récepteur 5-HT
Les récepteurs 5-HT, également connus sous le nom de récepteurs de la sérotonine, sont un groupe de récepteurs couplés aux protéines G (GPCR) qui médiatisent les effets de la sérotonine, un neurotransmetteur impliqué dans la régulation de l'humeur, l'anxiété, le sommeil, l'appétit et d'autres processus physiologiques. Ces récepteurs sont divisés en plusieurs sous-types, chacun ayant des fonctions et des propriétés pharmacologiques distinctes. Les modulateurs des récepteurs 5-HT sont largement étudiés pour leurs rôles dans le traitement de la dépression, des troubles anxieux et d'autres affections neuropsychiatriques. Chez CymitQuimica, nous offrons une gamme de modulateurs des récepteurs 5-HT de haute qualité pour soutenir vos recherches en neuropharmacologie, troubles de l'humeur et signalisation GPCR.
1024 produits trouvés pour "récepteur 5-HT"
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(S)-Praziquantel
CAS :(S)-Praziquantel is the inactive isomer of R-praziquantel.Formule :C19H24N2O2Couleur et forme :SolidMasse moléculaire :312.406VA012
CAS :VA012 (compound 11) acts as a positive allosteric modulator (PAM) of the serotonin 5-HT2C receptor. It has been shown to reduce food intake and prevent weight gain during subchronic administration without causing central nervous system-related discomfort. VA012 is applicable in obesity research.Formule :C21H19N3Couleur et forme :SolidMasse moléculaire :313.408 Hydroxy PIPAT oxalate
CAS :8 Hydroxy PIPAT oxalate is a selective 5-HT1A receptor agonist that enhances the spontaneous release of histamine by promoting the degranulation of mast cells in guinea pig and human intestinal preparations. By activating the serotonin signaling pathway, this compound demonstrates potential in regulating gastrointestinal functions and offers insight into the management and suppression of functional gastrointestinal disorders such as irritable bowel syndrome. Its effects in increasing histamine release could play a crucial role in gastrointestinal regulation.Formule :C18H24INO5Couleur et forme :SolidMasse moléculaire :461.295-HT2A/5-HT2C inverse agonist 1
CAS :5-HT2A/5-HT2C inverse agonist 1 serves as a dual and potent inverse agonist for the 5-HT2A and 5-HT2C receptors, with hERG inhibition properties that mitigate cardiovascular risks. Demonstrating significant antipsychotic efficacy in the MK-801-induced mouse model, this compound holds potential for psychosis research.Formule :C24H35N5O2Couleur et forme :SolidMasse moléculaire :425.57Remlifanserin
CAS :Remlifanserin is a potent inverse agonist of the serotonin receptor (5-HT2A).Formule :C24H29F2N3O2Couleur et forme :SolidMasse moléculaire :429.50Avitriptan
CAS :Avitriptan is a 5-HT1B/1D receptor agonist with pKi values of 7.44 for 5-HT1Brat, 7.68 for 5-HT1Bhuman, and 8.36 for 5-HT1Dhuman. It can induce contraction in isolated coronary arteries and is used for the treatment of migraines.Formule :C22H30N6O3SMasse moléculaire :458.577Beloxepin
CAS :Beloxepin is an oral dual selective inhibitor of serotonin and norepinephrine uptake.Formule :C19H21NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :295.385-HT2A receptor agonist-7
CAS :5-HT2A receptor agonist-7 (517) functions as a modulator of the 5-HT2A receptor, with an EC50 value of less than 100 nM.Formule :C12H11F2N3Masse moléculaire :235.23325C-NBF hydrochloride
CAS :25C-NBF hydrochloride is an agonist of 5-HT receptors, specifically activating 5-HT2A and 5-HT2C receptors, with an EC50 of approximately 0.3 μM.Formule :C17H20Cl2FNO2Masse moléculaire :360.251AAZ-A 154 benzoate
CAS :<p>AAZ-A 154 benzoate is a selective, competitive, and non-hallucinogenic 5-HT2AR antagonist. This compound facilitates neuronal growth in rodents and produces lasting beneficial behavioral effects.</p>Formule :C21H26N2O3Couleur et forme :SolidMasse moléculaire :354.44AAZ-A 154 mesylate
