Bêta-amyloïde
Les inhibiteurs de bêta-amyloïde sont des composés qui ciblent spécifiquement et inhibent la formation ou l'agrégation des peptides bêta-amyloïdes, impliqués de manière critique dans la pathogenèse de la maladie d'Alzheimer. L'accumulation de plaques bêta-amyloïdes dans le cerveau est l'un des principaux signes pathologiques de la maladie d'Alzheimer, contribuant à la dysfonction neuronale, à la perte synaptique et au déclin cognitif. En empêchant l'agrégation des bêta-amyloïdes, ces inhibiteurs font l'objet de recherches intensives comme agents thérapeutiques potentiels visant à ralentir ou même arrêter la progression de la maladie d'Alzheimer. Chez CymitQuimica, nous proposons une variété d'inhibiteurs de bêta-amyloïde de haute qualité pour soutenir vos recherches sur les troubles neurodégénératifs, l'agrégation des protéines et le développement de thérapies pour la maladie d'Alzheimer.
205 produits trouvés pour "Bêta-amyloïde"
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LY 2389575 hydrochloride
CAS :<p>LY2389575 hydrochloride is a selective mGlu3 NAM with 190 nM IC50, increases Mrc1, and aids Alzheimer's research.</p>Formule :C15H16BrCl3N4Degré de pureté :99.45%Couleur et forme :SolidMasse moléculaire :438.58ALZ-801
CAS :<p>ALZ-801, an oral valine-prodrug of tramiprosate, enhances treatment of Alzheimer's by inhibiting β-amyloid aggregation with better PK and tolerance.</p>Formule :C8H18N2O4SDegré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :238.3Donanemab
CAS :<p>Donanemab (LY3002813), a humanized IgG1 antibody, targets N-terminal Aβ for potential early Alzheimer's research.</p>Degré de pureté :95%Couleur et forme :LiquidGantenerumab
CAS :<p>Gantenerumab (R-1450) is a humanized antibody targeting amyloid-β (Aβ), used in studies of Alzheimer's disease.</p>Degré de pureté :>95%Couleur et forme :LiquidGlimepiride
CAS :<p>Glimepiride (HOE-490) is a long-acting, third-generation sulfonylurea with hypoglycemic activity.</p>Formule :C24H34N4O5SDegré de pureté :97.84% - 98.87%Couleur et forme :White Cyrstalline SolidMasse moléculaire :490.62Cromolyn sodium
CAS :<p>Cromolyn sodium (FPL-670) is a chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells.</p>Formule :C23H14Na2O11Degré de pureté :99.4% - 99.95%Couleur et forme :Colorless Crystals From Ethanol + Ether White Crystalline PowderMasse moléculaire :512.33Lecanemab
CAS :<p>Lecanemab (BAN-2401) is an IgG1 monoclonal antibody targeting soluble aggregated beta amyloid (Abeta) for the study of cognitive disorders.</p>Degré de pureté :95% - 97.3% (SEC-HPLC)Couleur et forme :LiquidChlorzoxazone
CAS :<p>Chlorzoxazone (Chlorzoxazon) is a Muscle Relaxant. The physiologic effect of chlorzoxazone is by means of Centrally-mediated Muscle Relaxation.</p>Formule :C7H4ClNO2Degré de pureté :99.49% - 99.6%Couleur et forme :SolidMasse moléculaire :169.57Eprodisate disodium
CAS :<p>Eprodisate disodium (NC-503) is a negatively charged sulfonated inhibitor of fibrillogenesis, that can be used in the treatment of amyloid A (AA) amyloidosis.</p>Formule :C3H6Na2O6S2Degré de pureté :99.88%Couleur et forme :White Coarse PowderMasse moléculaire :248.19Birtamimab
CAS :<p>Birtamimab (NEOD001) is a monoclonal antibody selectively targeting and depleting amyloid protein, used in research on light chain amyloidosis.</p>Degré de pureté :>95%Couleur et forme :Liquid(Gln22)-Amyloid β-Protein (1-42)
CAS :<p>(Gln22)-Amyloid β-Protein (1-42), a Dutch mutation (E22Q) variant of β-Amyloid (1-42), demonstrates increased fibrillogenic and pathogenic characteristics [1].</p>Formule :C203H312N56O59SCouleur et forme :SolidMasse moléculaire :4513.05β-Amyloid (1-34)
