Neuroscience
Les inhibiteurs en neurosciences sont des composés conçus pour moduler l'activité de protéines, d'enzymes ou de récepteurs spécifiques au sein du système nerveux. Ces inhibiteurs sont cruciaux pour étudier les mécanismes moléculaires sous-jacents au fonctionnement neuronal, à la transmission synaptique et aux maladies neurodégénératives. En ciblant les récepteurs des neurotransmetteurs, les canaux ioniques et les voies de signalisation, les inhibiteurs en neurosciences facilitent l'exploration du fonctionnement cérébral et le développement de stratégies thérapeutiques pour des troubles neurologiques tels que la maladie d'Alzheimer, de Parkinson et l'épilepsie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs en neurosciences de haute qualité pour soutenir vos recherches en neurobiologie, neuropharmacologie et sciences cognitives.
Sous-catégories appartenant à la catégorie "Neuroscience"
- récepteur 5-HT(940 produits)
- ACK(1 produits)
- AChR(574 produits)
- ATP Citrate Lyase(16 produits)
- Récepteur adrénergique(2.939 produits)
- BACE(36 produits)
- Bêta-amyloïde(204 produits)
- CaMK(68 produits)
- COX(562 produits)
- Récepteur de la dopamine(407 produits)
- Récepteur GABA(336 produits)
- Gamma-sécrétase(59 produits)
- GluR(255 produits)
- GlyT(24 produits)
- Récepteur de l'histamine(358 produits)
- LRRK2(33 produits)
- Récepteur de la mélatonine(24 produits)
- NMDAR(28 produits)
- Récepteur OX(40 produits)
- Récepteur opioïde(296 produits)
Affichez 12 plus de sous-catégories
5400 produits trouvés pour "Neuroscience"
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α-Bungarotoxin
CAS :<p>Neurotoxin that blocks neuromuscular transmission via irreversible inhibition of nicotinic ACh receptors (nAChRs).</p>Formule :C338H529N97O105S11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :7984.14Cevimeline hydrochloride hemihydrate
CAS :<p>Cevimeline hydrochloride hemihydrate is a novel muscarinic receptor agonist, used as a candidate therapeutic drug for xerostomia in Sjogren's syndrome.</p>Formule :C20H38Cl2N2O3S2Degré de pureté :97.00%Couleur et forme :SolidMasse moléculaire :489.55AChE-IN-37
<p>AChE-IN-37 (compound A2) is an acetylcholinesterase inhibitor with an inhibitory concentration (IC50) of 0.23 µM.</p>Formule :C21H12ClNO7SCouleur et forme :SolidMasse moléculaire :457.84Syk Inhibitor II hydrochloride
CAS :<p>Syk signaling is key in lupus. Syk inhibitors reduce inflammation and sepsis severity in FcgRIIb-/- mice, lowering cytokines and organ damage.</p>Formule :C14H16ClF3N6ODegré de pureté :99.05%Couleur et forme :SolidMasse moléculaire :376.77LBG20304
<p>LBG20304 (compound 2s) serves as a ligand for the homologous GluK5 receptor, demonstrating an IC50 of 432 nM and exhibiting over 40-fold selectivity against the GluK1-3 isoforms. At concentrations below 10 μM, LBG20304 shows neither agonistic nor antagonistic effects on heterologous GluK2/5 receptors. However, at concentrations above 10 μM, it displays minimal agonist activity in neuronal slices (rat).</p>Formule :C19H18N4O5Couleur et forme :SolidMasse moléculaire :382.37LY3027788
CAS :<p>LY3027788, potent oral prodrug of LY3020371, is a strong mGlu2/3 antagonist with notable antidepressant effects.</p>Formule :C25H31F2NO11SCouleur et forme :SolidMasse moléculaire :591.58AChE-IN-70
<p>AChE-IN-70 (compound 4) is an acetylcholinesterase inhibitor. It exhibits larvicidal activity against mosquito larvae (Culex pipiens L.), making it useful for mosquito control research.</p>Couleur et forme :Odour SolidFasciculic acid A
