Sérine protéase
Les inhibiteurs de protéases à sérine sont des composés qui ciblent et inhibent les protéases à sérine, un groupe d'enzymes caractérisées par un résidu de sérine dans leur site actif. Ces protéases sont impliquées dans de nombreux processus physiologiques, notamment la digestion, la réponse immunitaire, la coagulation sanguine et l'inflammation. Les inhibiteurs de protéases à sérine sont essentiels pour étudier les maladies où ces enzymes sont dysrégulées, telles que les maladies cardiovasculaires, le cancer et les affections inflammatoires. Chez CymitQuimica, nous proposons des inhibiteurs de protéases à sérine pour soutenir vos recherches en enzymologie, mécanismes des maladies et interventions thérapeutiques.
50 produits trouvés pour "Sérine protéase"
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TAO Kinase inhibitor 2
CAS :<p>TAO Kinase inhibitor 2 is a TAO kinase inhibitor with an IC50 of 50-500 nM. TAO Kinase inhibitor 2 inhibits KIAA1361 and JIK with IC50s of 50-500 nM.</p>Formule :C25H24N2O3Degré de pureté :98.58%Couleur et forme :SoildMasse moléculaire :400.47BAY-85-8501
CAS :<p>BAY-85-8501 is a selective, reversible and potent inhibitor of Human Neutrophil Elastase (HNE; IC50 of 65 pM)</p>Formule :C22H17F3N4O3SDegré de pureté :99.16%Couleur et forme :SolidMasse moléculaire :474.46PMSF
CAS :<p>PMSF (Phenylmethylsulfonyl fluoride) is an irreversible inhibitor of serine/cysteine protease , preparation of cell lysates. High-Quality, Low-Cost!</p>Formule :C7H7FO2SDegré de pureté :97.75% - 99.88%Couleur et forme :White To Cream SolidMasse moléculaire :174.19Tilpisertib fosmecarbil TFA
CAS :Tilpisertib fosmecarbil TFA, the TFA salt form of Tilpisertib, acts as an inhibitor of serine/threonine kinases. This compound also exhibits anti-inflammatory activity.Formule :C37H37ClF3N8O9PCouleur et forme :SolidMasse moléculaire :861.16Ala-Phe-Pro-pNA TFA
<p>Ala-Phe-Pro-pNA TFA serves as a chromogenic substrate for tripeptidyl peptidase and can be utilized to assess the enzyme's activity.</p>Couleur et forme :Odour SolidBCX 1470 hydrochloride
<p>BCX 1470 hydrochloride is a serine protease inhibitor with anti-inflammatory activity that inhibits factor D hemolytic activity and may be used to study edema.</p>Formule :C14H11ClN2O2S2Degré de pureté :99.71%Couleur et forme :SoildMasse moléculaire :338.83Protease Inhibitor Library
<p>A unique collection of 343 protease and proteasome inhibitors for research in chemical genomics, and drug screening;</p>Couleur et forme :Odour SolidKKI-5
CAS :<p>KKI 5: Serine protease inhibitor, blocks kallikrein & plasmin, potential for cancer therapy & angioedema treatment.</p>Formule :C35H55N11O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :773.88AE-3763
CAS :<p>AE-3763 is a peptide-based human neutrophil elastase inhibitor (IC50: 29 nM).</p>Formule :C23H34F3N5O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :549.54Patamostat HCl
CAS :<p>Patamostat HCl is a highly potent and selective small molecule protease (protease) inhibitor that inhibits trypsin, fibrinolytic enzymes, and thrombin with IC50</p>Formule :C20H21ClN4O4SDegré de pureté :99.15% - 99.76%Couleur et forme :SoildMasse moléculaire :448.92MeOSuc-AAPA-CMK
