récepteur 5-HT
Les récepteurs 5-HT, également connus sous le nom de récepteurs de la sérotonine, sont un groupe de récepteurs couplés aux protéines G (GPCR) qui médiatisent les effets de la sérotonine, un neurotransmetteur impliqué dans la régulation de l'humeur, l'anxiété, le sommeil, l'appétit et d'autres processus physiologiques. Ces récepteurs sont divisés en plusieurs sous-types, chacun ayant des fonctions et des propriétés pharmacologiques distinctes. Les modulateurs des récepteurs 5-HT sont largement étudiés pour leurs rôles dans le traitement de la dépression, des troubles anxieux et d'autres affections neuropsychiatriques. Chez CymitQuimica, nous offrons une gamme de modulateurs des récepteurs 5-HT de haute qualité pour soutenir vos recherches en neuropharmacologie, troubles de l'humeur et signalisation GPCR.
940 produits trouvés pour "récepteur 5-HT"
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AAZ-A 154 benzoate
CAS :<p>AAZ-A 154 benzoate is a selective, competitive, and non-hallucinogenic 5-HT2AR antagonist. This compound facilitates neuronal growth in rodents and produces lasting beneficial behavioral effects.</p>Formule :C21H26N2O3Couleur et forme :SolidMasse moléculaire :354.44F 14679
CAS :<p>F 14679 is a potent 5-HT1A agonist (pKi=10.23) with a maximum Ca2t response similar to 5-HT.</p>Formule :C21H25ClF2N4ODegré de pureté :99.09%Couleur et forme :SolidMasse moléculaire :422.9AAZ-A 154 mesylate
CAS :<p>AAZ-A 154 mesylate mesylate is a selective, competitive, and non-hallucinogenic antagonist of 5-HT2AR. It enhances neuronal growth in rodents and produces enduring beneficial behavioral effects.</p>Formule :C15H24N2O4SCouleur et forme :SolidMasse moléculaire :328.438 Hydroxy PIPAT oxalate
CAS :<p>8 Hydroxy PIPAT oxalate is a selective 5-HT1A receptor agonist that enhances the spontaneous release of histamine by promoting the degranulation of mast cells in guinea pig and human intestinal preparations. By activating the serotonin signaling pathway, this compound demonstrates potential in regulating gastrointestinal functions and offers insight into the management and suppression of functional gastrointestinal disorders such as irritable bowel syndrome. Its effects in increasing histamine release could play a crucial role in gastrointestinal regulation.</p>Formule :C18H24INO5Couleur et forme :SolidMasse moléculaire :461.29Beloxepin
CAS :<p>Beloxepin is an oral dual selective inhibitor of serotonin and norepinephrine uptake.</p>Formule :C19H21NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :295.38(-)-5-HT2C agonist-3
CAS :<p>Compound (−)-19, also known as (-)-5-HT2C agonist-3, is a selective 5-HT2C agonist exhibiting a preference for Gq signaling. It demonstrates efficiency with EC50 values for 5-HT2 receptor subtypes as follows: 5-HT2C at 103 nM, 5-HT2B at 570 nM, and 5-HT2A at 72 nM. This compound is utilized in research on antipsychotics.</p>Formule :C19H23ClFNO2Couleur et forme :SolidMasse moléculaire :351.84AAZ-A 154 hydrochloride
CAS :<p>AAZ-A 154 hydrochloride is a selective, competitive, non-hallucinogenic antagonist of 5-HT2AR. It promotes neuronal growth in rodents and results in enduring beneficial behavioral effects.</p>Formule :C14H21ClN2OCouleur et forme :SolidMasse moléculaire :268.78YM-31636 free base
