ATP Citrate Lyase
Les inhibiteurs de l'ATP citrate lyase sont des composés qui ciblent l'enzyme ATP citrate lyase, jouant un rôle clé dans la biosynthèse des acides gras et du cholestérol en convertissant le citrate en acétyl-CoA. Dans le contexte des neurosciences, ces inhibiteurs suscitent un intérêt en raison de leurs effets potentiels sur le métabolisme des lipides dans le cerveau, crucial pour le maintien de la fonction et de l'intégrité neuronales. L'inhibition de l'ATP citrate lyase peut avoir des implications pour les maladies neurodégénératives, où le métabolisme des lipides est souvent dysrégulé. Chez CymitQuimica, nous proposons des inhibiteurs de l'ATP citrate lyase pour soutenir vos recherches sur le métabolisme cérébral, la neurodégénérescence et le développement thérapeutique.
17 produits trouvés pour "ATP Citrate Lyase"
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(-)-Hydroxycitric acid
CAS :(-)-Hydroxycitric acid from Garcinia cambogia rinds inhibits ATP citrate lyase, reducing fat synthesis and aiding weight loss.Formule :C6H8O8Degré de pureté :99.77% - 99.90%Couleur et forme :SolidMasse moléculaire :208.12(-)-Hydroxycitric acid lactone
CAS :(-)-Hydroxycitric acid lactone (Garcinia lactone) is an anti-obesity agent.(-)-Hydroxycitric acid lactone was a potent inhibitor of ATP citrate lyase, whichFormule :C6H6O7Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :190.11Citric acid trilithium salt tetrahydrate
CAS :Citric acid trilithium salt tetrahydrate (Lithium citrate tribasic tetrahydrate) , the active component of Lithium, is a medicine used in the therapy ofFormule :C6H13Li3O11Degré de pureté :99.88%Couleur et forme :White Crystalline PowderMasse moléculaire :281.98Hydroxycitric acid tripotassium hydrate
CAS :Hydroxycitric acid tripotassium hydrate (Potassium citrate monohydrate) effectively inhibits HIF, has antioxidation, anti-inflammation, and anti-tumor effects.Formule :C6H7K3O8Degré de pureté :99.85%Couleur et forme :White Solid CrystallineMasse moléculaire :324.41Forrestiacids J
CAS :Forrestiacid J is an inhibitor of ATP-citrate lyase (ACL), exhibiting an IC50 value of 2.6 μM [1].Formule :C50H74O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :771.12Forrestiacids K
CAS :Forrestiacid K, a terpenoid derived from Pseudotsuga forrestii, functions as an inhibitor of ATP-citrate lyase (ACL) [1].Formule :C50H74O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :771.12ATP citrate lyase/ACLY Protein, Human, Recombinant (His)
ATP citrate lyase, also known as Acly or Acl, is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues.Degré de pureté :96%Couleur et forme :Lyophilized PowderMasse moléculaire :123 kDa (predicted); 110 kDa (reducing conditions)Ref: TM-TMPY-02483
5µg89,00€10µg126,00€20µg202,00€50µg397,00€100µg669,00€200µg1.134,00€500µg2.225,00€Anti-ATP citrate lyase/ACLY Antibody (9F685)
Anti-ATP citrate lyase/ACLY Antibody (9F685) is an antibody targeting ATP citrate lyase/ACLY. Anti-ATP citrate lyase/ACLY Antibody (9F685) can be used in ELISA, WB, IF, FCM.Couleur et forme :Odour LiquidSB 204990
CAS :SB 204990 is a lactone prodrug of SB-201076, a potent and specific ATP citrate lyase inhibitor.Cost-effective and quality-assured.Formule :C18H22Cl2O5Degré de pureté :96.32% - 99.6%Couleur et forme :SolidMasse moléculaire :389.27Bempedoic acid
CAS :Bempedoic acid (ETC1002) is an orally available, once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C.Formule :C19H36O5Degré de pureté :99.85% - 99.94%Couleur et forme :SolidMasse moléculaire :344.49Ref: TM-T3625
2mg35,00€5mg52,00€10mg73,00€25mg125,00€50mg217,00€100mg350,00€500mg840,00€1mL*10mM (DMSO)55,00€BMS-303141
CAS :BMS-303141 is a potent ATP-citrate lyase (ACL) inhibitor (IC50: 0.13 uM, human recombinant ACL).Formule :C19H15Cl2NO4SDegré de pureté :98% - 99.47%Couleur et forme :SolidMasse moléculaire :424.3Ref: TM-T2337
1mg35,00€2mg47,00€5mg66,00€10mg87,00€25mg140,00€50mg268,00€100mg393,00€1mL*10mM (DMSO)69,00€NDI-091143
CAS :NDI-091143 is a potent and high-affinity human ATP-citrate lyase (ACLY) inhibitor with an IC50 of 2.1 nM (ADP-Glo assay),indirectly disrupting citrate bindingFormule :C20H14ClF2NO5SDegré de pureté :97.03% - ≥95%Couleur et forme :SolidMasse moléculaire :453.842-Furoic acid
CAS :2-Furoic acid: oral cathepsin K inhibitor, potential for treating osteoporosis and antibacterial.Formule :C5H4O3Degré de pureté :99.53% - 99.65%Couleur et forme :SolidMasse moléculaire :112.08MEDICA16
CAS :MEDICA16: GPR40 agonist, GPR120 partial agonist, ATP-citrate lyase inhibitor, lowers TG, boosts insulin sensitivity in muscle.Formule :C20H38O4Degré de pureté :99.62% - 99.87%Couleur et forme :White SolidMasse moléculaire :342.51Ref: TM-T22967
5mg60,00€10mg92,00€25mg168,00€50mg289,00€100mg419,00€500mg874,00€1mL*10mM (DMSO)80,00€EVT0185
CAS :EVT0185 is an orally active ATP citrate lyase (ACLY) inhibitor. In the liver, it is converted by SLC27A2 into a CoA thioester, which interacts with the CoA binding site of ACLY. EVT0185-CoA inhibits ACLY activity with an IC50 of 2.5 μM. It mimics the immune and antitumor effects seen with ACLY gene deletion. Additionally, EVT0185 elevates levels of tumor-infiltrating B cells and the chemokine CXCL13. It is applicable in cancer research, including hepatocellular carcinoma (HCC).Formule :C22H34O4Couleur et forme :SolidMasse moléculaire :362.50ACLY Inhibitor 7
CAS :ACLY Inhibitor 7 is a potent, selective hACLY inhibitor (IC50<1 nM) for metabolic disease and oncology research.Formule :C21H14ClF2NO6SDegré de pureté :99.74%Couleur et forme :SoildMasse moléculaire :481.85ACLY-IN-1
CAS :ACLY-IN-1 (compound 55) is a potent ACLY inhibitor with an IC50 of 8.3 nM, and it can be utilized in hyperlipidemia research.Formule :C20H12BrClF2N2O4SCouleur et forme :SolidMasse moléculaire :529.74
