Bêta-amyloïde
Les inhibiteurs de bêta-amyloïde sont des composés qui ciblent spécifiquement et inhibent la formation ou l'agrégation des peptides bêta-amyloïdes, impliqués de manière critique dans la pathogenèse de la maladie d'Alzheimer. L'accumulation de plaques bêta-amyloïdes dans le cerveau est l'un des principaux signes pathologiques de la maladie d'Alzheimer, contribuant à la dysfonction neuronale, à la perte synaptique et au déclin cognitif. En empêchant l'agrégation des bêta-amyloïdes, ces inhibiteurs font l'objet de recherches intensives comme agents thérapeutiques potentiels visant à ralentir ou même arrêter la progression de la maladie d'Alzheimer. Chez CymitQuimica, nous proposons une variété d'inhibiteurs de bêta-amyloïde de haute qualité pour soutenir vos recherches sur les troubles neurodégénératifs, l'agrégation des protéines et le développement de thérapies pour la maladie d'Alzheimer.
205 produits trouvés pour "Bêta-amyloïde"
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Biotin-β-Amyloid (1-42), human TFA
<p>Biotin-β-Amyloid (1-42), human TFA, also known as Biotin-Amyloid β-Peptide (1-42) (human) TFA, is a biotin-labeled 42-amino acid peptide implicated in the</p>Formule :C215H326F3N57O64S2Couleur et forme :SolidMasse moléculaire :4854.36β-Amyloid (29-40)
CAS :<p>β-Amyloid (29-40) is a fragment of Amyloid-β peptide.Alzheimer's beta amyloid peptide (29-40/42) C-terminal fragments have physical and chemical properties</p>Formule :C49H88N12O13SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1085.36AChE/Aβ-IN-6
<p>BACE1-IN-15 (compound 4j) serves as an effective inhibitor of BACE1 (β-secretase), efficiently mitigating the copper-induced toxicity of Aβ, with an EC50 value of 0.68 μM.</p>Couleur et forme :Odour Solid(Met(O2)35)-Amyloid β-Protein (1-42)
<p>(Met(O2)35)-Amyloid β-Protein (1-42) is a peptide [1] .</p>Formule :C203H311N55O62SCouleur et forme :SolidMasse moléculaire :4546.04(Glu20)-Amyloid β-Protein (1-42)
CAS :<p>(Glu20)-Amyloid β-Protein (1-42) represents a variant of amyloid β-protein (Aβ) that fibrillizes more slowly.</p>Formule :C199H309N55O62SCouleur et forme :SolidMasse moléculaire :4495.98DDC 2′,3′-O-disulfate
<p>DDC 2′,3′-O-disulfate (compound 4) inhibits the fibrillization and oligomerization of Aβ42, showing promise for Alzheimer's disease (AD) research [1].</p>Formule :C17H16O11S2Couleur et forme :SolidMasse moléculaire :460.43β-Amyloid (22-40)
CAS :<p>This synthetic peptide consists of amino acids 22 to 40 of beta amyloid protein.</p>Formule :C78H135N21O26SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1815.1Amyloid β-Protein (3-42)
CAS :<p>Amyloid β-Protein (3-42), the precursor of Pyr peptide, serves as the foundation of the amyloid template block in Alzheimer's disease when modified to</p>Couleur et forme :SolidAducanumab
CAS :<p>Aducanumab (BIIB037) is an IgG1 antibody targeting amyloid beta to treat Alzheimer's; it's brain-permeable.</p>Degré de pureté :95% - 97.10%Couleur et forme :LiquidMasse moléculaire :145.93 kDaβ-Amyloid (13-27)
CAS :<p>β-Amyloid (13-27) is a peptide consisting of amino acid of 13 to 27 of beta amyloid protein.</p>Formule :C84H126N24O24Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1856.057-Deoxy-trans-dihydronarciclasine
CAS :<p>7-Deoxy-trans-dihydronarciclasine is an alkaloid that functions as a tobacco mosaic virus (TMV) inhibitor with an IC50 of 1.80 μM and also serves as an anti-</p>Formule :C14H15NO6Couleur et forme :SolidMasse moléculaire :293.27β-Amyloid (11-22)
CAS :<p>β-Amyloid (11-22) is a peptide fragment of β-Amyloid.Beta-amyloid peptide (Abeta), the major constituent of amyloid plaques in the brains of Alzheimer’s</p>Formule :C70H102N18O18Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1483.67p-HTAA
CAS :<p>Pentamer Hydrogen Thiophene Acetic Acid (p-HTAA) is a compound that specifically targets and labels amyloid-beta (Aβ) deposits in the brains of living mice [1].</p>Formule :C24H16O4S5Couleur et forme :SolidMasse moléculaire :528.71mcK6A1
<p>mcK6A1 serves as an inhibitor of amyloid-β (Aβ) aggregation, selectively binding to the 16KLVFFA21 fragment of Aβ42, leading to the formation of an extended β-sheet structure and preventing the formation of Aβ42 oligomers. This compound is valuable for research into Alzheimer's disease and other amyloid-related disorders.</p>Formule :C71H99N17O16Couleur et forme :SolidMasse moléculaire :1446.65Biotinoyl tripeptide-1
