Bêta-amyloïde
Les inhibiteurs de bêta-amyloïde sont des composés qui ciblent spécifiquement et inhibent la formation ou l'agrégation des peptides bêta-amyloïdes, impliqués de manière critique dans la pathogenèse de la maladie d'Alzheimer. L'accumulation de plaques bêta-amyloïdes dans le cerveau est l'un des principaux signes pathologiques de la maladie d'Alzheimer, contribuant à la dysfonction neuronale, à la perte synaptique et au déclin cognitif. En empêchant l'agrégation des bêta-amyloïdes, ces inhibiteurs font l'objet de recherches intensives comme agents thérapeutiques potentiels visant à ralentir ou même arrêter la progression de la maladie d'Alzheimer. Chez CymitQuimica, nous proposons une variété d'inhibiteurs de bêta-amyloïde de haute qualité pour soutenir vos recherches sur les troubles neurodégénératifs, l'agrégation des protéines et le développement de thérapies pour la maladie d'Alzheimer.
205 produits trouvés pour "Bêta-amyloïde"
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ALZ-801
CAS :<p>ALZ-801, an oral valine-prodrug of tramiprosate, enhances treatment of Alzheimer's by inhibiting β-amyloid aggregation with better PK and tolerance.</p>Formule :C8H18N2O4SDegré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :238.3Glimepiride
CAS :<p>Glimepiride (HOE-490) is a long-acting, third-generation sulfonylurea with hypoglycemic activity.</p>Formule :C24H34N4O5SDegré de pureté :97.84% - 98.87%Couleur et forme :White Cyrstalline SolidMasse moléculaire :490.62Eprodisate disodium
CAS :<p>Eprodisate disodium (NC-503) is a negatively charged sulfonated inhibitor of fibrillogenesis, that can be used in the treatment of amyloid A (AA) amyloidosis.</p>Formule :C3H6Na2O6S2Degré de pureté :99.88%Couleur et forme :White Coarse PowderMasse moléculaire :248.19Gantenerumab
CAS :<p>Gantenerumab (R-1450) is a humanized antibody targeting amyloid-β (Aβ), used in studies of Alzheimer's disease.</p>Degré de pureté :>95%Couleur et forme :LiquidBirtamimab
CAS :<p>Birtamimab (NEOD001) is a monoclonal antibody selectively targeting and depleting amyloid protein, used in research on light chain amyloidosis.</p>Degré de pureté :>95%Couleur et forme :LiquidLY 2389575 hydrochloride
CAS :<p>LY2389575 hydrochloride is a selective mGlu3 NAM with 190 nM IC50, increases Mrc1, and aids Alzheimer's research.</p>Formule :C15H16BrCl3N4Degré de pureté :99.45%Couleur et forme :SolidMasse moléculaire :438.58Lecanemab
CAS :<p>Lecanemab (BAN-2401) is an IgG1 monoclonal antibody targeting soluble aggregated beta amyloid (Abeta) for the study of cognitive disorders.</p>Degré de pureté :95% - 97.3% (SEC-HPLC)Couleur et forme :LiquidDonanemab
CAS :<p>Donanemab (LY3002813), a humanized IgG1 antibody, targets N-terminal Aβ for potential early Alzheimer's research.</p>Degré de pureté :95%Couleur et forme :LiquidChlorzoxazone
CAS :<p>Chlorzoxazone (Chlorzoxazon) is a Muscle Relaxant. The physiologic effect of chlorzoxazone is by means of Centrally-mediated Muscle Relaxation.</p>Formule :C7H4ClNO2Degré de pureté :99.49% - 99.6%Couleur et forme :SolidMasse moléculaire :169.57Cromolyn sodium
CAS :<p>Cromolyn sodium (FPL-670) is a chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells.</p>Formule :C23H14Na2O11Degré de pureté :99.4% - 99.95%Couleur et forme :Colorless Crystals From Ethanol + Ether White Crystalline PowderMasse moléculaire :512.33AZD4694 Precursor
CAS :<p>AZD4694 Precursor used for synthesizing [18F]AZD4694, a high-affinity amyloid-β imaging agent.</p>Formule :C22H25N3O7Couleur et forme :SolidMasse moléculaire :443.45β-Amyloid (18-28)
CAS :<p>Intracerebroventricular administration of synthetic peptides Beta-amyloid (12-20), (12-28), and (18-28) causes amnesia in mice.</p>Formule :C55H81N13O18Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1212.31BIBD-124
CAS :<p>BIBD-124, with an IC50 value of 9.51 nM, effectively binds to amyloid beta (Aβ) plaques.</p>Formule :C19H24FN3O3Couleur et forme :SolidMasse moléculaire :361.41Aβ-IN-7
<p>Aβ-IN-7 (compound 5a) acts as a potent inhibitor of Aβ aggregation, stabilizing Aβ monomers at 50 μM concentration to prevent them from forming larger oligomers</p>Formule :C14H10N2SCouleur et forme :SolidMasse moléculaire :238.31β-Amyloid (1-11)
