GluR
Les inhibiteurs des récepteurs du glutamate sont des composés qui bloquent l'activité des récepteurs du glutamate, les principaux récepteurs des neurotransmetteurs excitateurs dans le cerveau. Ces récepteurs jouent un rôle crucial dans la transmission synaptique, la plasticité, l'apprentissage et la mémoire. La dérégulation de la signalisation du glutamate est associée à divers troubles neurologiques, tels que l'épilepsie, les accidents vasculaires cérébraux et les maladies neurodégénératives. Les inhibiteurs des récepteurs du glutamate sont essentiels pour étudier les mécanismes de l'excitotoxicité et développer des stratégies neuroprotectrices. Chez CymitQuimica, nous offrons une gamme d'inhibiteurs des récepteurs du glutamate pour soutenir vos recherches sur la fonction synaptique, la neuroprotection et les troubles cognitifs.
255 produits trouvés pour "GluR"
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Org-26576
CAS :<p>Org-26576 is a positive allosteric modulator of the AMPA receptor.</p>Formule :C11H12N2O2Degré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :204.23AZD-8529 mesylate
CAS :<p>AZD-8529 mesylate is a highly selective, and orally bioavailable positive allosteric modulator of mGluR2 (EC50: 285 nM).</p>Formule :C25H28F3N5O6SDegré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :583.58DHPG
CAS :<p>DHPG is a potent Group I mGluR agonist; doesn't affect Group II/III; linked to phospholipase D.</p>Formule :C8H9NO4Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :183.16NBQX disodium
CAS :<p>NBQX Disodium (FG9202 disodium) is a highly selective, competitive AMPA receptor antagonist with neuroprotective and anticonvulsant activity.</p>Formule :C12H6N4Na2O6SDegré de pureté :97.6% - 98.22%Couleur et forme :SolidMasse moléculaire :380.2415LY339434 HCl
<p>LY339434 HCl is a low affinity GluR5 erythrocyte receptor agonist.LY339434 HCl causes rapid neuronal death primarily by affecting N-methyl-D-aspartate (NMDA)</p>Formule :C18H20ClNO4Degré de pureté :97.96% - 99.68%Couleur et forme :SoildMasse moléculaire :349.81Decoglurant
CAS :<p>Decoglurant (RO4995819) is a negative allosteric modulator of mGluR2 and mGluR3 and it also is developed as an antidepressant.</p>Formule :C21H11F6N5Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :447.34Piracetam
CAS :<p>Piracetam (UCB-6215), a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), is used in therapy of the extensive cognitive disorders.</p>Formule :C6H10N2O2Degré de pureté :97.16%Couleur et forme :Crystals From Isopropanol SolidMasse moléculaire :142.16(R)-3,4-DCPG HCl
<p>(R)-3,4-DCPG HCl is a potent and selective mGlu8a receptor agonist that activates metabotropic glutamate receptors on primary afferent terminals in the neonatal</p>Formule :C10H10ClNO6Degré de pureté :98.80% - 99.89%Couleur et forme :SoildMasse moléculaire :275.64VU0650786
CAS :<p>VU0650786: selective mGlu3 NAM, CNS-penetrant, IC50 392 nM, shows antidepressant/anxiolytic effects in rodents.</p>Formule :C18H15ClFN5O2Degré de pureté :99.09%Couleur et forme :SolidMasse moléculaire :387.8KM02894
CAS :<p>KM02894 inhibits glutamate release, potentially reducing cancer-induced bone pain in tumor studies.</p>Formule :C7H9N3OS2Degré de pureté :99.98%Couleur et forme :SolidMasse moléculaire :215.3γ-DGG acetate(6729-55-1 free base)
