AChR
Les inhibiteurs des récepteurs de l'acétylcholine (AChR) sont des composés qui bloquent l'activité des récepteurs de l'acétylcholine, essentiels pour la neurotransmission dans les systèmes nerveux central et périphérique. Les AChR jouent un rôle crucial dans la contraction musculaire, la mémoire et les fonctions cognitives. Les inhibiteurs des AChR sont utilisés pour étudier des conditions telles que la myasthénie grave, la maladie d'Alzheimer et d'autres troubles neurologiques. En modulant l'activité des AChR, ces inhibiteurs peuvent aider à démêler les complexités de la signalisation cholinergique dans le cerveau. Chez CymitQuimica, nous fournissons une gamme d'inhibiteurs des AChR pour soutenir vos recherches en neurosciences, pharmacologie et maladies neurodégénératives.
575 produits trouvés pour "AChR"
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A-85380 HCl
CAS :<p>A-85380 is an agonist of nicotinic acetylcholine receptor.</p>Formule :C9H14Cl2N2OCouleur et forme :SolidMasse moléculaire :237.13Phenglutarimid
CAS :<p>Phenglutarimid is an anticholinergic. It is used as an antiparkinsonian agent.</p>Formule :C17H24N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :288.38Pirenzepine
CAS :<p>Pirenzepine targets M1 mAChR, curbs acid secretion, eases spasms, and has anti-cancer properties.</p>Formule :C19H21N5O2Couleur et forme :SolidMasse moléculaire :351.4ENS-163 phosphate
CAS :<p>Ens-163 phosphate is a muscarinic M1 receptor agonist. It is selective.</p>Formule :C11H19N2O5PSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :322.32TMPH hydrochloride
CAS :<p>neuronal nicotinic ACh receptors (nAChRs) antagonist</p>Formule :C16H32ClNO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :305.889-CP-Ade Mesylate
CAS :<p>9-CP-Ade Mesylate (9 CP Ade Mesylate) is a cell-permeable, stable and non-competitive inhibitor of adenylate cyclase.</p>Formule :C11H17N5O3SDegré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :299.35Arecaidine but-2-ynyl ester tosylate
CAS :mAChR M2 agonistFormule :C18H23NO5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :365.44GSK575594A
CAS :<p>GSK575594A is a selective agonist of GPR55.</p>Formule :C24H23F2N3O3SCouleur et forme :SolidMasse moléculaire :471.52(R)-Oxybutynin
CAS :<p>(R)-Oxybutynin: oral muscarinic blocker with antispasmodic effects, used in neurogenic bladder research.</p>Formule :C22H31NO3Couleur et forme :SolidMasse moléculaire :357.49AC-42
CAS :<p>AC-42 is an allosteric agonist of M1 muscarinic receptor.</p>Formule :C20H31NOCouleur et forme :SolidMasse moléculaire :301.47α7 nAchR-JAK2-STAT3 agonist 1
CAS :<p>α7 nAchR-JAK2-STAT3 agonist 1 is a potent inhibitor of the α7 nAchR-JAK2-STAT3 pathway that acts on nitric oxide (NO) (IC50: 0.32 μM).</p>Formule :C25H30O6Couleur et forme :SolidMasse moléculaire :426.5Ethybenztropine
CAS :<p>Ethybenztropine is an anticholinergic used as an antiparkinsonian agent and may also act as a dopamine reuptake inhibitor.</p>Formule :C22H27NODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :321.46Anabasine hydrochloride
CAS :<p>neuronal nicotinic ACh receptor partial agonist</p>Formule :C10H15ClN2Degré de pureté :98%Couleur et forme :White To Off-White SolidMasse moléculaire :198.693Flupyrimin
CAS :<p>Flupyrimin is the insect nicotinic acetylcholine receptor (nAChR) antagonist [1].</p>Formule :C13H9ClF3N3OCouleur et forme :SolidMasse moléculaire :315.68Adenylyl cyclase type 2 agonist-1
CAS :<p>Potent AC2 agonist with an EC50 of 90 nM, potential for respiratory disease treatment.</p>Formule :C27H17BrClNO5Couleur et forme :SolidMasse moléculaire :550.78RJR-2403 oxalate
CAS :<p>RJR-2403 oxalate is a highly selective agonist of α4β2 subtype nicotinic receptor.</p>Formule :C14H18N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :278.308Bibn 140
CAS :<p>Bibn 140 is a highly selective M2 antagonist, it is used to treat Alzheimer's disease and other cognitive disorders.</p>Formule :C32H44N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :532.72AZD 0328
CAS :<p>AZD 0328 is a nicotinic receptor agonist for α7 neurons.</p>Formule :C13H16N2OCouleur et forme :SolidMasse moléculaire :216.28Nelonicline citrate
CAS :<p>Nelonicline citrate (ABT-126) is a selective α7 nAChR agonist with a Ki of 12.3 nM, studied for schizophrenia and Alzheimer's.</p>Formule :C23H27N3O8SCouleur et forme :SolidMasse moléculaire :505.54S16961
CAS :<p>S16961 (S169611) is an agonist of nicotinic receptor.</p>Formule :C41H71NO6Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :674.01N-0861 racemate
CAS :<p>N-0861 racemate is the racemate of N-0861.</p>Formule :C13H17N5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :243.31Bradanicline
