Neuroscience
Les inhibiteurs en neurosciences sont des composés conçus pour moduler l'activité de protéines, d'enzymes ou de récepteurs spécifiques au sein du système nerveux. Ces inhibiteurs sont cruciaux pour étudier les mécanismes moléculaires sous-jacents au fonctionnement neuronal, à la transmission synaptique et aux maladies neurodégénératives. En ciblant les récepteurs des neurotransmetteurs, les canaux ioniques et les voies de signalisation, les inhibiteurs en neurosciences facilitent l'exploration du fonctionnement cérébral et le développement de stratégies thérapeutiques pour des troubles neurologiques tels que la maladie d'Alzheimer, de Parkinson et l'épilepsie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs en neurosciences de haute qualité pour soutenir vos recherches en neurobiologie, neuropharmacologie et sciences cognitives.
Sous-catégories appartenant à la catégorie "Neuroscience"
- récepteur 5-HT(940 produits)
- ACK(1 produits)
- AChR(574 produits)
- ATP Citrate Lyase(16 produits)
- Récepteur adrénergique(2.942 produits)
- BACE(36 produits)
- Bêta-amyloïde(204 produits)
- CaMK(68 produits)
- COX(562 produits)
- Récepteur de la dopamine(407 produits)
- Récepteur GABA(336 produits)
- Gamma-sécrétase(59 produits)
- GluR(255 produits)
- GlyT(24 produits)
- Récepteur de l'histamine(358 produits)
- LRRK2(33 produits)
- Récepteur de la mélatonine(24 produits)
- NMDAR(28 produits)
- Récepteur OX(40 produits)
- Récepteur opioïde(296 produits)
Affichez 12 plus de sous-catégories
5400 produits trouvés pour "Neuroscience"
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GABAA receptor modulator-3
<p>GABAA receptor modulator-3 (compound 3b) is a positive allosteric modulator (PAM). It inhibits the peak current and steady-state current of α1β3γ2 GABAAR with IC50 values of 671 μM and 64 μM, respectively.</p>Formule :C18H22O2Couleur et forme :SolidMasse moléculaire :270.37Imagabalin
CAS :<p>Imagabalin is an active compound used in the study of neurological diseases.</p>Formule :C9H19NO2Couleur et forme :SolidMasse moléculaire :173.25Multitarget AD inhibitor-1
CAS :<p>Multitarget AD inhibitor-1: reversible, selective BuChE blocker, inhibits β-secretase and amyloid/tau aggregation, promising for Alzheimer's research.</p>Formule :C29H38N2OCouleur et forme :SolidMasse moléculaire :430.636MGS0028
CAS :<p>MGS0028 is a selective agonist of metabotropic glutamate 2/3 receptor, it could reverse abnormal behaviors in mice induced by isolation rearing.</p>Formule :C8H8FNO5Couleur et forme :SolidMasse moléculaire :217.15β-Amyloid (35-42)
CAS :<p>β-Amyloid (35-42) is a peptide derived from the beta-amyloid protein, encompassing amino acids 35 through 42.</p>Formule :C33H60N8O9SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :744.94Mirtazapine N-oxide
CAS :<p>Mirtazapine N-oxide, a mirtazapine metabolite, is produced by CYP1A2 and CYP3A4 in human liver.</p>Formule :C17H19N3OCouleur et forme :SolidMasse moléculaire :281.359BuChE-IN-21
<p>BuChE-IN-21 (compound SXF3) is a potent and selective inhibitor of BuChE, demonstrating inhibitory effects on eqBuChE and hBuChE with IC50 values of 0.05 and 0.04 μM, respectively. Additionally, BuChE-IN-21 exhibits significant anti-inflammatory activity.</p>Formule :C16H23NO2Couleur et forme :SolidMasse moléculaire :261.172885-HT2A receptor agonist-5
CAS :<p>5-HT2A receptor agonist-5 (compound I-3) is a potent 5-HT2A agonist with a Ki value of 0.017 µM and exhibits antidepressant activity.</p>Formule :C23H29N3OCouleur et forme :SolidMasse moléculaire :363.5Antidepressant agent 4
