récepteur 5-HT
Les récepteurs 5-HT, également connus sous le nom de récepteurs de la sérotonine, sont un groupe de récepteurs couplés aux protéines G (GPCR) qui médiatisent les effets de la sérotonine, un neurotransmetteur impliqué dans la régulation de l'humeur, l'anxiété, le sommeil, l'appétit et d'autres processus physiologiques. Ces récepteurs sont divisés en plusieurs sous-types, chacun ayant des fonctions et des propriétés pharmacologiques distinctes. Les modulateurs des récepteurs 5-HT sont largement étudiés pour leurs rôles dans le traitement de la dépression, des troubles anxieux et d'autres affections neuropsychiatriques. Chez CymitQuimica, nous offrons une gamme de modulateurs des récepteurs 5-HT de haute qualité pour soutenir vos recherches en neuropharmacologie, troubles de l'humeur et signalisation GPCR.
1025 produits trouvés pour "récepteur 5-HT"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
Flopropione
CAS :Flopropione (Phloropropiophenone), a spasmolytic or antispasmodic agent, is used as a 5-HT1A receptor antagonist.Formule :C9H10O4Degré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :182.17Levodropropizine
CAS :Levodropropizine ((S)-(-)-Dropropizine) is a histamine receptor inhibitor. It is used as an effective and very well tolerated peripheral antitussive drug.Formule :C13H20N2O2Degré de pureté :99.87% - 99.93%Couleur et forme :White Or Off White Crystalline PowderMasse moléculaire :236.31Alverine citrate
CAS :Alverine citrate (NSC 35459) is utilized in functional gastrointestinal disorders.Formule :C26H35NO7Degré de pureté :98.53% - 99.43%Couleur et forme :CoaMasse moléculaire :473.57Lintopride HCl
CAS :Lintopride HCl is a 5HT-4 antagonist.Formule :C14H20Cl2N4O2Degré de pureté :98.42% - 98.81%Couleur et forme :SoildMasse moléculaire :347.24Citalopram hydrobromide
CAS :Citalopram hydrobromide (XU-62-320) , a selective serotonin reuptake inhibitor (SSRI), selectively inhibits the CNS neuronal reuptake of serotonin, therebyFormule :C20H22BrFN2ODegré de pureté :99.81%Couleur et forme :White Crystalline PowderMasse moléculaire :405.304BF-1
CAS :BF-1 blocks 5-HT2B, may prevent migraines by hindering BW723C86/mCPP in guinea pigs.Formule :C22H25NO2SDegré de pureté :>99.99% - >99.99%Couleur et forme :SolidMasse moléculaire :367.50Amisulpride
CAS :Amisulpride (Solian/Deniban), a dopamine antagonist antipsychotic, treats psychosis and schizophrenia in Europe/Australia, not in the US.Formule :C17H27N3O4SDegré de pureté :99.97% - 99.99%Couleur et forme :White Or Almost White Crystalline PowderMasse moléculaire :369.48Carvedilol EP IMpurity E
CAS :Carvedilol EP IMpurity E (Carvedilol USP E) is used as a pharmaceutical intermediate.Formule :C9H14ClNO2Degré de pureté :99.53%Couleur et forme :White To Almost White Solid CrystallineMasse moléculaire :203.666Tropanserin
CAS :Tropanserin (MDL 72422) is a 5-hydroxytryptamine receptor antagonist with anxiolytic activity that is used to treat depression and cognitive impairment.Formule :C17H23NO2Degré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :273.37Cloperastine hydrochloride
CAS :Cloperastine hydrochloride (HT-11 hydrochloride) is a type of flavonoid.Formule :C20H25Cl2NODegré de pureté :97.74% - 99.42%Couleur et forme :SolidMasse moléculaire :366.33Fluoxetine
