Neuroscience
Les inhibiteurs en neurosciences sont des composés conçus pour moduler l'activité de protéines, d'enzymes ou de récepteurs spécifiques au sein du système nerveux. Ces inhibiteurs sont cruciaux pour étudier les mécanismes moléculaires sous-jacents au fonctionnement neuronal, à la transmission synaptique et aux maladies neurodégénératives. En ciblant les récepteurs des neurotransmetteurs, les canaux ioniques et les voies de signalisation, les inhibiteurs en neurosciences facilitent l'exploration du fonctionnement cérébral et le développement de stratégies thérapeutiques pour des troubles neurologiques tels que la maladie d'Alzheimer, de Parkinson et l'épilepsie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs en neurosciences de haute qualité pour soutenir vos recherches en neurobiologie, neuropharmacologie et sciences cognitives.
Sous-catégories appartenant à la catégorie "Neuroscience"
- récepteur 5-HT(940 produits)
- ACK(1 produits)
- AChR(574 produits)
- ATP Citrate Lyase(16 produits)
- Récepteur adrénergique(2.939 produits)
- BACE(36 produits)
- Bêta-amyloïde(204 produits)
- CaMK(68 produits)
- COX(562 produits)
- Récepteur de la dopamine(407 produits)
- Récepteur GABA(336 produits)
- Gamma-sécrétase(59 produits)
- GluR(255 produits)
- GlyT(24 produits)
- Récepteur de l'histamine(358 produits)
- LRRK2(33 produits)
- Récepteur de la mélatonine(24 produits)
- NMDAR(28 produits)
- Récepteur OX(40 produits)
- Récepteur opioïde(296 produits)
Affichez 12 plus de sous-catégories
5400 produits trouvés pour "Neuroscience"
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ZL-1101
<p>ZL-1101 is a human monoclonal antibody (mAb) targeting TNFRSF4/OX40/CD134.</p>Couleur et forme :Odour LiquidAChE/BChE-IN-13
<p>AChE/BChE-IN-13 (compound 5j) serves as a potent dual inhibitor of both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), exhibiting half-maximal</p>Formule :C21H18N8O7Couleur et forme :SolidMasse moléculaire :494.42Biotin-β-Amyloid (1-42), human TFA
<p>Biotin-β-Amyloid (1-42), human TFA, also known as Biotin-Amyloid β-Peptide (1-42) (human) TFA, is a biotin-labeled 42-amino acid peptide implicated in the</p>Formule :C215H326F3N57O64S2Couleur et forme :SolidMasse moléculaire :4854.36BChE-IN-16
<p>BChE-IN-16 (compound 87) is a potent inhibitor of human butyrylcholinesterase (hBChE) exhibiting an inhibition concentration half-maximum (IC50) of 3.8 nM.</p>Formule :C28H32FNO2Couleur et forme :SolidMasse moléculaire :433.56Millmerranone A
<p>Millmerranone A shows the acetylcholinesterase inhibitory property.</p>Formule :C27H28O9Couleur et forme :SolidMasse moléculaire :496.51β-Amyloid (1-11)
CAS :<p>Anionic interaction of Beta-amyloid (1-11) with Factor XII is suspected to cause massive activation of the C4 (complement 4) system in the cerebrospinal fluid</p>Formule :C56H76N16O22Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1325.3STX-107
CAS :<p>STX-107 is a potent and selective mGluR5 agonist for the study of Fragile X Syndrome.</p>Formule :C18H10FN3SDegré de pureté :99.17%Couleur et forme :SolidMasse moléculaire :319.36(Gln22)-Amyloid β-Protein (1-42)
CAS :<p>(Gln22)-Amyloid β-Protein (1-42), a Dutch mutation (E22Q) variant of β-Amyloid (1-42), demonstrates increased fibrillogenic and pathogenic characteristics [1].</p>Formule :C203H312N56O59SCouleur et forme :SolidMasse moléculaire :4513.05Substance P(1-4) Acetate
<p>Substance P(1-4) Acetate is a neurokinin receptor (NK-R) antagonist, inhibiting the formation of PV EEC.</p>Formule :C24H44N8O7Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :556.66AChE/BChE-IN-15