CAS :<p>gamma-DGG acetate(6729-55-1 free base) (γ-D-Glutamylglycine) is a competitive blocker of AMPA receptor.</p>Formule :C9H16N2O7Degré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :264.23Basimglurant
CAS :<p>Basimglurant (CTEP Derivative) is a potent, selective and orally available modulator of mGlu5 negative allosteric(Kd of 1.1 nM).</p>Formule :C18H13ClFN3Degré de pureté :98.35%Couleur et forme :SolidMasse moléculaire :325.77(R)-ADX-47273
CAS :<p>(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator(EC50 of 168 nM for potentiation ).</p>Formule :C20H17F2N3O2Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :369.36GYKI-47261 dihydrochloride
CAS :<p>GYKI-47261 dihydrochloride is an AMPA receptor antagonist and CYP2E1 inducer, demonstrating broad-spectrum anticonvulsant and neuroprotective activities.</p>Formule :C18H17Cl3N4Degré de pureté :98.32% - 99.14%Couleur et forme :SolidMasse moléculaire :395.71MMPIP hydrochloride
CAS :<p>MMPIP hydrochloride is a selective antagonist of allosteric mGluR7.</p>Formule :C19H16ClN3O3Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :369.8(S)-3,4-DCPG HCl
<p>(S)-3,4-DCPG HCl is a selective mGluR8a agonist, impacting AV12-664 cells with an EC50 of 31 nM.</p>Formule :C10H10ClNO6Degré de pureté :99.53% - 99.9%Couleur et forme :SoildMasse moléculaire :275.64(S)-3,4-DCPG
CAS :<p>(S)-3,4-DCPG ((S)-3,4-Dicarboxyphenylglycine) is a selective agonist of human metabotropic glutamate receptor 8a (mGluR8a).</p>Formule :C10H9NO6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :239.18STX-107
CAS :<p>STX-107 is a potent and selective mGluR5 agonist for the study of Fragile X Syndrome.</p>Formule :C18H10FN3SDegré de pureté :99.17%Couleur et forme :SolidMasse moléculaire :319.36(S)-AMPA HCl
<p>(S)-AMPA HCl (L-AMPA HCl) is a selective AMPA receptor agonist with potential antidepressant activity. It can be used in research on Parkinson's disease.</p>Formule :C7H11ClN2O4Degré de pureté :99.18%Couleur et forme :SolidMasse moléculaire :222.63MGS0274
CAS :<p>MGS0274, a lipophilic prodrug of mGlu2/3 agonist MGS0008, enhances oral bioavailability, potentially aiding schizophrenia research.</p>Formule :C21H32FNO7Couleur et forme :SolidMasse moléculaire :429.485ML353
<p>ML353 activates TREK-1/2, binds mGlu5 SAM (Ki=18.2 nM), surpasses 5mpep, may address SAM activity/blocking.</p>Formule :C19H15FN2ODegré de pureté :99.98% - 99.98%Couleur et forme :SoildMasse moléculaire :306.331H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-
CAS :<p>1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)- is a low activity isomer of S 18986.</p>Formule :C10H12N2O2SDegré de pureté :99.96%Couleur et forme :SoildMasse moléculaire :224.28VU0483605
CAS :<p>VU0483605 is an effective and selective positive allosteric modulator of mGluR1 with EC50s of 390 and 356 nM for human and rat, respectively.</p>Formule :C20H10Cl3N3O3Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :446.67(S,S)-BMS-984923
CAS :<p>(S,S)-BMS-984923 is a weak mGluR5 modulator with EC50 >1μM; less active than its potent counterpart.</p>Formule :C22H15ClN2O2Couleur et forme :SolidMasse moléculaire :374.82KRP-199 sodium