<p>Antidepressant agent 4: orally active, has antidepressant, anxiolytic, and nootropic effects.</p>Formule :C19H38ClN5O2SCouleur et forme :SolidMasse moléculaire :436.06β-Amyloid (11-22)
CAS :<p>β-Amyloid (11-22) is a peptide fragment of β-Amyloid.Beta-amyloid peptide (Abeta), the major constituent of amyloid plaques in the brains of Alzheimer’s</p>Formule :C70H102N18O18Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1483.67M 8218
CAS :<p>M 8218 is a bioactive chemical.</p>Formule :C20H29NO2Couleur et forme :SolidMasse moléculaire :315.452-Methyl-1-indanone
CAS :<p>2-Methyl-1-indanone is an acetylcholinesterase inhibitor and can be used for biochemical experiments and drug synthesis.</p>Formule :C10H10ODegré de pureté :96.6%Couleur et forme :SolidMasse moléculaire :146.19SSAO inhibitor-1
CAS :<p>SSAO Inhibitor-1 blocks SSAO, has anti-inflammatory effects, used in liver disease research.</p>Formule :C17H24FN5O2Couleur et forme :SolidMasse moléculaire :349.41GABAA receptor modulator-4
<p>GABAA receptor modulator-4 (Compound 4) acts as a negative allosteric modulator of the GABAA receptor. It inhibits the peak and steady-state currents mediated by the α1β3γ2 GABAA receptors, with an IC50 of 10 μM for both.</p>Formule :C15H17BrO4SCouleur et forme :SolidMasse moléculaire :373.26Sintamil
CAS :<p>Sintamil is a useful organic compound for research related to life sciences. The catalog number is T71697 and the CAS number is 16398-39-3.</p>Formule :C18H20ClN3O4Couleur et forme :SolidMasse moléculaire :377.82p-HTAA
CAS :<p>Pentamer Hydrogen Thiophene Acetic Acid (p-HTAA) is a compound that specifically targets and labels amyloid-beta (Aβ) deposits in the brains of living mice [1].</p>Formule :C24H16O4S5Couleur et forme :SolidMasse moléculaire :528.71Cannabidiolic acid methyl ester
CAS :<p>Cannabidiolic acid methyl ester (HU-580) is an orally active analogue of cannabidiolic acid. It enhances the activation of 5-HT1A receptors and increases the expression of c-Fos and NeuN in specific hypothalamic nuclei in rats. Cannabidiolic acid methyl ester exhibits anti-nausea, anxiolytic, and anti-nociceptive effects.</p>Formule :C23H32O4Couleur et forme :SolidMasse moléculaire :372.5Laniquidar TFA
<p>Laniquidar TFA (R101933), a non-competitive P-gp inhibitor, has an IC50 of 0.51 μM; used to study AML and MDS, but with limited bioavailability.</p>Formule :C39H37F3N4O5Degré de pureté :99.85%Couleur et forme :SoildMasse moléculaire :698.73Nardoguaianone J
CAS :<p>Nardoguaianone J, a guaiane-type compound isolated from the roots of Nardostachys chinensis, has been shown to enhance SERT activity [1][2].</p>Formule :C15H22O2Couleur et forme :SolidMasse moléculaire :234.33SB656104
CAS :<p>SB656104 is a bioactive chemical.</p>Formule :C25H30ClN3O3SCouleur et forme :SolidMasse moléculaire :488.04Blestrin D
CAS :<p>Blestrin D: BChE mixed-type inhibitor, IC50=8.1μM, from Bletilla striata, for AD research.</p>Formule :C30H24O6Couleur et forme :SolidMasse moléculaire :480.51YS-370
CAS :<p>YS-370 orally blocks P-gp, moderately inhibits CYP3A4, reverses drug resistance, and enhances paclitaxel's anticancer effects.</p>Formule :C37H35BrN4O3Degré de pureté :98.055%Couleur et forme :SolidMasse moléculaire :663.6Neocarzinostatin
CAS :<p>Neocarzinostatin is an effective DNA-damaging, anti-tumor antibiotic.</p>Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :N/AMethalthiazide
CAS :<p>Methalthiazide enhances the activity of natural agonists of AMPA receptors and can be utilized in schizophrenia research.</p>Formule :C12H16ClN3O4S3Couleur et forme :SolidMasse moléculaire :397.92FRM-024
