Cystéine protéase
Les inhibiteurs de protéases à cystéine sont des composés qui ciblent et inhibent les protéases à cystéine, une classe d'enzymes qui décomposent les protéines en clivant les liaisons peptidiques dans lesquelles un résidu de cystéine agit comme nucléophile. Ces enzymes sont impliquées dans divers processus physiologiques, tels que l'apoptose, la réponse immunitaire et le renouvellement des protéines. Les inhibiteurs de protéases à cystéine sont essentiels pour l'étude de maladies telles que le cancer, les troubles neurodégénératifs et les infections parasitaires. Chez CymitQuimica, nous fournissons des inhibiteurs de protéases à cystéine pour soutenir vos recherches en protéolyse, régulation cellulaire et découverte de médicaments.
117 produits trouvés pour "Cystéine protéase".
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BI-1915
CAS :BI-1915 is a selective inhibitor of Cathepsin S, with an IC50 of 17 nM. It is utilized in the research of autoimmune diseases.Formule :C21H37N5O3Couleur et forme :SolidMasse moléculaire :407.55Cathepsin C-IN-3
Cathepsin C-IN-3 is a potent inhibitor of histone C (IC50: 61.79 nM) and also inhibits THP-1 cells (IC50: 101.5 nM) and U937 cells (IC50: 86.5 nM).Formule :C28H21F3N6OSCouleur et forme :SolidMasse moléculaire :546.57RO5461111
CAS :RO5461111: Oral Cathepsin S inhibitor, IC50 of 0.4 nM (human) & 0.5 nM (mouse), reduces T/B cell activation, treats lung inflammation & lupus nephritis.Formule :C27H24F6N4O4SCouleur et forme :SolidMasse moléculaire :614.56SID 26681509 quarterhydrate
SID 26681509 is a selective inhibitor of cathepsin L (IC50: 56 nM) and blocks Plasmodium falciparum (IC50: 15.4 μM) and Leishmania major (IC50: 12.5 μM).Formule :C27H35N5O6SCouleur et forme :SolidMasse moléculaire :544.16Z-Val-Val-Nle-diazomethylketone
CAS :Z-Val-Val-Nle-diazomethylketone is an inhibitor of cathepsin S (CATS). It significantly suppresses the upregulation of IFNg-induced MHCII molecules, specifically HLA-DR and Ii-p33/35, while increasing the protein level of Ii-p10. This compound can be utilized for research into skin disorders such as psoriasis, atopic dermatitis, and actinic keratosis.Formule :C25H37N5O5Couleur et forme :SolidMasse moléculaire :487.59Dual Cathepsin L/JAK-IN-1
CAS :DualCathepsinL/JAK-IN-1 (Compound A8) serves as a dual inhibitor of Cathepsin L (CTSL) and JAK, exhibiting IC50 values of 0.68 μM for CTSL and 337.1 nM, 5.251 nM, 27.29 nM, and 172.6 nM for JAK1/2/3 and TYK2, respectively. This compound effectively prevents the activation of MAPK, NF-κB, and JAK/STAT signaling pathways, leading to significant anti-inflammatory therapeutic effects. DualCathepsinL/JAK-IN-1 is applicable in research on acute lung injury (ALI).Formule :C19H18ClN5Couleur et forme :SolidMasse moléculaire :351.833ONO-5334
CAS :ONO-5334: selective cathepsin K inhibitor, potential for osteoporosis study; Ki: 0.10 nM (human), 0.049 nM (rabbit), 0.85 nM (rat).Formule :C21H34N4O4SDegré de pureté :98.22% - 99.60%Couleur et forme :SolidMasse moléculaire :438.58Cathepsin K-IN-8
CAS :CathepsinK-IN-8 (cxample 6-60) is an inhibitor of cathepsin K, which is useful for researching inflammation, rheumatoid arthritis, osteoarthritis, osteoporosis, and tumors.Formule :C25H32N6O2Masse moléculaire :448.56AEP-IN-1
APE-IN-1, a potent AEP inhibitor (IC50: 89 nM), aids Alzheimer's diagnosis and drug research.Formule :C18H27N3O3Couleur et forme :SolidMasse moléculaire :333.43SAR-114137
CAS :SAR-114137 is a histone sphingomyelin kinase inhibitor used in the study of molluscum arteriosum and peripheral neuropathic pain.Formule :C25H34N4O7SDegré de pureté :99.09% - 99.91%Couleur et forme :SolidMasse moléculaire :534.63Cathepsin C-IN-5
CAS :Cathepsin C-IN-5 (SF38) is a potent, oral Cathepsin C blocker with an IC50 of 59.9 nM; less active against Cat L/S/B/K; has anti-inflammatory effects.Formule :C21H17ClN6OSCouleur et forme :SolidMasse moléculaire :436.92AEP-IN-3
CAS :AEP-IN-3 (compound 18) is an orally administered, potent asparagine endopeptidase (AEP) inhibitor that effectively crosses the blood-brain barrier. It boasts an IC50 of 7.8 ± 0.9 nM and is applicable in Alzheimer's Disease (AD) research [1].Formule :C21H21F4N3O4Masse moléculaire :455.4Z-FY-CHO
CAS :Pyridoxal (Pyridoxaldehyde), a component of vitamin B6, is an aldehyde obtained by oxidizing pyridoxine and is widely found in plants and animals.Formule :C26H26N2O5Degré de pureté :95.88%Couleur et forme :SolidMasse moléculaire :446.5GB111-NH2
CAS :GB111-NH2, a cysteine cathepsin inhibitor, is applicable in cancer research [1].Formule :C33H39N3O6Couleur et forme :SolidMasse moléculaire :573.68Verducatib
CAS :Verducatib is an inhibitor of cathepsins (cathepsin).Formule :C31H35FN4O3Couleur et forme :SolidMasse moléculaire :530.633MIV-247
CAS :MIV-247 is a cathepsin S inhibitor that attenuates mechanically abnormal pain in preclinical neuropathic pain models and can be used to study myocardial injury.Formule :C17H24F3N3O4Degré de pureté :99.27%Couleur et forme :SolidMasse moléculaire :391.39PD 151746
CAS :PD151746: calpain inhibitor, Ki μ-calpain=0.26μM, Ki m-calpain=5.33μM; reduces oxLDL cytotoxicity.Formule :C11H8FNO2SDegré de pureté :98.63% - ≥95%Couleur et forme :Yellow SolidMasse moléculaire :237.25