<p>KRP-199 sodium sodium is highly potent and selective for AMPA-R in vitro and exhibits good neuroprotection in vivo.</p>Formule :C22H12F3N5Na2O7Degré de pureté :97.27%Couleur et forme :SoildMasse moléculaire :561.33(±)-LY367385
CAS :<p>(±)-LY367385 is the racemic form of LY367385, and LY367385 is a highly potent and selective mGluR1a antagonist.</p>Formule :C10H11NO4Couleur et forme :SolidMasse moléculaire :209.201Pomaglumetad methionil anhydrous
CAS :<p>LY2140023, potential schizophrenia treatment, is an oral prodrug of LY404039, a selective mGlu2/3 agonist.</p>Formule :C12H18N2O7S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :366.41LY2812223
CAS :<p>LY2812223: selective mGlu2 agonist; binds mGlu2/mGlu3 (Ki=144/156 nM).</p>Formule :C10H12N4O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :284.29LY3027788 hydrochloride
CAS :<p>LY3027788 HCl, potent oral prodrug of LY3020371, targets mGlu2/3 with antidepressant effects.</p>Formule :C25H32ClF2NO11SCouleur et forme :SolidMasse moléculaire :628.03MGS0028
CAS :<p>MGS0028 is a selective agonist of metabotropic glutamate 2/3 receptor, it could reverse abnormal behaviors in mice induced by isolation rearing.</p>Formule :C8H8FNO5Couleur et forme :SolidMasse moléculaire :217.15LY3020371
CAS :<p>LY3020371: potent, selective mGlu 2/3 receptor antagonist with Ki of 5.26 nM (hmGluR2) and 2.50 nM (hmGluR3); key in depression studies.</p>Formule :C15H15F2NO5SCouleur et forme :SolidMasse moléculaire :359.34L-AP3
CAS :<p>L-AP3 blocks mGluR, inhibits D/L-phosphoserine (IC50: 368/2087 μM).</p>Formule :C3H8NO5PCouleur et forme :White Hygroscopic SolidMasse moléculaire :169.073JF-NP-26
<p>Releases pain-blocking raseglurant under 405 nm light. Inhibits Quisqualate. Analgesic in vivo. Quantum yield: 0.18.</p>Couleur et forme :SolidLY3027788
CAS :<p>LY3027788, potent oral prodrug of LY3020371, is a strong mGlu2/3 antagonist with notable antidepressant effects.</p>Formule :C25H31F2NO11SCouleur et forme :SolidMasse moléculaire :591.58mGluR5 modulator 1
CAS :<p>mGluR5 modulator 1 is a positive modulator for mGluR5, used in schizophrenia and cognitive research.</p>Formule :C18H19ClFN3O2Couleur et forme :SolidMasse moléculaire :363.82MPPG
CAS :<p>MPPG is a selective L-AP4-sensitive receptor antagonist (kD=9.2 μM).</p>Formule :C9H12NO5PCouleur et forme :SolidMasse moléculaire :245.171mGluR3 modulator-1
CAS :<p>1-ethyl-3-morpholin-4-yl tetrahydroisoquinoline: mGluR3 modulator, potential for Parkinson's.</p>Formule :C16H21N3ODegré de pureté :98.99%Couleur et forme :SolidMasse moléculaire :271.36VU0364770 hydrochloride
CAS :<p>VU0364770 hydrochloride: potent, selective mGlu4 PAM; EC50=290 nM (rat), 1.1 μM (human).</p>Formule :C12H10Cl2N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :269.13NS-102
CAS :<p>NS-102 is a glutamate receptor and NMDA receptor antagonist that inhibits erythrocyanine (GluK2) and inhibits specific binding to the glur6 receptor.</p>Formule :C12H11N3O4Degré de pureté :98.48% - 98.95%Couleur et forme :SolidMasse moléculaire :261.23AMN082
CAS :<p>AMN082 is an mGluR7 agonist with antidepressant effects. Neuroprotective effect of AMN082 on neuronal apoptosis in rats with traumatic brain injury.</p>Formule :C28H30Cl2N2Degré de pureté :97.13% - 98.63%Couleur et forme :SolidMasse moléculaire :465.46LY487379