CAS :<p>Biotinoyl tripeptide-1 can produce hair follicles by promoting scalp micro-circulation and reduce follicle atrophy and aging.</p>Formule :C24H38N8O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :566.67β-Amyloid (1-16)
CAS :<p>β-Amyloid (1-16) is an amyloidogenic protein fragment with a sequence derived from β-amyloid.</p>Formule :C84H119N27O28Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1955.04β-Amyloid (33-40)
CAS :<p>β-Amyloid (33-40) is a peptide comprising amino acids 33 to 40 of the beta-amyloid protein.</p>Formule :C32H58N8O9SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :730.92AC 253
CAS :<p>Amylin (AMY3) receptor antagonist; blocks cAMP, Ca2+, PKA, MAPK, Akt, and cFOS activity; prevents Aβ-induced neuronal death. Cyclic AC 253 variant exists.</p>Formule :C122H196N40O39Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2847.11Acetyl-Tau Peptide (273-284) amide
CAS :<p>Acetyl-Tau Peptide (273-284) amide inhibits Ac-Aβ(25–35)-NH2 aggregation and models Aβ/Tau interaction.</p>Formule :C64H116N18O17Couleur et forme :SolidMasse moléculaire :1409.72β-Amyloid (1-9)
CAS :<p>This is an N-terminal fragment of beta amyloid.</p>Formule :C42H60N14O17Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1033.01Chemerin-9 (149-157) TFA
<p>Chemerin-9 (149-157) TFA is a peptide located at positions 149-157 of chemerin-9, acting as a ChemR23/CMKLR1 agonist.</p>Formule :C56H67F3N10O15Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :1177.18CHF-5022
CAS :<p>CHF-5022 is a nonsteroidal anti-inflammatory drug that selectively inhibits the production of beta-amyloid protein (1-42) (ABETA42).</p>Formule :C17H12F4O2Couleur et forme :SolidMasse moléculaire :324.27β-Amyloid Protein Precursor 770 (135-155)
CAS :<p>Beta-Amyloid Protein Precursor 770 (135-155)Aβ Protein Precursor 770 (135-155)</p>Formule :C116H172N35O31S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2617.962,3-Dehydrosilybin A
CAS :<p>2,3-Dehydrosilybin A is a useful organic compound for research related to life sciences and the catalog number is T125202.</p>Formule :C25H20O10Couleur et forme :SolidMasse moléculaire :480.425GSK-3β inhibitor 27
<p>GSK-3β inhibitor27 (Compound 1c) is a reversible, competitive inhibitor of GSK-3β with an IC50 value of 2.2 μM. It inhibits tau hyperphosphorylation and reduces Aβ protein aggregation, demonstrating metal chelation and neuroprotective potential. GSK-3β inhibitor27 is promising for research into neurodegenerative diseases, such as Alzheimer's disease.</p>Formule :C16H17ClN4O2Couleur et forme :SolidMasse moléculaire :332.79Anti-Amyloid β Antibody (scFv59)
<p>Anti-Amyloid Beta Antibody (scFv59) is a human-derived antibody produced in CHO cells that targets Amyloid-β. For isotype control, please refer to Human IgG1 kappa, Isotype Control.</p>Couleur et forme :Odour Liquid5-FAM-β-Amyloid (1-28)
<p>5-FAM-β-Amyloid (1-28) is a fluorescently-labeled peptide corresponding to the first 28 amino acids of the β-Amyloid protein.</p>Formule :C166H219N41O52Couleur et forme :SolidMasse moléculaire :3620.76β-Amyloid (1-17)
CAS :<p>This synthetic peptide consists of amino acids 1 to 17 of beta amyloid protein. This peptide can be employed in beta amyloid solubility studies.</p>Formule :C90H130N28O29Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2068.2δ-secretase inhibitor 11
CAS :<p>δ-secretase inhibitor 11 is an inhibitor of δ-secretase and can be used as a lead compound for translational development of AD treatment.</p>Formule :C10H12N4O2Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :220.231H-Indole-3-carboxylic acid, 5-[2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]propoxy]-2-methyl-1-(4-methylphenyl)-, ethyl ester
CAS :<p>Compound 5936-0108对β-淀粉样蛋白可能具有调节作用。</p>Formule :C26H34N2O7Degré de pureté :99.44%Couleur et forme :SoildMasse moléculaire :486.56β-Amyloid (12-28)
CAS :<p>Amyloid β-peptide fragment; minimum section required to bind to brain proteins.</p>Formule :C89H135N25O25Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1955.18AZD4694 Precursor
CAS :<p>AZD4694 Precursor used for synthesizing [18F]AZD4694, a high-affinity amyloid-β imaging agent.</p>Formule :C22H25N3O7Couleur et forme :SolidMasse moléculaire :443.45RAGE antagonist peptide
