Neuroscience
Les inhibiteurs en neurosciences sont des composés conçus pour moduler l'activité de protéines, d'enzymes ou de récepteurs spécifiques au sein du système nerveux. Ces inhibiteurs sont cruciaux pour étudier les mécanismes moléculaires sous-jacents au fonctionnement neuronal, à la transmission synaptique et aux maladies neurodégénératives. En ciblant les récepteurs des neurotransmetteurs, les canaux ioniques et les voies de signalisation, les inhibiteurs en neurosciences facilitent l'exploration du fonctionnement cérébral et le développement de stratégies thérapeutiques pour des troubles neurologiques tels que la maladie d'Alzheimer, de Parkinson et l'épilepsie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs en neurosciences de haute qualité pour soutenir vos recherches en neurobiologie, neuropharmacologie et sciences cognitives.
Sous-catégories appartenant à la catégorie "Neuroscience"
- récepteur 5-HT(1.025 produits)
- ACK(1 produits)
- AChR(645 produits)
- ATP Citrate Lyase(17 produits)
- Récepteur adrénergique(3.018 produits)
- BACE(37 produits)
- Bêta-amyloïde(228 produits)
- CaMK(73 produits)
- COX(600 produits)
- Récepteur de la dopamine(445 produits)
- Récepteur GABA(372 produits)
- Gamma-sécrétase(61 produits)
- GluR(265 produits)
- GlyT(26 produits)
- Récepteur de l'histamine(385 produits)
- LRRK2(43 produits)
- Récepteur de la mélatonine(26 produits)
- NMDAR(10 produits)
- Récepteur OX(41 produits)
- Récepteur opioïde(327 produits)
Affichez 12 plus de sous-catégories
5523 produits trouvés pour "Neuroscience"
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JNJ-67569762
CAS :JNJ-67569762 is a selective BACE1 inhibitor targeting the S3 pocket ( IC 50 = 2.7 nM).Formule :C22H22F4N4O5SCouleur et forme :SolidMasse moléculaire :530.49bPiDDB
CAS :bPiDDB (N,N'-Dodecylbis-Picolinium Bromide) is a nicotinic receptor (nAChR) antagonist.
Formule :C24H38Br2N2Degré de pureté :98.72%Couleur et forme :SolidMasse moléculaire :514.385-HT2C agonist-4
CAS :Compound 3i, a 5-HT2C agonist-4, acts as an agonist for the 5-HT2C receptor with an EC50 of 5.7 nM. It is capable of reducing locomotor activity in zebrafish larvae.Formule :C24H25N5OCouleur et forme :SolidMasse moléculaire :399.49DOAM
CAS :DOAM is an antagonist of the 5-HT2 receptor.Formule :C16H27NO2Couleur et forme :SolidMasse moléculaire :265.394-Methoxyphenyl isothiocyanate
CAS :4-Methoxyphenyl isothiocyanate (4-Methylphenyl ITC) is recognized as an antioxidant demonstrating an IC50 of 1.25 mM for scavenging DPPH free radicals. Its antioxidant capacity, as shown by the ORAC test, is 11.7 mM TE, equivalent to the efficacy of 11.7 mmol Trolox under similar conditions. Additionally, it extends the oxidation process in the Briggs–Rauscher reaction by approximately 9180 seconds. The compound also exhibits moderate cholinesterase inhibitory activity, with an inhibition rate of 30.4% for acetylcholinesterase (AChE) and 17.9% for butyrylcholinesterase (BChE). Research suggests 4-Methoxyphenyl isothiocyanate holds promise for applications in antioxidant and neurological disorder studies.Formule :C8H7NOSCouleur et forme :SolidMasse moléculaire :165.21C18 L-erythro Ceramide (d18:1/18:0)
CAS :C18 L-erythro Ceramide, a natural stereoisomer, inhibits rat brain mt-CDase with IC50 of 8.8 μM.Formule :C36H71NO3Couleur et forme :SolidMasse moléculaire :565.95(1S,3R)-3-Aminocyclopentane carboxylic acid
CAS :(1S,3R)-3-Aminocyclopentane carboxylic acid exhibits activity on GABAA receptors.Formule :C6H11NO2Couleur et forme :SolidMasse moléculaire :129.16Triazolomethylindole-3-acetic acid
CAS :Triazolomethylindole-3-acetic acid is a metabolite of Rizatriptan, which acts as an agonist for the serotonin (5-HT) receptor subtypes 5-HT1B and 5-HT1D.Formule :C13H12N4O2Couleur et forme :SolidMasse moléculaire :256.262-Methyl-N,N-dimethyltryptamine