CAS :<p>LY487379: human mGluR2 PAM, boosts glutamate binding, aids cognitive flexibility, may treat schizophrenia. EC50: 1.7 μM (mGlu2), >10 μM (mGlu3).</p>Formule :C21H19F3N2O4SCouleur et forme :SolidMasse moléculaire :452.45VU0422288
CAS :<p>VU0422288 (ML396) is a type III mGlu receptor (mGlus) orthosteric modulator with inhibitory effects on mGluR4.VU0422288 can be used to study Rett syndrome.</p>Formule :C17H11Cl2N3O2Degré de pureté :95.48%Couleur et forme :SolidMasse moléculaire :360.19GYKI 52466 dihydrochloride
CAS :<p>GYKI 52466 dihydrochloride is an AMPA/Kainate receptor antagonist with anticonvulsant activity and can be used to study neurological diseases.</p>Formule :C17H17Cl2N3O2Degré de pureté :99.38%Couleur et forme :SolidMasse moléculaire :366.24GYKI 53655 hydrochloride
CAS :<p>GYKI 53655 hydrochloride (LY300168 hydrochloride) is an antagonist of AMPA and is used in the study of neurological disorders.</p>Formule :C19H21ClN4O3Degré de pureté :98.02%Couleur et forme :SolidMasse moléculaire :388.85JNJ-46778212
CAS :<p>JNJ-46778212 (VU 0409551) is a selective and potent mGlu5 allosteric modulator (EC50: 260 nM) for the study of neurodissection.</p>Formule :C20H17FN2O3Degré de pureté :99.24%Couleur et forme :SolidMasse moléculaire :352.36Ro 01-6128
CAS :<p>Positive allosteric modulator of mGlu1 receptors</p>Formule :C17H17NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :283.32EGLU
CAS :<p>EGLU, an antidepressant and potent mGluR-2 antagonist, binds with a 66 μM Kd to (lS,3S)-ACPD sites.</p>Formule :C7H13NO4Degré de pureté :99.98%Couleur et forme :SolidMasse moléculaire :175.18LY341495
CAS :<p>LY341495 is a potent metabotropic glutamate receptor antagonist and can be used to study neurological disorders.</p>Formule :C20H19NO5Degré de pureté :98.53% - 99.37%Couleur et forme :SolidMasse moléculaire :353.37γ-DGG
CAS :<p>gamma-DGG is a competitive blocker of AMPA receptor.</p>Formule :C7H12N2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :204.18CFMTI
CAS :<p>CFMTI: potent mGluR1 allosteric antagonist, 2000x selectivity over mGluR5, IC50: 2.6 nM.</p>Formule :C19H16FN5ODegré de pureté :97.23%Couleur et forme :SolidMasse moléculaire :349.36Chelidamic acid
CAS :<p>Chelidamic acid is a heterocyclic organic acid with a pyran skeleton. Chelidamic acid is inhibitors of glutamate decarboxylase, with a Ki of 33 μM.</p>Formule :C7H5NO5Degré de pureté :98.11%Couleur et forme :Pale Yellow PowderMasse moléculaire :183.12VU-1545
CAS :<p>VU-1545 is mGlu5 positive allosteric modulator.</p>Formule :C22H15FN4O3Degré de pureté :98.8%Couleur et forme :SolidMasse moléculaire :402.38(RS)-3-Hydroxyphenylglycine
CAS :<p>(RS)-3-Hydroxyphenylglycine is a PI-linked metabotropic glutamate receptors agonist.</p>Formule :C8H9NO3Degré de pureté :99.29%Couleur et forme :SolidMasse moléculaire :167.16FTIDC
CAS :<p>FTIDC: potent, selective mGluR1 allosteric antagonist, weak on mGluR5. IC50: human 5.8 nM, mouse 3.1 nM. Noncompetitive.</p>Formule :C18H23FN6ODegré de pureté :94.58%Couleur et forme :SolidMasse moléculaire :358.41E4CPG
CAS :<p>E4CPG is a novel group I/II metabotropic glutamate receptor antagonist, more potent than (RS)-MCPG.</p>Formule :C11H13NO4Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :223.23DNQX