MeOSuc-AAPA-CMK is a potent inhibitor of human neutrophil elastase (HNE) [1].Formule :C20H31ClN4O8Couleur et forme :SolidMasse moléculaire :490.94α 1 Antichymotrypsin, Human Plasma
CAS :<p>Alpha 1 Antichymotrypsin, Human Plasma is an inhibitor of serine proteases. This compound is present in amyloid lesions associated with Alzheimer's disease and can be utilized in Alzheimer's research.</p>Couleur et forme :SolidRoseltide rT1
CAS :<p>Roseltide rT1 is a neutrophil elastase inhibitor (IC50=0.47 μM) and is rich in cysteine, classified as one of the Roseltides (rT1-rT8). It has the potential to inhibit related diseases by improving neutrophil elastase-stimulated cAMP accumulation in vitro.</p>Formule :C110H177N31O31S6Couleur et forme :SolidMasse moléculaire :2622.16Lonodelestat TFA
<p>Lonodelestat TFA, an oral peptide, selectively inhibits hNE, potentially aiding in CF research.</p>Formule :C73H112F3N15O21Couleur et forme :SolidMasse moléculaire :1592.75Tiprelestat
CAS :<p>Tiprelestat: strong inhibitor of human neutrophil elastase, anti-inflammatory, antimicrobial, used in inflammation/immune research.</p>Formule :C254H416N72O75S10Couleur et forme :SolidMasse moléculaire :5999.09α-Methyl-DL-aspartic acid
CAS :<p>α-Methyl-DL-aspartic acid specifically inhibits argininosuccinate synthase (ASS), the rate-limiting enzyme in 1-citrulline-to-1-arginine recycling.</p>Formule :C5H9NO4Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :147.13Recombinant Trypsin
<p>Recombinant Trypsin is a serine protease that hydrolyzes proteins at the carboxyl side of lysine or arginine.</p>Dansyl-Glu-Gly-Arg-Chloromethylketone
CAS :Dansyl-Glu-Gly-Arg-Chloromethylketone is a protease inhibitor that specifically impedes serine/threonine proteases and has been shown to inhibit activatedFormule :C26H36ClN7O7SCouleur et forme :SolidMasse moléculaire :626.12Suc-AAP-Abu-pNA
CAS :<p>Suc-AAP-Abu-pNA is a specific substrate for pancreatic elastase (Km = 100 μM; Kcat/Km = 35,300 s-1 M-1 for rat pancreatic elastase; Km = 30 μM; Kcat/Km = 351,</p>Formule :C25H34N6O9Couleur et forme :SolidMasse moléculaire :562.57SFTI-1
CAS :SFTI-1, a cyclic peptide trypsin inhibitor comprising 14 amino acid residues, is a potent Bowman-Birk inhibitor.Formule :C67H104N18O18S2Couleur et forme :SolidMasse moléculaire :1513.78Chymotrypsinogen
CAS :<p>Chymotrypsinogen is an inactive precursor of Chymotrypsin . Chymotrypsin is a serine protease produced by the pancreas [1] [2] .</p>Couleur et forme :SolidPKR-IN-C51
CAS :<p>PKR-IN-C51 is ATP-competitive protein kinase R (PKR) inhibitor that inhibits intracellular PKR activation and autophosphorylation. Ser/Thr kinase.</p>Formule :C23H21N5Degré de pureté :98.94%Couleur et forme :SolidMasse moléculaire :367.45Urokinase
CAS :<p>Urokinase (uPA) is a serine protease that activates plasminogen to plasmin, crucial for thrombolysis and ECM degradation.</p>Couleur et forme :SolidGSK-690693
CAS :<p>GSK-690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. Phase 1.</p>Formule :C21H27N7O3Degré de pureté :98.07% - 99.77%Couleur et forme :SolidMasse moléculaire :425.482-(2-bromophenyl)-5-chloro-4H-3,1-benzoxazin-4-one