CAS :<p>RAGE antagonist blocks S100P/A4, HMGB-1; hinders glioma growth, metastasis; reduces PDAC cell growth, NF-κB activity; counters TDI effects in mice.</p>Formule :C57H101N13O17SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1272.56β-Amyloid (18-28)
CAS :<p>Intracerebroventricular administration of synthetic peptides Beta-amyloid (12-20), (12-28), and (18-28) causes amnesia in mice.</p>Formule :C55H81N13O18Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1212.31β-Amyloid (10-20)
CAS :<p>Amyloid β-Protein (10-20) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Amyloid β protein fragment containing the α-</p>Formule :C71H99N17O16Degré de pureté :98%Couleur et forme :Lyophilized PowderMasse moléculaire :1446.65Sabirnetug
CAS :<p>Sabirnetug is a humanized IgG2κ monoclonal antibody that specifically targets the amyloid-β (A4) precursor protein.</p>Couleur et forme :Liquidγ-Secretase Modulators
CAS :<p>gamma-Secretase Modulators serves as a useful treatment for Alzheimer's disease by inhibiting the production of Amyloid-β.</p>Formule :C26H24F3N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :483.48Davunetide
CAS :<p>Davunetide: neuroprotective 8-amino acid peptide, improves daily function in schizophrenia, boosts memory in mild cognitive impairment.</p>Formule :C36H60N10O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :824.92BIBD-124
CAS :<p>BIBD-124, with an IC50 value of 9.51 nM, effectively binds to amyloid beta (Aβ) plaques.</p>Formule :C19H24FN3O3Couleur et forme :SolidMasse moléculaire :361.41SEN177
CAS :<p>SEN177 shows the potential in the research of Huntington's disease that is a potent inhibitor of glutaminyl cyclase (QPCT) with an IC 50 of 0.013μM for glutaminyl-peptide cyclotransferase-like (QPCTL). The Ki value of SEN177 for human glutaminyl cyclase (hQC) is 20 nM. SEN177 significantly reduces the early stages of mutant HTT oligomerisation and reduces the percentage of neurons with Q80 aggregates [1].</p>Formule :C18H19FN6Couleur et forme :SolidMasse moléculaire :338.38TH-237A
CAS :<p>TH-237A is a novel neuroprotective agent exhibiting favorable permeation across the blood-brain barrier.</p>Formule :C18H17F2NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :333.335Begacestat
CAS :Begacestat (GSI-953) is a potent and selective gamma-secretase inhibitor that inhibits Amyloid-beta, inhibits cleavage of APP,,Alzheimer's disease.Formule :C9H8ClF6NO3S2Couleur et forme :SolidMasse moléculaire :391.74(Rac)-Z-Phe-Phe-FMK
CAS :<p>(Rac)-Z-Phe-Phe-FMK (Cathepsin L-IN-2) is a cathepsin L inhibitor that inhibits the tendency of β-amyloid to induce apoptotic changes .</p>Formule :C27H27FN2O4Degré de pureté :98.27%Couleur et forme :SolidMasse moléculaire :462.51AZD4694
CAS :<p>Flutafuranol (AZD4694/NAV4694) binds beta-amyloid, potential PET tracer for Alzheimer's. Non-F18 version supplied.</p>Formule :C14H11FN2O2Couleur et forme :SolidMasse moléculaire :258.25Cu(II)GTSM
CAS :<p>Cu(II)GTSM is a cell permeable copper complex inhibits GSK3β activity and suppresses levels of neurotoxic amyloid β-trimers and phosphorylated tau.</p>Formule :C6H10CuN6S2Degré de pureté :99.21%Couleur et forme :SolidMasse moléculaire :293.86Pyridoxal 5'-phosphate hydrate
CAS :<p>Pyridoxal 5'-phosphate hydrate (PLP)(1:x), the active form of vitamin B6, is a cofactor for many different enzymes involved in transamination reactions,</p>Formule :C8H10NO6PDegré de pureté :97.52%Couleur et forme :SolidMasse moléculaire :247.141,1'-Methylenedi-2-naphthol
CAS :<p>1,1'-Methylenedi-2-naphthol target CYP2C19 - cytochrome P450 family 2 subfamily C member 19 (human).</p>Formule :C21H16O2Degré de pureté :98.91%Couleur et forme :Light Pink To Light Brown Crystalline PowderMasse moléculaire :300.35Miridesap
CAS :<p>Miridesap (GSK2315698) rapidly depletes SAP in blood, cerebrospinal fluid, and amyloid deposits via liver clearance.</p>Formule :C16H24N2O6Degré de pureté :≥95%Couleur et forme :SolidMasse moléculaire :340.37PiB
CAS :<p>PiB (Pittsburgh Compound-B) is a standard for analysis of 11C-PiB. 11C-PiB is a β-amyloid PET imaging tracer for Alzheimer's disease diagnosis.</p>Formule :C14H12N2OSDegré de pureté :97.02%Couleur et forme :SolidMasse moléculaire :256.32CRANAD 2
CAS :<p>CRANAD-2, a near-infrared probe, detects amyloid-beta in vivo, increasing fluorescence 70x and shifting blue 90 nm upon binding.</p>Formule :C23H25BF2N2O2Degré de pureté :99.44%Couleur et forme :Dark Blue To Black PowderMasse moléculaire :410.27
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