PAI-1
Le Plasminogen Activator Inhibitor-1 (PAI-1) est un inhibiteur de la sérine protéase qui régule la fibrinolyse en inhibant l'activateur tissulaire du plasminogène (tPA) et l'urokinase (uPA). Des niveaux élevés de PAI-1 sont associés à un risque accru de thrombose, de maladies cardiovasculaires et de syndrome métabolique. Les inhibiteurs de PAI-1 font l'objet de recherches pour leur potentiel dans le traitement de ces conditions. Chez CymitQuimica, nous proposons des inhibiteurs de PAI-1 pour soutenir vos recherches en hématologie, santé cardiovasculaire et maladies métaboliques.
25 produits trouvés pour "PAI-1"
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Upamostat
CAS :<p>Upamostat is an inhibitor of a serine protease and is a urokinase plasminogen activator (uPA) inhibitor.</p>Formule :C32H47N5O6SDegré de pureté :99.41%Couleur et forme :SolidMasse moléculaire :629.81Angstrom6
CAS :<p>Angstrom6 (A-6 peptide) is an 8 amino acid peptide derived from single chain urokinase fibrinogen activator (scuPA) that interferes with the uPA/uPAR cascade</p>Formule :C39H62N10O15Degré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :910.97CT140
<p>CT140 is a human IgG4 monoclonal antibody (mAb) that specifically targets PAI-1. The suggested isotype control for this compound is Human IgG4 kappa, Isotype Control.</p>Couleur et forme :Odour LiquidGGACK hydrochloride
<p>GGACK (H-Glu-Gly-Arg-CMK) hydrochloride is an irreversible substrate-like inhibitor of the serine protease urokinase-type plasminogen activator (uPA).</p>Formule :C14H26Cl2N6O5Couleur et forme :SolidMasse moléculaire :428.13417Nattokinase
CAS :<p>Nattokinase is a serine protease derived from nattō, oral， fibrinolytic/anticoagulant properties. It degrades fibrin, fibrinolytic substrates, and PAI-1.</p>Couleur et forme :SolidUK140
<p>UK140 is an inhibitor of the urokinase-type plasminogen activator (uPA), with Ki values of 0.20 µM for human uPA (huPA) and 2.79 µM for mouse uPA (muPA). UK140 is applicable in studies related to tumor metastasis.</p>Formule :C72H105N19O25S3Couleur et forme :SolidMasse moléculaire :1732.91Bicyclic UK18
CAS :<p>Bicyclic UK18 is a competitive inhibitor of human urokinase-type plasminogen activator (uPA) with a Ki value of 53 nM.</p>Formule :C77H118N26O25S3Couleur et forme :SolidMasse moléculaire :1904.11UK-371804
CAS :<p>UK-371804: potent uPA blocker; candidate for chronic skin ulcer preclinical studies.</p>Formule :C14H16ClN5O4SDegré de pureté :95.81% - 99.77%Couleur et forme :SolidMasse moléculaire :385.83Loureirin B
CAS :<p>Loureirin B suppresses fibrosis by modulating MMPs/TIMPs, hindering fibroblast growth, and targeting TGF-β1/Smad2/3 pathway.</p>Formule :C18H20O5Degré de pureté :99.33% - 99.86%Couleur et forme :SolidMasse moléculaire :316.35TM5441
CAS :<p>TM5441 is an orally bioavailable fibrinogen activator inhibitor-1 inhibitor that inhibits several cancer cell lines with IC50 values ranging from 13.9 to 51.1 μM.Cost-effective and quality-assured.Cost-effective and quality-assured.</p>Formule :C21H17ClN2O6Degré de pureté :97.62% - 99.09%Couleur et forme :SolidMasse moléculaire :428.82TM5007
CAS :<p>TM5007 is a poent inhibitor of plasminogen activator inhibitor-1 (PAI-1; IC50 of 29 uM).</p>Formule :C24H20N2O6S4Degré de pureté :96.91%Couleur et forme :SolidMasse moléculaire :560.69Tiplaxtinin
