Neuroscience
Les inhibiteurs en neurosciences sont des composés conçus pour moduler l'activité de protéines, d'enzymes ou de récepteurs spécifiques au sein du système nerveux. Ces inhibiteurs sont cruciaux pour étudier les mécanismes moléculaires sous-jacents au fonctionnement neuronal, à la transmission synaptique et aux maladies neurodégénératives. En ciblant les récepteurs des neurotransmetteurs, les canaux ioniques et les voies de signalisation, les inhibiteurs en neurosciences facilitent l'exploration du fonctionnement cérébral et le développement de stratégies thérapeutiques pour des troubles neurologiques tels que la maladie d'Alzheimer, de Parkinson et l'épilepsie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs en neurosciences de haute qualité pour soutenir vos recherches en neurobiologie, neuropharmacologie et sciences cognitives.
Sous-catégories appartenant à la catégorie "Neuroscience"
- récepteur 5-HT(940 produits)
- ACK(1 produits)
- AChR(574 produits)
- ATP Citrate Lyase(16 produits)
- Récepteur adrénergique(2.939 produits)
- BACE(36 produits)
- Bêta-amyloïde(204 produits)
- CaMK(68 produits)
- COX(562 produits)
- Récepteur de la dopamine(407 produits)
- Récepteur GABA(336 produits)
- Gamma-sécrétase(59 produits)
- GluR(255 produits)
- GlyT(24 produits)
- Récepteur de l'histamine(358 produits)
- LRRK2(33 produits)
- Récepteur de la mélatonine(24 produits)
- NMDAR(28 produits)
- Récepteur OX(40 produits)
- Récepteur opioïde(296 produits)
Affichez 12 plus de sous-catégories
5400 produits trouvés pour "Neuroscience"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
β-Amyloid (18-28)
CAS :<p>Intracerebroventricular administration of synthetic peptides Beta-amyloid (12-20), (12-28), and (18-28) causes amnesia in mice.</p>Formule :C55H81N13O18Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1212.31Cevimeline hydrochloride hemihydrate
CAS :<p>Cevimeline hydrochloride hemihydrate is a novel muscarinic receptor agonist, used as a candidate therapeutic drug for xerostomia in Sjogren's syndrome.</p>Formule :C20H38Cl2N2O3S2Degré de pureté :97.00%Couleur et forme :SolidMasse moléculaire :489.55TAT-CN21
<p>TatCN21, with an IC 50 of 77 nM, serves as a potent and selective inhibitor peptide of the calcium/calmodulin-dependent protein kinase II (CaMKII), a ubiquitously-expressed multifunctional serine/threonine protein kinase. It is particularly useful in research pertaining to ischemia and neurodegenerative diseases.</p>Formule :C169H303N69O43Couleur et forme :SolidMasse moléculaire :3989.65Dual AChE-MAO B-IN-3
<p>Compound C10 is a potent dual AChE/MAO-B inhibitor with IC50s of 0.58μM (AChE) and 0.41μM (MAO-B), useful in Alzheimer's research.</p>Formule :C30H26F3NO3Couleur et forme :SolidMasse moléculaire :505.53Echimidine N-oxide
CAS :<p>Echimidine N-oxide, a pyrrolizidine alkaloid, exhibits significant inhibitory activity against acetylcholinesterase (AChE) with an IC50 value of 0.347 mM.</p>Formule :C20H31NO8Couleur et forme :SolidMasse moléculaire :413.467α-Conotoxin EI
CAS :<p>Selective antagonist of neuromuscular nicotinic receptors α1β1γδ</p>Formule :C83H125N27O27S5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2093.37COX-1-IN-2
<p>COX-1-IN-2 (compound 5h) serves as a potent anti-inflammatory and analgesic agent. This compound demonstrates a significant inhibitory effect on COX-1, with an IC 50 value of 38.76 nM.</p>Formule :C29H22FN3OSCouleur et forme :SolidMasse moléculaire :479.57AChE/BChE-IN-11
CAS :<p>AChE/BChE-IN-11, natural from artichoke leaves, inhibits AChE and BChE (IC50: 70/71 μM) for Alzheimer's research.</p>Formule :C21H22O12Couleur et forme :SolidMasse moléculaire :466.39Riluzole-13C,15N2