CAS :<p>Anionic interaction of Beta-amyloid (1-11) with Factor XII is suspected to cause massive activation of the C4 (complement 4) system in the cerebrospinal fluid</p>Formule :C56H76N16O22Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1325.3Aβ-IN-8
<p>Aβ-IN-8, also known as compound 7e, is a potent inhibitor of Aβ aggregation [1].</p>Formule :C22H16F3N3O3SCouleur et forme :SolidMasse moléculaire :459.44Anti-Amyloid β Antibody (scFv59)
<p>Anti-Amyloid Beta Antibody (scFv59) is a human-derived antibody produced in CHO cells that targets Amyloid-β. For isotype control, please refer to Human IgG1 kappa, Isotype Control.</p>Couleur et forme :Odour Liquid2,3-Dehydrosilybin A
CAS :<p>2,3-Dehydrosilybin A is a useful organic compound for research related to life sciences and the catalog number is T125202.</p>Formule :C25H20O10Couleur et forme :SolidMasse moléculaire :480.4255-FAM-β-Amyloid (1-28)
<p>5-FAM-β-Amyloid (1-28) is a fluorescently-labeled peptide corresponding to the first 28 amino acids of the β-Amyloid protein.</p>Formule :C166H219N41O52Couleur et forme :SolidMasse moléculaire :3620.761H-Indole-3-carboxylic acid, 5-[2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]propoxy]-2-methyl-1-(4-methylphenyl)-, ethyl ester
CAS :<p>Compound 5936-0108对β-淀粉样蛋白可能具有调节作用。</p>Formule :C26H34N2O7Degré de pureté :99.44%Couleur et forme :SoildMasse moléculaire :486.56β-Amyloid (1-28)
CAS :<p>β-Amyloid (1-28) is a β-Amyloid protein fragment involved in metal binding.</p>Formule :C145H209N41O46Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3262.51β-Amyloid (10-35), amide
CAS :<p>β-Amyloid (10-35), amide, is a chemical compound consisting of 26 amino acids, specifically residues 10-35 of the Aβ peptide.</p>Formule :C133H205N35O36SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :2902.33AC 253
CAS :<p>Amylin (AMY3) receptor antagonist; blocks cAMP, Ca2+, PKA, MAPK, Akt, and cFOS activity; prevents Aβ-induced neuronal death. Cyclic AC 253 variant exists.</p>Formule :C122H196N40O39Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2847.11SQ-3
<p>SQ-3, a quinoline analogue, prefers α-syn (Ki=39.3nM) to Aβ (Ki=230nM), and [18F]SQ3 is a lead for α-syn probes. [1]</p>Formule :C21H21FN2OCouleur et forme :SolidMasse moléculaire :336.4LPYFD-NH2
CAS :<p>neuroprotective peptide that binds to amyloid beta (Aβ)</p>Formule :C33H44N6O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :652.74β-Amyloid (1-17)
CAS :<p>This synthetic peptide consists of amino acids 1 to 17 of beta amyloid protein. This peptide can be employed in beta amyloid solubility studies.</p>Formule :C90H130N28O29Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2068.2β-Amyloid (22-35)
CAS :<p>β-Amyloid (22-35) is a 14-aa peptide, shows aggregates and induces neurotoxicity in the hippocampal cells.</p>Formule :C59H102N16O21SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1403.62β-Amyloid (22-40)
CAS :<p>This synthetic peptide consists of amino acids 22 to 40 of beta amyloid protein.</p>Formule :C78H135N21O26SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1815.1Aducanumab
CAS :<p>Aducanumab (BIIB037) is an IgG1 antibody targeting amyloid beta to treat Alzheimer's; it's brain-permeable.</p>Degré de pureté :95% - 97.10%Couleur et forme :LiquidMasse moléculaire :145.93 kDaSabirnetug
CAS :<p>Sabirnetug is a humanized IgG2κ monoclonal antibody that specifically targets the amyloid-β (A4) precursor protein.</p>Couleur et forme :Liquidβ-Amyloid (12-20)
CAS :<p>β-Amyloid (12-20) is a peptide fragment of β-Amyloid.Thsis peptide contain the amino acid residues VFF at position (18-20), suggesting that this triad has</p>Formule :C57H83N15O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1154.36β-Amyloid (35-42)
CAS :<p>β-Amyloid (35-42) is a peptide derived from the beta-amyloid protein, encompassing amino acids 35 through 42.</p>Formule :C33H60N8O9SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :744.94β-Amyloid (29-40)
CAS :<p>β-Amyloid (29-40) is a fragment of Amyloid-β peptide.Alzheimer's beta amyloid peptide (29-40/42) C-terminal fragments have physical and chemical properties</p>Formule :C49H88N12O13SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1085.36β-Amyloid Protein Precursor 770 (135-155)