CAS :<p>This is a fragment of beta-amyloid peptide. It has amino acids 1 through 34.</p>Formule :C170H253N47O52Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3787.2Trontinemab
CAS :<p>Trontinemab, a bispecific humanized IgG1-κ antibody, targets the amyloid beta A4 precursor protein (APP) and transferrin receptor p90, CD71 (TFRC).</p>Degré de pureté :96.77% - 99%Couleur et forme :LiquidAβ-IN-7
<p>Aβ-IN-7 (compound 5a) acts as a potent inhibitor of Aβ aggregation, stabilizing Aβ monomers at 50 μM concentration to prevent them from forming larger oligomers</p>Formule :C14H10N2SCouleur et forme :SolidMasse moléculaire :238.31BSBM6
CAS :<p>BSBM6 is an inhibitor of Aβ aggregation and neuronal toxicity that acts by reversing the aggregation and toxicity of amyloid-β peptides.</p>Formule :C23H29N3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :427.49β-Amyloid (35-42)
CAS :<p>β-Amyloid (35-42) is a peptide derived from the beta-amyloid protein, encompassing amino acids 35 through 42.</p>Formule :C33H60N8O9SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :744.94β-Amyloid (1-40)
CAS :<p>Amyloid β1-40 is one of the fragments generated after cleavage of the amyloid peptide precursor protein by β and γ secretases.</p>Formule :C194H295N53O58SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :4329.82β-Amyloid (12-20)
CAS :<p>β-Amyloid (12-20) is a peptide fragment of β-Amyloid.Thsis peptide contain the amino acid residues VFF at position (18-20), suggesting that this triad has</p>Formule :C57H83N15O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1154.36Amyloid β Peptide (42-1)(human) acetate
<p>Amyloid β Peptide (42-1)(human) acetate is the inactive form of Amyloid β Peptide (1-42).</p>Degré de pureté :95.20%Couleur et forme :Soildβ-Amyloid (35-25)
CAS :<p>β-Amyloid (35-25) is the reverse sequence of β-Amyloid (25-35).</p>Formule :C45H81N13O14SMasse moléculaire :1060.27Aβ1-14-εK-KKK-MvF5 Th
<p>Aβ1-14-εK-KKK-MvF5 Th (UB311 immunogen I) is a biologically active peptide and one of the Aβ1–14 targeting peptides (B-cell epitope) used in UB-311.</p>Formule :C199H318N56O55Masse moléculaire :4372.38081Amyloid β-Protein (1-24)
CAS :<p>Amyloid β-Protein (1-24) is a peptide identified through peptide screening. This tool predominantly employs immunoassays to gather and analyze active peptides. Peptide screening is utilized in studies involving protein interactions, functional analysis, and epitope screening, particularly relevant in the research and development of active molecules.</p>Formule :C130H183N35O40Masse moléculaire :2876.05Aβ-IN-6
<p>Aβ-IN-6 is an orally active compound exhibiting anti-inflammatory, antioxidant, and anti-oligomeric activities, with significant implications for Alzheimer's</p>Formule :C28H31N3O4Couleur et forme :SolidMasse moléculaire :473.56FITC-β-Ala-Amyloid β-Protein (1-42) (ammonium)
<p>FITC-β-Ala-Amyloid β-Protein (1-42) (ammonium) is a FITC-labeled amyloid beta monomer, Alzheimer’s research, drug screening, and biomolecular studies.</p>Formule :C227H330N58O66S2Couleur et forme :SolidMasse moléculaire :4991.53LPYFD-NH2
CAS :<p>neuroprotective peptide that binds to amyloid beta (Aβ)</p>Formule :C33H44N6O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :652.742002-H20
CAS :<p>2002-H20 is an Aβ42-induced cytotoxicity inhibitor. It acts by binding the Alzheimer's Aβ peptide and reducing its cytotoxicity.</p>Formule :C20H15N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :345.358β-Amyloid (22-35)
CAS :<p>β-Amyloid (22-35) is a 14-aa peptide, shows aggregates and induces neurotoxicity in the hippocampal cells.</p>Formule :C59H102N16O21SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1403.62β-Amyloid (1-38), mouse, rat