CAS :<p>Fasciculic acid A is a calmodulin antagonist isolated from mushroom Naematoloma fasciculare.</p>Formule :C36H60O8Couleur et forme :SolidMasse moléculaire :620.868MAO-B-IN-20
<p>MAO-B-IN-20, potent with 0.037 μM IC50, is stable and BBB permeable, useful for Parkinson's research.</p>Formule :C20H18F2N2O2Couleur et forme :SolidMasse moléculaire :356.37G923-0271
CAS :<p>G923-0271 is a TDP-43 inhibitor that improves disease phenotypes in TDP-43 nematode models and reduces the overexpression of human TDP-43, ALS FTD.</p>Formule :C28H23FN4OCouleur et forme :SolidMasse moléculaire :450.51Imipramine N-oxide
CAS :<p>Imipramine N-oxide is a tricyclic antidepressant (TCA) and imipramine analogue used to treat depression.</p>Formule :C19H24N2ODegré de pureté :99.80%Couleur et forme :SolidMasse moléculaire :296.41COX-2-IN-34
CAS :<p>COX-2-IN-34 is a selective, orally potent COX-2 inhibitor that shows anti-inflammatory activity without gastric ulcer toxicity during experiments in mice.</p>Formule :C13H11NO4Degré de pureté :98.08%Couleur et forme :SoildMasse moléculaire :245.23DOAM
CAS :<p>DOAM is an antagonist of the 5-HT2 receptor.</p>Formule :C16H27NO2Couleur et forme :SolidMasse moléculaire :265.39hAChE-IN-5
<p>hAChE-IN-5 (compound 49) is a dual inhibitor of human acetylcholinesterase (hAChE) and human butyrylcholinesterase (hBuChE), exhibiting inhibitory potency with</p>Degré de pureté :98%Couleur et forme :Odour SolidSmall Cardioactive Peptide B (SCPB)
CAS :<p>SCPB: neurally active peptide, boosts adenylate cyclase in heart/gills, EC50s: 0.1 μM (heart), 1.0 μM (gills).</p>Formule :C52H80N14O11S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1141.41(D-Asp1)-Amyloid β-Protein (1-42)
CAS :<p>(D-Asp1)-Amyloid β-Protein (1-42), a peptide fragment of amyloid β-protein (Aβ), serves as the primary constituent of vascular and parenchymal amyloid deposits</p>Formule :C203H311N55O60SCouleur et forme :SolidMasse moléculaire :4514.045-HT2C agonist-4
CAS :<p>Compound 3i, a 5-HT2C agonist-4, acts as an agonist for the 5-HT2C receptor with an EC50 of 5.7 nM. It is capable of reducing locomotor activity in zebrafish larvae.</p>Formule :C24H25N5OCouleur et forme :SolidMasse moléculaire :399.49Emraclidine
CAS :<p>Emraclidine (CVL-231) is a novel, highly selective allosteric modulator of the muscarinic M4 receptor positive receptor.Cost-effective and quality-assured.</p>Formule :C20H21F3N4ODegré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :390.4BACE1-IN-15
<p>BACE1-IN-15 (Compound 72) is a selective β-secretase 1 (BACE-1) inhibitor with oral bioavailability and blood-brain barrier permeability, exhibiting an IC50 value of 121.65 nM, and an IC50 of 480.92 nM for BACE-2. BACE1-IN-15 is applicable for research in the field of Alzheimer's disease.</p>Couleur et forme :Odour SolidMR33317
<p>MR33317 is an inhibitor of acetylcholinesterase with an IC50 value of 41 nM. Additionally, it acts as an agonist for brain 5-HT4 receptors.</p>Formule :C22H28ClN3O2Masse moléculaire :401.1875β-Cholanic acid
CAS :<p>5β-Cholanic acid (5beta-Cholanic acid) is a potent γ-secretase modulator used in Alzheimer's disease research.</p>Formule :C24H40O2Degré de pureté :98.91% - 99.89%Couleur et forme :SoildMasse moléculaire :360.57NF023 hexasodium
