DPP-4
Les inhibiteurs de DPP-4 sont des composés qui inhibent la Dipeptidyl Peptidase-4, une enzyme impliquée dans l'inactivation des hormones incrétines, qui régulent le métabolisme du glucose. En inhibant la DPP-4, ces composés prolongent l'action des hormones incrétines, augmentant la sécrétion d'insuline et réduisant les niveaux de glucose dans le sang. Les inhibiteurs de DPP-4 sont largement utilisés dans le traitement du diabète de type 2 et dans les recherches axées sur les troubles métaboliques. Chez CymitQuimica, nous proposons des inhibiteurs de DPP-4 pour soutenir vos recherches en endocrinologie, gestion du diabète et maladies métaboliques.
94 produits trouvés pour "DPP-4".
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H-Gly-Pro-Hyp-OH acetate
CAS :H-Gly-Pro-Hyp-OH, a peptide dipeptidyl peptidase 4 (DPP-4) inhibitor with an inhibition concentration (IC50) of 2.51 mM, effectively hinders the activity of the DPP-4 enzyme.Formule :C14H23N3O7Couleur et forme :SolidMasse moléculaire :345.3483O-Benzoylhydroxylamine
CAS :O-Benzoyl hydroxylamine exhibits properties as a dipeptidyl peptidase-IV (DPP-IV) inhibitor and demonstrates antidiabetic effects[1].Formule :C7H7NO2Couleur et forme :SolidMasse moléculaire :137.14ASP-8497
CAS :ASP8497 is a potent DPP-IV inhibitor enhancing GLP-1, used for type 2 diabetes and glucose intolerance.Formule :C18H27FN4O7SCouleur et forme :SolidMasse moléculaire :462.49γ-Glu-Tyr
CAS :gamma-Glu-Tyr (gamma-Glutamyltyrosine) is a kokumi peptide against dipeptidyl peptidase-IV (DPP-IV) and is used in the study of diabetes mellitus.Formule :C14H18N2O6Degré de pureté :98.92%Couleur et forme :SolidMasse moléculaire :310.3RBx-0597
CAS :RBx-0597 is a selective DPP-IV inhibitor with IC50 values of 32 nM, 31 nM, and 39 nM for human, mouse, and rat plasma DPP-IV, respectively. It is utilized in research focused on type 2 diabetes.Formule :C19H20F2N4O2Couleur et forme :SolidMasse moléculaire :374.384ZINC000003015356
CAS :ZINC000003015356 acts as a DPP4 inhibitor [1].Formule :C25H25N3O5Masse moléculaire :447.4831ZY15557
CAS :ZY15557 is a novel, competitive, long-acting, orally active DPP-4 inhibitor with a Ki value of 5.53 nM. It effectively inhibits plasma DPP-4 activity and is applicable for research in type 2 diabetes.Formule :C17H20F2N2O3SMasse moléculaire :370.41Gemigliptin tartrate hydrate
CAS :Gemigliptin (LC15-0444) tartrate hydrate is a selective, reversible, and competitive inhibitor of dipeptidyl peptidase 4 (DPP-4), with an IC50 value of 10.3 nM for human recombinant DPP-4. It exhibits strong anti-glycation properties and is used in research on advanced glycation end product-related diabetic complications.Formule :C22H27F8N5O9Couleur et forme :SolidMasse moléculaire :657.47PK44 phosphate
CAS :PK44 phosphate is a potent inhibitor of dipeptidyl peptidase IV (DPP-IV) (IC50: 15.8 nM).Formule :C17H19F5N7O5PCouleur et forme :SolidMasse moléculaire :527.349Gosogliptin hydrochloride
CAS :Gosogliptin hydrochloride is the hydrochloride salt of Gosogliptin. Gosogliptin (PF-00734200) is a potent, orally active selective competitive inhibitor of DPP-IV, which is primarily responsible for degrading the incretin hormones GLP-1 and glucose-dependent insulinotropic polypeptide. Gosogliptin rapidly and reversibly inhibits plasma DPP-4 activity, stimulates insulin secretion, and improves glucose tolerance.Formule :C17H26Cl2F2N6OMasse moléculaire :439.33DPP-4-IN-15
CAS :DPP-4-IN-15 (Compound 22) is a non-competitive inhibitor of dipeptidyl peptidase-4 (DPP-4) with an IC50 value of 8.24 μM.Formule :C17H14F3N3O2SCouleur et forme :SolidMasse moléculaire :381.372(2S,4R)-Teneligliptin
CAS :(2S,4R)-Teneligliptin is a selective inhibitor of dipeptidyl peptidase IV (DPP-4). It increases the concentration of active glucagon-like peptide-1 (GLP-1) in plasma, which in turn stimulates insulin secretion when blood glucose levels are elevated, thereby exhibiting hypoglycemic effects. (2S,4R)-Teneligliptin is a promising candidate for research in type 2 diabetes.Formule :C22H30N6OSCouleur et forme :SolidMasse moléculaire :426.578PB01
CAS :PB01 is a DPP-4 inhibitor with an IC50 of 15.66 nM. It effectively suppresses high glucose-induced ROS generation and mitochondrial superoxide production while significantly reducing the cellular expression of DPP-4. Additionally, PB01 notably lowers blood glucose levels in diabetic mice. It demonstrates excellent safety, exhibiting almost no cytotoxicity at a concentration of 100 μM. PB01 holds promise for research in the diabetes field.Formule :C18H21N5O3Couleur et forme :SolidMasse moléculaire :355.391AMG-222 tosylate
CAS :AMG-222 tosylate is a DPP-IV inhibitor in clinical development for type II diabetes.Formule :C39H47N9O6SCouleur et forme :SolidMasse moléculaire :769.91