CAS :<p>DNQX (FG 9041) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively)</p>Formule :C8H4N4O6Degré de pureté :97.27% - 99.1%Couleur et forme :Off-White Powder With A Yellow TingeMasse moléculaire :252.14VU-29
CAS :<p>VU-29 is a positive allosteric mGlu5 receptor modulator with EC50=9 nM and Ki=244 nM for rmGluR5. It is selective for mGluR5 relative to other mGluR subtypes.</p>Formule :C22H16N4O3Degré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :384.39VU0361737
CAS :VU0361737 (ML-128) is a mGlu4 PAM; EC50 is 240 nM (human) and 110 nM (rat), weak at mGlu5/8, inactive at mGlu1/2/3/6/7, CNS-penetrant.Formule :C13H11ClN2O2Degré de pureté :99.60% - 99.85%Couleur et forme :SolidMasse moléculaire :262.69(S)-ATPO
CAS :<p>(S)-ATPO is Competitive antagonist at GluR1-4 (AMPA-preferring) receptors.</p>Formule :C11H19N2O7PDegré de pureté :98.37% - 99.41%Couleur et forme :SolidMasse moléculaire :322.25CX614
CAS :<p>CX614 is a positive allosteric modulator of the AMPA receptor concerning AMPA.</p>Formule :C13H13NO4Degré de pureté :97.37%Couleur et forme :SolidMasse moléculaire :247.25ADX-47273
CAS :<p>ADX-47273 (BA 94673139) is a positive and selective allosteric modulator for the metabotropic glutamate receptor subtype mGluR5(EC50=170 nM).</p>Formule :C20H17F2N3O2Degré de pureté :97% - 99.18%Couleur et forme :SolidMasse moléculaire :369.36Farampator
CAS :<p>Farampator (CX-691) (CX-691;Org24448) is a positive modulator of AMPA receptor.</p>Formule :C12H13N3O2Degré de pureté :99.84% - >99.99%Couleur et forme :SolidMasse moléculaire :231.25AZD-8529
CAS :<p>AZD-8529: selective, oral mGluR2 modulator, EC50 285 nM; inactive on mGluR1,3-8 at 20-25 M.</p>Formule :C24H24F3N5O3Couleur et forme :SolidMasse moléculaire :487.47NBQX
CAS :<p>NBQX (FG9202) is a potent, selective and competitive AMPA receptor antagonist. Neuroprotective and anticonvulsant; active in vivo.</p>Formule :C12H8N4O6SDegré de pureté :97.66% - 99.42%Couleur et forme :SolidMasse moléculaire :336.28XAP044
CAS :<p>XAP044 blocks mGlu7, inhibiting long-term potentiation in mouse brain with a half-maximal effect at 88nm.</p>Formule :C15H9IO4Degré de pureté :97.41%Couleur et forme :SolidMasse moléculaire :380.13ADX88178
CAS :<p>ADX88178 is a potent positive allosteric modulator for metabotropic glutamate receptor 4 (mGluR4) with EC50 of 4 nM for human mGluR4.</p>Formule :C12H12N6SDegré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :272.33SIB-1757
CAS :<p>SIB-1757 (6-methyl-2-[(E)-phenyldiazenyl]pyridin-3) is a selective antagonist of mGlu5 metabotropic glutamate receptor subtype (hmGlu5, IC50 : 0.4 μM)</p>Formule :C12H11N3ODegré de pureté :97.37%Couleur et forme :SolidMasse moléculaire :213.24MPEP
CAS :<p>MPEP is a selective mGlu5 receptor antagonist with IC50 of 36 nM, exhibits no appreciable activity at mGlu1b/2/3/4a/7b/8a/6 receptors.</p>Formule :C14H11NDegré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :193.24(RS)-MCPG
CAS :<p>(RS)-MCPG ((±)-MCPG) is a non-selective group I/II metabotropic glutamate receptor antagonist.</p>Formule :C10H11NO4Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :209.2TCN238
CAS :<p>TCN238 is an orally bioavailable positive allosteric modulator of the metabotropic glutamate receptor 4 (mGluR4with an EC50 of 1 μM).</p>Formule :C12H11N3Degré de pureté :99.9% - 99.92%Couleur et forme :SolidMasse moléculaire :197.24VU0364770