CAS :<p>2-(2-bromophenyl)-5-chloro-4H-3,1-benzoxazin-4-one is an human neutrophil elastase inhibitor.</p>Formule :C14H7BrClNO2Degré de pureté :97.36%Couleur et forme :SolidMasse moléculaire :336.57Cetraxate hydrochloride
CAS :<p>Cetraxate hydrochloride (DV10062) is an oral gastrointestinal medication. It has a cytoprotective effect.</p>Formule :C17H24ClNO4Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :341.83WNK463
CAS :<p>WNK463 is a pan-WNK-kinase inhibitor. It effectively inhibits the in vitro kinase activity of all four WNK family members (WNK1/2/3/4).</p>Formule :C21H24F3N7O2Degré de pureté :>99.99% - ≥95%Couleur et forme :SolidMasse moléculaire :463.46WNK-IN-11
CAS :<p>WNK-IN-11 (Allosteric WNK Kinase Inhibitor) is an allosteric With-No-Lysine (WNK) kinase inhibitor,WNK1(IC50 : 4 nM)</p>Formule :C21H21Cl2N5OSDegré de pureté :98.32%Couleur et forme :SolidMasse moléculaire :462.4Alvelestat
CAS :<p>Alvelestat (AZD9668) is an orally bioavailable, selective and reversible inhibitor of human neutrophil elastase (NE), with potential anti-inflammatory activity.</p>Formule :C25H22F3N5O4SDegré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :545.53ML281
CAS :<p>ML281 is a potent and selective STK33 inhibitor with IC50 of 14 nM.</p>Formule :C22H19N3O2SDegré de pureté :99.12% - 99.87%Couleur et forme :SolidMasse moléculaire :389.472,4-Dioxaspiro(5.5)undec-8-ene, 3-(2-furanyl)-
CAS :<p>2,4-Dioxaspiro(5.5)undec-8-ene, 3-(2-furanyl)- (Ulinastatin) ,as an urinary trypsin inhibitor (UTI), is a glycoprotein that is isolated from healthy human urine</p>Formule :C13H16O3Degré de pureté :99.53% - 99.81%Couleur et forme :SolidMasse moléculaire :220.26Ceritinib
CAS :<p>Ceritinib (LDK378) is an ALK inhibitor with selective, ATP-competitive, and oral activity. Ceritinib has antitumor activity. Cost-effective and quality-assured.</p>Formule :C28H36ClN5O3SDegré de pureté :98.52% - 99.77%Couleur et forme :SolidMasse moléculaire :558.14Lanadelumab
CAS :<p>Lanadelumab (SHP643), a humanized IgG1 antibody, inhibits plasma kallikrein and its interaction with HMWK, supporting hereditary angioedema research.</p>Degré de pureté :95% - 95%Couleur et forme :LiquidGalegenimab
CAS :<p>Galegenimab (FHTR 2163; RG 6147; RO 7171009) is an HTRA1 antibody fragment for AMD research.</p>Degré de pureté :95% - 95%Couleur et forme :LiquidMEGA-9
CAS :<p>MEGA-9 (Nonanoyl-N-Methylglucamide) solubilizes membrane protein and can be used as a nonionic detergent.</p>Formule :C16H33NO6Degré de pureté :99.9%Couleur et forme :SolidMasse moléculaire :335.44BMS-363131
CAS :<p>BMS-363131 (BMS363131) is a potent and selective trypsin inhibitor with an IC50 value of <1.7 nM.</p>Formule :C28H40N6O5Degré de pureté :97.99%Couleur et forme :SolidMasse moléculaire :540.65p-Aminobenzamidine dihydrochloride
CAS :<p>4-Aminobenzamidine dihydrochloride (p-Aminobenzamidine dihydrochloride) is a strong trypsin inhibitor and a relatively weak inhibitor of urokinase type</p>Formule :C7H11Cl2N3Degré de pureté :99.00% - 99.56%Couleur et forme :SolidMasse moléculaire :208.088ZD8321
CAS :<p>ZD8321 is an effective inhibitor of human Neutrophil elastase (Ki: 13±1.7 nM).</p>Formule :C18H28F3N3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :423.43ZD-0892