CAS :<p>FRM-024 is a powerful gamma secretase modulator with the ability to penetrate the central nervous system (CNS), designed specifically for the treatment of</p>Formule :C22H22ClN5O2Couleur et forme :SolidMasse moléculaire :423.9epi-Aszonalenin A
CAS :<p>epi-Aszonalenin A: a psychoactive benzodiazepine from Aspergillus novofumigatus.</p>Formule :C25H25N3O3Couleur et forme :SolidMasse moléculaire :415.48β-Amyloid (13-27)
CAS :<p>β-Amyloid (13-27) is a peptide consisting of amino acid of 13 to 27 of beta amyloid protein.</p>Formule :C84H126N24O24Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1856.05β-Amyloid (1-16)
CAS :<p>β-Amyloid (1-16) is an amyloidogenic protein fragment with a sequence derived from β-amyloid.</p>Formule :C84H119N27O28Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1955.045-HT5AR/5-HT6R ligand-1
<p>5-HT5AR/5-HT6R ligand-1 (Compound PP10) is a ligand for serotonin receptors, exhibiting high affinity for the 5-HT5A and 5-HT6 receptors with Ki values of 59 nM and 96 nM, respectively. It possesses some antiproliferative activity against tumor cells and can be utilized in cancer research.</p>Formule :C25H30N4O2SCouleur et forme :SolidMasse moléculaire :450.65-HT6R antagonist 6
<p>5-HT6R antagonist 6 (Compound PP15) exhibits high affinity and selectivity for the 5-HT6R receptor, with a Ki of 42 nM. It demonstrates weak antiproliferative activity on tumor cells and low toxicity toward normal cells. 5-HT6R antagonist 6 is applicable in tumor research.</p>Formule :C24H26N4O2SCouleur et forme :SolidMasse moléculaire :434.55α-Conotoxin PIA
CAS :<p>Selective antagonist of α6-containing nicotinic receptors that discriminates between the closely related α6 and α3 subunits (IC50 values are 0.95 and 74.2 nM</p>Formule :C79H125N27O25S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1981.3LY 293284
CAS :<p>LY 293284 is a potent, selective full agonist of 5-HT1A receptor with anxiogenic effects in animal studies.</p>Formule :C19H26N2OCouleur et forme :SolidMasse moléculaire :298.42JF-NP-26
<p>Releases pain-blocking raseglurant under 405 nm light. Inhibits Quisqualate. Analgesic in vivo. Quantum yield: 0.18.</p>Couleur et forme :SolidZicronapine fumarate
CAS :<p>Zicronapine fumarate, an antipsychotic, targets D1/D2 & 5-HT2A receptors; may treat neuropsychiatric conditions.</p>Formule :C26H31ClN2O4Couleur et forme :SolidMasse moléculaire :470.99Velnacrine
CAS :<p>Velnacrine (1,2,3,4-tetrahydro-9-aminoacridin-1-ol maleate) is a biochemical.</p>Formule :C13H14N2ODegré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :214.264-Iodoamphetamine hydrochloride
CAS :<p>4-Iodoamphetamine (p-Iodoamphetamine) hydrochloride is a halogenated phenethylamine characterized by the presence of an iodine atom at the para position of the phenyl group. It selectively induces serotonin release and inhibits reuptake in rat brain synaptosomes.</p>Formule :C9H13ClINCouleur et forme :SolidMasse moléculaire :297.56I2-IRs ligand-1
<p>I2-IRs ligand-1 (Compound 12d) is an orally active compound capable of crossing the blood-brain barrier. It exhibits high affinity for imidazoline I2 receptors (I2-IRs) with a pKi of 9.98. This compound can enhance cognitive deficits in aging mice and possesses analgesic, anti-inflammatory, and neuroprotective properties. I2-IRs ligand-1 is applicable for research in Alzheimer's disease and related pain disorders.</p>Formule :C21H23ClFN2O4PCouleur et forme :SolidMasse moléculaire :452.84Melatonin-Tamoxifen Conjugate