CAS :<p>Bradanicline: potent α7 nAChR agonist, EC50=17 nM, Ki=1.4 nM, used in cognitive disorder research.</p>Formule :C22H23N3O2Couleur et forme :SolidMasse moléculaire :361.44Afacifenacin
CAS :<p>Afacifenacin (SMP-986) fumarate is an M3-selective antagonist for ischemic heart disease and urinary disorders.</p>Formule :C27H26F3N3O2Degré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :481.51mAChr-in-1
CAS :<p>mAChR-IN-1 is muscarinic cholinergic receptor(mAChR) antagonist (IC50=17 nM).</p>Formule :C23H25IN2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :488.364-DAMP
CAS :<p>4-DAMP (4-DAMP methiodide) is a selective muscarinic M1 and M3 subtype receptor antagonist used in the study of allergic rhinitis and cardiovascular disease.</p>Formule :C21H26INO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :451.34Asoxime dichloride
CAS :<p>Asoxime dichloride (HI-6) blocks AChRs, including α7 nAChR, and boosts vaccination in the nervous system.</p>Formule :C14H16Cl2N4O3Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :359.21Tarafenacin D-tartrate
CAS :Tarafenacin D-tartrate is a highly selective M3 muscarinic receptor antagonist (Ki= 0.19 nM), ~200 fold selectivity over the M2 receptor.Formule :C25H26F4N2O8Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :558.48Camylofine
CAS :<p>Camylofine (Avacan) is an antimuscarinic, used for relaxing smooth muscle.</p>Formule :C19H32N2O2·2HClDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :393.4(Rac)-VU 6008667
CAS :<p>(Rac)-VU 6008667 is a selective M5 NAM with IC50 of 1.8 μM, high CNS penetration.</p>Formule :C24H17ClF2N2O2Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :438.85Pentolinium Tartrate
CAS :<p>Pentolinium Tartrate (Pendine) is a nicotinic antagonist that has been used as a ganglionic blocking agent in hypertension.</p>Formule :C15H32N2·2C4H5O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :538.6AF-DX 384 free base
CAS :<p>AF-DX 384 free base is an M2 mAChR and M4 mAChR antagonist, useful in research on neurodivisions and diseases such as Parkinson's.</p>Formule :C27H38N6O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :478.63Pozanicline
CAS :<p>Pozanicline, a selective α4β2 nAChR partial agonist (Ki=16 nM), may treat nicotine addiction by reversing cognitive deficits.</p>Formule :C11H16N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :192.26CB-6673567
CAS :<p>CB-6673567 is a selective inhibitor of adenylyl cyclase.</p>Formule :C19H14N4O3Couleur et forme :SolidMasse moléculaire :346.34NGX-267
CAS :<p>NGX-267, a muscarinic M1 agonist, is used potentially for the treatment of Xerostomia, Alzheimer's disease and cognitive.</p>Formule :C10H18N2OSCouleur et forme :SolidMasse moléculaire :214.33Dac 5945
CAS :<p>DAC 5945 is a more effective muscarinic antagonist in the airways than in the heart.</p>Formule :C19H30ClN3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :351.91Hexocyclium metilsulfate
CAS :<p>Hexocyclium metilsulfate has anti-gastric secretory effects in humans.</p>Formule :C21H36N2O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :428.59GS 283
CAS :<p>GS 283 is a Ca(2+) antagonist. GS 283 is also a weak histamine and muscarinic receptor blocker in rat and guinea pig tracheal smooth muscles.</p>Formule :C17H17NO3Couleur et forme :SolidMasse moléculaire :283.32(R)-VU 6008667
CAS :(R)-VU 6008667 is devoid of M5 NAM activity (IC50>10 μM).Formule :C24H17ClF2N2O2Couleur et forme :SolidMasse moléculaire :438.85Anisodine hydrobromide
CAS :<p>Anisodine hydrobromide is an inhibitor of adenosine kinase.</p>Formule :C17H22BrNO5Couleur et forme :White Crystals Or Crystalline PowderMasse moléculaire :400.27Btm 1042
CAS :<p>Btm 1042 is an antispasmodic drug. It has been found to depress twitch responses in the ileum of guinea pigs.</p>Formule :C21H26ClN3OSCouleur et forme :SolidMasse moléculaire :403.97Hyoscyamine hydrobromide
CAS :<p>Hyoscyamine hydrobromide is an agent of anticholinergic.</p>Formule :C17H24BrNO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :370.28Sazetidine A dihydrochloride
CAS :<p>α4β2 nicotinic acetylcholine receptor ligand</p>Formule :C15H21ClN2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :296.79FR 121196
CAS :<p>FR 121196, a potential antidementia drug, ameliorates the impaired memory of rat in the Morris water maze.</p>Formule :C12H16FN3O3SCouleur et forme :SolidMasse moléculaire :301.34Prifuroline
CAS :<p>Prifuroline is an agent of antiarrhythmic.</p>Formule :C14H16N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :228.29Epibatidine 2HCl
CAS :<p>Epibatidine 2HCl is a potent nicotinic agonist.</p>Formule :C11H15Cl3N2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :281.61Flutropium Bromide