CAS :<p>Tiplaxtinin (Tiplasinin)(PAI-039) is a selective and orally efficacious inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 2.7 uM.</p>Formule :C24H16F3NO4Degré de pureté :99.16% - 99.93%Couleur et forme :SolidMasse moléculaire :439.38Toddalolactone
CAS :<p>Toddalolactone ((+)-Toddalolactone) is an anti-inflammatory and analgesic.</p>Formule :C16H20O6Degré de pureté :99.06% - 99.85%Couleur et forme :SolidMasse moléculaire :308.33TM5275 sodium
CAS :<p>TM5275 sodium (TM5275 sodium salt) is an inhibitor of plasminogen activator inhibitor 1 (PAI-1).</p>Formule :C28H27ClN3NaO5Degré de pureté :98.8% - 99.74%Couleur et forme :SolidMasse moléculaire :543.98MDI-2268
CAS :<p>MDI-2268, an inhibitor of plasma kallikrein inhibitor 1 (PAI-1), exhibits strong antithrombotic properties. It plays a role in regulating blood coagulation by promoting fibrinolysis and is applicable in research related to deep vein thrombosis.</p>Formule :C10H10F3N3O3Couleur et forme :SolidMasse moléculaire :277.20SK-216
CAS :<p>SK-216,PAI-1 inhibitor. Reduces tumor angiogenesis. Inhibits VEGF-induced endothelial cell migration. Alleviates pulmonary fibrosis.</p>Formule :C29H29NNa2O6Degré de pureté :98.29%Couleur et forme :SolidMasse moléculaire :533.52UK-371804 HCl
CAS :<p>UK-371804 is a potent and selective urokinase-type plasmogen activator (uPA) inhibitor with excellent enzyme potency (Ki=10 nM) and selectivity profile (2700-</p>Formule :C14H17Cl2N5O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :422.29Diaplasinin
CAS :<p>Diaplasinin (PAI-749) is a potent inhibitor of plasminogen activator inhibitor-1 (PAI-1) with antithrombotic activity, used in cardiovascular disease research.</p>Formule :C32H31N5ODegré de pureté :99.02%Couleur et forme :SolidMasse moléculaire :501.62Aleplasinin
CAS :<p>Aleplasinin (PAZ 417) is a selective and orally active inhibitor of Plasminogen activator inhibitor-1(PAI-1) and a key negative regulator of the fibrinolytic</p>Formule :C28H27NO3Degré de pureté :99.21%Couleur et forme :SolidMasse moléculaire :425.52AZ3976
CAS :<p>AZ3976 is an inhibitor of PAI-1 with an IC50 of 16 μM in a plasma clot lysis assay. AZ3976 displays profibrinolytic activities.</p>Formule :C15H19N5O3Degré de pureté :98.14%Couleur et forme :SolidMasse moléculaire :317.34PPACK
CAS :<p>PPACK: synthetic peptide, irreversibly inhibits thrombin (Ki = 0.24 nM), prevents platelet activation.</p>Formule :C21H31ClN6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :450.96GW-6604
CAS :<p>GW-6604 is an ALK5 inhibitor and shows clear antifibrotic effects resulting in liver function improvement.</p>Formule :C19H14N4Degré de pureté :99.6%Couleur et forme :SolidMasse moléculaire :298.34ZK824190
CAS :<p>ZK824190: oral uPA inhibitor, IC50 - uPA 237 nM, tPA 1600 nM, Plasmin 1850 nM.</p>Formule :C22H20F2N2O4Degré de pureté :98.84%Couleur et forme :SolidMasse moléculaire :414.4BT-114143
CAS :<p>BT-114143 is a plasminogen activator inhibitor with an IC50 of 8.42 μM. It is applicable in research related to hemorrhagic diseases caused by excessive fibrinolysis, including traumatic bleeding, severe menorrhagia, postpartum hemorrhage, and complications of hemophilia.</p>Formule :C8H11N2O3PCouleur et forme :SolidMasse moléculaire :214.158GGACK
CAS :<p>GGACK (H-Glu-Gly-Arg-CMK) is an irreversible substrate-like inhibitor of the serine protease urokinase-type plasminogen activator (uPA).</p>Formule :C14H25ClN6O5Masse moléculaire :392.84
