule :C17H22F2N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :364.39β-Amyloid (1-40)
CAS :<p>Amyloid β1-40 is one of the fragments generated after cleavage of the amyloid peptide precursor protein by β and γ secretases.</p>Formule :C194H295N53O58SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :4329.82Dehydrodiscretamine chloride
CAS :<p>Dehydrodiscretamine chloride, a dual inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), exhibits IC50 values of 17.8 μM and 118.8 μM,</p>Formule :C19H18ClNO4Couleur et forme :SolidMasse moléculaire :359.8PD07
<p>PD07 is an orally active acetylcholinesterase (AChE) inhibitor, exhibiting an IC50 of 0.29 μM against human AChE, and demonstrates inhibition of cholinesterases</p>Formule :C23H21ClN2O4Couleur et forme :SolidMasse moléculaire :424.88trans-Cevimeline hydrochloride
CAS :<p>AF 102A hydrochloride is a biochemical.</p>Formule :C10H18ClNOSCouleur et forme :SolidMasse moléculaire :235.77(Rac)-Norcisapride
CAS :<p>Norcisapride, a 5-HT3 and 5-HT4 agonist, treats GI, orofacial, and ENT disorders.</p>Formule :C14H20ClN3O3Degré de pureté :99.32%Couleur et forme :SoildMasse moléculaire :313.78BMS-906024
CAS :<p>BMS-906024 (Osugacestat) is a gamma secretase inhibitor, a Notch inhibitor.BMS-906024 has broad-spectrum antitumour activity.</p>Formule :C26H26F6N4O3Degré de pureté :99.88% - >99.99%Couleur et forme :SolidMasse moléculaire :556.5Ethylpropyltryptamine
CAS :<p>Ethylpropyltryptamine (EPT) is an orally active novel psychoactive substance. It is predicted to act as a partial agonist of the 5-HT2A receptor.</p>Formule :C15H22N2Couleur et forme :SolidMasse moléculaire :230.358-Aminoadenine
CAS :<p>8-Aminoadenine (7H-purine-6,8-diamine) is a ligand for Adenine Receptor with Ki of 0.0341 μM.</p>Formule :C5H6N6Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :150.14(Rac)-Sabcomeline
CAS :<p>(Rac)-Sabcomeline ((Rac)-SB-202026) is an M1/M4 muscarinic agonist used in the study of neurologic disorders such as schizophrenia.</p>Formule :C10H15N3ODegré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :193.25Cianopramine hydrochloride
CAS :<p>Cianopramine hydrochloride is a bio-active chemical.</p>Formule :C20H24ClN3Couleur et forme :SolidMasse moléculaire :341.88(E/Z)-Sivopixant
CAS :<p>(E/Z)-Sivopixant ((E/Z)-S-600918)is a potent P2X3 receptor antagonist, IC50 = 4 nM. (E/Z)-Sivopixant can be used for respiratory diseases research.</p>Formule :C25H22ClN5O5Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :507.93TAT-CN21 (scrambled)
<p>TAT-CN21(scrambled) is a control peptide lacking specific targeting activity and serves as a negative control for TatCN21. TatCN21 is an effective and selective inhibitory peptide for calcium/calmodulin-dependent protein kinase II (CaMKII).</p>Couleur et forme :Odour SolidTAT-CN21
<p>TatCN21, with an IC 50 of 77 nM, serves as a potent and selective inhibitor peptide of the calcium/calmodulin-dependent protein kinase II (CaMKII), a ubiquitously-expressed multifunctional serine/threonine protein kinase. It is particularly useful in research pertaining to ischemia and neurodegenerative diseases.</p>Formule :C169H303N69O43Couleur et forme :SolidMasse moléculaire :3989.65LBG20304
<p>LBG20304 (compound 2s) serves as a ligand for the homologous GluK5 receptor, demonstrating an IC50 of 432 nM and exhibiting over 40-fold selectivity against the GluK1-3 isoforms. At concentrations below 10 μM, LBG20304 shows neither agonistic nor antagonistic effects on heterologous GluK2/5 receptors. However, at concentrations above 10 μM, it displays minimal agonist activity in neuronal slices (rat).</p>Formule :C19H18N4O5Couleur et forme :SolidMasse moléculaire :382.37COX-1/2-IN-9