CAS :<p>Beta-Amyloid Protein Precursor 770 (135-155)Aβ Protein Precursor 770 (135-155)</p>Formule :C116H172N35O31S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2617.96Chemerin-9 (149-157) TFA
<p>Chemerin-9 (149-157) TFA is a peptide located at positions 149-157 of chemerin-9, acting as a ChemR23/CMKLR1 agonist.</p>Formule :C56H67F3N10O15Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :1177.18CHF-5022
CAS :<p>CHF-5022 is a nonsteroidal anti-inflammatory drug that selectively inhibits the production of beta-amyloid protein (1-42) (ABETA42).</p>Formule :C17H12F4O2Couleur et forme :SolidMasse moléculaire :324.27GSK-3β inhibitor 27
<p>GSK-3β inhibitor27 (Compound 1c) is a reversible, competitive inhibitor of GSK-3β with an IC50 value of 2.2 μM. It inhibits tau hyperphosphorylation and reduces Aβ protein aggregation, demonstrating metal chelation and neuroprotective potential. GSK-3β inhibitor27 is promising for research into neurodegenerative diseases, such as Alzheimer's disease.</p>Formule :C16H17ClN4O2Couleur et forme :SolidMasse moléculaire :332.79β-Amyloid (4-10)
CAS :<p>Antibodies corresponding to beta-amyloid (4-10) are effective in vivo inhibitors of cytotoxicity, amyloid plaque formation and special memory disturbances in</p>Formule :C39H52N12O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :880.9Methoxy-X04
CAS :<p>Methoxy-X04, a derivative of Congo red and Chrysamine-G, is a brain-permeable fluorescent probe for amyloid-β (Aβ).</p>Formule :C23H20O3Degré de pureté :98.96%Couleur et forme :SolidMasse moléculaire :344.4β-Amyloid (12-28)
CAS :<p>Amyloid β-peptide fragment; minimum section required to bind to brain proteins.</p>Formule :C89H135N25O25Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1955.18RAGE antagonist peptide
CAS :<p>RAGE antagonist blocks S100P/A4, HMGB-1; hinders glioma growth, metastasis; reduces PDAC cell growth, NF-κB activity; counters TDI effects in mice.</p>Formule :C57H101N13O17SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1272.56β-Amyloid (10-20)
CAS :<p>Amyloid β-Protein (10-20) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Amyloid β protein fragment containing the α-</p>Formule :C71H99N17O16Degré de pureté :98%Couleur et forme :Lyophilized PowderMasse moléculaire :1446.65β-Amyloid (1-20)
CAS :<p>This synthetic peptide consists of amino acids 1 to 20 of beta amyloid protein.</p>Formule :C113H157N31O32Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2461.7β-Amyloid (1-40)
CAS :<p>Amyloid β1-40 is one of the fragments generated after cleavage of the amyloid peptide precursor protein by β and γ secretases.</p>Formule :C194H295N53O58SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :4329.82β-Amyloid (33-40)
CAS :<p>β-Amyloid (33-40) is a peptide comprising amino acids 33 to 40 of the beta-amyloid protein.</p>Formule :C32H58N8O9SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :730.92γ-Secretase Modulators
CAS :<p>gamma-Secretase Modulators serves as a useful treatment for Alzheimer's disease by inhibiting the production of Amyloid-β.</p>Formule :C26H24F3N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :483.48Aβ-IN-6
<p>Aβ-IN-6 is an orally active compound exhibiting anti-inflammatory, antioxidant, and anti-oligomeric activities, with significant implications for Alzheimer's</p>Formule :C28H31N3O4Couleur et forme :SolidMasse moléculaire :473.567-Deoxy-trans-dihydronarciclasine
CAS :<p>7-Deoxy-trans-dihydronarciclasine is an alkaloid that functions as a tobacco mosaic virus (TMV) inhibitor with an IC50 of 1.80 μM and also serves as an anti-</p>Formule :C14H15NO6Couleur et forme :SolidMasse moléculaire :293.27β-Amyloid (11-22)
CAS :<p>β-Amyloid (11-22) is a peptide fragment of β-Amyloid.Beta-amyloid peptide (Abeta), the major constituent of amyloid plaques in the brains of Alzheimer’s</p>Formule :C70H102N18O18Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1483.67Davunetide
CAS :<p>Davunetide: neuroprotective 8-amino acid peptide, improves daily function in schizophrenia, boosts memory in mild cognitive impairment.</p>Formule :C36H60N10O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :824.92
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