AChR
Les inhibiteurs des récepteurs de l'acétylcholine (AChR) sont des composés qui bloquent l'activité des récepteurs de l'acétylcholine, essentiels pour la neurotransmission dans les systèmes nerveux central et périphérique. Les AChR jouent un rôle crucial dans la contraction musculaire, la mémoire et les fonctions cognitives. Les inhibiteurs des AChR sont utilisés pour étudier des conditions telles que la myasthénie grave, la maladie d'Alzheimer et d'autres troubles neurologiques. En modulant l'activité des AChR, ces inhibiteurs peuvent aider à démêler les complexités de la signalisation cholinergique dans le cerveau. Chez CymitQuimica, nous fournissons une gamme d'inhibiteurs des AChR pour soutenir vos recherches en neurosciences, pharmacologie et maladies neurodégénératives.
617 produits trouvés pour "AChR"
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Anatabine dicitrate
Anatabine dicitrate is a tobacco alkaloid that can cross the blood-brain barrier.Formule :C22H28N2O14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :544.46Flavoxate
CAS :<p>Flavoxate is an anticholinergic with antimuscarinic effects.</p>Formule :C24H25NO4Couleur et forme :SolidMasse moléculaire :391.46(±)-Atropine-d3 (N-methyl-d3)
CAS :(±)-Atropine-d3 (N-methyl-d3) is a deuterated compound of (±)-Atropine. (±)-Atropine has a CAS number of 51-55-8. Atropine Sulfate is the sulfate salt of atropine, a naturally-occurring alkaloid isolated from the plant Atropa belladonna. Atropine functions as a sympathetic, competitive antagonist of muscarinic cholinergic receptors, thereby abolishing the effects of parasympathetic stimulation.Formule :C17H20D3NO3Masse moléculaire :292.39Diphenidol
CAS :<p>Diphenidol, a muscarinic antagonist, is employed as an antivertigo and antiemetic agent.</p>Formule :C21H27NOCouleur et forme :Needles From Petroleum Ether SolidMasse moléculaire :309.45VU0029767
CAS :<p>VU0029767 is an allosteric enhancer of the M1 muscarinic receptor, capable of modulating the receptor's activity. This compound enhances M1 receptor activity by increasing agonist affinity. However, VU0029767 demonstrates distinct characteristics from other compounds, particularly under varying experimental conditions such as its interaction with mutated M1 receptors and its effects on downstream signaling pathways.</p>Formule :C21H21N3O3Couleur et forme :SolidMasse moléculaire :363.41Catestatin
CAS :Non-competitive inhibitor of nicotinic receptors; blocks cationic signalling and catecholamine release; stimulates histamine release. IC50 ~200-250nM.Formule :C107H173N37O26SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :2425.84N-Biotinyl p-aminophenyl arsenic acid
CAS :N-Biotinyl p-aminophenyl arsenic acid is a bifunctional reagent that binds to streptavidin and disulfide compounds. It diminishes the binding sites of rbungarotoxin on reduced nicotinic receptors with an IC50 ranging from 10-300 nM, thus shielding the receptors from irreversible alkylation by bromoacetylcholine.Formule :C16H22AsN3O4SCouleur et forme :SolidMasse moléculaire :427.35Phenglutarimide hydrochloride
CAS :Phenglutarimide hydrochloride is an anticholinergic. It is used as an antiparkinsonian agent.Formule :C17H25ClN2O2Couleur et forme :SolidMasse moléculaire :324.85Aprofene
CAS :<p>Aprofene blocks acetylcholine receptors, used for peptic ulcers, endarteritis, cholecystitis, and colitis.</p>Formule :C21H27NO2Couleur et forme :SolidMasse moléculaire :325.44Dianicline dihydrochloride
CAS :Dianicline dihydrochloride is a partial agonist of α4β2 nicotinic acetylcholine receptor. It increases cessation rates in a dose-dependent manner.Formule :C13H16N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :216.28Biperiden lactate
CAS :<p>Biperiden lactate is a biochemical.</p>Formule :C24H35NO4Couleur et forme :SolidMasse moléculaire :401.54AN317
CAS :AN317 is a selective agonist for the nicotinic acetylcholine receptor (nAChR) containing α6β2, with dissociation constants (Ki) of 6.2 nM and 4.1 nM for the α6/α3β2β3 and α4β2 receptor subtypes, respectively. It induces dopamine release in rat striatal synaptosomes, enhances the activity of dopaminergic neurons in the substantia nigra, and exhibits protective effects against the dopaminergic neurotoxin MPP+ in rat neurons. AN317 also demonstrates favorable pharmacokinetic properties in rats and permeability across the blood-brain barrier (BB).Formule :C13H19N3Couleur et forme :SolidMasse moléculaire :217.31Azacyclonol hydrochloride
CAS :Azacyclonol hydrochloride can be used in the treatment of chronic schizophrenia.Formule :C18H22ClNOCouleur et forme :Off White Crystalline PowderMasse moléculaire :303.83Oxantel
CAS :<p>Oxantel is a fumarate reductase inhibitor with anthelmintic activity.</p>Formule :C13H16N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :216.28Sulindac sulfide
CAS :Sulindac sulfide: NSAID targeting COX-1, inhibits Ras-Raf-1 and gamma-secretase (IC50: 20.2 μM), active sulinic acid metabolite.Formule :C20H17FO2SDegré de pureté :99.35%Couleur et forme :SolidMasse moléculaire :340.41BTM-1086
CAS :BTM-1086 is a potent gastric secretory inhibitor and an anti-ulcer agent.Formule :C21H25N3OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :367.51CP-601932
CAS :CP-601932 (free base) is a selective base α( 4) β( 2) Nicotinic acetylcholine receptor agonist.Formule :C12H12F3NCouleur et forme :SolidMasse moléculaire :227.23Eucatropine
CAS :Eucatropine, an anticholinergic agent, acts as a potent inhibitor of the muscarinic acetylcholine receptor (mAChR) with an IC 50 value of 0.583 μM.Formule :C17H25NO3Couleur et forme :SolidMasse moléculaire :291.39Thiochrome
CAS :Thiochrome is a selective enhancer of M4 muscarinic receptor of acetylcholine (ACh) affinity.Formule :C12H14N4OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :262.33GAT107
CAS :GAT107, a strong α7 nicotinic receptor modulator, aids inflammation and neuropathic pain in mice.Formule :C18H17BrN2O2SDegré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :405.31