<p>Melatonin-Tamoxifen Conjugate (compound 16c) is an anticancer drug conjugate made of Melatonin and Tamoxifen, serving as an effective antagonist of ERα (IC50 = 863 nM). In cells expressing the hMT1 receptor, it binds to MLT receptors (Ki = 3.1 nM) and exhibits the ability to promote β-arrestin activation (EC50 = 914 nM) and ERK activation (EC50 = 98 nM). The IC50 values for Melatonin-Tamoxifen Conjugate in MCF-7, MDA-MB-231, and HT-1080 cell lines are 6.8 μM, 6.4 μM, and 1.7 μM, respectively.</p>Formule :C47H58N4O4Couleur et forme :SolidMasse moléculaire :742.99Stacofylline
CAS :<p>Stacofylline is a xanthine derivative that is used to treat migraine headaches.</p>Formule :C20H33N7O3Degré de pureté :99.54% - >99.99%Couleur et forme :SolidMasse moléculaire :419.52DCCCyb
CAS :<p>DCCCyb: oral GlyT1 inhibitor with high in vivo occupancy in rhesus monkeys, confirmed by PET tracer displacement.</p>Formule :C22H29Cl2NO3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :458.44Jatrorrhizine hydroxide
CAS :<p>Jatrorrhizine hydroxide: alkaloid from Coptis chinensis; neuroprotective, antimicrobial, antiplasmodial, antioxidant; AChE inhibitor, affects 5-HT/NE uptake.</p>Formule :C20H21NO5Couleur et forme :SolidMasse moléculaire :355.38VU6028418
CAS :<p>VU6028418 is a highly selective, potent, orally active M4mAChR antagonist that acts on hM4 (IC50: 4.1 nM).</p>Couleur et forme :SolidN-Desmethyl Pimavanserin
CAS :<p>N-Desmethyl Pimavanserin (AC-279) is the active metabolite of Pimavanserin and is used in the treatment of insomnia and other sleep disorders.</p>Formule :C24H32FN3O2Degré de pureté :98.02%Couleur et forme :SolidMasse moléculaire :413.53XL01126
<p>XL01126 degrades LRRK2 (DC50: 14 nM G2019S, 32 nM WT), crosses the blood-brain barrier, aiding Parkinson's studies.</p>Formule :C50H64ClFN10O6S2Couleur et forme :SolidMasse moléculaire :1019.69Timegadine hydrochloride
CAS :<p>Timegadine hydrochloride (SR1368 hydrochloride) is the hydrochloride salt form of Timegadine. It is an orally active inhibitor of COX and lipo-oxygenase, effectively suppressing COX in rabbit platelets and rat brain with IC50 values of 5 nM and 20 μM, respectively, and inhibiting lipo-oxygenase in horse and rabbit platelets with an IC50 of 100 μM. Timegadine hydrochloride also exhibits anti-arthritis activity.</p>Formule :C20H24ClN5SCouleur et forme :SolidMasse moléculaire :401.96TRV-7019
CAS :<p>TRV-7019: BBB-permeable radioligand for brain imaging, used in diagnosing amyloid diseases, MS, and brain tumors.</p>Formule :C14H12INO3Couleur et forme :SolidMasse moléculaire :369.15Mant-GTPγS
CAS :<p>Mant-GTPγS, an effective GTP analog, displays strong competitive inhibition of adenylyl cyclase (AC). Additionally, it acts as a potent inhibitor of YdeH.</p>Formule :C18H23N6O14P3SCouleur et forme :SolidMasse moléculaire :672.39Endosulfan I
CAS :<p>Endosulfan I is one of the two major stereoisomers of the broad-spectrum insecticide Endosulfan inhibi the GABA/benzodiazepine/picrotoxin complex</p>Formule :C9H6Cl6O3SDegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :406.93Vortioxetine D8
CAS :<p>Vortioxetine D8 is a deuterium-labeled antidepressant inhibiting 5-HT1A/B, 5-HT3A, 5-HT7 receptors & SERT (Ki: 15-1.6 nM).</p>Formule :C18H22N2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :306.5(R)-Citalopram oxalate
CAS :<p>(R)-Citalopram oxalate is a weak selective serotonin reuptake inhibitor (SSRI) that antagonises its S-isomer (escitalopram), anticonvulsant and antidepressant</p>Formule :C22H23FN2O5Degré de pureté :99.76%Couleur et forme :White SolidMasse moléculaire :414.43