CAS :2-Methyl-N,N-dimethyltryptamine (2,N,N-TMT, compound 15) exhibits binding affinity for the serotonin (5-HT) receptor, with a pA2 value of 6.04. It plays a significant role in neurological disease research.Formule :C13H18N2Couleur et forme :SolidMasse moléculaire :202.3Zalospirone
CAS :Zalospirone is a 5-HT1A receptor agonist that can be used to study anxiety disorders and major depressive disorder.Formule :C24H29N5O2Degré de pureté :98.24% - 99.82%Couleur et forme :SolidMasse moléculaire :419.52Cannabidiolic acid methyl ester
CAS :Cannabidiolic acid methyl ester (HU-580) is an orally active analogue of cannabidiolic acid. It enhances the activation of 5-HT1A receptors and increases the expression of c-Fos and NeuN in specific hypothalamic nuclei in rats. Cannabidiolic acid methyl ester exhibits anti-nausea, anxiolytic, and anti-nociceptive effects.Formule :C23H32O4Couleur et forme :SolidMasse moléculaire :372.55-HT2A receptor agonist-5
CAS :5-HT2A receptor agonist-5 (compound I-3) is a potent 5-HT2A agonist with a Ki value of 0.017 µM and exhibits antidepressant activity.Formule :C23H29N3OCouleur et forme :SolidMasse moléculaire :363.5Furosemide sodium
CAS :Furosemide sodium: potent NKCC inhibitor, loop diuretic, treats heart failure, hypertension, edema, selective GABAA antagonist.Formule :C12H10ClN2NaO5SDegré de pureté :99.52% - >99.99%Couleur et forme :SolidMasse moléculaire :352.73Paynantheine
CAS :Paynantheine is an alkaloid with antinociceptive properties, found in Mitragyna speciosa. It also acts as an agonist at 5-HT1AR and 5-HT2BR receptors, inducing lower lip contraction and providing antinociception in rats.Formule :C23H28N2O4Couleur et forme :SolidMasse moléculaire :396.48Nitrazolam
CAS :Nitrazolam is a benzodiazepine compound that may exhibit central nervous system depressant properties similar to traditional benzodiazepine drugs by acting on the GABA receptors (GABA receptor). These effects include sedation, hypnosis, anxiolytic, and anticonvulsant activities.Formule :C17H13N5O2Couleur et forme :SolidMasse moléculaire :319.32SB-408124
CAS :SB408124: Non-peptide, OX1 receptor antagonist, Ki 57 nM (whole cell) and 27 nM (membrane), 50x more selective than OX2.Formule :C19H18F2N4ODegré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :356.37α-Conotoxin PIA TFA
α-Conotoxin PIA TFA, targeting nicotinic acetylcholine receptor (nAChR) subtypes with α6 and α3 subunits, acts as an antagonist.Formule :C81H126F3N27O27S4Degré de pureté :98.81%Couleur et forme :SolidMasse moléculaire :2095.35β-Cholanic acid
CAS :5β-Cholanic acid (5beta-Cholanic acid) is a potent γ-secretase modulator used in Alzheimer's disease research.
Formule :C24H40O2Degré de pureté :98.91% - 99.89%Couleur et forme :SoildMasse moléculaire :360.57TAT-CN21
TatCN21, with an IC 50 of 77 nM, serves as a potent and selective inhibitor peptide of the calcium/calmodulin-dependent protein kinase II (CaMKII), a ubiquitously-expressed multifunctional serine/threonine protein kinase. It is particularly useful in research pertaining to ischemia and neurodegenerative diseases.Formule :C169H303N69O43Couleur et forme :SolidMasse moléculaire :3989.65α-Casozepine
CAS :α-Casozepine,Bioactive peptide from milk α-S1 casein. Binds GABA receptors. Anti-anxiety effects.Formule :C60H94N14O16Couleur et forme :SolidMasse moléculaire :1267.47Aloveroside A
CAS :Aloveroside A, a triglucosylnaphthalene derivative extracted from Aloe vera using ethanol, exhibits modest inhibitory activity against bACE, demonstratingFormule :C30H40O17Couleur et forme :SolidMasse moléculaire :672.63Camlipixant
CAS :Camlipixant (BLU-5937) is an orally active purine P2X3 receptor antagonist that is potent, selective and competitive.