CAS :Fluoxetine (LY-110140), a specific serotonin inhibitor, serves as an antidepressant with fewer side-effects.Formule :C17H18F3NODegré de pureté :99.07% - 99.28%Couleur et forme :SolidMasse moléculaire :309.33Quetiapine
CAS :Quetiapine treats schizophrenia and bipolar I, targeting serotonin, dopamine, and adrenoreceptor subtypes, plus H1 histamine receptor.Formule :C21H25N3O2SDegré de pureté :99.14% - 99.63%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :383.51Cloroperone
CAS :Cloroperone has anxiolytic activity and may be used in the study of neurologic disorders.Formule :C22H23ClFNO2Degré de pureté :98.40%Couleur et forme :SoildMasse moléculaire :387.88Fluoxetine hydrochloride
CAS :Fluoxetine HCl (Lilly110140), a selective serotonin reuptake inhibitor (SSRI), is an antidepressant with fewer side effects.Formule :C17H19ClF3NODegré de pureté :99.6% - 99.98%Couleur et forme :White To Off-White Crystalline Solid White To Off-White PowderMasse moléculaire :345.787Zolmitriptan
CAS :Zolmitriptan targets 5-HT 1B/1D receptors, constricts cranial vessels, inhibits pain signals, and stops pro-inflammatory neuropeptides, alleviating migraines.Formule :C16H21N3O2Degré de pureté :99.69% - 99.91%Couleur et forme :White Or Kind Of White PowderMasse moléculaire :287.36Frovatriptan succinate hydrate
CAS :Frovatriptan treats all migraine types, nausea, vomiting, light/sound sensitivity, and prevents menstrual migraines; it targets 5-HT1B/D and 5-HT7 receptors.Formule :C18H25N3O6Degré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :379.41Cisapride
CAS :Cisapride (R 51619), a 5-HT4 agonist, enhances gut peristalsis and gastric emptying, reduces reflux.Formule :C23H29ClFN3O4Degré de pureté :99.77%Couleur et forme :White To Slightly Biege Powder SolidMasse moléculaire :465.95Ref: TM-T1291
5mg44,00€10mg56,00€25mg73,00€50mg94,00€100mg128,00€200mg222,00€500mg374,00€1mL*10mM (DMSO)52,00€Blonanserin
CAS :Blonanserin (AD-5423), approved in Japan (2008), is an atypical antipsychotic with fewer side effects like EPS, sedation, or hypotension.Formule :C23H30FN3Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :367.50Protriptyline hydrochloride
CAS :Protriptyline HCl: a tricyclic antidepressant that increases norepinephrine and serotonin levels and has anticholinergic effects.Formule :C19H21N·HClDegré de pureté :98.54% - 99.98%Couleur et forme :SolidMasse moléculaire :299.84Olanzapine
CAS :Olanzapine (LY170053) is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness.Formule :C17H20N4SDegré de pureté :99.86% - ≥95%Couleur et forme :Yellowish Crystalline PowderMasse moléculaire :312.43Ketanserin
CAS :Ketanserin: quinazoline derivative, 5-HT2 receptor antagonist, may lower blood pressure and inhibit blood clots.Formule :C22H22FN3O3Degré de pureté :99.19% - 99.73%Couleur et forme :SolidMasse moléculaire :395.43Agomelatine
CAS :Agomelatine (Valdoxan), like melatonin, boosts mood by targeting melatonin and 5-HT2C receptors.Formule :C15H17NO2Degré de pureté :99.92%Couleur et forme :White SolidMasse moléculaire :243.30Ref: TM-T1445
2mgÀ demander5mg49,00€10mg63,00€25mg105,00€50mg170,00€100mg236,00€1mL*10mM (DMSO)50,00€Azatadine dimaleate
CAS :Azatadine dimaleate (SCH10649) is an inhibitor for histamine（IC50=6.5 nM） and cholinergic（IC50=10 nM）.