CAS :<p>ZD-0892: potent, selective neutrophil elastase inhibitor; Ki 6.7 nM (human), 200 nM (porcine).</p>Formule :C24H32F3N3O5Degré de pureté :95% - 99.53%Couleur et forme :SolidMasse moléculaire :499.52APC 366
CAS :<p>APC 366: Mast cell tryptase inhibitor, Ki 7.1 μM. Reduces EAR, LAR, BHR in allergic asthma (sheep model).</p>Formule :C22H28N6O4Degré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :440.5ZM223 hydrochloride (2031177-48-5 free base)
<p>ZM223 hydrochloride is an orally active, potent non-covalent inhibitor of NEDD8 activating enzyme (NAE), and with excellent anticancer activity.</p>Formule :C23H18ClF3N4O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :538.99AGLME
CAS :<p>AGLME is used in a direct enzymatic assay for activated Hageman factor measuring the ability of Hageman factor to hydrolyze the cpd.</p>Formule :C11H21N3O4Couleur et forme :SolidMasse moléculaire :259.3WNK1-IN-1
CAS :<p>WNK1-IN-1, a WNK1 inhibitor (IC50: 1.6 μM), also inhibits OSR1 phosphorylation (IC50: 4.3 μM), used in blood pressure and cancer research.</p>Formule :C13H15BrCl2N2O4SDegré de pureté :98.09%Couleur et forme :SolidMasse moléculaire :446.14IPR-803
CAS :<p>IPR-803 is an effective inhibitor of the uPAR·uPA protein-protein interaction (PPI) with anti-tumor activity.</p>Formule :C27H23N3O4Degré de pureté :95%Couleur et forme :SolidMasse moléculaire :453.49FK706
CAS :<p>FK706, a human neutrophil elastase inhibitor (IC50: 83 nM, Ki: 4.2 nM), also blocks mouse and porcine elastases. Anti-inflammatory.</p>Formule :C26H33F3N4NaO7Couleur et forme :SolidMasse moléculaire :593.556LM-030
CAS :<p>LM-030, also known as BPR277, is a novel inhibitor of kallikrein-related peptidase 7 (KLK7) and epidermal elastase 2 (ELA2).</p>Formule :C46H72N8O12Couleur et forme :SolidMasse moléculaire :929.11Feniralstat
CAS :<p>Feniralstat (KVD-824) is a selective and potent kallikrein (kallikrein) inhibitor, useful in immune system diseases and cardiovascular disease research.</p>Formule :C26H25F2N5O4Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :509.51Matriptase-IN-2 free base
CAS :<p>Matriptase-IN-2 free base, a matriptase inhibitor with a K i of 5 nM, has potential applications in musculoskeletal system disorder research (WO2011023958A1; compound 432) [1].</p>Formule :C29H33Cl2N5O3SCouleur et forme :SolidMasse moléculaire :602.58TMPRSS6-IN-1 TFA
<p>TMPRSS6-IN-1 (TFA) is a potent inhibitor of TMPRSS6 (Matriptase-2), a member of the TTSP family (a type of transmembrane serine protease). TMPRSS6 is a type II TTSP, and genetically reduced levels of TMPRSS6 have been shown to improve symptoms of hemochromatosis and β-thalassemia in mice.</p>Formule :C35H41F3N8O6S2Couleur et forme :SolidMasse moléculaire :790.875MeO-Suc-Ala-Ala-Pro-Ala-CMK
CAS :<p>MeO-Suc-Ala-Ala-Pro-Ala-CMK (MSACK) is an inhibitor of human neutrophil elastase (HNE) with an IC50 of 20.3 μM. It effectively inhibits the hydrolysis of substrates like lung tissue elastin by HNE and is applicable in studies related to conditions such as chronic obstructive pulmonary disease (COPD).</p>Formule :C20H31ClN4O7Couleur et forme :SolidMasse moléculaire :474.936