CAS :<p>Flutropium Bromide is a competitive antagonist of acetylcholine. It is used to treat asthma and chronic obstructive pulmonary.</p>Formule :C24H29BrFNO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :478.39Vesamicol
CAS :Vesamicol is an experimental drug. It acting presynaptically by inhibiting acetylcholine uptake into synaptic vesicles and reducing its release.Formule :C17H25NODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :259.39Siltenzepine
CAS :<p>Siltenzepine is an agent of anti-acid agent,and used in the treatment of peptic ulcers.</p>Formule :C19H20ClN3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :389.83L 858051
CAS :<p>L 858051 activates adenylate cyclase. It also inhibits glucose transport in rat adipocytes.</p>Formule :C29H48N2O7Couleur et forme :SolidMasse moléculaire :536.7DBO-83
CAS :<p>DBO-83, an agonist of nicotinic acetylcholine receptors (nAChRs), has anti-amnesic and antinociceptive activities.</p>Formule :C10H15Cl3N4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :297.61ADX-10061
CAS :<p>ADX-10061 is a dopamine D1 receptor antagonist.</p>Formule :C19H20N2O4Couleur et forme :SolidMasse moléculaire :340.37UP202-56
CAS :<p>UP202-56 is an adenosinergic agonist and is an adenosine analog.</p>Formule :C33H37N7O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :595.69JN403
CAS :<p>JN403 is a selective agonist of nicotinic acetylcholine receptor alpha7.</p>Formule :C16H21FN2O2Couleur et forme :SolidMasse moléculaire :292.35CB-7921220
CAS :<p>CB-7921220 (6-[2-(4-Aminophenyl)vinyl]-2-pyridinecarboxylic acid) is an inhibitor of adenylate cyclase.</p>Formule :C14H12N2O2Degré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :240.26Tebanicline tosylate
CAS :<p>Tebanicline: synthetic, potent, non-opioid analgesic, less toxic than epibatidine; relieves neuropathic pain, acts on α3β4 and α4β2 nicotinic receptors.</p>Formule :C16H19ClN2O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :370.85Cimetropium Bromide
CAS :<p>Cimetropium Bromide is a mAChR antagonist used for long-term treatment of irritable bowel syndrome.</p>Formule :C21H28BrNO4Couleur et forme :SolidMasse moléculaire :438.36GP531
CAS :<p>GP531, a second-gen adenosine regulator, is inactive at rest but boosts adenosine in ischemia.</p>Formule :C16H21N5O4Couleur et forme :SolidMasse moléculaire :347.37Terodiline hydrochloride
CAS :<p>Terodiline hydrochloride is an antagonist of M1-selective muscarinic receptor (mAChR)(Kbs of 15, 160, 280, and 198 nM in rabbit vas deferens (M1), atria (M2),</p>Formule :C20H28ClNDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :317.9YM-46303
CAS :<p>YM-46303 is a selective and potent muscarinic receptor antagonist that exhibits high affinity for the M3 receptor.YM-46303 can be used to study bradycardia in</p>Formule :C20H23ClN2O2Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :358.86CHF5407
CAS :<p>CHF5407（SVT-47060） is a potent and selective muscarinic M3 receptor antagonist with prolonged action at muscarinic receptors.CHF5407 has an effect on</p>Formule :C27H25BrF4N2O3SDegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :613.46Meseclazone
CAS :<p>Meseclazone has anti-inflammatory, analgesic, and antipyretic activity. Meseclazone shows inhibitory potency of secondary phase ADP aggregation.</p>Formule :C11H10ClNO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :239.65YM-58790
CAS :<p>YM-58790 is a potent mAChR blocker with Ki values of 28 nM (M1), 260 nM (M2), 15 nM (M3), and reduces bladder contractions in rats.</p>Formule :C27H31N3O2Degré de pureté :98.59%Couleur et forme :SoildMasse moléculaire :429.55Metixene hydrochloride
CAS :<p>Metixene hydrochloride is an anticholinergic antiparkinsonian agent.</p>Formule :C20H24ClNSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :345.93UB 165 fumarate
CAS :<p>UB 165 fumarate is a nAChR agonist, α4β2 partial, α3β2 full, with a 0.27 nM Ki for [3H]-nicotine in rat brain.</p>Formule :C17H19ClN2O4Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :350.8CDD0102
CAS :<p>CDD0102 is a potent agonist of M1 Muscarinic receptor.</p>Formule :C8H12N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :180.21PQCA
CAS :<p>PQCA is a selective M1 receptor modulator with EC50s of 49 nM (monkey) and 135 nM (human), potential for Alzheimer's treatment.</p>Formule :C22H20N4O3Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :388.425-Iodo-A-85380 dihydrochloride
CAS :α4β2 and α6β2 nicotinic acetylcholine receptors agonistFormule :C9H13Cl2IN2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :363.02Dimethyl-W84 (dibromide)