CAS :<p>β-Amyloid (1-38), derived from mice and rats, is a chemical compound comprising 38 amino acids, specifically residues 1-38 of the Aβ peptide.</p>Couleur et forme :SolidC18 L-erythro Ceramide (d18:1/18:0)
CAS :<p>C18 L-erythro Ceramide, a natural stereoisomer, inhibits rat brain mt-CDase with IC50 of 8.8 μM.</p>Formule :C36H71NO3Couleur et forme :SolidMasse moléculaire :565.95Aβ-IN-8
<p>Aβ-IN-8, also known as compound 7e, is a potent inhibitor of Aβ aggregation [1].</p>Formule :C22H16F3N3O3SCouleur et forme :SolidMasse moléculaire :459.44BSB
CAS :<p>BSB is a Congo red-derived fluorescent probe, an amyloid protein imaging agent, interacting with amyloid fibrils formed by Aβ (1-40) peptides in rodents.</p>Formule :C24H17BrO6Degré de pureté :95.53%Couleur et forme :SolidMasse moléculaire :481.29β-Amyloid (1-20)
CAS :<p>This synthetic peptide consists of amino acids 1 to 20 of beta amyloid protein.</p>Formule :C113H157N31O32Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2461.7Amyloid-Forming peptide GNNQQNY
CAS :<p>Amyloid-Forming peptide GNNQQNY, a biologically active heptapeptide derived from the N-terminal prion-determining domain of yeast Sup35, is instrumental in</p>Formule :C33H48N12O14Couleur et forme :SolidMasse moléculaire :836.81(Met(O)35)-Amyloid β-Protein (1-42)
<p>(Met(O)35)-Amyloid β-Protein (1-42) represents the oxidized form of Methionine 35 in Aβ42, capable of producing an oligomer size distribution akin to that of</p>Formule :C203H311N55O61SCouleur et forme :SolidMasse moléculaire :4530.04Biphenyl-3′,3,4,4′-tetrol
CAS :<p>Biphenyl-3′,3,4,4′-tetrol (BPT) is a potent inhibitor of Aβ40 aggregation and can be utilized in research related to neurodegenerative diseases such as Alzheimer's.</p>Formule :C12H10O4Couleur et forme :SolidMasse moléculaire :218.21Glycerophosphorylethanolamine (sodium salt)
CAS :<p>Glycerophosphorylethanolamine, a phosphatidylethanolamine metabolite, elevates in Alzheimer's and promotes Aβ40 aggregation.</p>Formule :C5H13NNaO6PCouleur et forme :SolidMasse moléculaire :237.12G923-0271
CAS :<p>G923-0271 is a TDP-43 inhibitor that improves disease phenotypes in TDP-43 nematode models and reduces the overexpression of human TDP-43, ALS FTD.</p>Formule :C28H23FN4OCouleur et forme :SolidMasse moléculaire :450.51β-Amyloid (4-10)
CAS :<p>Antibodies corresponding to beta-amyloid (4-10) are effective in vivo inhibitors of cytotoxicity, amyloid plaque formation and special memory disturbances in</p>Formule :C39H52N12O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :880.9Methoxy-X04
CAS :<p>Methoxy-X04, a derivative of Congo red and Chrysamine-G, is a brain-permeable fluorescent probe for amyloid-β (Aβ).</p>Formule :C23H20O3Degré de pureté :98.96%Couleur et forme :SolidMasse moléculaire :344.4FITC-β-Ala-Amyloid β-Protein (1-42)
CAS :<p>FITC-β-Ala-Amyloid β-Protein (1-42) is a polypeptide identified through peptide screening. This screening method predominantly utilizes immunoassays to gather active polypeptides and is used in studying protein interactions, conducting functional analyses, and screening antigen epitopes, with particular application in the research and development of active molecules.</p>Formule :C227H327N57O66S2Masse moléculaire :4971.34251Pep63
CAS :Pep63, a neuroprotective peptide (VFQVRARTVA), enhances synaptic plasticity and memory. It competitively binds with Aβ1-42 oligomers, thereby inhibiting the formation of Aβ fibrils. Pep63 is employed in research focused on Alzheimer's disease (AD).Formule :C51H87N17O13Masse moléculaire :1146.34Dalidnetug
