CymitQuimica logo
Cellules souche et Dérivés

Cellules souche et Dérivés

Les inhibiteurs de cellules souches sont des composés qui ciblent spécifiquement les voies de signalisation et les protéines impliquées dans le maintien, la différenciation et la prolifération des cellules souches. Ces inhibiteurs sont cruciaux pour comprendre la biologie des cellules souches et pour développer des stratégies visant à manipuler les cellules souches à des fins thérapeutiques, telles que la médecine régénérative et le traitement du cancer. En contrôlant le destin des cellules souches, ces inhibiteurs peuvent aider à orienter la différenciation des cellules souches en types cellulaires spécifiques ou à prévenir une croissance cellulaire indésirable. Chez CymitQuimica, nous offrons une sélection d'inhibiteurs de cellules souches de haute qualité pour soutenir vos recherches en biologie des cellules souches, biologie du développement et médecine régénérative.

Sous-catégories appartenant à la catégorie "Cellules souche et Dérivés"

Affichez 2 plus de sous-catégories

535 produits trouvés pour "Cellules souche et Dérivés"

Trier par

Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
produits par page.
  • BPN-15606 besylate


    BPN-15606 besylate is a potent oral γ-secretase regulator reducing Aβ42 and Aβ40 with good pharmacokinetics. IC50: 7 nM (Aβ42), 17 nM (Aβ40).
    Formule :C29H29FN6O4S
    Couleur et forme :Solid
    Masse moléculaire :576.64

    Ref: TM-T64081

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • MYF-03-176

    CAS :
    MYF-03-176 is an orally active TEAD1/3/4 inhibitor with IC₅₀ values of 47/32/71 nM. inhibits TEAD transcriptional activity and cancer cell growth, antitumour.
    Formule :C19H18F4N4O2
    Couleur et forme :Solid
    Masse moléculaire :410.37

    Ref: TM-T62074

    1mg
    146,00€
    5mg
    À demander
  • (3S,4R)-Tofacitinib

    CAS :
    (3S,4R)-Tofacitinib is an less active enantiomer of Tofacitinib. Tofacitinib is a JAK3 inhibitor(IC50 : 1 nM).
    Formule :C16H20N6O
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :312.37

    Ref: TM-T13427

    25mg
    1.639,00€
    50mg
    2.142,00€
    100mg
    2.790,00€
  • JAK3-IN-11

    CAS :
    JAK3-IN-11: potent oral JAK3 inhibitor (IC50=1.7 nM), noncytotoxic, >588-fold selectivity, blocks T-cell growth; useful in autoimmune research.
    Formule :C23H23N5O2
    Couleur et forme :Solid
    Masse moléculaire :401.46

    Ref: TM-T9811

    25mg
    1.369,00€
    50mg
    1.783,00€
    100mg
    2.250,00€
  • Londamocitinib

    CAS :
    Londamocitinib (JAK1-IN-7) is a selective and potent JAK1 inhibitor with anti-inflammatory activity.
    Formule :C28H31F2N7O4S
    Degré de pureté :98.64% - 99.56%
    Couleur et forme :Solid
    Masse moléculaire :599.65

    Ref: TM-T11706

    1mg
    170,00€
    5mg
    416,00€
    10mg
    567,00€
    25mg
    858,00€
    50mg
    1.108,00€
    100mg
    1.485,00€
    1mL*10mM (DMSO)
    537,00€
  • TEAD-IN-10

    CAS :
    TEAD-IN-10 (compound 15), a covalent inhibitor, exhibits selective and potent inhibitory activity against TEAD1 (IC 50 =14 nM), TEAD2 (IC 50 =179 nM), and TEAD3 (IC 50 =4 nM). This compound is utilized in cancer research [1].
    Formule :C15H14F3NO
    Couleur et forme :Solid
    Masse moléculaire :281.27

    Ref: TM-T87500

    10mg
    À demander
    50mg
    À demander
  • TEAD-IN-1

    CAS :
    TEAD-IN-1 (Compound 2) is an effective inhibitor of TEAD auto-palmitoylation with an IC50 of 603 nM. It enhances the interaction between TEAD and VGLL4, while diminishing the interaction between YAP and TEAD. TEAD-IN-1 is applicable for cancer research.
    Formule :C15H20F2N2O3S
    Couleur et forme :Solid
    Masse moléculaire :346.393