CAS :<p>Dimethyl-W84, selective M2 muscarinic receptor modulator; slows N-methylscopolamine release, EC50=3 nM.</p>Formule :C34H48Br2N4O4Couleur et forme :SolidMasse moléculaire :736.59LY 2087101
CAS :<p>Allosteric potentiator of α7, α4β2 and α4β4 nAChRs</p>Formule :C15H11FN2OS2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :318.39Penehyclidine hydrochloride
CAS :<p>Penehyclidine hydrochloride: M1/M3 antagonist, activates NF-κB, anti-inflammatory, anticholinergic.</p>Formule :C20H30ClNO2Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :351.91AR-R 17779 hydrochloride
CAS :<p>AR-R17779 hydrochloride: potent α7 nAChR agonist; K i : 92 nM (α7), 16,000 nM (α4β2); enhances rat cognition; anxiolytic; anti-inflammatory.</p>Formule :C9H15ClN2O2Couleur et forme :SolidMasse moléculaire :218.68Elucaine
CAS :Elucaine is an antagonist of the muscarinic acetylcholine receptor. It has anti-ulcerative activity.Formule :C19H23NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :297.39(R,R)-Glycopyrrolate
CAS :<p>(R,R)-Glycopyrrolate is an agent of anticholinergic, has the ability to reduce the frequency of drooling in vivo with developmental disabilities.</p>Formule :C19H28BrNO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :398.34SIB 1508Y maleate
CAS :<p>neuronal nicotinic ACh receptor agonist</p>Formule :C16H18N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :302.33LRE1
CAS :<p>LRE1 is a specific and allosteric soluble adenylyl cyclase inhibitor.</p>Formule :C12H13ClN4SDegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :280.78Sulfoxaflor
CAS :<p>Sulfoxaflor (GF 2032) is an agonist of nAChR1 and nAChR2 subtypes and a systemic insecticide. Cost-effective and quality-assured.</p>Formule :C10H10F3N3OSDegré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :277.27Darenzepine
CAS :<p>Darenzepine is a muscarinic receptor inhibitor.</p>Formule :C21H21N3O2Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :347.41Terodiline
CAS :<p>Terodiline is an orally available selective muscarinic M1 receptor and calcium channel antagonist for the study of diseases caused by abnormal bladder function.</p>Formule :C20H27NDegré de pureté :98.20% - 99.59%Couleur et forme :SolidMasse moléculaire :281.44Methacholine bromide
CAS :<p>Methacholine bromide is a potent M3 agonist for diagnosing asthma by identifying bronchial hyperresponsiveness.</p>Formule :C8H18BrNO2Couleur et forme :SolidMasse moléculaire :240.141Nuvenzepine
CAS :Nuvenzepine is an antagonist of mAChR. It has the potential for gastrospasm treatment.Formule :C19H20N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :336.39DA 4626
CAS :<p>DA 4626 is an H2-receptor antagonist with KB values akin to those in standard assays.</p>Formule :C14H18N4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :242.32SIB-1553A hydrochloride
CAS :<p>SIB-1553A hydrochloride is a nicotinic acetylcholine receptor agonist and a selective neuronal nAChR ligand</p>Formule :C13H20ClNOSDegré de pureté :99.56% - 99.73%Couleur et forme :SolidMasse moléculaire :273.82Telenzepine
CAS :<p>Telenzepine is a potent and selective M1 antimuscarinic.</p>Formule :C19H22N4O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :370.47AC260584
CAS :AC260584 is an M1 muscarinic receptor allosteric agonist (pEC50: 7.6).Formule :C20H29FN2O2Couleur et forme :SolidMasse moléculaire :348.45Neramexane Mesylate
CAS :<p>Neramexane: NMDA & nicotinic receptor blocker with neuroprotective, antidepressant, and cognitive-enhancing effects.</p>Formule :C12H27NO3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :265.41ML381
CAS :<p>ML381 is a M5-orthosteric antagonist with a high selectivity of muscarinic subtype.</p>Formule :C21H21N3O4Couleur et forme :SolidMasse moléculaire :379.41ML169
CAS :<p>ML169 is a selective and brain penetrant M1 positive allosteric modulator (PAM).</p>Formule :C21H17BrFN3O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :506.34Zamifenacin
CAS :Zamifenacin obviously decreases colonic motility in irritable bowel syndrome. Zamifenacin is an effective gut-selective muscarinic M3 receptor antagonist.Formule :C27H29NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :415.52BNC375
CAS :BNC375 is a α7 nAChRs type I positive allosteric modulator (EC50: 1.9 μM).Formule :C19H23ClN2O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :394.92(R,R)-Reboxetine mesylate
CAS :<p>(R,R)-Reboxetine mesylate: Antidepressant, high bioavailability, (R,R) enantiomer, selective for noradrenaline, low toxicity.</p>Formule :C20H27NO6SCouleur et forme :SolidMasse moléculaire :409.5GAT107
CAS :<p>GAT107, a strong α7 nicotinic receptor modulator, aids inflammation and neuropathic pain in mice.</p>Formule :C18H17BrN2O2SDegré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :405.31M1 ligand 1