CAS :<p>Dalidnetug is a humanized monoclonal antibody that targets human β-amyloid precursor protein (APP). By specifically binding to APP, Dalidnetug reduces the production of β-amyloid (Aβ), thereby demonstrating activity in clearing β-amyloid. This compound holds potential for research in Alzheimer's disease.</p>Couleur et forme :LiquidSQ-3
<p>SQ-3, a quinoline analogue, prefers α-syn (Ki=39.3nM) to Aβ (Ki=230nM), and [18F]SQ3 is a lead for α-syn probes. [1]</p>Formule :C21H21FN2OCouleur et forme :SolidMasse moléculaire :336.4β-Amyloid (1-28)
CAS :<p>β-Amyloid (1-28) is a β-Amyloid protein fragment involved in metal binding.</p>Formule :C145H209N41O46Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3262.51β-Amyloid (10-35), amide
CAS :<p>β-Amyloid (10-35), amide, is a chemical compound consisting of 26 amino acids, specifically residues 10-35 of the Aβ peptide.</p>Formule :C133H205N35O36SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :2902.33β-Amyloid (1-11)
CAS :<p>Anionic interaction of Beta-amyloid (1-11) with Factor XII is suspected to cause massive activation of the C4 (complement 4) system in the cerebrospinal fluid</p>Formule :C56H76N16O22Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1325.3Crenezumab
CAS :<p>Crenezumab (MABT 5102A) is a fully humanized anti-amyloid-beta antibody that binds to multiple forms of amyloid-beta (Aβ) for the study of Alzheimer's disease.</p>Degré de pureté :97.5% (SDS-PAGE); 95.3% (SEC-HPLC) - 97.5% (SDS-PAGE); 95.3% (SEC-HPLC)Couleur et forme :Liquidβ-Amyloid (1-43)(human) TFA
<p>β-Amyloid (1-43)(human) TFA exhibits greater aggregation tendencies and heightened toxicity compared to its well-established counterpart, Aβ1-42.</p>Formule :C209H319F3N56O64SCouleur et forme :SolidMasse moléculaire :4729.21(D-Asp1)-Amyloid β-Protein (1-42)
CAS :<p>(D-Asp1)-Amyloid β-Protein (1-42), a peptide fragment of amyloid β-protein (Aβ), serves as the primary constituent of vascular and parenchymal amyloid deposits</p>Formule :C203H311N55O60SCouleur et forme :SolidMasse moléculaire :4514.04JNK3 inhibitor-9
<p>JNK3inhibitor-9 (Compound 24a) is a potent, selective JNK3 inhibitor capable of crossing the blood-brain barrier (BBB), demonstrating an IC50 value of 12 nM. It effectively inhibits GSK3α/β, which is involved in Tau phosphorylation, with IC50 values of 14 nM and 35 nM, respectively. JNK3inhibitor-9 also reduces the phosphorylation of c-Jun and APP and protects neurons from Aβ1-42 toxicity.</p>Formule :C25H27N7O2Couleur et forme :SolidMasse moléculaire :457.528Biotin-β-Amyloid (1-42), human TFA
<p>Biotin-β-Amyloid (1-42), human TFA, also known as Biotin-Amyloid β-Peptide (1-42) (human) TFA, is a biotin-labeled 42-amino acid peptide implicated in the</p>Formule :C215H326F3N57O64S2Couleur et forme :SolidMasse moléculaire :4854.36β-Amyloid (29-40)
CAS :<p>β-Amyloid (29-40) is a fragment of Amyloid-β peptide.Alzheimer's beta amyloid peptide (29-40/42) C-terminal fragments have physical and chemical properties</p>Formule :C49H88N12O13SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1085.36AChE/Aβ-IN-6
<p>BACE1-IN-15 (compound 4j) serves as an effective inhibitor of BACE1 (β-secretase), efficiently mitigating the copper-induced toxicity of Aβ, with an EC50 value of 0.68 μM.</p>Couleur et forme :Odour Solid(Met(O2)35)-Amyloid β-Protein (1-42)
<p>(Met(O2)35)-Amyloid β-Protein (1-42) is a peptide [1] .</p>Formule :C203H311N55O62SCouleur et forme :SolidMasse moléculaire :4546.04(Glu20)-Amyloid β-Protein (1-42)
CAS :<p>(Glu20)-Amyloid β-Protein (1-42) represents a variant of amyloid β-protein (Aβ) that fibrillizes more slowly.</p>Formule :C199H309N55O62SCouleur et forme :SolidMasse moléculaire :4495.98DDC 2′,3′-O-disulfate