Formule :C28H30N2O8Degré de pureté :99.7% - >99.99%Couleur et forme :PowderMasse moléculaire :522.55RS102895 hydrochloride
CAS :RS102895 hydrochloride is a potent antagonist of CCR2(IC50 of 360 nM).Formule :C21H22ClF3N2O2Degré de pureté :98.95%Couleur et forme :SolidMasse moléculaire :426.86Gevotroline
CAS :Gevotroline, a chemical in palm wine that can be used to treat psychosis, is a 5-HT2 receptor antagonist that can be used to study behavioral disorders.Formule :C19H20FN3Degré de pureté :99.45%Couleur et forme :SolidMasse moléculaire :309.38ECPLA
CAS :ECPLA is an LSD analog and a potent 5-HT2A agonist (EC50 of 14.6 nM), capable of stimulating Gq-mediated calcium flux. It exhibits high affinity for most serotonin receptors, α2-adrenergic receptors, and D2-like dopamine receptors.Formule :C21H25N3OCouleur et forme :SolidMasse moléculaire :335.44SB 216641
CAS :SB 216641 is a 5-HT (1B/1D) antagonist with anxiolytic activity for the study of anxiety disorders and depression.Formule :C28H30N4O4Degré de pureté :98.09%Couleur et forme :SolidMasse moléculaire :486.56(+)-OSU 6162
CAS :(+)-OSU 6162 (Piperidine, 3-[3-(methylsulfonyl)phenyl]-1-propyl-, (3R)-) is an agonist of 5-HT Receptor with anti-Alzheimer and antidepressant activities.Formule :C15H23NO2SDegré de pureté :98.19%Couleur et forme :SoildMasse moléculaire :281.41Ref: TM-T60027
1mg73,00€5mg146,00€10mg208,00€25mg319,00€50mg447,00€100mg600,00€200mg808,00€1mL*10mM (DMSO)155,00€MR33317
MR33317 is an inhibitor of acetylcholinesterase with an IC50 value of 41 nM. Additionally, it acts as an agonist for brain 5-HT4 receptors.Formule :C22H28ClN3O2Masse moléculaire :401.187Minesapride
CAS :Minesapride: novel 5-HT4 partial agonist, may treat constipation-predominant IBS.
Formule :C21H31ClN4O5Degré de pureté :99.85% - 99.88%Couleur et forme :SolidMasse moléculaire :454.95Cinanserin hydrochloride
CAS :Cinanserin hydrochloride (SQ 10643) is a 5-HT2 receptor blocker (Ki: 41 nM) and SARS-CoV 3C-like protease inhibitor.Formule :C20H25ClN2OSDegré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :376.94Neocarzinostatin
CAS :Neocarzinostatin is an effective DNA-damaging, anti-tumor antibiotic.Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :N/AIloperidone metabolite P95
CAS :Iloperidone metabolite P95, a non-brain penetrating compound, binds 5-HT2A, α1-, α2B-, α2C-receptors with Ki of 7.08-83.18 nM.Formule :C23H25FN2O5Couleur et forme :SolidMasse moléculaire :428.465-HT2C agonist-4
CAS :Compound 3i, a 5-HT2C agonist-4, acts as an agonist for the 5-HT2C receptor with an EC50 of 5.7 nM. It is capable of reducing locomotor activity in zebrafish larvae.Formule :C24H25N5OCouleur et forme :SolidMasse moléculaire :399.495-HT6 inverse agonist 1
CAS :5-HT6 inverse agonist 1 (Compound 33) is an antagonist of the 5-HT6 receptor with a Ki of 23 nM and a Kb of 6.62 nM. This compound can inhibit 5-HT6R-mediated Cdk5 and mTOR signaling pathways and reduce tactile allodynia induced by spinal nerve ligation (SNL) in rat models.Formule :C22H22Cl2FN3O3SCouleur et forme :SolidMasse moléculaire :498.4ALEPH hydrochloride
CAS :ALEPH (hydrochloride) acts as a partial agonist of h5-HT2A and h5-HT2B receptors, with EC50 values of 10.3 nM and 19.2 nM, respectively. It can induce head twitch responses in mice, with an ED50 of 0.80 mg/kg.Formule :C12H20ClNO2SCouleur et forme :SolidMasse moléculaire :277.81Donitriptan hydrochloride
CAS :Donitriptan hydrochloride (Donitriptan monohydrochloride) is a potent, high efficacy agonist of 5-HT1B/1D receptors with pKis of 9.4 and 9.3, respectivelyFormule :C23H26ClN5O2Degré de pureté :99.8% - 99.86%Couleur et forme :SolidMasse moléculaire :439.94Ref: TM-T21666
2mg40,00€5mg49,00€10mg64,00€25mg135,00€50mg240,00€100mg339,00€200mg439,00€500mgÀ demanderSB 699551
