Bêta-amyloïde
Les inhibiteurs de bêta-amyloïde sont des composés qui ciblent spécifiquement et inhibent la formation ou l'agrégation des peptides bêta-amyloïdes, impliqués de manière critique dans la pathogenèse de la maladie d'Alzheimer. L'accumulation de plaques bêta-amyloïdes dans le cerveau est l'un des principaux signes pathologiques de la maladie d'Alzheimer, contribuant à la dysfonction neuronale, à la perte synaptique et au déclin cognitif. En empêchant l'agrégation des bêta-amyloïdes, ces inhibiteurs font l'objet de recherches intensives comme agents thérapeutiques potentiels visant à ralentir ou même arrêter la progression de la maladie d'Alzheimer. Chez CymitQuimica, nous proposons une variété d'inhibiteurs de bêta-amyloïde de haute qualité pour soutenir vos recherches sur les troubles neurodégénératifs, l'agrégation des protéines et le développement de thérapies pour la maladie d'Alzheimer.
228 produits trouvés pour "Bêta-amyloïde"
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E3 ligase Ligand 41
CAS :E3 Ligase Ligand 41 (Compound SI-13) serves as a ligand for the E3 ubiquitin ligase DCAF16. It is designed to connect with SLF through a linker, enabling the formation of KB03-SLF.Formule :C13H12ClF3N2O4Couleur et forme :SolidMasse moléculaire :352.69FITC-β-Ala-Amyloid β-Protein (1-42) (ammonium)
FITC-β-Ala-Amyloid β-Protein (1-42) (ammonium) is a FITC-labeled amyloid beta monomer, Alzheimer’s research, drug screening, and biomolecular studies.Formule :C227H330N58O66S2Couleur et forme :SolidMasse moléculaire :4991.53β-Amyloid (13-27)
CAS :β-Amyloid (13-27) is a peptide consisting of amino acid of 13 to 27 of beta amyloid protein.Formule :C84H126N24O24Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1856.05AZD4694 Precursor
CAS :AZD4694 Precursor used for synthesizing [18F]AZD4694, a high-affinity amyloid-β imaging agent.Formule :C22H25N3O7Couleur et forme :SolidMasse moléculaire :443.45β-Amyloid (1-16)
CAS :β-Amyloid (1-16) is an amyloidogenic protein fragment with a sequence derived from β-amyloid.Formule :C84H119N27O28Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1955.04β-Amyloid (11-22)
CAS :β-Amyloid (11-22) is a peptide fragment of β-Amyloid.Beta-amyloid peptide (Abeta), the major constituent of amyloid plaques in the brains of Alzheimer’sFormule :C70H102N18O18Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1483.67Aβ-IN-7
Aβ-IN-7 (compound 5a) acts as a potent inhibitor of Aβ aggregation, stabilizing Aβ monomers at 50 μM concentration to prevent them from forming larger oligomersFormule :C14H10N2SCouleur et forme :SolidMasse moléculaire :238.31RI-OR2-TAT
CAS :RI-OR2-TAT is a brain-penetrable inhibitor targeting β-amyloid (β-Amyloid) oligomerization. It is engineered by integrating the HIV protein transduction domain TAT into RI-OR2. RI-OR2-TAT binds to Aβ42 fibrils with a Kd value of 58-125 nM. It reduces Aβ aggregation and plaque levels, diminishes microglial activation and oxidative damage, and enhances the number of young neurons in the dentate gyrus.Formule :C117H201N49O23Couleur et forme :SolidMasse moléculaire :2662.16β-Amyloid (1-43)(human) TFA
β-Amyloid (1-43)(human) TFA exhibits greater aggregation tendencies and heightened toxicity compared to its well-established counterpart, Aβ1-42.Formule :C209H319F3N56O64SCouleur et forme :SolidMasse moléculaire :4729.21GSK-3β inhibitor 27
GSK-3β inhibitor27 (Compound 1c) is a reversible, competitive inhibitor of GSK-3β with an IC50 value of 2.2 μM. It inhibits tau hyperphosphorylation and reduces Aβ protein aggregation, demonstrating metal chelation and neuroprotective potential. GSK-3β inhibitor27 is promising for research into neurodegenerative diseases, such as Alzheimer's disease.Formule :C16H17ClN4O2Couleur et forme :SolidMasse moléculaire :332.79Chemerin-9 (149-157) TFA
Chemerin-9 (149-157) TFA is a peptide located at positions 149-157 of chemerin-9, acting as a ChemR23/CMKLR1 agonist.Formule :C56H67F3N10O15Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :1177.18Anti-Amyloid β Antibody (scFv59)
Anti-Amyloid Beta Antibody (scFv59) is a human-derived antibody produced in CHO cells that targets Amyloid-β. For isotype control, please refer to Human IgG1 kappa, Isotype Control.Couleur et forme :Odour LiquidMerinetug
CAS :Merinetug is a humanized IgG1κ antibody that targets Amyloid Beta (Aβ). Its corresponding isotype control is Human IgG1 kappa, Isotype Control.Couleur et forme :LiquidCHF-5022
CAS :CHF-5022 is a nonsteroidal anti-inflammatory drug that selectively inhibits the production of beta-amyloid protein (1-42) (ABETA42).Formule :C17H12F4O2Couleur et forme :SolidMasse moléculaire :324.27Methoxy-X04
CAS :Methoxy-X04, a derivative of Congo red and Chrysamine-G, is a brain-permeable fluorescent probe for amyloid-β (Aβ).