CAS :<p>Compound 3b-b: N-desmethyl arecoline derivative, muscarinic M1 ligand, potential PET radiotracer.</p>Formule :C20H21NO2Couleur et forme :SolidMasse moléculaire :307.39Benzatropine
CAS :Benzatropine: Central muscarinic blocker, inhibits dopamine uptake, treats Parkinson's symptoms.Formule :C21H25NODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :307.43Muscarine iodide
CAS :<p>Muscarinic acetylcholine receptor agonist</p>Formule :C9H20INO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :301.17Tridihexethyl chloride
CAS :<p>Tridihexethyl is an anticholinergic, antimuscarinic, and antispasmolytic drug, which can be used to treat acquired nystagmus or peptic ulcer disease.</p>Formule :C21H36ClNOCouleur et forme :SolidMasse moléculaire :353.97TC 2559 difumarate
CAS :partial agonist of α4β2 nicotinic acetylcholine receptorFormule :C12H18N2OC4H404Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :380.39TC299423
CAS :<p>TC299423 is a novel agonist for nicotinic acetylcholine receptors (nAChRs). TC299423 modestly selectively targets α6β2 subtype.</p>Formule :C11H15N3Couleur et forme :SolidMasse moléculaire :189.26SM-21 maleate
CAS :<p>Increases release of acetylcholine,σ2 antagonist</p>Formule :C22H28ClNO7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :453.91TC 1698 dihydrochloride
CAS :<p>nicotinic α7 receptor agonist</p>Formule :C13H18N2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :202.3Beperidium iodide
CAS :<p>Beperidium iodide is a competitive antagonist of the acetylcholine receptor (pA2: 7.93).</p>Formule :C23H34IN3O3Couleur et forme :SolidMasse moléculaire :527.44WIN 62,577
CAS :<p>WIN 62,577 is a allosteric antagonist of mAChR.</p>Formule :C29H31N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :437.58Benzamide Derivative 1
CAS :Benzamide Derivative 1 Benzamide derivative with gastrokinetic activity.Benzamide Derivative 1 can be used in the study of gastrointestinal diseases.Formule :C22H34ClN3O3Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :423.98Muscarine chloride
CAS :<p>Muscarine chloride is a toxic alkaloid found in Amanita muscaria and other fungi of the Inocybe species.</p>Formule :C9H20ClNO2Couleur et forme :SolidMasse moléculaire :209.71PHA 543613
CAS :<p>PHA 543613 is a specific agonist of α7 nAChR (Ki = 8.8 nM) and can be used in studies about the cognitive deficits of Alzheimer's disease and schizophrenia.</p>Formule :C15H17N3O2Degré de pureté :99.43% - 99.96%Couleur et forme :SolidMasse moléculaire :271.31rel-(1R,2R)-Vesamicol Hydrochloride
CAS :<p>Vesamicol hydrochloride ((±)-AH5183 hydrochloride) is a acetylcholine transport inhibitor.</p>Formule :C17H26ClNODegré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :295.85Temiverine hydrochloride
CAS :Temiverine hydrochloride is a potential calcium channel antagonist with anticholinergic effects that inhibits some of the functions of atropine.Formule :C24H36ClNO3Degré de pureté :99.26% - 99.43%Couleur et forme :SolidMasse moléculaire :422NB001
CAS :<p>NB001 (HTS 09836) is an inhibitor of adenyl cyclase 1 exhibiting effects on neural and non-neural pain.</p>Formule :C12H20N6ODegré de pureté :99.69%Couleur et forme :Off-White To Pale Pink SolidMasse moléculaire :264.33JNJ-39393406
CAS :<p>JNJ-39393406 is an α7 nicotinic acetylcholine receptor positive allosteric modulator for the study of tobacco dependence and Alzheimer's disease.</p>Formule :C19H18F2N6O3Degré de pureté :98.5%Couleur et forme :SolidMasse moléculaire :416.38Desformylflustrabromine hydrochloride
CAS :<p>Desformylflustrabromine hydrochloride (dFBr hydrochloride) is a selective agonist of nicotinic acetylcholine receptor (nAChR) in α4β2 neurons, with pEC50 of 6.</p>Formule :C17H12INO5Degré de pureté :98.12%Couleur et forme :SolidMasse moléculaire :437.19Aceclidine
CAS :<p>Aceclidine (1-azabicyclo[2.2.2]octan-3-yl acetate) is a modulator of M3 mAChR and can be used in studies about treating glaucoma by reducing intraocular</p>Formule :C9H15NO2Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :169.22Dimethindene
CAS :<p>Dimethindene (Dimetindeno) is a selective antagonist of H1 receptor and blocks K+ current. Dimethindene exhibits antihistamine and anticholinergic effects.</p>Formule :C20H24N2Degré de pureté :98.3% - 98.99%Couleur et forme :SolidMasse moléculaire :292.42Posatirelin
CAS :<p>Posatirelin, a synthetic peptide, modulates and nourishes brain systems, aiding in vascular dementia research.</p>Formule :C17H28N4O4Degré de pureté :98.08% - 98.87%Couleur et forme :SolidMasse moléculaire :352.43ASM-024