<p>COX-1/2-IN-9 (Compound 3n) serves as a selective and potent inhibitor of both COX-1 and COX-2, demonstrating IC 50 values of 0.031 µM for COX-1 and 0.01 µM for COX-2. This compound exhibits antibacterial and anti-inflammatory properties, effectively targeting MRSA 1478 (MIC=50 μg/mL) and multidrug-resistant S. lentus (MIC=50 μg/mL). Furthermore, COX-1/2-IN-9 shows promise in relieving MRSA-induced pneumonia in conditions of compromised immunity.</p>Formule :C30H20IN9O13S2Couleur et forme :SolidMasse moléculaire :905.57(S)-Vamicamide
CAS :<p>(S)-Vamicamide is an anti-anticholinergic compound.</p>Formule :C18H23N3ODegré de pureté :99.48% - 99.65%Couleur et forme :SoildMasse moléculaire :297.39AC1-IN-1
CAS :<p>AC1-IN-1 is a selective inhibitor of adenylyl cyclase type 1 (AC1, IC50 = 0.54 µM).</p>Formule :C18H18FN5O2Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :355.37(S,S)-BMS-984923
CAS :<p>(S,S)-BMS-984923 is a weak mGluR5 modulator with EC50 >1μM; less active than its potent counterpart.</p>Formule :C22H15ClN2O2Couleur et forme :SolidMasse moléculaire :374.82BMY-14802
CAS :<p>BMY-14802 (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) is a selective and orally active sigma-1 antagonist with an IC50 of 112 nM.</p>Formule :C18H22F2N4ODegré de pureté :99.84%Couleur et forme :SoildMasse moléculaire :348.39RS 56812
CAS :<p>RS 56812 is a 5-HT3 receptor antagonist and agonist used in the study of cognitive disorders.</p>Formule :C18H21N3O2Degré de pureté :99.38%Couleur et forme :SoildMasse moléculaire :311.38Bencycloquidium Bromide
CAS :<p>Bencycloquidium bromide is an M3 muscarinic antagonist that reduces nasal secretion in allergic rhinitis and has high affinity for M3 receptors.</p>Formule :C21H32BrNO2Couleur et forme :SolidMasse moléculaire :410.39AChE-IN-27
CAS :<p>AChE-IN-27 is a small molecule used for high-throughput assays.</p>Formule :C20H14N2O3Degré de pureté :98.54%Couleur et forme :SolidMasse moléculaire :330.34Pemedolac
CAS :<p>Pemedolac (Dexpemedolac) is a small molecule COX inhibitor used to treat neurological disorders, skin and musculoskeletal disorders.</p>Formule :C22H23NO3Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :349.42BTMPS
CAS :<p>BTMPS is a usage-dependent nicotinic antagonist capable of reducing acute withdrawal symptoms associated with morphine use.</p>Formule :C28H52N2O4Degré de pureté :98.1%Couleur et forme :SolidMasse moléculaire :480.72(S)-3,4-DCPG
CAS :<p>(S)-3,4-DCPG ((S)-3,4-Dicarboxyphenylglycine) is a selective agonist of human metabotropic glutamate receptor 8a (mGluR8a).</p>Formule :C10H9NO6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :239.181H-Indole-3-carboxylic acid, 5-[2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]propoxy]-2-methyl-1-(4-methylphenyl)-, ethyl ester
CAS :<p>Compound 5936-0108对β-淀粉样蛋白可能具有调节作用。</p>Formule :C26H34N2O7Degré de pureté :99.44%Couleur et forme :SoildMasse moléculaire :486.56Trontinemab
CAS :<p>Trontinemab, a bispecific humanized IgG1-κ antibody, targets the amyloid beta A4 precursor protein (APP) and transferrin receptor p90, CD71 (TFRC).</p>Degré de pureté :96.77% - 99%Couleur et forme :LiquidNF023 hexasodium
CAS :<p>NF023 hexasodium is a selective and competitive P2X1 receptor antagonist, with IC50 values of 0.21 μM, 28.9 μM, > 50 μM and > 100 μM for human P2X1, P2X3, P2X2</p>Formule :C35H26N4Na6O21S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1168.92CP 465022
CAS :<p>CP 465022 hydrochloride is a potent AMPA receptor antagonist with anti-seizure properties, inhibiting responses at an IC50 of 25 nM.</p>Formule :C26H24ClFN4ODegré de pureté :99.05%Couleur et forme :SolidMasse moléculaire :462.95Calmodulin-Dependent Protein Kinase II 290-309 acetate
<p>Calmodulin-Dependent Protein Kinase II 290-309 acetate is an effective antagonist of Ca2+/calmodulin-dependent protein kinase II (IC50 = 52 nM).</p>Formule :C105H189N31O26SDegré de pureté :96.7%Couleur et forme :SolidMasse moléculaire :2333.88Camlipixant