CAS :<p>YM-31636 (free base) is an orally active, potent, and selective agonist of the 5-HT3 receptor with a pKi value of 9.67. This compound induces contraction in isolated guinea pig distal colon and provokes tachycardia in isolated guinea pig right atrium, demonstrating a relative intrinsic activity of about 0.23. YM-31636 (free base) holds potential for research in constipation management.</p>Formule :C14H11N3SCouleur et forme :SolidMasse moléculaire :253.32SB-224289 hydrochloride
CAS :<p>SB-224289 hydrochloride (SB-224289A) is a selective antagonist of 5-HT1B receptor, with anxiolytic effect.</p>Formule :C32H33ClN4O3Degré de pureté :97.82% - 98.99%Couleur et forme :SolidMasse moléculaire :557.08Pumosetrag Hydrochloride
CAS :<p>Pumosetrag Hydrochloride is an orally available 5-HT3 partial agonist. It is developed for the treatment of irritable bowel syndrome and gastroesophageal reflux disease.</p>Formule :C15H18ClN3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :339.84SB-399885 hydrochloride
CAS :<p>SB-399885 hydrochloride is an antagonist of 5-HT6 receptor.</p>Formule :C18H22Cl3N3O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :482.817-Desmethyl-agomelatine
CAS :<p>7-Desmethyl-agomelatine, a metabolite of Agomelatine, exhibits lower activity than Agomelatine, which functions as a melatonergic (MT1 and MT2) agonist and 5-HT2C antagonist.</p>Formule :C14H15NO2Couleur et forme :SolidMasse moléculaire :229.27Arotinolol
CAS :<p>Arotinolol is a nonselective α/β-adrenergic receptor blocker and a vasodilating β-blocker. Arotinolol also shows potency for inhibiting the binding of the radioligand [125I-ICYP] to [5HT1B-serotonergic] receptor sites. It is an antihypertensive agent.</p>Formule :C15H21N3O2S3Couleur et forme :White SolidMasse moléculaire :371.54BRL 15572
CAS :<p>BRL 15572 is a useful organic compound for research related to life sciences. The catalog number is T64501 and the CAS number is 734517-40-9.</p>Formule :C25H27ClN2OCouleur et forme :SolidMasse moléculaire :406.95Sarizotan
CAS :<p>Sarizotan (EMD 128130) is an orally active compound that acts as an agonist for serotonin 5-HT 1A receptors and dopamine receptors, with IC50 values of 6.5 nM for rat 5-HT 1A, 0.1 nM for human 5-HT 1A, 15.1 nM for rat D 2, 17 nM for human D 2, 6.8 nM for human D 3, and 2.4 nM for human D 4.2.</p>Formule :C22H21FN2OCouleur et forme :SolidMasse moléculaire :348.421Desmethyl cariprazine
CAS :<p>Desmethyl cariprazine is a Cariprazine active metabolite. Cariprazine, an antipsychotic drug candidate, shows a high affinity for the D3 (Ki: 0.085 nM) and D2 (Ki: 0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (2.6 nM).</p>Formule :C20H30Cl2N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :413.38(Rac)-Rotigotine hydrochloride
CAS :<p>(Rac)-Rotigotine hydrochloride is a racemate of Rotigotine. Rotigotine is a full agonist of dopamine receptor, a partial the 5-HT1A receptor agonist.</p>Formule :C19H26ClNOSCouleur et forme :SolidMasse moléculaire :351.93NLX-204 hydrochloride(2170405-10-2 free base)
<p>NLX-204 hydrochloride is a potent and selective ERK1/2 phosphorylation-preferring serotonin 5 HT1A receptor agonist(pKi = 10.19).</p>Formule :C20H23Cl2F2N3O2Degré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :446.322-Methyl-5-HT hydrochloride
CAS :<p>2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.</p>Formule :C11H15ClN2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :226.7Flumexadol
CAS :<p>Flumexadol is a selective 5-HT2C receptor agonist with an affinity (Ki) of 25 nM for the (+)-enantiomer and exhibits 40-fold selectivity over the 5-HT2A receptor. It is an orally active, non-narcotic analgesic.</p>Formule :C11H12F3NODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :231.21