CAS :<p>ASM-024, a synthetic piperazine, activates nicotinic and β2-adrenergic receptors for potential asthma and bronchitis treatment with anti-inflammatory effects.</p>Formule :C15H25N2Degré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :233.37AQW051
CAS :<p>AQW051 (VQW-765) is an oral α7-nAChR activator for cognitive impairments, used in anxiety disorder studies.</p>Formule :C19H22N2ODegré de pureté :99.94%Couleur et forme :SolidMasse moléculaire :294.39Tribendimidine
CAS :<p>Tribendimidine: broad-spectrum oral anthelmintic, nAChR agonist, effective against A. lumbricoides and N. americanus.</p>Formule :C28H32N6Degré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :452.59Oxotremorine M iodide
CAS :<p>Oxotremorine M iodide (Oxotremorine methiodide) is an agonist of mAChR and potentiates NMDA receptors.</p>Formule :C11H19IN2ODegré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :322.19Iperoxo
CAS :<p>Iperoxo (Iperoxo iodide) is an agonist of Muscarinic AChR and can be used to probe activation-related conformational transitions of muscarinic receptors.</p>Formule :C10H17IN2O2Degré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :324.16Xanomeline
CAS :<p>Xanomeline: orally active, M1/M4 selective activator for neurological disorders; promising in trials, crosses blood-brain barrier, liver metabolized.</p>Formule :C14H23N3OSDegré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :281.42NKY80
CAS :<p>NKY80 regulates the adenylyl cyclase catalytic activity in heart and lung tissues.</p>Formule :C12H11N3O2Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :229.23McN-A 343
CAS :<p>McN-A 343: Selective M1 muscarinic agonist; reduces inflammation in colitis models.</p>Formule :C14H18Cl2N2O2Degré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :317.21Thonzylamine hydrochloride
CAS :<p>Thonzylamine hydrochloride (Resistab) is an anticholinergic and antihistamine used as an antipruritic.</p>Formule :C16H23ClN4ODegré de pureté :99.67%Couleur et forme :White Crystalline PowderMasse moléculaire :322.83PF-03635659
CAS :<p>PF-03635659: potent M3 antagonist, Ki=0.2 nM, long half-life, potential COPD treatment.</p>Formule :C28H32N2O3Degré de pureté :98.39% - 99.83%Couleur et forme :SolidMasse moléculaire :444.57CP-810123
CAS :<p>CP-810123 is an α7 nAChR agonist used to treat cognitive deficits associated with psychiatric or neurological disorders such as schizophrenia.</p>Formule :C14H18N4ODegré de pureté :98.63% - 99.60%Couleur et forme :SolidMasse moléculaire :258.32SCH-900271
CAS :<p>SCH-900271 treats dyslipidemia by targeting nicotinic acid receptors, addressing hyperlipidaemia.</p>Formule :C14H16N2O4Degré de pureté :98.82% - 99.93%Couleur et forme :SolidMasse moléculaire :276.29Otenzepad
CAS :Otenzepad (AF-DX 116) is a selective antagonist of M2 mAChR with IC50s of 386 nM and 640 nM for rat heart and rabbit peripheral lung.Formule :C24H31N5O2Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :421.54GSK233705
CAS :<p>GSK233705, a muscarinic antagonist, is used to prevent/treat COPD and asthma.</p>Formule :C24H29BrN2Degré de pureté :99.87% - 99.98%Couleur et forme :SolidMasse moléculaire :425.4Xanomeline oxalate
CAS :<p>Xanomeline oxalate (LY246708), a potent SMRA, boosts phosphoinositide hydrolysis; key for Alzheimer's research.</p>Formule :C16H25N3O5SDegré de pureté :99.1%Couleur et forme :SolidMasse moléculaire :371.45ICL-CCIC-0019
CAS :<p>ICL-CCIC-0019 inhibits ChoKα, causes G1 arrest, ER stress, and cancer cell apoptosis.</p>Formule :C26H44Br2N4Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :572.46APS3
CAS :<p>APS3 is an inhibitor of GABA and nACh receptors, exhibiting an LC50 value of 7.2423 μg/mL against Plutella xylostella [1].</p>Formule :C18H7Cl2F6N5O5S2Couleur et forme :SolidMasse moléculaire :622.31Adenylyl cyclase-IN-1
CAS :<p>Adenylyl cyclase-IN-1 is a potential adenylyl cyclase inhibitor for ocular hypotonia research [1].</p>Formule :C9H8N2S3Couleur et forme :SolidMasse moléculaire :240.37Homatropine hydrochloride
CAS :<p>Homatropine hydrochloride is an orally active anticholinergic agent that induces rapid pupil dilation with cycloplegic effects and possesses antitussive</p>Formule :C16H22ClNO3Couleur et forme :SolidMasse moléculaire :311.8Tiotropium Bromide hydrate
CAS :<p>Tiotropium Bromide hydrate is a potent, long-lasting anticholinergic bronchodilator for COPD, with high affinity for muscarinic receptors M1, M2, and M3.</p>Formule :C19H24BrNO5S2Degré de pureté :98.44% - 99.41%Couleur et forme :SolidMasse moléculaire :490.43PTAC oxalate
CAS :<p>muscarinic receptor ligand</p>Formule :C14H21N3O4S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :359.46mAChR antagonist 1