CAS :<p>NF023 hexasodium is a selective and competitive P2X1 receptor antagonist, with IC50 values of 0.21 μM, 28.9 μM, > 50 μM and > 100 μM for human P2X1, P2X3, P2X2</p>Formule :C35H26N4Na6O21S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1168.92α-Conotoxin PIA TFA
<p>α-Conotoxin PIA TFA, targeting nicotinic acetylcholine receptor (nAChR) subtypes with α6 and α3 subunits, acts as an antagonist.</p>Formule :C81H126F3N27O27S4Degré de pureté :98.81%Couleur et forme :SolidMasse moléculaire :2095.3(S)-AMPA HCl
<p>(S)-AMPA HCl (L-AMPA HCl) is a selective AMPA receptor agonist with potential antidepressant activity. It can be used in research on Parkinson's disease.</p>Formule :C7H11ClN2O4Degré de pureté :99.18%Couleur et forme :SolidMasse moléculaire :222.634-fluoro MBZP
CAS :<p>4-fluoro MBZP is a novel psychoactive substance in the phenylpiperazine class, utilized for studies on the 5-HT2 receptors in the central nervous system.</p>Formule :C12H17FN2Couleur et forme :SolidMasse moléculaire :208.28AChE-IN-60
<p>AChE-IN-60 (compound 6k) is a potent inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), with IC50 values of 27 nM and 43 nM, respectively. It also inhibits monoamine oxidase MAO-A and MAO-B, with IC50 values of 353 nM and 716 nM, respectively.</p>Formule :C24H29N3O4S3Masse moléculaire :519.13202Guanylyl Imidodiphosphate (lithium salt)
CAS :<p>Guanylyl Imidodiphosphate (lithium salt) is a non-hydrolyzable GTP analog that increases adenylate cyclase activity.</p>Formule :C10H13Li4N6O13P3Couleur et forme :SolidMasse moléculaire :545.93β-Amyloid (35-25)
CAS :<p>β-Amyloid (35-25) is the reverse sequence of β-Amyloid (25-35).</p>Formule :C45H81N13O14SMasse moléculaire :1060.27mGluR5 modulator 1
CAS :<p>mGluR5 modulator 1 is a positive modulator for mGluR5, used in schizophrenia and cognitive research.</p>Formule :C18H19ClFN3O2Couleur et forme :SolidMasse moléculaire :363.82α-Casozepine
CAS :<p>α-Casozepine,Bioactive peptide from milk α-S1 casein. Binds GABA receptors. Anti-anxiety effects.</p>Formule :C60H94N14O16Couleur et forme :SolidMasse moléculaire :1267.47Asenapine citrate
CAS :<p>Asenapine citrate: atypical antipsychotic for schizophrenia, bipolar disorder; targets serotonin, adrenoceptors, dopamine, histamine (pKi: 8.2-10.5).</p>Formule :C23H24ClNO8Couleur et forme :SolidMasse moléculaire :477.89mcK6A1
<p>mcK6A1 serves as an inhibitor of amyloid-β (Aβ) aggregation, selectively binding to the 16KLVFFA21 fragment of Aβ42, leading to the formation of an extended β-sheet structure and preventing the formation of Aβ42 oligomers. This compound is valuable for research into Alzheimer's disease and other amyloid-related disorders.</p>Formule :C71H99N17O16Couleur et forme :SolidMasse moléculaire :1446.65sabcomeline
CAS :<p>Sabcomeline: potent, selective M1 agonist; boosts cognition; for Alzheimer's study.</p>Formule :C10H15N3OCouleur et forme :SolidMasse moléculaire :193.25β-Amyloid (1-28)
CAS :<p>β-Amyloid (1-28) is a β-Amyloid protein fragment involved in metal binding.</p>Formule :C145H209N41O46Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3262.51Nardoguaianone J
CAS :<p>Nardoguaianone J, a guaiane-type compound isolated from the roots of Nardostachys chinensis, has been shown to enhance SERT activity [1][2].</p>Formule :C15H22O2Couleur et forme :SolidMasse moléculaire :234.33Amyloid β-Protein (3-42)
CAS :<p>Amyloid β-Protein (3-42), the precursor of Pyr peptide, serves as the foundation of the amyloid template block in Alzheimer's disease when modified to</p>Couleur et forme :SolidBuChE-IN-13