CAS :AAZ-A 154 mesylate mesylate is a selective, competitive, and non-hallucinogenic antagonist of 5-HT2AR. It enhances neuronal growth in rodents and produces enduring beneficial behavioral effects.Formule :C15H24N2O4SCouleur et forme :SolidMasse moléculaire :328.43Jimscaline
CAS :Jimscaline (compound R-(-)2) is a 5-HT2A agonist and a mescaline analogue, used in neuroscience research.Formule :C13H19NO3Masse moléculaire :237.295CTW0404
CAS :CTW0404 is an effective positive allosteric modulator (PAM) of the 5-HT receptor, with promising implications for research into neuropsychiatric disorders.Formule :C21H33N3O2Masse moléculaire :359.51SB-224289 hydrochloride
CAS :SB-224289 hydrochloride (SB-224289A) is a selective antagonist of 5-HT1B receptor, with anxiolytic effect.Formule :C32H33ClN4O3Degré de pureté :98.99% - 99.96%Couleur et forme :SolidMasse moléculaire :557.08SB-399885 hydrochloride
CAS :SB-399885 hydrochloride is an antagonist of 5-HT6 receptor.Formule :C18H22Cl3N3O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :482.81Pumosetrag Hydrochloride
CAS :Pumosetrag Hydrochloride is an orally available 5-HT3 partial agonist. It is developed for the treatment of irritable bowel syndrome and gastroesophageal reflux disease.Formule :C15H18ClN3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :339.847-Desmethyl-agomelatine
CAS :7-Desmethyl-agomelatine, a metabolite of Agomelatine, exhibits lower activity than Agomelatine, which functions as a melatonergic (MT1 and MT2) agonist and 5-HT2C antagonist.Formule :C14H15NO2Couleur et forme :SolidMasse moléculaire :229.27Arotinolol
CAS :Arotinolol is a nonselective α/β-adrenergic receptor blocker and a vasodilating β-blocker. Arotinolol also shows potency for inhibiting the binding of the radioligand [125I-ICYP] to [5HT1B-serotonergic] receptor sites. It is an antihypertensive agent.Formule :C15H21N3O2S3Couleur et forme :White SolidMasse moléculaire :371.54BRL 15572
CAS :BRL 15572 is a useful organic compound for research related to life sciences. The catalog number is T64501 and the CAS number is 734517-40-9.Formule :C25H27ClN2OCouleur et forme :SolidMasse moléculaire :406.95Desmethyl cariprazine
CAS :Desmethyl cariprazine is a Cariprazine active metabolite. Cariprazine, an antipsychotic drug candidate, shows a high affinity for the D3 (Ki: 0.085 nM) and D2 (Ki: 0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (2.6 nM).Formule :C20H30Cl2N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :413.38Sarizotan
CAS :Sarizotan (EMD 128130) is an orally active compound that acts as an agonist for serotonin 5-HT 1A receptors and dopamine receptors, with IC50 values of 6.5 nM for rat 5-HT 1A, 0.1 nM for human 5-HT 1A, 15.1 nM for rat D 2, 17 nM for human D 2, 6.8 nM for human D 3, and 2.4 nM for human D 4.2.Formule :C22H21FN2OCouleur et forme :SolidMasse moléculaire :348.421RU 24969 succinate
CAS :<p>RU 24969 succinate, a 5-HT receptor agonist, exhibits K i values of 0.38 nM for 5-HT 1B and 2.5 nM for 5-HT 1A, indicating its affinity towards these receptors. It reduces fluid consumption and enhances forward locomotion. This compound is utilized in neurological disease research.</p>Formule :C18H22N2O5Couleur et forme :SolidMasse moléculaire :346.382-Methyl-5-HT hydrochloride
CAS :2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.Formule :C11H15ClN2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :226.7Flumexadol
CAS :Flumexadol is a selective 5-HT2C receptor agonist with an affinity (Ki) of 25 nM for the (+)-enantiomer and exhibits 40-fold selectivity over the 5-HT2A receptor. It is an orally active, non-narcotic analgesic.Formule :C11H12F3NODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :231.21