CAS :<p>Riluzole-13C,15N2 (PK 26124-13C,15N2) is a 13C and 15N labeled form of Riluzole, a glutamate antagonist with anticonvulsant activity, inhibiting GABA uptake.</p>Formule :CC7H5F3OS15N2Couleur et forme :SolidMasse moléculaire :237.18Dicloromezotiaz
CAS :<p>Dicloromezotiaz: Potent insecticide targeting nAChRs, controls various lepidoptera.</p>Formule :C19H12Cl3N3O2SCouleur et forme :SolidMasse moléculaire :452.74MGS0028
CAS :<p>MGS0028 is a selective agonist of metabotropic glutamate 2/3 receptor, it could reverse abnormal behaviors in mice induced by isolation rearing.</p>Formule :C8H8FNO5Couleur et forme :SolidMasse moléculaire :217.15β-Amyloid (11-22)
CAS :<p>β-Amyloid (11-22) is a peptide fragment of β-Amyloid.Beta-amyloid peptide (Abeta), the major constituent of amyloid plaques in the brains of Alzheimer’s</p>Formule :C70H102N18O18Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1483.67Multitarget AD inhibitor-1
CAS :<p>Multitarget AD inhibitor-1: reversible, selective BuChE blocker, inhibits β-secretase and amyloid/tau aggregation, promising for Alzheimer's research.</p>Formule :C29H38N2OCouleur et forme :SolidMasse moléculaire :430.636β-Amyloid (29-40)
CAS :<p>β-Amyloid (29-40) is a fragment of Amyloid-β peptide.Alzheimer's beta amyloid peptide (29-40/42) C-terminal fragments have physical and chemical properties</p>Formule :C49H88N12O13SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1085.36hAChE/hBuChE-IN-1
<p>hAChE/hBuChE-IN-1 (compound C2) acts as a dual inhibitor of cholinesterases, exhibiting IC50 values of 514 nM for hAChE and 358 nM for hBuChE. It is orally active and capable of enhancing cognitive function and spatial memory.</p>Formule :C30H31FN2O3Couleur et forme :SolidMasse moléculaire :486.577nAChR modulator-1
CAS :<p>nAChR modulator-1, a insecticide, is a insect nAChR orthosteric modulator [1] .</p>Formule :C12H8ClN3O2Couleur et forme :SolidMasse moléculaire :261.66AC1-IN-1
CAS :<p>AC1-IN-1 is a selective inhibitor of adenylyl cyclase type 1 (AC1, IC50 = 0.54 µM).</p>Formule :C18H18FN5O2Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :355.37BChE-IN-10
CAS :<p>BChE-IN-10, a strong mixed BChE inhibitor (IC50=6.4 μM), comes from Bletilla striata for AD research.</p>Formule :C23H20O5Couleur et forme :SolidMasse moléculaire :376.4γ-Secretase modulator 10
CAS :<p>γ-Secretase modulator 10 is a novel γ-secretase modulator.</p>Formule :C25H23F3N4O2Couleur et forme :SolidMasse moléculaire :468.48AChE/BuChE-IN-6
<p>AChE/BuChE-IN-6 (Compound 11f) is an inhibitor of AChE and BuChE, with IC50 values of 1.24 and 1.85 μg/mL, respectively. It exhibits strong DPPH radical scavenging activity (IC50 = 3.15 μg/mL). In vivo toxicity studies demonstrate that AChE/BuChE-IN-6 is safe, showing no significant differences in blood and biochemical parameters compared to controls, and no abnormalities in liver and kidney tissues. This compound shows potential for Alzheimer's disease research.</p>Formule :C24H20ClN3O3Couleur et forme :SolidMasse moléculaire :433.887MGS0274
CAS :<p>MGS0274, a lipophilic prodrug of mGlu2/3 agonist MGS0008, enhances oral bioavailability, potentially aiding schizophrenia research.</p>Formule :C21H32FNO7Couleur et forme :SolidMasse moléculaire :429.485HTR2A antagonist 1
<p>HTR2A antagonist 1 (Compound 15f) is an HTR2A antagonist with an IC50 of 42.79 nM. It induces sub-G1 cell cycle arrest and apoptosis in colorectal cancer cells by activating the p53/p21/caspase 3 signaling pathway. HTR2A antagonist 1 exhibits good liver microsomal stability and is useful for colorectal cancer research.</p>Formule :C35H43Cl2F2N5O4Couleur et forme :SolidMasse moléculaire :706.65Bencycloquidium Bromide
