Bêta-amyloïde
Les inhibiteurs de bêta-amyloïde sont des composés qui ciblent spécifiquement et inhibent la formation ou l'agrégation des peptides bêta-amyloïdes, impliqués de manière critique dans la pathogenèse de la maladie d'Alzheimer. L'accumulation de plaques bêta-amyloïdes dans le cerveau est l'un des principaux signes pathologiques de la maladie d'Alzheimer, contribuant à la dysfonction neuronale, à la perte synaptique et au déclin cognitif. En empêchant l'agrégation des bêta-amyloïdes, ces inhibiteurs font l'objet de recherches intensives comme agents thérapeutiques potentiels visant à ralentir ou même arrêter la progression de la maladie d'Alzheimer. Chez CymitQuimica, nous proposons une variété d'inhibiteurs de bêta-amyloïde de haute qualité pour soutenir vos recherches sur les troubles neurodégénératifs, l'agrégation des protéines et le développement de thérapies pour la maladie d'Alzheimer.
228 produits trouvés pour "Bêta-amyloïde"
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LY 2389575 hydrochloride
CAS :LY2389575 hydrochloride is a selective mGlu3 NAM with 190 nM IC50, increases Mrc1, and aids Alzheimer's research.Formule :C15H16BrCl3N4Degré de pureté :99.9%Couleur et forme :SolidMasse moléculaire :438.58ALZ-801
CAS :ALZ-801, an oral valine-prodrug of tramiprosate, enhances treatment of Alzheimer's by inhibiting β-amyloid aggregation with better PK and tolerance.Formule :C8H18N2O4SDegré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :238.3Donanemab
CAS :Donanemab (LY3002813), a humanized IgG1 antibody, targets N-terminal Aβ for potential early Alzheimer's research.Degré de pureté :95%Couleur et forme :LiquidMasse moléculaire :145.36 kDaEprodisate disodium
CAS :Eprodisate disodium (NC-503) is a negatively charged sulfonated inhibitor of fibrillogenesis, that can be used in the treatment of amyloid A (AA) amyloidosis.Formule :C3H6Na2O6S2Degré de pureté :99.88%Couleur et forme :White Coarse PowderMasse moléculaire :248.19Lecanemab
CAS :Lecanemab (BAN-2401) is an IgG1 monoclonal antibody targeting soluble aggregated beta amyloid (Abeta) for the study of cognitive disorders.Degré de pureté :95% - >95.0% (SDS-PAGE); 100% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :147.06 kDaBirtamimab
CAS :Birtamimab (NEOD001) is a monoclonal antibody selectively targeting and depleting amyloid protein, used in research on light chain amyloidosis.Degré de pureté :>95%Couleur et forme :LiquidMasse moléculaire :146.44 kDaGantenerumab
CAS :Gantenerumab (R-1450) is a humanized antibody targeting amyloid-β (Aβ), used in studies of Alzheimer's disease.Degré de pureté :>95%Couleur et forme :LiquidMasse moléculaire :146.28 kDaGlimepiride
CAS :Glimepiride (HOE-490) is a long-acting, third-generation sulfonylurea with hypoglycemic activity.Formule :C24H34N4O5SDegré de pureté :97.84% - 98.87%Couleur et forme :White Cyrstalline SolidMasse moléculaire :490.62Chlorzoxazone
CAS :Chlorzoxazone (Chlorzoxazon) is a Muscle Relaxant. The physiologic effect of chlorzoxazone is by means of Centrally-mediated Muscle Relaxation.Formule :C7H4ClNO2Degré de pureté :99.49% - 99.6%Couleur et forme :SolidMasse moléculaire :169.57Cromolyn sodium
CAS :Cromolyn sodium (FPL-670) is a chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells.Formule :C23H14Na2O11Degré de pureté :99.4% - 99.95%Couleur et forme :Colorless Crystals From Ethanol + Ether White Crystalline PowderMasse moléculaire :512.33DDC 2′,3′-O-disulfate
DDC 2′,3′-O-disulfate (compound 4) inhibits the fibrillization and oligomerization of Aβ42, showing promise for Alzheimer's disease (AD) research [1].Formule :C17H16O11S2Couleur et forme :SolidMasse moléculaire :460.43SQ-3
SQ-3, a quinoline analogue, prefers α-syn (Ki=39.3nM) to Aβ (Ki=230nM), and [18F]SQ3 is a lead for α-syn probes. [1]Formule :C21H21FN2OCouleur et forme :SolidMasse moléculaire :336.4β-Amyloid (1-34)
CAS :This is a fragment of beta-amyloid peptide. It has amino acids 1 through 34.Formule :C170H253N47O52Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3787.2BIBD-124
CAS :BIBD-124, with an IC50 value of 9.51 nM, effectively binds to amyloid beta (Aβ) plaques.Formule :C19H24FN3O3Couleur et forme :SolidMasse moléculaire :361.41β-Amyloid (12-20)