    Ref: TM-T204883

    10mg
    À demander
    50mg
    À demander
  • Tyk2-IN-3

    CAS :
    Tyk2-IN-3 is an inhibitor of Tyk2 pseudokinase (IC50: 485 nM).
    Formule :C25H24N6O3S2
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :520.63

    Ref: TM-T13233

    25mg
    À demander
    50mg
    À demander
    100mg
    À demander
  • YAP/TAZ inhibitor-3

    CAS :
    YAP/TAZ inhibitor-3 (Compound 24) is a YAP/TAZ inhibitor applicable for relevant research within the life sciences field.
    Formule :C21H18F3NO3
    Degré de pureté :99.63%
    Couleur et forme :Solid
    Masse moléculaire :389.37

    Ref: TM-T87651

    1mg
    90,00€
    5mg
    215,00€
    10mg
    344,00€
    25mg
    695,00€
    50mg
    1.108,00€
    100mg
    1.791,00€
    200mg
    2.412,00€
    1mL*10mM (DMSO)
    236,00€
  • PMMB-187

    CAS :
    PMMB-187, a selective STAT3 inhibitor, exhibits an IC50 of 1.81 μM in MDA-MB-231 cells. This compound induces apoptosis in MDA-MB-231 cells by inhibiting STAT3 transcriptional activity and nuclear translocation, reducing mitochondrial membrane potential, increasing reactive oxygen species (ROS) production, and upregulating the expression of apoptosis-related proteins. PMMB-187 is useful for research in the field of cancer.
    Formule :C27H23BrN2O6S2
    Couleur et forme :Solid
    Masse moléculaire :615.52

    Ref: TM-T200126

    25mg
    2.783,00€
    50mg
    3.905,00€
    100mg
    4.399,00€
  • Zelasudil

    CAS :
    Zelasudil (RXC007) is a Rho-related (ROCK) kinase inhibitor for the study of idiopathic pulmonary fibrosis and inflammation.
    Formule :C22H21F2N7O
    Degré de pureté :99.15%
    Couleur et forme :Solid
    Masse moléculaire :437.445

    Ref: TM-T69665

    1mg
    96,00€
    5mg
    172,00€
    10mg
    261,00€
    25mg
    444,00€
    50mg
    620,00€
    100mg
    865,00€
    1mL*10mM (DMSO)
    178,00€
  • JDTic

    CAS :
    JDTic, a 4-phenylpiperidine derivative distantly related to analgesics like meperidine and ketobemidone and more closely to the mu opioid antagonist alvimopan, exhibits a notably long duration of action, maintaining effects in animals for weeks following a single dose. This duration is not due to irreversible binding to the kappa opioid receptor but rather to altered activity of c-Jun N-terminal kinases. As a highly selective antagonist for the κ-opioid receptor, without influencing the μ- or δ-opioid receptors, JDTic has shown potential in animal studies for producing antidepressant and anxiolytic effects. It also demonstrates promise in treating addiction to substances such as cocaine and morphine, distinguishing itself structurally from other kappa antagonists like norbinaltorphimine.
    Formule :C28H39N3O3
    Couleur et forme :Solid
    Masse moléculaire :465.63

    Ref: TM-T11721

    5mg
    1.735,00€
    50mg
    3.509,00€
    100mg
    4.803,00€
  • CK2 inhibitor 2

    CAS :
    CK2 Inhibitor 2, characterized as a potent, selective, and orally active inhibitor of CK2, demonstrates an impressive IC50 value of 0.66 nM.
    Formule :C21H17ClN4O2
    Degré de pureté :99.02%
    Couleur et forme :Solid
    Masse moléculaire :392.84

    Ref: TM-T35557

    1mg
    65,00€
    5mg
    145,00€
    10mg
    226,00€
    25mg
    449,00€
    50mg
    672,00€
    100mg
    900,00€
    200mg
    1.216,00€
    1mL*10mM (DMSO)
    160,00€
  • TGFβRI-IN-3

    CAS :
    TGFβRI-IN-3 inhibits TGFβR1 with an IC 50 of 0.79 nM with 2000-fold selectivity against MAP4K4.
    Formule :C28H23N3O2S
    Degré de pureté :99.85%
    Couleur et forme :Soild
    Masse moléculaire :465.57