CAS :<p>Bencycloquidium bromide is an M3 muscarinic antagonist that reduces nasal secretion in allergic rhinitis and has high affinity for M3 receptors.</p>Formule :C21H32BrNO2Couleur et forme :SolidMasse moléculaire :410.39Navicixizumab
CAS :<p>Navicixizumab, a bispecific VEGF/DLL4 inhibitor, pairs with Paclitaxel in ovarian and other cancer research.</p>Couleur et forme :LiquidLycoramine hydrobromide
CAS :<p>Lycoramine is a natural alkaloid isolated from Lycoris chinensis.</p>Formule :C17H24BrNO3Couleur et forme :SolidMasse moléculaire :370.28AChE/MAO-B-IN-7
<p>AChE/MAO-B-IN-7 (VAV-8) is a compound that acts as a dual inhibitor of acetylcholinesterase (AChE) and MAO-B, with the ability to cross the blood-brain barrier. It also inhibits the aggregation of Aβ42, making it a valuable compound for Alzheimer's disease (AD) research.</p>Formule :C22H21N3O3Couleur et forme :SolidMasse moléculaire :375.42BChE-IN-19
<p>BChE-IN-19 (Compound 7b), a para-substituted indone derivative, exhibits potent inhibitory activity against butyryl cholinesterase (BChE) with an IC50 value of</p>Formule :C25H31NO5Couleur et forme :SolidMasse moléculaire :425.52Perlapine
CAS :<p>Perlapine is an effective and selective HM3DQ DREADD agonist (EC50 = 2.8 nM).</p>Formule :C19H21N3Couleur et forme :SolidMasse moléculaire :291.39TRV-7019
CAS :<p>TRV-7019: BBB-permeable radioligand for brain imaging, used in diagnosing amyloid diseases, MS, and brain tumors.</p>Formule :C14H12INO3Couleur et forme :SolidMasse moléculaire :369.15Antipsychotic agent-2
<p>Compound 11: potent antipsychotic, binds 5-HT1A/2A/2C, D2, H1 receptors; K is 56.6-1140 nM, BBB permeable.</p>Formule :C22H26FN5OCouleur et forme :SolidMasse moléculaire :395.47GABAA receptor modulator-3
<p>GABAA receptor modulator-3 (compound 3b) is a positive allosteric modulator (PAM). It inhibits the peak current and steady-state current of α1β3γ2 GABAAR with IC50 values of 671 μM and 64 μM, respectively.</p>Formule :C18H22O2Couleur et forme :SolidMasse moléculaire :270.37Millmerranone A
<p>Millmerranone A shows the acetylcholinesterase inhibitory property.</p>Formule :C27H28O9Couleur et forme :SolidMasse moléculaire :496.51Cinanserin hydrochloride
CAS :<p>Cinanserin hydrochloride (SQ 10643) is a 5-HT2 receptor blocker (Ki: 41 nM) and SARS-CoV 3C-like protease inhibitor.</p>Formule :C20H25ClN2OSDegré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :376.94Dehydrodiscretamine chloride
CAS :<p>Dehydrodiscretamine chloride, a dual inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), exhibits IC50 values of 17.8 μM and 118.8 μM,</p>Formule :C19H18ClNO4Couleur et forme :SolidMasse moléculaire :359.8(S)-3,4-DCPG
CAS :<p>(S)-3,4-DCPG ((S)-3,4-Dicarboxyphenylglycine) is a selective agonist of human metabotropic glutamate receptor 8a (mGluR8a).</p>Formule :C10H9NO6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :239.18(-)-Coclaurine hydrochloride
CAS :<p>(-)-Coclaurine hydrochloride is an antagonist of nAChRs isolated from Sarcopetalum harveyanum.</p>Formule :C17H20ClNO3Degré de pureté :99.07%Couleur et forme :SoildMasse moléculaire :321.8Cloxacepride
CAS :<p>cloxacepride is a CaM antagonist that is used to treat asthma disease.</p>Formule :C22H27Cl2N3O4Degré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :468.37SB 699551
CAS :<p>SB 699551 is a selective 5-HT5A antagonist (Ki=6.31 nM) that enhances 5-HT neuronal function. It inhibits SERT (Ki=25.12 nM),inhibit breast cancer.</p>Formule :C34H45N3ODegré de pureté :99.83%Masse moléculaire :511.74LP 12 hydrochloride
