CaMK
Les inhibiteurs de la protéine kinase dépendante du calcium/calmoduline (CaMK) sont des composés spécialisés qui inhibent l'activité de la CaMK, une kinase essentielle impliquée dans une gamme de processus cellulaires, en particulier dans le système nerveux. La CaMK est cruciale pour traduire les signaux calciques en diverses réponses cellulaires, y compris la plasticité synaptique, la formation de la mémoire et l'expression génique. La dysrégulation de l'activité de la CaMK est liée à plusieurs troubles neurologiques, ce qui rend ces inhibiteurs précieux pour l'étude de la signalisation synaptique, de l'apprentissage et de la mémoire. Chez CymitQuimica, nous fournissons des inhibiteurs de CaMK de haute qualité pour soutenir vos recherches sur la plasticité synaptique, la fonction cognitive et la neuropharmacologie.
73 produits trouvés pour "CaMK"
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CALP2 TFA
CALP2 TFA, a CaM antagonist with 7.9 µM Kd, blocks CaM-dependent enzymes, boosts Ca2+ levels, and activates macrophages.Formule :C70H105F3N14O15SCouleur et forme :SolidMasse moléculaire :1471.72Calmodulin-Dependent Protein Kinase II 290-309 acetate
Calmodulin-Dependent Protein Kinase II 290-309 acetate is an effective antagonist of Ca2+/calmodulin-dependent protein kinase II (IC50 = 52 nM).Formule :C105H189N31O26SDegré de pureté :96.7%Couleur et forme :SolidMasse moléculaire :2333.88Calmodulin Binding Peptide 1
CAS :Calmodulin Binding Peptide 1, a high-affinity MLCK-derived inhibitor, blocks IP3-induced Ca2+ release.Formule :C231H373N69O70S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :5301.1MLCK Peptide
CAS :MLCK Peptide, a high-affinity (pM), fully reversible CaM-binding peptide, is derived from smooth muscle myosin light-chain kinase [1].Formule :C91H156N36O20Couleur et forme :SolidMasse moléculaire :2074.44Purine riboside triphosphate
CAS :Purine riboside triphosphate resembles adenosine; inhibits cancer cell growth by blocking RNA/DNA synthesis.Formule :C10H15N4O13P3Couleur et forme :SolidMasse moléculaire :492.17Purine riboside-5'-O-triphosphate sodium
CAS :Purine riboside-5'-O-triphosphate sodium is an active metabolite of Nebularine (HY-103694) and acts as an inhibitor of DNA primase ATP and GTP polymerization activities, with IC50 values of 35 µM and 28 µM, respectively. It also inhibits calmodulin-dependent protein kinase II (CaMKII), with a Ki value of 590 µM.Formule :C10H11N4Na4O13P3Masse moléculaire :580.09RA306
RA306 is an orally active CAMK2 inhibitor that effectively disrupts the PEAK1/CAMK2 signaling pathway. It demonstrates anti-tumor activity by inhibiting proliferation, migration, and invasion of breast cancer cells. Additionally, RA306 shows potential in cardiac disease research, as it improves dilated cardiomyopathy in mice.Couleur et forme :Odour SolidCAMKIV Protein, Human, Recombinant (GST)
CAMKIV Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag.Couleur et forme :Lyophilized PowderMasse moléculaire :79 kDa (predicted); 100 kDa (reducing conditions)KN-62
CAS :KN-62 is a potent and specific Ca2+/calmodulin-dependent protein kinase II (CaMKII) inhibitor with Ki of 0.9 μM.Formule :C38H35N5O6S2Degré de pureté :99.80% - >99.99%Couleur et forme :White SolidMasse moléculaire :721.84Ref: TM-T2694
1mg34,00€2mg49,00€5mg71,00€10mg105,00€25mg207,00€50mg404,00€100mg592,00€1mL*10mM (DMSO)105,00€CALP2 acetate(261969-04-4 free base)
CALP2 acetate is an antagonist of calmodulin showing high affinity for binding to the CaM EF-hand/Ca2+-binding site with a Kd of 7.9 µM.Formule :C68H104N14O13SDegré de pureté :97.43%Couleur et forme :SolidMasse moléculaire :1357.7Syntide 2 acetate(108334-68-5 free base)
Syntide-2 acetate is a synthetic peptide recognized as a substrate by Ca2+/calmodulin-dependent protein kinase II (CaMKII; Km = 12 μM).Formule :C70H126N20O20Degré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :1567.85Autocamtide-2-related inhibitory peptide
CAS :Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM.Formule :C64H116N22O19Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :1497.74Autocamtide 2 TFA(129198-88-5 free base)
Autocamtide 2 TFA, selective CaMKII peptide substrate, used in its activity assay.Formule :C67H119F3N22O22Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1641.79CaMKP Inhibitor
CAS :<p>CaMKP Inhibitor can inhibit CaMKP.</p>Formule :C10H8NNaO7S2Degré de pureté :96.55% - 99.98%Couleur et forme :SolidMasse moléculaire :341.28GSK3i XIII
CAS :GSK3i XIII (GSK3 inhibitor XIII) is a GSK-3 ATP-binding site inhibitor.Formule :C18H19N5Degré de pureté :98.87%Couleur et forme :SolidMasse moléculaire :305.38Ref: TM-T24111
1mg66,00€5mg120,00€10mg175,00€25mg295,00€50mg429,00€100mg605,00€1mL*10mM (DMSO)135,00€IGS-1.76
CAS :IGS-1.76 binds strongly to hNCS-1, modulates its Ric8a interaction, and inhibits the hNCS-1/Ric8a complex.Formule :C22H18N2OSDegré de pureté :98.18% - 98.56%Couleur et forme :SolidMasse moléculaire :358.46KN-92
CAS :KN-92 is an inactive analog of the CaM kinase II inhibitor KN 93.Formule :C24H25ClN2O3SCouleur et forme :SolidMasse moléculaire :456.98KN-93
CAS :KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase.Formule :C26H29ClN2O4SDegré de pureté :99.56% - 99.86%Couleur et forme :White SolidMasse moléculaire :501.04Ref: TM-T2697
1mg57,00€2mg79,00€5mg113,00€10mg155,00€25mg305,00€50mg378,00€100mg552,00€1mL*10mM (DMSO)127,00€Trifluoperazine
CAS :Trifluoperazine (trifluoroperazine) is a Dopamine D2 receptor inhibitor(IC50 : 1.2 nM), and Treatment of schizophrenia.Formule :C21H24F3N3SDegré de pureté :98.3% - 99.46%Couleur et forme :White To Yellowish Crystalline PowderMasse moléculaire :407.5NH125
CAS :NH125 is a selective eEF-2 kinase inhibitor with IC50 of 60 nM, >125-fold selectivity over PKC, PKA, and CaMKII, and also a potent histidine kinase inhibitor.Formule :C27H45IN2Degré de pureté :98.60%Couleur et forme :SolidMasse moléculaire :524.56Ref: TM-T6605
1mg40,00€2mg52,00€5mg88,00€10mg119,00€25mg264,00€50mg454,00€100mg655,00€1mL*10mM (DMSO)87,00€