<p>AChE/BChE-IN-15 (Compound 6d) serves as an inhibitor for both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), presenting inhibition constants (</p>Formule :C29H30N6O3Couleur et forme :SolidMasse moléculaire :510.59CALP2
CAS :<p>CALP2 is a CaM antagonist blocking EF-hand/Ca2+ site; inhibits CaM phosphodiesterase, raises Ca2+, and activates alveolar macrophages.</p>Formule :C68H104N14O13SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1357.72(R)-(+)-Anatabine
CAS :<p>(R)-(+)-Anatabine is an less active R-enantiomer of Anatabine. Anatabine is a potent agonist of α4β2 nAChR.</p>Formule :C10H12N2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :160.22DDC 2′,3′-O-disulfate
<p>DDC 2′,3′-O-disulfate (compound 4) inhibits the fibrillization and oligomerization of Aβ42, showing promise for Alzheimer's disease (AD) research [1].</p>Formule :C17H16O11S2Couleur et forme :SolidMasse moléculaire :460.43AChE-IN-34
<p>AChE-IN-34 (compound 5l) is a potent, selective AChE inhibitor exhibiting an IC50 of 3.98 µM and negligible BChE inhibition.</p>Formule :C19H14N8O6Couleur et forme :SolidMasse moléculaire :450.36COX-2-IN-49
<p>COX-2-IN-49 (compound 6c) is a potent inhibitor of cyclooxygenase-2 (COX-2), displaying an IC50 value of 2.671 µM. This compound exhibits anti-proliferative properties and holds potential for use in cancer research.</p>Couleur et forme :Odour SolidMRS7925
<p>MRS7925 (Compound 43) serves as a potent antagonist of the 5-HT2B receptor, with an inhibition constant (Ki) of 17 nM, and is utilized in the study of fibrosis</p>Formule :C20H26IN5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :511.36AChE-IN-29
<p>AChE-IN-29, a 3-OH pyrrolidine derivative, acts as a cholinesterase (ChE) inhibitor with potent activity against human acetylcholinesterase (hAChE), electric</p>Formule :C18H19BrN2O2Couleur et forme :SolidMasse moléculaire :375.26MAO-B-IN-3
<p>MAO-B-IN-3 is a reversible, selective inhibitor of monoamine oxidase B (MAO-B) with an IC50 of 96 nM and demonstrates affinity for the 5-HT6 receptor with a Ki</p>Formule :C24H25N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :387.47GSK-3β inhibitor 27
<p>GSK-3β inhibitor27 (Compound 1c) is a reversible, competitive inhibitor of GSK-3β with an IC50 value of 2.2 μM. It inhibits tau hyperphosphorylation and reduces Aβ protein aggregation, demonstrating metal chelation and neuroprotective potential. GSK-3β inhibitor27 is promising for research into neurodegenerative diseases, such as Alzheimer's disease.</p>Formule :C16H17ClN4O2Couleur et forme :SolidMasse moléculaire :332.79AChE-IN-39
<p>AChE-IN-39 (Compound 7c), with an IC50 value of 0.058 μM, is an acetylcholinesterase (AChE) inhibitor known for its DPPH scavenging activity and potential to</p>Formule :C19H15NO3Couleur et forme :SolidMasse moléculaire :305.335-HT6 agonist 1
<p>Compound 19, a 5-HT6 agonist with an affinity (K i : 5 nM), exhibits antidepressant-like effects and enhances cognitive function while also inhibiting platelet</p>Formule :C17H22Cl2N6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :413.37(Rac)-5-Hydroxymethyl Tolterodine hydrochloride
CAS :<p>(Rac)-5-Hydroxymethyl Tolterodine HCl, or (Rac)-Desfesoterodine HCl, is a potent mAChR blocker researched for overactive bladder.</p>Formule :C22H32ClNO2Couleur et forme :SolidMasse moléculaire :377.95AChE-IN-45
<p>AChE-IN-45 (Compound 14) is an acetylcholinesterase (AChE) inhibitor exhibiting an IC50 value of 11.57±0.45 nM, and it demonstrates both antioxidant and</p>Couleur et forme :Odour SolidCUR-IPA