CAS :<p>LP 12 hydrochloride is a selective 5-HT7 receptor agonist (Ki=0.13 nM).</p>Formule :C32H40ClN3OCouleur et forme :SolidMasse moléculaire :518.14RuBi-GABA
CAS :<p>Ruthenium-bipyridine-triphenylphosphine caged GABA</p>Formule :C42H39F6N5O2P2RuDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :922.81H-Indole-3-carboxylic acid, 5-[2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]propoxy]-2-methyl-1-(4-methylphenyl)-, ethyl ester
CAS :<p>Compound 5936-0108对β-淀粉样蛋白可能具有调节作用。</p>Formule :C26H34N2O7Degré de pureté :99.44%Couleur et forme :SoildMasse moléculaire :486.56AHN-683
CAS :<p>AHN-683 is a fluorescent ligand. It was used for peripheral-type benzodiazepine receptors.</p>Formule :C42H32FN3O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :709.72Anabaseine
CAS :<p>Anabaseine is a broad nicotinic agonist, favoring alpha-7 AChRs in muscle/brain, and weakly stimulates alpha-4 beta-2 nAChRs.</p>Formule :C10H12N2Couleur et forme :SolidMasse moléculaire :160.224-Methoxyphenyl isothiocyanate
CAS :<p>4-Methoxyphenyl isothiocyanate (4-Methylphenyl ITC) is recognized as an antioxidant demonstrating an IC50 of 1.25 mM for scavenging DPPH free radicals. Its antioxidant capacity, as shown by the ORAC test, is 11.7 mM TE, equivalent to the efficacy of 11.7 mmol Trolox under similar conditions. Additionally, it extends the oxidation process in the Briggs–Rauscher reaction by approximately 9180 seconds. The compound also exhibits moderate cholinesterase inhibitory activity, with an inhibition rate of 30.4% for acetylcholinesterase (AChE) and 17.9% for butyrylcholinesterase (BChE). Research suggests 4-Methoxyphenyl isothiocyanate holds promise for applications in antioxidant and neurological disorder studies.</p>Formule :C8H7NOSCouleur et forme :SolidMasse moléculaire :165.21CALP2
CAS :<p>CALP2 is a CaM antagonist blocking EF-hand/Ca2+ site; inhibits CaM phosphodiesterase, raises Ca2+, and activates alveolar macrophages.</p>Formule :C68H104N14O13SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1357.72Aβ1-14-εK-KKK-MvF5 Th
<p>Aβ1-14-εK-KKK-MvF5 Th (UB311 immunogen I) is a biologically active peptide and one of the Aβ1–14 targeting peptides (B-cell epitope) used in UB-311.</p>Formule :C199H318N56O55Masse moléculaire :4372.38081Amyloid β-Protein (1-24)
CAS :<p>Amyloid β-Protein (1-24) is a peptide identified through peptide screening. This tool predominantly employs immunoassays to gather and analyze active peptides. Peptide screening is utilized in studies involving protein interactions, functional analysis, and epitope screening, particularly relevant in the research and development of active molecules.</p>Formule :C130H183N35O40Masse moléculaire :2876.05α-Conotoxin imi
CAS :<p>alpha-Conotoxin imi is a nicotinic acetylcholine receptor ligand.</p>Formule :C52H78N20O15S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1351.565-HT6R antagonist 1
<p>Compound 8 (5-HT6R antagonist 1), a 5-HT6R antagonist (K i : 5 nM), not only demonstrates inhibition of platelet aggregation and excellent metabolic stability</p>Formule :C17H22F2N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :364.39LY3027788
CAS :<p>LY3027788, potent oral prodrug of LY3020371, is a strong mGlu2/3 antagonist with notable antidepressant effects.</p>Formule :C25H31F2NO11SCouleur et forme :SolidMasse moléculaire :591.58
![1H-Indole-3-carboxylic acid, 5-[2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]propoxy]…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT67751.webp&w=3840&q=75)