CAS :<p>Compound 4a, a mAChR antagonist, exhibits K i values of 255 nM for M1 and M5 subtypes, and lower values of 121 nM and 158 nM for M3 and M4 subtypes,</p>Formule :C19H22N2O2Couleur et forme :SolidMasse moléculaire :310.39AR420626
CAS :<p>AR420626: selective FA3R agonist, guards against SALS, effects blocked by BHB, a FA3R antagonist.</p>Formule :C21H18Cl2N2O3Degré de pureté :98.62%Couleur et forme :SolidMasse moléculaire :417.29Muscarine tosylate
CAS :<p>Muscarine ((+)-Muscarine) tosylate, a prototype mAChR agonist, serves as a parasympathetic nervous system stimulant and is recognized for its toxic properties [1] [2].</p>Formule :C16H27NO5SCouleur et forme :SolidMasse moléculaire :345.45Cynandione A
CAS :Cynandione A is an acetophenone derived from Cynanchum wilfordii with anti-inflammatory activity.Formule :C16H14O6Degré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :302.28UFP-512
CAS :<p>UFP-512 is a selective delta-opioid (DOP) receptor agonist.</p>Formule :C31H33N5O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :555.62A-424274
CAS :<p>A-424274 is a positive allosteric modulator of α4β2 neuronal nicotinic receptor.</p>Formule :C14H15N3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :225.29L 687306
CAS :<p>L 687306 is a partial agonist of muscarinic M1 receptors. It is also a highly competitive antagonist at cardiac M2 receptors and ileal M3 muscarinic receptors.</p>Formule :C11H15N3OCouleur et forme :SolidMasse moléculaire :205.26BMS-933043
CAS :<p>BMS-933043: α7 nAChR partial agonist, binds rat (Ki=3.3 nM) & human (Ki=8.1 nM), agonist with EC50=23.4 nM (calcium assay), 0.14-0.29 μM (electrophysiology).</p>Formule :C16H19N7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :325.37VU0453595
CAS :<p>VU0453595 is a M1 positive allosteric modulator (PAM).</p>Formule :C18H15FN4ODegré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :322.343-Bromocytisine
CAS :<p>3-Bromocytisine ((-)-3-Bromocytisine) is an effective agonist of nAChR (IC50s: 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7).</p>Formule :C11H13BrN2ODegré de pureté :99.974%Couleur et forme :SolidMasse moléculaire :269.14LG 50643
CAS :<p>LG 50643 is a muscarinic antagonist.</p>Formule :C24H34INO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :495.44VU 0255035
CAS :<p>VU 0255035 is a highly selective, competitive and brain penetrant muscarinic M1 receptor antagonist with an IC50 of 130 nM.</p>Formule :C18H20N6O3S2Degré de pureté :98.09% - 98.1%Couleur et forme :SolidMasse moléculaire :432.52ABT-418 hydrochloride
CAS :<p>ABT-418 HCl enhances cognition and reduces anxiety as a selective nAChRs agonist, researched for Alzheimer's.</p>Formule :C9H15ClN2OCouleur et forme :SolidMasse moléculaire :202.68Zamifenacin fumarate
CAS :<p>Zamifenacin fumarate (UK-76654 fumarate) is a potent and gut-selective antagonist of muscarinic M3 receptor.</p>Formule :C31H33NO7Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :531.6LY2033298
CAS :<p>LY2033298 enhances oximoline's effect on hamster circadian rhythms, aiding neurosystem disorders.</p>Formule :C13H14ClN3O2SDegré de pureté :99.06%Couleur et forme :SolidMasse moléculaire :311.79Timepidium bromide
CAS :<p>Timepidium bromide is an agent of anticholinergic.</p>Formule :C17H22BrNOS2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :400.4N-Demethyl MK-6884
CAS :<p>N-Demethyl MK-6884 (compound 34) is an M4 mAChR modulator for Alzheimer's and related disease research.</p>Formule :C24H23N5OCouleur et forme :SolidMasse moléculaire :397.47Tematropium
CAS :Tematropium (CDDD3602) possesses anticholinergic effects and can be used in neurological studies.Formule :C21H31NO8SDegré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :457.54Metoquizine
CAS :<p>Metoquizine is an anticholinergic compound. It is a muscarinic acetylcholine receptor antagonist that has been used to treat ulcers.</p>Formule :C22H27N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :377.48LY593093
CAS :<p>LY593093 is a selective partial orthosteric agonist of M1 muscarinic acetylcholine receptor.</p>Formule :C32H30FN3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :507.6TAAR1 agonist 2
CAS :<p>TAAR1 agonist 2 (compound 30), a full agonist at trace amine-associated receptor 1 (TAAR1) (pEC50=7.5), also displays agonistic properties at H1 receptors and activates various muscarinic acetylcholine receptors, including the M2 receptor (pEC50=5). This compound is utilized in researching neuropsychiatric diseases.</p>Formule :C9H11NOCouleur et forme :SolidMasse moléculaire :149.19VU6005806
CAS :<p>VU6005806 is a potent M4 PAM with EC50s: 94 nM (human), 28 nM (rat), 87 nM (dog), 68 nM (cyno); studied for neuropsychiatric disorders.</p>Formule :C17H16F3N7O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :439.41VU6007496