<p>BuChE-IN-13 (compound 3) is a BuChE inhibitor that exhibits anti-Alzheimers activity. It is utilized in the research of neurodegenerative diseases.</p>Couleur et forme :Odour SolidBiotin-β-Amyloid (1-42), human TFA
<p>Biotin-β-Amyloid (1-42), human TFA, also known as Biotin-Amyloid β-Peptide (1-42) (human) TFA, is a biotin-labeled 42-amino acid peptide implicated in the</p>Formule :C215H326F3N57O64S2Couleur et forme :SolidMasse moléculaire :4854.364-Chloromethamphetamine hydrochloride
CAS :<p>4-Chloromethamphetamine hydrochloride is a novel psychoactive substance belonging to the amphetamine class.</p>Formule :C10H15Cl2NCouleur et forme :SolidMasse moléculaire :220.141,8-Cineole
CAS :<p>Eucalyptol, a natural monoterpenoid and cyclic ether found in eucalyptus species, effectively controls excessive airway mucus secretion and asthma by inhibiting pro-inflammatory cytokines. It serves as an efficacious treatment for non-purulent sinusitis, reducing inflammation and pain when applied topically, and demonstrating leukemic cell-killing capabilities in vitro.</p>Formule :C10H18ODegré de pureté :97.44% - 97.44%Couleur et forme :SolidMasse moléculaire :154.25(Glu20)-Amyloid β-Protein (1-42)
CAS :<p>(Glu20)-Amyloid β-Protein (1-42) represents a variant of amyloid β-protein (Aβ) that fibrillizes more slowly.</p>Formule :C199H309N55O62SCouleur et forme :SolidMasse moléculaire :4495.98SB-408124
CAS :<p>SB408124: Non-peptide, OX1 receptor antagonist, Ki 57 nM (whole cell) and 27 nM (membrane), 50x more selective than OX2.</p>Formule :C19H18F2N4ODegré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :356.37Brexpiprazole S-oxide D8
CAS :<p>Brexpiprazole S-oxide D8 (DM-3411 D8) is a deuterium-labeled metabolite of Brexpiprazole, a partial agonist at 5-HT1A and dopamine receptors.</p>Formule :C25H19D8N3O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :457.61Acetyl-Tau Peptide (273-284) amide
CAS :<p>Acetyl-Tau Peptide (273-284) amide inhibits Ac-Aβ(25–35)-NH2 aggregation and models Aβ/Tau interaction.</p>Formule :C64H116N18O17Couleur et forme :SolidMasse moléculaire :1409.72Orexin B, rat, mouse TFA
<p>Orexin B, rat/mouse TFA, activates OX1-R & OX2-R receptors, influencing food intake, energy, and sleep regulation.</p>Formule :C128H216F3N45O36SCouleur et forme :SolidMasse moléculaire :3050.42Zanapezil free base
CAS :<p>Zanapezil (TAK-147): potent, selective AChE inhibitor; reversible; IC50=51.2 nM; moderate M1/M2 inhibition; AD research potential.</p>Formule :C25H32N2OCouleur et forme :SolidMasse moléculaire :376.544(Met(O2)35)-Amyloid β-Protein (1-42)
<p>(Met(O2)35)-Amyloid β-Protein (1-42) is a peptide [1] .</p>Formule :C203H311N55O62SCouleur et forme :SolidMasse moléculaire :4546.04Anisatin
<p>Anisatin is a useful organic compound for research related to life sciences and the catalog number is T124719.</p>Formule :C15H20O8Couleur et forme :SolidMasse moléculaire :328.317AChE/Aβ-IN-6
<p>BACE1-IN-15 (compound 4j) serves as an effective inhibitor of BACE1 (β-secretase), efficiently mitigating the copper-induced toxicity of Aβ, with an EC50 value of 0.68 μM.</p>Couleur et forme :Odour SolidRubrofusarin triglucoside
CAS :<p>Rubrofusarin triglucoside, a glycoside from Cassia obtusifolia seeds, inhibits hMAO-A with an IC50 of 85.5 μM.</p>Formule :C33H42O20Couleur et forme :SolidMasse moléculaire :758.679