CAS :β-Amyloid (12-20) is a peptide fragment of β-Amyloid.Thsis peptide contain the amino acid residues VFF at position (18-20), suggesting that this triad hasFormule :C57H83N15O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1154.36Aβ-IN-8
Aβ-IN-8, also known as compound 7e, is a potent inhibitor of Aβ aggregation [1].Formule :C22H16F3N3O3SCouleur et forme :SolidMasse moléculaire :459.44Anti-Amyloid β Antibody (scFv59)
Anti-Amyloid Beta Antibody (scFv59) is a human-derived antibody produced in CHO cells that targets Amyloid-β. For isotype control, please refer to Human IgG1 kappa, Isotype Control.Couleur et forme :Odour Liquidβ-Amyloid (18-28)
CAS :Intracerebroventricular administration of synthetic peptides Beta-amyloid (12-20), (12-28), and (18-28) causes amnesia in mice.Formule :C55H81N13O18Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1212.31β-Amyloid (1-17)
CAS :This synthetic peptide consists of amino acids 1 to 17 of beta amyloid protein. This peptide can be employed in beta amyloid solubility studies.Formule :C90H130N28O29Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2068.2CHF-5022
CAS :CHF-5022 is a nonsteroidal anti-inflammatory drug that selectively inhibits the production of beta-amyloid protein (1-42) (ABETA42).Formule :C17H12F4O2Couleur et forme :SolidMasse moléculaire :324.272,3-Dehydrosilybin A
CAS :2,3-Dehydrosilybin A is a useful organic compound for research related to life sciences and the catalog number is T125202.Formule :C25H20O10Couleur et forme :SolidMasse moléculaire :480.435-FAM-β-Amyloid (1-28)
5-FAM-β-Amyloid (1-28) is a fluorescently-labeled peptide corresponding to the first 28 amino acids of the β-Amyloid protein.Formule :C166H219N41O52Couleur et forme :SolidMasse moléculaire :3620.76β-Amyloid (1-20)
CAS :This synthetic peptide consists of amino acids 1 to 20 of beta amyloid protein.Formule :C113H157N31O32Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2461.7Sabirnetug
CAS :Sabirnetug is a humanized IgG2κ monoclonal antibody that specifically targets the amyloid-β (A4) precursor protein.Couleur et forme :Liquidβ-Amyloid (33-40)
CAS :β-Amyloid (33-40) is a peptide comprising amino acids 33 to 40 of the beta-amyloid protein.Formule :C32H58N8O9SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :730.92β-Amyloid (13-27)
CAS :β-Amyloid (13-27) is a peptide consisting of amino acid of 13 to 27 of beta amyloid protein.Formule :C84H126N24O24Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1856.05β-Amyloid (1-16)
CAS :β-Amyloid (1-16) is an amyloidogenic protein fragment with a sequence derived from β-amyloid.Formule :C84H119N27O28Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1955.04Davunetide
CAS :Davunetide: neuroprotective 8-amino acid peptide, improves daily function in schizophrenia, boosts memory in mild cognitive impairment.Formule :C36H60N10O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :824.92GSK-3β inhibitor 27
GSK-3β inhibitor27 (Compound 1c) is a reversible, competitive inhibitor of GSK-3β with an IC50 value of 2.2 μM. It inhibits tau hyperphosphorylation and reduces Aβ protein aggregation, demonstrating metal chelation and neuroprotective potential. GSK-3β inhibitor27 is promising for research into neurodegenerative diseases, such as Alzheimer's disease.Formule :C16H17ClN4O2Couleur et forme :SolidMasse moléculaire :332.79Chemerin-9 (149-157) TFA
Chemerin-9 (149-157) TFA is a peptide located at positions 149-157 of chemerin-9, acting as a ChemR23/CMKLR1 agonist.Formule :C56H67F3N10O15Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :1177.18AC 253
CAS :Amylin (AMY3) receptor antagonist; blocks cAMP, Ca2+, PKA, MAPK, Akt, and cFOS activity; prevents Aβ-induced neuronal death. Cyclic AC 253 variant exists.Formule :C122H196N40O39Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2847.11β-Amyloid (1-11)
CAS :Anionic interaction of Beta-amyloid (1-11) with Factor XII is suspected to cause massive activation of the C4 (complement 4) system in the cerebrospinal fluidFormule :C56H76N16O22Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1325.3β-Amyloid (10-35), amide