    Ref: TM-T9523

    1mg
    84,00€
    5mg
    177,00€
    10mg
    281,00€
    25mg
    552,00€
    50mg
    859,00€
    100mg
    1.234,00€
    500mg
    2.457,00€
    1mL*10mM (DMSO)
    177,00€
  • (3R,4S)-Tofacitinib

    CAS :
    (3R,4S)-Tofacitinib, the less active enantiomer of Tofacitinib, is a JAK3 inhibitor with an IC50 of 1 nM.
    Formule :C16H20N6O
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :312.37

    Ref: TM-T13426

    Produit arrêté
  • MF-Rat cTnT/TNNT2(Troponin T Type 2, Cardiac) ELISA Kit


    This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Rat cTnT/TNNT2. Samples (or Standards) are added to the micro ELISA plate wells and combined with the specific antibody and biotinylated detection antibody specific for Rat cTnT/TNNT2. Then Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Rat cTnT/TNNT2, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm. The OD value is proportional to the concentration of Rat cTnT/TNNT2. You can calculate the concentration of Rat cTnT/TNNT2 in the samples by comparing the OD of the samples to the standard curve.

  • MF-Rat TNNI3/cTn-I(Troponin I Type 3, Cardiac) ELISA Kit


    This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Rat TNNI3/cTn-I. Samples (or Standards) are added to the micro ELISA plate wells and combined with the specific antibody and biotinylated detection antibody specific for Rat TNNI3/cTn-I. Then Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Rat TNNI3/cTn-I, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm. The OD value is proportional to the concentration of Rat TNNI3/cTn-I. You can calculate the concentration of Rat TNNI3/cTn-I in the samples by comparing the OD of the samples to the standard curve.

  • MF-Mouse S100B(S100 Calcium Binding Protein B) ELISA Kit


    This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human S100B. Samples (or Standards) are added to the micro ELISA plate wells and combined with the specific antibody and biotinylated detection antibody specific for Human S100B. Then Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human S100B, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm. The OD value is proportional to the concentration of Human S100B. You can calculate the concentration of Human S100B in the samples by comparing the OD of the samples to the standard curve.

  • MF-Rat S100B(S100 Calcium Binding Protein B) ELISA Kit


    This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human S100B. Samples (or Standards) are added to the micro ELISA plate wells and combined with the specific antibody and biotinylated detection antibody specific for Human S100B. Then Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human S100B, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm. The OD value is proportional to the concentration of Human S100B. You can calculate the concentration of Human S100B in the samples by comparing the OD of the samples to the standard curve.

  • MF-Mouse TNNI3/cTn-I(Troponin I Type 3, Cardiac) ELISA Kit


    This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Mouse TNNI3/cTn-I. Samples (or Standards) are added to the micro ELISA plate wells and combined with the specific antibody and biotinylated detection antibody specific for Mouse TNNI3/cTn-I. Then Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Mouse TNNI3/cTn-I, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm. The OD value is proportional to the concentration of Mouse TNNI3/cTn-I. You can calculate the concentration of Mouse TNNI3/cTn-I in the samples by comparing the OD of the samples to the standard curve.

  • MF-Human cTnT/TNNT2(Troponin T Type 2, Cardiac) ELISA Kit


    This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human cTnT/TNNT2. Samples (or Standards) are added to the micro ELISA plate wells and combined with the specific antibody and biotinylated detection antibody specific for Human cTnT/TNNT2. Then Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human cTnT/TNNT2, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm. The OD value is proportional to the concentration of Human cTnT/TNNT2. You can calculate the concentration of Human cTnT/TNNT2 in the samples by comparing the OD of the samples to the standard curve.

  • MF-Human S100B(S100 Calcium Binding Protein B) ELISA Kit


    This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human S100B. Samples (or Standards) are added to the micro ELISA plate wells and combined with the specific antibody and biotinylated detection antibody specific for Human S100B. Then Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human S100B, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm. The OD value is proportional to the concentration of Human S100B. You can calculate the concentration of Human S100B in the samples by comparing the OD of the samples to the standard curve.

