COX
Les inhibiteurs de la cyclooxygénase (COX) sont des composés qui bloquent l'activité des enzymes COX, impliquées dans la production de prostaglandines, des médiateurs clés de l'inflammation et de la douleur. En neurosciences, les inhibiteurs de la COX sont étudiés pour leur potentiel à réduire la neuroinflammation, qui est impliquée dans diverses maladies neurodégénératives telles que la maladie d'Alzheimer, la maladie de Parkinson et la sclérose en plaques. En inhibant la COX, ces composés peuvent aider à atténuer les processus inflammatoires dans le cerveau et à protéger contre les lésions neuronales. Chez CymitQuimica, nous fournissons une gamme d'inhibiteurs de la COX pour soutenir vos recherches sur la neuroinflammation, la gestion de la douleur et les maladies neurodégénératives.
562 produits trouvés pour "COX"
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Deracoxib
CAS :<p>Deracoxib (SC 46) is a selective COX-2 inhibitor, non-steroidal, non-narcotic anti-inflammatory drug with an IC50 of 70-150 μM for osteosarcoma cells.</p>Formule :C17H14F3N3O3SDegré de pureté :98.94% - 99.81%Couleur et forme :SolidMasse moléculaire :397.37Acetylsalicylic Acid
CAS :Formule :C9H8O4Degré de pureté :95%Couleur et forme :SolidMasse moléculaire :180.1574Guaiacol
CAS :<p>Guaiacol, a flavorant precursor, has medicinal uses and serves as an oxygen indicator turning yellow-brown at 470 nm.</p>Formule :C7H8O2Degré de pureté :99.95%Couleur et forme :Colourless To Pale Yellow Solid CrystallineMasse moléculaire :124.14Ketorolac tromethamine salt
CAS :Formule :C19H24N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :376.4037Metamizole sodium hydrate
CAS :<p>Metamizole sodium hydrate (Analgin) is a potent analgesic drug that has been demonstrated to inhibit cyclooxygenase (COX).</p>Formule :C13H18N3NaO5SDegré de pureté :99.69% - 99.89%Couleur et forme :White Or Light Yellow Crystalline Powder Odorless Tiny BitterMasse moléculaire :351.36(R)-Naproxen
CAS :<p>(R)-Naproxen: anti-inflammatory with antipyretic and analgesic effects; treats gout, dysmenorrhea, rheumatoid arthritis.</p>Formule :C14H14O3Degré de pureté :99.62% - 99.94%Couleur et forme :SolidMasse moléculaire :230.262,3'-Bipyridine, 5-chloro-6'-methyl-3-[4-(methylsulfonyl)phenyl]-
CAS :Formule :C18H15ClN2O2SDegré de pureté :99%Couleur et forme :SolidMasse moléculaire :358.8419Ref: IN-DA002878
1g28,00€5g69,00€10g128,00€15gÀ demander1kgÀ demander25g155,00€50gÀ demander75gÀ demander100g528,00€500gÀ demanderCatechin
CAS :<p>Catechin (Cianidanol) is a flavan-3-ol, a type of natural phenol and antioxidant.</p>Formule :C15H14O6Degré de pureté :97.34% - 99.82%Couleur et forme :SolidMasse moléculaire :290.27Tebufelone
CAS :<p>Tebufelone is a potent NSAID, inhibits CO, has anti-inflammatory and analgesic properties, and blocks lipoxygenase products (IC50 ~20-22 microM).</p>Formule :C20H28O2Degré de pureté :99.32%Couleur et forme :SolidMasse moléculaire :300.442-O-Sinapoyl makisterone A
<p>Compound 2, formally known as 2-O-Sinapoyl makisterone A, is a sinapinic acid-ecdysterone hybrid that acts as a selective inhibitor of COX-2, effectively</p>Formule :C39H56O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :700.8615-LOX-IN-2
<p>15-LOX-IN-2 (Compound 2a) is an orally active inhibitor of COX-2/15-LOX and a partial agonist of PPARγ. It exhibits anti-inflammatory activity by inhibiting levels of 20-HETE, IL-1β, and TNF-α in LPS-treated RAW 264.7 cells. Additionally, it significantly enhances glucose uptake without the presence of insulin and is applicable in metabolic disease research.</p>Couleur et forme :Odour SolidCOX-1/2-IN-5
<p>COX-1/2-IN-5 (compound 2a) functions as a dual inhibitor of COX1/2, demonstrating inhibitory concentrations (IC50) of 2.650 μM and 0.958 μM, respectively, and</p>Formule :C21H22N2O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :414.474-ACETAMIDOANTIPYRINE
CAS :<p>4-ACETAMIDOANTIPYRINE, with CAS No. 83-15-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-ACETAMIDOANTIPYRINE provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Formule :C13H15N3O2Couleur et forme :SolidMasse moléculaire :245.28COX-2-IN-33
<p>COX-2-IN-33 (compound 5f) is a selective COX-2 inhibitor with an IC50 value of 45.5 nM and exhibits potential as an anti-inflammatory agent.</p>Formule :C20H13ClF3N5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :479.8Pemedolac
CAS :<p>Pemedolac (Dexpemedolac) is a small molecule COX inhibitor used to treat neurological disorders, skin and musculoskeletal disorders.</p>Formule :C22H23NO3Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :349.42NF157
CAS :<p>NF157, a selective P2Y11 antagonist with pKi 7.35, lowers MMP-3/MMP-13, aiding OA treatment; IC50s: P2Y11 463 nM, P2Y1 1811 μM, P2Y2 170 μM.</p>Formule :C49H28F2N6Na6O23S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1437.1COX-1/2-IN-4
<p>COX-1/2-IN-4 (compound 2b) is a dual COX-1 and COX-2 inhibitor with respective IC50 values of 0.239 μM for COX-1 and 0.191 μM for COX-2.</p>Formule :C22H24N2O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :380.5Ketoprofen lysine salt
CAS :<p>Ketoprofen lysine salt is a lysine salt of ketoprofen, a Non-Steroidal Anti-Inflammatory Drug</p>Formule :C22H28N2O5Couleur et forme :SolidMasse moléculaire :400.48SARS-CoV-2 Mpro-IN-41
<p>SARS-CoV-2 Mpro-IN-41 (Compound 7e) is an orally active inhibitor targeting COX-2 and SARS-CoV-2 Mpro, with respective IC50 values of 9.66 μM and 13.24 μM. It also demonstrates inhibitory activity against COX-1 (IC50: 46.11 μM). This compound significantly suppresses the expression of inflammation-related cytokines such as TNF-α, IL-6, and IL-1β, exhibiting anti-inflammatory properties. By selectively inhibiting COX-2 and SARS-CoV-2 Mpro, SARS-CoV-2 Mpro-IN-41 exerts both anti-inflammatory and antiviral effects, making it a potential candidate for research in inflammation and COVID-19 treatment.</p>Formule :C27H23ClN4O3SCouleur et forme :SolidMasse moléculaire :518.11794Anti-inflammatory agent 53
<p>Anti-inflammatory agent 52 (compound 7c) is an orally active, selective COX-2 inhibitor with demonstrated anti-HT29 metastatic activity, causing periodic arrest</p>Formule :C24H22N2O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :434.51
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