CAS :<p>VU0364770 (VU 0364770)(EC50=1.1 μM), a positive allosteric modulator(PAM) of mGlu4, shows insignificant activity at 68 other receptors, including other mGlu</p>Formule :C12H9ClN2ODegré de pureté :99.65% - >99.99%Couleur et forme :SolidMasse moléculaire :232.67CNQX
CAS :<p>CNQX (FG9065) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors, respectively)</p>Formule :C9H4N4O4Degré de pureté :99.70%Couleur et forme :Pale Yellow SolidMasse moléculaire :232.15PHCCC
CAS :<p>PHCCC is a Group I mGluR antagonist and enhances mGluR4 function; also blocks mGluR2/8.</p>Formule :C17H14N2O3Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :294.31-BCP
CAS :<p>1-BCP (Piperonylic acid piperidide) is a centrally active drug that modulates AMPA receptor gated currents.</p>Formule :C13H15NO3Degré de pureté :99.60%Couleur et forme :SolidMasse moléculaire :233.26(S)-3-Hydroxyphenylglycine
CAS :<p>(S)-3-Hydroxyphenylglycine is an agonist of group I metabotropic glutamate receptors (mGluRs).</p>Formule :C8H9NO3Degré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :167.16JNJ16259685
CAS :<p>JNJ16259685 (TN.T 16259685) is a selective mGluR1 antagonist, and inhibits the synaptic activation of mGluR1 in a concentration-dependent manner with IC50 of 19</p>Formule :C20H23NO3Degré de pureté :98.31%Couleur et forme :SolidMasse moléculaire :325.4Lu AF21934
CAS :<p>Lu AF21934 is a brain-penetrant and selective mGlu4 receptor positive allosteric modulator (IC50: 500 nM, human).</p>Formule :C14H16Cl2N2O2Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :315.2LY-404187
CAS :<p>LY404187 is a positive allosteric modulator of AMPA receptors</p>Formule :C19H22N2O2SDegré de pureté :99.34%Couleur et forme :SolidMasse moléculaire :342.46IDRA-21
CAS :IDRA-21 is a positive AMPA receptor modulator.Formule :C8H9ClN2O2SDegré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :232.69trans-ACPD
CAS :<p>trans-ACPD ((±)-trans-ACPD) is an equimolecular mixture of (1S, 3R)- and (1R, 3S)-ACPD.</p>Formule :C7H11NO4Degré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :173.17Ro0711401
CAS :<p>Ro0711401 is an agonist of mGlu1 receptor.</p>Formule :C18H11F3N2O3Degré de pureté :97.57%Couleur et forme :SolidMasse moléculaire :360.29YM90K
CAS :<p>YM90K (6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)-) hydrochloride is an antagonist of AMPA receptor.</p>Formule :C11H8ClN5O4Degré de pureté :98.23%Couleur et forme :SolidMasse moléculaire :309.66HBT1
CAS :<p>HBT1 is an AMPA receptor potentiator that induces production of brain-derived neurotrophic factor (BDNF) and exhibits little agonistic effect in primary neurons</p>Formule :C16H17F3N4O2SDegré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :386.393-MATIDA
CAS :<p>3-MATIDA is an effective mGluR-1 antagonist (IC50: 6.3 μM, rat mGluR-1a).</p>Formule :C8H9NO4SDegré de pureté :99.75% - 99.96%Couleur et forme :SolidMasse moléculaire :215.23VU 0357121
CAS :<p>VU0357121, a positive allosteric modulator of mGlu5 (EC50: 33 nM), is inactive or very weakly antagonizing at other mGlu receptor subtypes.</p>Formule :C17H17F2NO2Degré de pureté :99% - >99.99%Couleur et forme :SolidMasse moléculaire :305.32MTEP hydrochloride