<p>DDC 2′,3′-O-disulfate (compound 4) inhibits the fibrillization and oligomerization of Aβ42, showing promise for Alzheimer's disease (AD) research [1].</p>Formule :C17H16O11S2Couleur et forme :SolidMasse moléculaire :460.43β-Amyloid (22-40)
CAS :<p>This synthetic peptide consists of amino acids 22 to 40 of beta amyloid protein.</p>Formule :C78H135N21O26SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1815.1Amyloid β-Protein (3-42)
CAS :<p>Amyloid β-Protein (3-42), the precursor of Pyr peptide, serves as the foundation of the amyloid template block in Alzheimer's disease when modified to</p>Couleur et forme :SolidAducanumab
CAS :<p>Aducanumab (BIIB037) is an IgG1 antibody targeting amyloid beta to treat Alzheimer's; it's brain-permeable.</p>Degré de pureté :95% - 97.10%Couleur et forme :LiquidMasse moléculaire :145.93 kDaβ-Amyloid (13-27)
CAS :<p>β-Amyloid (13-27) is a peptide consisting of amino acid of 13 to 27 of beta amyloid protein.</p>Formule :C84H126N24O24Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1856.057-Deoxy-trans-dihydronarciclasine
CAS :<p>7-Deoxy-trans-dihydronarciclasine is an alkaloid that functions as a tobacco mosaic virus (TMV) inhibitor with an IC50 of 1.80 μM and also serves as an anti-</p>Formule :C14H15NO6Couleur et forme :SolidMasse moléculaire :293.27β-Amyloid (11-22)
CAS :<p>β-Amyloid (11-22) is a peptide fragment of β-Amyloid.Beta-amyloid peptide (Abeta), the major constituent of amyloid plaques in the brains of Alzheimer’s</p>Formule :C70H102N18O18Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1483.67p-HTAA
CAS :<p>Pentamer Hydrogen Thiophene Acetic Acid (p-HTAA) is a compound that specifically targets and labels amyloid-beta (Aβ) deposits in the brains of living mice [1].</p>Formule :C24H16O4S5Couleur et forme :SolidMasse moléculaire :528.71mcK6A1
<p>mcK6A1 serves as an inhibitor of amyloid-β (Aβ) aggregation, selectively binding to the 16KLVFFA21 fragment of Aβ42, leading to the formation of an extended β-sheet structure and preventing the formation of Aβ42 oligomers. This compound is valuable for research into Alzheimer's disease and other amyloid-related disorders.</p>Formule :C71H99N17O16Couleur et forme :SolidMasse moléculaire :1446.65Biotinoyl tripeptide-1
CAS :<p>Biotinoyl tripeptide-1 can produce hair follicles by promoting scalp micro-circulation and reduce follicle atrophy and aging.</p>Formule :C24H38N8O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :566.67β-Amyloid (1-16)
CAS :<p>β-Amyloid (1-16) is an amyloidogenic protein fragment with a sequence derived from β-amyloid.</p>Formule :C84H119N27O28Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1955.04β-Amyloid (33-40)
CAS :<p>β-Amyloid (33-40) is a peptide comprising amino acids 33 to 40 of the beta-amyloid protein.</p>Formule :C32H58N8O9SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :730.92AC 253
CAS :<p>Amylin (AMY3) receptor antagonist; blocks cAMP, Ca2+, PKA, MAPK, Akt, and cFOS activity; prevents Aβ-induced neuronal death. Cyclic AC 253 variant exists.</p>Formule :C122H196N40O39Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2847.11Acetyl-Tau Peptide (273-284) amide
CAS :<p>Acetyl-Tau Peptide (273-284) amide inhibits Ac-Aβ(25–35)-NH2 aggregation and models Aβ/Tau interaction.</p>Formule :C64H116N18O17Couleur et forme :SolidMasse moléculaire :1409.72β-Amyloid (1-9)
CAS :<p>This is an N-terminal fragment of beta amyloid.</p>Formule :C42H60N14O17Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1033.01Chemerin-9 (149-157) TFA
<p>Chemerin-9 (149-157) TFA is a peptide located at positions 149-157 of chemerin-9, acting as a ChemR23/CMKLR1 agonist.</p>Formule :C56H67F3N10O15Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :1177.18CHF-5022