CAS :<p>Camlipixant (BLU-5937) is an orally active purine P2X3 receptor antagonist that is potent, selective and competitive.</p>Formule :C23H24F2N4O4Degré de pureté :99.37%Couleur et forme :SoildMasse moléculaire :458.46Fasciculic acid C
CAS :<p>Fasciculic acid C is a calmodulin antagonist isolated from mushroom Naematoloma fasciculare.</p>Formule :C38H63NO11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :709.91(R)-Citalopram oxalate
CAS :<p>(R)-Citalopram oxalate is a weak selective serotonin reuptake inhibitor (SSRI) that antagonises its S-isomer (escitalopram), anticonvulsant and antidepressant</p>Formule :C22H23FN2O5Degré de pureté :99.76%Couleur et forme :White SolidMasse moléculaire :414.43Nitrazolam
CAS :<p>Nitrazolam is a benzodiazepine compound that may exhibit central nervous system depressant properties similar to traditional benzodiazepine drugs by acting on the GABA receptors (GABA receptor). These effects include sedation, hypnosis, anxiolytic, and anticonvulsant activities.</p>Formule :C17H13N5O2Couleur et forme :SolidMasse moléculaire :319.32β-Amyloid (13-27)
CAS :<p>β-Amyloid (13-27) is a peptide consisting of amino acid of 13 to 27 of beta amyloid protein.</p>Formule :C84H126N24O24Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1856.05Paynantheine
CAS :<p>Paynantheine is an alkaloid with antinociceptive properties, found in Mitragyna speciosa. It also acts as an agonist at 5-HT1AR and 5-HT2BR receptors, inducing lower lip contraction and providing antinociception in rats.</p>Formule :C23H28N2O4Couleur et forme :SolidMasse moléculaire :396.48MAO-B-IN-38
<p>MAO-B-IN-38 (Compound 6b) is a reversible, competitive inhibitor of MAO-B, exhibiting IC50 values of 0.03 µM for MAO-B and 21.46 µM for MAO-A. This compound is applicable in research on neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease.</p>Formule :C14H17FN4O2S3Couleur et forme :SolidMasse moléculaire :388.504β-Amyloid (29-40)
CAS :<p>β-Amyloid (29-40) is a fragment of Amyloid-β peptide.Alzheimer's beta amyloid peptide (29-40/42) C-terminal fragments have physical and chemical properties</p>Formule :C49H88N12O13SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1085.36mGluR3 modulator-1
CAS :<p>1-ethyl-3-morpholin-4-yl tetrahydroisoquinoline: mGluR3 modulator, potential for Parkinson's.</p>Formule :C16H21N3ODegré de pureté :98.99%Couleur et forme :SolidMasse moléculaire :271.36KRP-199 sodium
<p>KRP-199 sodium sodium is highly potent and selective for AMPA-R in vitro and exhibits good neuroprotection in vivo.</p>Formule :C22H12F3N5Na2O7Degré de pureté :97.27%Couleur et forme :SoildMasse moléculaire :561.33CALP2 TFA
<p>CALP2 TFA, a CaM antagonist with 7.9 µM Kd, blocks CaM-dependent enzymes, boosts Ca2+ levels, and activates macrophages.</p>Formule :C70H105F3N14O15SCouleur et forme :SolidMasse moléculaire :1471.72Furosemide
CAS :<p>Furosemide is a potent NKCC2 (Na-K-2Cl symporter) inhibitor, used for edema and chronic renal insufficiency.</p>Formule :C12H11ClN2O5SDegré de pureté :99.32% - 99.89%Couleur et forme :Crystals From Aqueous Ethanol Tasteless (Ntp 1992)Masse moléculaire :330.744(D-Asp1)-Amyloid β-Protein (1-42)
CAS :<p>(D-Asp1)-Amyloid β-Protein (1-42), a peptide fragment of amyloid β-protein (Aβ), serves as the primary constituent of vascular and parenchymal amyloid deposits</p>Formule :C203H311N55O60SCouleur et forme :SolidMasse moléculaire :4514.04Asenapine citrate
CAS :<p>Asenapine citrate: atypical antipsychotic for schizophrenia, bipolar disorder; targets serotonin, adrenoceptors, dopamine, histamine (pKi: 8.2-10.5).</p>Formule :C23H24ClNO8Couleur et forme :SolidMasse moléculaire :477.89
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