Formule :C23H20O3Degré de pureté :98.96%Couleur et forme :SolidMasse moléculaire :344.4mcK6A1
mcK6A1 serves as an inhibitor of amyloid-β (Aβ) aggregation, selectively binding to the 16KLVFFA21 fragment of Aβ42, leading to the formation of an extended β-sheet structure and preventing the formation of Aβ42 oligomers. This compound is valuable for research into Alzheimer's disease and other amyloid-related disorders.Formule :C71H99N17O16Couleur et forme :SolidMasse moléculaire :1446.65β-Amyloid (4-10)
CAS :Antibodies corresponding to beta-amyloid (4-10) are effective in vivo inhibitors of cytotoxicity, amyloid plaque formation and special memory disturbances inFormule :C39H52N12O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :880.92,3-Dehydrosilybin A
CAS :2,3-Dehydrosilybin A is a useful organic compound for research related to life sciences and the catalog number is T125202.Formule :C25H20O10Couleur et forme :SolidMasse moléculaire :480.43β-Amyloid (10-20)
CAS :Amyloid β-Protein (10-20) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Amyloid β protein fragment containing the α-Formule :C71H99N17O16Degré de pureté :98%Couleur et forme :Lyophilized PowderMasse moléculaire :1446.655-FAM-β-Amyloid (1-28)
5-FAM-β-Amyloid (1-28) is a fluorescently-labeled peptide corresponding to the first 28 amino acids of the β-Amyloid protein.Formule :C166H219N41O52Couleur et forme :SolidMasse moléculaire :3620.76p-HTAA
CAS :Pentamer Hydrogen Thiophene Acetic Acid (p-HTAA) is a compound that specifically targets and labels amyloid-beta (Aβ) deposits in the brains of living mice [1].Formule :C24H16O4S5Couleur et forme :SolidMasse moléculaire :528.71β-Amyloid (1-17)
CAS :This synthetic peptide consists of amino acids 1 to 17 of beta amyloid protein. This peptide can be employed in beta amyloid solubility studies.Formule :C90H130N28O29Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2068.2RAGE antagonist peptide
CAS :RAGE antagonist blocks S100P/A4, HMGB-1; hinders glioma growth, metastasis; reduces PDAC cell growth, NF-κB activity; counters TDI effects in mice.Formule :C57H101N13O17SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1272.56(Met(O)35)-Amyloid β-Protein (1-42)
(Met(O)35)-Amyloid β-Protein (1-42) represents the oxidized form of Methionine 35 in Aβ42, capable of producing an oligomer size distribution akin to that ofFormule :C203H311N55O61SCouleur et forme :SolidMasse moléculaire :4530.04β-Amyloid Protein Precursor 770 (135-155)
CAS :Beta-Amyloid Protein Precursor 770 (135-155)Aβ Protein Precursor 770 (135-155)
Formule :C116H172N35O31S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2617.96β-Amyloid (10-35), amide
CAS :β-Amyloid (10-35), amide, is a chemical compound consisting of 26 amino acids, specifically residues 10-35 of the Aβ peptide.Formule :C133H205N35O36SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :2902.33β-Amyloid (1-28)
CAS :β-Amyloid (1-28) is a β-Amyloid protein fragment involved in metal binding.Formule :C145H209N41O46Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3262.51Amyloid-Forming peptide GNNQQNY
CAS :Amyloid-Forming peptide GNNQQNY, a biologically active heptapeptide derived from the N-terminal prion-determining domain of yeast Sup35, is instrumental inFormule :C33H48N12O14Couleur et forme :SolidMasse moléculaire :836.81Sabirnetug
CAS :Sabirnetug is a humanized IgG2κ monoclonal antibody that specifically targets the amyloid-β (A4) precursor protein.Couleur et forme :LiquidSQ-3
SQ-3, a quinoline analogue, prefers α-syn (Ki=39.3nM) to Aβ (Ki=230nM), and [18F]SQ3 is a lead for α-syn probes. [1]Formule :C21H21FN2OCouleur et forme :SolidMasse moléculaire :336.4Davunetide
CAS :Davunetide: neuroprotective 8-amino acid peptide, improves daily function in schizophrenia, boosts memory in mild cognitive impairment.Formule :C36H60N10O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :824.92BIBD-124