Formule :C23H24F2N4O4Degré de pureté :99.37%Couleur et forme :SoildMasse moléculaire :458.46Serazapine
CAS :Serazapine is a highly specific serotonin (5-HT2) binding inhibitor with anxiolytic activity for the treatment of anxiety disorders.
Formule :C22H23N3O2Degré de pureté :98.71% - 99.57%Couleur et forme :SolidMasse moléculaire :361.44Oxatomide
CAS :Oxatomide: Dual H1/P2X7 antagonist, antihistamine, anti-allergic, treats immune diseases, IC50: 0.95 μM (P2X7), 0.43 μM (5-HT).Formule :C27H30N4ODegré de pureté :99.28% - 99.72%Couleur et forme :White PowderMasse moléculaire :426.55Ref: TM-T19839
1mg35,00€5mg75,00€10mg114,00€25mg222,00€50mg356,00€100mg557,00€500mg1.153,00€1mL*10mM (DMSO)84,00€Adatanserin hydrochloride
CAS :Adatanserin hydrochloride (WY50324 hydrochloride) is a 5-HT(1A)/5-HT(2) receptor ligand that is neuroprotective and may be used in the study of depression.Formule :C21H32ClN5ODegré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :405.96(Rac)-Norcisapride
CAS :Norcisapride, a 5-HT3 and 5-HT4 agonist, treats GI, orofacial, and ENT disorders.Formule :C14H20ClN3O3Degré de pureté :99.32%Couleur et forme :SoildMasse moléculaire :313.78Pozanicline hydrochloride
Pozanicline hydrochloride is an oral α4β2 nAChR agonist with a 16.7 nM Ki, insignificantly binding to α7 nAChR.Formule :C11H17ClN2ODegré de pureté :97.13% - 99.81%Couleur et forme :SolidMasse moléculaire :228.72Ref: TM-T16563L
1mg73,00€5mg146,00€10mg208,00€25mg319,00€50mg447,00€100mg600,00€200mg808,00€1mL*10mM (DMSO)127,00€Mosapride citrate dihydrate
CAS :Mosapride Citrate, a 5-HT4 agonist, boosts gut movement by enhancing acetylcholine release.Formule :C27H35ClFN3O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :632.04SIB 1553A
CAS :SIB 1553A is an agonist of nAChRs, a cognitive enhancer that can be used to study diseases associated with neurodegeneration.Formule :C13H19NOSDegré de pureté :99.79%Couleur et forme :SoildMasse moléculaire :237.36Tiflucarbine
CAS :Tiflucarbine is a potential non-selective 5-HT agonist with antidepressant activity.Tiflucarbine dose-dependently increased the specific activity of solubleFormule :C16H17FN2SDegré de pureté :97.71%Couleur et forme :SolidMasse moléculaire :288.38Neuroprotective Compound Library
A unique collection of xnum bioactive small molecules with neuroprotective relevance for high throughput screening (HTS) and high content screening (HCS);
Couleur et forme :Odour Solid(±)-Acetylcarnitine chloride
CAS :(±)-Acetylcarnitine chloride (Acetyl dl-carnitine chloride) is a weak cholinergic agonist with neuroprotective properties and can be used in studies of neuritis.
Formule :C9H18ClNO4Degré de pureté :99.98%Couleur et forme :White Crystalline PowderMasse moléculaire :239.71H-Indole-3-carboxylic acid, 5-[2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]propoxy]-2-methyl-1-(4-methylphenyl)-, ethyl ester
CAS :Compound 5936-0108对β-淀粉样蛋白可能具有调节作用。
Formule :C26H34N2O7Degré de pureté :99.44%Couleur et forme :SoildMasse moléculaire :486.56Sodium Channel Targeted Library
A unique collection of xnum sodium channel blockers and agonists for high throughput and high content screening;Couleur et forme :Odour SolidRef: TM-L7400
1mgÀ demander30μL*10mM (DMSO)À demander50μL*10mM (DMSO)À demander100μL*10mM (DMSO)À demander250μL*10mM (DMSO)À demander(S)-3,4-DCPG
CAS :(S)-3,4-DCPG ((S)-3,4-Dicarboxyphenylglycine) is a selective agonist of human metabotropic glutamate receptor 8a (mGluR8a).Formule :C10H9NO6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :239.18AC1-IN-1
CAS :AC1-IN-1 is a selective inhibitor of adenylyl cyclase type 1 (AC1, IC50 = 0.54 µM).