CAS :β-Amyloid (10-35), amide, is a chemical compound consisting of 26 amino acids, specifically residues 10-35 of the Aβ peptide.Formule :C133H205N35O36SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :2902.33RAGE antagonist peptide
CAS :RAGE antagonist blocks S100P/A4, HMGB-1; hinders glioma growth, metastasis; reduces PDAC cell growth, NF-κB activity; counters TDI effects in mice.Formule :C57H101N13O17SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1272.56β-Amyloid (12-28)
CAS :Amyloid β-peptide fragment; minimum section required to bind to brain proteins.Formule :C89H135N25O25Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1955.18β-Amyloid (35-42)
CAS :β-Amyloid (35-42) is a peptide derived from the beta-amyloid protein, encompassing amino acids 35 through 42.Formule :C33H60N8O9SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :744.94β-Amyloid (10-20)
CAS :Amyloid β-Protein (10-20) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Amyloid β protein fragment containing the α-Formule :C71H99N17O16Degré de pureté :98%Couleur et forme :Lyophilized PowderMasse moléculaire :1446.65β-Amyloid (1-28)
CAS :β-Amyloid (1-28) is a β-Amyloid protein fragment involved in metal binding.Formule :C145H209N41O46Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3262.51β-Amyloid (1-40)
CAS :Amyloid β1-40 is one of the fragments generated after cleavage of the amyloid peptide precursor protein by β and γ secretases.Formule :C194H295N53O58SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :4329.82γ-Secretase Modulators
CAS :gamma-Secretase Modulators serves as a useful treatment for Alzheimer's disease by inhibiting the production of Amyloid-β.Formule :C26H24F3N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :483.48β-Amyloid (11-22)
CAS :β-Amyloid (11-22) is a peptide fragment of β-Amyloid.Beta-amyloid peptide (Abeta), the major constituent of amyloid plaques in the brains of Alzheimer’sFormule :C70H102N18O18Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1483.67Aβ-IN-6
Aβ-IN-6 is an orally active compound exhibiting anti-inflammatory, antioxidant, and anti-oligomeric activities, with significant implications for Alzheimer'sFormule :C28H31N3O4Couleur et forme :SolidMasse moléculaire :473.56LPYFD-NH2
CAS :neuroprotective peptide that binds to amyloid beta (Aβ)Formule :C33H44N6O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :652.74Aducanumab
CAS :Aducanumab (BIIB037) is an IgG1 antibody targeting amyloid beta to treat Alzheimer's; it's brain-permeable.
Degré de pureté :95% - 97.10%Couleur et forme :LiquidMasse moléculaire :145.93 kDaβ-Amyloid (22-35)
CAS :β-Amyloid (22-35) is a 14-aa peptide, shows aggregates and induces neurotoxicity in the hippocampal cells.Formule :C59H102N16O21SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1403.62β-Amyloid (29-40)
CAS :β-Amyloid (29-40) is a fragment of Amyloid-β peptide.Alzheimer's beta amyloid peptide (29-40/42) C-terminal fragments have physical and chemical propertiesFormule :C49H88N12O13SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1085.36β-Amyloid (22-40)
CAS :This synthetic peptide consists of amino acids 22 to 40 of beta amyloid protein.Formule :C78H135N21O26SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1815.17-Deoxy-trans-dihydronarciclasine
CAS :7-Deoxy-trans-dihydronarciclasine is an alkaloid that functions as a tobacco mosaic virus (TMV) inhibitor with an IC50 of 1.80 μM and also serves as an anti-Formule :C14H15NO6Couleur et forme :SolidMasse moléculaire :293.271H-Indole-3-carboxylic acid, 5-[2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]propoxy]-2-methyl-1-(4-methylphenyl)-, ethyl ester
CAS :Compound 5936-0108对β-淀粉样蛋白可能具有调节作用。
Formule :C26H34N2O7Degré de pureté :99.44%Couleur et forme :SoildMasse moléculaire :486.56β-Amyloid (4-10)
CAS :Antibodies corresponding to beta-amyloid (4-10) are effective in vivo inhibitors of cytotoxicity, amyloid plaque formation and special memory disturbances inFormule :C39H52N12O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :880.9
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