CAS :<p>CHF-5022 is a nonsteroidal anti-inflammatory drug that selectively inhibits the production of beta-amyloid protein (1-42) (ABETA42).</p>Formule :C17H12F4O2Couleur et forme :SolidMasse moléculaire :324.27β-Amyloid Protein Precursor 770 (135-155)
CAS :<p>Beta-Amyloid Protein Precursor 770 (135-155)Aβ Protein Precursor 770 (135-155)</p>Formule :C116H172N35O31S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2617.962,3-Dehydrosilybin A
CAS :<p>2,3-Dehydrosilybin A is a useful organic compound for research related to life sciences and the catalog number is T125202.</p>Formule :C25H20O10Couleur et forme :SolidMasse moléculaire :480.425GSK-3β inhibitor 27
<p>GSK-3β inhibitor27 (Compound 1c) is a reversible, competitive inhibitor of GSK-3β with an IC50 value of 2.2 μM. It inhibits tau hyperphosphorylation and reduces Aβ protein aggregation, demonstrating metal chelation and neuroprotective potential. GSK-3β inhibitor27 is promising for research into neurodegenerative diseases, such as Alzheimer's disease.</p>Formule :C16H17ClN4O2Couleur et forme :SolidMasse moléculaire :332.79Anti-Amyloid β Antibody (scFv59)
<p>Anti-Amyloid Beta Antibody (scFv59) is a human-derived antibody produced in CHO cells that targets Amyloid-β. For isotype control, please refer to Human IgG1 kappa, Isotype Control.</p>Couleur et forme :Odour Liquid5-FAM-β-Amyloid (1-28)
<p>5-FAM-β-Amyloid (1-28) is a fluorescently-labeled peptide corresponding to the first 28 amino acids of the β-Amyloid protein.</p>Formule :C166H219N41O52Couleur et forme :SolidMasse moléculaire :3620.76β-Amyloid (1-17)
CAS :<p>This synthetic peptide consists of amino acids 1 to 17 of beta amyloid protein. This peptide can be employed in beta amyloid solubility studies.</p>Formule :C90H130N28O29Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2068.2δ-secretase inhibitor 11
CAS :<p>δ-secretase inhibitor 11 is an inhibitor of δ-secretase and can be used as a lead compound for translational development of AD treatment.</p>Formule :C10H12N4O2Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :220.231H-Indole-3-carboxylic acid, 5-[2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]propoxy]-2-methyl-1-(4-methylphenyl)-, ethyl ester
CAS :<p>Compound 5936-0108对β-淀粉样蛋白可能具有调节作用。</p>Formule :C26H34N2O7Degré de pureté :99.44%Couleur et forme :SoildMasse moléculaire :486.56β-Amyloid (12-28)
CAS :<p>Amyloid β-peptide fragment; minimum section required to bind to brain proteins.</p>Formule :C89H135N25O25Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1955.18AZD4694 Precursor
CAS :<p>AZD4694 Precursor used for synthesizing [18F]AZD4694, a high-affinity amyloid-β imaging agent.</p>Formule :C22H25N3O7Couleur et forme :SolidMasse moléculaire :443.45RAGE antagonist peptide
CAS :<p>RAGE antagonist blocks S100P/A4, HMGB-1; hinders glioma growth, metastasis; reduces PDAC cell growth, NF-κB activity; counters TDI effects in mice.</p>Formule :C57H101N13O17SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1272.56β-Amyloid (18-28)
CAS :<p>Intracerebroventricular administration of synthetic peptides Beta-amyloid (12-20), (12-28), and (18-28) causes amnesia in mice.</p>Formule :C55H81N13O18Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1212.31β-Amyloid (10-20)
CAS :<p>Amyloid β-Protein (10-20) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Amyloid β protein fragment containing the α-</p>Formule :C71H99N17O16Degré de pureté :98%Couleur et forme :Lyophilized PowderMasse moléculaire :1446.65Sabirnetug
CAS :<p>Sabirnetug is a humanized IgG2κ monoclonal antibody that specifically targets the amyloid-β (A4) precursor protein.</p>Couleur et forme :Liquidγ-Secretase Modulators