<p>CUR-IPA is a cholinesterase inhibitor with IC50 values of 5.99 μM for eAChE (electric eel), 59.30 μM for hAChE (human), and 60.66 μM for hBChE (human). It has free radical scavenging and antioxidant activity and is useful for researching cognitive dysfunction.</p>Formule :C43H38N2O8Couleur et forme :SolidMasse moléculaire :710.77Aβ-IN-8
<p>Aβ-IN-8, also known as compound 7e, is a potent inhibitor of Aβ aggregation [1].</p>Formule :C22H16F3N3O3SCouleur et forme :SolidMasse moléculaire :459.445-HT1AR/5-HT6R ligand-1
<p>5-HT1AR/5-HT6R ligand-1 (Compound PP13) functions as a ligand for the 5-HT receptor, demonstrating high affinity for 5-HT1AR, 5-HT6R, and 5-HT7R with Ki values of 19, 69, and 198 nM, respectively. In HEK293 cells, it inhibits cAMP production with EC50 values of 1535, 488, and 53 nM for these receptors. Additionally, 5-HT1AR/5-HT6R ligand-1 exhibits antiproliferative effects on several cancer cell lines, including 1321N1, U87MG, MCF7, and AsPC-1, with IC50 values of 9.6, 13.6, 19.3, and 14.6 μM, respectively. The compound also shows antagonistic activity towards the dopamine receptor D2R, with a Ki of 1903 nM.</p>Formule :C25H29ClN4O2SCouleur et forme :SolidMasse moléculaire :485.04BChE-IN-40
<p>BChE-IN-40 (compound D40) is a potent butyrylcholinesterase inhibitor with an IC50 of 0.59 μM. It demonstrates significant anti-inflammatory effects, with an IC50 of 4.55 μM in inhibiting nitric oxide production. Additionally, BChE-IN-40 exhibits excellent permeability across the blood-brain barrier.</p>Formule :C28H30N2O7Couleur et forme :SolidMasse moléculaire :506.2053AChE/BuChE/MAO-B-IN-2
<p>AChE/BuChE/MAO-B-IN-2 (compound 4b) is a potent inhibitor of AChE, BuChE, and hu MAO-B, with respective IC50 values of 5.3 μM, 12.4 μM, and 1.9±0.08 μM,</p>Formule :C19H18FNO3Couleur et forme :SolidMasse moléculaire :327.35β-Amyloid (10-20)
CAS :<p>Amyloid β-Protein (10-20) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Amyloid β protein fragment containing the α-</p>Formule :C71H99N17O16Degré de pureté :98%Couleur et forme :Lyophilized PowderMasse moléculaire :1446.65BACE1-IN-15
<p>BACE1-IN-15 (Compound 72) is a selective β-secretase 1 (BACE-1) inhibitor with oral bioavailability and blood-brain barrier permeability, exhibiting an IC50 value of 121.65 nM, and an IC50 of 480.92 nM for BACE-2. BACE1-IN-15 is applicable for research in the field of Alzheimer's disease.</p>Couleur et forme :Odour SolidNipecotic acid
CAS :<p>Compound PDK0243, with CAS No. 498-95-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0243 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Formule :C6H11NO2Couleur et forme :Off-White To Pale Yellow-Beige PowderMasse moléculaire :129.16CVN417
<p>CVN417 is an orally active antagonist of nAChR containing the α6 subunit, modulating phasic dopaminergic neurotransmission in an impulse-dependent fashion.</p>Couleur et forme :Odour SolidGABAA receptor modulator-3
<p>GABAA receptor modulator-3 (compound 3b) is a positive allosteric modulator (PAM). It inhibits the peak current and steady-state current of α1β3γ2 GABAAR with IC50 values of 671 μM and 64 μM, respectively.</p>Formule :C18H22O2Couleur et forme :SolidMasse moléculaire :270.37JH-XII-03-02
CAS :<p>JH-XII-03-02 is a potent and selective leucine-rich repeat kinase 2 (LRRK2) proteolysis targeting chimera (PROTAC) degrader, utilized in Parkinson's Disease (PD</p>Formule :C43H51N9O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :853.92Calmodulin Binding Peptide 1