Formule :C18H18FN5O2Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :355.37Neuronal Signaling Compound Library
A unique collection of xnum compounds targeting CNS signaling for high throughput screening (HTS) and high content screening (HCS) for new drugs;Couleur et forme :Odour SolidRef: TM-L2600
1mgÀ demander30μL*10mM (DMSO)À demander50μL*10mM (DMSO)À demander100μL*10mM (DMSO)À demander250μL*10mM (DMSO)À demander3-Aminopropylphosphonic Acid
CAS :3-aminopropylphosphonic acid (3-APPA) is a phosphonic analog of GABA that acts as a partial agonist of GABAB receptors (IC50 = 1.5 μM in a radioligand binding
Formule :C3H10NO3PDegré de pureté :99.84%Couleur et forme :Light Yellow LiquidMasse moléculaire :139.09Aducanumab
CAS :Aducanumab (BIIB037) is an IgG1 antibody targeting amyloid beta to treat Alzheimer's; it's brain-permeable.
Degré de pureté :95% - 97.10%Couleur et forme :LiquidMasse moléculaire :145.93 kDa1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-
CAS :1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)- is a low activity isomer of S 18986.Formule :C10H12N2O2SDegré de pureté :99.96%Couleur et forme :SoildMasse moléculaire :224.28(+)-OSU 6162
CAS :(+)-OSU 6162 (Piperidine, 3-[3-(methylsulfonyl)phenyl]-1-propyl-, (3R)-) is an agonist of 5-HT Receptor with anti-Alzheimer and antidepressant activities.Formule :C15H23NO2SDegré de pureté :98.19%Couleur et forme :SoildMasse moléculaire :281.41Ref: TM-T60027
1mg73,00€5mg146,00€10mg208,00€25mg319,00€50mg447,00€100mg600,00€200mg808,00€1mL*10mM (DMSO)155,00€Apoptosis Compound Library
A unique collection of 1760 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening;Couleur et forme :Odour SolidRef: TM-L9000
1mgÀ demander30μL*10mM (DMSO)À demander50μL*10mM (DMSO)À demander100μL*10mM (DMSO)À demander250μL*10mM (DMSO)À demanderMinesapride
CAS :Minesapride: novel 5-HT4 partial agonist, may treat constipation-predominant IBS.
Formule :C21H31ClN4O5Degré de pureté :99.85% - 99.88%Couleur et forme :SolidMasse moléculaire :454.95Neural Regeneration Compound Library
A unique collection of 149 neuroregeneration related compounds for high throughput and high content screening;Couleur et forme :Odour SolidRef: TM-L7700
1mgÀ demander30μL*10mM (DMSO)À demander50μL*10mM (DMSO)À demander100μL*10mM (DMSO)À demander250μL*10mM (DMSO)À demanderCNS-Penetrant Compound Library
A unique collection of 509 CNS-Penetrant compounds for high throughput screening (HTS) and high content screening (HCS);Couleur et forme :Odour SolidRef: TM-L5900
1mgÀ demander30μL*10mM (DMSO)À demander50μL*10mM (DMSO)À demander100μL*10mM (DMSO)À demander250μL*10mM (DMSO)À demanderCalcium Channel Compound Library
A unique collection of 140 calcium channel blockers and agonists for high throughput and high content screening;Couleur et forme :Odour SolidRef: TM-L7200
1mgÀ demander30μL*10mM (DMSO)À demander50μL*10mM (DMSO)À demander100μL*10mM (DMSO)À demander250μL*10mM (DMSO)À demanderIon Channel Targeted Library
A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;
Couleur et forme :Odour SolidSerotonin Receptor-Targeted Compound Library
A unique collection of xnum compounds targeting serotonin receptors for high throughput screening and high content screening;Couleur et forme :Odour SolidRef: TM-L2800
1mgÀ demander30μL*10mM (DMSO)À demander50μL*10mM (DMSO)À demander100μL*10mM (DMSO)À demander250μL*10mM (DMSO)À demanderNeurotransmitter Receptor Compound Library
A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening；
Couleur et forme :Odour SolidFezolamine
CAS :Fezolamine: a new, non-tricyclic, oral antidepressant, selectively inhibits norepinephrine uptake over serotonin or dopamine.Formule :C20H23N3Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :305.42
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