  • MF-Mouse cTnT/TNNT2(Troponin T Type 2, Cardiac) ELISA Kit


    This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Mouse cTnT/TNNT2. Samples (or Standards) are added to the micro ELISA plate wells and combined with the specific antibody and biotinylated detection antibody specific for Mouse cTnT/TNNT2. Then Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Mouse cTnT/TNNT2, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm. The OD value is proportional to the concentration of Mouse cTnT/TNNT2. You can calculate the concentration of Mouse cTnT/TNNT2 in the samples by comparing the OD of the samples to the standard curve.

  • MF-Human TNNI3/cTn-I(Troponin I Type 3, Cardiac) ELISA Kit


    This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human TNNI3/cTn-I. Samples (or Standards) are added to the micro ELISA plate wells and combined with the specific antibody and biotinylated detection antibody specific for Human TNNI3/cTn-I. Then Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human TNNI3/cTn-I, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm. The OD value is proportional to the concentration of Human TNNI3/cTn-I. You can calculate the concentration of Human TNNI3/cTn-I in the samples by comparing the OD of the samples to the standard curve.

  • JAK2-IN-9

    CAS :

    Compound A8, known as JAK2-IN-9, is a selective JAK2 inhibitor with an IC50 of 5 nM.

    Formule :C20H24N6O2S
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :412.51
  • JAK1-IN-10

    CAS :

    JAK1-IN-10 (compound 9), a cyano-substituted cyclic hydrazine derivative, functions as a potent and selective inhibitor of JAK1 [1].

    Formule :C15H17N7
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :295.34
  • JAK-IN-34

    CAS :

    JAK-IN-34 (compound 11n) is a potent inhibitor of Janus kinases (JAKs), demonstrating IC50 values of 0.40 nM for JAK1, 0.83 nM for JAK2, 2.10 nM for JAK3,

    Formule :C27H26N6O
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :450.53
  • DPP

    CAS :

    DPP, a Platinum(IV) complex with a pterostilbene-derived axial ligand, inhibits the JAK2-STAT3 pathway in breast cancer (BC) cells, demonstrating

    Formule :C36H40Cl2N2O10Pt
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :926.7
  • JAK1-IN-11

    CAS :

    JAK1-IN-11 (compound 11) serves as a potent inhibitor of Janus kinases, exhibiting nanomolar inhibitory concentrations with IC50 values of 0.02 nM (JAK1) and 0.

    Formule :C26H36N6O4S
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :528.67
  • STAT3-IN-18

    CAS :

    STAT3-IN-18 (compound SPP), a platinum (IV) complex featuring an axial ligand from sandalwood, suppresses the JAK2-STAT3 pathway in breast cancer (BC) cells and

    Formule :C18H24Cl2N2O6Pt
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :630.38
  • JAK-IN-27

    CAS :

    JAK-IN-27, also known as compound 1, is an orally active, potent inhibitor of the JAKS family kinases, displaying inhibitory concentrations (IC50s) of 3.0 nM

    Formule :C20H21F2N7O
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :413.42
  • ROCK2-IN-6

    CAS :

    ROCK2-IN-6 (Comp A) is a selective inhibitor of ROCK2, applicable in the study and treatment of ROCK-mediated, autoimmune, and inflammatory diseases [1].

    Formule :C26H21F2N7O
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :485.49
  • ROCK-IN-6

    CAS :

    ROCK-IN-6, a selective ROCK2 inhibitor, exhibits potent inhibition with an IC50 of 2.19 nM and holds promise for research into glaucoma and retinal diseases [1

    Formule :C19H19N5O8S
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :477.45
  • WHN-88

    CAS :

    WHN-88, a Porcupine (PORCN) inhibitor, disrupts the palmitoylation of Wnt ligands, which inhibits their secretion and subsequent Wnt/β-catenin signaling. This compound has shown efficacy in reducing cancer cell stemness and suppressing the progression and development of breast tumors in MMTV-Wnt1 transgenic mice.

    Formule :C18H13I2N3O2
    Couleur et forme :Solid
    Masse moléculaire :557.12
  • DCN1-IN-2

    CAS :

    DCN1-IN-2, a DCN1 inhibitor, exhibits potent activity with an IC 50 of 2.96 nM. It effectively mitigates Ang II/TGFβ-induced activation of cardiac fibroblasts and diminishes ISO-induced cardiac fibrosis and remodeling in mice through the selective inhibition of cullin 3.

    Formule :C18H14ClF3N4OS
    Couleur et forme :Solid
    Masse moléculaire :426.84