CAS :<p>MTEP hydrochloride (MTEP) is non-competitive mGlu5 antagonist (IC50 and Ki of 5 nM and 16 nM, respectively)</p>Formule :C11H9ClN2SDegré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :236.72FITM
CAS :<p>FITM is a potent negative allosteric modulator of mGlu1 receptor(Ki : 2.5 nM).</p>Formule :C18H18FN5OSDegré de pureté :97.25%Couleur et forme :SolidMasse moléculaire :371.43ML 254
CAS :<p>是一种化学合成中的砌块</p>Formule :C18H15FN2O2Degré de pureté :98.09%Couleur et forme :SolidMasse moléculaire :310.32AMN082 free base
CAS :<p>AMN082 free base is a metabotropic glutamate receptor 7 allosteric agonist.</p>Formule :C28H28N2Degré de pureté :97.75% - 97.79%Couleur et forme :SolidMasse moléculaire :392.54MPEP hydrochloride
CAS :<p>MPEP hydrochloride is an effective and highly specific non-competitive antagonist at the mGlu5 receptor subtype (IC50: 36 nM).</p>Formule :C14H12ClNDegré de pureté :99.87% - >99.99%Couleur et forme :SolidMasse moléculaire :229.7CX516
CAS :<p>CX516 (Ampalex), an ampakine and nootropic, acts as an AMPA receptor positive allosteric modulator as a therapy for Alzheimer's disease, schizophrenia and MCI.</p>Formule :C14H15N3ODegré de pureté :99.04% - ≥95%Couleur et forme :Tan SolidMasse moléculaire :241.29MTEP
CAS :<p>MTEP: potent, selective mGluR5 antagonist; IC50=5 nM, Ki=16 nM; may have antidepressant/anxiolytic effects; useful in Parkinson's research.</p>Formule :C11H8N2SCouleur et forme :SolidMasse moléculaire :200.26Ro 67-7476
CAS :<p>Ro 67-7476 is a positive allosteric modulator of mGlu1 receptors.</p>Formule :C17H18FNO2SDegré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :319.39CTEP
CAS :<p>CTEP (RO 4956371) (RO4956371) is a novel, long-acting, orally bioavailable allosteric antagonist of mGlu5 receptor with IC50 of 2.2 nM, shows >1000-fold</p>Formule :C19H13ClF3N3ODegré de pureté :99.17%Couleur et forme :SolidMasse moléculaire :391.77VU0155094
CAS :<p>VU0155094 (ML 397) is a positive allosteric modulator with differential activity at the various group III mGluRs.</p>Formule :C24H24N2O4SDegré de pureté :97.21%Couleur et forme :SolidMasse moléculaire :436.52Caroverine hydrochloride
CAS :Caroverine HCL: Blocks NMDA/AMPA receptors, antioxidant, calcium-blocker, and vasorelaxant, used for tinnitus research.Formule :C22H28ClN3O2Degré de pureté :98.37% - 98.75%Couleur et forme :SolidMasse moléculaire :401.9VU 0364439
CAS :<p>VU 0364439 is a mGlu4 positive allosteric modulator (C50: 19.8 nM).</p>Formule :C18H13Cl2N3O3SDegré de pureté :97.9%Couleur et forme :SolidMasse moléculaire :422.29JNJ-42153605
CAS :<p>JNJ-42153605 is a mGlu2 receptor positive allosteric modulator (EC50: 17 nM).</p>Formule :C22H23F3N4Degré de pureté :97.25% - 98.57%Couleur et forme :SolidMasse moléculaire :400.44VU0155041
CAS :<p>VU0155041 is an effective and positive allosteric modulator/allosteric agonist at mGlu4 receptors (EC50: 798/693 nM, at human/rat).</p>Formule :C14H15Cl2NO3Degré de pureté :99.52% - 99.56%Couleur et forme :SolidMasse moléculaire :316.18JNJ-40411813
CAS :<p>JNJ-40411813 (ADX-71149) (ADX-71149) is a new positive allosteric modulator of the metabotropic glutamate 2 receptor (mGlu2R, EC50: 147 nM).</p>Formule :C20H25ClN2ODegré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :344.88
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