CAS :<p>gamma-Secretase Modulators serves as a useful treatment for Alzheimer's disease by inhibiting the production of Amyloid-β.</p>Formule :C26H24F3N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :483.48Davunetide
CAS :<p>Davunetide: neuroprotective 8-amino acid peptide, improves daily function in schizophrenia, boosts memory in mild cognitive impairment.</p>Formule :C36H60N10O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :824.92BIBD-124
CAS :<p>BIBD-124, with an IC50 value of 9.51 nM, effectively binds to amyloid beta (Aβ) plaques.</p>Formule :C19H24FN3O3Couleur et forme :SolidMasse moléculaire :361.41SEN177
CAS :<p>SEN177 shows the potential in the research of Huntington's disease that is a potent inhibitor of glutaminyl cyclase (QPCT) with an IC 50 of 0.013μM for glutaminyl-peptide cyclotransferase-like (QPCTL). The Ki value of SEN177 for human glutaminyl cyclase (hQC) is 20 nM. SEN177 significantly reduces the early stages of mutant HTT oligomerisation and reduces the percentage of neurons with Q80 aggregates [1].</p>Formule :C18H19FN6Couleur et forme :SolidMasse moléculaire :338.38TH-237A
CAS :<p>TH-237A is a novel neuroprotective agent exhibiting favorable permeation across the blood-brain barrier.</p>Formule :C18H17F2NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :333.335Begacestat
CAS :Begacestat (GSI-953) is a potent and selective gamma-secretase inhibitor that inhibits Amyloid-beta, inhibits cleavage of APP,,Alzheimer's disease.Formule :C9H8ClF6NO3S2Couleur et forme :SolidMasse moléculaire :391.74(Rac)-Z-Phe-Phe-FMK
CAS :<p>(Rac)-Z-Phe-Phe-FMK (Cathepsin L-IN-2) is a cathepsin L inhibitor that inhibits the tendency of β-amyloid to induce apoptotic changes .</p>Formule :C27H27FN2O4Degré de pureté :98.27%Couleur et forme :SolidMasse moléculaire :462.51AZD4694
CAS :<p>Flutafuranol (AZD4694/NAV4694) binds beta-amyloid, potential PET tracer for Alzheimer's. Non-F18 version supplied.</p>Formule :C14H11FN2O2Couleur et forme :SolidMasse moléculaire :258.25Cu(II)GTSM
CAS :<p>Cu(II)GTSM is a cell permeable copper complex inhibits GSK3β activity and suppresses levels of neurotoxic amyloid β-trimers and phosphorylated tau.</p>Formule :C6H10CuN6S2Degré de pureté :99.21%Couleur et forme :SolidMasse moléculaire :293.86Pyridoxal 5'-phosphate hydrate
CAS :<p>Pyridoxal 5'-phosphate hydrate (PLP)(1:x), the active form of vitamin B6, is a cofactor for many different enzymes involved in transamination reactions,</p>Formule :C8H10NO6PDegré de pureté :97.52%Couleur et forme :SolidMasse moléculaire :247.141,1'-Methylenedi-2-naphthol
CAS :<p>1,1'-Methylenedi-2-naphthol target CYP2C19 - cytochrome P450 family 2 subfamily C member 19 (human).</p>Formule :C21H16O2Degré de pureté :98.91%Couleur et forme :Light Pink To Light Brown Crystalline PowderMasse moléculaire :300.35Miridesap
CAS :<p>Miridesap (GSK2315698) rapidly depletes SAP in blood, cerebrospinal fluid, and amyloid deposits via liver clearance.</p>Formule :C16H24N2O6Degré de pureté :≥95%Couleur et forme :SolidMasse moléculaire :340.37PiB
CAS :<p>PiB (Pittsburgh Compound-B) is a standard for analysis of 11C-PiB. 11C-PiB is a β-amyloid PET imaging tracer for Alzheimer's disease diagnosis.</p>Formule :C14H12N2OSDegré de pureté :97.02%Couleur et forme :SolidMasse moléculaire :256.32CRANAD 2
CAS :<p>CRANAD-2, a near-infrared probe, detects amyloid-beta in vivo, increasing fluorescence 70x and shifting blue 90 nm upon binding.</p>Formule :C23H25BF2N2O2Degré de pureté :99.44%Couleur et forme :Dark Blue To Black PowderMasse moléculaire :410.27
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