CAS :BIBD-124, with an IC50 value of 9.51 nM, effectively binds to amyloid beta (Aβ) plaques.Formule :C19H24FN3O3Couleur et forme :SolidMasse moléculaire :361.41Aβ-IN-8
Aβ-IN-8, also known as compound 7e, is a potent inhibitor of Aβ aggregation [1].Formule :C22H16F3N3O3SCouleur et forme :SolidMasse moléculaire :459.44β-Amyloid (1-34)
CAS :This is a fragment of beta-amyloid peptide. It has amino acids 1 through 34.Formule :C170H253N47O52Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3787.2(D-Asp1)-Amyloid β-Protein (1-42)
CAS :(D-Asp1)-Amyloid β-Protein (1-42), a peptide fragment of amyloid β-protein (Aβ), serves as the primary constituent of vascular and parenchymal amyloid depositsFormule :C203H311N55O60SCouleur et forme :SolidMasse moléculaire :4514.04Acetyl-Tau Peptide (273-284) amide
CAS :Acetyl-Tau Peptide (273-284) amide inhibits Ac-Aβ(25–35)-NH2 aggregation and models Aβ/Tau interaction.Formule :C64H116N18O17Couleur et forme :SolidMasse moléculaire :1409.72Biotinoyl tripeptide-1
CAS :Biotinoyl tripeptide-1 can produce hair follicles by promoting scalp micro-circulation and reduce follicle atrophy and aging.Formule :C24H38N8O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :566.67β-Amyloid (12-20)
CAS :β-Amyloid (12-20) is a peptide fragment of β-Amyloid.Thsis peptide contain the amino acid residues VFF at position (18-20), suggesting that this triad hasFormule :C57H83N15O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1154.36β-Amyloid (35-42)
CAS :β-Amyloid (35-42) is a peptide derived from the beta-amyloid protein, encompassing amino acids 35 through 42.Formule :C33H60N8O9SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :744.94Aducanumab
CAS :Aducanumab (BIIB037) is an IgG1 antibody targeting amyloid beta to treat Alzheimer's; it's brain-permeable.
Degré de pureté :95% - 97.10%Couleur et forme :LiquidMasse moléculaire :145.93 kDaβ-Amyloid (22-35)
CAS :β-Amyloid (22-35) is a 14-aa peptide, shows aggregates and induces neurotoxicity in the hippocampal cells.Formule :C59H102N16O21SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1403.62Biotin-β-Amyloid (1-42), human TFA
Biotin-β-Amyloid (1-42), human TFA, also known as Biotin-Amyloid β-Peptide (1-42) (human) TFA, is a biotin-labeled 42-amino acid peptide implicated in theFormule :C215H326F3N57O64S2Couleur et forme :SolidMasse moléculaire :4854.36β-Amyloid (1-9)
CAS :This is an N-terminal fragment of beta amyloid.Formule :C42H60N14O17Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1033.01β-Amyloid (29-40)
CAS :β-Amyloid (29-40) is a fragment of Amyloid-β peptide.Alzheimer's beta amyloid peptide (29-40/42) C-terminal fragments have physical and chemical propertiesFormule :C49H88N12O13SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1085.36β-Amyloid (25-35) acetate
β-Amyloid (25-35) acetate is the Aβ(25-35) fragment of amyloid beta peptide, neurotoxicity, construct Alzheimer's disease cell and animal models.Degré de pureté :98.26%β-Amyloid (22-40)
CAS :This synthetic peptide consists of amino acids 22 to 40 of beta amyloid protein.Formule :C78H135N21O26SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1815.1(Glu20)-Amyloid β-Protein (1-42)
CAS :(Glu20)-Amyloid β-Protein (1-42) represents a variant of amyloid β-protein (Aβ) that fibrillizes more slowly.Formule :C199H309N55O62SCouleur et forme :SolidMasse moléculaire :4495.98β-Amyloid (18-28)
CAS :Intracerebroventricular administration of synthetic peptides Beta-amyloid (12-20), (12-28), and (18-28) causes amnesia in mice.Formule :C55H81N13O18Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1212.31β-Amyloid (1-11)
CAS :Anionic interaction of Beta-amyloid (1-11) with Factor XII is suspected to cause massive activation of the C4 (complement 4) system in the cerebrospinal fluidFormule :C56H76N16O22Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1325.3Guluronic acid
CAS :Guluronic acid (G2013) is in hyaluronic acid; a nonsteroidal anti-inflammatory with benefits.Formule :C6H10O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :194.139