CAS :<p>Calmodulin Binding Peptide 1, a high-affinity MLCK-derived inhibitor, blocks IP3-induced Ca2+ release.</p>Formule :C231H373N69O70S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :5301.1γ-Secretase modulator 10
CAS :<p>γ-Secretase modulator 10 is a novel γ-secretase modulator.</p>Formule :C25H23F3N4O2Couleur et forme :SolidMasse moléculaire :468.48TIP 39, Tuberoinfundibular Neuropeptide
CAS :<p>TIP39 is a synthetic neuropeptide agonist for human and rat PTH2 receptors from the hypothalamus.</p>Formule :C202H325N61O54SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :4504.2TC-2559 difumarate
CAS :<p>TC-2559 difumarate: Oral α4β2 nAChR partial agonist, CNS-selective, EC50 0.18 μM, prefers α4β2 over α2β4/α4β4/α3β4, antinociceptive.</p>Formule :C20H26N2O9Couleur et forme :SolidMasse moléculaire :438.43AChE-IN-86
<p>AChE-IN-86 (Compound 6f) is an inhibitor of acetylcholinesterase (AChE) with an IC50 value of 25.33 μg/mL. This compound exerts its inhibitory effects by forming hydrogen bonds, π-π, and π-alkyl interactions with amino acid residues at the key catalytic site of AChE. AChE-IN-86 can be utilized in Alzheimer's disease research.</p>Formule :C28H27N3O6SCouleur et forme :SolidMasse moléculaire :533.595LY-53857 free base
CAS :<p>LY-53857 free base is a bioactive chemical.</p>Formule :C23H32N2O3Couleur et forme :SolidMasse moléculaire :384.51Atracurium
CAS :<p>Atracurium (BW-33A) is a competitive AChR antagonist and non-depolarizing muscle relaxant that may cause bronchoconstriction.</p>Formule :C53H72N2O122Couleur et forme :SolidMasse moléculaire :929.14(Iso)-Landipirdine
CAS :<p>(Iso)-Landipirdine((Iso)-RO5025181) is a selective and potent 5-HT6R antagonist.</p>Formule :C18H19FN2O3SDegré de pureté :98.50%Couleur et forme :SoildMasse moléculaire :362.42Bis-(-)-8-demethylmaritidine
<p>Bis-(-)-8-demethylmaritidine, a natural alkaloid, serves as a potent inhibitor of acetylcholinesterase (AChE) and is utilized in Alzheimer's disease research [1</p>Couleur et forme :Odour SolidDeoxynojirimycin Tetrabenzyl Ether
CAS :<p>Deoxynojirimycin tetrabenzyl ether aids in making 1-dNM, a strong α-glucosidase I & II blocker.</p>Formule :C34H37NO4Couleur et forme :SolidMasse moléculaire :523.673N-Methylcyclohexaneethaneamine
CAS :<p>N-Methylcyclohexaneethaneamine is a useful organic compound for research related to life sciences.</p>Formule :C9H19NCouleur et forme :SolidMasse moléculaire :141.2539DCCCyb
CAS :<p>DCCCyb: oral GlyT1 inhibitor with high in vivo occupancy in rhesus monkeys, confirmed by PET tracer displacement.</p>Formule :C22H29Cl2NO3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :458.44K1833
<p>K1833 is an inhibitor and reactivator of human acetylcholinesterase (hrAChE), exhibiting an inhibition concentration (IC50) of 58$.</p>Couleur et forme :Odour SolidMesoridazine Besylate
CAS :<p>Mesoridazine Besylate (Serentil), a piperidine antipsychotic and phenothiazine, treats schizophrenia; it's a thioridazine metabolite.</p>Formule :C27H32N2O4S3Degré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :544.75Mosapride citrate dihydrate
CAS :<p>Mosapride Citrate, a 5-HT4 agonist, boosts gut movement by enhancing acetylcholine release.</p>Formule :C27H35ClFN3O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :632.04hAChE-IN-5
<p>hAChE-IN-5 (compound 49) is a dual inhibitor of human acetylcholinesterase (hAChE) and human butyrylcholinesterase (hBuChE), exhibiting inhibitory potency with</p>Degré de pureté :98%Couleur et forme :Odour Solid