CAS :<p>VU6007496 is a highly selective and CNS-penetrating M1 positive allosteric modulator (PAM) that exhibits good pharmacokinetics (PK).</p>Formule :C25H27N5O2Couleur et forme :SolidMasse moléculaire :429.51WIN 62577
CAS :<p>WIN 62577 is a species-selective tachykinin NK1 receptor antagonist and also serves as an allosteric enhancer with micromolar potency at M3 receptors. Additionally, WIN 62577 demonstrates potent antiviral activity against SARS-CoV-2.</p>Formule :C29H31N3OCouleur et forme :SolidMasse moléculaire :437.5761,9-Dideoxyforskolin
CAS :<p>The compound is an inactive analog of forskolin(an adenylyl cyclase activator).</p>Formule :C22H34O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :378.5Dihydro-β-erythroidine hydrobromide
CAS :<p>Dihydro-β-erythroidine hydrobromide(DHβE) is a potent, oral active and competitive antagonist of neuronal nicotinic acetylcholine receptors (nAChRs).</p>Formule :C16H22BrNO3Degré de pureté :98%Couleur et forme :White SolidMasse moléculaire :356.26(-)-Cevimeline hydrochloride hemihydrate
<p>(-)-Cevimeline HCl hemihydrate, a muscarinic agonist, treats Sjogren's xerostomia. Quick absorption, species-dependent metabolism.</p>Formule :C10H19ClNO1·5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :244.78(+)-Sparteine sulfate pentahydrate
<p>(+)-sparteine (sulfate pentahydrate) is a ganglion blocker that competitively blocks nicotinic acetylcholine receptors in neurons.</p>Formule :C15H38N2O9SCouleur et forme :SolidMasse moléculaire :422.54nAChR antagonist 1
CAS :<p>Compound B15, a potent α7 nAChR antagonist, IC50 = 3.3 μM, promising for research on schizophrenia, Alzheimer's, and inflammation.</p>Formule :C19H22N4O2Couleur et forme :SolidMasse moléculaire :338.4(S)-Albuterol
CAS :<p>(S)-Albuterol functions as a muscarinic receptor and phospholipase C activator, enhancing the intracellular free calcium concentration in airway smooth muscle cells.</p>Formule :C13H21NO3Couleur et forme :SolidMasse moléculaire :239.311Dihydro-β-erythroidine
CAS :<p>Dihydro-β-erythroidine, a competitive nicotinic receptor antagonist, effectively blocks the discriminative stimulus properties and inhibits the anxiolytic</p>Formule :C16H21NO3Couleur et forme :SolidMasse moléculaire :275.34Lu 26-046
CAS :<p>Lu 26-046 is a muscarinic receptor agonist.</p>Formule :C10H12N2OSCouleur et forme :SolidMasse moléculaire :208.28(+)-Cevimeline hydrochloride hemihydrate
<p>(+)-Cevimeline HCl hemihydrate is a muscarinic agonist for dry mouth in Sjogren's with rapid absorption, differing metabolism in species.</p>Formule :C10H19ClNO1·5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :244.78CHF-6366
CAS :<p>CHF-6366: M3 antagonist & β2 agonist (pKi 10.4/11.4), mild Ca channel blocker, used in COPD study.</p>Formule :C42H48N6O8Couleur et forme :SolidMasse moléculaire :764.87UB 165
CAS :<p>Subtype-selective nicotinic agonist</p>Formule :C13H15ClN2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :234.72TDI-11861
CAS :<p>TDI-11861 is a second-gen sAC (ADCY10) inhibitor with an IC50 of 5.5 nM and slow dissociation.</p>Formule :C22H25ClF2N6O3Couleur et forme :SolidMasse moléculaire :494.92VU6016235
CAS :VU6016235 is a structurally unique, orally available, and highly selective tricyclic M4 muscarinic acetylcholine receptor positive allosteric modulator.Formule :C21H22N4OSCouleur et forme :SolidMasse moléculaire :378.49AChE/BChE-IN-10
CAS :<p>AChE/BChE-IN-10 inhibits AChE/BChE (IC50: 0.176/0.47 μM), crosses the blood-brain barrier, and prevents Aβ-aggregation.</p>Formule :C26H30N2O2Degré de pureté :99.55% - 99.88%Couleur et forme :SoildMasse moléculaire :402.53MG 624
CAS :neuronal α7 nAChR antagonistFormule :C22H30INOCouleur et forme :SolidMasse moléculaire :451.38VU6000918
CAS :<p>VU6000918 is a positive allosteric modulator that targets the muscarinic acetylcholine receptor subtype M4. It exhibits a half maximal effective concentration (EC50) of 19 nM for the human M4 receptor.</p>Formule :C18H17F2N5OSCouleur et forme :SolidMasse moléculaire :389.42Lupinine
CAS :<p>Lupinine is an alkaloid capable of counteracting ethanol anesthesia. Lupinine is an AChE and BChE inhibitor and potential CD69 activator found in species of Loranthus, Calia, and Lupinus. It may also inhibit heparin.</p>Formule :C10H19NODegré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :169.26Ref: TM-FR16605
Produit arrêtéOxitropium Bromide
CAS :<p>Oxitropium bromide, a mAChR blocker, treats asthma and COPD as an anticholinergic bronchodilator.</p>Formule :C19H26BrNO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :412.32