CAS :SB 699551 is a selective 5-HT5A antagonist (Ki=6.31 nM) that enhances 5-HT neuronal function. It inhibits SERT (Ki=25.12 nM),inhibit breast cancer.Formule :C34H45N3ODegré de pureté :99.83%Couleur et forme :SoildMasse moléculaire :511.74Ref: TM-T23325L
1mg190,00€5mg471,00€10mg662,00€25mg1.036,00€50mg1.429,00€100mg1.821,00€200mg2.489,00€PSEM 308 hydrochloride
PSAM agonist targeting PSAML141F-GlyR and related ion channels in mice; ideal concentration ≤5 mg/kg; plasmids at Addgene.Couleur et forme :Solidmeta-Fluoxetine (hydrochloride)
CAS :meta-Fluoxetine (hydrochloride) can be used in related research in the field of life sciences. Its product number is T37474 and CAS number is 79088-29-2.Formule :C17H19ClF3NOCouleur et forme :SolidMasse moléculaire :345.79Lisuride maleate
CAS :Lisuride maleate is a non-selective dopamine agonist and G-protein-biased 5-HT2A receptor agonist capable of blocking prolactin release.Formule :C24H30N4O5Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :454.52Ref: TM-T8775
1mg204,00€5mg627,00€10mg898,00€25mg1.346,00€50mg1.745,00€100mg2.382,00€1mL*10mM (DMSO)627,00€Asenapine citrate
CAS :Asenapine citrate: atypical antipsychotic for schizophrenia, bipolar disorder; targets serotonin, adrenoceptors, dopamine, histamine (pKi: 8.2-10.5).Formule :C23H24ClNO8Couleur et forme :SolidMasse moléculaire :477.89(R,R)-Palonosetron Hydrochloride
CAS :(R,R)-Palonosetron Hydrochloride is the active enantiomer of PalonosetronFormule :C19H25ClN2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :332.875-MeO-pyr-T
CAS :5-MeO-pyr-T (5-Methoxy pyrrolidinyltryptamine) acts as a 5-HT1AR agonist, exhibiting Ki values of 0.577 μM and 373 μM for 5-HT1AR and 5-HT2AR, respectively. It inhibits the reuptake of 5-HT and triggers its release. Additionally, 5-MeO-pyr-T can induce reduced motor activity.Formule :C15H20N2OCouleur et forme :SolidMasse moléculaire :244.335-HT1AR/5-HT6R ligand-1
5-HT1AR/5-HT6R ligand-1 (Compound PP13) functions as a ligand for the 5-HT receptor, demonstrating high affinity for 5-HT1AR, 5-HT6R, and 5-HT7R with Ki values of 19, 69, and 198 nM, respectively. In HEK293 cells, it inhibits cAMP production with EC50 values of 1535, 488, and 53 nM for these receptors. Additionally, 5-HT1AR/5-HT6R ligand-1 exhibits antiproliferative effects on several cancer cell lines, including 1321N1, U87MG, MCF7, and AsPC-1, with IC50 values of 9.6, 13.6, 19.3, and 14.6 μM, respectively. The compound also shows antagonistic activity towards the dopamine receptor D2R, with a Ki of 1903 nM.Formule :C25H29ClN4O2SCouleur et forme :SolidMasse moléculaire :485.045-HT6R antagonist 6
5-HT6R antagonist 6 (Compound PP15) exhibits high affinity and selectivity for the 5-HT6R receptor, with a Ki of 42 nM. It demonstrates weak antiproliferative activity on tumor cells and low toxicity toward normal cells. 5-HT6R antagonist 6 is applicable in tumor research.Formule :C24H26N4O2SCouleur et forme :SolidMasse moléculaire :434.55(-)-Eseroline fumarate
CAS :(-)-Eseroline fumarate, a Physostigmine metabolite and AChE inhibitor, triggers cancer cell LDH release and neuronal cell death.Formule :C17H22N2O5Couleur et forme :SolidMasse moléculaire :334.37Paynantheine
CAS :Paynantheine is an alkaloid with antinociceptive properties, found in Mitragyna speciosa. It also acts as an agonist at 5-HT1AR and 5-HT2BR receptors, inducing lower lip contraction and providing antinociception in rats.Formule :C23H28N2O4Couleur et forme :SolidMasse moléculaire :396.48LY 344864 racemate
CAS :LY 344864 racemate is a 5-HT1F receptor agonist.Formule :C21H22FN3ODegré de pureté :99.75%Couleur et forme :SoildMasse moléculaire :351.42Imipramine N-oxide
CAS :Imipramine N-oxide is a tricyclic antidepressant (TCA) and imipramine analogue used to treat depression.Formule :C19H24N2ODegré de pureté :99.80%Couleur et forme :SolidMasse moléculaire :296.41Ref: TM-T74205
1mg72,00€5mg157,00€10mg241,00€25mg409,00€50mg565,00€100mg794,00€1mL*10mM (DMSO)167,00€
